CN204909824U - Antibiotic applying ointment or plaster of medical restoration that contains EGF - Google Patents

Abstract

The utility model relates to a novel medical application, in particular to a medical repair antibacterial application containing EGF. It consists of a base layer, a dressing layer and a release layer, assembled sequentially from top to bottom. The dressing layer includes upper and lower layers, that is, a repair layer and an antibacterial layer. The repair layer is provided with epidermal growth factor (EGF), and the antibacterial layer is provided with nanometer silver ions. The medical repair antibacterial application containing EGF described in the utility model has both tissue repair and antibacterial and anti-inflammatory functions, can effectively promote the wound repair of epithelial tissue, prevent arteriovenous puncture, trauma, treatment, and skin scar formation after surgery, and at the same time , effective antibacterial on the wound surface, improves the comfort of the patient, and also provides good skin conditions for re-puncture.

Description

A kind of antibacterial plaster for medical repair containing EGF

technical field

The utility model relates to a novel medical application, in particular to a medical repair antibacterial application containing EGF.

Background technique

The repair and disposal of surgical wounds, treatment, and postoperative incisions are not ideal. Clinically, absorbent cotton or gauze is commonly used to bandage and cover external wounds and postoperative incisions, but scabbed wounds are easily torn during dressing changes, increasing pain scores, increasing the pain of patients, delaying the healing of trauma, and even leading to or Exacerbated the formation of skin scarring.

The effect of skin care on arteriovenous puncture is unsatisfactory. With the professional development of intravenous infusion care, large domestic hospitals have gradually established needle-free wards, and more inpatients choose indwelling needles for infusion treatment. However, skin care at the puncture site after treatment is not taken seriously.

The skin at the puncture site is particularly problematic in hemodialysis patients. Internal fistula is the access method of long-term hemodialysis for most patients with renal failure. Due to long-term and frequent arteriovenous puncture, clinically, the skin condition of such hemodialysis patients is very bad. If it cannot be treated in a timely and effective manner, the patient's The state of skin puncture will be forced into a vicious circle. Therefore, creating a convenient application that can effectively solve the problem of epithelial tissue repair is a sincere gospel for clinical hemodialysis patients.

There are several drawbacks to traditional applicator designs. For medical application, non-woven materials are mostly used, and the drug is physically infiltrated on the non-woven fabric, pasted on the affected area, and absorbed by the skin to exert the drug effect. But most of them are volatile, easy to fall off, and easy to pollute.

At present, the opening of the peeling layer or the so-called protective layer of the medical portable application on the market is in the middle of the application. Although the two-piece film layers overlap, because the opening is at the dressing layer, it is easy to touch during use. To the dressing layer and the wound site, causing secondary pollution.

At present, there are many types of repairing plaster products, some of which have the functions of anti-inflammatory and antibacterial, hemostasis and itching, and promoting repair, and there are low-efficiency, medium-efficiency, and high-efficiency. However, in the process of use, reactions such as tissue cytotoxicity and skin tissue allergy occurred, which did not have good biological safety and seriously affected the use and promotion of application.

Contents of the invention

In order to overcome the technical and medical defects of the existing design concepts, the purpose of the present invention is to provide a medical repair antibacterial patch containing EGF, which can provide a low-cost tissue repair and antibacterial patch for inpatients or outpatients. The medical application with anti-inflammatory function can prevent the formation of skin scars after arteriovenous puncture, trauma, treatment, and surgery, improve the comfort of patients, and create good skin conditions for re-punctures.

The EGF-containing antibacterial patch for medical repair includes a base layer (1), a dressing layer (2) and a peeling layer (3), which are assembled sequentially from top to bottom. The dressing layer includes upper and lower layers, including a repair layer and an antibacterial layer.

The repair layer adopts a safe formula, which is as follows:

Epidermal Growth Factor (EGF) 0.1~3%

Vitamin A0.02~2%

Vitamin E0.02~3%

Gelatin 5~25%

Cocoa butter 0.2~2%

Glycerin 2~5%

Hyaluronic acid 1~3%

Citric acid 0.5~4%

Add deionized water to 100%

The EGF is a small molecular protein widely present in human skin cells, and is mainly distributed in body fluids such as blood and saliva. It can promote the division of epithelial tissue cells and accelerate cell metabolism, thereby promoting skin renewal and repair, and maintaining skin elasticity and plumpness.

For the repair layer, according to the specific formula, vitamin A, vitamin E, gelatin, cocoa butter, glycerin, hyaluronic acid, and citric acid are dissolved in deionized water, heated to 40-70°C to obtain a transparent solution, and cooled to 5 After ~21°C, add EGF, mix and process to form a film. Such a film-like repair layer helps the application to be more docile to the wound. In addition, the nano-silver dressing layer can play a moisturizing role, prevent the volatilization of EGF, and help to achieve the desired drug effect.

The antibacterial layer adopts the nano-silver activated carbon fiber layer, which can play a broad-spectrum, strong and durable anti-inflammatory effect, which is beneficial to reduce the number of dressing changes. In addition, the adsorption advantages of the activated carbon fiber layer can effectively improve the efficacy of the drug, deal with exudate, and improve the patient's subjective comfort.

The base layer adopts microporous air-permeable and anti-allergic non-woven medical adhesive tape, which has the characteristics of less irritation, easy peeling, easy observation, and no trace, which can prevent tearing of scab wounds during dressing changes and increase the number of patients. pain score.

The peeling layer is one of thermoplastic polyurethane film or polyethylene film, which has low cost and is easy to be sterilized and disposed of.

The film of the peeling layer is divided into long film and short film. From left to right, the long film covers the left basal layer of the applicator, the entire dressing layer, and 3/5 of the right basal layer; the short film covers 4/5 of the right basal layer from right to left. In this way, the overlapping part of the two-piece film layer is on the right side of the application. Since the opening avoids the middle dressing layer, it is difficult to touch the dressing layer and the wound site during use, and avoids the possibility of secondary pollution of the wound.

The medical repair antibacterial patch containing EGF has an overall shape of a rectangle or a square, and the four corners are trimmed in a protective arc to protect the skin as much as possible from small details and maintain the patient's subjective feeling.

Description of drawings

Fig. 1 is the structural representation of the utility model.

Detailed ways

Referring to accompanying drawing 1, medical restoration antibacterial application of the present utility model. It includes a base layer 1, a dressing layer 2 and a release layer 3, which are assembled sequentially from top to bottom.

For the repair layer, according to the special formula, vitamin A, vitamin E, gelatin, cocoa butter, glycerin, hyaluronic acid and citric acid are dissolved in deionized water, heated to 40-70°C to obtain a transparent solution, and cooled to 5-70°C. Add EGF after 21°C, mix and process to form a film.

In the dressing layer, the repair layer is provided with epidermal growth factor (EGF), which is formed into a film by mixing; the antibacterial layer is provided with nano-silver ions, which are physically infiltrated into activated carbon fibers. The repair layer is covered on the antibacterial layer, which ensures the efficacy of the EGF layer and conforms to the repair concept of "moist healing".

The peeling layer, when in use, first tear off 1/2 of the short film of the peeling layer, then tear off 1/3 of the long film, touch it gently from the right side and then cover the wound, after removing the peeling layer, use the pulp of your thumb to Apply it evenly from the center to the periphery, without sticking to the wound, easy to loosen, and avoid secondary pollution and secondary trauma of the wound.

The embodiments are merely examples for clearly illustrating the present utility model, rather than limiting the implementation of the present invention. For those of ordinary skill in the art, other changes or changes in different forms can also be made on the basis of the above description. And the obvious changes or variations derived therefrom still fall within the scope of protection of the present utility model. .

Claims (9)

1. A medical repair antibacterial plaster containing EGF, characterized in that: the whole is composed of a base layer (1), a dressing layer (2) and a peeling layer (3), which are assembled sequentially from top to bottom, and the dressing layer includes There are two upper and lower layers, including a repair layer and an antibacterial layer. 2 . The medical repairing antibacterial patch containing EGF according to claim 1 , wherein the repairing layer contains Epidermal Growth Factor (EGF). 3. A kind of EGF-containing medical restoration antibacterial plaster according to claim 2, characterized in that: the ingredients contained therein are processed into a film. 4. A kind of EGF-containing medical restoration antibacterial plaster according to claim 1, characterized in that: the antibacterial layer is a nano-silver activated carbon fiber layer with antibacterial and anti-inflammatory properties. 5. A kind of EGF-containing medical restoration antibacterial application according to claim 1, characterized in that: the base layer is a microporous air-permeable transparent non-woven medical adhesive tape. 6. A kind of EGF-containing medical restoration antibacterial plaster according to claim 1, characterized in that: the peeling layer is one of thermoplastic polyurethane film or polyethylene film. 7. A kind of medical restoration antibacterial application containing EGF according to claim 6, is characterized in that: the film of peeling layer is divided into long film and short film, and long film covers the left side of application from left to right The basal layer, the entire dressing layer, and 3/5 of the right basal layer, and the short film covers 4/5 of the right basal layer from right to left. 8. A medical repair antibacterial plaster containing EGF according to claim 1, characterized in that: its total thickness is 0.2-0.7cm. 9. A medical repair antibacterial plaster containing EGF according to claim 1, characterized in that: the overall shape is a rectangle or a square, and the four corners are trimmed in a protective arc.