CN207506855U - For the superconducting intense magnetic field device of oncotherapy - Google Patents
For the superconducting intense magnetic field device of oncotherapy Download PDFInfo
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- CN207506855U CN207506855U CN201720478334.9U CN201720478334U CN207506855U CN 207506855 U CN207506855 U CN 207506855U CN 201720478334 U CN201720478334 U CN 201720478334U CN 207506855 U CN207506855 U CN 207506855U
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Abstract
The utility model provides a kind of superconducting intense magnetic field device for oncotherapy, the field generating unit of the intensity controlled high-intensity magnetic field with direction is generated including therapeutic bed, on the human body towards therapeutic bed, for controlling the controller of field generating unit and supporting field generating unit and drive field generating unit relative to therapeutic bed movement to adjust the rack in high-intensity magnetic field direction, field generating unit is electrical connected with controller.The utility model is by setting field generating unit, field generating unit is controlled to generate high-intensity magnetic field using controller, field generating unit is supported by rack, and field generating unit is allow to be moved relative to therapeutic bed, and then can adjust field generating unit generation high-intensity magnetic field direction and position, with constraint delivering drug range；And pass through the relative movement of field generating unit and therapeutic bed, make the high-intensity magnetic field that field generating unit generates that drug be guided to be trapped to the targeting of specific tumors position range, and realize efficient, accurate target administration.
Description
Technical field
The utility model belongs to high-intensity magnetic field field, is to be related to a kind of strong magnetic of the superconduction for oncotherapy more specifically
Field device.
Background technology
Tumour be body under the action of one or more carcinogenic factors, certain class cell of local organization is lost to growth
Normal regulation, lead to lesions position paraplasm and formed.In recent years, directly with or in conjunction with physical/chemical factor target
To the proposition of the researchs such as tumor focus, the new way of great potential is provided for oncotherapy.
High-intensity magnetic field is a kind of special artificial physics environment.With the development of superconductor science and technology, based superconductive
The high-intensity magnetic field manufacturing technology of technology is also able to fast development, and is applied in scientific research, industrial production and health medical treatment.
As a kind of physical field for being distributed in three dimensions, the Noninvasive to body is it in health medical treatment application in magnetic field
When unique advantage.The fuel factor and specific magnetic fields guiding paramagnetic meterial that magnetic field generates under given conditions are targeted in vivo
Ability provide new departure for oncotherapy.In recent years, superparamagnetic iron oxide nano particle (Super-paramagnetic
Iron oxide nanoparticles, SPIONs) appearance and application the targeted therapy based on magnetic field has quickly been pushed to study.
The research in the field at present is concentrated on controls sensitive media to carry out drug targeting delivering, and then intervene lesion by magnetic field
Treatment.
Ferro element is the highest trace element of human body in-vivo content, internal " iron metabolism " and neural, immune, blood and bone
It is closely related etc. multiple system functions, it is reduced with neurodegenerative disease, immunity and the disease relationships such as bone-loss is close.Iron
The tumour cell " procedural iron is dead " that element participates in is also new by one kind of the periodicals and magazines such as Cell, Nature report in recent years
" cell death " pattern.In view of the potential application of " iron is dead " in cancer cell, tumor suppression is removed, utilizes high-intensity magnetic field pair
The adjustment effect of " iron metabolism " reaches the treatment and regulation and control of the diseases such as tumour, becomes a kind of new strategy.Promoting tumour cell
In the means of iron death, including the two kinds of selections of tumour cell feature target administration and knub position range target administration；It is but current
In confirmable tumour cell feature, cell characteristic has no the target-seeking feature that can be identified with normal cell.Therefore this is just needed
A kind of equipment can generate high-intensity magnetic field and drug be guided to be trapped to the targeting of specific tumors position range by the high-intensity magnetic field, such as
The drugs such as iron preparation and small molecule erastin, the small molecule RSL3 that can cause induction cell iron death are imported into tumor locus,
It is killed by by way of iron death except tumour cell, meanwhile, the hazard boundary of drug is constrained, and adjust the concentration of drug, with reality
Now accurate controllable treatment tumour.
Utility model content
The purpose of this utility model is to provide a kind of superconducting intense magnetic field device for oncotherapy, to solve existing skill
The problem of can not accomplishing efficient, accurate target administration present in art in oncotherapy.
To achieve the above object, the technical solution adopted in the utility model is：A kind of superconduction for oncotherapy is provided
High-intensity magnetic field device, including be used to support human body therapeutic bed, for towards generate on the human body of the therapeutic bed it is intensity controlled with
The high-intensity magnetic field in direction with realize target administration field generating unit, for controlling the controller of the field generating unit and branch
It supports the field generating unit and drives the field generating unit relative to the therapeutic bed movement to adjust the high-intensity magnetic field
The rack in direction, the field generating unit are electrical connected with the controller.
Further, combination or superconducting coil of the field generating unit by superconducting coil, superconducting coil and permanent magnet
Combination with electromagnetic coil is formed.
Further, the superconducting coil is two, and two superconducting coils settings in X-shaped, V-arrangement, cross or
Axially opposed shape.
Further, the shape of the superconducting coil for aciculiform, frustro-pyramidal, cylinder, square column type, annular, Crossed Circle,
Helical annular, double helix are annular, side is annular, both sides are annular, any one or a few shape in square helical annular, both sides' helical annular
The combination of shape.
Further, the current range of the superconducting coil is 0-500A, the magnetic induction intensity of the superconducting coil generation
Ranging from 1-50T.
Further, the field generating unit includes two for coordinating the circle of generation gradient magnetic or ellipse super
Loop, each superconducting coil is supported horizontally inside in the rack, and the horizontal axis pair of two superconducting coils is set
It puts, stationary magnetic field is formed between two superconducting coils, the outside of each superconducting coil forms the gradient magnetic of intensity diminuendo
.
Further, the field generating unit includes two circles for generating focusing magnetic field or oval superconducting line
Circle, two superconducting coils intersect in X shapes or V-type is arranged in a crossed manner.
Further, the field generating unit includes being relatively arranged on two superconductions of the therapeutic bed top and lower section
Coil, each superconducting coil are in spiral form.
Further, each superconducting coil is in solenoidal structure, and each superconducting coil is provided centrally with magnetic core, each institute
It states magnetic core and stretches out the corresponding superconducting coil to form probe, strengthened magnetic field accumulation regions are formed between two probes
Gradient magnetic area is formed with the periphery of two probes.
Further, the sensor for monitoring magnetic induction intensity is further included, the sensor and the controller are electrical
It is connected, the sensor is installed in the therapeutic bed.
The advantageous effect of superconducting intense magnetic field device provided by the utility model for oncotherapy is：With the prior art
It compares, the utility model is set by setting field generating unit, field generating unit is controlled to generate strong magnetic using controller
, field generating unit is supported, and field generating unit is allow to be moved relative to therapeutic bed by rack, and then can adjust
Save field generating unit generate high-intensity magnetic field direction and position, with constraint delivering drug range；And it is sent out by magnetic field
The relative movement of raw unit and therapeutic bed makes the high-intensity magnetic field that field generating unit generates guide drug to specific tumors position range
Targeting traps, and realizes efficient, accurate target administration.
Description of the drawings
It, below will be to embodiment or the prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
Attached drawing is briefly described needed in description, it should be apparent that, the accompanying drawings in the following description is only that this practicality is new
Some embodiments of type, for those of ordinary skill in the art, without having to pay creative labor, can be with
Other attached drawings are obtained according to these attached drawings.
Fig. 1 is the structural representation of the superconducting intense magnetic field device for oncotherapy that the utility model embodiment one provides
Figure；
Fig. 2 is the structural representation of the superconducting intense magnetic field device for oncotherapy that the utility model embodiment two provides
Figure；
Fig. 3 is the structural representation of the superconducting intense magnetic field device for oncotherapy that the utility model embodiment three provides
Figure；
Fig. 4 is the structural representation of the superconducting intense magnetic field device for oncotherapy that the utility model embodiment four provides
Figure；
Fig. 5 is the structural representation of the superconducting intense magnetic field device for oncotherapy that the utility model embodiment five provides
Figure.
Specific embodiment
In order to which technical problem to be solved in the utility model, technical solution and advantageous effect is more clearly understood, with
Lower combination accompanying drawings and embodiments, the present invention is further described in detail.It should be appreciated that specific reality described herein
It applies example to be only used to explain the utility model, is not used to limit the utility model.
It should be noted that when element is referred to as " being fixed on " or " being set to " another element, it can be directly another
On one element or it is connected on another element.When an element is known as " being connected to " another element, it can
To be directly to another element or be indirectly connected on another element.Term " installation ", " connected ", " connection " are answered
It is interpreted broadly, for example, it may be being fixedly connected or being detachably connected or be integrally connected；Can be that machinery connects
It connects or is electrically connected；It can be directly connected, can also be indirectly connected by intermediary, can be in two elements
The connection in portion or the interaction relationship of two elements.It for the ordinary skill in the art, can be according to specific feelings
Condition understands concrete meaning of the above-mentioned term in the utility model.
It is to be appreciated that term " length ", " width ", " on ", " under ", "front", "rear", "left", "right", " vertical ",
The orientation or position relationship of the instructions such as " level ", " top ", " bottom " " interior ", " outer " are to be closed based on orientation shown in the drawings or position
System is for only for ease of description the utility model and simplifies description rather than instruction or imply that signified device or element are necessary
With specific orientation, with specific azimuth configuration and operation, therefore it is not intended that limitation to the utility model.
In addition, term " first ", " second " are only used for description purpose, and it is not intended that instruction or hint relative importance
Or the implicit quantity for indicating indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more this feature." multiple " are meant that two or two in the description of the present invention,
More than, unless otherwise specifically defined.
The utility model provides a kind of superconducting intense magnetic field device for oncotherapy, the treatment including being used to support human body
Bed, for realizing that the magnetic field of target administration is sent out towards the intensity controlled high-intensity magnetic field with direction is generated on the human body of the therapeutic bed
Raw unit, for controlling the controller of the field generating unit and the support field generating unit and the magnetic field driven to send out
Unit is given birth to relative to the therapeutic bed movement to adjust the rack in the high-intensity magnetic field direction, the field generating unit and the control
Device processed is electrical connected.The advantageous effect of superconducting intense magnetic field device provided by the utility model for oncotherapy is：With showing
There is technology to compare, the utility model is set by setting field generating unit, field generating unit is controlled to produce using controller
Raw high-intensity magnetic field, field generating unit is supported, and field generating unit is allow to be moved relative to therapeutic bed by rack, and then
Can adjust field generating unit generation high-intensity magnetic field direction and position, with constraint delivering drug range；And pass through
The relative movement of field generating unit and therapeutic bed makes the high-intensity magnetic field that field generating unit generates be lured the drug for injecting body
Dense poly-, enrichment is led, and is constrained in that human body is in need for the treatment of to have made a definite diagnosis position, local cells is caused to reach the death of apoptotic iron
Physiological requirement, so as to cause the death of a little cell of tumour cell and periphery, realize efficient, accurate target administration.
The superconducting intense magnetic field device for oncotherapy of the utility model be primarily adapted for use in fixed position, it is diagnosable determine
Range, periphery have the healthy area of encroaching on of enough ranges, such as osteosarcoma, leukaemia, most skin tumour, internal organs swell
Knurl, lympha tumour, body of gland tumour etc..
Now illustrated to provided by the utility model for the superconducting intense magnetic field device of oncotherapy.
Embodiment one：
Referring to Fig. 1, the superconducting intense magnetic field device for oncotherapy of the present embodiment, occurs including therapeutic bed, magnetic field
Unit, controller 15 and rack；Therapeutic bed is used to support human body, when being treated, to lie in therapeutic bed for patient
On, and then oncotherapy conveniently is carried out to patient.Field generating unit makes magnetic field towards in therapeutic bed for generating high-intensity magnetic field,
And field generating unit is electrical connected with controller 15, so as to field generating unit be controlled to generate by controller 15
The intensity in magnetic field, to realize that magnetic field intensity is adjusted；Field generating unit is mounted in rack, can support magnetic by rack
Field generating unit, while field generating unit can be made to be moved relative to therapeutic bed, and then field generating unit can be set to produce
The direction of raw position, and make magnetic field towards the specific position of patient in therapeutic bed, and then guide drug to specific tumors position model
It encloses targeting to trap, constrains the range of drug, and adjust the concentration of drug, to realize precisely controllable treatment tumour.
By setting field generating unit, field generating unit is controlled to generate high-intensity magnetic field using controller 15, pass through machine
Frame supports field generating unit, and field generating unit is allow to be moved relative to therapeutic bed, and then can adjust magnetic field hair
The direction and position of high-intensity magnetic field that raw unit generates, to constrain the range of drug；And pass through field generating unit and therapeutic bed
Relative movement, make the high-intensity magnetic field that field generating unit generates that drug be guided to be trapped to the targeting of specific tumors position range, and real
Now efficient, accurate target administration.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, field generating unit is made of superconducting coil 1.Using superconducting coil 1, stronger magnetic field can be generated, in order to draw
Drug is led to trap, and constrain the range of drug to the targeting of specific tumors position range.Certainly, in other embodiments, magnetic field is sent out
Raw unit can also use superconducting coil 1 and the combination of permanent magnet to form.In further embodiments, field generating unit can be with
It is formed using the combination of superconducting coil 1 and electromagnetic coil, which can use common electromagnetic coil.
Further, the superconducting magnet that superconducting coil 1 can use low-temperature superconducting and high-temperature superconductor is main material making,
It can generate magnetic field intensity ranging from 1-50T (T be unit of magnetic field strength, tesla).And permanent magnet can be used with rare earth
Moderate strength kicker magnet of the permanent magnet for main material, magnetic field intensity ranging from 0.4-1T.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, field generating unit includes two superconducting coils 1, and each superconducting coil 1 is rounded, and two superconducting coils 1 intersect in X shapes
Setting.Two superconducting coils 1 of the structure can generate focusing magnetic field, and magnetic field is focused on to the certain bits of patient in therapeutic bed
It puts, and then drug is guided to be trapped, and constrain the range of drug to the targeting of specific tumors position range.Two superconducting coils of the structure
1 is arranged in a crossed manner in X shapes, and the crosspoint of two superconducting coils 1 is the two of the corresponding vertical direction of two superconducting coils, 1 center of circle coincidence point
End.
Further, two superconducting coils 1 are rotated around its vertical axes, so that the magnetic field generated to field generating unit focuses on
The position of point is finely adjusted.Further, the rotary speed of superconducting coil 1 is less than 5 degrees seconds, to be preferably adjusted.Two
When superconducting coil 1 rotates, portion space incorporated therein generates the accumulated time in magnetic field, in two superconducting lines that X shapes are arranged in a crossed manner
The horizontal axis of circle 1 forms weakest magnetic field area, and vertical direction forms the stronger area in magnetic field, and intersecting axle region forms magnetic field most
Strong area, and then form limited magnetic field aggregation.
Further, 60-80cm of each superconducting coil 1, make superconducting coil 1 be sleeved in therapeutic bed.So that human body can be from
Pass through in superconducting coil 1.Two groups of superconducting coils 1 pass to the same direction, same intensity electric current, overlap two superconducting coils 1
Axis at magnetic field intensity it is most strong.It is also convenient for controlling simultaneously.
Further, in other embodiments, each superconducting coil 1 can also be oval.Further, ellipse is super
The major diameter of loop 1 ranging from 60-80cm, so that human body can pass through, short axle is directly 40-60cm, so as to superconducting line
Circle 1 improves the magnetic field intensity for focusing on human body specific position closer to human body.
In other embodiments, two superconducting coils 1 can also set the shapes such as V-shaped, cross or axially opposed shape.
In other embodiments, the shape of each superconducting coil 1 can be aciculiform, frustro-pyramidal, cylinder, square column type, ring
Shape, Crossed Circle, helical annular, double helix are annular, side is annular, both sides are annular, any one in square helical annular, both sides' helical annular
The combination of kind or several shapes.As field generating unit can be by superconducting coil 1, the combination of superconducting coil 1 and permanent magnet or super
Loop 1 and the combination of general solenoid are formed；And field generating unit can be formed by aciculiform, frustro-pyramidal, cylinder
It is the block structures such as shape, square column type and annular, Crossed Circle, helical annular, double helix annular or the side's annular thus deformed, double
The superconducting coil 1 of square annular, square helical annular, both sides' helical annular and these shapes is composed.It is controllable to generate
The gradient magnetic in magnetic field intensity and direction, aggregation magnetic field etc..
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, the current range of superconducting coil 1 is 0-500A, the magnetic induction intensity ranging from 1-50T that superconducting coil 1 generates.So as to
Preferably guiding drug traps, and constrain the range of drug to the targeting of specific tumors position range.Preferably, each superconducting coil 1
Electric current for 250-500A, to ensure that the magnetic field intensity generated is stronger.Preferably, the magnetic field intensity model that field generating unit generates
It encloses for 3-50T.
Further, 1 material therefor of superconducting coil can be first generation bismuth system, niobium system or second generation yttrium series superconducting material material
Material and other superconductors are made.Preferably, superconducting coil 1 uses first generation bismuth system, niobium series superconducting material or second generation yttrium
Series superconducting material.Further, first generation niobium series superconducting material can be used.In addition, further, superconducting coil 1 can be with
Using superconducting wire, it is entwined in a manner of parallel arrangement mode and stacked arrangement.Superconducting coil 1 winds the number of turn and arrangement mode
It is steady magnetic field, gradient magnetic or pulsed magnetic field to determine to expose in magnetic area.1 current range of superconducting coil is 0-500A, preferably electric
Stream magnitude range is 250-500A.Utilize the producible magnetic induction intensity of the superconductor ranging from magnetic field of 0.4-50T；It is preferred that
Magnetic field intensity ranging from 3-50T, further preferably 3-16T.Magnetic induction intensity passes through the size of current in control coil and side
To control.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, controller 15 includes bed controller, field controller and server, and bed controller is used to control therapeutic bed opposite
In the position of field generating unit, can specifically be realized with shifting magnetic field generating unit or Mobile treatment table.Field controller is used
Intensity, frequency, direction and angle in control magnetic field are lured so that guiding drug is better achieved to the targeting of specific tumors position range
Collection, constraint.Server is used for centralized Control, monitoring and operation.
Further, server includes data storage, central processing unit and touching-type monitor, operation keyboard, mouse
Mark.Data storage is used to store patient information, the treatment bed position information of acquisition, magnetic field environment data；Central processing unit is used
It is handled in above-mentioned data；Touching-type monitor is used to show the magnetic induction intensity parameter that magnetic field sensor measures, and square
Convenient to operate person carries out intuitive operation；Keyboard and mouse are used for the operation and control of controller 15.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, which further includes the sensor 5 for monitoring magnetic induction intensity, sensor
5 are electrical connected with controller 15, and sensor 5 is mounted in therapeutic bed.Specifically, in the present embodiment, therapeutic bed includes bed body 4,
Sensor 5 for monitoring magnetic induction intensity in bed body 4 is installed, sensor 5 in bed body 4 is set, magnetic can be monitored in real time
The magnetic field intensity that field generating unit generates, and timely feedback to controller 15, and then facilitate and controlled.
Further, therapeutic bed can use the metal materials such as stainless steel, copper, aluminium, timber, high molecular material, natural fibre
The nonferromugnetic materials such as material or man-made fibre material are tieed up to form.
Further, in the present embodiment, therapeutic bed further includes socle, is supported bed body 4 on the ground by socle.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, rack includes the supporting rod 10 of two truss 7,11 of two truss 7,11 and connection.Field generating unit includes two
Superconducting coil 1, and it is arranged in a crossed manner in X, it is formed and intersects Crossed Circle.Two infalls of two superconducting coils 1 use first respectively
Shaft 3 is slidably mounted on two truss 7,11, so that the field generating unit is allow to be moved on truss 7,11, so that it is opposite
It is moved forward and backward in therapeutic bed.
Further, two infalls of two superconducting coils 1 are separately mounted to the second shaft 2, and the second shaft 2 is articulated in
In first rotating shaft 3, and then two superconducting coils 1 is allow to be rotated around vertical axis low speed small angle range, by high magnetic field area
Two annulus superconducting coils, 1 crossing center position is focused on, and then realizes that the tumour of human body specific position exposes magnetic treatment and targets super
The targeted delivery of paramagnetic drug.
Further, two truss 7,11 are separately installed with sliding rail 6,12, to guide field generating unit in machine well
It is moved on frame.Further, the both ends of each supporting rod 10 are connected respectively by 8,13 and two truss of connector 7,11, with side
Just it connects.
Further, in the present embodiment, field generating unit is one, in other embodiments, field generating unit
It can be multiple, such as two or three are arranged side by side and goes up.
In other embodiments, bed body 4 can also be supported, and transmission mechanism and power are installed on bedstead using bedstead
Mechanism by actuating unit drive transmission device, drives bed body 4 to be moved forward and backward on bedstead, and then realizes bed body 4 relative to magnetic
Field generating unit moves.Transmission mechanism is to conduct the rotating torque of power section and semaphore request is controlled to carry out by controller 15
Conversion, so that bedstead can carry out three-dimensional movement.Specifically, transmission mechanism can use worm gear mechanism, gear mechanism, gas
The mechanism of the power transmitting elements such as motivation structure and guide assembly composition；Power section is far from therapeutic bed and field generating unit
Magnetic screen can control variable-speed motor, and effect is the control requirement by controller 15 to driveline output torque power.
Specifically, in the present embodiment, the superconducting coil 1 of field generating unit is (maximum using first generation niobium series superconducting material
Electric current 500A, Western Supercomducing Technologies Co., Ltd.) coiling forms.Superconducting coil 1 is two, and each superconducting coil 1 is in
Annular；And two superconducting coils 1 coiling in a manner of intersecting concentric circles using superconducting tape, in each superconducting coil 1 of coiling
Aperture is 60-80cm, and is mounted in first rotating shaft by the second shaft, and first rotating shaft is slidably mounted on the sliding rail of rack
On, so that field generating unit can rotate, and can be moved along sliding rail around vertical axis low speed small angle range.In use, people
Body can lie on the back in therapeutic bed, and therapeutic bed is located in intersection Crossed Circle field generating unit, and field generating unit is moved along sliding rail
It is dynamic, and then moved back and forth along the long axis direction of therapeutic bed, with the different location of targeting fixed point human body.What field generating unit generated
Magnetic induction intensity is measured by the magnetic induction intensity sensor 5 (SAV01, the micro- magnetic science and technology in Yichang east) being fixed in therapeutic bed,
And monitoring data are fed back into controller 15.Controller 15 includes field controller (MDA-3, Britain CT), data storage
(ZLKCFM100, Zhuo Lekang), central processing unit (IPC-610-L-H-G-MB, Advantech), display panel (T104XGA,
TKUN) and magnetic field controls operation console (such as keyboard, mouse component).Control operation console that patient information is inputted center by magnetic field
Then processor is preserved by data transmission to data storage.Control operation console input in magnetic field needs to generate the parameter in magnetic field,
Magnetic field parameter is monitored by magnetic field sensor 5 and transfers data to data storage and display panel, data acquisition unit acquisition
Information pass through data transmission to data storage.
Embodiment two：
Referring to Fig. 2, the superconducting intense magnetic field device for oncotherapy of the present embodiment and embodiment one are used for tumour
The superconducting intense magnetic field device for the treatment of is distinguished as：
The field generating unit of the superconducting intense magnetic field device for oncotherapy of the present embodiment includes two superconducting coils
1, two superconducting coils 1 generate gradient magnetic for coordinating.Each superconducting coil 1 is rounded, and each superconducting coil 1 is supported horizontally inside
In rack 25, and the horizontal axis of two superconducting coils 1 forms stationary magnetic field, each superconduction to setting between two superconducting coils 1
The outside of coil 1 forms the gradient magnetic of intensity diminuendo.Specifying in the stronger region in magnetic field, in therapeutic bed patient's is specific
Position, and then drug is guided to be trapped, and constrain the range of drug to the targeting of specific tumors position range.
Further, 60-80cm of each superconducting coil 1, make superconducting coil 1 be sleeved in therapeutic bed.So that human body can be from
Pass through in superconducting coil 1.Two groups of superconducting coils 1 pass to the same direction, same intensity electric current, also, between two superconducting coils 1
Away from for 1-20cm.Make to form most strong steady magnetic field between two superconducting coils 1, two 1 outsides of superconducting coil then form diminuendo
Gradient magnetic；It is also convenient for controlling simultaneously.
Further, in other embodiments, each superconducting coil 1 can also be oval.Further, ellipse is super
The major diameter of loop 1 ranging from 60-80cm, so that human body can pass through, short axle is directly 40-60cm, so as to superconducting line
Circle 1 improves the magnetic field intensity for focusing on human body specific position closer to human body.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, rack 25 is in frame shape, and rack 25 includes two longerons at two crossbeam both ends of two crossbeams and connection.
Field generating unit includes two superconducting coils 1, and arranged in a crossed manner in X, is formed and intersects Crossed Circle.Two superconducting lines
The line of two infalls of circle 1 is horizontal, and two infalls of two superconducting coils 1 use first turn respectively
Axis 21 is slidably mounted on two crossbeams, so that the field generating unit is allow to be moved on crossbeam, and then relative to treatment
Bed is moved forward and backward.Further, two crossbeams are separately installed with sliding rail 22, to guide field generating unit well in rack 25
Upper movement.
Further, in the present embodiment, the both ends of the bed body 4 of therapeutic bed are rack-mount by support shaft 23 respectively,
To support therapeutic bed by stent.Further, the middle part of each longeron of rack 25 is mounted on stent by bearing 24
On, so as to be rotated on stent around trunnion axis, and then field generating unit is driven to be swung around trunnion axis.Further, bed
Sensor 5 on body 4 is installed, to monitor the magnetic field intensity of field generating unit generation in real time, and is timely feedbacked to controller 15,
And then facilitate and controlled.
Further, each stent includes stabilizer blade 28, the strut 27 on stabilizer blade 28 and the company on strut 27
Fitting 26, support shaft 23 are mounted on connector 26.In other embodiments, bearing 24 can also be directly installed on connector
On 26.
The superconducting intense magnetic field device for oncotherapy of the present embodiment will be in use, will first intersect annular field generating unit
It is slided along sliding rail 22, carries out the targeting positioning of human body specific position, then control field generating unit and rack by controller 15
25 rotate together, and therapeutic bed is fixed.
The other structures of the superconducting intense magnetic field device for oncotherapy of the present embodiment are used for tumour with embodiment one
The other structures of the superconducting intense magnetic field device for the treatment of are identical, and details are not described herein.
Embodiment three：
Referring to Fig. 3, the superconducting intense magnetic field device for oncotherapy of the present embodiment and embodiment one are used for tumour
The superconducting intense magnetic field device for the treatment of is distinguished as：
Field generating unit includes two superconducting coils 1, and each superconducting coil 1 is oval, and two superconducting coils 1 are V-shaped
It is arranged in a crossed manner.Two superconducting coils 1 of the structure can generate focusing magnetic field, and magnetic field is focused on to the spy of patient in therapeutic bed
Positioning is put, and then drug is guided to be trapped, and constrain the range of drug to the targeting of specific tumors position range.Two superconductions of the structure
Coil 1 is V-shaped arranged in a crossed manner, and the crosspoint of two superconducting coils 1 is in the bottom of two superconducting coils 1, and in the intersection shape
Into compared with high-intensity magnetic field area, magnetic field aggregation is formed.
Further, the major diameter ranging from 60-80cm of each oval superconducting coil 1, short axle are directly 40-60cm,
So that superconducting coil 1 is closer to human body, the magnetic field intensity for focusing on human body specific position is improved.
Further, in other embodiment, each superconducting coil 1 can also be rounded, 60-80cm of each superconducting coil 1.
Further, rack is two plate bodys 41, and two superconducting coils 1 are separately positioned in two plate bodys 41, to pass through
Plate body 41 supports and protects two superconducting coils 1.The V-shaped both sides for being arranged on therapeutic bed of two plate bodys 41, so as to by magnetic field
Two superconducting coil 1V shapes setting of generating unit.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, therapeutic bed includes the bedstead 43 of support bed body 4, and bed body 4 is slidably mounted on bedstead 43, so that bed body 4 can be in bed
It is moved forward and backward on frame 43.
Further, sliding rail 42 is also equipped on bedstead 43, it can the preferably front and rear shifting on bedstead 43 through just bed body 4
It is dynamic.Further, transmission mechanism (not shown) and actuating unit (not shown) on bedstead 43 are installed, driven by actuating unit
Transmission mechanism drives bed body 4 to be moved forward and backward on bedstead 43, and then realizes that bed body 4 is moved relative to field generating unit.Transmission
Mechanism is to conduct the rotating torque of power section and semaphore request is controlled to convert by controller 15, so that bedstead 43 can be with
It carries out three-dimensional mobile.Specifically, transmission mechanism can use the power such as worm gear mechanism, gear mechanism, pneumatic mechanism to transmit
The mechanism of element and guide assembly composition；Power section is that the magnetic screen far from therapeutic bed and field generating unit can control speed governing
Motor, effect are the control requirements by controller 15 to driveline output torque power.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, sensor 5 is mounted on one end of bed body 4, to monitor the magnetic field intensity of field generating unit generation in real time, and in time
Controller 15 is fed back to, and then facilitates and is controlled.
The other structures of the superconducting intense magnetic field device for oncotherapy of the present embodiment are used for tumour with embodiment one
The other structures of the superconducting intense magnetic field device for the treatment of are identical, and details are not described herein.
Example IV：
Referring to Fig. 4, the superconducting intense magnetic field device for oncotherapy of the present embodiment and embodiment one are used for tumour
The superconducting intense magnetic field device for the treatment of is distinguished as：
Field generating unit includes being relatively arranged on above therapeutic bed and two superconducting coils 53 of lower section, each superconducting coil
53 be in evolvent type spiral form.The structure can generate spiral magnetic field, and central magnetic field intensity is high, fringe magnetic field intensity
It is low.Specifically, each 53 ecto-entad of superconducting coil presses form concentric spirals coiling, maximum outside diameter ranging from 60-80cm, two superconductions
Coil 53 pass to the same direction, same intensity electric current, at center realize magnetic field aggregation.In other embodiments, each superconduction
The maximum outside diameter of coil 53 ranging from 40-50cm, minimum diameter ranging from 1-5cm.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, rack includes the stent 52 of two superconducting coils 53 of support, the upper beam 61 of support therapeutic bed overhead support 52, support
The bottom end rail 58 of therapeutic bed underlying holder 52, the upright bar 51 for being vertically arranged in therapeutic bed both ends respectively and each upright bar 51 is supported respectively
Track 54, two tracks 54 along therapeutic bed width direction set, the lower end of each upright bar 51 is slidably mounted on corresponding track 54
On, and the both ends of upper beam 61 are mounted in the upright bar 51 at therapeutic bed both ends, the both ends of bottom end rail 58 are mounted on therapeutic bed both ends
Upright bar 51 on, and therapeutic bed overhead support 52 is slidably mounted on upper beam 61, and therapeutic bed underlying holder 52 is slidably mounted on
On bottom end rail 58, so that each stent 52 can be moved forward and backward along therapeutic bed, and then field generating unit is driven along before and after therapeutic bed
It is mobile；Upright bar simultaneously is moved in orbit, and field generating unit therapeutic bed width direction can be driven to move.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, sliding rail 54 is separately installed on upper beam 51 and bottom end rail 58, is moved with better guide support 52.
Further, the both ends of upper beam 51 are mounted on by the first sliding block 62 in corresponding upright bar 51 respectively, and lower horizontal stroke
The both ends of beam 58 are mounted on by the second sliding block 59 in corresponding upright bar 51 respectively, so as to adjust upper beam 51 and bottom end rail
58 arrive the distance of therapeutic bed, and then adjust the distance that two stents 52 arrive therapeutic bed, to adjust field generating unit to human body
Distance.
Further, the lower end of each upright bar 51 is equipped with third sliding block 56, and each third sliding block 56 is slidably mounted on accordingly
On track 54.More stably to support correspondingly upright bar 51, while slided on track 54 convenient for upright bar 51.Further, respectively
Sliding slot 55 is offered on track 54, so as to accommodating correspondingly third sliding block 56.Further, the lower end of each upright bar 51 is by turning
Axis 57 is mounted on third sliding block 56, just can be moved for greater flexibility with upright bar 51.
Further, therapeutic bed includes bed body 4 and foot lever, is supported bed body 4 on the ground by foot lever.And two stents
52 are separately positioned on the top and lower section of bed body 4.
Further, a kind of specific reality as the superconducting intense magnetic field device provided by the utility model for oncotherapy
Mode is applied, each superconducting coil 53 is in solenoidal structure, and each superconducting coil 53 is provided centrally with magnetic core, and each magnetic core stretches out corresponding superconduction
For coil 53 to form probe, the periphery that strengthened magnetic field accumulation regions and two probes are formed between two probes forms gradient
Field regions.The structure can enhance the magnetic field intensity of field generating unit generation, while can also preferably guide magnetic field.
Further, the diameter range of each solenoidal structure superconducting coil 53 is 3-8cm, passes to the same direction and the electricity of intensity
Stream, to process and to control.Further, the ranging from 1-2cm for stretching out solenoidal structure superconducting coil 53 of magnetic core, with from it is inner to
Outer to form probe, then two probes are oppositely arranged, and respectively pop one's head in and fixed along its axis direction.Further, between two probes
Apart from adjustable, to be easily monitored.Further, each probe is coniform in needle-shaped or platform.
In other embodiments, field generating unit includes two double helix superconducting coils 53, and each superconducting coil 53 is
Eccentric screw coil, and the bottom connection of two superconducting coils 53, and the eccentric position of two superconducting coils 53 is close to being in contact
Bottom, make all spirals there are one points to overlap, and coincidence point is located at the contact point of two superconducting coils 53.Further,
The maximum outside diameter of each superconducting coil 53 ranging from 20-30cm, minimum diameter ranging from 1-5cm, two 53 sides of passing to of superconducting coil
The electric current identical to opposite, intensity；And two groups of superconducting coils 53 are arranged on the top of therapeutic bed and position pair is answered in lower section
It puts, current system is identical in two groups of eccentric screw coils.
The other structures of the superconducting intense magnetic field device for oncotherapy of the present embodiment are used for tumour with embodiment one
The other structures of the superconducting intense magnetic field device for the treatment of are identical, and details are not described herein.
Embodiment five：
Referring to Fig. 5, the superconducting intense magnetic field device for oncotherapy of the present embodiment and embodiment three are used for tumour
The superconducting intense magnetic field device for the treatment of is distinguished as：
In the present embodiment, field generating unit includes two superconducting coils 72, each 72 coiling of superconducting coil coning spiral shell
Coil.And two superconducting coils 72 are oppositely arranged on the both sides of therapeutic bed, meanwhile, each superconducting coil 72 is close to the one of therapeutic bed
The top for cone is held, the other end is bottom end, and the bottom end of each superconducting coil 72 is mounted in rack.Two cones
Superconducting coil 72 is opposite to be put, and centre position exposes magnetic region for human body.The magnetic field and magnetic field that field generating unit generates occur single
First position is controlled by controller 15.
Further, rack includes supporting the platform 71 of each 72 bottom end of superconducting coil and supports the support plate of the platform 71
(figure is not marked), support plate is mounted in therapeutic bed.
The other structures of the superconducting intense magnetic field device for oncotherapy of the present embodiment are used for tumour with embodiment three
The other structures of the superconducting intense magnetic field device for the treatment of are identical, and details are not described herein.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
All any modification, equivalent and improvement made within the spirit and principle of utility model etc., should be included in the utility model
Protection domain within.
Claims (10)
1. for the superconducting intense magnetic field device of oncotherapy, it is characterised in that：Including being used to support the therapeutic bed of human body, for court
Intensity controlled and direction high-intensity magnetic field is generated on the human body of the therapeutic bed to realize the field generating unit of target administration, use
In the controller and the support field generating unit that control the field generating unit and drive the field generating unit phase
For the therapeutic bed movement to adjust the rack in the high-intensity magnetic field direction, the field generating unit and the controller are electrical
It is connected.
2. it to be used for the superconducting intense magnetic field device of oncotherapy as described in claim 1, it is characterised in that：The magnetic field occurs single
Member is made of the combination of superconducting coil, superconducting coil and permanent magnet or the combination of superconducting coil and electromagnetic coil.
3. it to be used for the superconducting intense magnetic field device of oncotherapy as claimed in claim 2, it is characterised in that：The superconducting coil is
Two, and two superconducting coil settings are in X-shaped, V-arrangement, cross or axially opposed shape.
4. it to be used for the superconducting intense magnetic field device of oncotherapy as claimed in claim 2, it is characterised in that：The superconducting coil
Shape is aciculiform, frustro-pyramidal, cylinder, square column type, annular, Crossed Circle, helical annular, double helix is annular, side is annular, both sides
The combination of any one or a few shape in annular, square helical annular, both sides' helical annular.
5. it to be used for the superconducting intense magnetic field device of oncotherapy as claimed in claim 2, it is characterised in that：The superconducting coil
Current range is 0-500A, the magnetic induction intensity ranging from 1-50T that the superconducting coil generates.
6. it to be used for the superconducting intense magnetic field device of oncotherapy as described in claim 1, it is characterised in that：The magnetic field occurs single
Member include two for coordinate generate gradient magnetic round or oval superconducting coils, each superconducting coil it is horizontally-supported
In in the rack, and the horizontal axis of two superconducting coils forms constant setting between two superconducting coils
Magnetic field, the outside of each superconducting coil form the gradient magnetic of intensity diminuendo.
7. it to be used for the superconducting intense magnetic field device of oncotherapy as described in claim 1, it is characterised in that：The magnetic field occurs single
Member includes two circles or oval superconducting coil for generating focusing magnetic field, and two superconducting coils intersect in X shapes or V
Type is arranged in a crossed manner.
8. it to be used for the superconducting intense magnetic field device of oncotherapy as described in claim 1, it is characterised in that：The magnetic field occurs single
Member includes being relatively arranged on two superconducting coils of lower section above the therapeutic bed, and each superconducting coil is in evolvent type spiral shell
It is linear.
9. it to be used for the superconducting intense magnetic field device of oncotherapy as claimed in claim 8, it is characterised in that：Each superconducting coil
In solenoidal structure, each superconducting coil is provided centrally with magnetic core, and each magnetic core stretches out the corresponding superconducting coil with shape
Into probe, the periphery that strengthened magnetic field accumulation regions and two probes are formed between two probes forms gradient magnetic
Place.
10. it to be used for the superconducting intense magnetic field device of oncotherapy as described in claim 1, it is characterised in that：It further includes to supervise
The sensor of magnetic induction intensity is surveyed, the sensor is electrical connected with the controller, and the sensor is installed on the treatment
On bed.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107174742A (en) * | 2017-05-02 | 2017-09-19 | 深圳磁实科技有限公司 | Superconducting intense magnetic field device for oncotherapy |
| CN109045475A (en) * | 2018-09-11 | 2018-12-21 | 同济大学 | The method of oscillating magnetic field device and killing tumor cell for killing tumor cell |
| CN111250016A (en) * | 2020-02-06 | 2020-06-09 | 徐国栋 | Liquid plasma device for treating tumor and skin disease |
| CN113825982A (en) * | 2019-05-15 | 2021-12-21 | 蒂森克虏伯普利斯坦股份公司 | Rotor position sensor and motor vehicle steering system with a rotor position sensor |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107174742A (en) * | 2017-05-02 | 2017-09-19 | 深圳磁实科技有限公司 | Superconducting intense magnetic field device for oncotherapy |
| CN107174742B (en) * | 2017-05-02 | 2024-05-07 | 商澎 | Superconducting strong magnetic field device for tumor treatment |
| CN109045475A (en) * | 2018-09-11 | 2018-12-21 | 同济大学 | The method of oscillating magnetic field device and killing tumor cell for killing tumor cell |
| CN109045475B (en) * | 2018-09-11 | 2021-11-02 | 同济大学 | Vibrating magnetic field device for killing tumor cells |
| CN113825982A (en) * | 2019-05-15 | 2021-12-21 | 蒂森克虏伯普利斯坦股份公司 | Rotor position sensor and motor vehicle steering system with a rotor position sensor |
| CN113825982B (en) * | 2019-05-15 | 2024-01-09 | 蒂森克虏伯普利斯坦股份公司 | Rotor position sensor and motor vehicle steering system having a rotor position sensor |
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