CN214085315U - HLA typing detection kit - Google Patents
HLA typing detection kit Download PDFInfo
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- CN214085315U CN214085315U CN202022676531.6U CN202022676531U CN214085315U CN 214085315 U CN214085315 U CN 214085315U CN 202022676531 U CN202022676531 U CN 202022676531U CN 214085315 U CN214085315 U CN 214085315U
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- hla typing
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- 238000001514 detection method Methods 0.000 title claims description 16
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 28
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 14
- 229910052742 iron Inorganic materials 0.000 claims description 7
- 239000000835 fiber Substances 0.000 claims description 5
- 239000011087 paperboard Substances 0.000 claims description 3
- 239000011111 cardboard Substances 0.000 abstract description 10
- 239000003814 drug Substances 0.000 abstract description 4
- GQWNECFJGBQMBO-UHFFFAOYSA-N Molindone hydrochloride Chemical compound Cl.O=C1C=2C(CC)=C(C)NC=2CCC1CN1CCOCC1 GQWNECFJGBQMBO-UHFFFAOYSA-N 0.000 abstract description 2
- 238000012163 sequencing technique Methods 0.000 description 4
- 241001233242 Lontra Species 0.000 description 2
- 239000002274 desiccant Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 238000000246 agarose gel electrophoresis Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a HLA typing detect reagent box, comprises a box bod, box body back outer wall one side is close to top department integrated into one piece and has the lid, it has the sponge piece to bond on the outer wall of lid bottom, and sponge piece bottom outer wall both sides all set up the recess that is equidistance structure subsection, the inside arrangement of box body has the piece of settling with sponge piece mutual contact, and settle a top outer wall both sides and all set up the arrangement groove that is equidistance structure and distributes, box body front outer wall one side is close to top department and has seted up the draw-in groove, integrated into one piece has the cardboard on the outer wall of lid one side. The utility model discloses when the staff closed the lid, the sponge piece can be detained on settling the reagent bottle on the piece through the recess to protect the inside reagent bottle of kit, avoid the reagent bottle to empty reagent when the transportation simultaneously and flow reagent bottle, and the staff can take out the base plate when storing, then settle the drier in the mounting groove is inside, thereby dry inside the box body, avoid the inside medicament of box body to wet.
Description
Technical Field
The utility model relates to a kit technical field especially relates to HLA typing detect reagent box.
Background
In order to get rid of the laborious reagent formulation and optimization process, more and more experimental steps and detection methods are developed as kits.
At present, current HLA kit is when the transportation, and the inside reagent bottle of kit is emptyd easily, can make reagent flow, and current HLA kit dampproofing ability is relatively poor simultaneously, can influence the save of the inside medicine bottle of kit, consequently, needs to design HLA typing detect reagent box and solves above-mentioned problem urgently.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the problem that the prior HLA kit existing in the prior art can not protect the reagent bottle and the relatively poor moisture-proof capability of the kit when in transportation, and providing the HLA typing detection kit.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
HLA typing detect reagent box, comprises a box bod, box body back outer wall one side is close to top department integrated into one piece and has the lid, it has the sponge piece to bond on the outer wall of lid bottom, and sponge piece bottom outer wall both sides all set up the recess that is equidistance structure subsection, the inside arrangement of box body has the arrangement piece with sponge piece mutual contact, and settles a top outer wall both sides and all set up the arrangement groove that is equidistance structure and distributes, box body front outer wall one side is close to top department and has seted up the draw-in groove, integrated into one piece has the cardboard on the outer wall of lid one side, and bonds on the cardboard bottom outer wall and have the magnetic stripe.
Furthermore, a slot is formed in one side of the outer wall of the bottom of the clamping groove, the clamping plate is inserted into the slot, and an iron sheet in mutual contact with the magnetic strip is bonded to the outer wall of the bottom of the slot.
Furthermore, a screen plate is bonded on the inner wall of the side face of the box body close to the bottom, and the screen plate is in contact with the placing block.
Further, the mounting groove has all been seted up to otter board bottom outer wall both sides, and the inside bonding of mounting groove has the magnetic path.
Further, the base plate is clamped on the inner wall of the side face of the box body close to the bottom, the base plate is in mutual contact with the magnetic block, and a mounting groove is formed in one side of the outer wall of the top of the base plate.
Further, the box body includes the cardboard, all bond on the outer wall of cardboard both sides has the floor, and bonds on the outer wall of floor one side has the fibre layer, it has the thin layer to bond on the outer wall of fibre layer one side.
The utility model has the advantages that:
1. through the sponge piece that sets up, when using this kit, when the staff closed the lid, the sponge piece can be detained on settling the reagent bottle on the piece through the recess to protect the inside reagent bottle of kit, avoid the reagent bottle to empty reagent outflow reagent bottle when the transportation simultaneously.
2. Through the base plate that sets up, when using this kit, the staff can take out the base plate, then settle the drier in mounting groove inside to carry out the drying to box body inside, avoid the inside medicament of box body to wet.
3. Through the floor and the fibrous layer that set up, fibrous layer and floor can be so that the box body has higher resistance to compression and tensile property to improve the life of this box body, article that the box body was inside when avoiding the box body pressurized are impaired.
Drawings
FIG. 1 is a front view of the HLA typing detection kit of the present invention;
FIG. 2 is an expanded view of the main view structure of the cover of the HLA typing detection kit of the present invention;
FIG. 3 is a top view of the front view structure of the case body of the HLA typing detection kit according to the present invention;
FIG. 4 is a top view of the structure of the HLA typing detection kit of the present invention;
fig. 5 is a front view structural cross-sectional view of the HLA typing detection kit according to the present invention;
FIG. 6 is a schematic diagram of the structure of the substrate of the HLA typing detection kit of the present invention;
fig. 7 is a schematic diagram of a box material structure of the HLA typing detection kit according to the present invention.
In the figure: the box comprises a box body 1, a box cover 2, a sponge block 3, a groove 4, a placement block 5, a placement groove 6, a clamping groove 7, a slot 8, a screen plate 9, a mounting groove 10, a magnetic block 11, a base plate 12, a placement groove 13, an iron sheet 14, a magnetic stripe 15, a paper board 16, a rib plate 17, a fiber layer 18, a film layer 19 and a clamping plate 20.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When a component is referred to as being "connected" to another component, it can be directly connected to the other component or intervening components may also be present. When a component is referred to as being "disposed on" another component, it can be directly on the other component or intervening components may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1 to 4, the HLA typing test kit comprises a box body 1, a box cover 2 is integrally formed on one side of the outer wall of the back of the box body 1 near the top, the box cover 2 is used for preventing a reagent bottle in the box body 1 from flowing out of the box body 1, a sponge block 3 is bonded on the outer wall of the bottom of the box cover 2, the sponge block 3 can be contacted and buckled on the reagent bottle with a mounting block 5 so as to protect the reagent bottle, grooves 4 with equal-distance structural sections are respectively formed on two sides of the outer wall of the bottom of the sponge block 3, a mounting block 5 which is contacted with the sponge block 3 is arranged in the box body 1, the mounting block 5 is used for mounting the reagent bottle, mounting grooves 6 with equal-distance structural distribution are respectively formed on two sides of the outer wall of the top of the mounting block 5, the mounting grooves 6 are convenient for mounting the reagent bottle on the mounting block 5, a clamping groove 7 is formed on one side of the outer wall of the front of the box body 1 near the top, a clamping plate 20 is integrally formed on the outer wall of one side of the box cover 2, and the outer wall of the bottom of the clamping plate 20 is bonded with a magnetic strip 15, and the magnetic strip 15 and the iron sheet 14 are in contact, so that the clamping plate 20 is buckled inside the slot 8.
Further, slot 8 has been seted up to 7 bottom outer walls of draw-in groove one side, and slot 8 is used for spacing cardboard 20, and cardboard 20 pegs graft inside slot 8, bonds on the outer wall of 8 bottoms of slot have with magnetic stripe 15 iron sheet 14 of mutual contact, iron sheet 14 be used for making cardboard 20 fix inside slot 8 with the 15 cooperation of magnetic stripe.
Furthermore, a screen plate 9 is bonded on the inner wall of the side surface of the box body 1 close to the bottom, the screen plate 9 is used for supporting the placing block 5, and the screen plate 9 is in mutual contact with the placing block 5.
Further, mounting groove 10 has all been seted up to 9 bottom outer wall both sides of otter board, and mounting groove 10 is used for installing magnetic path 11, and the inside bonding of mounting groove 10 has magnetic path 11, and magnetic path 11 is used for adsorbing and live base plate 12, avoids base plate 12 to break away from box body 1.
Further, the base plate 12 is clamped on the inner wall of the side face of the box body 1 close to the bottom, the base plate 12 is convenient for placing a drying agent in the box body 1, the base plate 12 is in mutual contact with the magnetic block 11, a placing groove 13 is formed in one side of the outer wall of the top of the base plate 12, and the placing groove 13 is used for placing the drying agent.
Further, box body 1 includes cardboard 16, all bonds on the outer wall of 16 both sides of cardboard have floor 17, and floor 17 can improve box body 1's compressive capacity, and bonds on the outer wall of floor 17 one side has fibrous layer 18, and fibrous layer 18 can improve this box body 1's tensile capacity, and it has thin layer 19 to bond on the outer wall of fibrous layer 18 one side, and thin layer 19 can improve this box body 1's waterproof nature.
The working principle is as follows: when the kit is used, a worker takes out the kit, then pulls the box cover 2 to enable the clamping plate 20 to move in the slot 8, so that the magnetic strip 15 is separated from the iron sheet 14, the box cover 2 is conveniently pulled to open the kit, then the worker takes out a reagent bottle to be used from the mounting block 5, then places the extracted tumor tissue DNA in the reagent bottle, then the worker adopts Platinum SuperFiIIDNA polymerase and amplifies the DNA by using a PCR instrument according to the following procedure, then the worker cuts a fragment of about 3.2kb through agarose gel electrophoresis of the amplified product and removes a non-specific amplified fragment, then carries out sequencing by using a sequencing primer, at the moment, the potential deletion mutation polymorphism avoided by the sequencing primer A4Rnew is sequenced, the sequencing primer designed in the exon, and then carries out HLA analysis by using soap typing software and records data, and after the test to DNA, the staff can close lid 2 for sponge piece 3 is detained on the reagent bottle, thereby protects the reagent bottle, and then the staff is placing the suitable position with the kit, and when storing this kit, the staff can be when using this kit, and the staff can take out base plate 12, then settles the drier in mounting groove 13 inside, thereby dry 1 inside of box body, avoid 1 inside medicament of box body to wet with.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (6)
- The HLA typing detect reagent box comprises a box body (1) and is characterized in that a box cover (2) is arranged on one side of the outer wall of the back of the box body (1) close to the top of the box body, a sponge block (3) is bonded on the outer wall of the bottom of the box cover (2), grooves (4) which are distributed in an equidistant structure are formed in two sides of the outer wall of the bottom of the sponge block (3), arranging blocks (5) which are mutually contacted with the sponge block (3) are arranged inside the box body (1), arranging grooves (6) which are distributed in an equidistant structure are formed in two sides of the outer wall of the top of the arranging blocks (5), a clamping groove (7) is formed in one side of the outer wall of the front of the box body (1) close to the top of the box body, a clamping plate (20) is formed on the outer wall of one side of the box cover (2), and a magnetic stripe (15) is bonded on the outer wall of the bottom of the clamping plate (20).
- 2. The HLA typing detection kit according to claim 1, wherein a slot (8) is formed in one side of the outer wall of the bottom of the slot (7), the clamping plate (20) is inserted into the slot (8), and an iron sheet (14) which is in contact with the magnetic strip (15) is bonded to the outer wall of the bottom of the slot (8).
- 3. The HLA typing detection kit according to claim 1, wherein a mesh plate (9) is bonded to the inner wall of the side of the case body (1) near the bottom thereof, and the mesh plate (9) and the mounting block (5) are in contact with each other.
- 4. The HLA typing detection kit according to claim 3, wherein mounting grooves (10) are formed in both sides of the outer wall of the bottom of the screen plate (9), and magnetic blocks (11) are bonded inside the mounting grooves (10).
- 5. The HLA typing detection kit according to claim 1, wherein a base plate (12) is clamped on the inner wall of the side surface of the case body (1) near the bottom, the base plate (12) and the magnetic block (11) are contacted with each other, and a mounting groove (13) is formed on one side of the outer wall of the top of the base plate (12).
- 6. The HLA typing detection kit according to claim 1, wherein the case (1) comprises a paper board (16), ribs (17) are bonded to both outer walls of the paper board (16), a fiber layer (18) is bonded to one outer wall of the ribs (17), and a film layer (19) is bonded to one outer wall of the fiber layer (18).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202022676531.6U CN214085315U (en) | 2020-11-18 | 2020-11-18 | HLA typing detection kit |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202022676531.6U CN214085315U (en) | 2020-11-18 | 2020-11-18 | HLA typing detection kit |
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Publication Number | Publication Date |
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CN214085315U true CN214085315U (en) | 2021-08-31 |
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CN202022676531.6U Active CN214085315U (en) | 2020-11-18 | 2020-11-18 | HLA typing detection kit |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024131029A1 (en) * | 2022-12-21 | 2024-06-27 | 南京亿科人群健康研究院有限公司 | Methylmalonic acidemia-related gene mutation detection kit |
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2020
- 2020-11-18 CN CN202022676531.6U patent/CN214085315U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024131029A1 (en) * | 2022-12-21 | 2024-06-27 | 南京亿科人群健康研究院有限公司 | Methylmalonic acidemia-related gene mutation detection kit |
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