CN217787122U - Chemiluminescence immune analyzer capable of adding liquid and detecting instantly - Google Patents

Abstract

The utility model discloses a chemiluminescence immunoassay appearance, chemiluminescence immunoassay appearance includes shell and analyzer body, and the analyzer body includes: reaction cup, reaction cup support, reaction cup moving mechanism, liquid feeding needle, photomultiplier. The utility model is suitable for a same treat the immunoreaction that the sample needs add multiple reagent to go on according to the precedence, can carry out the luminous detection and the analysis of reactant immediately, improved the efficiency of detection and analysis.

Description

A chemiluminescence immunoassay analyzer for instant liquid addition and detection

technical field

The utility model belongs to the technical field of in vitro diagnostic equipment, in particular to a chemiluminescent immune analyzer for instant liquid addition and detection.

Background technique

Chemiluminescence analyzers have the advantages of high sensitivity, high degree of automation, and fast sample processing speed, and have become the main means of immunoassay diagnosis. However, large-scale automatic chemiluminescence immunoassay analyzers are expensive, bulky and complex in structure.

With the development of technology, the emergence of some small chemiluminescent immunoassay analyzers has made up for the shortcomings of large analyzers. For example, Chinese patent CN216051761U discloses a fully automatic chemiluminescence immunoassay analyzer, but there is only one sample needle in this miniaturized analyzer, and the same sample needle is used to draw the sample and reagent. Needs to be cleaned. This kind of analyzer is not suitable for the chemiluminescence immunoreaction in which the luminescence reaction detection is performed immediately after the same sample to be tested and two or more reagents are successively added in sequence.

Utility model content

In order to adapt to the continuous reaction between the same sample to be tested and different reagents in sequence, the immune reaction analysis of luminescent reaction detection is performed immediately, and the efficiency of detection and analysis is improved.

The utility model provides a chemiluminescent immune analyzer for instant liquid addition and detection, which comprises a shell and an analyzer body. The analyzer body includes:

cuvette for chemiluminescence immunoreaction;

A cuvette holder, used to fix the cuvette, a groove for holding the cuvette is arranged on the cuvette holder;

a reaction cup moving mechanism, used to drive the reaction cup holder and the reaction cup to move in the horizontal direction, and the reaction cup moving mechanism is fixedly connected with the reaction cup holder;

A liquid addition needle is used to add a chemiluminescent immune reaction solution into the cuvette, the liquid addition needle is arranged above the cuvette moving mechanism, and the liquid addition needle can move up and down;

The photomultiplier tube is used to detect the chemiluminescent immune reaction in the cuvette, and the photomultiplier tube is fixed on the bottom plate of the housing.

Preferably, the number of cuvettes is determined according to the number of samples to be analyzed and the number of parallel immune reaction experiments, there are at least two cuvettes, and the cuvettes are arranged side by side. Further preferably, there are 3-9 cuvettes, such as 3, 4, 5, 6, 7, 8 or 9 cuvettes.

Preferably, the number of liquid addition needles is determined according to the types of reagents participating in the immune reaction, and each liquid addition needle corresponds to one reagent. There are at least two liquid-filling needles, and the liquid-filling needles are arranged side by side. Further preferably, the distance between two adjacent liquid filling needles is equal to the distance between two adjacent cuvettes. When the same cuvette passes through the liquid adding needle sequentially, it can ensure that different reagents are accurately added to the same cuvette.

In a specific embodiment of the present invention, the body of the chemiluminescence immunoassay analyzer further includes a liquid filling pump, and the liquid adding pump is airtightly connected with the liquid filling needle through a pipeline. The dosing pump mainly pumps the chemiluminescence immunoreaction reagent into the dosing needle, and further injects it into the cuvette.

Preferably, the filling pumps are in one-to-one correspondence with the filling needles, and the filling pumps are fixed on the bottom plate of the casing.

Preferably, any one of bolts, riveting and welding may be used for the fixing, more preferably bolt fixing.

In a specific embodiment of the present invention, the cuvette holder is used to fix the cuvette, and positioning holes are arranged on the cuvette holder. Preferably, the number of the positioning holes is at least one, more preferably two or three. The positions of the positioning hole and the groove are relatively fixed, and when only one positioning hole is provided, the position of the positioning hole can be determined through the groove.

Preferably, the number of the grooves is greater than or equal to the number of the cuvettes, and further preferably, the grooves correspond to the cuvettes one by one.

Preferably, positioning pins are provided on the cuvette moving mechanism, and the positions of the positioning pins correspond to the positions of the positioning holes. fixed on the cuvette moving mechanism.

Preferably, the cuvette moving mechanism includes a first driving motor, a first slide rail and a first slider.

The first drive motor provides power for the horizontal movement of the cuvette holder;

The first slide rail is connected to the first drive motor, and the first slide rail can move in the horizontal direction;

The first sliding block is fixedly connected with the first sliding rail, the positioning pin is arranged on the first sliding block, and the first sliding block can move horizontally along the first sliding rail.

In another specific embodiment of the present utility model, the body of the chemiluminescence immunoassay analyzer further includes a fixing seat for a liquid filling needle. The liquid filling needle fixing seat is fixedly connected with the liquid adding needle, so as to ensure that the positions of the liquid filling needle and the liquid filling needle fixing seat are relatively fixed. When the liquid-filling needle fixing seat moves up and down in the vertical direction, it can drive the liquid-filling needle to move up and down synchronously.

Preferably, the fixed connection is a detachable connection or a non-detachable connection.

Preferably, the detachable connection is a threaded connection or a buckle connection, more preferably a threaded connection.

Preferably, the non-detachable connection is one of a rivet connection, an adhesive connection or a welded connection, more preferably a welded connection.

Preferably, the chemiluminescence immunoassay analyzer body further includes a moving mechanism for a liquid filling needle, which can move up and down in a vertical direction. The moving mechanism of the liquid filling needle is fixedly connected with the fixed seat of the liquid filling needle, so as to ensure that the fixed seat of the liquid filling needle and the moving mechanism of the liquid adding needle can move synchronously along the vertical direction.

Preferably, the fixed connection is a detachable connection or a non-detachable connection.

Preferably, the detachable connection is one of threaded connection, buckle connection or hinged connection, more preferably threaded connection.

Preferably, the non-detachable connection is one of a rivet connection, an adhesive connection or a welded connection, more preferably a welded connection.

Preferably, the liquid filling needle moving mechanism includes a second driving motor, a second sliding rail and a second sliding block. The second drive motor provides driving force for the movement of the liquid filling needle holder, the second slide rail is in transmission connection with the second drive motor, and the second slide rail can move up and down in the vertical direction.

The second slide block is fixedly connected with the second slide rail, and the second slide block can move up and down along the second slide rail.

Preferably, the liquid-filling needle fixing seat is fixedly connected with the second slider, so that the liquid-filling needle fixing seat can move up and down vertically along the second slide rail.

Preferably, the fixed connection is a detachable connection or a non-detachable connection.

Preferably, the detachable connection is one of threaded connection, buckle connection or hinged connection, more preferably threaded connection.

Preferably, the non-detachable connection is one of a rivet connection, an adhesive connection or a welded connection, more preferably a welded connection.

More preferably, the first driving motor and the second driving motor are stepping motors, and the first sliding rail and the second sliding rail are screw rods.

In a specific embodiment of the present invention, the body of the chemiluminescent immunoassay analyzer further includes a base, the base is used to fix the cuvette moving mechanism and the liquid adding needle moving mechanism, and the base is fixed to the bottom plate of the enclosure.

Preferably, the chemiluminescence immunoassay analyzer body further includes a light-shielding cover, and the light-shielding cover moves the cuvette moving mechanism, the cuvette, the cuvette holder, and the liquid-filling needle from around and above. , the liquid-feeding needle fixing seat and the liquid-feeding needle moving mechanism surround, the light-shielding cover is fixed on the base of the chemiluminescence immunoassay analyzer body, and then fixed on the bottom plate of the shell, the A photometric hole for the photomultiplier tube to detect the chemiluminescent immune reaction is arranged on the light shield.

In a specific embodiment of the present utility model, on the side wall of the light-shielding cover opposite to the first drive motor and close to the end of the cuvette support, there is a The first slide rail enters and exits the side door of the light shield.

Preferably, the side door is provided with a first side plate, the first side plate is magnetically attracted to the edge of the side door, and the side of the cuvette holder can be connected to the first side plate by magnetic force.

Preferably, a door is provided on the side wall of the housing, so that the cuvette holder can slide out of the housing along the first slide rail, so as to place or replace the cuvette.

More preferably, when the cuvette holder enters the housing, the door can be closed.

Preferably, a power interface is provided on the side panel of the housing, and a switch button for running the chemiluminescence immunoassay analyzer is provided on the top panel of the housing.

In another embodiment of the present utility model, a circuit control panel is provided on the back side of the light shield to control the operation of the chemiluminescence immunoassay analyzer according to a preset program.

The beneficial effects of the utility model:

The chemiluminescence immunoassay analyzer of the utility model can be applied to the same sample to be tested, which needs to be reacted by adding various reagents in sequence, and finally immediately conducts immunoreaction analysis of luminescence detection, thereby improving the efficiency of detection and analysis.

Description of drawings

Fig. 1 is the shell structure schematic diagram of the present utility model;

The markings of the components in the figure are as follows: 101 - warehouse door, 102 - switch button, 103 - power interface;

Fig. 2 is a schematic cross-sectional view of the body structure of the chemiluminescent immune analyzer of the present invention;

The markings of the components in the figure are as follows: 201-the first driving motor, 202-the first slide rail, 203-the first slider, 204-photometric hole, 205-fixing seat of liquid filling needle, 206-first liquid filling needle , 207-second liquid addition needle, 208-reaction cup, 209-reaction cup support, 210-base;

Fig. 3 is a schematic diagram of an exploded structure of the utility model;

The markings of the components in the figure are as follows: 301-the second slide rail, 302-the second drive motor screw, 303-the second slide block;

Fig. 4 is an enlarged schematic diagram of the liquid-feeding needle moving mechanism of the present invention;

The marks of each part in the figure are as follows: 401-the second driving motor;

Fig. 5 is the second schematic diagram of the decomposition structure of the utility model;

The marks of the components in the figure are as follows: 501-the first filling pump, 502-the second filling pump, 503-photomultiplier tube, 504-control panel;

Fig. 6 is a schematic structural view of the cuvette before placement of the utility model;

The marks of each part in the figure are as follows; 601-locating pin;

Fig. 7 is a structural schematic diagram of the utility model after the cuvette is placed;

Fig. 8 is a structural schematic diagram of the reaction cup and the reaction cup support of the utility model;

The marks of each part in the figure are as follows: 701-positioning hole, 702-groove.

Detailed ways

The technical solutions of the utility model will be further described below in conjunction with the accompanying drawings and embodiments, and the advantages and characteristics of the utility model will become clearer along with the description. However, it should be understood that the embodiments are only exemplary and do not limit the scope of the present utility model.

It should be noted that the directions or directions indicated by the terms "upper", "lower", "left", "right", "top", "bottom" and "side" in the claims of this application document and the specification The positional relationship is based on the orientation or positional relationship shown in the drawings, and it is not necessarily understood that the devices or components referred to must have a specific orientation, be configured in a specific orientation, or operate. In addition, "first" and "second" in this application document are only used to describe similar objects, and are not necessarily interpreted as a specific order or sequence.

In a specific embodiment of the present invention, the chemiluminescence immunoassay analyzer includes a housing and a body. The shell part (see Fig. 1) mainly includes a side plate, a bottom plate, a cover plate and a bottom support leg, a door 101, a power interface 103 are arranged on the side plate, and an on/off button 102 is arranged on the cover plate. The door 101 is the channel for detecting samples to enter and exit the chemiluminescence immunoassay analyzer, the power interface 103 is used for the chemiluminescence immunoassay analyzer to connect to an external working power supply, and the switch button 102 is a control button for running and stopping the chemiluminescence immunoassay analyzer.

As shown in Fig. 2, Fig. 3, Fig. 4 and Fig. 5, the body of the chemiluminescence immunoassay analyzer includes an immune response system, a moving mechanism of the immune response system and a detection system. The immune reaction system includes a reaction cup 208 , a reaction cup holder 209 , a first liquid addition needle 206 , a second liquid addition needle 207 , a liquid addition needle holder 205 , a first liquid addition pump 501 and a second liquid addition pump 502 . The moving mechanism of the immune reaction system includes a cuvette moving mechanism moving in the horizontal direction and a liquid filling needle moving mechanism moving in the vertical direction. The cuvette moving mechanism includes a first driving motor 201 , a first sliding rail 202 and a first sliding block 203 . The liquid filling needle moving mechanism includes a second driving motor 401 , a second driving motor screw 302 , a second sliding rail 301 and a second sliding block 303 . The detection system is used to detect the luminescent phenomenon during the immune reaction, which includes a photomultiplier tube 503 and a photometric hole 204 .

As shown in FIG. 2 and FIG. 8 , in the immune reaction system, the cuvette 208 is used to contain the sample to be detected and the reaction reagent. In a chemiluminescence immunoassay analyzer, at least two cuvettes 208 can be set at the same time, and the specific number of cuvettes 208 is set according to the number of samples to be tested and the number of parallel experiments for each sample to be tested. The cuvettes 208 for participating in the chemiluminescence immunoreaction are preferably arranged side by side. The number of cuvettes in Fig. 2 is 8 and arranged in a row. The cuvette holder 209 is used to fix and support the cuvette 208 to ensure the stability of the cuvette 208 . A groove 702 is provided on the cuvette holder 209 , and the groove 702 is mainly used for fixing the cuvette 208 on the cuvette holder 209 . The number of grooves 702 is greater than or equal to the number of cuvettes 208, preferably the grooves 702 correspond to the cuvettes 208 one by one, for example, the number of grooves 702 in FIG. 8 is 8. All the grooves 702 are arranged side by side, and the distance between adjacent grooves 702 is the same, so as to ensure that the distance between adjacent cuvettes 208 is also the same.

In one embodiment of the present utility model, positioning holes 701 are also provided on the cuvette support 209. As shown in FIG. , preferably two or three can be set. The positions of the positioning hole 701 and the groove 702 are relatively fixed. When only one positioning hole 701 is provided, the groove 702 can be used to assist in determining the position of the positioning hole 701 .

As shown in FIGS. 2 and 5 , the liquid addition needle holder 205 , the first liquid addition needle 206 , the second liquid addition needle 207 , the first liquid addition pump 501 and the second liquid addition pump 502 are used to inject the liquid into the cuvette 208 The reaction reagent is added, so that the substrate of the sample to be detected reacts with the reaction reagent to generate a luminescent phenomenon for detecting the progress of the reaction. The first liquid filling needle 206 and the second liquid filling needle 207 are fixedly connected to the liquid filling needle fixing seat 205, and the liquid filling needle and the liquid adding needle fixing seat 205 can be connected in a detachable manner, such as threaded connection or buckle connection, Preferably a threaded connection. The liquid-filling needle and the liquid-filling needle fixing seat 205 can also be non-detachably connected, such as one of rivet connection, adhesive connection or welding connection, preferably welding connection. The first filling needle 206 and the first filling pump 501 are airtightly connected through a pipeline. In order to accommodate the first liquid adding needle 206 to move up and down in the vertical direction, the pipeline can be a hose, such as a silicone tube. The second filling needle 207 and the second filling pump 502 are also airtightly connected through pipelines. When the liquid addition pump is connected to the reaction reagent container, the reaction reagent can be pumped into the liquid addition needle and further injected into the reaction cup 208 . The number of liquid addition needles is set correspondingly according to the type of reaction reagent, preferably one liquid addition needle corresponds to one reaction reagent. The number of the liquid addition pumps is preferably the same as the number of the liquid addition needles, and there is a one-to-one correspondence between the two. When the number of liquid addition needles is greater than or equal to 2, the liquid addition needles are arranged side by side, and the distance between two adjacent liquid addition needles is equal to the distance between two adjacent cuvettes 208 . When the cuvettes 208 move horizontally at a constant speed, it can be ensured that the reagents in the liquid filling needles are accurately added to the adjacent cuvettes 208 in sequence.

As shown in FIG. 2 and FIG. 3 , the cuvette moving mechanism includes a first driving motor 201 , a first sliding rail 202 and a first sliding block 203 . The first drive motor 201 provides power for the horizontal movement of the cuvette holder 209 , and the first drive motor 201 is in transmission connection with the first slide rail 202 . When the first driving motor 201 is a stepper motor, the first slide rail 202 is a corresponding screw. The first sliding rail 202 and the first sliding block 203 are fixedly connected, and detachable connection can be selected, such as one of threaded connection, buckle connection or hinged connection, preferably threaded connection. A non-detachable connection can also be selected, such as one of a rivet connection, an adhesive connection or a welded connection, preferably a welded connection. Driven by the first slide rail 202 , the first slider 203 can horizontally move left and right along the first slide rail 202 . The first slider 203 is provided with a positioning pin 601 (see FIG. 6 ), and the positioning pin 601 corresponds to the positioning hole 701 on the cuvette support 209 (see FIG. 8 ). Through the cooperation of the positioning pin 601 and the positioning hole 701, the cuvette support 209 is fixed on the first slider 203, so that when the first slider 203 moves left and right in the horizontal direction, it can drive the cuvette support 209 to move synchronously, and then drive the cuvette 208 synchronized horizontal movement.

As shown in FIG. 2 , FIG. 3 and FIG. 4 , the liquid filling needle moving mechanism includes a second driving motor 401 , a second driving motor screw 302 , a second sliding rail 301 and a second sliding block 303 . The second driving motor 401 provides power for the liquid filling needle holder 205 to move up and down in the vertical direction, and the second driving motor 401 is in transmission connection with the second slide rail 301 . When the second drive motor 401 is a stepper motor, the second slide rail 301 is a corresponding screw. The second sliding rail 301 and the second sliding block 303 are fixedly connected, and detachable connection can be selected, such as one of threaded connection, buckle connection or hinged connection, preferably threaded connection. A non-detachable connection can also be selected, such as one of a rivet connection, an adhesive connection or a welded connection, preferably a welded connection. Driven by the second slide rail 301 , the second slide block 303 can vertically move up and down along the second slide rail 301 . The second slider 303 is fixedly connected with the liquid filling needle fixing seat 205 , such as threaded connection, buckle connection, rivet connection, welding and the like. Thus, the liquid-filling needle fixing seat 205, the liquid-filling needle and the second slide rail 301 are fixed together, and the liquid-filling needle is fixed on the second slide block 303, so that the second slide block 303 goes up and down vertically along the second slide rail 301 When moving, it can drive the liquid-filling needle fixing seat 205 to move synchronously, and then drive the liquid-filling needle to move vertically and vertically synchronously.

As shown in FIG. 2 and FIG. 5 , the detection system for chemiluminescence immunoreaction includes a photomultiplier tube 503 and a photometric hole 204 . When the cuvette containing the sample to be detected and the immunoreaction reagent passes through the photometric hole 204, the luminescent phenomenon generated by the immune reaction is detected by the photomultiplier tube 503, and then the corresponding data is transmitted to the data analysis system, thereby completing the detection of the chemiluminescent immune reaction. Detection analysis. The photomultiplier tube 503 is arranged on the base 210 of the chemiluminescence immunoassay analyzer body. The light measuring hole 204 is arranged on the back side plate of the light shield.

As shown in FIG. 2 and FIG. 3 , the body of the chemiluminescence immunoassay analyzer further includes a base 210 which is fixedly connected to the bottom plate of the housing of the chemiluminescence immunoassay analyzer. The fixing method of the two can be selected from one of connection methods such as threaded connection, buckle connection, rivet connection, welding, etc., preferably threaded connection. The base 210 is used to fix the moving mechanism of the reaction cup and the moving mechanism of the liquid filling needle, so as to ensure the stability and safety of the immune analyzer during operation.

As shown in FIG. 3 and FIG. 5 , the chemiluminescence immunoassay analyzer body also includes the above-mentioned light-shielding cover. The light shield surrounds the reaction cup moving mechanism, reaction cup 208, reaction cup support 209, liquid addition needle, liquid addition needle holder 205, and liquid addition needle movement mechanism from around and above. They can be fixedly connected together, and can be connected by threaded connection, buckle connection, rivet connection, welding and other connection methods, and threaded connection is preferably used. The light-shielding cover is fixed on the base 210 of the chemiluminescence immunoassay analyzer body, and further fixed on the bottom plate of the shell of the chemiluminescence immunoassay analyzer.

As shown in FIG. 3 , on the side wall of the light-shielding cover opposite to the first drive motor 201 and near the end of the cuvette holder 209 , there is a side door for the cuvette holder 209 to pass in and out of the light-shielding cover along the first slide rail 202 . A first side plate matching the shape of the side door is provided on the side door, and the first side plate is magnetically attracted to the edge of the side door, and the cuvette holder 209 and the first side plate can be connected together by magnetic force. When the cuvette holder 209 slid out of the side door of the light shield along the first slide rail 202, the first side plate would break away from the side door of the light shield under the push of the cuvette holder 209, and be adsorbed together with the cuvette holder 209, simultaneously Move towards the housing of the chemiluminescence immunoassay analyzer. On the side wall of the shell of the chemiluminescence immunoassay analyzer, a door 101 is arranged, and the edge of the door 101 is magnetically adsorbed with a second side plate matching the shape of the door 101, and the second side plate can also pass through the first side plate Magnetically stick together. When the cuvette support 209 and the first side plate slide out of the door 101 along the direction of the first slide rail 202, the cuvette support 209 pushes the first side plate and the second side plate to move out of the door 101 horizontally together. Place or replace cuvettes outside the housing of the luminescence immunoassay analyzer. When the cuvette holder 209 carries the cuvette and moves to the inside of the chemiluminescence immunoassay analyzer, after the cuvette holder 209 enters the casing, the second side plate is adsorbed on the edge of the door 101, and the door 101 is closed. The first side plate and the second side plate are separated from each other, and the cuvette holder 209 continues to move toward the inside of the chemiluminescence immunoassay analyzer. When the cuvette holder 209 moves to the side door on the light shield, the first side plate is adsorbed on the side door, The cuvette support 209 is separated from the first side plate, and the side door is closed to form a light-shielding space in the light-shielding cover. The cuvette holder 209 continues to move toward the inside of the light-shielding cover, and begins to perform immunoluminescence reaction and detection.

As shown in FIG. 5 , a circuit control panel 504 is provided on the back side of the light shield. After the external power is turned on, the operation of the chemiluminescence immunoassay analyzer can be controlled through the preset program stored in the circuit control panel 504 .

In order to facilitate the understanding of the technical solution of the present utility model, the following is an example of a detection experiment in which two reaction reagents (A and B) are added to a sample to be detected according to the successive steps to carry out the detection experiment of luminescence immunoreaction, and the operation method of the chemiluminescence immunoassay analyzer is provided, specifically Steps include:

1. Adding samples. First connect the external power supply through the power interface 103, and the circuit control panel 504 is powered on and running. Then press the switch button 102, the door 101 is opened, the first driving motor 201 is forwardly driven, and the first slide rail 202 is driven to move outside the chemiluminescence immunoassay analyzer, synchronously driving the first slider 203 and the cuvette holder 209 to slide to Chemiluminescence immunoassay analyzer outside. Then, the cuvette 208 is placed on the cuvette holder 209, and then 8 samples to be tested are added into the cuvette 208 according to the order of numbers from small to large.

Second, detection and analysis. Press the switch button 102 again, the first driving motor 201 reverses, drives the first sliding rail 202 to move into the chemiluminescence immunoassay analyzer, and synchronously drives the first slider 203, cuvette holder 209, and cuvette 208 to slide into the chemical chamber. Glow inside the immunoassay analyzer, then the side door closes. At the same time, the second driving motor 401 is running forward, driving the second slide rail 301 to move vertically upward, synchronously driving the second slider 303, the liquid filling needle holder 205 and the liquid filling needle to move vertically upward, so that the liquid filling needle outlet higher than the opening of the cuvette 208 . When the No. 1 cuvette moves below the second liquid addition needle 207, the second liquid addition pump 502 operates to add the reaction reagent A into the No. 1 cuvette to carry out the first chemical reaction. Then the first sliding rail 202 continues to slide, and when the No. 1 cuvette moves below the first liquid addition needle 206, the first liquid addition pump 501 operates, and the reaction reagent B is added to the No. 1 cuvette, and the second step is performed. chemical reaction. At the same time, the No. 2 reaction cup moves to the bottom of the No. 2 liquid addition needle, and the second liquid addition pump 502 operates to add the reagent A into the No. 2 reaction cup, and the first step of the chemical reaction is carried out in the No. 2 reaction cup. Then the first sliding rail 202 continues to slide, and when the No. 1 cuvette moves to the position of the light measuring hole 204, the photomultiplier tube 503 operates to detect the luminescence of the reactant in the No. 1 cuvette. At the same time, the No. 2 reaction cup moves to the bottom of the No. 1 liquid addition needle, the first liquid addition pump 501 operates, and the reaction reagent B is added into the No. 2 reaction cup, and the second chemical reaction is carried out in the No. 2 reaction cup. With the continuous movement of the first slide rail 202 driven by the first drive motor 201, the eight cuvettes are sequentially added with reagents A and B, and then moved to the photometric aperture 204, where the photomultiplier tubes detect the light emitted by the reactants in sequence, Until the detection of the eighth cuvette is completed. At the same time as the detection, the detection data is transmitted to the computer connected with the chemiluminescence immunoassay analyzer, and the data analysis is performed synchronously.

Three, shut down. First press the switch button 102, the chemiluminescence analyzer runs according to the preset program, first turn off the first filling pump 501 and the second filling pump 502, then the second driving motor 401 reverses, driving the second sliding rail 301 vertically Moving straight down drives the second slider 303 , the liquid-filling needle holder 205 , and the liquid-filling needle to move vertically downward synchronously. When the liquid-filling needle is reset, the second driving motor 401 stops running. Then the first driving motor 201 rotates forward, drives the first sliding rail 202 to move to the outside of the chemiluminescence immunoassay analyzer, and synchronously drives the first slider 203, cuvette holder 209, and cuvette 208 to move to the outside of the chemiluminescence immunoassay analyzer, When the cuvette 208 moves out of the bin door 101 , the first driving motor 201 stops running, and the operator removes the cuvette 208 from the cuvette holder 209 . Press the switch button 102 again, and the first drive motor 201 will move forward, driving the first sliding rail 202, the first slider 203, and the cuvette holder 209 to move into the chemiluminescence immunoassay analyzer. When the first slider 203 and the cuvette After the bracket 209 is reset, the first driving motor 201 stops running, and the warehouse door 101 is closed. The chemiluminescence immunoassay analyzer was powered off, and then the external power supply was disconnected.

The above is only an embodiment of the utility model, and does not limit the patent scope of the utility model. Any equivalent structure transformation made by the content of the specification of the utility model, or directly or indirectly used in other related technical fields, is the same as The theory is included in the patent protection scope of the present utility model.

Claims (10)

1. A chemiluminescent immunoassay analyzer for instant liquid addition and detection, comprising a housing and an analyzer body, characterized in that: the analyzer body includes: cuvette for chemiluminescence immunoreaction; A cuvette holder, used to fix the cuvette, a groove for holding the cuvette is arranged on the cuvette holder; a reaction cup moving mechanism, used to drive the reaction cup holder and the reaction cup to move in the horizontal direction, and the reaction cup moving mechanism is fixedly connected with the reaction cup holder; A liquid addition needle is used to add chemiluminescence immunoreaction reagents into the cuvette, the liquid addition needle is arranged above the cuvette moving mechanism, and the liquid addition needle can move up and down; The photomultiplier tube is used to detect the chemiluminescent immune reaction in the cuvette, and the photomultiplier tube is fixed on the bottom plate of the housing. 2. The chemiluminescence immunoassay analyzer according to claim 1, characterized in that: there are at least two cuvettes, and the cuvettes are arranged side by side. 3. The chemiluminescence immunoassay analyzer according to claim 1 or 2, characterized in that: there are at least two liquid addition needles, and the liquid addition needles are arranged side by side. 4 . The chemiluminescence immunoassay analyzer according to claim 3 , wherein the distance between two adjacent liquid filling needles is equal to the distance between two adjacent cuvettes. 5. The chemiluminescence immunoassay analyzer according to claim 1, characterized in that: the analyzer body also comprises: A filling pump, which is airtightly connected to the filling needle through a pipeline, and the filling pump is in one-to-one correspondence with the filling needle, the filling pump is fixed on the bottom plate of the housing, and the filling pump The pump can sequentially pump the chemiluminescence immunoreaction reagent into the liquid addition needle and the reaction cup. 6. The chemiluminescence immunoassay analyzer according to claim 1, characterized in that: positioning holes are set on the cuvette support, and positioning pins are set on the cuvette moving mechanism, through the positioning holes and the positioning pins The cooperation of the cuvette can accurately fix the cuvette holder on the cuvette moving mechanism. 7. The chemiluminescence immunoassay analyzer according to claim 6, characterized in that: the cuvette moving mechanism comprises: a first driving motor, which provides power for the horizontal movement of the cuvette holder; a first slide rail, which is connected to the first drive motor and can move in the horizontal direction; The first slider is fixedly connected with the first slide rail, the positioning pin is arranged on the first slider, and the first slider can move horizontally along the first slide rail. 8. The chemiluminescence immunoassay analyzer according to claim 1, characterized in that: the number of the grooves is greater than or equal to the number of the cuvettes. 9. The chemiluminescent immunoassay analyzer according to claim 8, wherein the grooves correspond to the cuvettes one by one. 10. The chemiluminescence immunoassay analyzer according to any one of claims 1-9, characterized in that: the analyzer body also includes a light-shielding cover, and the light-shielding cover covers the cuvette from around and above. surrounded by the moving mechanism, the cuvette, the cuvette support, the filling needle, the fixing seat of the filling needle and the moving mechanism of the filling needle, and the light-shielding cover is fixed on the bottom plate of the housing, A photometric hole for the photomultiplier tube to detect the chemiluminescent immune reaction is arranged on the light shield.

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