CN206549218U - A kind of biological medicine production filtering extraction element - Google Patents
A kind of biological medicine production filtering extraction element Download PDFInfo
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- CN206549218U CN206549218U CN201720137756.XU CN201720137756U CN206549218U CN 206549218 U CN206549218 U CN 206549218U CN 201720137756 U CN201720137756 U CN 201720137756U CN 206549218 U CN206549218 U CN 206549218U
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- 238000001914 filtration Methods 0.000 title claims abstract description 27
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 12
- 238000000605 extraction Methods 0.000 title claims description 12
- 239000003814 drug Substances 0.000 title abstract description 14
- 239000012528 membrane Substances 0.000 claims abstract description 44
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 26
- 238000001471 micro-filtration Methods 0.000 claims abstract description 17
- 238000005192 partition Methods 0.000 claims abstract description 11
- 238000000265 homogenisation Methods 0.000 claims abstract description 9
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000000523 sample Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000011148 porous material Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 4
- 239000002033 PVDF binder Substances 0.000 claims description 3
- 229920000515 polycarbonate Polymers 0.000 claims description 3
- 239000004417 polycarbonate Substances 0.000 claims description 3
- 229920002981 polyvinylidene fluoride Polymers 0.000 claims description 3
- 210000003437 trachea Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 abstract description 10
- 239000012535 impurity Substances 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000005374 membrane filtration Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000012237 artificial material Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
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Abstract
本实用新型公开了一种生物医药生产用过滤提取装置,包括壳体,所述壳体内部从上往下分别设置有均质仓、过滤仓和底仓,所述隔板下方的凸起与壳体底部之间固定安装有微滤膜和超滤膜,所述隔板左侧设置的下料管内固定安装有球阀,所述壳体顶部从左至右分别设置有进料管、超声波发生器和进水管,所述均质仓顶部固定安装的探头穿过壳体与超声波发生器连接,所述壳体左侧设置的空气增压器与过滤仓通过气管连接,所述底仓内固定安装有加热管,所述壳体右侧固定安装有蒸汽管和出料管,所述超滤膜由板框和板框内部均匀排列的超滤膜丝构成。本实用新型采用双重过滤,对药液中的杂质进行分层过滤,实现快速过滤,有效的提高工作效率。
The utility model discloses a filtering and extracting device for biomedicine production, which comprises a housing, and the inside of the housing is respectively provided with a homogeneous chamber, a filtering chamber and a bottom chamber from top to bottom, and the protrusions below the partition are connected with the bottom chamber. A microfiltration membrane and an ultrafiltration membrane are fixedly installed between the bottom of the housing, and a ball valve is fixedly installed in the feeding pipe on the left side of the partition, and a feeding pipe, an ultrasonic generator, and an ultrasonic generator are respectively installed on the top of the housing from left to right. The probe fixed on the top of the homogenization chamber is connected to the ultrasonic generator through the casing, the air booster on the left side of the casing is connected to the filter chamber through the air pipe, and the bottom chamber is fixed A heating pipe is installed, a steam pipe and a discharge pipe are fixedly installed on the right side of the housing, and the ultrafiltration membrane is composed of a plate frame and ultrafiltration membrane wires uniformly arranged inside the plate frame. The utility model adopts double filtration to carry out layered filtration on the impurities in the liquid medicine, realizes rapid filtration, and effectively improves work efficiency.
Description
技术领域technical field
本实用新型涉及制药设备技术领域,具体为一种生物医药生产用过滤提取装置。The utility model relates to the technical field of pharmaceutical equipment, in particular to a filtration extraction device for biomedicine production.
背景技术Background technique
目前,随着我国的快速发展,医疗制药设备汲取着国际顶尖技术得到长足的提高与进步,而在制药过程中对药物进行过滤提纯更是重要的一环,同时生物医学是从分子、细胞、组织、器官乃至整个人体系统多层次认识人体的结构、功能和其他生命现象,从而研究用于防病、治病、人体功能辅助及卫生保健的人工材料、制品、装置和系统技术,如何将两者结合形成一种适用于生物医学药品的过滤提纯装置的问题是需要去解决的。At present, with the rapid development of our country, medical and pharmaceutical equipment has been greatly improved and progressed by absorbing the international top technology, and the filtration and purification of drugs in the pharmaceutical process is an important part. At the same time, biomedicine is from molecules, cells, Tissues, organs and even the whole human body system have a multi-level understanding of the structure, function and other life phenomena of the human body, so as to study the artificial materials, products, devices and system technologies used for disease prevention, treatment, human body function assistance and health care, how to combine the two The combination of the former and the formation of a filter purification device suitable for biomedical drugs needs to be solved.
发明内容Contents of the invention
本实用新型的目的在于提供一种生物医药生产用过滤提取装置,以解决上述背景技术中提出的问题,所具有的有益效果是:具有对药液中的杂质进行分层过滤,实现快速过滤,有效的提高工作效率,过滤效果好,适用于生物医学制药。The purpose of the utility model is to provide a filter extraction device for biomedicine production to solve the problems raised in the above-mentioned background technology. Effectively improve work efficiency, good filtering effect, suitable for biomedical pharmaceuticals.
为实现上述目的,本实用新型提供如下技术方案:一种生物医药生产用过滤提取装置,包括壳体,所述壳体内部从上往下分别设置有均质仓、过滤仓和底仓,且均质仓和过滤仓之间设置有隔板,所述隔板下方的凸起与壳体底部之间固定安装有微滤膜和超滤膜,且微滤膜和超滤膜左右排列将过滤仓分为三层,所述隔板左侧设置的下料管内固定安装有球阀,所述壳体顶部从左至右分别设置有进料管、超声波发生器和进水管,且进料管和进水管均穿过壳体与均质仓连接,所述均质仓顶部固定安装的探头穿过壳体与超声波发生器连接,所述壳体左侧设置的空气增压器与过滤仓通过气管连接,所述空气增压器通过气管与左侧的空气净化器连接,所述底仓内固定安装有加热管,所述壳体右侧固定安装有蒸汽管和出料管,且蒸汽管和出料管均穿过壳体与过滤仓连接,所述超滤膜由板框和板框内部均匀排列的超滤膜丝构成。In order to achieve the above purpose, the utility model provides the following technical solutions: a filtration and extraction device for biomedicine production, including a housing, and the inside of the housing is respectively provided with a homogeneous chamber, a filter chamber and a bottom chamber from top to bottom, and There is a partition between the homogeneous chamber and the filter chamber, and a microfiltration membrane and an ultrafiltration membrane are fixedly installed between the protrusion below the partition and the bottom of the housing, and the microfiltration membrane and the ultrafiltration membrane are arranged left and right to filter The warehouse is divided into three layers, and a ball valve is fixedly installed in the feeding pipe on the left side of the partition, and a feeding pipe, an ultrasonic generator and a water inlet pipe are respectively arranged on the top of the housing from left to right, and the feeding pipe and The water inlet pipes pass through the housing to connect with the homogenization chamber, and the fixed probe on the top of the homogenization chamber passes through the housing to connect with the ultrasonic generator. The air booster is connected to the air cleaner on the left side through the air pipe, the heating pipe is fixedly installed in the bottom compartment, the steam pipe and the discharge pipe are fixedly installed on the right side of the housing, and the steam pipe and The discharge pipes pass through the housing and are connected to the filter chamber, and the ultrafiltration membrane is composed of a plate frame and ultrafiltration membrane wires arranged uniformly inside the plate frame.
优选的,所述过滤仓底部左侧固定安装有温度传感器。Preferably, a temperature sensor is fixedly installed on the left side of the bottom of the filter chamber.
优选的,所述蒸汽管设置在出料管的上方。Preferably, the steam pipe is arranged above the discharge pipe.
优选的,所述壳体左侧设置有压力表,且压力表通过气管穿过壳体与过滤仓连接。Preferably, a pressure gauge is provided on the left side of the casing, and the pressure gauge passes through the casing through an air pipe and is connected to the filter chamber.
优选的,所述微滤膜主要由聚偏氟乙烯材料制成,且微滤膜孔径为0.02~10μm。Preferably, the microfiltration membrane is mainly made of polyvinylidene fluoride, and the pore size of the microfiltration membrane is 0.02-10 μm.
优选的,所述超滤膜主要由聚碳酸酯材料制成,且超滤膜孔径为0.001~0.02μm。Preferably, the ultrafiltration membrane is mainly made of polycarbonate material, and the pore size of the ultrafiltration membrane is 0.001-0.02 μm.
与现有技术相比,本实用新型的有益效果是:该设备采用双重过滤,对药液中的杂质进行分层过滤,实现快速过滤,有效的提高工作效率,并配备超声波发生器,对药液进行均质处理,使药物充分混合,且空气增压器的设置,能对设备进行加压处理,使药物中的杂质在压力作用下不断的经过微滤膜和超滤膜过滤,从而获得提纯药液,操作人员可以通过压力表观察设备内的压力,从而合理的对设备内的压强进行合理的控制,同时设备内设置有温度传感器和加热管,可以对药液进行加热并监测温度,提高分子间的流速,从而提高过滤速度,本设备能够多级过滤,过滤速度快,并采用微滤膜和超滤膜,过滤效果好,适用于生物医学制药。Compared with the prior art, the beneficial effects of the utility model are: the equipment adopts double filtration, performs layered filtration on the impurities in the liquid medicine, realizes rapid filtration, effectively improves work efficiency, and is equipped with an ultrasonic generator, The liquid is homogenized to make the medicine fully mixed, and the setting of the air booster can pressurize the equipment, so that the impurities in the medicine are continuously filtered through the microfiltration membrane and ultrafiltration membrane under pressure, so as to obtain To purify the liquid medicine, the operator can observe the pressure in the equipment through the pressure gauge, so as to reasonably control the pressure in the equipment. At the same time, the equipment is equipped with a temperature sensor and a heating tube, which can heat the liquid medicine and monitor the temperature. Increase the flow rate between molecules, thereby increasing the filtration speed. This equipment can filter in multiple stages, with fast filtration speed, and adopts microfiltration membrane and ultrafiltration membrane, which has good filtration effect and is suitable for biomedical pharmaceuticals.
附图说明Description of drawings
图1为本实用新型的结构示意图;Fig. 1 is the structural representation of the utility model;
图2为本实用新型超滤膜的结构示意图。Fig. 2 is a structural schematic diagram of the ultrafiltration membrane of the present invention.
图中:1-壳体;2-进料管;3-超声波发生器;4-探头;5-进水管;6-下料管;7-球阀;8-压力表;9-气管;10-空气增压器;11-空气净化器;12-温度传感器;13-微滤膜;14-加热管;15-超滤膜;16-底仓;17-均质仓;18-隔板;19-蒸汽管;20-过滤仓;21-出料管;22-板框;23-超滤膜丝。In the figure: 1-shell; 2-feeding pipe; 3-ultrasonic generator; 4-probe; 5-inlet pipe; 6-feeding pipe; 7-ball valve; 8-pressure gauge; Air booster; 11-air purifier; 12-temperature sensor; 13-microfiltration membrane; 14-heating tube; 15-ultrafiltration membrane; - steam pipe; 20 - filter chamber; 21 - discharge pipe; 22 - plate frame; 23 - ultrafiltration membrane wire.
具体实施方式detailed description
下面将结合本实用新型实施例中的附图,对本实用新型实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本实用新型一部分实施例,而不是全部的实施例。基于本实用新型中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本实用新型保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. example. Based on the embodiments of the present utility model, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of the present utility model.
请参阅图1和图2,本实用新型提供的一种实施例:一种生物医药生产用过滤提取装置,包括壳体1,壳体1内部从上往下分别设置有均质仓17、过滤仓20和底仓16,且均质仓17和过滤仓20之间设置有隔板18,隔板18下方的凸起与壳体1底部之间固定安装有微滤膜13和超滤膜15,且微滤膜13和超滤膜15左右排列将过滤仓20分为三层,隔板18左侧设置的下料管6内固定安装有球阀7,壳体1顶部从左至右分别设置有进料管2、超声波发生器3和进水管5,且进料管2和进水管5均穿过壳体1与均质仓17连接,均质仓17顶部固定安装的探头4穿过壳体1与超声波发生器3连接,壳体1左侧设置的空气增压器10与过滤仓20通过气管9连接,空气增压器10通过气管9与左侧的空气净化器11连接,底仓16内固定安装有加热管14,壳体1右侧固定安装有蒸汽管19和出料管21,且蒸汽管19和出料管21均穿过壳体1与过滤仓20连接,超滤膜15由板框22和板框22内部均匀排列的超滤膜丝23构成,过滤仓20底部左侧固定安装有温度传感器12,蒸汽管19设置在出料管21的上方,壳体1左侧设置有压力表8,且压力表8通过气管9穿过壳体1与过滤仓20连接,微滤膜13主要由聚偏氟乙烯材料制成,且微滤膜13孔径为0.02~10μm,超滤膜15主要由聚碳酸酯材料制成,且超滤膜15孔径为0.001~0.02μm。Please refer to Fig. 1 and Fig. 2, an embodiment provided by the utility model: a filtration and extraction device for biomedicine production, including a housing 1, the interior of the housing 1 is respectively provided with a homogeneous chamber 17, a filter The bin 20 and the bottom bin 16, and a partition 18 is arranged between the homogeneous bin 17 and the filter bin 20, and a microfiltration membrane 13 and an ultrafiltration membrane 15 are fixedly installed between the protrusion below the partition 18 and the bottom of the housing 1 , and the microfiltration membrane 13 and the ultrafiltration membrane 15 are arranged left and right to divide the filter chamber 20 into three layers, and a ball valve 7 is fixedly installed in the feeding pipe 6 arranged on the left side of the partition 18, and the top of the housing 1 is respectively arranged from left to right There are feed pipe 2, ultrasonic generator 3 and water inlet pipe 5, and both feed pipe 2 and water inlet pipe 5 pass through the shell 1 to connect with the homogenization chamber 17, and the probe 4 fixedly installed on the top of the homogeneity chamber 17 passes through the shell The body 1 is connected to the ultrasonic generator 3, the air booster 10 on the left side of the housing 1 is connected to the filter chamber 20 through the air pipe 9, the air booster 10 is connected to the air cleaner 11 on the left side through the air pipe 9, and the bottom chamber A heating pipe 14 is fixedly installed in 16, a steam pipe 19 and a discharge pipe 21 are fixedly installed on the right side of the housing 1, and the steam pipe 19 and the discharge pipe 21 pass through the housing 1 to connect with the filter chamber 20, and the ultrafiltration membrane 15 is composed of plate frame 22 and ultrafiltration membrane filaments 23 evenly arranged inside the plate frame 22. A temperature sensor 12 is fixedly installed on the left side of the bottom of the filter chamber 20. The steam pipe 19 is arranged above the discharge pipe 21. The left side of the housing 1 A pressure gauge 8 is provided, and the pressure gauge 8 is connected to the filter chamber 20 through the casing 1 through the air pipe 9. The microfiltration membrane 13 is mainly made of polyvinylidene fluoride material, and the microfiltration membrane 13 has a pore size of 0.02-10 μm, ultra- The filter membrane 15 is mainly made of polycarbonate material, and the pore diameter of the ultrafiltration membrane 15 is 0.001-0.02 μm.
工作原理:使用时,将药物从进料管2投入,并从进水管5注入无菌水,随后打开超声波发生器3对均质仓内的混合药液进行均质处理,随后打开球阀7使药液从下料管6进入过滤仓20左侧,同时关闭球阀7打开空气净化器11和空气增压器10对设备内充入无菌空气并增压,从而使混合药液经过微滤膜13和超滤膜15双重过滤,进而从出料管21获得提纯药液,完成对药物的过滤提取,同时可以使用加热管14配合温度传感器12对设备进行加热,并可以对需要蒸馏提纯的药液加热,药液蒸汽可以通过蒸汽管19排出收集,且可以通过压力表8直接观察设备内的压力大小。Working principle: when in use, the drug is put into the feed pipe 2, and the sterile water is injected from the water inlet pipe 5, and then the ultrasonic generator 3 is turned on to homogenize the mixed drug solution in the homogenization chamber, and then the ball valve 7 is opened to make it The medicinal liquid enters the left side of the filter chamber 20 from the feeding pipe 6, and at the same time closes the ball valve 7 and opens the air purifier 11 and the air booster 10 to fill the equipment with sterile air and pressurize, so that the mixed medicinal liquid passes through the microfiltration membrane 13 and ultrafiltration membrane 15 double filtration, and then obtain the purified medicinal liquid from the discharge pipe 21, complete the filtration and extraction of the medicinals, at the same time, the heating tube 14 can be used to cooperate with the temperature sensor 12 to heat the equipment, and the medicinals that need to be distilled and purified can be heated. The liquid is heated, and the liquid medicine vapor can be discharged and collected through the steam pipe 19, and the pressure in the equipment can be directly observed through the pressure gauge 8.
对于本领域技术人员而言,显然本实用新型不限于上述示范性实施例的细节,而且在不背离本实用新型的精神或基本特征的情况下,能够以其他的具体形式实现本实用新型。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本实用新型的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本实用新型内。不应将权利要求中的任何附图标记视为限制所涉及的权利要求。It is obvious to those skilled in the art that the present invention is not limited to the details of the above-mentioned exemplary embodiments, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, no matter from all points of view, the embodiments should be regarded as exemplary and non-restrictive, and the scope of the present invention is defined by the appended claims rather than the above description, so it is intended to fall within the scope of the claims All changes within the meaning and range of equivalents of the required elements are included in the present invention. Any reference sign in a claim should not be construed as limiting the claim concerned.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108837702A (en) * | 2018-06-12 | 2018-11-20 | 合肥丰洁生物科技有限公司 | A kind of separation equipment of high-pressure membrane concentration |
CN114653136A (en) * | 2022-04-21 | 2022-06-24 | 四川科伦药业股份有限公司 | Filtering method and filtering device for fat emulsion injection |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108837702A (en) * | 2018-06-12 | 2018-11-20 | 合肥丰洁生物科技有限公司 | A kind of separation equipment of high-pressure membrane concentration |
CN114653136A (en) * | 2022-04-21 | 2022-06-24 | 四川科伦药业股份有限公司 | Filtering method and filtering device for fat emulsion injection |
CN114653136B (en) * | 2022-04-21 | 2024-08-09 | 四川科伦药业股份有限公司 | Filtering method and filtering device for fat emulsion injection |
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