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CN219646351U - Sterilization filter for high-pressure sterilizer - Google Patents

Sterilization filter for high-pressure sterilizer Download PDF

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Publication number
CN219646351U
CN219646351U CN202320708537.8U CN202320708537U CN219646351U CN 219646351 U CN219646351 U CN 219646351U CN 202320708537 U CN202320708537 U CN 202320708537U CN 219646351 U CN219646351 U CN 219646351U
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CN
China
Prior art keywords
pipeline
sealed box
filter
input
sterilizing filter
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Active
Application number
CN202320708537.8U
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Chinese (zh)
Inventor
沈继武
张跃鑫
王明恩
陈春
鞠平进
罗万坤
曹敏静
马中杰
孙砚龙
角锋
杨思远
谢红
董芳文
王晓涛
阮茂
徐巍
和浩龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Medical Biology of CAMS and PUMC
Original Assignee
Institute of Medical Biology of CAMS and PUMC
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Application filed by Institute of Medical Biology of CAMS and PUMC filed Critical Institute of Medical Biology of CAMS and PUMC
Priority to CN202320708537.8U priority Critical patent/CN219646351U/en
Application granted granted Critical
Publication of CN219646351U publication Critical patent/CN219646351U/en
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Abstract

The utility model provides a sterilizing filter for an autoclave, which comprises a sealed box body with a box door arranged on the sterilizing filter, and is characterized in that the sealed box body is arranged in a clean area, the sealed box body is internally provided with a sterilizing filter, the input end of the sterilizing filter is communicated with an external air compressor and a steam generator through an input pipeline, the output end of the sterilizing filter is communicated with the autoclave and a drainage pipeline through an output pipeline, a valve and a quick connector for connection are respectively arranged on the input pipeline and the output pipeline in the sealed box body, and a quick connector for testing the integrity of the sterilizing filter is also arranged on the integrity testing end and the output pipeline. Through setting up the sealed box in clean district, make the degerming filter be in clean district environment, not polluted by unclean district exogenous impurity, through input, output pipeline and valve, the quick-operation joint on, make things convenient for degerming filter dismouting, test, simplify the operation, raise the efficiency, reduce the risk.

Description

Sterilization filter for high-pressure sterilizer
Technical Field
The utility model relates to a sterilization filter, in particular to a sterilization filter for an autoclave, belonging to the technical field of biological pharmacy.
Background
In the biopharmaceutical industry, autoclaves are often used for autoclaving, the specific operating steps (taking equipment procedures as examples) are as follows: charging, vacuumizing, steam inlet heating, sterilization, vacuum drying, air supplementing, vacuum relief and material taking. That is, after sterilization is completed, clean compressed air treated by a sterilizing filter needs to be supplemented into the sterilizer cavity in a vacuum state to balance the pressure in the sterilizer cavity (namely, the vacuum is released to normal pressure), so that the requirement of safe door opening is met. Currently, the sterilizing filters are usually mounted directly on the autoclave, with their entirety inside the technical tunnels of the GMP unclean zone, with the risk of contamination by contaminants external to the unclean zone when the sterilizing filters are replaced or maintained. Meanwhile, the method is limited by the environment and the condition of a technical channel, the field integrity test of the sterilizing filter cannot be carried out, and the real-time observation of the working state of the sterilizing filter is inconvenient. There is a need for improvements over existing mounting structures.
Disclosure of Invention
The utility model provides a sterilization filter for an autoclave, which aims to solve the problems that the sterilization filter equipped in the existing biopharmaceutical autoclave is unreasonable in installation position, is easy to be polluted by exogenous pollutants in the using process, is inconvenient to carry out integrity test and real-time observation of working state on the sterilization filter and the like.
The utility model is completed by the following technical scheme: the utility model provides a sterilizing filter for autoclave, including the sealed box who establishes the chamber door on it, its characterized in that sealed box sets up in clean area, be equipped with sterilizing filter in the sealed box, sterilizing filter input is linked together with outside air compressor and steam generator through the input pipeline, sterilizing filter output is linked together with autoclave and drainage pipe through the output pipeline, be equipped with valve and quick-operation joint for connection on the input, the output pipeline that lie in the sealed box respectively, and sterilizing filter integrality test end and output pipeline are last still to be equipped with the quick-operation joint for test of connection integrality tester, guarantee sterilizing filter in clean area environment through the sealed box that sets up in clean area, reduce the risk of being polluted by unclean area exogenous pollutant when realizing sterilizing filter change dismouting and integrality test, through the input, output pipeline and valve, the quick-operation joint on, convenient sterilizing filter's change dismouting and integrality test, the operation is simplified, raise efficiency, reduce the risk.
The sealed box body is a rectangular steel box body with a cavity therein, the box door is arranged on the front surface of the sealed box body and is a transparent sealing door, or is a steel sealing door with an observation window arranged thereon, the clean environment in the box is ensured through effective sealing and isolation of the sealed box body and the unclean area, and the working state of the filter is conveniently observed and mastered in real time through the transparent box door or the observation window.
The degerming filter is fixed in the sealed box cavity through the support, is equipped with input, output and test end on the degerming filter respectively, wherein: the input end of the sterilizing filter is connected with the inner end of the input pipeline, the outer end of the input pipeline passes through the sealed box body and then is respectively connected with a first group of branch pipes provided with external valves on the input pipeline through a first tee joint, the first group of branch pipes are respectively connected with an external air compressor and a steam generator, the output end of the sterilizing filter is connected with the inner end of the output pipeline, the outer end of the output pipeline passes through the sealed box body and then is respectively connected with a second group of branch pipes provided with external valves on the output pipeline through a second tee joint, and the second group of branch pipes are respectively communicated with the high-pressure sterilizer and the drainage pipeline so as to perform sterilizing filtration on the compressed air fed into the high-pressure sterilizer through the sterilizing filter.
The two quick connectors for connection are respectively arranged at the disconnection positions of the input pipeline and the output pipeline in the sealed box body, so that the quick separation and connection of the filter and the input pipeline and the output pipeline are realized through the quick connectors, and the filter replacement efficiency is improved.
The quick connector for testing is arranged on the test end of the sterilizing filter and the output pipeline in the sealing box body respectively, one end of the quick connector for testing is communicated with the test end of the sterilizing filter and the output pipeline in the sealing box body, and the other end of the quick connector for testing is provided with a quick-release blind plate so as to be quickly connected with an integrity tester when in integrity test, and the quick connector for testing is sealed through the quick-release blind plate when not in use.
The utility model has the following advantages and effects: by adopting the scheme, the sterilizing filter is ensured to be in the clean area environment through the sealing box body arranged in the clean area, the risk of being polluted by foreign pollutants in the unclean area is reduced when the sterilizing filter is replaced, disassembled and tested in integrity, and the disassembly and the assembly and the testing of the filter are facilitated through the input pipeline, the output pipeline, the valve and the quick connector on the input pipeline and the output pipeline, so that the operation is simplified, the efficiency is improved and the risk is reduced. The sterilizing filter box body is designed into an independent multifunctional integrated system, so that normal operation, sterilizing operation and real-time observation of the sterilizing filter can be realized when the sealing door is closed, and the sterilizing filter integrity test in an online mode or an offline mode and the convenient and quick sterilizing filter replacement operation can be realized when the sealing door is opened.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model.
Detailed Description
The utility model is further described below with reference to the accompanying drawings.
The utility model provides a sterilization filter for an autoclave, which comprises a sealing box body 12, wherein a box door is arranged on the sealing box body 12, the sealing box body 12 is arranged in a clean area, a sterilization filter 6 is arranged in the sealing box body 12, the input end of the sterilization filter 6 is communicated with an external air compressor 1 and a steam generator 2 through an input pipeline 4, the output end of the sterilization filter 6 is communicated with an autoclave 9 and a drainage pipeline 10 through an output pipeline 8, a valve 5 and a quick connector 11 for connection are respectively arranged on the input pipeline 4 and the output pipeline 8 which are positioned in the sealing box body 12, and a quick connector 7 for test which is connected with a tester is also arranged on the test end of the sterilization filter 6 and the output pipeline 8, so that the sterilization filter is ensured to be in a sterilization environment through the sealing box body 12 arranged in the clean area, the risk of being polluted by exogenous pollutants in a non-clean area during disassembly and assembly and integrity test is avoided, and disassembly and assembly of the sterilization filter 6 are facilitated, operation is simplified, efficiency is improved, and risks are reduced through the input pipeline and the valves and the quick connectors on the output pipeline;
the sealed box body 12 is a rectangular steel box body with a cavity therein, the box door is arranged on the front surface of the sealed box body and is a transparent sealed box door, so that the clean environment in the box is further ensured through the sealed box body 12, and the working state of the sterilizing filter 6 is conveniently observed and mastered in real time through the transparent sealed box door;
the sterilizing filter 6 is set as a conventional product, and is fixed in the cavity of the sealed box body 12 through a bracket, and an input end, an output end and a test end are respectively arranged on the sterilizing filter 6, wherein: the input end of the sterilizing filter 6 is connected with the inner end of the input pipeline 4, the outer end of the input pipeline 4 passes through the sealed box 12 and then is respectively connected with a first group of branch pipes provided with external valves 3 on the input pipeline through a first tee joint, the first group of branch pipes are respectively connected with an external air compressor 1 and a steam generator 2, the output end of the sterilizing filter 6 is connected with the inner end of the output pipeline 8, the outer end of the output pipeline 8 passes through the sealed box 12 and then is respectively connected with a second group of branch pipes provided with external valves on the output pipeline through a second tee joint, and the second group of branch pipes are respectively communicated with the high-pressure sterilizer 9 and the drainage pipeline 10 so as to perform sterilizing filtration on compressed air fed into the high-pressure sterilizer 9 through the sterilizing filter 6;
the two quick connectors 11 for connection are respectively arranged at the disconnection positions of the input pipeline 4 and the output pipeline 8 in the sealed box body 12, so that the quick separation and connection of the sterilizing filter 6 and the input pipeline 4 and the output pipeline 8 are realized through the quick connectors, and the replacement efficiency of the sterilizing filter 6 is improved;
the quick connector 7 for test is set to two, and it locates on the output pipeline 8 in degerming filter 6 test end and the sealed box respectively, and quick connector 7 for test one end is linked together with degerming filter 6 test end and the output pipeline 8 in the sealed box, and the other end is equipped with quick detach blind plate to when carrying out the integrality test, with integrality tester quick connect, seal the quick connector for test through quick detach blind plate when not using.

Claims (5)

1. The utility model provides a sterilization filter for autoclave, includes the sealed box who establishes the chamber door on it, its characterized in that sealed box sets up in clean area, is equipped with sterilization filter in the sealed box, and sterilization filter input is linked together with outside air compressor and steam generator through input pipeline, and sterilization filter output is linked together with autoclave and drainage pipe through output pipeline, is equipped with valve and quick-operation joint for connection respectively on being located the input, the output pipeline of sealed box to still be equipped with the quick-operation joint for connection integrity tester on sterilization filter integrality test end and the output pipeline.
2. The sterilizing filter for autoclave according to claim 1, wherein the sealing case is a rectangular steel case having a cavity therein, and the door is provided on the front surface of the sealing case as a transparent sealing door or as a steel sealing door having an observation window provided thereon.
3. The sterilization filter for an autoclave according to claim 1, wherein the sterilization filter is fixed in the cavity of the sealed case body by a bracket, and is provided with an input end, an output end and a test end, respectively, wherein: the input end of the sterilizing filter is connected with the inner end of an input pipeline, the outer end of the input pipeline passes through the sealed box body and then is respectively connected with a first group of branch pipes on which external valves are arranged through a first tee joint, the first group of branch pipes are respectively connected with an external air compressor and a steam generator, the output end of the sterilizing filter is connected with the inner end of an output pipeline, the outer end of the output pipeline passes through the sealed box body and then is respectively connected with a second group of branch pipes on which external valves are arranged through a second tee joint, and the second group of branch pipes are respectively communicated with the high-pressure sterilizer and a drainage pipeline.
4. The sterilizing filter according to claim 1, wherein the number of the quick connectors for connection is two, and the quick connectors are respectively arranged at the disconnection position of the input pipeline and the output pipeline in the sealed box body.
5. The sterilizing filter for autoclave according to claim 1, wherein the number of the quick connectors for the integrity test is two, the quick connectors are respectively arranged on the testing end of the sterilizing filter and the output pipeline in the sealed box body, one end of the quick connector for the test is communicated with the testing end of the sterilizing filter and the output pipeline in the sealed box body, and the other end of the quick connector for the test is provided with a quick-dismantling blind plate.
CN202320708537.8U 2023-04-03 2023-04-03 Sterilization filter for high-pressure sterilizer Active CN219646351U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202320708537.8U CN219646351U (en) 2023-04-03 2023-04-03 Sterilization filter for high-pressure sterilizer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202320708537.8U CN219646351U (en) 2023-04-03 2023-04-03 Sterilization filter for high-pressure sterilizer

Publications (1)

Publication Number Publication Date
CN219646351U true CN219646351U (en) 2023-09-08

Family

ID=87879256

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202320708537.8U Active CN219646351U (en) 2023-04-03 2023-04-03 Sterilization filter for high-pressure sterilizer

Country Status (1)

Country Link
CN (1) CN219646351U (en)

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