CN216361583U - Medicinal glass bottle small opening aperture measuring device - Google Patents

Abstract

The utility model discloses a device for measuring the aperture of a leak hole of a medicinal glass bottle, which comprises: the test cavity is used for placing an external medicinal glass bottle; the detection module is connected with the test cavity and the medicinal glass bottle and is used for detecting the medicinal glass bottle. According to the utility model, by adopting the vacuum technology theory, the size of the aperture of the leak hole is calculated by using the measured values of the gas flow, the upstream pressure, the downstream pressure and the gas temperature collected by the color paperless recorder, and the measured result data is more accurate.

Description

Pharmaceutical glass bottle leak hole diameter measuring device

technical field

The utility model relates to the technical field of testing devices, in particular to a device for measuring the leak hole diameter of a medicinal glass bottle.

Background technique

Pharmaceutical glass bottles are mainly used for pharmaceutical storage, and their sealing integrity prevents loss of contents, intrusion of microorganisms, and ingress of gases or other substances. At present, the main methods for testing the sealing integrity of pharmaceutical glass bottles are the microbial challenge method and the color water method. Both of the above two methods require a standard leak with a standard pore size value to verify the detection limit of the method. Therefore, it is of great significance to accurately measure the pore size of the leak of medicinal glass bottles.

At present, the methods for measuring micron-scale leaks at home and abroad mainly include optical detection method and differential pressure gas flow detection method. Among them, the optical detection method uses a high-magnification microscope to observe the leak hole, and measure the size of cracks and leak holes. Due to the irregular shape of cracks or leaks, it is difficult to calculate the leakage area, and since the sizes of cracks and leaks are micrometers, it is difficult to measure. Therefore, using the optical detection method to evaluate the aperture result of the leak hole has a large error. The differential pressure gas flow detection method adopts the principle that a pressure difference is formed between the upstream and downstream of the leak after the gas passes through the leak. It is deduced according to the theory of vacuum technology. value to calculate the equivalent pore size value of the leak. Therefore, in the practical application of sealing detection of medicinal glass bottles, the pressure-difference gas flow detection method based on the principle of pressure decay is economical and feasible to detect the sealing of medicinal glass bottles, and has important practical value.

Utility model content

According to an embodiment of the present utility model, a device for measuring the leak hole diameter of a medicinal glass bottle is provided, comprising:

Test cavity for placing external medicinal glass bottles;

The detection module is connected with the test cavity and the medicinal glass bottle, and is used for detecting the medicinal glass bottle.

Further, the detection module includes:

Sealing stopper, which is sealed at the mouth of the medicinal glass bottle;

a first trachea, one end of the first trachea is inserted into the glass bottle through the sealing plug, and the other end of the first trachea is communicated with the outside world;

a detection component, the detection component is connected to the first trachea and the test cavity;

The vacuuming assembly is connected with the test cavity, and is used for extracting the internal gas of the test cavity.

Further, the detection component includes:

a first pressure transmitter, which is connected to the first gas pipe and used to measure the internal gas pressure of the medicinal glass bottle;

a temperature transmitter, the temperature transmitter is connected to the first gas pipe and is located on one side of the first pressure transmitter, and is used for measuring the internal gas temperature of the first gas pipe;

a flowmeter, which is connected to the first gas pipe and is used to measure the gas flow rate leaked from the leak of the medicinal glass bottle;

a second pressure transmitter, which is communicated with the interior of the test cavity and used to measure the internal gas pressure of the test cavity;

The paperless recorder is connected with the first pressure transmitter, the temperature transmitter, the flow meter and the second pressure transmitter.

Further, the vacuuming assembly includes:

a second trachea, one end of the second trachea is communicated with the test cavity;

a control valve, which is arranged on the second trachea;

The vacuum pump is connected with the other end of the second gas pipe.

Further, the first trachea and the second trachea are both PU pipes.

According to the device for measuring the leak hole diameter of the medicinal glass bottle according to the embodiment of the present invention, the leak hole diameter is calculated from the measured values of the gas flow rate, upstream pressure, downstream pressure and gas temperature collected by the color paperless recorder through the vacuum technology theory, The measured result data is more accurate.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and are intended to provide further explanation of the claimed technology.

Description of drawings

FIG. 1 is a schematic structural diagram of a device for measuring the leak hole diameter of a medicinal glass bottle according to an embodiment of the present invention.

Detailed ways

The preferred embodiments of the present utility model will be described in detail below with reference to the accompanying drawings, and the present utility model will be further elaborated.

First, the device for measuring the leak hole diameter of a medicinal glass bottle according to an embodiment of the present invention will be described with reference to FIG. 1, which is used to detect the diameter of the leak hole 31 of the medicinal glass bottle 3, and can also be used to detect the leak of other similar glass bottles. The diameter of the hole 31 is not limited to the diameter of the leak hole 31 of the medicinal glass bottle 3, and its application scenarios are very wide.

As shown in FIG. 1 , the device for measuring the leak hole diameter of a medicinal glass bottle according to an embodiment of the present invention has a test cavity 1 and a detection module.

Specifically, as shown in FIG. 1 , in this embodiment, the test cavity 1 is used to place the external medicinal glass bottle 3 . In the test cavity 1 , the inner and outer parts of the medicinal glass bottle 3 only pass through the medicinal glass The leak hole 31 of the bottle body of the bottle 3 is connected; the detection module is connected to the test cavity 1 and the medicinal glass bottle 3 , and is used to detect and calculate the relevant data of the aperture diameter of the leak hole 31 of the medicinal glass bottle 3 .

Further, as shown in FIG. 1 , in this embodiment, the detection module includes: a sealing plug 21 , a first gas pipe 22 , a detection component and a vacuuming component. The sealing plug 21 is sealed on the bottle mouth of the medicinal glass bottle 3, and the sealing plug 21 is used to seal the glass bottle mouth; one end of the first air tube 22 is inserted into the interior of the glass bottle through the sealing plug 21, and the other end of the first air tube 22 is The outside is connected, and the first gas pipe 22 is used for the circulation of the gas inside the glass bottle and the outside gas; the detection component is connected to the first gas pipe 22 and the test cavity 1, and the detection component is used for detecting and calculating the relevant data of the aperture of the leak hole 31 of the medicinal glass bottle 3; The vacuuming assembly is connected to the test chamber 1 for extracting the internal gas of the test chamber 1 .

Further, as shown in FIG. 1 , in this embodiment, the detection component includes: a first pressure transmitter 231 , a temperature transmitter 232 , a flow meter 233 , a second pressure transmitter 234 and a paperless recorder 235 . The first pressure transmitter 231 is connected to the first gas pipe 22 for measuring the internal gas pressure of the medicinal glass bottle 3, that is, the upstream pressure of the leak hole 31; the temperature transmitter 232 is connected to the first gas pipe 22 and is located at the first pressure One side of the transmitter 231 is used to measure the internal gas temperature of the first gas pipe 22; the flow meter 233 is connected to the first gas pipe 22, and the flow meter 233 adopts a low pressure loss flow meter 233, which is used to measure the temperature of the medicinal glass bottle 3. The gas flow rate leaked from the leak hole 31; the second pressure transmitter 234 communicates with the interior of the test chamber 1, and is used to measure the internal gas pressure of the test chamber 1, that is, the downstream pressure of the leak hole 31; the paperless recorder 235 is connected to the first A pressure transmitter 231, a temperature transmitter 232, a flow meter 233 and a second pressure transmitter 234 are connected, and the paperless recorder 235 adopts a color paperless recorder 235, which is more convenient for observation and use, and the paperless recorder 235 is used for It is used to collect data measurement values of the first pressure transmitter 231 , the temperature transmitter 232 , the flow meter 233 , and the second pressure transmitter 234 .

Further, as shown in FIG. 1 , in this embodiment, the vacuuming component includes: a second gas pipe 241 , a control valve 242 and a vacuum pump 243 . One end of the second air pipe 241 communicates with the test chamber 1 ; a control valve 242 is arranged on the second air pipe 241 to control the on-off of the second air pipe 241 ; the vacuum pump 243 is connected to the other end of the second air pipe 241 . The vacuum pump 243 is used to extract the gas in the test cavity 1 through the second air pipe 241 , to reduce the air pressure in the test cavity 1 , and to form a pressure difference between the inside and the outside of the medicinal glass bottle 3 .

Further, as shown in FIG. 1, in this embodiment, the first air pipe 22 and the second air pipe 241 are both PU pipes, which have good chemical corrosion resistance, light weight, high wear resistance, anti-staining, anti-flatulence, etc. performance.

When in use, the gas in the test chamber 1 is extracted by the vacuum pump 243, the air pressure in the test chamber 1 is reduced, and a pressure difference is formed between the inside and the outside of the medicinal glass bottle 3, so that the gas flows between the first trachea 22 and the second The second gas pipe 241 flows through the first pressure transmitter 231 to measure the internal gas pressure of the medicinal glass bottle 3 , that is, the upstream pressure of the leak hole 31 , the temperature transmitter 232 to measure the internal gas temperature of the first gas pipe 22 , and the flow rate. The meter 233 measures the gas flow rate leaked from the leak hole 31 of the medicinal glass bottle 3 and measures the internal gas pressure of the test cavity 1 through the second pressure transmitter 234 , that is, the downstream pressure of the leak hole 31 , and then collects the data through the paperless recorder 235 . The data measurement values of the first pressure transmitter 231 , the temperature transmitter 232 , the flow meter 233 , and the second pressure transmitter 234 are used to calculate the aperture size of the leak hole 31 according to the theory of vacuum technology.

The above, with reference to FIG. 1 , the device for measuring the leak hole diameter of a medicinal glass bottle according to an embodiment of the present invention has been described. Through the vacuum technology theory, the gas flow rate, upstream pressure, downstream pressure, and gas temperature collected by the color paperless recorder 235 The measured value calculates the pore size of the leak hole 31, and the measured result data is more accurate.

It should be noted that, in this specification, the terms "comprising", "comprising" or any other variation thereof are intended to encompass non-exclusive inclusion, such that a process, method, article or device comprising a series of elements includes not only those elements , but also other elements not expressly listed or inherent to such a process, method, article or apparatus. Without further limitation, an element defined by the phrase "comprising" does not preclude the presence of additional identical elements in a process, method, article, or device that includes the element.

Although the content of the present invention has been described in detail through the above preferred embodiments, it should be appreciated that the above description should not be construed as limiting the present invention. Various modifications and substitutions to the present invention will be apparent to those skilled in the art after reading the foregoing. Therefore, the protection scope of the present invention should be defined by the appended claims.

Claims (5)

1. The utility model provides a medicinal glass bottle small opening aperture measuring device which characterized in that contains:

the test cavity is used for placing an external medicinal glass bottle;

the detection module is connected with the test cavity and the medicinal glass bottle and is used for detecting the medicinal glass bottle.

2. The apparatus for measuring a leak hole diameter of a pharmaceutical glass bottle according to claim 1, wherein the detection module comprises:

the sealing plug is sealed at the bottle opening of the medicinal glass bottle;

one end of the first air pipe penetrates through the sealing plug and is inserted into the glass bottle, and the other end of the first air pipe is communicated with the outside;

the detection assembly is connected with the first air pipe and the test cavity;

and the vacuumizing assembly is connected with the testing cavity and used for extracting the internal gas of the testing cavity.

3. The apparatus for measuring a leak hole diameter of a medicinal glass bottle according to claim 2, wherein the detecting unit comprises:

the first pressure transmitter is connected with the first air pipe and is used for measuring the internal gas pressure of the medicinal glass bottle;

the temperature transmitter is connected with the first air pipe, is positioned on one side of the first pressure transmitter and is used for measuring the internal gas temperature of the first air pipe;

the flowmeter is communicated with the first air pipe and is used for measuring the gas flow leaked from the leakage hole of the medicinal glass bottle;

the second pressure transmitter is communicated with the inside of the testing cavity and is used for measuring the internal gas pressure of the testing cavity;

and the paperless recorder is connected with the first pressure transmitter, the temperature transmitter, the flowmeter and the second pressure transmitter.

4. A glass pharmaceutical vial leak orifice diameter measuring device as defined in claim 3, wherein said vacuum pumping assembly comprises:

one end of the second air pipe is communicated with the testing cavity;

a control valve disposed on the second air pipe;

and the vacuum pump is connected with the other end of the second air pipe.

5. The apparatus for measuring the diameter of a leak hole of a medicinal glass bottle as defined in claim 4, wherein the first gas pipe and the second gas pipe are both PU pipes.

Images