CN214571941U

CN214571941U - Lung cancer gene methylation detection kit

Info

Publication number: CN214571941U
Application number: CN202023084587.9U
Authority: CN
Inventors: 刘天津
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-12-19
Filing date: 2020-12-19
Publication date: 2021-11-02
Anticipated expiration: 2030-12-19

Abstract

The utility model discloses a lung cancer gene methylation detect reagent box relates to methylation detection technical field. The lung cancer gene methylation detection kit comprises a mounting plate, wherein the kit is arranged on the outer surface of the front side of the mounting plate. This lung cancer gene methylation detect reagent box, can carry out certain spacing with the reagent bottle of placing in the reagent box, compare in directly placing more firmly, the problem of skew weeping can appear in the reduction, and can carry out spacing pushing down with the reagent bottle, avoided when methylated DNA draws room and detection room not in the same place need transport the kit, the problem of weeping can appear rocking in the reagent bottle of kit inside, avoided the unexpected loss that the too high weeping of extraction cost caused on the one hand, on the other hand has avoided when testing personnel open the kit, be stained with the cross infection that liquid caused, the effectual safety guarantee that strengthens testing personnel, and then the sales volume of product has been improved, this producer has been strengthened, the market competition of enterprise.

Description

Lung cancer gene methylation detection kit

Technical Field

The utility model relates to a methylation detects technical field, specifically is a lung cancer gene methylation detect reagent box.

Background

Lung cancer is the most common primary malignant tumor of the lung, and most of lung cancers originate from bronchial mucosa epithelium, so the lung cancer is also called bronchogenic carcinoma; for over 50 years, the incidence and the fatality rate of lung cancer rapidly rise in all countries in the world, especially in industrially developed countries, the lung cancer is the first place in men who die from cancer, and the incidence part generally has the following rule that the right lung is more than the left lung, the upper lobe is more than the lower lobe, and cancer and swelling can occur from the main bronchus to the bronchiole.

The reagent bottle that current some kits, it is usually with DNA extraction collection directly puts into the inside groove of kit, but has the problem of skew weeping, and partial detection mechanism methylation DNA extraction room is not in same place with the detection room, need transport the kit in the detection room, and difficult the meeting of exempting from during the transportation will collect the box and rock, has consequently improved the risk of weeping once more, to sum up, will directly influence the sales volume of product, and then cause certain negative effects to the market competition of producer, enterprise.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a lung cancer gene methylation detect reagent box to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: a reagent kit for detecting methylation of lung cancer genes comprises a mounting plate, wherein a reagent kit is arranged on the outer surface of the front side of the mounting plate, a T-shaped sliding groove is formed in the front side of the mounting plate, a shaking mechanism is arranged at the bottom of the mounting plate, a rubber block is fixedly arranged in the reagent kit, a placing groove is formed in the rubber block, openings are formed in two sides of the placing groove, an air bag is fixedly adhered in each opening, one side of the air bag extends into the placing groove, a silica gel block is fixedly arranged at the bottom of the inner side of the reagent kit and is positioned in the placing groove, a U-shaped groove is formed in the top of the silica gel block, a rubber pressing plate is arranged in the reagent kit, a storage groove is formed in the bottom of the rubber pressing plate, silica gel pads are fixedly adhered to the inner walls of the placing groove, the U-shaped groove and the storage groove, a closing cover is hinged to the outer surface of the top of the mounting plate, a pressing mechanism is arranged at the bottom of the closing cover, and a sliding block is fixedly arranged on the outer surface of the rear side of the reagent kit, the size of slider and the size phase-match of T shape spout, kit slidable mounting is in the front side of mounting panel.

Preferably, rock the mechanism including bottom plate, diaphragm, sliding block and rock the spring, the bottom surface of mounting panel is provided with the bottom plate, and the top fixed surface of bottom plate installs two sets of diaphragms, and the sliding tray has been seted up to the inside of diaphragm, and slidable mounting has the sliding block in the sliding tray, the both sides of mounting panel and one side fixed connection of two sets of sliding blocks, mounting panel and diaphragm slidable mounting, the top fixed mounting of bottom plate has rock the spring, rocks the bottom of spring and the bottom fixed connection of mounting panel.

Preferably, hold-down mechanism is including fixed box, expanding spring, expansion plate and telescopic link, and the bottom fixed mounting that closes the lid has fixed box, and the inside fixed mounting of fixed box has expanding spring, and expanding spring's one end fixedly connected with expansion plate, the bottom fixed mounting of expansion plate has the telescopic link, and the one end of telescopic link extends to the bottom and the fixedly connected with clamp plate of fixed box, and the clamp plate contacts with rubber clamp plate's top.

Preferably, the fixed surface installs the pull handle in the top of rubber pressing plate, and the outer wall cover of pull handle is equipped with anti-skidding cover, has the condition of slippage when avoiding using.

Preferably, the magnetic sheet is fixedly mounted on the outer surface of the bottom of the closing cover, the mounting groove is formed in the top of the kit, the iron sheet is fixedly mounted in the mounting groove, the magnetic sheet and the iron sheet are attracted through magnetic force, the mounting handle is fixedly mounted on the outer surface of the top of the closing cover, the heat-insulating sleeve is sleeved on the outer wall of the mounting handle, and discomfort caused by the fact that the mounting handle is too cold in use is avoided.

Preferably, the front outer surface fixed mounting of mounting panel has L shape pole, and the one end fixedly connected with drawing board of L shape pole, the top outer surface fixed mounting of mounting panel have the handle of rocking, and the outer wall cover of rocking the handle is equipped with the lag.

Compared with the prior art, the beneficial effects of the utility model are that:

(1) the reagent kit for detecting the methylation of the lung cancer gene can limit the reagent bottles in the reagent kit to a certain extent under the action of the air bag, is more stable than the reagent bottles which are directly placed, and reduces the problem of offset leakage, and the rubber pressing plate can be pressed down when the cover is closed through the matching use of the fixed box, the extension spring, the extension plate, the extension rod and the pressing plate, so that the reagent bottles can be pressed down in a limiting way through the pressing of the rubber pressing plate, the problem that the reagent bottles in the reagent kit shake and leak when the methylation DNA extraction chamber and the detection chamber are not in the same place and the reagent kit needs to be transported is avoided, on one hand, the accidental loss caused by leakage with overhigh extraction cost is avoided, on the other hand, the cross infection caused by liquid adhesion when the reagent kit is opened by detection personnel is avoided, and the safety guarantee of the detection personnel is effectively enhanced, further improving the sales volume of the product and strengthening the market competitiveness of the manufacturer and the enterprise.

(2) This lung cancer gene methylation detect reagent box, through the bottom plate, the diaphragm, the sliding block, the cooperation of rocking spring and rocking handle is used, on the one hand can rock mounting panel and kit from top to bottom when needing, and then can rock even processing with the reagent bottle, need not to take out and rock, the effectual convenience that has improved, on the other hand can conveniently strengthen the buffer when depositing, avoided the foreign matter to fall down and directly cause the destruction to the kit, and this equipment can arrange the DNA liquid that different patients extracted and deposit, with drawing board matched with effect down, can record corresponding patient's information, the problem that testing result and corresponding patient take place the confusion can not appear, effectual authority and the reputation of this detection mechanism of having ensured, and arrange neatly, the parking space of depositing the place has been ensured.

Drawings

Fig. 1 is a schematic structural view of the present invention;

fig. 2 is a schematic perspective view of the mounting plate of the present invention;

FIG. 3 is a schematic structural diagram of the kit of the present invention;

FIG. 4 is a right side view of the kit of the present invention;

fig. 5 is an enlarged view of the part a of the present invention.

In the figure: the device comprises a mounting plate 1, a reagent box 2, a shaking mechanism 3, a bottom plate 301, a transverse plate 302, a sliding block 303, a shaking spring 304, a rubber block 4, an air bag 5, a silica gel block 6, a rubber pressing plate 7, a silica gel pad 8, a pressing mechanism 9, a fixed box 901, a telescopic spring 902, a telescopic plate 903, a telescopic rod 904, a cover 10, a sliding block 11, a 12L-shaped rod, a drawing board 13 and a shaking handle 14.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides a technical solution: a reagent kit for detecting methylation of lung cancer genes comprises a mounting plate 1, a reagent kit 2 is arranged on the outer surface of the front side of the mounting plate 1, a T-shaped sliding groove is formed in the front side of the mounting plate 1, a shaking mechanism 3 is arranged at the bottom of the mounting plate 1, a rubber block 4 is fixedly arranged in the reagent kit 2, a placing groove is formed in the rubber block 4, openings are formed in two sides of the placing groove, an air bag 5 is fixedly adhered in each opening, one side of the air bag 5 extends into the placing groove, DNA reagent bottles which are extracted and collected are placed in the placing groove, then the air bag 5 automatically extrudes the reagent bottles, the reagent bottles placed in the reagent kit 2 can be limited to a certain extent, compared with the reagent bottles which are directly placed, the reagent bottles are more stable, the problem of liquid leakage caused by deviation is solved, a silica gel block 6 is fixedly arranged at the bottom of the inner side of the reagent kit 2, the silica gel block 6 is positioned in the placing groove, a U-shaped groove is formed in the top of the silica gel block 6, the inside of kit 2 is provided with rubber clamp plate 7, the inboard bottom of rubber clamp plate 7 has been seted up and has been put the thing groove, the standing groove, the inner wall of U-shaped groove and putting the thing groove is all pasted and is fixed with silica gel pad 8, the articulated lid 10 that closes of installing panel 1's top surface is installed, the bottom of closing lid 10 is provided with hold-down mechanism 9, the rear side external surface fixed mounting of kit 2 has slider 11, the size of slider 11 and the big or small phase-match of T shape spout, kit 2 slidable mounting is in the front side of installing panel 1.

The shaking mechanism 3 comprises a bottom plate 301, a transverse plate 302, sliding blocks 303 and shaking springs 304, the bottom outer surface of the mounting plate 1 is provided with the bottom plate 301, the top outer surface of the bottom plate 301 is fixedly provided with two groups of transverse plates 302, the inside of the transverse plates 302 is provided with sliding grooves, the sliding blocks 303 are slidably mounted in the sliding grooves, two sides of the mounting plate 1 are fixedly connected with one sides of the two groups of sliding blocks 303, the mounting plate 1 is slidably mounted with the transverse plates 302, the top of the bottom plate 301 is fixedly provided with the shaking springs 304, the bottom of the shaking springs 304 is fixedly connected with the bottom of the mounting plate 1, the pressing mechanism 9 comprises a fixed box 901, a telescopic spring 902, a telescopic plate 903 and a telescopic rod 904, the bottom of the closing cover 10 is fixedly provided with the fixed box 901, the inside of the fixed box 901 is fixedly provided with the telescopic spring 902, one end of the telescopic spring 902 is fixedly connected with the telescopic plate 903, and the bottom of the telescopic rod 904 is fixedly mounted on the telescopic plate 903, one end of the telescopic rod 904 extends to the bottom of the fixed box 901 and is fixedly connected with a pressing plate, the pressing plate is contacted with the top of the rubber pressing plate 7, the outer surface of the top of the rubber pressing plate 7 is fixedly provided with a pull handle, the outer wall of the pull handle is sleeved with an anti-skidding sleeve, the outer surface of the bottom of the closing cover 10 is fixedly provided with a magnetic sheet, the top of the reagent box 2 is provided with a mounting groove, the iron sheet is fixedly mounted in the mounting groove, the magnetic sheet and the iron sheet are attracted by magnetic force, the outer surface of the top of the closing cover 10 is fixedly provided with a mounting handle, the outer wall of the mounting handle is sleeved with a heat insulation sleeve, the rubber pressing plate 7 is placed in the reagent box 2, then the closing cover 10 is closed by the mounting handle, the magnetic sheet and the iron sheet are automatically attracted, the closing cover 10 drives the telescopic rod 904 to press down, the pressing of the telescopic rod 904 is pressed down by the pressing plate, the telescopic spring 902 and the telescopic plate 903 make the telescopic rod 904 and the pressing plate have buffering performance, the problem that reagent bottles in the reagent kit 2 shake and leak when the reagent kit 2 needs to be moved when a methylated DNA extraction chamber and a detection chamber are not in the same place is solved, on one hand, the accidental loss caused by leakage with high extraction cost is avoided, on the other hand, the cross infection caused by liquid adhesion when the reagent kit 2 is opened by a detector is avoided, the safety guarantee of the detector is effectively enhanced, the L-shaped rod 12 is fixedly arranged on the outer surface of the front side of the mounting plate 1, the drawing board 13 is fixedly connected with one end of the L-shaped rod 12, the reagent kit 2 is placed in the T-shaped sliding chute through the sliding block 11, DNA liquid extracted by different patients can be arranged and stored, under the action of matching with the drawing board 13, the information of the corresponding patient can be recorded, the problem that the detection result is disordered with the corresponding patient does not occur, the authority and the reputation of the detection mechanism are effectively guaranteed, and the arrangement is neat, the storage space of the storage place is ensured, the outer surface of the top of the mounting plate 1 is fixedly provided with the shaking handle 14, the outer wall of the shaking handle 14 is sleeved with a protective sleeve, when the reagent bottle needs to be shaken, the shaking handle 14 is held by hands to shake up and down, the transverse plate 302, the sliding block 303 and the shaking spring 304 are used for shaking effectively, on one hand, the mounting plate 1 and the reagent box 2 can be shaken up and down when needed, further, the reagent bottle can be shaken uniformly without being taken out, the convenience of the reagent bottle is effectively improved, on the other hand, the buffer property can be conveniently enhanced when the reagent bottle is stored, and the situation that the reagent box 2 is directly damaged due to the falling of foreign matters is avoided.

The working principle is as follows: place the DNA reagent bottle that will draw the collection in the standing groove, then 5 automatic reagent bottle extrudees with the gasbag, then place rubber pressing plate 7 in kit 2, then will close lid 10 through the installation handle and close, close the automatic attraction mutually of back magnetic sheet and iron sheet, close closing of lid 10 simultaneously and drive telescopic link 904 and push down, the pushing down of telescopic link 904 pushes down rubber pressing plate 7 through the clamp plate, make telescopic link 904 and clamp plate have the resiliency under the effect of expanding spring 902 and expansion plate 903, then place kit 2 in the T shape spout through slider 11, when needs rock it, handheld rocking handle 14 of shaking rocks from top to bottom, diaphragm 302, the slider 303 makes under the effect of rocking spring 304 to rock practically effective.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a lung cancer gene methylation detect reagent box, includes mounting panel (1), its characterized in that: the kit comprises a mounting plate (1), a kit body (2) is arranged on the outer surface of the front side of the mounting plate (1), a T-shaped sliding groove is formed in the front side of the mounting plate (1), a shaking mechanism (3) is arranged at the bottom of the mounting plate (1), a rubber block (4) is fixedly mounted in the kit body (2), a placing groove is formed in the rubber block (4), openings are formed in two sides of the placing groove, an air bag (5) is fixedly pasted in each opening, one side of the air bag (5) extends into the placing groove, a silica gel block (6) is fixedly mounted at the bottom of the inner side of the kit body (2), the silica gel block (6) is located in the placing groove, a U-shaped groove is formed in the top of the silica gel block (6), a rubber pressing plate (7) is arranged in the kit body (2), a storage groove is formed in the bottom of the inner side of the rubber pressing plate (7), silica gel pads (8) are pasted and fixed on the inner walls of the U-shaped groove and the storage groove, the outer surface of the top of the mounting plate (1) is hinged with a closing cover (10), a pressing mechanism (9) is arranged at the bottom of the closing cover (10), a sliding block (11) is fixedly mounted on the outer surface of the rear side of the kit (2), the size of the sliding block (11) is matched with the size of the T-shaped sliding groove, and the kit (2) is slidably mounted on the front side of the mounting plate (1).

2. The kit for detecting the methylation of the lung cancer gene according to claim 1, wherein the kit comprises: rock mechanism (3) including bottom plate (301), diaphragm (302), sliding block (303) and rock spring (304), the bottom surface of mounting panel (1) is provided with bottom plate (301), the top surface fixed mounting of bottom plate (301) has two sets of diaphragms (302), the sliding tray has been seted up to the inside of diaphragm (302), sliding tray slidable mounting has sliding block (303), the both sides of mounting panel (1) and one side fixed connection of two sets of sliding blocks (303), mounting panel (1) and diaphragm (302) slidable mounting, the top fixed mounting of bottom plate (301) has rock spring (304), rock the bottom of spring (304) and the bottom fixed connection of mounting panel (1).

3. The kit for detecting the methylation of the lung cancer gene according to claim 1, wherein the kit comprises: hold-down mechanism (9) including fixed box (901), expanding spring (902), expansion plate (903) and telescopic link (904), close the bottom fixed mounting who covers (10) and have fixed box (901), the inside fixed mounting of fixed box (901) has expanding spring (902), the one end fixedly connected with expansion plate (903) of expanding spring (902), the bottom fixed mounting of expansion plate (903) has telescopic link (904), the one end of telescopic link (904) extends to the bottom and the fixedly connected with clamp plate of fixed box (901), the clamp plate contacts with the top of rubber clamp plate (7).

4. The kit for detecting the methylation of the lung cancer gene according to claim 1, wherein the kit comprises: the outer fixed surface in top of rubber clamp plate (7) installs the pull handle, and the outer wall cover of pull handle is equipped with anti-skidding cover.

5. The kit for detecting the methylation of the lung cancer gene according to claim 1, wherein the kit comprises: the magnetic sheet is fixedly arranged on the outer surface of the bottom of the close cover (10), the mounting groove is formed in the top of the kit (2), the iron sheet is fixedly arranged in the mounting groove, the magnetic sheet and the iron sheet are attracted by magnetic force, the mounting handle is fixedly arranged on the outer surface of the top of the close cover (10), and the heat preservation sleeve is sleeved on the outer wall of the mounting handle.

6. The kit for detecting the methylation of the lung cancer gene according to claim 1, wherein the kit comprises: the outer fixed surface of the front side of mounting panel (1) installs L shape pole (12), the one end fixedly connected with drawing board (13) of L shape pole (12), the top outer fixed surface of mounting panel (1) installs and rocks handle (14), and the outer wall cover that rocks handle (14) is equipped with the lag.