CN204892469U - Wash integrated equipment of chromatographic column - Google Patents
Wash integrated equipment of chromatographic column Download PDFInfo
- Publication number
- CN204892469U CN204892469U CN201520533240.8U CN201520533240U CN204892469U CN 204892469 U CN204892469 U CN 204892469U CN 201520533240 U CN201520533240 U CN 201520533240U CN 204892469 U CN204892469 U CN 204892469U
- Authority
- CN
- China
- Prior art keywords
- chromatographic column
- bottle
- solvent
- waste liquid
- solvent bottle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002904 solvent Substances 0.000 claims abstract description 58
- 238000004140 cleaning Methods 0.000 claims abstract description 33
- 239000007788 liquid Substances 0.000 claims abstract description 32
- 239000002699 waste material Substances 0.000 claims abstract description 22
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 21
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 15
- 239000007789 gas Substances 0.000 claims abstract description 14
- 238000005406 washing Methods 0.000 claims abstract description 8
- 239000003599 detergent Substances 0.000 claims description 16
- 229910052757 nitrogen Inorganic materials 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 206010020852 Hypertonia Diseases 0.000 abstract description 3
- 238000009835 boiling Methods 0.000 abstract description 3
- 239000012535 impurity Substances 0.000 abstract description 3
- 229910001873 dinitrogen Inorganic materials 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 5
- 108091006146 Channels Proteins 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000007792 gaseous phase Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000005501 phase interface Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
Landscapes
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The utility model discloses a wash integrated equipment of chromatographic column, it includes, and nitrogen gas lets in tub, solvent bottleholder, a plurality of solvent bottle, waste liquid bottle and chromatogram mount, and solvent bottle and waste liquid bottle set up respectively on the solvent bottleholder, nitrogen gas lets in the pipe and is linked together with each solvent bottle respectively, and the washing liquid export of solvent bottle is connected to through the wash line establishes the washing liquid entry of the chromatographic column on the chromatogram mount be equipped with the peristaltic pump of control washing liquid flow on the wash line, the washing liquid export of chromatographic column is connected to through the waste liquid pipeline the waste liquid entry of waste liquid bottle. This unitized chromatographic column belt cleaning device can use one or more solvents in proper order to the sample in the chromatographic column, the washing of impurity, solvent, active matter or high boiling point material in the sample, and the waste liquid can be collected, but the demonstration control of gases flow of manometer, prevent hypertonia to the influence of chromatographic column, the chromatographic column can be fixed to the chromatographic column mount, also does benefit to the flow of solvent, convenient operation.
Description
Technical field
The utility model belongs to analysis field, is specifically related to a kind of complexes cleaning chromatographic column.
Background technology
After chromatographic column uses the regular hour, the impurity in sample, sample, solvent, active matter or high boiling substance gather and cause chromatographic column to be polluted in the chromatography column, and column efficiency reduces, and separating effect is deteriorated.These pollutants can be got rid of by making solvent flow through chromatographic column, and correct cleaning method is: after adding the first solvent, to cleaning device pressurization, but lower than 20psi, will use and solvent flow rate can be kept lower than the maximum pressure of 1mL/min; Except the chromatographic column of most of 0.53mmm internal diameter, before flow velocity reaches 1mL/min, the pressure of cleaning device first will arrive 20psi; If use the solvent that proportion is comparatively large or viscosity is larger, or column diameter is little or length is long, then need longer scavenging period; All to enter or major part has entered after in chromatographic column until the first solvent, add lower a kind of solvent.After solvent to be cleaned flows out chromatographic column, the gas of pressurization is allowed to pass into chromatographic column 5-10 minute.Chromatographic column is loaded injection port and then passes into carrier gas.
Due to cleaning device inconvenient operation in the market, uncontrollable pressure and flow, change solvent back and forth also pretty troublesome, cleaning performance is bad, fragile chromatographic column, and solvent bottle is special, price.So the measure that common laboratory is taked intercepts contaminated plug, without what improve after intercepting, the chromatographic column directly more renewed, causes the wasting of resources and environmental pollution.
Summary of the invention
The purpose of this utility model has problems for existing cleaning device, provide a kind of complete chromatographic column cleaning device, it not only solves the control of gas pressure and solvent flux in cleaning process, avoid the damage of chromatographic column, and it is easy to operate, the alternative cleaning of multi-solvents, cleaning performance is good, thus solves the cleaning and regeneration of chromatographic column.
The technical solution of the utility model is:
A kind of complexes cleaning chromatographic column, it comprises nitrogen access tube, solvent bottle stand, multiple solvent bottle, waste liquid bottle and chromatogram fixed mount, described solvent bottle and waste liquid bottle are separately positioned on described solvent bottle stand, described nitrogen access tube is connected with each solvent bottle respectively, the rinse liquid outlet of solvent bottle is connected to the filter washing water inlet of the chromatographic column be located on described chromatogram fixed mount by detergent line, described detergent line is provided with the peristaltic pump controlling cleaning fluid flow; The rinse liquid outlet of described chromatographic column is connected to the waste liquid entrance of described waste liquid bottle by waste-solution line.
Preferably, nitrogen access tube is provided with gas control valve and Pressure gauge.Further, detergent line can be provided with the transfer valve that the cleaning fluid controlling different solvents bottle passes into chromatographic column.
In a kind of preferred version, the detergent line before peristaltic pump is provided with the multiple-pass joint detergent line being communicated with multiple solvent bottle being collected to peristaltic pump.
This device can comprise control system further, and this control system is connected with transfer valve with gas control valve, peristaltic pump respectively by control circuit.
The beneficial effects of the utility model:
This complete chromatographic column cleaning device can use one or more solvents successively to the flushing of the sample in chromatographic column, the impurity in sample, solvent, active matter or high boiling substance, waste liquid can collect, manometric display can control gas flow, prevent hypertonia on the impact of chromatographic column, chromatographic column fixed mount can stationary chromatographic post, also the flowing of solvent is beneficial to, handled easily.
Accompanying drawing explanation
Fig. 1 is a kind of structural representation of the present utility model.
Fig. 2 is another kind of structural representation of the present utility model.
In figure, 1-gas control valve; 2-transfer valve; 3-Pressure gauge; 4-solvent bottle stand; 5-solvent bottle; 6-waste liquid bottle; 7-chromatographic column fixed mount; 8-chromatographic column; 9-nitrogen access tube; 10-four-way connection; 11-peristaltic pump; 12-waste-solution line; 13-detergent line.
Detailed description of the invention
Below in conjunction with drawings and Examples, the utility model is further described.
As shown in the figure, the complexes of this cleaning chromatographic column comprise nitrogen access tube 9, solvent bottle stand 4, multiple solvent bottle 5, waste liquid bottle 6 and chromatogram fixed mount 7, and solvent bottle 5 and waste liquid bottle 6 are separately positioned on solvent bottle stand 5.Nitrogen access tube 9 is connected with each solvent bottle 5 respectively, and nitrogen access tube 9 is provided with gas control valve 1 and Pressure gauge 3.The rinse liquid outlet of solvent bottle 5 is connected to the filter washing water inlet of the chromatographic column 8 be located on chromatogram fixed mount 7 by detergent line 13, detergent line 13 is provided with the peristaltic pump 11 controlling cleaning fluid flow; Detergent line 13 before peristaltic pump 11 is provided with the transfer valve 2 that the cleaning fluid controlling different solvents bottle passes into chromatographic column, the detergent line 13 between transfer valve 2 with peristaltic pump 11 is provided with the four-way connection 10 detergent line being communicated with multiple solvent bottle being collected to peristaltic pump.The rinse liquid outlet of chromatographic column 8 is connected to the waste liquid entrance of waste liquid bottle 6 by waste-solution line 12.
This device also can be assembled into integrated system as shown in Figure 1, installing gas control valve 1, transfer valve 2 and Pressure gauge 3 on valve body panel, solvent bottle stand has multiple receiving hole, one or more fresh solvent bottles 5 and waste liquid bottle 6 can be placed, chromatographic column fixed mount 7 can keep flat as required or vertically use, mix chromatographic column interface, solvent interface, air-path interface, just define the chromatographic column cleaning device that complete set is fixing.
Cleaning fluid pressure in this device controls to be controlled by cleaning solution upper gaseous phase interface bleed pressure, no matter uses one or more cleaning fluids, and gaseous pressure can realize unified control.Cleaning fluid enters chromatographic column speed and realizes 1ml/min constant flow control by converging the peristaltic pump after four-way connection.Multiple kinds of cleaning agent or purge gas enter and use button and solenoid control.This chromatographic column cleaning device can use one or more solvents to rinse polluter in chromatographic column successively; waste liquid can collect; manometric display can control gas flow; prevent hypertonia on the impact of chromatographic column; chromatographic column fixed mount can stationary chromatographic post; protection chromatographic column, easy to use.
If need multi-solvents to clean, then in multiple solvent bottle, put into different solvents successively, adopt button and magnetic valve to switch to corresponding solvent bottle.
If preset pattern, the control system or control circuit that are connected with gas control valve, peristaltic pump and transfer valve respectively can be introduced, as Small Scale Integration plate etc., preset the duration of channel sequence and each channel switch, realize a key operation, automatically clean.
Claims (5)
1. one kind is cleaned the complexes of chromatographic column, it is characterized in that comprising nitrogen access tube, solvent bottle stand, multiple solvent bottle, waste liquid bottle and chromatogram fixed mount, described solvent bottle and waste liquid bottle are separately positioned on described solvent bottle stand, described nitrogen access tube is connected with each solvent bottle respectively, the rinse liquid outlet of solvent bottle is connected to the filter washing water inlet of the chromatographic column be located on described chromatogram fixed mount by detergent line, described detergent line is provided with the peristaltic pump controlling cleaning fluid flow; The rinse liquid outlet of described chromatographic column is connected to the waste liquid entrance of described waste liquid bottle by waste-solution line.
2. the complexes of cleaning chromatographic column according to claim 1, is characterized in that being provided with gas control valve and Pressure gauge on described nitrogen access tube.
3. the complexes of cleaning chromatographic column according to claim 2, is characterized in that in described detergent line, be provided with the transfer valve that the cleaning fluid controlling different solvents bottle passes into chromatographic column.
4. the complexes of cleaning chromatographic column according to claim 1, is characterized in that the detergent line before described peristaltic pump being provided with the multiple-pass joint detergent line being communicated with multiple solvent bottle being collected to peristaltic pump.
5. the complexes of cleaning chromatographic column according to claim 3, is characterized in that it comprises control system, and this control system is connected with transfer valve with gas control valve, peristaltic pump respectively by control circuit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520533240.8U CN204892469U (en) | 2015-07-21 | 2015-07-21 | Wash integrated equipment of chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520533240.8U CN204892469U (en) | 2015-07-21 | 2015-07-21 | Wash integrated equipment of chromatographic column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204892469U true CN204892469U (en) | 2015-12-23 |
Family
ID=54914683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520533240.8U Expired - Fee Related CN204892469U (en) | 2015-07-21 | 2015-07-21 | Wash integrated equipment of chromatographic column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204892469U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112630318A (en) * | 2020-11-23 | 2021-04-09 | 江苏同济分析仪器有限公司 | Online cleaning pump of liquid chromatograph |
| US20220062957A1 (en) * | 2019-04-02 | 2022-03-03 | Daingl Tech Co., Ltd. | Gc column cleaner |
-
2015
- 2015-07-21 CN CN201520533240.8U patent/CN204892469U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220062957A1 (en) * | 2019-04-02 | 2022-03-03 | Daingl Tech Co., Ltd. | Gc column cleaner |
| EP3951383A4 (en) * | 2019-04-02 | 2024-02-21 | Daingl Tech Co., Ltd. | Gc column cleaner |
| CN112630318A (en) * | 2020-11-23 | 2021-04-09 | 江苏同济分析仪器有限公司 | Online cleaning pump of liquid chromatograph |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151223 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |