CN217120311U

CN217120311U - Trace liquid sampling device for pipette head

Info

Publication number: CN217120311U
Application number: CN202220166121.3U
Authority: CN
Inventors: 李东
Original assignee: Wuxi Boao Maya Medical Technology Co ltd
Current assignee: Chengdu Maya Lightyear Technology Co ltd; Wuxi Boao Maya Medical Technology Co ltd
Priority date: 2022-01-21
Filing date: 2022-01-21
Publication date: 2022-08-05
Anticipated expiration: 2032-01-21

Abstract

The utility model discloses a trace liquid sampling device for pipette tip, which comprises a pressure sampling plug, wherein the first end part of the pressure sampling plug is used for connecting a power source, the second end part is used for connecting the pipette tip of the trace pipette, at least two sealing rings are arranged in sequence on one side close to the second end part, and the total diameter of the sealing ring close to the second end part and the pressure sampling plug body is smaller; the trace liquid sampling device is provided with a plurality of sealing rings at one end of a pressure sampling plug, and the diameters of the sealing rings are different, so that the trace liquid sampling device can be compatible with pipette heads of various models; in addition, the symmetry characteristic of the liquid storage consumable is considered, the design of the coaxial plunger is adopted, the pressure is uniformly applied to the position above the liquid level, and the sample is injected downwards from the shaft center, so that all trace liquid can be ensured to be transferred directionally to the maximum extent.

Description

Trace liquid sampling device for pipette head

Technical Field

The utility model relates to a sample collection field, in particular to a trace liquid sampling device for liquid-transfering gun rifle head.

Background

In biochemical analysis instruments, point-of-care testing (POCT) reagent cartridges, and microfluidic diagnostic chips, it is often necessary to use a liquid collection and solution sampling device to transfer the relevant solutions to a detection and analysis system, where the liquids and solutions may include biological samples such as blood, sputum, urine, alveolar lavage fluid, etc., and pre-extracted nucleic acid samples, prepared reaction systems, biochemical reagents to be tested, etc., to form input samples for biochemical, immunological, or molecular detection and diagnosis. The sample is usually used in a small amount, for example, the sample suction amount of a traditional large-scale analyzer is 1-3 ml, while the sample amount of a novel POCT card box and a microfluidic chip is usually only 50-500 microliter, and a micro system only needs picoliter to nanoliter is partially applied.

The existing sample introduction device cannot be compatible with pipette tips of various models, and for the pipette tips of different models, sample transfer can be completed only by adopting sample introduction devices of different models, and cross infection is easily caused by frequent replacement of the sample introduction devices.

SUMMERY OF THE UTILITY MODEL

In order to solve the problem, the utility model provides a trace liquid sampling device that can be applicable to the liquid-transfering gun rifle head of multiple model and use.

In order to realize the purpose, the utility model provides a technical scheme is: the utility model provides a trace liquid sampling device for pipetting gun rifle head, advances the kind stopper including pressure, the first end of pressure advances the kind stopper is used for connecting the power supply, and the second end is used for connecting trace pipetting gun rifle head, is close to one side of second end has set gradually two at least sealing washers, is close to more the sealing washer of second end and the total diameter of pressure advance kind stopper body are littleer.

As a preferable technical scheme, one side of the pressure sample injection plug, which is close to the second end portion, is in a circular truncated cone shape, and the diameter of the pressure sample injection plug, which is closer to the second end portion, is smaller.

As a preferable technical solution, a side of the pressure sampling plug near the second end portion is stepped, and a diameter of the pressure sampling plug closer to the second end portion is smaller.

As a preferred technical scheme, one side of the pressure sampling plug, which is close to the second end, is provided with annular grooves corresponding to the number of the sealing rings, and the sealing rings are fixed in the grooves.

As a preferred technical scheme, the first end portion is provided with a pagoda head, the pagoda head is connected with one end of a hose, and the other end of the hose is connected with a power source.

As a preferred technical scheme, the height of the pagoda head is 2-5mm, and the conical surface is 6-30 degrees.

As a preferred technical solution, the seal ring is made of elastic rubber.

As a preferred technical scheme, the pressure sampling plug is provided with a through hole from the axle center of the first end part to the axle center of the second end part.

As a preferable technical scheme, the diameter of the through hole is 0.5-3 mm.

The utility model discloses beneficial effect for prior art is: the trace liquid sampling device is provided with a plurality of sealing rings at one end of a pressure sampling plug, and the diameters of the sealing rings are different, so that the trace liquid sampling device can be compatible with pipette heads of various models; in addition, the symmetry characteristic of the liquid storage consumable is considered, the design of the coaxial plunger is adopted, the pressure is uniformly applied to the position above the liquid level, the sample is fed downwards from the shaft center, and all trace liquid can be ensured to be transferred directionally to the maximum extent.

Drawings

FIG. 1 is an overall block diagram of an embodiment of the present invention;

fig. 2 is a usage state diagram of an embodiment of the present invention;

FIG. 3 is a longitudinal cross-sectional view of FIG. 2;

fig. 4 is an assembly view of an embodiment of the present invention;

fig. 5 is a state diagram of another embodiment of the present invention;

FIG. 6 is a longitudinal cross-sectional view of FIG. 5;

fig. 7 is an assembly view of another embodiment of the present invention;

fig. 8 is an overall structural view of another embodiment of the present invention;

fig. 9 is a state diagram of another embodiment of the present invention;

fig. 10 is a longitudinal sectional view of fig. 9.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

As used in this application and the appended claims, the terms "a," "an," "the," and/or "the" are not intended to be inclusive in the singular, but rather are intended to be inclusive in the plural unless the context clearly dictates otherwise. In general, the terms "comprises" and "comprising" merely indicate that steps and elements are included which are explicitly identified, that the steps and elements do not form an exclusive list, and that a method or apparatus may include other steps or elements.

The relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present application unless specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective portions shown in the drawings are not drawn in an actual proportional relationship for the convenience of description. Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.

It should be noted that the terms "first", "second", and the like are used to define the components, and are only used for convenience of distinguishing the corresponding components, and the terms have no special meanings unless otherwise stated, and therefore, the scope of protection of the present application is not to be construed as being limited. Further, although the terms used in the present application are selected from publicly known and used terms, some of the terms mentioned in the specification of the present application may be selected by the applicant at his or her discretion, the detailed meanings of which are described in relevant parts of the description herein. Further, it is required that the present application is understood not only by the actual terms used but also by the meaning of each term lying within.

Referring to fig. 1, the embodiment provides a micro liquid sampling device for a pipette tip, including a pressure sampling plug 11, one end of the pressure sampling plug 11 is a first end 111, the other end is a second end 114, through holes 110 are symmetrically formed from the first end 111 to the second end, the through holes 110 are used for medium flowing, the diameter of the through holes 110 is 0.5-3mm, in this embodiment, 1mm is adopted.

Further, the first end 111 is used for connecting a power source, in this embodiment, the power source is a precision adjustable pressure pump, and the pressure medium of the power source can be air or a solution incompatible with water.

Further, the second end 114 is configured to connect to a pipette tip of a conventional disposable pipette tip, including but not limited to 10uL, 20uL, 100uL, 200uL, and 1mL volume; preferably, 20uL, 200uL and 1mL volume micropipette gun tips are used herein.

In order to achieve the technical purpose of the present invention, a sealing ring 12 and a sealing ring 13 are sequentially disposed on a side close to the second end 114, and the total diameter of the sealing ring and the pressurized sampling plug body is smaller as the side close to the second end 114 is closer.

Referring to fig. 4, when the tip 21 of the small-sized micropipette gun is used, the tip 21 of the small-sized micropipette gun is attached to the seal ring 13, the seal ring 13 is deformed when the pressure sample introduction plug 11 is pressed into the tip 21 of the small-sized pipette gun, and the seal ring 12 is positioned outside the tip 21 and is not deformed when the pressure sample introduction plug 11 is pressed into the tip 21 of the small-sized pipette gun.

Referring to fig. 5 to 7, when another large-sized pipette tip 22 is used, the pipette tip 22 is attached to the packing 12, the packing 12 is deformed when the pressure sampling plug 11 is pressed into the pipette tip 22, and the packing 13 is positioned inside the pipette tip 22 without contact and is not deformed when the pressure sampling plug 11 is pressed into the large-sized pipette tip 22.

It should be noted that, although only two seal rings are provided in the present embodiment, the protection scope of the present invention is not limited thereto, and other numbers of seal rings, for example, three or four seal rings, are within the protection scope of the present invention.

In this embodiment, a side of the pressure sampling plug 11 close to the second end 114 is in a circular truncated cone shape, and a diameter of the pressure sampling plug 11 closer to the second end 114 is smaller, and is a tapered slope. The taper angle of the taper is consistent with the inclination of the inner wall of the pipette head, and the taper is attached to the inner wall of the pipette head after the sealing ring 12 or the sealing ring 13 deforms.

In other embodiments, the side of the pressure sample plug 11 near the second end 114 is stepped, and the diameter of the pressure sample plug 11 closer to the second end 114 is smaller.

In this embodiment, the side of the pressure sampling plug near the second end is provided with

annular grooves

112 and 113 corresponding to the number of the sealing rings, the sealing rings 12 are disposed in the grooves 112, and the sealing rings 13 are disposed in the grooves 113.

In other embodiments, the annular groove is not provided, and the second end 114 is directly covered with glue or other techniques, so as to achieve the technical effects of the present invention.

In this embodiment, the first end 111 is provided with a pagoda head having a height of 2-5mm and a taper of 6-30 degrees, and in this embodiment, a taper of 3.5mm and 15 degrees is used. The pagoda head is connected with one end of hose 13, and the power supply is connected to the other end of hose 13. The pressure applied via the hose 13 acts on the

pipette tips

21 and 22 and pushes the liquid inside them out continuously from the outlet at the lower end.

In this embodiment, the middle portion of the pressure sample injection plug 11 is provided with a diameter-variable portion 115, the diameter of the diameter-variable portion 115 is larger than the diameter of other regions, and the diameter-variable portion 115 is convenient for a worker or a mechanical device to clamp the sample injection device, so as to replace the pipette tip, in other embodiments, an anti-skid thread may be provided at the diameter-variable portion 115.

In another embodiment, referring to fig. 8 to 10, the middle of the pressure sampling plug 11 is not provided with a diameter-variable portion, and the other structure is not changed.

In addition, in the present embodiment, the

seal rings

12 and 13 are made of elastic rubber. It should be noted that the protection scope of the present invention is not limited thereto, and the sealing ring made of other materials, such as latex, resin, etc., having certain elasticity and sealing performance is within the protection scope of the present invention.

The trace liquid sampling device is provided with a plurality of sealing rings at one end of a pressure sampling plug, and the diameters of the sealing rings are different, so that the trace liquid sampling device can be compatible with pipette heads of various models; in addition, the symmetry characteristic of the liquid storage consumable is considered, the design of the coaxial plunger is adopted, pressure is applied to the position above the liquid level, and downward sample injection is carried out from the shaft center, so that all trace liquid can be ensured to be transferred directionally to the maximum extent.

The above-mentioned embodiment of the present invention is only, and not the scope of the patent of the present invention is limited, all the equivalent structures or equivalent processes made by the contents of the specification and the drawings are utilized, or directly or indirectly applied to other related technical fields, and all the same principles are included in the patent protection scope of the present invention.

Claims

1. The utility model provides a trace liquid sampling device for pipette rifle head, includes pressure advances kind stopper, its characterized in that: the first end of the pressure sampling plug is used for being connected with a power source, the second end of the pressure sampling plug is used for being connected with a pipette head of a micro-pipetting gun, at least two sealing rings are sequentially arranged on one side close to the second end, and the total diameter of the sealing rings close to the second end and the pressure sampling plug body is smaller.

2. The micro liquid sample introduction device according to claim 1, wherein: one side that the plug is advanced to pressure is close to the second tip is the round platform form, and is close to more the diameter that the plug was advanced to pressure of second tip is littleer.

3. The micro liquid sample introduction device according to claim 1, wherein: one side of the pressure sampling plug, which is close to the second end portion, is step-shaped, and the diameter of the pressure sampling plug, which is closer to the second end portion, is smaller.

4. A micro liquid sample introduction device according to any of claims 1 to 3, wherein: one side that the pressure advances kind stopper is close to the second end is provided with the annular groove corresponding with sealing washer quantity, the sealing washer is fixed in the recess.

5. The micro liquid sample introduction device according to claim 1, wherein: the first end part is provided with a pagoda head, the pagoda head is connected with one end of a hose, and the other end of the hose is connected with a power source; the pressure applied by the hose acts on the pipette tip and pushes the liquid in the pipette tip to continuously flow out of the outlet at the lower end part.

6. A micro liquid sample introduction device according to claim 5, wherein: the pagoda head is 2-5mm in height and 6-30 degrees in conical surface.

7. The micro liquid sample introduction device according to claim 1, wherein: the seal ring is made of elastic rubber.

8. The micro liquid sample introduction device according to claim 1, wherein: the pressure sample injection plug is provided with a through hole from the first end to the second end.

9. The micro liquid sample introduction device according to claim 8, wherein: the diameter of the through hole is 0.5-3 mm.