CN211553735U

CN211553735U - Analyzer and detection system

Info

Publication number: CN211553735U
Application number: CN201922037190.5U
Authority: CN
Inventors: 李鸿全
Original assignee: BOE Technology Group Co Ltd
Current assignee: BOE Technology Group Co Ltd
Priority date: 2019-11-22
Filing date: 2019-11-22
Publication date: 2020-09-22
Anticipated expiration: 2029-11-22

Abstract

An analyzer and a detection system. The analyzer includes a first housing, a chip placement structure, and at least one detection unit. The chip placement structure is arranged in the first shell and used for placing a detection chip, and the detection chip is provided with at least one detection area; at least one detection unit is disposed in the first housing, the at least one detection unit being configured to detect one or more detection areas of the detection chip, respectively, when the detection chip is placed on the chip placement structure. The analyzer can detect the contents of various substances in the liquid to be detected in a plurality of detection areas of the detection chip in the detection process.

Description

Analyzer and detection system

Technical Field

The embodiment of the disclosure relates to an analyzer and a detection system.

Background

In recent years, with the improvement of living standard, the requirement of the masses on balanced nutritional diet is higher and higher, and especially for infants taking breast milk as a main nutritional source, the balance of nutrition is particularly important. Detecting the content of trace elements such as calcium, zinc, iron, lactose, protein and the like in the breast milk, and giving a proper nutritional diet instruction to the mother according to the detection result.

SUMMERY OF THE UTILITY MODEL

The embodiment of the disclosure provides an analyzer and a detection system. The analyzer can detect the contents of various substances in the liquid to be detected in the detection chip in the detection process.

At least one embodiment of the present disclosure provides an analyzer comprising: the chip placement device comprises a first shell, a chip placement structure and at least one detection unit. The chip placing structure is arranged in the first shell and used for placing a detection chip, wherein the detection chip is provided with at least one detection area. At least one detection unit is disposed in the first housing, wherein the at least one detection unit is configured to detect one or more detection areas of the detection chip, respectively, when the detection chip is placed on the chip placement structure.

For example, in an analyzer provided by an embodiment of the present disclosure, the at least one detection unit includes at least one photodetecting unit.

For example, in an analyzer provided by an embodiment of the present disclosure, the at least one photodetecting unit each includes at least one light emitting element and at least one photodetecting device.

For example, an analyzer provided in an embodiment of the present disclosure further includes an optical path component disposed in the first housing between the chip placement structure and the detection unit, and configured to transmit light emitted from the at least one light emitting element to the chip placement structure and transmit light reflected from the detection chip placed on the chip placement structure to the at least one photo sensor device.

For example, in an analyzer provided in an embodiment of the present disclosure, the optical path component includes an optical splitter disc, the optical splitter disc includes at least one set of light passing holes respectively corresponding to the at least one photodetecting unit, each set of light passing holes includes at least one light emitting through hole and at least one light reflecting through hole, the at least one light emitting through hole allows light emitted from at least one light emitting element of the corresponding photodetecting unit to pass through, and the at least one light reflecting through hole allows light reflected from a detection chip placed on the chip placement structure to pass through to be transmitted to at least one photoelectric sensing device of the corresponding photodetecting unit.

For example, in an analyzer provided in an embodiment of the present disclosure, a sidewall of the at least one light emitting through hole is an inclined surface, and a sidewall of the at least one light reflecting through hole is an inclined surface.

For example, in an analyzer provided in an embodiment of the present disclosure, each of the at least one photodetecting unit includes two light emitting elements and one photodetecting device, and the two light emitting elements are disposed on opposite sides of the one photodetecting device; the at least one group of light through holes each group comprises two light emitting through holes and one light reflecting through hole, the two light emitting through holes are arranged on two opposite sides of the light reflecting through hole, the two light emitting through holes respectively allow light emitted by the two light emitting elements to pass through, and the light reflecting through hole allows light reflected by a detection chip arranged on the chip arrangement structure to pass through so as to be transmitted to the photoelectric sensing device.

For example, an analyzer provided by an embodiment of the present disclosure further includes a separation member disposed in the first housing between the optical path member and the chip placement structure, wherein the separation member includes a light-transmitting portion configured to pass light emitted from the at least one light-emitting element and light reflected from the detection chip placed on the chip placement structure.

For example, in an analyzer provided in an embodiment of the present disclosure, the light-transmitting portion of the partition member includes at least one transparent window respectively corresponding to the at least one photo-detection unit, so as to respectively allow light emitted from at least one light-emitting element of the corresponding photo-detection unit and light reflected from the detection chip disposed on the chip placement structure to the at least one photo-sensing device of the corresponding photo-detection unit to pass therethrough.

For example, in an analyzer provided by an embodiment of the present disclosure, the partition assembly further includes a substrate including at least one mounting through-hole, and at least one transparent sheet embedded in the at least one mounting through-hole to provide the at least one transparent window.

For example, the analyzer provided by an embodiment of the present disclosure further includes a detection circuit board, the photoelectric detection unit is disposed on the detection circuit board, the detection circuit board includes a first positioning hole, the separation assembly includes a positioning column, and the optical disc includes a second positioning hole, or the separation assembly includes a second positioning hole, and the optical disc includes a positioning column, and the positioning column is inserted into the first positioning hole and the second positioning hole to connect the optical disc, the separation assembly, and the detection circuit board.

For example, in an analyzer provided in an embodiment of the present disclosure, the first housing further includes at least one support portion disposed at a bottom portion of the first housing to provide stable support to the first housing.

For example, an analyzer provided in an embodiment of the present disclosure further includes a rotation driving device, wherein the at least one detection unit includes one detection unit, and the rotation driving device is configured to drive the one detection unit to rotate relative to the chip placement structure.

For example, an analyzer provided in an embodiment of the present disclosure further includes a second housing connected to the first housing, wherein the chip placement structure and the detection unit are disposed in a space enclosed by the first housing and the second housing.

For example, in an analyzer provided in an embodiment of the present disclosure, the second housing is hinged to the first housing at a first side, the second housing is configured to be closable with the first housing at a second side and opened to expose the chip placement structure, and the first side is disposed opposite to the second side.

For example, in an analyzer provided by an embodiment of the present disclosure, the first housing includes a first sub opening and closing member disposed at the second side, and the second housing includes a second sub opening and closing member disposed at the second side, wherein the first sub opening and closing member and the second sub opening and closing member are configured to be coupled to and separated from each other to respectively close and open the first housing and the second housing to each other.

For example, in the analyzer provided in an embodiment of the present disclosure, the second sub opening and closing assembly includes an elongated first lock tongue and an elongated second lock tongue, the first lock tongue and the second lock tongue are arranged side by side in pair, the first sub opening and closing assembly includes a groove and a fastener, the fastener is located in the groove, and a first end of the first lock tongue and a first end of the second lock tongue are configured to be able to extend into the groove and be fastened on the fastener, so that the first housing and the second housing are closed, and to be able to be disengaged from the fastener, so that the first housing and the second housing are opened.

For example, in an analyzer provided in an embodiment of the present disclosure, the second sub opening and closing assembly further includes an elastic member disposed in a middle portion of the first lock tongue and a middle portion of the second lock tongue to elastically connect the first lock tongue and the second lock tongue, and configured to apply an elastic force to tend to place the first lock tongue and the second lock tongue in a state of being snappable on the catch.

For example, in an analyzer provided in an embodiment of the present disclosure, the elastic member is a torsion spring, the torsion spring is configured to apply an elastic force that makes the first end portion of the first latch tongue and the first end portion of the second latch tongue approach to each other, and the second sub opening and closing assembly further includes a switch, the switch is connected to the first latch tongue and the second latch tongue and configured to be operable to separate the first end portion of the first latch tongue and the first end portion of the second latch tongue from the latch member in a state of being latched to the latch member.

For example, an embodiment of the present disclosure provides an analyzer further including a display device disposed on the second housing.

For example, an embodiment of the present disclosure provides that the analyzer further comprises at least one microswitch in signal connection with the display device configured to control content displayed on the display device.

For example, an embodiment of the present disclosure provides the analyzer further including a control device, in signal connection with the detection unit and the display device, configured to receive a detection result of the detection unit and transmit the detection result to the display device, and the display device is configured to display the detection result.

At least one embodiment of the present disclosure also provides a detection system, including: an analyser and a detection chip as claimed in any one of the preceding claims. A detection chip is configured to be placeable on the chip placement structure of the analyzer.

In at least one embodiment of the present disclosure, a detection module of an analyzer includes at least one detection unit, and the analyzer can detect contents of a plurality of substances of a liquid to be detected in a detection chip placed on a chip placement structure of the analyzer during a detection process.

Drawings

To more clearly illustrate the technical solutions of the embodiments of the present disclosure, the drawings of the embodiments will be briefly introduced below, and it is apparent that the drawings in the following description relate only to some embodiments of the present disclosure and are not limiting to the present disclosure.

Fig. 1A is a schematic diagram of an analyzer according to an embodiment of the present disclosure;

fig. 1B is a schematic diagram of an analyzer according to another embodiment of the present disclosure;

fig. 2 is a schematic view of a lower structure of an analyzer according to an embodiment of the present disclosure;

fig. 3 is a partial schematic structural view of a lower portion of an analyzer according to an embodiment of the present disclosure;

fig. 4A is a schematic structural diagram of a detection module and a light path component of an analyzer according to an embodiment of the present disclosure;

fig. 4B is a schematic cross-sectional view of a transparent window of a spacer assembly according to an embodiment of the disclosure;

fig. 5A is a schematic view of a detection principle of an analyzer according to an embodiment of the present disclosure;

FIG. 5B is a graph illustrating a standard curve of absorbance values versus material content for an analyzer according to one embodiment of the present disclosure;

fig. 6A is a schematic structural diagram of an optical disc of an analyzer according to an embodiment of the present disclosure;

FIG. 6B is a schematic cross-sectional view of the light passing hole of the optical splitter along section line E-F in FIG. 6A according to an embodiment of the present disclosure;

fig. 7 is a schematic view of a second housing of an analyzer provided by an embodiment of the present disclosure;

fig. 8 is a schematic structural view of a second housing of an analyzer according to an embodiment of the present disclosure;

fig. 9 is a schematic view of a second sub-opening and closing assembly of the analyzer according to an embodiment of the present disclosure;

fig. 10 is a schematic partial structural view of a second sub opening and closing assembly of the analyzer according to an embodiment of the present disclosure;

fig. 11 is a schematic view of a portion of an analyzer according to another embodiment of the present disclosure;

fig. 12A is a schematic diagram of a detection chip according to an embodiment of the disclosure;

fig. 12B is a schematic structural diagram of a part of a detection chip according to an embodiment of the disclosure;

fig. 12C is an exploded schematic view of a detection chip according to another embodiment of the disclosure; and

fig. 13 is a schematic view of a detection process of an analyzer according to an embodiment of the present disclosure.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present disclosure more apparent, the technical solutions of the embodiments of the present disclosure will be described clearly and completely with reference to the drawings of the embodiments of the present disclosure. It is to be understood that the described embodiments are only a few embodiments of the present disclosure, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the disclosure without any inventive step, are within the scope of protection of the disclosure.

Unless otherwise defined, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this disclosure belongs. The use of "first," "second," and similar terms in this disclosure is not intended to indicate any order, quantity, or importance, but rather is used to distinguish one element from another. Also, the use of the terms "a," "an," or "the" and similar referents do not denote a limitation of quantity, but rather denote the presence of at least one. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents. For convenience of description, in some drawings, "upper", "lower", and the like are given only for indicating a relative positional relationship, and when an absolute position of a described object is changed, the relative positional relationship may also be changed accordingly.

The analytical devices available on the market for detecting the substance content of various liquids, such as breast milk, milk and the like, are mainly large-scale detection devices, which are expensive, complicated to operate and require special training of the operator. The detection device is mainly concentrated in hospitals or detection institutions and provides detection of the substance content for people in need. Therefore, some liquid detection needs to be performed in a hospital or a special detection facility, the process is time-consuming and labor-consuming, and frequent detection is limited for people who need detection. For liquids such as breast milk and milk which need to be frequently detected, it is important to monitor the content of substances regularly. Therefore, the inventor has noted that it is important to provide a portable, compact, simple to operate, home-use analyzer that can detect the substance content of a liquid, such as breast milk.

Lab-on-a-chip (Lab-on-a-chip) refers to a technology that integrates or substantially integrates basic operation units such as sample preparation, biological and chemical reactions, separation and detection, etc. into one chip with several square centimeters, for example, so as to complete different biological or chemical reaction processes and analyze the products. Signals generated in the chip need to be detected, and currently, the most common detection means comprise laser-induced fluorescence, mass spectrometry, ultraviolet, chemiluminescence and the like.

The embodiment of the disclosure provides an analyzer and a detection system. The analyzer includes a first housing, a chip placement structure, and at least one detection unit. The chip placing structure is arranged in the first shell and used for placing a detection chip, and the detection chip is provided with at least one detection area. At least one detection unit is disposed in the first housing, the at least one detection unit being configured to detect one or more detection areas of the detection chip, respectively, when the detection chip is placed on the chip placement structure.

Because the detection module of the analyzer comprises at least one detection unit, the analyzer can respectively detect a plurality of detection areas of the detection chip in the detection process through the at least one detection unit, so that the content of various substances of the liquid to be detected in the detection chip can be detected.

The analyzer and detection system provided by one or more embodiments of the present disclosure will be described in detail below with reference to the accompanying drawings.

For example, in some examples, fig. 1A is a schematic diagram of an analyzer provided by an embodiment of the present disclosure. As shown in fig. 1A, analyzer 1100 includes a first housing 1110, a second housing 1160, and a chip placement structure 1120.

The chip placement structure 1120 is located in the first casing 1110 for placing the detection chip 1200. The first shell 1110 and the second shell 1160 may be opened and closed at one side to facilitate the user to place and retrieve the detection chip 1200, and to prevent the detection of the detection chip from being interfered by external light when the analyzer 1100 is in operation. The analyzer 1100 further includes a detection module located below the chip placement structure 1120 in the first casing 1110 to detect the substance content of the liquid to be detected in the detection chip 1200 placed on the chip placement structure 1120. In use, after preparing the test chip 1200 containing the test sample, a user first opens the first shell 1110 and the second shell 1160, places the test chip 1200 on the chip placement structure 1120, and then closes the first shell 1110 and the second shell 1160. The analyzer 1100 may detect the substance content of the liquid to be detected in the detection chip 1200, and after the detection is completed, the detection result is output, and finally, the user may open the first shell 1110 and the second shell 1160 again to take out the detection chip 1200.

It should be noted that the detection chip 1200 in the present disclosure refers to a chip for integrating or substantially integrating basic operation units such as sample preparation, biological and chemical reactions, separation and detection, and the like into one piece, for example, several square centimeters. For example, the detecting chip 1200 may be a microfluidic chip for detecting the substance content of the liquid to be detected.

For example, in some examples, fig. 1B is a schematic diagram of an analyzer provided by another embodiment of the present disclosure. As shown in fig. 1B, the first casing 1110 includes a first supporting portion 1111 and a second supporting portion 1112, for example, the first supporting portion 1111 and the second supporting portion 1112 are symmetrically disposed with respect to a center line of the first casing 1110. The first supporting portion 1111 and the second supporting portion 1112 are provided at the bottom of the first casing 1110, and each include a supporting surface, for example, to provide stable support for the first casing 1110 on a plane when the analyzer is placed on the supporting surface, preventing the first casing 1110 from being tilted to cause a shift in the relative positional relationship between the internal structures of the analyzer 1100.

Fig. 2 is a schematic view of a lower structure of an analyzer according to the above embodiment of the present disclosure; fig. 3 is a partial structural schematic view of the lower part of the analyzer provided in the above embodiment of the present disclosure; fig. 4A is a schematic structural diagram of a detection module and an optical path component of the analyzer according to the above embodiment of the present disclosure.

As shown in fig. 2, 3, and 4A, the lower portion of the analyzer 1100 includes a first housing 1110 and a chip placement structure 1120. The detection chip 1200 includes a plurality of detection regions, and the detailed structure of the detection chip 1200 can refer to fig. 12A, 12B, and 12C described later. In the example shown in the figure, the chip placement structure 1120 provides a cavity for accommodating and supporting the detection chip 1200 and having a cross-sectional shape substantially the same as that of the detection chip 1200, such as a circular cavity in the figure, and the chip placement structure 1120 may further include a clamping structure for fixing the inserted detection chip, for example, the clamping structure includes a stopper, and the like, which is not limited by the embodiment of the disclosure.

The lower portion of the analyzer 1100 also includes a detection module for detecting the placed detection chip 1200. The detection module may be of various types, including, but not limited to, a photo detection module, for example. The detection module is disposed in the first housing 1110. In the following description, a photodetection module is described as an example. As shown in fig. 4A, the detection module includes at least one detection unit. The detection units may be of various types, including, but not limited to, for example, a photodetector 1131. These photodetecting units 1131 are configured to detect a plurality of detection regions of the detection chip 1200 respectively when the detection chip 1200 is placed on the chip placement structure 1120, and specific examples are described below. For example, an opening may be formed in the circumferential direction of the detection chip 1200, the shape of the opening is the same as the shape of the limit block of the chip placement structure 1120, so that when the detection chip 1200 is placed on the chip placement structure 1120, the opening of the detection chip 1200 is sleeved on the limit block, so that the detection area of the detection chip 1200 and the photoelectric detection unit 1131 are aligned in the direction perpendicular to the photoelectric detection unit 1131, and therefore, a user can more conveniently and accurately place the detection chip 1200 on the chip placement structure 1120. Other alignment modes can be adopted in the embodiments of the present disclosure, and the embodiments of the present disclosure are not limited thereto.

In some embodiments, the outer surface of the first casing 1110 is substantially a half sphere, and the chip placement structure 1120 is located in the first casing 1110 near the upper side of the first casing 1110 to facilitate detecting the insertion of the chip. The chip placement structure 1120 includes a first shielding plate 1301, and the first shielding plate 1301 is connected to the upper side of the first casing 1110, for example, clamped, screwed, etc. The first shielding plate 1301 can shield other stray light outside the first casing 1110 to prevent other light from interfering with the detection result. The receiving chamber of the chip placement structure 1120 has a cylindrical shape, for example, to match the shape of the detection chip 1200. The chip placement structure may also be in other shapes such as a quadrangle and a polygon, which is not limited to this.

For example, in other examples, the first casing 1110 may also have other shapes, such as a rectangular parallelepiped, and the like, which is not limited by the embodiments of the present disclosure.

As shown in fig. 4A, the lower portion of the analyzer 1100 further includes a detection circuit board 1302, the detection circuit board 1302 being disposed below the chip placement structure 1120 in the first housing 1110. The detection module is disposed on the detection circuit board 1302, corresponding to the detection chip 1200 in the axial direction of the first housing 1110. The detection module includes a plurality of photodetection units 1131, and the plurality of photodetection units 1131 respectively correspond to the plurality of detection regions of the detection chip in the axial direction of the first housing 1110. For example, as shown in fig. 4A, a plurality of photoelectric detection units 1131 are uniformly arranged on the same circumference to detect a plurality of detection regions of the detection chip 1200, for example, simultaneously or in a certain order, respectively, so as to detect the contents of a plurality of substances in the liquid to be detected in the detection chip 1200. Due to the structural design that the plurality of photoelectric detection units 1131 are uniformly arranged on the same circumference, crosstalk of light in different photoelectric detection units can be avoided, and the accuracy of optical detection is realized.

For example, in some examples, each photodetecting unit 1131 includes at least one light emitting element and at least one photo-sensing device. As in the example shown in fig. 4A, the photodetection unit 1131 includes two light emitting elements 1132 and one photodetection device 1133. The two photo-luminescent elements 1132 are located on both sides of one photo-sensing device 1133. For example, the distance between two adjacent light emitting elements 1132 in different photodetecting units 1131 is greater than the distance between the light emitting element 1132 and the photo sensor device 1133 in the same photodetecting unit 1131, so as to avoid the interference of optical signals between different photodetecting units 1131. The setting of two light emitting elements 1132 and a photoelectric sensing device 1133 can guarantee that the even incidence of light that light emitting element 1132 emitted is in the detection zone of detecting chip 1200 to can also improve the intensity of the incident light that two light emitting elements 1132 provided and the intensity of the reverberation after detecting chip 1200 reflection, and then improve the stability that the analysis appearance detected.

For example, in some examples, as shown in fig. 4A, the number of photo detection units 1131 is, for example, 6. For another example, the number of the photodetecting units 1131 may also be 2, 3, 4, 5, 7, etc., and the number is determined according to the number of the detection regions of the detection chip 1200, and the number of the photodetecting units 1131 is not limited in the embodiments of the present disclosure.

For example, in other examples, the photodetection unit 1131 may also include a photodetection device 1133 and a light emitting element 1132, and may also implement detection of the liquid to be detected in the detection region of the detection chip 1200. Alternatively, the photodetection unit 1131 may also include a plurality of photodetection devices 1133 and a plurality of light emitting elements 1132, and the plurality of photodetection devices 1133 may detect different substances in the liquid to be detected. The number of the light emitting elements 1132 and the photo sensor devices 1133 is not limited in the embodiments of the present disclosure.

For example, fig. 5A is a schematic view of a detection principle of the analyzer according to the above embodiment of the present disclosure. As shown in fig. 5A, the light emitting element 1132 is used to generate an optical signal, light (incident light) with a specific intensity emitted from the light emitting element 1132 is transmitted to the chip placing structure 1120 to reach the detection chip 1200 placed on the chip placing structure 1120, and then the light reflected by the detection region (detection sample in) of the detection chip 1200 is received by the photo sensor device 1133. The photo-sensor device 1133 receives the optical signal (reflected light) and converts the optical signal into an electrical signal. The intensity of the optical signal received by the photo sensor 1133 can be obtained according to the electrical signal.

For example, in other examples, the light emitting elements 1132 may be provided as one, that is, light emitted by one light emitting element 1132 is irradiated to the detection region of the detection chip 1200 as incident light. The detection principle of the embodiment of the present disclosure is not limited to the number of the light emitting elements 1132.

The absorbance value of the liquid to be detected is calculated according to the following formula:

in the above formula, I₀To detect the incident light intensity of the chip, I is the reflected light intensity of the chip, and A is the absorbance value. The content of the specific substance in the liquid to be detected has a linear relation with the absorbance value. Incident light with a certain wavelength enters a detection area of the detection chip 1200, the liquid to be detected in the detection area reflects light after the light is partially absorbed, and the intensity of the absorbed light and the content of substances in the liquid to be detected in the detection area are in a linear relationship. After the reflected light is received by the photo sensor 1133, an electrical signal is obtained, and the intensity of the reflected light can be obtained according to the magnitude of the electrical signal. The reflected light intensity and the incident light intensity are used as absorbance values obtained by equation (1).

For example, in some examples, the light emitting element 1132 and the photo-sensing device 1133 of the analyzer 1100 need to be calibrated to ensure stability of the light source of the analyzer 1100. The light emitted by light emitting element 1132 of analyzer 1100 is collimated using a standard gray scale plate. The standard gray board is placed on the chip placement structure, the absorbance value of the standard gray board to the incident light of the light emitting element is a known standard absorbance value, the absorbance value obtained after the analyzer 1100 detects the standard gray board is compared with the standard absorbance value, and the light emitted by the light emitting element 1132 of the analyzer 1100 is calibrated according to the comparison result.

For example, a liquid whose kind and content of a substance are known may be used as a calibration test sample, the analyzer 1100 detects coordinate points, such as points D1, D2, D3, D4 and D5, after the absorbance value of the calibration test sample to the absorbance value a and the content C of the substance as shown in fig. 5B, the absorbance value a and the content C of the substance are in a linear relationship, and a standard curve of the absorbance value a and the content C of the substance is obtained after linear fitting from the above five points. It should be noted that the five points in fig. 5B are only an example, multiple points can be obtained by using multiple test samples to obtain a standard curve, and the embodiment of the disclosure is not limited to the specific obtaining process of the standard curve.

For example, in some examples, the absorbance value obtained by detecting the liquid to be detected with the analyzer is substituted into the standard curve of the absorbance value a and the content C of the substance shown in fig. 5B, and the content of the substance corresponding to the absorbance value of the liquid to be detected can be obtained. The contents of the plurality of substances in the liquid to be detected are obtained by detecting the liquid to be detected in the plurality of detection regions of the detection chip 1200, respectively.

For example, in some examples, the Light Emitting element 1132 is a Light Emitting Diode (LED), and the Photo-sensing device 1133 is a Photo-Diode (PD), such as a silicon photodiode. The light emitting diode may emit light of a specific wavelength (e.g., infrared light, red light, green light, etc.), and the light emitting diode of the specific wavelength may be selected according to the kind of the detected substance. The light emitted from the light emitting diodes located in different photodetecting units 1131 have different wavelengths, so that the detection of multiple substances is achieved by the plurality of photodetecting units 1131. For example, the photodetection unit 1131 may select a light emitting element that emits light with a wavelength of 630nm for detecting the content of lactose and fat in the liquid to be detected; the photodetection unit 1131 may also select a light emitting element that emits light with a wavelength of 660nm for detecting the content of calcium and protein in the liquid to be detected.

For example, in some examples, the lower portion of the analyzer 1100 further includes a light path component disposed in the first housing 1110 between the chip placement structure 1120 and the detection module, and configured to transmit light emitted from the at least one light emitting element 1132 to the chip placement structure 1120 and to transmit light reflected from the detection chip 1200 placed on the chip placement structure 1120 to the at least one photo-electric sensing device 1133. The light path component can avoid the interference of light signals among different photoelectric detection units 1131, and ensure the reliability of the detection result.

For example, in some examples, as shown in fig. 4A and 6A, the optical path component includes a beam splitting disk 1141 disposed over the detection module. The beam splitting disk 1141 includes at least one group of light passing holes 1142, and the at least one group of light passing holes 1142 are uniformly arranged on the same circumference of the beam splitting disk 1141 and respectively correspond to the plurality of photodetecting units 1131 in the axial direction of the first housing 1110.

For example, in the present example, as shown in fig. 6A, the number of the groups of the light passing holes 1142 is, for example, 6. For another example, the number of groups of the light transmitting holes 1142 may be 2, 3, 4, 5, 7, etc., corresponding to the number of the photodetecting units 1131. The number of groups of the light-passing holes 1142 is not limited in the embodiments of the disclosure.

For example, in some examples, each set of light passing holes 1142 includes at least one light emitting through hole allowing light emitted from the light emitting element 1132 of the corresponding photodetecting unit 1131 to pass therethrough and at least one light reflecting through hole allowing light reflected from the detection chip 1200 placed on the chip placement structure 1120 to pass therethrough for transmission to the photodetecting device 1133 of the corresponding photodetecting unit 1131. As shown in fig. 6A, each set of light passing holes 1142 includes two light emitting through holes 1143 and one light reflecting through hole 1144. Two light emitting through holes 1143 are located at both sides of the light reflecting through hole 1144, the light emitting through hole 1143 corresponds to the light emitting element 1132 in the photodetecting unit 1131, and the light reflecting through hole 1144 corresponds to the photodetecting device 1133 in the photodetecting unit 1131. The light emitted from the light emitting element 1132 is incident on the chip placement structure 1120 after passing through the light emitting through hole 1143, and the light reflected from the sensing chip 1200 placed on the chip placement structure 1120 is received by the photo sensor device 1133 after passing through the light reflecting through hole 1144. The optical disc 1141 can avoid the interference of optical signals between different photoelectric detection units 1131, and ensure the reliability of the detection result.

For example, in some examples, as shown in fig. 6B, the side wall of the light emitting through hole 1143 of the light passing hole 1142 is a slope, and the opening of the side of the light emitting through hole 1143 away from the photodetection unit 1131 is larger than the opening of the side of the light emitting through hole 1143 close to the photodetection unit 1131, thereby increasing the irradiation area of the light emitted from the light emitting element 1132 on the detection chip 1200. The side wall of the light emission through hole 1143 forms an angle α with the X direction (perpendicular to the axial direction of the spectroscopic disk 1141). The included angle α can range, for example, from about 130 degrees to about 140 degrees, and can also range, for example, from about 135 degrees. The side wall of the light emitting through hole 1144 of the light passing hole 1142 is an inclined surface, and the opening of the side of the light reflecting through hole 1144 far away from the photodetecting unit 1131 is larger than the opening of the side of the light reflecting through hole 1144 close to the photodetecting unit 1131, so that the interference between the light emitted from the light emitting element 1132 and the light reflected from the detection chip 1200 placed on the chip placing structure 1120 can be avoided. The side wall of the light emission through hole 1144 forms an angle β with the X direction (perpendicular to the axial direction of the spectroscopic disk 1141). The included angle β may range from about 115 degrees to about 125 degrees, for example, and the included angle β may range from about 120 degrees. It should be noted that the word "about" indicates that the value may vary within, for example, ± 15%.

For example, in some examples, the light emission through hole 1143 is, for example, a rectangular hole as shown in fig. 6A, and the opening of the light emission through hole 1143 on the side close to the photodetection unit 1131 has a size range in the circumferential direction and the radial direction, for example, about 0.8mm to 1 mm. Also for example, the size of the light emission through hole 1143 in the circumferential direction and the radial direction is, for example, about 0.8 mm. The light reflecting through holes 1144 are, for example, circular holes as shown in fig. 6A, and the diameter of the light reflecting through holes 1144 ranges from about 0.8mm to about 1 mm. For another example, the size of the opening of the light reflection through hole 1144 on the side close to the photodetection unit 1131 in the circumferential direction is, for example, about 0.8 mm. It should be noted that the word "about" indicates that the value may vary within, for example, ± 15%. For example, the size of the light transmitting through hole 1143 and the diameter of the light reflecting through hole 1144 may be selected to be slightly larger than 1mm according to the requirement of processing, and no optical crosstalk may occur between two adjacent light transmitting holes 1142. The specific dimensions of the light emitting through hole 1143 and the light reflecting through hole 1144 are not limited in the embodiments of the disclosure.

For example, in other examples, the shape of the light emitting through hole 1143 may also be a triangle, a circle, a polygon, etc., and the shape of the light reflecting through hole 1144 may also be a rectangle, a triangle, a polygon, etc., and the embodiments of the disclosure are not limited to the shapes of the light emitting through hole 1143 and the light reflecting through hole 1144.

For example, in some examples, the spectroscopy disk 1141 further includes at least one second positioning aperture. As shown in fig. 6A, the light splitting disc 1141 includes three second positioning holes 1145 uniformly distributed on the same circumference. The number of the second positioning holes 1145 may also be 2, 4, etc., which is not limited in the embodiments of the disclosure. As shown in fig. 4A, the first positioning hole 1303 of the detection circuit board 1302 is provided at a position of the detection circuit board 1302 opposite to the second positioning hole 1145 of the spectroscopic disk 1141. The first positioning hole 1303 and the second positioning hole 1145 of the detection circuit board 1302 are used for mounting and positioning the light splitting disc 1141 and the detection circuit board 1302, so that the photoelectric detection unit 1131 corresponds to the light through hole 1142.

For example, in some examples, as shown in fig. 3 and 6A, the light splitting disc 1141 further includes a stop block 1146 disposed at an edge of the light splitting disc 1141. The limiting block 1146 extends into the chip placing structure 1120, so as to match with the shape of the detection chip 1200, when the detection chip 1200 is placed in the chip placing structure 1120, the position of the detection chip 1200 is fixed, and thus a plurality of detection regions of the detection chip 1200 are respectively corresponding to the light through hole 1142 of the light splitting disc 1141 and the photoelectric detection unit 1131.

For example, in other examples, the stop block 1146 may also be disposed on other structures of the analyzer 1100, such as the first shield 1301. For another example, the limiting block 1146 may be replaced by another structure that can realize alignment and matching with the detection chip 1200, which is not limited in the embodiments of the present disclosure.

For example, in some examples, as shown in fig. 4A, the lower portion of analyzer 1100 further includes a separation assembly 1150, such as a separation plate, located in first housing 1110 and disposed between the optical path assembly and chip placement structure 1120. That is, the separation member 1150 is located above the optical path member and below the chip placement structure 1120. The partition assembly 1150 includes a light-transmitting portion 1151 configured to allow light emitted from the light emitting element 1132 of the photodetection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to pass therethrough. The detection chip 1120 is located on a partition component 1150, and the partition component 1150 is used for preventing the penetration of the liquid to be detected in the detection area of the detection chip 1120, for example, and can also provide a protection function for the optical path component and the like below. In other examples, a lower disposed divider assembly 1150 of analyzer 1100 may be removable for replacement.

For example, in some examples, as shown in fig. 4A, the light-transmissive portion 1151 of the separating assembly 1150 includes at least one transparent window 1152 respectively corresponding to the plurality of photo-detection units 1131 to respectively allow light emitted from at least one light-emitting element 1132 of the corresponding photo-detection unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to pass through to at least one photo-sensing device 1133 of the corresponding photo-detection unit 1131.

For example, in the present example, as shown in fig. 4A, the number of sets of transparent windows 1152 is, for example, 6. For another example, the number of groups of transparent windows 1152 may be 2, 3, 4, 5, 7, etc., corresponding to the number of light-transmitting holes 1142. The disclosed embodiments are not limited by the number of sets of transparent windows 1152.

For example, in some examples, as shown in fig. 4A and 4B, each transparent window 1152 includes a first through-hole 1153, a first groove 1154, and a transparent sheet 1155. First via 1153 has a diameter smaller than that of first groove 1154, and first groove 1154 is located on a side of partition member 1150 adjacent to chip placement structure 1120 for placing transparent sheet 1155. A transparent sheet 1155 is placed in the first groove 1154 to allow light emitted from the two light emitting elements 1132 of the corresponding photodetecting unit 1131 and light reflected from the detection chip 1200 placed on the chip placement structure 1120 to the photodetecting device 1133 of the corresponding photodetecting unit 1131 to pass through.

For example, in some examples, transparent sheet 1155 may be a glass sheet or the like.

For example, in other examples, the light-transmissive portion 1151 may be other light-transmissive structures, such as a light-transmissive hole and a structure formed by the transparent sheet 1155, or a structure formed by removing the transparent sheet 1155 in the transparent window 1152. The embodiment of the present disclosure is not limited to a specific structure of the light-transmitting portion 1151.

For example, in other examples, the separating member 1150 may also be an integral transparent structure without providing the transparent window 1152, for example, the separating member 1150 is made of a transparent material, thereby allowing light emitted from the light emitting element 1132 of the photodetecting unit 1131 and light reflected from the detecting chip 1200 placed on the chip placing structure 1120 to the corresponding photodetecting device 1133 of the photodetecting unit 1131 to pass through and preventing the liquid to be detected in the detecting chip 1200 from leaking. The disclosed embodiments are not limited thereto.

In other examples, the separating assembly 1150 may not be included, and a transparent window is disposed on the light-passing hole of the spectroscopic disk 1141, so that the spectroscopic disk 1141 can also prevent the liquid to be detected from penetrating into the detection area of the detection chip 1120.

For example, in some examples, as shown in fig. 4A, partition assembly 1150 further includes a plurality of positioning posts 1156 disposed on a side of partition assembly 1150 proximate to optical splitting tray 1141. For another example, the separating assembly 1150 includes three positioning posts 1156, and the three positioning posts 1156 correspond to the positioning holes 1145 of the light splitting tray 1141 and the positioning holes 1303 of the detecting circuit board 1302. Positioning posts 1156 of the partition assembly 1150 are mounted in positioning holes 1145 of the light splitting disc 1141 and positioning holes 1303 of the detection circuit board 1302, so that the partition assembly 1150, the light splitting disc 1141 and the detection circuit board 1302 are fixed, and the light transmitting portion 1151 of the partition assembly 1150, the light transmitting hole 1142 of the light splitting disc 1141 and the photoelectric detection unit 1131 are aligned in the axial direction of the first housing 1110.

For example, in other examples, the second positioning hole 1145 is disposed on the separating component 1150, the positioning pillar 1156 is disposed on the spectroscopic disk 1141, the positioning pillar 1156 extends to the upper and lower sides of the spectroscopic disk 1141, and the positioning pillar 1156 can also be installed in the positioning hole 1145 of the spectroscopic disk 1141 and the positioning hole 1303 of the detection circuit board 1302, so as to fix the separating component 1150, the spectroscopic disk 1141 and the detection circuit board 1302. The installation manner of the separation assembly 1150, the light splitting tray 1141 and the detection circuit board 1302 is not limited in the embodiments of the present disclosure.

For example, in other examples, separation assembly 1150, spectroscopy tray 1141, and detection circuit board 1302 may be secured in other ways, such as with double-sided tape, with snaps, and so forth.

For example, in some examples, as shown in fig. 7, the analyzer 1100 further includes a second housing 1160, the second housing 1160 being coupled to the first housing 1110. The chip placement structure 1120 and the detection module are disposed in the space enclosed by the first shell 1110 and the second shell 1160. For example, in the present embodiment, the detection module as shown in fig. 2 and 3 is disposed on the detection circuit board 1302 and located in the first housing 1110. The first shell 1110 and the second shell 1160 are connected at the first side 1161, and the first shell 1110 and the second shell 1160 are relatively closed and opened at the second side 1162, so as to place the detection chip 1200 on the chip placement structure 1120 or take out the detection chip 1200 from the chip placement structure 1120. It should be noted that, in the example in the drawings, the first side 1161 is a side of the first casing 1110 and the second casing 1160 which are connected to each other, the second side 1162 is a side of the first casing 1110 and the second casing 1160 which are opened and closed relatively, that is, a side on which the detection chip 1200 is placed, the first side 1161 is disposed opposite to the second side 1162, and a relative position of the first side 1161 and the second side 1162 does not constitute a limitation on the embodiment of the present disclosure. The first shell 1110 is substantially hemispherical, and the shape of the opening below the first shell 1110 is the same as the shape of the opening above the second shell 1160, so that a closed space into which external ambient light cannot enter can be formed when the first shell 1110 and the second shell 1160 are closed, thereby facilitating the detection of the analyzer 1100.

For example, in another example, the shape of the second casing 1160 may be, for example, a rectangular parallelepiped, and the opening shape of the second casing 1160 may be matched with the opening shape of the first casing 1110 to form a sealed space, which is not limited in the embodiment of the present disclosure.

For example, in some examples, as shown in fig. 2 and 7, the second shell 1160 is hingedly connected to the first shell 1110 at a first side 1161. The second shell 1160 is configured to be closed with the first shell 1110 at the second side 1162 and opened to expose the chip placement structure 1120. The first side 1161 is disposed opposite the second side 1162.

For example, in some examples, as shown in fig. 2, the first shell 1110 is hinged to the second shell 1110 at a first side 1161 via a hinge shaft 1163. A spring (e.g., a torsion spring) may be further provided at the hinge shaft 1163 so that the second housing 1160 is tilted up by an elastic force of the spring after the first and

second housings

1110 and 1160 are opened at the second side.

For example, in some examples, as shown in fig. 8, the second housing 1160 further includes a second shield 1304 coupled to an underside of the second housing 1160, e.g., snapped, screwed, etc. The second shielding plate 1304 and the first shielding plate 1301 in the first casing 1110 together form an accommodating space for the detection chip. The second shielding plate 1304 can shield other stray light in the second housing 1160 to prevent interference of other light rays on the detection result.

For example, in some examples, as shown in fig. 3 and 8, the first shell 1110 includes a first sub-shutter assembly 1181 disposed on the second side 1162, and the second shell 1160 includes a second sub-shutter assembly 1182 disposed on the second side 1162. The first and second sub open/

close assemblies

1181 and 1182 are configured to be coupled to and separated from each other, so that the first and

second housings

1110 and 1160 are closed and opened with respect to each other, respectively. When the first shell 1110 and the second shell 1160 are opened, the detection chip 1200 is placed on the chip placing structure 1120, and then the first shell 1110 and the second shell 1160 are closed, and the detection of the substance is started.

As shown in fig. 3, 8 and 9, the second sub opening and closing assembly 1182 includes an elongated first lock tongue 1183 and an elongated second lock tongue 1184, and the first lock tongue 1183 and the second lock tongue 1184 are paired and arranged substantially side by side in the second housing 1160. The first latch 1183 and the second latch 1184 may be fixed to the second shielding plate 1304. The fixing means is, for example, a screw connection or the like. The first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 are exposed out of the second shielding plate 1304. The first sub opening and closing component 1181 includes a groove 1187 and a latch 1188, and the latch 1188 is located in the groove 1187. First end 1185 of first latch tongue 1183 and first end 1186 of second latch tongue 1184 are configured to extend into recess 1187 and snap onto snap member 1188 to close first shell 1110 and second shell 1160 and to disengage from the snap member to open first shell 1110 and second shell 1160.

For example, in some examples, as shown in fig. 8, the analyzer 1100 further includes a fixing member 1309, and a middle portion of the first latch 1183 and a middle portion of the second latch 1184 are fixed to the second shielding plate 1304 by the fixing member 1309.

For example, in some examples, the second sub opening and closing assembly 1182 further includes an elastic member disposed in the middle of the first latch tongue 1183 and the middle of the second latch tongue 1184 to elastically connect the first latch tongue 1183 and the second latch tongue 1184, and configured to apply an elastic force to tend to place the first latch tongue 1183 and the second latch tongue 1184 in a state of being snapped onto the snap member 1188.

For example, in some examples, as shown in fig. 9, the elastic member is a torsion spring 1190 to apply an elastic force to make the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 approach each other, so that the first end 1185 of the first latch 1183 and the first end 1186 of the second latch 1184 are in a clamped state. A second end 1194 of the first latch tongue 1183 and a second end 1195 of the second latch tongue 1184 extend outside of the second housing 1160.

For example, in some examples, by reducing the opening distance between

second ends

1194 and 1195 of first and

second lock tongues

1183 and 1184, first ends 1185 and 1186 of first and

second lock tongues

1183 and 1184 are separated from clasp 1188 in a state of being clasped on clasp 1188, thereby opening first and

second housings

1110 and 1160.

For example, in some examples, the second sub opening and closing assembly 1182 further includes a switch disposed in a middle portion of the first latch tongue 1183 and a middle portion of the second latch tongue 1184, and connected to the first latch tongue 1183 and the second latch tongue 1184. And the switch is configured to be operable such that the first end 1185 of the first latch bar 1183 and the first end 1186 of the second latch bar 1184 are disengaged from the catch 1188 in a state of being caught on the catch 1188.

For example, in some examples, as shown in fig. 9, the second sub opening and closing assembly 1182 further includes a micro switch 1305a and a micro switch 1305b, the micro switch 1305a is disposed at the second end 1194 of the first latch tongue 1183, and the switch 1305b is disposed at the second end 1195 of the second latch tongue 1184. One of the micro-switch light 1305a and the micro-switch 1305b is used to realize a switching function of the analyzer 1100, and the other is used to realize a function of controlling display of a detection result of the analyzer 1100. For example, long pressing the microswitch 1305a turns on the analyzer 1100 to start detection of the detection chip 1200, and short pressing the microswitch 1305a turns off the analyzer 1100; pressing the microswitch 1305b selects the detection result to be displayed.

For example, in some examples, as shown in fig. 9, the second sub opening and closing assembly 1182 further includes a rotating shaft 1189 connecting a middle portion of the first locking tongue 1183 and a middle portion of the second locking tongue 1184, and the torsion spring 1190 is sleeved on the rotating shaft 1189.

For example, in some examples, as shown in fig. 10, a connector 1192 is disposed in the middle of the first latch tongue 1183 of the second sub-opening and closing assembly 1182, and the surface of the connector 1192 opposite to the second latch tongue 1184 is a slope, forming a limit track 1191. The limiting track 1191 is used to limit an opening and closing angle of the first lock tongue 1183 and the second lock tongue 1184, so as to prevent that an opening distance between the first end 1185 of the first lock tongue 1183 and the first end 1186 of the second lock tongue 1184 is too small and an opening distance between the second end 1194 of the first lock tongue 1183 and the second end 1195 of the second lock tongue 1184 is too large, which may cause an opening angle of the second casing 1160 with respect to the first casing 1110 to be too large, for example, an angle between the second casing 1160 and the first casing 1110 is greater than 90 degrees, so that the second casing 1160 rolls over in a direction away from the second side 1162, and the analyzer 1100 is at risk of falling.

For example, in some examples, as shown in fig. 7, analyzer 1100 further includes a display device 1170 disposed on second housing 1160. The display device 1170 may be, for example, a liquid crystal display device, an Organic Light Emitting Diode (OLED) display device, electronic paper, a digital tube, or the like, and displays the detection result of the analyzer 1100.

For example, in some examples, as shown in fig. 7, 8, and 9, the analyzer 1100 further includes a silicone sleeve 1306 disposed over the second end 1194 of the first latch 1183 and the second end 1195 of the second latch 1184 for aesthetic, dust-proof, and light-proof effects in the second housing 1160.

For example, in some examples, as shown in fig. 9, light shields 1193 are disposed on a first end 1185 of the first latch tongue 1183 and a first end 1186 of the second latch tongue 1184, respectively, to shield light in the second housing 1160.

For example, in some examples, as shown in fig. 5A, the analyzer 1100 further includes a control device 1310 in signal connection with the photodetection unit 1131 and the display device 1170. The control device 1310 is configured to receive the detection result of the photodetection unit 1131 and transmit the detection result to the display device 1170, and the display device 1170 may display the received detection result. For example, the control device may be a processor, which may be a Central Processing Unit (CPU), a data processor (DSP), etc., and a memory, which may be a semiconductor memory, etc., for storing computer code for execution on the processor, storing data, etc. The control device 1310 also realizes a switching function of the analyzer 1100 and a function of controlling the display of the detection result on the display device 1170 together with the micro-switch 1305a and the micro-switch 1305 b. For example, pressing the microswitch 1305a for a long time turns on the analyzer 1100 to start the detection of the detection chip 1200, and pressing the microswitch 1305a for a short time turns off the analyzer; by controlling the display contents of the display device 1170 by pressing the microswitch 1305b, the detection result can be viewed on the display device 1170 according to the selection.

For example, in some examples, as shown in fig. 5A, analyzer 1100 further includes a sound generator 1311, a signal transmitter-receiver 1312, and the like. The sound emitting device 1311 is, for example, a speaker, and emits a sound for reminding as needed; the signal transmitting and receiving device 1312 includes, for example, an antenna, a modem, and the like, and is configured to perform communication, for example, communication using bluetooth, WIFI, mobile communication (e.g., 2G/3G/4G/5G, and the like), and thereby may send the detection result to other devices (e.g., a mobile terminal such as a mobile phone and a tablet computer, or a server, for example), for example, uploading the detection result to an Application (APP) installed on the mobile terminal such as a mobile phone in real time; or receive control signals from other devices to control the operation of the analyzer by the control device, for example, may cooperate with the analyzer 1100 through an Application (APP) installed on a mobile terminal, such as a cell phone. For example, in some examples, analyzer 1100 also includes a temperature sensor for monitoring the ambient temperature of analyzer 1100. Since some liquids to be detected have certain requirements on the temperature at the time of detection, for example, a temperature in the range of about 25 ℃ to 35 ℃ is required. Therefore, detecting the ambient temperature of the analyzer 1100 can ensure the accuracy of the detection result.

For example, in some examples, analyzer 1100 can also include a humidity sensor for detecting the ambient humidity of analyzer 1100. In the detection process, some liquid to be detected has certain requirements on the humidity during detection, for example, the liquid to be detected and test paper in a chip detection area generate a color reaction, and if the humidity is too low, the test paper may fade to influence the detection result. The control of the environmental humidity in the detection process is beneficial to ensuring the accuracy of the detection result.

For example, in some examples, as shown in fig. 3, analyzer 1100 further includes a battery 1307 disposed in first housing 1110. The battery 1307 supplies power to each device in the analyzer 1100 that needs to use electric power, for example, a control device, a display device, a detection module, and the like. For example, the battery 1307 may be a primary battery or a secondary battery, which may include a nickel-metal hydride battery, a nickel-cadmium battery, a lead-acid battery, a lithium ion battery, or the like. The analyzer 1100 provided by the embodiment of the present disclosure has a simple structure and consumes less power, thereby having a longer standby time for the convenience of users. As another example, analyzer 1100 can also use power cords to provide power to various devices that require power. Battery or direct power may be selected depending on the requirements of the analyzer 1100 in use.

For example, in some examples, as shown in fig. 3, analyzer 1100 further includes a weight 1308 disposed in first housing 1110 and below battery 1307. The balancing weight 1308 is used for moving the gravity center of the analyzer 1100 downwards, so that the analyzer 1100 is more stable when placed on a horizontal plane for use, and the detection chip 1200 can be difficult to move when placed on the chip placement structure 1120, and the reliability of the detection result is ensured.

In addition, in at least one embodiment, the analyzer has the characteristics of small volume, simple structure and easiness in operation, is suitable for being used at home, and can monitor the content of various substances in liquid such as breast milk at any time.

Another embodiment of the present disclosure also provides an analyzer, as shown in fig. 11, which includes a first housing 2110, a chip placing structure 2120, and a detection module. A chip placing structure 2120 is provided in the first housing 2110 for placing the detection chip 1200; the detection chip 1200 has at least one detection zone. A detection module, e.g. a photo detection module, comprising e.g. at least one photo detection unit 2132, e.g. a single photo detection unit, is rotatably arranged in the first housing relative to the chip placement structure 2120. The photo detection unit 2132 is configured to detect the detection regions of the detection chip 1200 by relative rotation with the detection chip 1200 when the detection chip 1200 is placed on the chip placement structure 2120, for example, the detection chip 1200 may be rotated or the photo detection unit may be rotated to detect the detection regions of the detection chip 1200 respectively. For example, the photodetection unit 2132 includes at least one light emitting element and at least one photo sensing device, and further includes, for example, only a photo sensing device.

In one example, the photoelectric detection unit 2132 of the analyzer is rotatably disposed in the first housing 2110 relative to the chip placement structure 2120, and the analyzer can detect a plurality of detection regions of the detection chip respectively through one photoelectric detection unit of the detection module, so as to detect the contents of a plurality of substances in the liquid to be detected in the detection chip. In this example, the same light emitting element included in the photodetecting unit 2132 can emit light with different wavelengths as needed for corresponding detection of different detection samples.

The present embodiment differs from the analyzer provided in the previous embodiments in that the detection module in the present embodiment is relatively rotatable in the first housing with respect to the chip placement structure, and the detection module includes only at least one photodetecting unit. The following describes the structural differences between the present embodiment and the foregoing embodiments.

For example, in some examples, as shown in fig. 11, the detection module is disposed on a detection circuit board 2302. A center axis 2400 is provided at the center of the inspection circuit board 2302. The analyser also comprises a rotary drive 2500 connected to the control means and thereby controlled by the control means. The rotation driving device 2500 may be, for example, a servo motor, a stepping motor, or the like. The other end of the central shaft 2400 is connected to the rotation driving device 2500, and the rotation driving device 2500 drives the central shaft 2400 to rotate, so as to drive the photoelectric detection unit 2132 of the detection module to rotate relative to the chip placement structure 2120.

For example, in some examples, the at least one photodetecting unit comprises one photodetecting unit, and the rotation driving device is configured to drive the one photodetecting unit to rotate with respect to the chip placement structure.

For example, in some examples, compared to the foregoing embodiments, the analyzer of this embodiment may connect the optical splitter disc and the partition component of the optical path component with the first housing, and may not be connected with the detection circuit board, so as to ensure that the light-passing hole of the optical splitter disc and the light-passing portion of the partition component correspond to the detection area of the detection chip.

For another example, in some examples, compared to the foregoing embodiments, the analyzer of the present embodiment may change the light passing hole of the optical splitter disk of the optical path component and the light passing portion of the partition component into one set, and correspond to the detection module. The light splitting disc and the separating assembly rotate together with the detecting circuit board 2132, so that the detecting chip 1200 is placed on the chip placing structure 2120, and the position of the detecting chip 1200 is not moved. For example, a position-limiting elastic sheet may be disposed on a side wall of the chip placing structure, and when the detecting chip 1200 is placed on the chip placing structure 2120, the position of the detecting chip is fixed.

For example, in some examples, the rotation driving device 2500 receives a signal from the control device, and controls the rotation angle of the photodetecting unit 2132, so that the rotation is stopped when the photodetecting unit 2132 rotates to a position corresponding to a detection region of the detection chip 1200, and the photodetecting unit 2132 detects the substance content in the detection region; the control device receives the electrical signal from the photoelectric sensing device of the photoelectric detection unit 2132, rotates the photoelectric detection unit 2132 to a position corresponding to another detection region of the detection chip 1200 again, and then starts to detect the substance content in the detection region. In this way, the analyzer can sequentially perform substance content detection on the detection regions of the detection chip 1200, thereby obtaining the contents of various substances in the liquid to be detected.

At least one embodiment of the present disclosure provides a detection system, which includes the analyzer and the detection chip described in any of the above embodiments, for example, provided as a kit. The detection chip is configured to be placeable on a chip placement structure of the analyzer.

Fig. 12A is a schematic diagram of a detection chip according to an embodiment of the disclosure, where the detection chip may be applied to the detector according to the above embodiment; fig. 12B is a schematic structural diagram of a part of the detection chip according to the above embodiment of the disclosure; fig. 12C is an exploded schematic view of a detection chip according to another embodiment of the disclosure.

As shown in fig. 12A and 12B, the detection chip includes a cover plate 1201 and a substrate 1203. The cover plate 1201 has a sample inlet 1202 and is closely attached to the base plate 1203. The substrate 1203 is made of a transparent material to allow light emitted from the photodetection unit 1131 in the analyzer 1100 to enter the detection chip 1200 and light reflected by the detection chip 1200 to be transmitted to the photodetection unit 1131.

For example, in some examples, as shown in fig. 12B, a plurality of micro flow channels 1205, a plurality of detection regions 1206, and one calibration region 1207 are provided on the surface of the cover plate 1201 opposite to the substrate 1203. The detection chip includes 5 detection zones 1206. Each detection region 1206 is communicated with one end of the micro-channel 1205, and the other end of the micro-channel 1205 extends to the sample inlet 1202 of the cover plate 1201, so that the liquid to be detected enters the detection region 1206 through the micro-channel 1205. For example, the centers of the calibration region 1207 and the centers of the detection regions 1206 are disposed on the same circumference at equal intervals, and the detection regions 1206 correspond to the photodetection units 1131 in the detection modules of the analyzer 1100 with the calibration regions 1207, respectively. The calibration area 1207 is used to detect the presence or absence of the test chip 1200 on the chip placement structure 1120 in the system calibration analyzer 1100.

For example, when the detection chip 1200 is placed on the chip placement structure 1120, the photodetection unit 1131 corresponding to the calibration area 1207 may receive the reflected light, so that the photodetection unit 1131 outputs an electrical signal, thereby determining that there is a detection chip 1200 in the analyzer 1100, and the control device may control the detection operations of other photodetection units 1131 according to the electrical signal; on the contrary, when the detecting chip 1200 is not placed on the chip placing structure 1120, the intensity of the reflected light received by the photodetecting unit 1131 corresponding to the calibration area 1207 is very weak, so that the photodetecting unit 1131 does not output an electric signal, and thus it is determined that the detecting chip 1200 is not present in the analyzer 1100 and the analyzer 1100 does not perform detection.

A test paper placement area 1208 is provided in the detection area 1206, and the test paper 1208 is placed in the test paper placement area 1208. And, the center department of detection zone 1206 sets up detection through-hole 1209, wait to detect that liquid takes place the color development reaction with test paper 1208 after getting into detection zone 1206, can observe the degree that the color development reaction goes on through detection through-hole 1209 to judge whether the current dropwise add wait to detect liquid evenly distributed in detection zone 1206, in addition, detection through-hole 1209 can also hold unnecessary liquid that waits.

For example, in some examples, as shown in fig. 12B, the detection zone 1206 of the detection chip 1200 is diamond shaped. For example, the detection zone 1206 may also be circular, elliptical, triangular, etc. The disclosed embodiments are not limited to the shape of the detection region 1206.

For example, in some examples, as shown in fig. 12A, the detection chip 1200 further includes a sample introduction unit 1204. For example, the sample injection unit has a through hole at a central position and is petal-shaped. The through hole of the sample injection unit 1204 is connected with the sample injection port 1202 of the cover plate 1201, the liquid to be detected is dripped into the sample injection unit 1204, and then the detection liquid enters the detection region 1206 of the detection chip through the micro-channel 1205 to perform a color reaction with the detection test paper 1208 through the sample injection port 1202 of the cover plate 1201.

For example, in other examples of embodiments, as shown in fig. 12C, the sample introduction unit 1204 can also be cylindrical. The embodiment of the present disclosure is not limited to the specific shape of the sample injection unit.

For example, in other examples, the number of detection regions 1206 may also be, for example, 2, 3, 4, 6, 7, etc., which are not limited in this disclosure.

For example, the calibration region 1207 in the detection chip is not necessary, and the detection chip may not be provided with the calibration region 1207. As shown in the example of fig. 12C, the detection chip includes 6 detection regions 1206 for which calibration regions 1207 have not been provided.

For example, in some examples, as shown in fig. 12C, a detection light passing hole 1210 is provided on a position of the substrate 1203 opposite to the detection through hole 1209 of the cover sheet 1202 to allow light emitted from the photodetecting unit 1131 in the analyzer 1100 to enter the detection chip 1200 and light reflected by the detection chip 1200 to be transmitted to the photodetecting unit 1131.

For example, in some examples, the substance content of the liquid is detected using an analyzer as shown in fig. 1A and 1B, the detection process including the steps shown in fig. 13.

Step S100: and dripping the liquid to be detected into the detection chip. After the liquid to be detected is uniformly distributed in the detection region 1206 and the color development reaction is completed, the detection chip 1200 may be subsequently placed into the analyzer 1100.

Step S200: and opening the first shell and the second shell and placing the detection chip. The opening distance between the second end 1194 of the first lock tongue 1183 and the second end 1195 of the second lock tongue 1184 is reduced (the second end 1194 of the first lock tongue 1183 and the second end 1195 of the second lock tongue 1184 are drawn together towards the middle of the first lock tongue and the second lock tongue 1184), the first end 1185 of the first lock tongue 1183 and the first end 1186 of the second lock tongue 1184 are separated from the buckle 1188 in a state of being buckled on the buckle 1188, so that the first shell 1110 and the second shell 1160 of the analyzer 1100 are opened, and the detection chip 1200 is placed in the chip placement structure 1120. The embodiment of the disclosure is not limited to the sequence of step S100 and step S200, for example, the liquid to be detected may be dropped into the detection chip 1200 after the detection chip 1200 is placed in the chip placing structure 1120, which is not limited herein.

Step S300: and closing the first shell and the second shell, and starting the analyzer for detection. The first casing 1110 and the second casing 1160 are closed, and then the micro switch 1305a is pressed for a long time, so that the analyzer 1100 starts to detect; the control device 1310 receives the detection result of the photodetection unit 1131 and transmits the detection result to the display device 1170.

Step S400: and obtaining a detection result. After the detection by the analyzer 1100 is completed, the detection result is viewed on the display screen by pressing the microswitch 1305b, and the detection result, for example, a detection report, may also be transmitted to another device via bluetooth (for example, the detection report is pushed to software or an applet used by the user).

Step S500: the detection chip is retrieved and the analyzer is turned off. The first casing 1110 and the second casing 1160 of the analyzer 1100 are opened again, the detection chip 1200 is taken out, the first casing 1110 and the second casing 1160 are closed, and the analyzer 1100 is turned off by pressing the microswitch 1305a for a short time.

Analyzer 1100 may enable simultaneous measurement of the contents of multiple substances of a liquid, such as breast milk, and the like, and show the results of the test in a relatively short period of time (e.g., 2-3 minutes). The analyzer 1100 has the advantages of simple structure, convenience in operation and the like, and can be used as a small-sized handheld household detection device, so that a user can complete the whole detection process at home, and can upload the detection result to a port of an application program (APP) installed on a mobile terminal such as a mobile phone in real time, thereby facilitating the analysis of the content of substances such as breast milk of the user, and providing professional nutrition, dietary guidance, clinical advice and the like according to the analysis result.

For the detection system and the analyzer in the above embodiments, since the detection module of the analyzer includes a plurality of photoelectric detection units or at least one photoelectric detection unit capable of rotating relatively, the analyzer can detect a plurality of detection areas of the detection chip respectively through the plurality of photoelectric detection units, so as to detect the contents of a plurality of substances in the liquid to be detected in the detection chip.

The following points need to be explained:

(1) the drawings of the embodiments of the disclosure only relate to the structures related to the embodiments of the disclosure, and other structures can refer to the common design.

(2) Without conflict, embodiments of the present disclosure and features of the embodiments may be combined with each other to arrive at new embodiments.

The above is only a specific embodiment of the present disclosure, but the scope of the present disclosure is not limited thereto, and any person skilled in the art can easily conceive of changes or substitutions within the technical scope of the present disclosure, and shall be covered by the scope of the present disclosure. Therefore, the protection scope of the present disclosure shall be subject to the protection scope of the claims.

Claims

1. An analyzer, comprising:

a first shell body which is provided with a first opening,

a chip placement structure disposed in the first housing for placing a detection chip, wherein the detection chip has at least one detection area, and

at least one detection unit disposed in the first housing,

wherein the at least one detection unit is configured to detect one or more detection areas of the detection chip, respectively, when the detection chip is placed on the chip placement structure.

2. The analyzer of claim 1, wherein the at least one detection unit comprises at least one photoelectric detection unit.

3. The analyzer as claimed in claim 2, wherein said at least one photodetecting unit each comprises at least one light emitting element and at least one photosensor device.

4. The analyzer of claim 3, further comprising:

and the optical path component is arranged between the chip placing structure and the detection unit in the first shell and is configured to transmit light emitted by the at least one light-emitting element to the chip placing structure and transmit light reflected by the detection chip placed on the chip placing structure to the at least one photoelectric sensing device.

5. The analyzer according to claim 4, wherein said optical path assembly comprises a light splitting disc, said light splitting disc comprises at least one set of light passing holes respectively corresponding to said at least one photo-detection unit,

each group of the at least one group of the light through holes comprises at least one light emitting through hole and at least one light reflecting through hole, the at least one light emitting through hole allows light emitted by at least one light emitting element of the corresponding photoelectric detection unit to pass through, and the at least one light reflecting through hole allows light reflected by a detection chip placed on the chip placement structure to pass through so as to be transmitted to at least one photoelectric sensing device of the corresponding photoelectric detection unit.

6. The analyzer of claim 5, wherein the side wall of the at least one light emitting through hole is beveled and the side wall of the at least one light reflecting through hole is beveled.

7. The analyzer according to claim 5, wherein said at least one photodetecting unit each comprises two light emitting elements and one photodetecting device, and said two light emitting elements are disposed on opposite sides of said one photodetecting device;

each group of the at least one group of the light through holes comprises two light emitting through holes and one light reflecting through hole, the two light emitting through holes are arranged on two opposite sides of the light reflecting through hole, and

the two light emitting through holes respectively allow light emitted by the two light emitting elements to pass through, and the one light reflecting through hole allows light reflected from a detection chip placed on the chip placement structure to pass through so as to be transmitted to the one photoelectric sensing device.

8. The analyzer of claim 7, further comprising:

a separation member disposed between the optical path member and the chip placement structure in the first housing,

wherein the separation member includes a light-transmitting portion configured to pass light emitted from the at least one light-emitting element and light reflected from the detection chip placed on the chip placement structure.

9. The analyzer according to claim 8, wherein the light-transmissive portion of the partition member comprises at least one transparent window respectively corresponding to the at least one detection unit to respectively allow passage of light emitted from the at least one light-emitting element of the corresponding photodetecting unit and light reflected from the detection chip placed on the chip placement structure to the at least one photodetecting device of the corresponding photodetecting unit.

10. The analyzer of claim 9, wherein the separation assembly further comprises a substrate and at least one transparent sheet,

the substrate includes at least one mounting through hole, and the at least one transparent sheet is embedded in the at least one mounting through hole to provide the at least one transparent window.

11. The analyzer of claim 8, further comprising:

a detection circuit board, on which the photoelectric detection unit is disposed, the detection circuit board including a first positioning hole,

the separating component comprises a positioning column and the light splitting disc comprises a second positioning hole, or the separating component comprises a second positioning hole and the light splitting disc comprises a positioning column,

the positioning column penetrates through the first positioning hole and the second positioning hole to connect the optical splitter disc, the separation assembly and the detection circuit board.

12. The analyzer of claim 1, wherein the first housing further comprises at least one support disposed at a bottom of the first housing to provide stable support to the first housing.

13. The analyzer according to any one of claims 1 to 10, further comprising a rotational drive device, wherein the at least one detection unit comprises one detection unit,

the rotation driving device is configured to drive the one detection unit to rotate relative to the chip placement structure.

14. The analyzer of claim 1, further comprising:

a second housing connected to the first housing,

the chip placing structure and the at least one detection unit are arranged in a space surrounded by the first shell and the second shell.

15. The analyzer of claim 14, wherein the second housing is hingedly connected to the first housing on a first side,

the second housing is configured to be closable with the first housing at a second side and to be opened to expose the chip placement structure,

the first side is disposed opposite the second side.

16. The analyzer of claim 15, wherein the first housing includes a first sub-opening and closing assembly disposed on the second side,

the second shell comprises a second sub-opening and closing component arranged on the second side,

wherein the first and second sub opening and closing members are configured to be coupled and separated from each other to respectively close and open the first and second housings to each other.

17. The analyzer of claim 16, wherein the second sub-opening and closing assembly includes an elongated first locking tab and an elongated second locking tab, the first locking tab and the second locking tab being arranged side-by-side in pairs,

the first sub-opening and closing component comprises a groove and a fastener, the fastener is positioned in the groove,

the first end part of the first bolt and the first end part of the second bolt are configured to extend into the groove and be buckled on the buckling piece so as to close the first shell and the second shell, and can be separated from the buckling piece so as to open the first shell and the second shell.

18. The analyzer of claim 17, wherein the second sub-opening and closing assembly further comprises a resilient member,

the elastic piece is arranged in the middle of the first lock tongue and the middle of the second lock tongue so as to elastically connect the first lock tongue and the second lock tongue, and is configured to exert elastic force so as to tend to enable the first lock tongue and the second lock tongue to be in a state of being capable of being buckled on the buckling piece.

19. The analyzer according to claim 18, wherein the elastic member is a torsion spring for applying an elastic force to bring the first end portion of the first locking tongue and the first end portion of the second locking tongue close to each other,

the second sub opening and closing assembly further comprises a switch, wherein the switch is connected with the first lock tongue and the second lock tongue and is configured to be operable so that the first end of the first lock tongue and the first end of the second lock tongue are separated from the fastener in a state of being fastened on the fastener.

20. The analyzer of claim 14, further comprising:

and a display device disposed on the second housing.

21. The analyzer of claim 20, further comprising:

at least one micro switch in signal connection with a display device and configured to control content displayed on the display device.

22. The analyzer of claim 20, further comprising:

a control device in signal connection with the detection unit and the display device, configured to receive a detection result of the detection unit and transmit the detection result to the display device, the display device configured to display the detection result.

23. A detection system, comprising:

the analyzer according to any one of claims 1 to 22,

a detection chip configured to be placeable on the chip placement structure of the analyzer.