CN207237438U - Bio-pharmaceuticals isolates and purifies filtration apparatus - Google Patents

Abstract

The utility model relates to a biopharmaceutical separation and purification filter device, which belongs to the technical field of biopharmaceutical devices, and comprises a box body, the top of the box body is provided with a feed port, the bottom of the box body is provided with a discharge port, and the box body is provided with a first filter plate and the second filter plate, the top of the first filter plate and the second filter plate are provided with an air delivery pipe, the two ends of the air delivery pipe are fixed on the side wall of the box, the bottom of the air delivery pipe is provided with a downward spray nozzle, the air delivery pipe The upper part is connected with an air inlet pipe, on which an airflow stirring device is installed rotatingly, and the other end of the air inlet pipe extends out of the box to connect with an air pump, and the air inlet end of the air pump is connected with an inert gas source bottle through a pipeline. The utility model is provided with a double-layer filter plate, and then combined with an air flow stirring device above the filter plate, so that the filter effect is better, and the filter plate is cleaned by the air jet head to prevent the filter plate from being blocked, thereby increasing the filtration efficiency.

Description

Biopharmaceutical separation and purification filtration device

technical field

The utility model belongs to the technical field of biopharmaceutical devices, in particular to a separation, purification and filtration device for biopharmaceuticals.

Background technique

There is an important step in the process of biopharmaceuticals, that is, separation and purification. The so-called separation and purification is to separate specific proteins, nucleic acids, sugars, lipids and other substances in biological raw materials through technical means such as filtration.

There are various types of separation and purification equipment in the prior art, and the traditional filtering device has been used for a long time, and the filter screen is easily blocked, which reduces the filtration efficiency and the filtration effect.

Utility model content

The purpose of the utility model is to provide a biopharmaceutical separation and purification filter device, which solves the problem that the filter screen is easily blocked after a long time in the existing device, so that the filter efficiency is reduced and the filter effect is reduced.

The utility model biopharmaceutical separation and purification filtering device comprises a box, the top of the box is provided with a feed port, the bottom of the box is provided with a discharge port, the box is provided with a first filter plate and a second filter plate, the first filter plate Both the first filter plate and the second filter plate are composed of filter membranes capable of filtering biological raw materials. Air pipes are arranged above the first filter plate and the second filter plate, and the two ends of the air pipe are fixed on the side wall of the box. There is an air jet nozzle facing downwards, an air intake pipe is connected above the air delivery pipe, and an airflow stirring device is installed on the air intake pipe, and the other end of the air intake pipe extends out of the box to connect with an air pump. The power plug of the air pump is connected to the indoor power supply, and the air pump’s The gas inlet end is connected to an inert gas source bottle through a pipeline, and a valve is arranged on the pipeline.

The air flow stirring device includes a hollow disc, which is rotatably sleeved on the air intake pipe, and the air intake pipe is provided with a vent hole connected to the hollow disc, and no less than two hollow discs are connected to the outer side of the hollow disc. An air guide tube in a circular array at the center of the circle, the air guide tube is designed in a circular arc shape, and the outside of the air guide tube is connected with a restrictor tube, and the restrictor tube is designed in a funnel shape.

Both the top and the bottom of the hollow disc are provided with grooves, bearings are fixed in the grooves, the inner ring of the bearing is fixed to the intake pipe, and the outer ring of the bearing is fixed in the groove.

An air outlet one and an air outlet two are respectively arranged on the box body side wall below the top wall of the box and below the first filter plate, and the first air outlet and the second air outlet are connected to an exhaust fan through a pipeline, and the power switch of the exhaust fan is connected to the exhaust fan. The indoor power supply and the air outlet of the exhaust fan are connected to the connecting pipeline between the air pump and the inert gas source bottle through pipelines. The inert gas can be recovered and reused to prevent waste.

A feed pipe is provided at the feed inlet, a feed hopper is provided at the top of the feed pipe, a valve is provided on the feed pipe, a discharge pipe is provided at the discharge port, and a discharge valve is provided on the discharge pipe. Prevent inert gas from escaping when feeding.

The bottom of the box body is funnel-shaped, and the discharge port is at the lowest point of the funnel-shaped bottom. Easy to discharge.

Working principle: When in use, the material enters from the feeding hopper and flows to the first filter plate. The air flow stirring device stirs the material to prevent the debris from settling to the bottom and affecting the filtration, and the first filter plate is filtered through the air jet head. Blow air to clean up the sundries in the first filter plate to prevent clogging caused by a long time and affect the filtration efficiency. The liquid filtered for the first time flows to the second filter plate for another filter to make the filtering effect better, and the inert gas It is recovered by exhaust fan and then recycled to prevent waste.

Compared with the prior art, the utility model has the advantages of:

By providing double-layer filter plates and then combining with the air flow stirring device above the filter plates, the filtering effect is better, and the filter plates are cleaned by the air jet head to prevent the filter plates from being blocked, thereby increasing the filtration efficiency.

Description of drawings

Fig. 1 is the structural representation of the utility model;

Fig. 2 is the schematic diagram of the enlarged structure of place A in Fig. 1;

Fig. 3 is the structural representation of airflow stirring device;

In the figure: 1. Box body, 2. Feed hopper, 3. Feed pipe, 4. Air intake pipe, 5. Hollow disk, 6. Air guide pipe, 7. Flow limiting pipe, 8. Air delivery pipe, 9. Air jet Head, 10, first filter plate, 11, second filter plate, 12, bearing, 13, discharge pipe, 14, discharge valve, 15, inert gas source bottle, 16, exhaust fan, 17, air pump, 18 , air outlet two, 19, air outlet one, 20, air vent.

Detailed ways

The specific embodiment of the utility model will be described in further detail below with reference to the accompanying drawings.

The biopharmaceutical separation and purification filtration device as shown in Figures 1 to 3 includes a box body 1, the top of the box body 1 is provided with a feed port, the bottom of the box body 1 is provided with a discharge port, and the box body 1 is provided with a first filter. Plate 10 and the second filter plate 11, the top of the first filter plate 10 and the second filter plate 11 are all provided with a gas delivery pipe 8, the bottom of the gas delivery pipe 8 is provided with a spray nozzle 9 spraying downwards, and the top of the gas delivery pipe 8 is connected with Intake pipe 4, airflow stirring device is installed on the air inlet pipe 4 rotation, the other end of air inlet pipe 4 stretches out casing 1 and is connected with air pump 17, and the air inlet end of air pump 17 is connected with inert gas source bottle 15.

The air flow stirring device includes a hollow disc 5, the hollow disc 5 is rotatably sleeved on the air intake pipe 4, the air intake pipe 4 is provided with a ventilation hole 20 communicating with the hollow disc 5, and the outside of the hollow disc 5 is connected with many The two air guide tubes 6 are circularly arrayed about the hollow disc 5, the air guide tubes 6 are designed in a circular arc shape, and the outside of the air guide tubes 6 is connected with a restrictor tube 7, and the restrictor tube 7 is designed in a funnel shape.

The top and the bottom of the hollow disc 5 are provided with grooves, and bearings 12 are fixed in the grooves, the inner ring of the bearing 12 is fixed with the intake pipe 4, and the outer ring of the bearing 12 is fixed in the grooves.

An air outlet one 19 and an air outlet two 18 are respectively arranged on the side wall of the box body 1 below the top wall of the box body 1 and below the first filter plate 10, and the first air outlet 19 and the second air outlet 18 are connected with an exhaust fan through a pipeline 16. The air outlet of the suction fan 16 is connected to the connecting pipe between the air pump 17 and the inert gas source bottle 15 through a pipe.

A feed pipe 3 is provided at the feed inlet, a feed hopper 2 is provided at the top of the feed pipe 3, a valve is provided on the feed pipe 3, a discharge pipe 13 is provided at the discharge port, and a discharge pipe 13 is arranged on the discharge pipe 13. A discharge valve 14 is provided.

The bottom of the box body 1 is funnel-shaped, and the discharge port is at the lowest point of the funnel-shaped bottom.

To sum up, the utility model is provided with a double-layer filter plate, and then combined with the air flow stirring device above the filter plate, so that the filtering effect is better, and the filter plate is cleaned by the air jet head to prevent the filter plate from being blocked, so that the filter plate Increased efficiency.

Claims (6)

1. A separation, purification and filtration device for biopharmaceuticals, comprising a casing (1), the top of the casing (1) is provided with a feed inlet, the bottom of the casing (1) is provided with a discharge outlet, and the casing (1) is provided with a The first filter plate (10) and the second filter plate (11), are characterized in that: the top of the first filter plate (10) and the second filter plate (11) are all provided with an air delivery pipe (8), and the air delivery pipe (8) ) bottom is provided with an air nozzle (9) for spraying downwards, an air intake pipe (4) is connected to the top of the air delivery pipe (8), and an airflow stirring device is installed on the air intake pipe (4), and the other end of the air intake pipe (4) extends Out of the casing (1) is connected with an air pump (17), and the inlet end of the air pump (17) is connected with an inert gas source bottle (15). 2. The biopharmaceutical separation, purification and filtration device according to claim 1, characterized in that: the air flow agitation device comprises a hollow disc (5), and the hollow disc (5) is rotatably sleeved on the air inlet pipe (4) for further The trachea (4) is provided with a ventilation hole (20) connected to the hollow disc (5), and the outer side of the hollow disc (5) is connected with no less than two air ducts about the circular array of the hollow disc (5). (6), the air guide tube (6) is designed in a circular arc shape, and the outside of the air guide tube (6) is connected with a restrictor tube (7), and the restrictor tube (7) is designed in a funnel shape. 3. The biopharmaceutical separation, purification and filtration device according to claim 2, characterized in that: the top and bottom of the hollow disc (5) are provided with grooves, and bearings (12) are fixed in the grooves, and the bearings (12 ) inner ring is fixed with the intake pipe (4), and the outer ring of the bearing (12) is fixed in the groove. 4. The separation, purification and filtration device for biopharmaceuticals according to claim 3, characterized in that: the side walls of the casing (1) below the top wall of the casing (1) and below the first filter plate (10) are respectively arranged Air outlet one (19) and air outlet two (18) are arranged, and air outlet one (19) and air outlet two (18) are connected with exhaust fan (16) by pipeline, and the air outlet of exhaust fan (16) is connected by pipeline On the connecting pipeline between the air pump (17) and the inert gas source bottle (15). 5. The biopharmaceutical separation, purification and filtration device according to claim 1, characterized in that: a feed pipe (3) is provided at the feed inlet, and a feed hopper (2) is provided at the top of the feed pipe (3) , the feed pipe (3) is provided with a valve, the discharge port is provided with a discharge pipe (13), and the discharge pipe (13) is provided with a discharge valve (14). 6. The biopharmaceutical separation, purification and filtration device according to claim 1, characterized in that: the bottom of the box (1) is funnel-shaped, and the outlet is at the lowest point of the funnel-shaped bottom.