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CN206408230U - Oscillating uniform device and Ames test instrument - Google Patents

Oscillating uniform device and Ames test instrument Download PDF

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Publication number
CN206408230U
CN206408230U CN201621082978.8U CN201621082978U CN206408230U CN 206408230 U CN206408230 U CN 206408230U CN 201621082978 U CN201621082978 U CN 201621082978U CN 206408230 U CN206408230 U CN 206408230U
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China
Prior art keywords
culture dish
oscillating uniform
uniform device
driving wheel
frame
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CN201621082978.8U
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Chinese (zh)
Inventor
郑劲林
杨富成
李朝文
刘玉杰
赵银龙
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Beijing Huironghe Technology Co Ltd
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Beijing Huironghe Technology Co Ltd
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Priority to CN201621082978.8U priority Critical patent/CN206408230U/en
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Abstract

The utility model provides a kind of oscillating uniform device and Ames test instrument.Oscillating uniform device includes:Base;Driving wheel, is rotatably installed on base;Driven pulley, is rotatably installed on base;And shaking-up frame, driving wheel and driven pulley are rotatably installed on respectively at two position;Base, driving wheel, driven pulley and shaking-up frame collectively form crank and rocker mechanism or parallel-crank mechanism.Because driving wheel, driven pulley, shaking-up frame and base composition parallel-crank mechanism or crank and rocker mechanism, can quickly and evenly be mixed to many kinds of substance in culture dish in oscillating uniform device and Ames test instrument of the present utility model.Further, shaking-up frame is installed on two rollers by substrate, and two rollers are respectively arranged in driving wheel and driven pulley, and the setting of orientation lever, culture dish can be made only to be rocked, fluctuation very little in the vertical direction, it is ensured that the robust motion of oscillating uniform device and excellent to shake up effect.

Description

Oscillating uniform device and Ames test instrument
Technical field
The utility model is related to Ames test technical field, more particularly to a kind of oscillating uniform device and with the oscillating uniform device Ames test instrument.
Background technology
B.N.Ames etc. set up in 1975 through the effort of more than ten years and continues to develop perfect salmonella back mutation examination (also known as Salmonella reversion test, Ames test) is tested widely to be used by countries in the world.The method than faster, it is easy, sensitive, economical, And suitable for test mixing thing, reflect the comprehensive effect of multiple pollutant.Food additives can be detected with Salmonella reversion test, are made up The mutagenicity of product etc., thus speculates its carcinogenicity;With Salmonella reversion test detect Source water and drinking water mutagenicity, explore compared with The relatively sanitary safe disinfectant measure of current methods;Or the mutagenicity of detection municipal sewage and industrial wastewater, with reference to chemistry point Analysis, follows the trail of pollution sources, and foundation is provided for research Preventing Countermeasures;Detect soil, sludge, industrial residue compost, the cause of waste ashes Mutability, after preventing that the soil for maintaining life from being polluted by mutagen, passes through the murrain mankind;Detect gaseous contaminant Mutagenicity, prevent pollutant via air, occur potential hazard to human body by breathing;Compound is studied with Salmonella reversion test The relation of structure and mutagens, theoretical foundation is provided to synthesize to noval chemical compound of the environment without potential hazard;Detect agricultural chemicals micro- Mutagenicity before and after biodegradation, understands agricultural chemicals whether there is hidden danger in metabolic process to the mankind after application;Also useful Ames examinations The anti-mutation-ure of screening is tested, new anticarcinogen etc. is researched and developed.Existing Ames test be all experimenter using dropper to Addition reagent in culture dish, automaticity is low, and cost of labor is high, although ensure that certain experimental precision, but also can be by Cause experimental result deviation huge in the error of people.
Utility model content
The purpose of this utility model aims to provide a kind of oscillating uniform device, and it can will drive culture dish to be rocked, so that Many kinds of substance in culture dish is well mixed, to realize that full automatic Ames test instrument provides support.
Therefore, the utility model provides a kind of oscillating uniform device for Ames test instrument, including:
Base;
Driving wheel, is rotatably installed on the base;
Driven pulley, is rotatably installed on the base;With
Shaking-up frame, the driving wheel and the driven pulley are rotatably installed at two position respectively;
The base, the driving wheel, the driven pulley collectively form crank and rocker mechanism or parallel with the shaking-up frame Quadrangular mechanism, to make the shaking-up frame at least drive training directly or indirectly placed thereon when the driving wheel is rotated Ware motion is supported, so that many kinds of substance in the culture dish is well mixed.
Further, the shaking-up frame includes substrate, and the substrate is rotatable in two positions difference of its lower surface Ground is installed on the driving wheel and the driven pulley.
Further, the substrate offers turn hole at two positions of its lower surface;
The oscillating uniform device also includes two rollers, is respectively arranged in the upper surface of the driving wheel and the driven pulley, And be located at respectively in two turn holes.
Further, the oscillating uniform device also includes lowering or hoisting gear and carrying disk, and the lowering or hoisting gear is installed on described shake Even frame;
The carrying disk is used to place the culture dish, and is installed on the lowering or hoisting gear, with the lowering or hoisting gear Drive lower progress elevating movement.
Further, the shaking-up frame also includes side plate, and its upper end is arranged on a side of the substrate, and described Lowering or hoisting gear is installed on the side plate.
Further, the carrying disk is sucker.
Further, the oscillating uniform device also includes:Position detecting device, is configured to detect whether the shaking-up frame is in Or return to initial position.
Further, the position detecting device includes being installed on the signal patch of the edge of the substrate and is installed on institute State the sensor on base.
Further, the base, the driving wheel, the driven pulley and the shaking-up frame collectively form parallelogram Mechanism;And the oscillating uniform device also includes:
First orientation lever, it is fixed on the substrate, and parallel to the direction that the driven pulley is pointed to by the driving wheel;
Second orientation lever, is vertically arranged with first orientation lever, and its one end is slidably mounted on described first and determined To bar, the other end is slidably mounted on the base.
The utility model additionally provides a kind of Ames test instrument, and it includes any of the above-described kind of oscillating uniform device, described to shake up Device is configured to add after mixed liquor in the ware disk of culture dish, drives the ware disk motion, so that mixed in the ware disk Liquid is closed to be well mixed.
Because driving wheel, driven pulley, shaking-up frame and base group in oscillating uniform device and Ames test instrument of the present utility model Into parallel-crank mechanism or crank and rocker mechanism, many kinds of substance in culture dish can quickly and evenly be mixed.Enter one Step ground, shaking-up frame is installed on two rollers by substrate, and two rollers are respectively arranged in driving wheel and driven pulley, and orientation The setting of bar, can be such that culture dish is only rocked, fluctuation very little in the vertical direction, it is ensured that the stable movement of oscillating uniform device Property and excellent shake up effect.
Brief description of the drawings
It is described in detail by way of example, and not by way of limitation with reference to the accompanying drawings hereinafter more of the present utility model specific real Apply example.Identical reference denotes same or similar part or part in accompanying drawing.It should be appreciated by those skilled in the art that What these accompanying drawings were not necessarily drawn to scale.In accompanying drawing:
Fig. 1 is the schematic diagram of the oscillating uniform device according to the utility model one embodiment;
Fig. 2 is the schematic partial structurtes explosive view of the oscillating uniform device according to the utility model one embodiment;
Fig. 3 is the schematic diagram of the Ames test instrument according to the utility model one embodiment;
Fig. 4 is the schematic local structural graph of the Ames test instrument according to the utility model one embodiment;
Fig. 5 is the signal of culture dish storage sorting equipment in the Ames test instrument according to the utility model one embodiment Property structure chart;
Fig. 6 is the schematic local structural graph of the Ames test instrument according to the utility model one embodiment.
Embodiment
To make the purpose, technical scheme and advantage of the utility model embodiment clearer, below in conjunction with accompanying drawing to tool Body embodiment is described in detail.In the utility model embodiment it should be noted that some pipelines in the example shown only by Portions are shown, some pipelines have been not shown in figure.
Fig. 1 is the schematic diagram of the oscillating uniform device 500 according to the utility model one embodiment, as shown in Figure 1 simultaneously With reference to Fig. 2, the utility model embodiment provides a kind of oscillating uniform device 500 for Ames test instrument.The oscillating uniform device 500 Including base 510, driving wheel 520, driven pulley 530 and shaking-up frame 540.Driving wheel 520 and driven pulley 530 are rotatably mounted In base 510.Shaking-up frame 540 is rotatably installed on driving wheel 520 and driven pulley 530 respectively at two position.Especially Ground, in this embodiment, base 510, driving wheel 520, driven pulley 530 and shaking-up frame 540 collectively form crank and rocker mechanism or Parallel-crank mechanism, it is directly or indirectly placed thereon to make shaking-up frame 540 at least drive when driving wheel 520 is rotated Culture dish is moved, so that many kinds of substance in culture dish is well mixed.
In some embodiments of the present utility model, shaking-up frame 540 include substrate 541, substrate 541 in its lower surface two Individual position is rotatably installed on driving wheel 520 and driven pulley 530 respectively.For example, substrate 541 is in two portions of its lower surface Turn hole is offered at position;Oscillating uniform device 500 also includes two rollers 580, is respectively arranged in driving wheel 520 and driven pulley 530 Upper surface, and be located at respectively in two turn holes.
In some embodiments of the present utility model, oscillating uniform device 500 also includes lowering or hoisting gear 550 and carrying disk 560.Rise Falling unit 550 is installed on shaking-up frame 540.Carrying disk 560 is used for culture dish holding, and is installed on lowering or hoisting gear 550, with lifting Elevating movement is carried out under the drive of device 550.Shaking-up frame 540 also includes side plate 542, and its upper end is arranged at one of substrate 541 On side, and lowering or hoisting gear 550 is installed on side plate 542.Carrying disk 560 is preferably sucker.Lowering or hoisting gear 550 can at least make culture The ware disk detachment of ware installs the ware disk stepped hole of culture dish, to prevent during rotationally, and stepped hole hinders the motion of ware disk. In some alternate embodiments of the present utility model, the ware disk of culture dish can be shifted on dynamic carrying disk 560 by other devices, because This in these embodiments, oscillating uniform device 500 can not have lowering or hoisting gear 550, and carrying disk 560 be directly mounted at shaking-up frame 540.
It is predetermined in order to more preferably and more accurately remove carrying disk 560 in some embodiments of the present utility model Position carries the ware disk of culture dish, and oscillating uniform device 500 also includes position detecting device 570, whether is configured to detection shaking-up frame 540 It is in or returns to initial position.For example, position detecting device 570 includes being installed on the signal patch and peace of the edge of substrate 541 Loaded on the sensor on base 510.
In order to further improve stability, the preferably common structure of base 510, driving wheel 520, driven pulley 530 and shaking-up frame 540 Into parallel-crank mechanism.And oscillating uniform device 500 also includes the first orientation lever 591 and the second orientation lever 592.First orientation lever 591 is horizontally extending, and is fixed on substrate 541, and parallel to the direction that driven pulley 530 is pointed to by driving wheel 520.The Two orientation levers 592 are horizontally extending, and are vertically arranged with the first orientation lever 591, and its one end is slidably mounted on First orientation lever 591, the other end is slidably mounted on base 510.
Fig. 3 is the schematic diagram of the Ames test instrument according to the utility model one embodiment, as shown in figure 3, And Fig. 4 to Fig. 6 is referred to, the utility model embodiment additionally provides a kind of Ames test instrument, and it may include pedestal 100, culture Dress is shaken up in ware storage sorting equipment 200, folding lid station apparatus 300 and sample adding system 400 and any of the above-described embodiment 500 are put, Ames test can be made to realize automation, on the basis of cost of labor is reduced, conventional efficient and reality is improved Test precision.
Culture dish storage sorting equipment 200 can be configured to is not added with the culture dish of mixed liquor one by one by what is deposited in it Ground is taken out, and after after addition mixed liquor in each culture dish, the culture dish is deposited in it.
Folding lid station apparatus 300, which can be configured to the movement for storing the drive culture dish of sorting equipment 200 using culture dish, to be made The ware disk and ware lid of culture dish depart from, and the ware disk of culture dish can be transported at each predetermined station.For example, folding lid work Position device 300 can ware disk ware lid folding station receive culture dish, then by ware disk be transported to mixed liquor addition station, also need by The ware disk of culture dish transports and is back to ware disk ware lid folding station etc..
Sample adding system 400 can be configured to a variety of solution and a kind of sample mixed, and the mixed liquor formed after mixing is defeated Deliver in the ware disk for adding station in mixed liquor.
The oscillating uniform device 500 is configured to add after mixed liquor in the ware disk of culture dish, drives the ware disk motion, from And it is well mixed the mixed liquor in the ware disk.
In some embodiments of the present utility model, culture dish storage sorting equipment 200 may include bottom plate 210, culture Ware frame 220 and elevating mechanism 230.
Bottom plate 210 can be a circular slab and be installed on pedestal 100, and through hole 211, the size of through hole 211 are offered thereon It may be slightly larger than or more than the diameter of culture dish, to allow culture dish to pass through.
Culture dish frame 220 is rotatably installed on bottom plate 210.Culture dish frame 220 can have multiple circumferences along bottom plate 210 The accommodating chamber of direction arrangement, each accommodating chamber vertically extends, and each accommodating chamber is when turning to the top of through hole 211 It is coaxial with through hole 211.A pile culture dish can be placed in each accommodating chamber.
Elevating mechanism 230 can have the support load portion 231 for being arranged at the lower section of through hole 211, and elevating mechanism 230 is configured to:
Support load portion 231 is moved upward in through hole 211 so that turn to through hole 211 it is coaxial, accommodate at least Culture dish in the accommodating chamber of one culture dish is located in support load portion 231, after move down support load portion 231, and make the receiving The upper surface of intracavitary, bottom culture dish is moved to upper table concordant with the upper surface of bottom plate 210 or less than bottom plate 210 The position in face so that in the accommodating chamber, the culture dish of bottom is sorted out;And/or
The support load portion 231 for carrying one or more culture dishes is moved up, and is made most lower in one or more culture dishes The lower surface of the culture dish of side is moved to the position of upper surface concordant with the upper surface of bottom plate 210 or higher than bottom plate 210, with One or more culture dishes are stored in turn in the accommodating chamber coaxial with through hole 211.
In some embodiments of the utility model embodiment, multiple accommodating chambers include at least one sorting accommodating chamber and At least one storage accommodating chamber, each sorting accommodating chamber is configured to deposit culture dish to be sorted, each storage accommodating chamber configuration Into storage culture dish to be stored.
When specifically used, first place one in each sorting accommodating chamber and pile up culture dish, each culture dish has ware lid and ware Disk.When needing singly to take out the culture dish in a sorting accommodating chamber, first it is moved upward to support load portion 231 logical In hole 211, make upper surface of the upper surface in support load portion 231 about with bottom plate 210 concordant.Culture dish frame 220 is rotated, makes the sorting Accommodating chamber turns to the top of through hole 211, due to the presence in support load portion 231, and the culture dish in the sorting accommodating chamber is located at support and carried In portion 231, it will not be fallen by through hole 211.Then, the slowly decline of support load portion 231 can be made with elevating mechanism 230.When the sorting is held Receive intracavitary, bottom culture dish upper surface be moved to it is concordant with the upper surface of bottom plate 210 or upper less than bottom plate 210 During position (be preferably concordant, be slightly above or below) on surface, stop declining, rotate culture dish frame 220, to prevent support When load portion 231 declines again, it is not necessary to which the culture dish of taking-up also falls.Followed by continuing to decline support load portion 231, make taking-up Culture dish depart from through hole 211 and culture dish frame 220, in order to which Ames test instrument carries out follow-up action.
, it is necessary to which the culture dish is stored after many kinds of substance is added in the culture dish of taking-up.Specifically, the culture dish is made In support load portion 231 in elevating mechanism 230, support load portion 231 carries the culture dish and moved up, when the upper surface of the culture dish The position for being moved to upper surface concordant with the upper surface of bottom plate 210 or less than bottom plate 210 (is preferably concordant, is slightly above or omits Less than) when, stop rising, rotate culture dish frame 220, so that a storage accommodating chamber is turned in the upper of through hole 211 Side.Then the lower surface of the culture dish is made to be moved to upper surface concordant with the upper surface of bottom plate 210 or higher than bottom plate 210 Position.Culture dish frame 220 is finally rotated, after preventing that support load portion 231 from declining, the culture dish in storage accommodating chamber falls.So Culture dish can be made to be stored in storage accommodating chamber.
Further, culture dish frame 220 may include multiple hack levers vertically extended, upper backup pad frame and lower support Grillage.Multiple hack levers limit multiple accommodating chambers, such as every four hack levers limit an accommodating chamber.Lower supporting plate frame and upper branch Fagging frame, is respectively arranged in the two ends of each hack lever.Elevating mechanism 230 may also include straight line slide unit, to drive in support load portion 231 Lower movement.It is preferably bracket or pallet to hold in the palm load portion 231.The lower section of bottom plate 210 is additionally provided with tumbler, is configured to drive culture Ware frame 220 is rotated.
Preferably, culture dish storage sorting equipment 200 also includes at least one collet 240, is arranged at each storage and accommodates The bottom of chamber, each collet 240 is configured to move in the presence of the culture dish that support load portion 231 is carried is moved up, to allow The culture dish that support load portion 231 is carried is moved upward to its top, and after the culture dish that support load portion 231 is carried is moved to above it Initial position is returned to, to hold in the palm the culture dish carried thereon.Such a setting can make the storing step of culture dish simpler, work as taking-up Culture dish in be added after many kinds of substance, it is necessary to when the culture dish is stored, a storage accommodating chamber is rotated everywhere In the top of through hole 211, the culture dish is then set to be in the support load portion 231 of elevating mechanism 230, support load portion 231 carries the training Foster ware is moved up, until the height in support load portion 231 is higher than collet 240, collet 240 first allows support load portion and culture dish to pass through, After return to initial position, then ask load portion 231 to decline, culture dish can be located on collet 240, such a structure can be easy to support load portion 231 whereabouts.Further, collet can also make have gap between a pile culture dish and bottom plate 210, be easy to user to take out culture Ware.Specifically, each collet includes at least three support columns, and one end of each support column is rotatably installed on a storage appearance Receive the bottom of chamber, be rotated up when being moved up with the culture dish carried in pallet, thus allow the culture dish that pallet is carried to On be moved to its top, and the culture dish carried in pallet be moved to above it after to it is lower rotation return to initial position, from And utilize its bar portion to support culture dish.
In some embodiments of the present utility model, folding lid station apparatus 300 may include support, upper disk 310 and station Rotating disk 320.Support is fixed on pedestal 100.Upper disk 310 is rotatably installed on support, and with multiple first step holes.Station Rotating disk 320 is rotatably installed on support and the lower section in upper disk 310, and has multiple second steps on station turnplate 320 Hole.Preferably, the quantity in first step hole and second step hole is equal.
The elevating mechanism 230 of culture dish storage sorting equipment 200 is configured to:A first step hole and one second When stepped hole is at coaxial position, the support load portion 231 for carrying culture dish is set to be moved down from the top of upper disk 310, so that support During load portion 231 sequentially passes through the first step hole and the second step hole, and the movement of support load portion 231, make culture dish Ware lid 720 is located at the first step hole and the ware disk 710 of culture dish is located at the second step hole, so that the ware lid of culture dish Separated with ware disk;The second step hole for carrying ware disk with the first step hole and one that ware lid is carried at one is in coaxial position During place, support load portion 231 is set to be moved up from the lower section of station turnplate 320, so that support load portion 231 sequentially passes through the second step hole With the first step hole, and during being moved in support load portion 231, the ware disk of culture dish is set to move up ware lid with culture dish Coordinate, so that the ware lid of culture dish is installed on ware disk.
That is, after elevating mechanism 230 takes out culture dish one by one, elevating mechanism 230 continues to decline, successively Through the first step hole in ware disk ware lid folding station and second step hole, ware lid 720 is set to be located at the platform in first step hole On terrace, ware disk 710 is located on the step surface in second step hole, ware disk is separated with ware lid.Then, 320 turns of station turnplate It is dynamic, ware disk is transported to mixed liquor addition station, sample adding system 400 conveys mixed liquor into ware disk 710, then station turnplate Ware dribbling is returned ware disk ware lid folding station by 320.Now, the support load portion 231 in the lower section of station turnplate 320 carries out ascending motion Ware lid is set to be covered on ware disk, continuing ascending motion makes culture dish be stored in culture dish storage sorting equipment 200.
In embodiment of the present utility model, station turnplate 320 and upper disk 310 need synchronous axial system, to ensure same training Support the ware disk of ware and the synchronism of ware lid.In such cases, ware disk ware lid folding station and mixed liquor addition station can same steppings Action is made, when being added mixed liquor, can also make another culture dish carry out the separation or combination of ware disk and ware lid.And And, the diameter of station turnplate 320 is more than upper disk 310, to prevent upper disk 310 from blocking the inconvenience caused to station turnplate 320 Mixed liquor is added in ware disk.
In this embodiment, after ware disk 710 is added mixed liquor in mixed liquor addition station, oscillating uniform device 500 can profit First make ware disk detachment second step hole with its lowering or hoisting gear 550, then drive ware disk to rock again.
In some embodiments of the present utility model, sample adding system 400 may include that multiple mixing test tubes 410, first drive Device, multiple samples storage test tube 420, sampler, multiple solution storage vessels 440 and solution withdrawing device.
First driving means are configured at least to make each mixing test tube 410 to be moved to the first station and the second station, and the One station and the second station are respectively at two positions.
Multiple sample storage test tubes 420 are respectively used to hold a variety of samples.
Sampler can be configured to take out sample from sample storage test tube 420 and be delivered to the sample of taking-up from In in the mixing test tube 410 of the first station.Sampler may be additionally configured to take out mixed liquor out of a mixing test tube 410, so The mixed liquor of taking-up is transported to afterwards in the ware disk for adding station in mixed liquor.
Multiple solution storage vessels 440 are respectively used to hold a variety of solution.
Solution withdrawing device is configured to take out the solution in multiple solution storage vessels 440 and defeated in a predetermined sequence Deliver in the mixing test tube 410 in the second station.
In this embodiment, first driving means are configured to make each mixing test tube 410 first be moved to the first station, First station is moved to the second station after receiving a kind of sample, to receive a variety of solution.Using multiple mixing test tubes 410 and first Drive device, can make a mixing test tube 410 be moved to the first station and the second station, receive a variety of solution and a sample is deposited The sample in test tube 420 is stored up, to form a kind of mixed liquor.Then, can make another mix test tube 410 be moved to the first station and Second station, receives another sample in a variety of samples and another sample storage test tube 420, to form another mixed liquor. Multiple mixing test tubes 410 can form a variety of mixed liquors.In this embodiment, first driving means are configured to make multiple adjacent Mixing test tube 410 is moved to the first station successively, and same sample is received in the first station, and difference is many of the sample received It is few inconsistent, to form sample gradient;After be moved to the second station, to receive a variety of solution.Using multiple mixing Hes of test tube 410 First driving means significantly improve conventional efficient.
In some embodiments of the present utility model, multiple samples store test tube 420 and are arranged at intervals along a circumferencial direction.Take Sampling device may include sampling needle tubing, the first rotating lifting gear 431 and the first plunger pump 432.First rotating lifting gear 431 is matched somebody with somebody It is set to the top at least driving sampling needle tubing to turn to the mixing test tube 410 in the first station or each sample storage test tube 420 top, and be configured to drive sampling needle tubing to carry out elevating movement.First plunger pump 432 is via pipeline and sampling needle tubing Connection, so that sampling needle tubing sucks sample and the sample for making to enter in sampling needle tubing from sampling from a sample storage test tube 420 Spued in needle tubing to the mixing test tube 410 in the first station.
When needing to take out the sample in a sample storage test tube 420, it sampling needle tubing is turned to the sample and deposit The top of test tube 420 is stored up, sampling needle tubing is declined the lower section for stretching into solution in sample storage test tube 420, then controls First plunger pump 432 works, and the sample is stored the sample in test tube 420 and enters in sampling needle tubing.Secondly, rise and rotation takes Sample needle tubing, make its turn in the first station mixing test tube 410 top, then make sampling needle tubing decline, finally make into Enter the sample sampled in needle tubing to spue out of sampling needle tubing in the mixing test tube 410 of the first station, complete taking for sample Go out.
In some embodiments of the present utility model, solution withdrawing device includes the second rotating lifting gear 451, Duo Gequ Liquid needle tubing 452, the second plunger pump 453 and first flow path switching device.Second rotating lifting gear 451 is configured to drive and each taken Liquid needle tubing 452 turns to the top or the top of a solution storage vessel 440 of the mixing test tube 410 in the second station, with And be configured to drive and each take liquid needle tubing 452 to carry out elevating movement.Second plunger pump 453 is via pipeline with each taking liquid needle tubing 452 connections.First flow path switching device, which is configured to controllably to turn on one, takes the plunger pump 453 of liquid needle tubing 452 and second, with controllable Ground make the second plunger pump 453 promote it is each take liquid needle tubing 452 from inhalation solution in a solution storage vessel 440 and make enter should Take the solution in liquid needle tubing 452 to take in liquid needle tubing 452 from this to spue in the mixing test tube 410 of the second station.
When needing to take out a variety of solution, two ways can be passed through:Mode one, can make it is multiple take liquid needle tubing 452 be in it is many The top of individual solution storage vessel 440, then make it is multiple take liquid needle tubing 452 decline stretch into multiple solution storage vessels 440.The One flow passage selector device first makes one to take the plunger pump of liquid needle tubing 452 and second to turn on, so that this takes suction in liquid needle tubing 452 molten Liquid.Then second flow path switching device makes another take the plunger pump of liquid needle tubing 452 and second to turn on, so that this takes liquid needle tubing 452 Interior inhalation solution.The 3rd is set to take liquid needle tubing 452 to be turned on plunger pump followed by second flow path switching device, so that this takes liquid pin Inhalation solution in pipe 452.…….Until last takes suction in liquid needle tubing 452 to have after corresponding solution.Rise and rotate multiple Liquid needle tubing 452 is taken, makes multiple tops for taking liquid needle tubing 452 to turn to the mixing test tube 410 in the second station successively, at some Take liquid needle tubing 452 be in the mixing test tube 410 top when, first flow path switching device turns on this and takes liquid needle tubing 452 and second Plunger pump 453, so that this takes the solution in liquid needle tubing 452 to spue to the mixing test tube 410 in the second station.Mode two, can Make it is multiple take liquid needle tubing 452 be in multiple solution storage vessels 440 tops, then make it is multiple take liquid needle tubing 452 decline stretch into In multiple solution storage vessels 440.First flow path switching device first makes one to take the plunger pump of liquid needle tubing 452 and second to turn on, with This is set to take inhalation solution in liquid needle tubing 452.Rise and rotate it is multiple take liquid needle tubing 452, make inhalation solution takes 452 turns of liquid needle tubing Move to the top of the mixing test tube 410 in the second station, make this take the solution in liquid needle tubing 452 to spue in the second station Mixing test tube 410.Then multiple sampling needle tubings are rotated, make multiple to take liquid needle tubing 452 to be in multiple solution storage vessels 440 Top, then make it is multiple take liquid needle tubing 452 decline stretch into multiple solution storage vessels 440.First flow path switching device makes separately One takes the plunger pump of liquid needle tubing 452 and second to turn on, so that this takes inhalation solution in liquid needle tubing 452.Rise and rotate multiple take Liquid needle tubing 452, make inhalation solution takes liquid needle tubing 452 to turn to the top of the mixing test tube 410 in the second station, takes this Solution in liquid needle tubing 452 spues to the mixing test tube 410 in the second station.…….Until all solution storage vessels Solution in 440 is all removed and is put into the mixing test tube 410 in the second station.
In some embodiments of the present utility model, sampler may also include sample presentation needle tubing and second flow path switching dress Put.Sample presentation needle tubing is installed on the first rotating lifting gear 431, to turn to place under the drive of the first rotating lifting gear 431 Elevating movement is carried out in the top of the mixing test tube 410 of the first station, and under the drive of the first rotating lifting gear 431; And sample presentation needle tubing is connected via pipeline with the first plunger pump 432, mixed with being absorbed out of mixing test tube 410 in the first station Liquid.Second flow path switching device is configured to controllably turn on sample presentation needle tubing and the first plunger pump 432, or conducting sampling needle tubing and the One plunger pump 432.First plunger pump is configured to make the mixed liquor entered in sample presentation needle tubing spue to the ware disk of culture dish.
After each mixing test tube 410 receives a kind of sample in the first station, and the second station is moved to, and receives a variety of The first station is returned to after solution immediately, sample presentation needle tubing can carry out reciprocal elevating movement, so that many kinds of substance in mixing test tube 410 More uniform mixed liquor is formed, then the invisible spectro mixed liquor of the mixing is delivered in the ware disk of one or more culture dishes.
In some embodiments of the present utility model, sample adding system 400 also includes rinse bath.Second flow path switching device Import also controllably connects air compressor and supply-water pump by valving.Supply-water pump is additionally operable to provide cleaning to rinse bath Liquid, for example, the import of supply-water pump controllably joining water box or alcohol container.First rotating lifting gear 431 is configured to drive and taken Sample needle tubing and sample presentation needle tubing turn to the top of rinse bath, after drop in rinse bath.When needing cleaning, the first rotation and lifting Device 431 can make sampling needle tubing and sample presentation needle tubing is in the top of rinse bath, and supply-water pump can be noted into rinse bath and needle tubing respectively Enter water, to clean the inside and outside of needle tubing.Then, supply-water pump injects alcohol into rinse bath and needle tubing, finally, air compression Machine can inject air into needle tubing, to realize the cleaning to needle tubing.
In some embodiments of the present utility model, multiple mixing test tubes 410 are arranged at intervals along a circumferencial direction.First drives Dynamic device may include:Rotating cylinder, multiple mixing test tubes 410 are installed on rotating cylinder;Motor, is configured to drive Rotational Cylindrical Body is rotated.
In some embodiments of the present utility model, Ames test instrument may also include stamp device 600, be configured at place Mark is set in the wall outer surface of the ware disk of stamp station or bottom wall outer surface, caused with preventing from mark being arranged at ware covering It is chaotic.Specifically, stamp device 600 may include code seat, at least one sliding block, at least one stamp pen and cylinder.Code seat is installed In pedestal 100.At least one sliding block is slidably mounted on code seat.Each stamp pen is fixed on a sliding block, with cunning Block carries out stretching motion, so that the wall outer surface in the ware disk in stamp station sets mark.Cylinder arrangement is into controllably The stamp pen for making each sliding block be installed on the sliding block carries out stretching motion.Further, code seat includes hang plate and set The supporting plate being placed in below hang plate.At least one sliding block is installed on hang plate, to be carried out along the direction parallel to hang plate Stretching motion.The nib of each stamp pen obliquely downward, is arranged on the side wall of ware disk with will preferably mark.
Described above is only preferred embodiment of the present utility model, it is noted that for the common skill of the art For art personnel, on the premise of the utility model principle is not departed from, any improvements and modifications made also should be regarded as this reality With new protection domain.

Claims (10)

1. a kind of oscillating uniform device for Ames test instrument, it is characterised in that including:
Base;
Driving wheel, is rotatably installed on the base;
Driven pulley, is rotatably installed on the base;With
Shaking-up frame, the driving wheel and the driven pulley are rotatably installed at two position respectively;And
The base, the driving wheel, the driven pulley collectively form crank and rocker mechanism or parallel four side with the shaking-up frame Shape mechanism, to make the shaking-up frame at least drive culture dish directly or indirectly placed thereon when the driving wheel is rotated Motion, so that many kinds of substance in the culture dish is well mixed.
2. oscillating uniform device according to claim 1, it is characterised in that
The shaking-up frame includes substrate, and the substrate is rotatably installed on the master respectively at two positions of its lower surface Driving wheel and the driven pulley.
3. oscillating uniform device according to claim 2, it is characterised in that
The substrate offers turn hole at two positions of its lower surface;
The oscillating uniform device also includes two rollers, is respectively arranged in the upper surface of the driving wheel and the driven pulley, and divide Wei Yu not be in two turn holes.
4. oscillating uniform device according to claim 2, it is characterised in that also including lowering or hoisting gear and carrying disk, the lifting Device is installed on the shaking-up frame;
The carrying disk is used to place the culture dish, and is installed on the lowering or hoisting gear, with the drive of the lowering or hoisting gear Lower carry out elevating movement.
5. oscillating uniform device according to claim 4, it is characterised in that
The shaking-up frame also includes side plate, and its upper end is arranged on a side of the substrate, and the lowering or hoisting gear is installed In the side plate.
6. oscillating uniform device according to claim 4, it is characterised in that
The carrying disk is sucker.
7. oscillating uniform device according to claim 2, it is characterised in that also include:
Position detecting device, is configured to detect whether the shaking-up frame is in or returns to initial position.
8. oscillating uniform device according to claim 7, it is characterised in that
The position detecting device includes being installed on the signal patch of the edge of the substrate and the biography being installed on the base Sensor.
9. oscillating uniform device according to claim 2, it is characterised in that
The base, the driving wheel, the driven pulley and the shaking-up frame collectively form parallel-crank mechanism;And described shake Even device also includes:
First orientation lever, it is fixed on the substrate, and parallel to the direction that the driven pulley is pointed to by the driving wheel;
Second orientation lever, is vertically arranged with first orientation lever, and its one end is slidably mounted on first orientation lever, The other end is slidably mounted on the base.
10. a kind of Ames test instrument, it is characterised in that described comprising the oscillating uniform device any one of claim 1 to 9 Oscillating uniform device is configured to add after mixed liquor in the ware disk of culture dish, the ware disk motion is driven, so that in the ware disk Mixed liquor be well mixed.
CN201621082978.8U 2016-09-26 2016-09-26 Oscillating uniform device and Ames test instrument Active CN206408230U (en)

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Application Number Priority Date Filing Date Title
CN201621082978.8U CN206408230U (en) 2016-09-26 2016-09-26 Oscillating uniform device and Ames test instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621082978.8U CN206408230U (en) 2016-09-26 2016-09-26 Oscillating uniform device and Ames test instrument

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Publication Number Publication Date
CN206408230U true CN206408230U (en) 2017-08-15

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109520866A (en) * 2019-01-25 2019-03-26 河南交院工程技术有限公司 A kind of compression shear test device
CN109868209A (en) * 2019-04-17 2019-06-11 重庆医药高等专科学校 Mixing device for the detection of bacterial quantity in food and drug samples

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109520866A (en) * 2019-01-25 2019-03-26 河南交院工程技术有限公司 A kind of compression shear test device
CN109520866B (en) * 2019-01-25 2023-12-12 河南交通职业技术学院 Pressure shear test device
CN109868209A (en) * 2019-04-17 2019-06-11 重庆医药高等专科学校 Mixing device for the detection of bacterial quantity in food and drug samples
CN109868209B (en) * 2019-04-17 2022-04-15 重庆医药高等专科学校 A mixing device that is arranged in food medicine to examine bacterium quantity in appearance to detect

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