CN209950078U - Airtight storehouse for animal experiments - Google Patents

Abstract

The utility model discloses an airtight chamber for animal experiments, which comprises a cuboid box body, wherein the cuboid box body comprises a bottom plate (1), a top plate (2), a front plate (3) and a rear plate (4) made of transparent materials and two side panels (5), characterized in that: one edge of the front panel (3) is connected with one of the side panels (5) through a hinge (6), and the other side of the front panel (3) The edge is connected with the other side panel (5) through a locking mechanism (7); the rear panel (4) or one of the side panels (5) is provided with an air inlet (12) and an air outlet ( 13); One of the side panels (5) is provided with an openable operation door (9), and the area of the operation door (9) is smaller than that of the front panel (3). Compared with the prior art, the utility model can provide a more stable atmospheric environment for animal experiments, and the atmospheric environment of the experimental animals will not fluctuate greatly when changing food, drinking water or checking individual animals; it is convenient for individual experiments. Animals are cared for or examined.

Description

An airtight chamber for animal experiments

technical field

The utility model relates to an airtight chamber for animal experiments, belonging to the technical field of animal experiment equipment.

Background technique

The animal model induced by hyperoxia/hypoxia is one of the commonly used animal modeling methods in experiments. It is necessary to provide a stable oxygen concentration environment for animal experimental subjects to observe the behavior of experimental animals, and to obtain experimental data by inspection and analysis of experimental animals. In the prior art, it is a common method to use a transparent box as an airtight chamber to raise experimental animals. An appropriate amount of oxygen can be injected into the airtight chamber to maintain a set oxygen concentration, and experimental animals (such as experimental mice) are placed In an independent ventilation cage, multiple ventilation cages may be placed in a transparent box at the same time; and the box body only has a large openable and closable door for the insertion and removal of ventilation cages. However, when changing food, drinking water or checking individual animals during the experiment, the door of the box must be opened, resulting in large fluctuations in the oxygen concentration in the box, which affects the experiment, especially whether it is sensitive to oxygen concentration. Frequently opening and closing the door of the box will bring invaluable variables to the experiment, and even lead to the failure of the experiment.

Utility model content

In order to solve the problems existing in the prior art and avoid large fluctuations in the atmospheric environment of experimental animals when changing food and drinking water or inspecting individual animals, the utility model provides an airtight chamber for animal experiments. The specific technical scheme is as follows .

An airtight warehouse for animal experiments, comprising a cuboid box body, the cuboid box body comprising a bottom plate, a top plate, a front plate, a rear plate and two side plates made of transparent materials, characterized in that: one edge of the front plate is It is connected with one of the side panels through a hinge, and the other edge of the front panel is connected with the other side panel through a locking mechanism; the rear panel or one of the side panels is provided with an air inlet and a An air outlet; one of the side panels is provided with an openable operation door, and the area of the operation door is smaller than that of the front panel.

Further, a circular through hole is opened on the side plate, a cylindrical member is fixedly arranged on the outer surface of the side plate, one end of the cylindrical member covers the through hole, and the other end passes through the hinge. The operation door is mounted on the locking mechanism, and the operation door has a circular shape and can cover the cylindrical member.

Further, a flexible sealing member is arranged in the through hole or the cylindrical member, the sealing member is arranged concentrically with the cylindrical member, and the sealing member has a plurality of divergent gaps.

Further, a horizontal partition is arranged in the cuboid box, and the horizontal partition is also made of transparent material and has a plurality of ventilation holes; the horizontal partition divides the inner space of the cuboid box into two or more. A cavity; the side plate is provided with the corresponding operating door corresponding to each of the cavities.

Further, the air inlet and the air outlet are arranged corresponding to different cavities.

Further, a sealing strip is provided at the connection between the front panel and the top panel, the bottom panel and the side panel.

Further, a sealing strip is provided at the connection between the operation door and the cylindrical part.

Compared with the prior art, the utility model can provide a more stable atmospheric environment for animal experiments, and the atmospheric environment of experimental animals will not fluctuate greatly when food, drinking water is replaced or individual animals are inspected; it is convenient for individual experiments. Animals are cared for or examined.

Description of drawings

Fig. 1 is the three-dimensional schematic diagram of the closed chamber for animal experiments of the present invention;

Fig. 2 is another perspective three-dimensional schematic diagram of the closed chamber for animal experiments of the present invention;

Fig. 3 is the top perspective schematic diagram of the airtight chamber for animal experiments of the present invention;

FIG. 4 is a schematic plan view of the closed chamber for animal experiments of the present invention (viewed from the rear side to the front side).

In the figure: bottom plate 1, top plate 2, front panel 3, rear panel 4, side panel 5, hinge 6, locking mechanism 7, cylindrical part 8, operating door 9, seal 10, horizontal partition 11, air inlet 12. Air outlet 13.

Detailed ways

The present utility model will be described in further detail below in conjunction with the accompanying drawings.

Referring to the accompanying drawings 1-4, the airtight chamber for animal experiments includes a cuboid box body, and the cuboid box body includes a bottom plate 1, a top plate 2, a front plate 3, a rear plate 4 and two side plates 5 made of transparent materials (such as plexiglass), One edge of the front panel 3 is connected to one of the side panels 5 through a hinge 6 , and the other edge of the front panel 3 is connected to the other side panel 5 through a locking mechanism 7 . When the front panel 3 is in the closed position, the front panel 3 is locked to achieve a sealing effect, and a sealing strip (not shown) is provided at the connection between the front panel 3 and the top panel 2 , the bottom panel 1 and the side panel 5 to improve the sealing performance ; The rear panel 4 is provided with the air inlet 12 and the air outlet 13, of course the air inlet 12 and/or the air outlet 13 can also be opened on the side plate 5, and the air inlet is connected with the air storage tank, and the valve is used to control the storage. The gas supply of the gas tank, the gas storage tank can be an oxygen tank, a nitrogen tank, etc., which can be selected according to the specific experimental purpose. The air outlet 13 can be directly connected to the atmospheric environment, and can also be connected to other collection devices.

The side plate 5 is provided with a circular through hole, the size of which is sufficient for a single arm to pass through. A cylindrical part 8 is fixed on the outer surface of the side plate 5, and the cylindrical part 8 is also made of transparent material. The outer surface of the side plate 5 can be fixed by gluing, one end of the cylindrical member 8 covers the through hole, and the other end is provided with an openable and closable operating door 9 through the hinge 6 and the locking mechanism 7. The door 9 has a circular shape and can cover the cylindrical member 8 , and the area of the operation door 9 is smaller than that of the front panel 3 . A weather strip is also provided at the connection between the operation door 9 and the cylindrical member 8 . The operating door 9 is arranged on the cylindrical member instead of being directly installed on the side panel 5, which can avoid damage to the side panel 5, improve the stability of the side panel 5, and make the structure of the entire cuboid box more reliable.

Preferably, a flexible sealing member 10 is provided in the through hole or the cylindrical member 8 , the sealing member 10 is arranged concentrically with the cylindrical member 8 , and the sealing member 10 has a plurality of divergent gaps. The sealing member 10 can be made of rubber with a certain hardness. When the arm passes through, the sealing member bends and fits the arm, which can effectively prevent a large amount of gas in the rectangular box from escaping from the operating door 9, and prevent the atmosphere of the box from becoming large. Amplitude fluctuations.

Preferably, a horizontal partition 11 is provided in the cuboid box, and the horizontal partition 11 is also made of transparent material and is provided with a plurality of ventilation holes; the horizontal partition 11 divides the inner space of the cuboid box into more than two cavities; The side plate 5 is provided with a corresponding operating door 9 corresponding to each cavity. A ventilation cage containing experimental animals can be placed in each cavity, and the ventilation holes can ensure that the gas composition in each cavity is approximately the same. Preferably, the air inlet 12 and the air outlet 13 are arranged corresponding to different cavities, which is beneficial to improve the uniformity of gas components in each cavity in the rectangular box.

The use method of the utility model is as follows: at the beginning of the experiment, open the front panel 3, put the ventilation cage containing the experimental animals into the cuboid box, close the front panel 3 and use the locking mechanism 7 to lock the front panel; open the storage The valve of the gas tank adjusts the gas composition in the cuboid box. For example, the oxygen concentration in the box can be adjusted to 75% through the oxygen tank and maintained in a stable state. A detection device can be placed in the box to monitor the gas concentration. When it is necessary to provide food or drinking water to the experimental animals, open the operation door 9, and send the food or drinking water into the designated ventilation cage through the through holes of the side plate 5. When it is necessary to inspect individual animals, it can also be operated by operating The door 9 proceeds without opening the front panel 3 . Since the area of the operation door (through hole of the side panel) is much smaller than that of the front panel, the stability of the gas composition in the box can be better maintained during the above operation. If the sealing member 10 is provided, the sealing member 10 can also fit the arm, which further prevents the large fluctuation of the atmospheric environment in the box.

Through comparison, it is found that when the oxygen concentration in the box is maintained at 75%, the front panel 3 is opened for one minute and the oxygen concentration will be reduced from 75% to about 30%, but if the operation door 9 is opened separately for operation If so, the fluctuation range of the oxygen concentration is generally not more than 20%.

The embodiments of the present invention have been described above with reference to the accompanying drawings, and the embodiments of the present invention and the features of the embodiments may be combined with each other without conflict. The present invention is not limited to the above-mentioned specific embodiments, and the above-mentioned specific embodiments are only illustrative, rather than limiting, and those of ordinary skill in the art, under the inspiration of the present invention, do not deviate from the present invention. Under the protection scope of the purpose and the claims, many forms can also be made, which all belong to the protection scope of the present invention.

Claims (7)

1. An airtight warehouse for animal experiments, comprising a cuboid box comprising a bottom plate (1), a top plate (2), a front panel (3), a rear panel (4) and two transparent materials using a transparent material. A side panel (5), characterized in that: one edge of the front panel (3) is connected to one of the side panels (5) through a hinge (6), and the other edge of the front panel (3) is locked by a hinge (6). The buckle mechanism (7) is connected with the other side panel (5); the rear panel (4) or one of the side panels (5) is provided with an air inlet (12) and an air outlet (13); One of the side panels (5) is provided with an openable operation door (9), and the area of the operation door (9) is smaller than that of the front panel (3). 2. A kind of airtight warehouse for animal experiment according to claim 1, is characterized in that, described side plate (5) is provided with a circular through hole, and the outer surface of described side plate (5) is fixed A cylindrical part (8) is provided, one end of the cylindrical part (8) covers the through hole, and the other end is provided with the operating door (9) through a hinge (6) and a locking mechanism (7), The operating door (9) has a circular shape and can cover the cylindrical member (8). 3. A kind of airtight chamber for animal experiments according to claim 2, characterized in that, a flexible seal (10) is provided in the through hole or the cylindrical part (8), and the seal ( 10) Concentrically arranged with the cylindrical part (8), the sealing element (10) has a plurality of divergent slits. 4. A kind of airtight warehouse for animal experiment according to claim 1, is characterized in that, described cuboid box body is provided with horizontal partition plate (11), described horizontal partition plate (11) also adopts transparent material and is provided with a plurality of ventilation holes; the horizontal partition plate (11) divides the inner space of the cuboid box into more than two cavities; the side plate (5) is provided with corresponding cavities corresponding to each of the cavities The operating door (9). 5 . The airtight chamber for animal experiments according to claim 4 , wherein the air inlet ( 12 ) and the air outlet ( 13 ) are arranged corresponding to different cavities. 6 . 6. A kind of airtight warehouse for animal experiment according to claim 1, is characterized in that, the junction of described front panel (3) and described top panel (2), bottom panel (1) and side panel (5) is set Has seals. 7 . The airtight chamber for animal experiments according to claim 2 , wherein a sealing strip is provided at the connection between the operation door ( 9 ) and the cylindrical part ( 8 ). 8 .

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