CN216258517U

CN216258517U - Peritoneal dialysis system based on variable pressure

Info

Publication number: CN216258517U
Application number: CN202121199615.3U
Authority: CN
Inventors: 潘力; 马健东
Original assignee: VR Medical Technology Co Ltd
Current assignee: VR Medical Technology Co Ltd
Priority date: 2021-05-31
Filing date: 2021-05-31
Publication date: 2022-04-12
Anticipated expiration: 2031-05-31

Abstract

The utility model relates to the technical field of peritoneal dialysis, and discloses a peritoneal dialysis system based on variable pressure, which comprises: the height of the liquid supply bag from the ground is L1, and the height of the liquid supply bag from the ground is L2; at least one waste liquid collection device; at least one liquid supply pipeline for guiding the dialysate of the liquid supply bag into the abdominal cavity of the human body, wherein the power is provided by the height difference between L1 and L2; at least one negative pressure generating unit; at least one drainage pipeline for guiding the waste liquid in the abdominal cavity of the human body to a waste liquid collecting device/waste liquid bag; at least one fluid distribution system controls the flow rate of liquid in the liquid supply line and/or the drainage line by controlling the L1, the L2 and/or the negative pressure generating unit. By adopting the peritoneal dialysis system, the flow can be accurately controlled, the waste liquid in the abdominal cavity of a human body can be completely emptied, and the peritoneal dialysis system is simple in structure, silent and low in energy consumption.

Description

Peritoneal dialysis system based on variable pressure

Technical Field

The utility model relates to the technical field of peritoneal dialysis equipment, in particular to a peritoneal dialysis system based on variable pressure.

Background

Peritoneal Dialysis (PD) is to regularly and regularly inject prepared dialysate into the peritoneal cavity of a patient through a catheter by utilizing the characteristic that the peritoneum is used as a semi-permeable membrane, and because the concentration gradient difference of solutes exists at two sides of the peritoneum, the solute at one side with high concentration moves to the other side with low concentration (diffusion effect); the water moves from the hypotonic side to the hypertonic side (osmosis). The peritoneal dialysis solution is continuously replaced to achieve the purposes of removing in vivo metabolites and toxic substances and correcting water and electrolyte balance disorder. Most of peritoneal dialysis (peritoneal dialysis for short) patients in China are ambulatory continuous peritoneal dialysis (CAPD) patients. CAPD requires 3-4 exchanges of peritoneal dialysis fluid daily, which seriously affects the normal working life of the patient.

With the continuous improvement of the economic level of China and the pursuit of the freedom of life of patients, the selection of more expensive Automatic Peritoneal Dialysis (APD) treatment becomes a new trend. APD broadly refers to all treatments performed by automated machines instead of manually performing a peritoneal dialysis procedure. It can be divided into 4 modes of Nighttime Intermittent Peritoneal Dialysis (NIPD), Intermittent Peritoneal Dialysis (IPD), Continuous Cycle Peritoneal Dialysis (CCPD) and Tidal Peritoneal Dialysis (TPD). Among these 4 modes, NIPD is performed only at night, the patient is in a dry abdominal state during the day, the number of dialysis connection operations is minimized, and the degree of freedom provided to the patient is maximized, which is the most common APD mode.

The present invention relates to an improved Automated Peritoneal Dialysis (APD) system for clinical treatment including parenteral fluid administration in peritoneal dialysis, which is suitable for patients with acute renal failure, patients with chronic renal failure, patients with acute drug poisoning and patients with severe edema, water poisoning and heart failure due to any cause, etc.

Currently, there are two types of peritoneal dialysis apparatuses known, a powered peritoneal dialysis machine and a gravity type peritoneal dialysis machine. Wherein, the power type peritoneal dialysis machine utilizes a power method to convey the peritoneal dialysis solution to the peritoneal dialysis machine, the peritoneal dialysis solution is heated by the peritoneal dialysis machine and conveyed to the abdominal cavity of a patient, and the peritoneal dialysis solution is drained into a waste liquid device after the peritoneal dialysis solution is subjected to retention and dialysis exchange.

Gravity type peritoneal dialysis machine utilizes gravity method, and liquid is by the characteristic that the height flows to low, realizes that peritoneal dialysis liquid flows to the peritoneal dialysis machine from the high point, irritates into patient's peritoneal cavity through the heating of peritoneal dialysis machine, through the mode of remaining drainage in the waste liquid collection device behind the peritoneal dialysis.

However, the conventional power peritoneal dialysis machine and gravity peritoneal dialysis machine have the following problems:

the existing gravity type peritoneal dialysis machine is not beneficial to fully discharging dialysate in an abdominal cavity by only depending on height difference for drainage;

a second, prior art powered peritoneal dialysis machine employs at least one pump that is hydraulically operated to accomplish the inflow of fluid to, or the outflow of fluid from, the patient's peritoneal cavity. That is, in the conventional power type peritoneal dialysis machine, the liquid pump works continuously, and the power generated by the pump participates in the process of the whole liquid flowing into the abdominal cavity of the patient and also participates in the process of the whole liquid flowing out of the abdominal cavity of the patient.

Automated Peritoneal Dialysis (APD) therapy is often performed at night, and the operation of the pump can produce noise that can affect the rest of the patient. Moreover, the pump works continuously, and the energy consumption is higher.

Thirdly, the method comprises the following steps: the existing power peritoneal dialysis machine has the defects that when liquid is injected and waste liquid is drained, the instantaneous pressure is high, and the discomfort or pain of a patient is easily caused.

Fourthly: the existing power type peritoneal dialysis machine and the gravity type peritoneal dialysis machine have large volume and are inconvenient to carry.

SUMMERY OF THE UTILITY MODEL

The technical problem to be solved by the utility model is to provide a peritoneal dialysis system based on variable pressure, which can realize accurate control of flow, ensure that waste liquid in the abdominal cavity of a human body can be thoroughly emptied, and has the advantages of simple structure, silence and low energy consumption.

The technical problem to be solved by the present invention is to provide a peritoneal dialysis system based on variable pressure, which is portable and small in size.

In order to achieve the above technical effects, the present invention provides a peritoneal dialysis system based on variable pressure, comprising:

at least one liquid supply bag for supplying dialysate to the abdominal cavity of the human body, wherein the height of the liquid supply bag from the ground is L1, the height of the abdominal cavity of the human body from the ground is L2, and a height difference is formed between L1 and L2;

at least one waste liquid collecting device for receiving waste liquid discharged from the abdominal cavity of the human body, wherein the height of the waste liquid collecting device from the ground is L4, and a height difference is formed between L2 and L4;

at least one liquid supply pipeline for guiding the dialysate of the liquid supply bag into the abdominal cavity of the human body, wherein the power is provided by the height difference between L1 and L2;

at least one negative pressure generating unit;

and the power of the drainage pipeline is provided by the initial negative pressure provided by the negative pressure generating unit to the drainage pipeline and/or the height difference between the L2 and the L4.

As an improvement of the scheme, the device also comprises at least one fluid distribution system, and the fluid distribution system is connected with the liquid supply pipeline and the drainage pipeline so as to control the flow of liquid in the liquid supply pipeline and/or the drainage pipeline.

As a modification of the above scheme, the negative pressure generating unit provides intermittent negative pressure or continuous negative pressure, and the pressure provided by the negative pressure generating unit is variable;

the negative pressure provided by the negative pressure generating unit is 0-10 KPa.

As an improvement of the scheme, the negative pressure generating unit comprises a negative pressure cavity and a negative pressure generator connected with the negative pressure cavity, and the negative pressure cavity is arranged on the drainage pipeline.

As an improvement of the above scheme, the negative pressure generator comprises a shell, wherein the shell is provided with an air inlet and an air outlet, and a negative pressure pump, a water filtering valve and a pressure release valve are arranged in the shell;

the negative pressure cavity is connected with an air inlet of the negative pressure generator through a negative pressure interface end so as to apply variable negative pressure to the negative pressure cavity.

As an improvement of the above, the peritoneal dialysis system further comprises:

a supplement pouch for supplementing dialysate, the supplement pouch having a height of L3 from the ground;

a final sachet for providing an indwelling dialysate within the abdominal cavity of the human body, said final sachet being at a height L3 from the ground;

one or more of the L1, L2, L3 is height adjustable.

As an improvement of the scheme, the liquid supply pipeline and the drainage tube are provided by a consumable box.

As an improvement of the above, the consumable cartridge comprises:

a body end pipeline for connecting with the abdominal cavity of the human body;

a drainage pipeline for connecting with the waste liquid collecting device;

a liquid supply pipeline for connecting the liquid supply bag;

a supplement pipeline connected with the supplement medicine bag;

a last tubing for connection to a last fluid bag;

the body end pipeline, the drainage pipeline, the liquid supply pipeline, the supplement pipeline and the last pipeline are arranged side by side and connected through medical pipe clamps to form an intercommunicating pipeline;

the height of the consumable box from the ground is L5, and the height of the L5 is adjustable.

As an improvement of the above scheme, the method further comprises the following steps:

the first weighing unit is used for weighing the real-time weight of the liquid supply bag;

the first heating unit is used for heating the liquid supply bag;

a second weighing unit for weighing the real-time weight of the waste liquid collection device.

As an improvement of the scheme, the dialysis machine further comprises a positive pressure generating unit, wherein the positive pressure generating unit is a liquid bag extruding device and is used for extruding the liquid bag and providing positive pressure for injecting dialysate into the liquid bag.

The implementation of the utility model has the following beneficial effects:

the peritoneal dialysis system of the utility model comprises a liquid supply bag, a liquid outlet pipe and a liquid outlet pipe, wherein the power for leading dialysate of the liquid supply bag into the human abdominal cavity is provided by the height difference between L1 and L2, namely, the dialysate is injected into the human abdominal cavity from the liquid supply bag by using gravity; and the power that waste liquid collection device was derived to human abdominal cavity's waste liquid is then provided by initial negative pressure drive and the difference in height between human abdominal cavity and the waste liquid collection device, promptly, gives an initial negative pressure as the drive, when treating that whole drainage pipeline is full of liquid, abdominal cavity built-in pipeline and drainage pipeline, waste liquid collection device are linked together, can stop power this moment, makes abdominal cavity's liquid pass through in the drainage pipeline constantly drains waste liquid collection device.

Therefore, the utility model provides a peritoneal dialysis system with a brand new working mode, which combines the advantages of gravity type peritoneal dialysis and dynamic type peritoneal dialysis, realizes the injection of dialysate by utilizing gravity, realizes the drainage of waste liquid by utilizing power, ensures that the power does not participate in the whole drainage process, ensures that the power intervenes intermittently only when needed, has simple structure, effectively reduces the energy consumption of products and is quieter.

The peritoneal dialysis device is provided with a fluid distribution system, the flow of liquid in the liquid supply pipeline and/or the drainage pipeline is controlled through the change of the height difference and the change of the negative pressure (the size and the duration of the negative pressure generation) by controlling the L1, the L2 and/or the negative pressure generation unit, so that the accurate control of the flow can be realized, the whole process of injecting and discharging the fluid is mainly carried out by gravity, the negative pressure is only started initially, the whole process is stable and quiet, the peritoneal dialysis experience of a patient can be greatly improved, the problem that the waste liquid in the abdominal cavity of a human body cannot be completely emptied can be solved by the negative pressure, and discomfort and pain cannot be caused in the emptying process due to controllable pressure.

Thirdly, the peritoneal dialysis system of the utility model can realize various therapies of automatic peritoneal dialysis, including CCPD, IPD, TPD and the like. The peritoneal dialysis system enables the prescription of dialysis treatment to have greater flexibility, can individually set the injection liquid amount and the waste liquid amount discharged, timely adjusts the dialysis liquid amount suitable for the treatment requirements of patients, enables the patients to automatically exchange peritoneal dialysis liquid during sleeping, and can perform corresponding adjustment of treatment according to the peritoneal capacity and peritoneal functions of the patients, thereby achieving sufficient dialysis and improving the life quality of patients.

The utility model can simplify the structure, reduce the equipment volume and particularly simplify the structure of the consumable box.

Drawings

FIG. 1 is a schematic perspective view of a peritoneal dialysis system of the present invention;

FIG. 2 is a front view of the peritoneal dialysis system of the present invention;

FIG. 3 is a schematic view of a prior art drainage curve;

FIG. 4 is a schematic view of the drainage curve of the present invention;

FIG. 5 is a schematic diagram of an exploded view of an APD host according to the present invention;

FIG. 6 is a schematic view of the construction of the consumable cartridge of the present invention;

FIG. 7 is a schematic view of an exploded structure of the consumable cartridge of the present invention;

FIG. 8 is a schematic structural view of the negative pressure generator of the present invention;

FIG. 9 is a cross-sectional view of the negative pressure generator of the present invention;

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail below.

Referring to fig. 1, the present invention provides a variable pressure-based peritoneal dialysis system comprising:

at least one liquid supply bag 1 for supplying dialysate to the human abdominal cavity 2, wherein the height of the liquid supply bag 1 from the ground is L1, the height of the human abdominal cavity 2 from the ground is L2, the height difference between L1 and L2 is L1 > L2;

at least one waste liquid collecting device 3 for receiving waste liquid discharged from the human abdominal cavity 2, wherein the height of the waste liquid collecting device from the ground is L4, and a height difference is formed between L2 and L4;

at least one liquid supply pipeline 10 for guiding the dialysate of the liquid supply bag 1 into the abdominal cavity 2 of the human body, wherein the power is provided by the height difference between L1 and L2;

at least one negative pressure generating unit 4 providing an initial negative pressure drive to the drainage line 20;

at least one drainage pipeline 20 for guiding the waste liquid in the abdominal cavity 2 of the human body out to the waste liquid collecting device 3, wherein the power is provided by the initial negative pressure provided by the negative pressure generating unit to the drainage pipeline and/or the height difference between L2 and L4;

the peritoneal dialysis system of the utility model, wherein, the power for guiding the dialysate of the liquid supply bag 1 into the human abdominal cavity 2 is provided by the height difference between L1 and L2, L1 > L2, i.e. the infusion of the dialysate from the liquid supply bag into the human abdominal cavity is completed by gravity, and more preferably, the power for guiding the dialysate of the liquid supply bag 1 into the human abdominal cavity 2 is provided by the height difference between L1 and L2 and/or additional power;

the power for leading the waste liquid in the human abdominal cavity 2 to the waste liquid collecting device 3 is provided by the initial negative pressure drive. At this time, the dialysate of the liquid supply bag 1 can flow through the consumable box and then enter the abdominal cavity of the human body, and can also be directly injected into the abdominal cavity of the human body (at this time, the utility model is not provided with the consumable box); the waste liquid in the human abdominal cavity 2 can flow through the consumable box and then be guided out to the waste liquid collecting device 3, or can be directly guided out to the waste liquid collecting device 3 (at this time, the consumable box is not arranged in the utility model).

Normally, there is the difference in height between human abdominal cavity 2 and waste liquid collection device 3, and human abdominal cavity lies flat in bed, and human abdominal cavity 2 is apart from the height on ground for L2, and waste liquid collection device places in ground, and waste liquid collection device is apart from the height on ground for L4, have the difference in height between L2 and L4, and L2 > L4, and the power that waste liquid in human abdominal cavity was derived to waste liquid collection device is preferably provided by the difference in height between L2 and L4 and initial negative pressure jointly.

The drainage pipeline is communicated with the drainage pipeline and the waste liquid collecting device, the power can be stopped at the moment, the negative pressure cavity can provide continuous negative pressure, or the liquid in the abdominal cavity is continuously drained into the waste liquid collecting device through the drainage pipeline by utilizing the siphon principle. It should be noted that the negative pressure generating unit of the present invention provides an initial negative pressure driving, that is, the negative pressure only has a driving effect and does not need to exist continuously.

Preferably, the present invention further provides at least one fluid distribution system for controlling the flow rate of the liquid in the liquid supply line 10 and/or the drainage line 20 by controlling the L1, the L2 and/or the negative pressure generating unit 4. The fluid distribution system may be implemented by a control system built into the APD mainframe 5.

Preferably, the negative pressure generating unit 4 provides intermittent negative pressure or continuous negative pressure, and the pressure provided by the negative pressure generating unit is variable. The negative pressure provided by the negative pressure generating unit 4 is preferably 0-10KPa, more preferably 0-8 KPa, and specifically may be 1KPa, 2KPa, 3KPa, 4KPa, 5KPa, 6KPa, and 7KPa, but is not limited thereto. The negative pressure generating unit 4 controls the time of generating the negative pressure, the magnitude of the negative pressure and the duration time of the negative pressure, and controls the flow speed of the liquid in the drainage pipeline through the change of the negative pressure.

Furthermore, the utility model controls the flow rate of the liquid in the liquid supply pipeline 10 and/or the drainage pipeline 20 by controlling the L1, the L2 and/or the negative pressure generating unit and the change of the height difference and the change of the negative pressure, thereby realizing the accurate control of the flow rate, and the flow rate accuracy is less than or equal to 50 ml.

Preferably, the flow rate of the dialysate of the liquid supply bag introduced into the abdominal cavity of the human body is v₁The height difference between L1 and L2 is Δ L1, v₁Controlled in the range of (1-3) delta L1+ (60-100). Specifically, the inner diameter of the liquid supply pipeline is 2-10mm, the Delta L1 is more than or equal to 20cm and less than or equal to 60cm, and v is₁Is 80 to 250 ml/min. v. of₁The liquid drainage device is arranged in the range, so that when liquid is injected into the abdominal cavity of a human body, the human body can feel comfortable and efficient, and the liquid drainage device is favorable for thoroughly draining waste liquid in the abdominal cavity of the human body. If v is₁If the concentration is more than 250ml/min, impact force can be generated on the abdominal cavity, and abdominal pain is caused; if v is₁Less than 80ml/min, the time required for injection is prolonged, and the time for leaving the abdomen is shortened under the condition of the same treatment time, which is not beneficial to the complete emptying of the waste liquid of the human body. Furthermore, the utility modelPreferably, v₁Is 140 to 250 ml/min.

The flow velocity of the waste liquid of the abdominal cavity of the human body led out to the waste liquid collecting device is v₂，v ₂5 to 250 ml/min. If v is₂If the flow rate is more than 250ml/min, the drainage speed is too high, and the abdominal pain is easy to cause. If v is₂Less than 5ml/min, long treatment period, low treatment efficiency, and reduced number of cycles for the same treatment period. Preferably, v₂Is 100-220 ml/min. More preferably, v₂Is 150-200 ml/min.

In addition, the drainage speed is related to the residual liquid in the abdominal cavity in addition to the suction pressure, because the internal structure of the human abdominal cavity is complicated, when 20% of the liquid in the human abdominal cavity is remained, the drainage speed is reduced, which is a normal phenomenon.

According to the utility model, a consumable box can be arranged or not, and the negative pressure generating unit 4 can be arranged at the drainage pipeline in various ways. The height of the consumable box 6 from the ground is L5, and the height of the L5 is adjustable.

Preferably, when the drainage pipeline comprises the consumable box 6, the height of the consumable box 6 from the ground is L5, the abdominal cavity liquid is firstly sucked into the consumable box by using power (power type principle), the gravity of L5-L2 is overcome by using the power, and when the whole drainage pipeline 20 is filled with the liquid, the abdominal cavity built-in pipeline is communicated with the drainage pipeline 20 and the waste liquid collecting device 3. At this time, the power is stopped, and the liquid in the abdominal cavity is continuously drained to the waste liquid collecting device 3 through the drainage pipeline 20 by using the siphon principle. In use, the consumable cartridge 6 is placed in the APD mainframe 5.

A conventional power-type drainage curve is generally shown in fig. 3, which is first drawn from the abdominal cavity position of L2 to the consumable cartridge position of L5, and then drained to the waste collection device of L4. The APD of the peritoneal dialysis system of the utility model has a dynamic drainage curve as shown in figure 4, and the height L5 of the consumable box is adjusted to ensure that the L5 is adjusted to be consistent or basically consistent with the position of the abdominal cavity of the L2 and then is drained to the waste liquid collecting device of the L4, so that the drainage becomes simpler and smoother.

The height difference between L5 and L1 and L2 can be used to adjust the injection flow of the dialysate. The height difference between L5 and L2 and L4 can adjust the discharge flow rate of waste liquid.

The negative pressure generated by the negative pressure generating unit is preferably-40 mmHg to-80 mmHg, namely-5.3 to-10.7 KPa according to the L2 height and the L5 height which are set by people habitually. At the moment, the smooth work of the peritoneal dialysis system can be ensured, and the abdominal cavity pressure of the human body is in accordance with the regulation of law.

As a more preferred embodiment of the present invention, referring to fig. 1 and 2, the present invention further comprises a supplement pouch 7 for supplementing dialysate, and a final pouch 8 for providing dialysate to be retained in the abdominal cavity of a human body.

As shown in FIG. 2, liquid supply bag 1 is at a height of L1 from the ground, human abdominal cavity 2 is at a height of L2 from the ground, supplemental pouch 7 is at a height of L3 from the ground, last pouch 8 is at a height of L3 from the ground, and waste liquid collecting device is at a height of L4 from the ground.

The height difference between L3 and L1 is L3 > L1, and the dialysate is supplemented by controlling the height difference between L3 and L1. Meanwhile, the last liquid medicine is replenished by controlling the height difference between L3 and L1.

Preferably, one or more of the L1, L2, L3 is height adjustable, and the L4 is fixed or adjustable in height. Preferably, the heights of the L1, the L2 and the L3 are all adjustable, and the height of the L4 is fixed.

The injection of the dialysate is realized through the height difference between L1 and L2; the adjustment of the injection flow of the dialysate is realized through the height difference change of the L1 and the L2;

the replenishing liquid medicine/the last liquid medicine is replenished by controlling the height difference between L3 and L1; the injection flow rate of the supplementary liquid medicine/the last liquid medicine is adjusted through the height difference change between the L3 and the L1;

the power for leading the waste liquid in the abdominal cavity of the human body out to the waste liquid collecting device is provided through the height difference between L2 and L4; the adjustment of the waste liquid discharge flow rate is achieved by the change in the height difference between L2 and L4.

It should be noted that the height L1 of the liquid supply bag 1 from the ground, the height L3 of the supplementary medicine bag 7 from the ground, the height L3 of the last medicine bag 8 from the ground, and the height L5 of the consumable box 6 from the ground can be adjusted by the liftable support 9 (as shown in fig. 1), and the height L2 of the human abdominal cavity 2 from the ground can be adjusted by adjusting the lying height of the human body, specifically, the human abdominal cavity can be a bed, a sofa, or the like. In addition, the height of the waste liquid collecting device from the ground is L4, which is generally fixed. If the height L4 of the waste liquid collecting device from the ground needs to be adjusted, the height can be adjusted by a base plate below the waste liquid collecting device.

Liftable support 9 can also set up pulley 90, can realize the bulk movement of system, convenient operation. If liftable support 9 sets up to folded cascade, then can realize that the portable of system carries, made things convenient for the trip greatly. It should be noted that the lifting support can also be arranged in a form of a folding trolley, so that the height adjustment can be realized, the lifting support is convenient to carry, and the normal diagnosis and treatment can be ensured when a patient goes out for a long time.

As a preferred embodiment of the present invention, the present invention includes an APD host 5, and the liquid supply bag 1 is disposed on the APD host 5, as shown in fig. 5, the APD host 5 includes a first heating unit 51, a power supply 52, a consumable box switch control module 53, a PCBA board 54, a display screen 55, a first weighing unit 56, a second weighing unit 57, an upper housing 58, and a lower housing 59, wherein the first weighing unit 56 is disposed on an upper portion of the APD host 5 for weighing a real-time weight of the liquid supply bag. The second weighing unit 57 is disposed at the lower portion of the APD mainframe 5 and is used for weighing the real-time weight of the waste liquid collecting device. The first heating unit 51 is disposed on the top of the APD mainframe 5 and is used for heating the liquid supply bag. The inside of APD host computer 5 is located to consumptive material box 6, consumptive material box on-off control module 53, and consumptive material box on-off control module 53 is connected with consumptive material box 6 for the pipeline of control consumptive material box 6 is opened and is closed. The negative pressure generation unit 4 is provided inside or outside the APD main unit 5. The PCBA board 54 is a control module of the APD host computer 5, and is connected to the consumable box switch control module 53, the first heating unit 51, the first weighing unit 56, the second weighing unit 57, the display screen 55, and the like, and mainly controls the fluid distribution relationship of the system, including controlling the flow rate of the liquid in the liquid supply pipeline and/or the drainage pipeline.

As shown in fig. 5-7, the negative pressure generating unit 4 includes a negative pressure cavity 41 and a negative pressure generator 42 connected to the negative pressure cavity 41, the negative pressure cavity 41 is disposed on the drainage pipeline 20, and the negative pressure cavity 41 is disposed vertically.

After the negative pressure generator 42 is started and the negative pressure cavity 41 reaches the specified pressure, the negative pressure generator 42 stops working;

the liquid in the drainage pipeline 20 continuously flows into the negative pressure cavity 41 under the pressure of the negative pressure cavity 41, and the liquid in the negative pressure cavity 41 continuously flows out under the action of gravity, so that the negative pressure cavity 41 is maintained within a preset pressure range.

With reference to fig. 8 and 9, the negative pressure generator 42 includes a housing 421, an air inlet 422 and an air outlet 423 are provided on the housing 421, and a negative pressure pump 424, a water filter valve 425, a pressure release valve 426 and a pressure sensor 427 are provided in the housing 421. The negative pressure cavity 41 is connected with the air inlet 422 of the negative pressure generator through a negative pressure interface end so as to apply variable negative pressure to the negative pressure cavity.

It should be noted that, this embodiment only shows one embodiment of the negative pressure generator, and the negative pressure generator with other structure may be adopted in the present invention as long as it generates variable negative pressure.

A preferred embodiment of the present invention is to provide a consumable box, in which case the liquid supply pipeline and the drainage tube are provided by the consumable box 6. As shown in fig. 6 and 7, the consumable cartridge 6 includes:

a liquid supply line 10 for connecting to the liquid supply bag;

a drainage line 20 for connection to a waste liquid collection device;

a body end conduit 30 for connection to the abdominal cavity of a human body;

a supplement pipeline 40 for connecting with the supplement medicine bag;

a last tubing 50 for connection to a last fluid bag;

the liquid supply pipeline 10, the drainage pipeline 20, the human body end pipeline 30, the supplement pipeline 40 and the last pipeline 50 are arranged side by side, the end parts of the liquid supply pipeline 10, the drainage pipeline 20, the human body end pipeline 30, the supplement pipeline 40 and the last pipeline 50 are provided with five-way pipes, medical pipe clamps are arranged on the five-way pipes, and the liquid supply pipeline 10, the drainage pipeline 20, the human body end pipeline 30, the supplement pipeline 40 and the last pipeline 50 are connected through the medical pipe clamps 60 to form an intercommunicating pipeline. The medical tube clamp 60 is preferably a robert clamp, but is not so limited. As other embodiments, the medical tube clamp 60 can be a pinch valve, a solenoid valve, a linear motor, etc.

The existing consumable box mostly adopts a labyrinth type consumable box in order to achieve a good dialysis effect. However, the consumable box is simple in structure, only comprises five pipelines, and can be arranged side by side.

The drainage pipeline 20 comprises a drainage branch pipeline 201A, a drainage branch pipeline 201B and a negative pressure interface end 202, the drainage branch pipeline 201A is communicated with one end of the negative pressure cavity 41, and the drainage branch pipeline 201B and the negative pressure interface end 202 are communicated with the other end of the negative pressure cavity 41. The consumable cartridge 6 is connected to the air inlet 422 of the negative pressure generator through the negative pressure interface end 202 on the negative pressure chamber. Thereby applying a variable negative pressure to the negative pressure cavity. The end of the drainage branch pipe 201A is provided with a one-way valve which is connected with a waste liquid collecting device.

With reference to fig. 6 and 7, from right to left, the robert clamps include a first robert clamp 601, a second robert clamp 602, a third robert clamp 603, a fourth robert clamp 604, and a fifth robert clamp 605.

And (3) an injection stage: the third robert clamp 603 and the fourth robert clamp 604 are opened, and the liquid supply line 10 and the human body end line 30 are connected. Under the action of gravitational potential energy of the height difference of L1-L2, the liquid flows into the abdominal cavity of the human body from the liquid supply bag.

And monitoring the weight of the liquid supply bag in real time through the first weighing unit. Reach the prescribed value within a certain range and have no flow rate. The system closes the third and fourth robert clamps 603 and 604 and the implant is completed.

And (3) a supplement stage: the second and third robert clamps 602 and 603 are opened and the replenishment line 40 and the supply line 10 are connected. Under the gravity action of the height difference of L3-L1, the liquid flows into the liquid supply bag from the supplement medicine bag.

And monitoring the weight of the liquid supply bag in real time through the first weighing unit. Comparing the recipe, reaching the set value, the system closes the second robert clamp 602 and the third robert clamp 603, and the injection is completed.

The final supplement stage: the first and third robert clamps 601 and 603 are opened and the last conduit 50 is in communication with the supply conduit 10. Under the gravity action of the height difference of L3-L1, the liquid flows into the liquid supply bag from the last medicine bag.

A drainage stage: the fourth robert clamp 604 and the fifth robert clamp 605 are opened, the negative pressure generator is started, and the pressure in the negative pressure cavity is set to be a preset value P1. Because the end of the drainage branch pipe 201A is provided with the one-way valve, the negative pressure cavity can suck the liquid in the abdominal cavity through the drainage pipeline 20. And when P1 is greater than the corresponding liquid column pressure (L5-L2), peritoneal fluid will be drawn into the negative pressure cavity. When the liquid column pressure of P1 is less than or equal to L6, L6 is L5-L4, the liquid in the negative pressure cavity can be discharged into the waste liquid collecting device.

When the second weighing unit monitors that the weight of the waste liquid barrel changes, the negative pressure pump stops working, and the pressure in the negative pressure cavity is P1 (L5-L2), wherein the liquid column pressure is smaller than P1 and is not larger than L6. Then, the negative pressure in the negative pressure cavity continuously sucks the liquid in the abdominal cavity into the negative pressure cavity through the drainage branch pipe 201B, and the liquid in the negative pressure cavity is influenced by gravity and continuously flows into the waste liquid collecting device through the drainage branch pipe 201A, so that continuous negative pressure is formed on the abdominal cavity.

During the whole drainage process, the system continuously monitors the pressure of the negative pressure cavity, and when the pressure is less than 10% of the set value P1, the negative pressure pump is started again to maintain the pressure of the negative pressure cavity.

In the whole drainage process, the weight change in unit time of the waste liquid collecting device is monitored by the second weighing unit, the real-time flow of the drainage pipeline is obtained, and then whether negative pressure is reapplied to the drainage pipeline or whether the applied negative pressure is adjusted is judged.

In addition, when the second weighing unit judges that the total amount of the liquid in the waste liquid collecting device is more than 80% of the drainage amount of the prescription and the flow rate is not high, the next treatment period is started.

The whole treatment process is repeatedly completed. Before the last drainage in the execution therapy is finished, a pressure release valve of the negative pressure pump is opened to release the pressure of the negative pressure cavity, and the liquid in the whole pipeline naturally flows into the waste liquid collecting device.

The consumable box has simple pipeline and structure, greatly reduces the cost, and makes the APD applied to the family treatment of patients possible. In addition, the simplified consumable box can further reduce the volume of the peritoneal dialysis equipment, and is convenient to carry.

Further, the first heating unit 51 is used for heating the bag, preferably a heating plate. The first heating unit 51 is arranged on the top of the APD mainframe 5, and the liquid supply bag is directly placed on the heating plate. The first weighing unit 56 is disposed below the first heating unit, and is used for weighing the real-time weight of the liquid supply bag, and is preferably a weighing machine.

And a second weighing unit 57 for weighing the real-time weight of the waste liquid collecting device. The second weighing unit 57 is preferably disposed at the lower part of the APD host 5 and in the lower housing 59, and the upper housing 58 and the lower housing 59 are detachably connected. During the use, only need with second weighing unit 57 dismantlement, place below the waste liquid bucket can.

The second weighing unit 57 is connected with the negative pressure generating unit through a control module and is used for acquiring the real-time flow of the drainage pipeline according to the real-time weight of the waste liquid collecting device; and then judging whether to apply negative pressure to the drainage pipeline or adjust the applied negative pressure according to the real-time flow of the drainage pipeline, so as to accurately control the flow of liquid in the drainage pipeline and further ensure that the waste liquid in the abdominal cavity of the human body can be thoroughly emptied.

Specifically, when the real-time flow of the drainage pipeline is smaller than a preset value, the negative pressure generating unit is started; and when the real-time flow of the drainage pipeline is greater than or equal to a preset value, stopping the negative pressure generating unit. When the negative pressure generating unit stops working, the drainage pipeline continuously discharges liquid from the human body by means of suction force generated by the weight of the liquid in the pipeline again, or the liquid is continuously discharged from the human body by means of gravity by adjusting the height relation of L5, L2 and L4. The flow monitoring method has the advantages of simple structure and reliable work, and can provide a quiet dialysis environment for a patient and provide a high-quality dialysis treatment course by matching with the negative pressure generating unit.

As a better embodiment of the present invention, the present embodiment sets a preset value of the dialysate of the waste liquid collecting device, and starts the negative pressure generating unit only when the weight of the dialysate in the waste liquid collecting device does not reach the preset value and the real-time flow of the drainage pipeline is smaller than the preset value; and when the weight of the dialysate in the waste liquid collecting device reaches a preset value or the real-time flow of the drainage pipeline is greater than or equal to the preset value, stopping the negative pressure generating unit. In this scheme, the drainage weight of the waste liquid collecting device is added as the starting and stopping condition of the negative pressure generating unit, when the current weight of the waste liquid collecting device reaches a preset value, the liquid in the abdominal cavity is fully discharged, the negative pressure generating unit is not started at the moment, and the liquid in the abdominal cavity continues to slowly flow out by means of gravity, so that discomfort caused to a patient by intervention of the negative pressure generating unit when the liquid in the abdominal cavity is basically discharged is avoided.

As a more preferable embodiment of the present invention, the present invention further comprises a positive pressure generating unit for providing additional power for guiding the dialysate of the fluid bag into the abdominal cavity of the human body, wherein the positive pressure generating unit can be a fluid bag squeezing device, specifically a pressure plate, an air bag, etc., for squeezing the fluid bag and providing a positive pressure for infusing the dialysate of the fluid bag.

In conclusion, the peritoneal dialysis system of the present invention can implement various therapies for automated peritoneal dialysis, including CCPD, IPD, TPD, etc. The peritoneal dialysis system enables the prescription of dialysis treatment to have greater flexibility, can individually set the injection liquid amount and the waste liquid amount discharged, timely adjusts the dialysis liquid amount suitable for the treatment requirements of patients, enables the patients to automatically exchange peritoneal dialysis liquid during sleeping, and can perform corresponding adjustment of treatment according to the peritoneal capacity and peritoneal functions of the patients, thereby achieving sufficient dialysis and improving the life quality of patients.

As a better embodiment of the utility model, the utility model can also be provided with intelligent control equipment to control the injection flow, the output waste liquid flow, the treatment time and the handover times, and is provided with an early warning correction system to ensure the effectiveness and the safety of treatment to a greater extent.

The utility model will be further explained with reference to the following examples

Aiming at a certain patient, the diagnosis and treatment prescription is 1000ml of initial drainage; total injection amount: 8000ml, single injection 2000 ml; retained abdomen 2000 ml:

the peritoneal dialysis system shown in fig. 1 was used, and set to L1-110 cm, L2-60 cm, L3-170 cm, L4-40 cm, and L5-1000 cm, and the initial negative pressure generated pressure was 10KPa, and the drainage rate was calculated from the change in the weight of the waste liquid collection device. If the initial drainage speed is 100ml/min, the drainage speed is continuously increased along with the continuous negative pressure. Along with the increase of the drainage speed, the initial negative pressure is continuously reduced, so that the drainage speed is maintained at 200ml/min, and the negative pressure is kept at about 4 kpa. The initial drainage is completed.

Liquid injection phase, by difference in height L1-L2: 50cm, the dialysate injection flow is 200ml/min, and the L1 height can be adjusted by the push rod motor, so as to adjust the injection flow.

In the liquid drainage stage, initial negative pressure of 10kpa is loaded, so that waste liquid flows into the waste liquid collecting device from the abdominal cavity. Along with the waste liquid drainage speed is accelerated, the negative pressure is gradually reduced until the waste liquid drainage is stopped. The discharge flow of the abdominal cavity waste liquid is controlled to be 5-250ml/min, the negative pressure is reduced when the flow rate is too high, and the negative pressure can be properly increased when the flow rate is smaller.

When the prescription is changed, the purposes of changing the dialysate injection flow and the discharge flow of the abdominal cavity waste liquid can be achieved by adjusting the height of the APD dialysis machine.

While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the utility model.

Claims

1. A variable pressure-based peritoneal dialysis system, comprising:

at least one negative pressure generating unit;

2. The variable pressure based peritoneal dialysis system of claim 1 further comprising at least one fluid dispensing system connected to the supply line, the drain line to control the flow of fluid in the supply line and/or the drain line.

3. The variable pressure-based peritoneal dialysis system of claim 1, wherein the negative pressure generating unit provides intermittent negative pressure or continuous negative pressure, and the pressure provided by it is variable;

4. The variable pressure-based peritoneal dialysis system of claim 3, wherein the negative pressure generating unit comprises a negative pressure chamber, a negative pressure generator connected to the negative pressure chamber, the negative pressure chamber disposed on a drainage line.

5. The variable pressure-based peritoneal dialysis system of claim 4 wherein the negative pressure generator comprises a housing having an air inlet and an air outlet, a negative pressure pump, a water filter valve, and a pressure relief valve disposed therein;

6. The variable pressure-based peritoneal dialysis system of claim 1, further comprising:

one or more of the L1, L2, L3 is height adjustable.

7. The variable pressure-based peritoneal dialysis system of any of claims 1-6, wherein the supply lines, drain lines, are provided by a consumable cartridge.

8. The variable pressure-based peritoneal dialysis system of claim 7, wherein the consumable cartridge comprises: