CN204734576U - Contamination double atomization device is breathed to liquid aerosol - Google Patents

Abstract

The utility model relates to a two-stage atomization device for liquid aerosol respiratory poisoning, which is characterized in that the two-stage atomization device includes a first-stage atomization device and a second-stage atomization device, and the first-stage atomization device is an electroacoustic Transducer type ultrasonic atomization device, the secondary atomization device is a pneumatic atomization device, wherein, the primary atomization device and the secondary atomization device are configured so that the electroacoustic transduction type ultrasonic atomization The droplets atomized by the ultrasonic atomization device are sent to the pneumatic atomization device for further crushing, and finally output the liquid aerosol.

Description

Two-stage atomization device for liquid aerosol respiratory exposure

technical field

The utility model relates to a liquid aerosol respiratory poisoning two-stage atomization device, which belongs to the field of animal drug delivery devices.

Background technique

Liquid aerosol exposure is the specific application of liquid atomization technology in toxicology research, which is used to explore the toxic effects of substances on animals through the respiratory route. At present, liquid atomization can be summarized into three ways: mechanical atomization, pneumatic atomization and ultrasonic atomization.

Mechanical atomization achieves atomization by pressurizing the liquid to spray it out at high speed, without the need to add energy from other atomizers. The average particle size of the atomization is large, and it is generally difficult to enter the lungs of animals or humans. Pneumatic atomization uses a certain pressure of gas as an energy carrier to atomize the liquid by impacting or tearing it in various ways. Although the atomized particles of a specific particle size are finer, the liquid handling capacity of a single atomizing nozzle Small, due to its structural principle, the atomization amount of a single nozzle cannot be controlled while maintaining the particle size. Ultrasonic atomization is the use of ultrasonic waves to strengthen the decomposition and atomization of liquids. It is divided into two types: electroacoustic transducer type and fluid dynamic type. The terminal voltage is realized, and the latter uses the fluid as the power source, and uses the kinetic energy of the high-speed fluid to emit ultrasonic waves. The advantage of the two types is that the liquid processing capacity is large, and the disadvantage is that the particle size distribution of the generated droplets is discrete.

The average particle size of aerosol particles produced by the above different liquid atomization methods is different, and the pneumatic atomization and electroacoustic transduction ultrasonic atomization devices are mainly used for clinical respiratory drug delivery. For animal poisoning experiments, especially for carrying out liquid aerosol fixed particle size range and fixed dose animal poisoning experiments, there is currently no good device and method to achieve this.

Cited documents and materials:

Dong Weiguang. Classification, principle and common failure analysis of atomized inhalers[J].Medical Equipment.2013 Issue 6, page 69.

Chen Wei. Intelligent atomizer[D]. Central South University. December 2004.

Guo Xilong. Study on the regularity and influencing factors of particle deposition in human lungs[D]. Central South University. May 2013.

Wang Zhentao, Cen Qigang, Luo Tigan.Experiment on atomization characteristics of two-fluid nozzle[J].Chemical Engineering.2010, No.2, p.26.

Liang Kunfeng, Wang Lin, Ruan Chunlei, Xu Bin. The mode of liquid-liquid dispersion and atomization to form droplets[J]. Chinese Journal of Process Engineering. 2013, Issue 5, p. 735.

Huang Hui, Yao Xi, Wang Minqiang, Wu Xiaoqing. Atomization Performance Test of Ultrasonic Atomization System[J]. Piezoelectricity and Acousto-Optics. 2004, Issue 1, p. 62.

Yao Yue. The Mechanism and Experimental Study of Pneumatic Atomization of High Viscosity Fluid[D]. Zhejiang University. February 2006.

Zhao Yulong. Experimental research on the influence of viscosity and surface tension on atomization effect[D]. Northeastern University. June 2012.

Lu Ping, Liang Xiaoyan, Zhang Mingyao.Experimental Research on Atomization Characteristics of Two-Fluid Nozzle[J].Journal of Nanjing Normal University (Engineering Technology Edition).2008, No.1, p.34

Utility model content:

In order to solve the above problems, the inventor of this utility model designed a device that can combine electro-acoustic transducer ultrasonic atomization and pneumatic atomization to form a two-stage atomization device, and adjust the main factors affecting the two-stage atomization respectively To control the mass concentration, flow rate and particle size range of the final output liquid aerosol of the device, to ensure that smaller particles within a specific particle size range can enter different parts of the respiratory system of experimental animals.

The basic principle of the utility model device is to combine the pneumatic atomization of the two-fluid nozzle with the Venturi effect and the piezoelectric ceramic ultrasonic atomization, which can simultaneously adjust and control the mass concentration, flow rate and particle size range of the aerosol. It can effectively solve the problem of limited atomization amount and discrete particle size distribution of liquid aerosol after atomization, and is convenient for application in animal respiratory exposure experiments.

Specifically, the utility model provides a two-stage atomization device for liquid aerosol respiratory poisoning, the two-stage atomization device includes a primary atomization device and a secondary atomization device, and the primary atomization device is An electroacoustic transducing type ultrasonic atomization device, the secondary atomizing device is a pneumatic atomizing device, wherein the primary atomizing device and the secondary atomizing device are configured so that through the electroacoustic transducing type The ultrasonically atomized droplets of the ultrasonic atomizing device are sent to the pneumatic atomizing device for further crushing, and finally output the liquid aerosol.

In one embodiment, the two-stage atomization device further includes a voltage controller for controlling the voltage applied to the electroacoustic transducer type ultrasonic atomization device.

Preferably, the voltage controller is a digital voltage controller.

In another embodiment, the two-stage atomization device further comprises a flow control device for controlling the flow of air through the pneumatic atomization device.

Preferably, the flow control device is an electronic flow switch with a flow meter (19), so that a specific air flow value can be adjusted and/or set.

In yet another embodiment, the pneumatic atomizing device has inner and outer concentric nozzles (5), (7), and a gap control for controlling the gap size between the inner and outer concentric nozzles (5), (7) The device is carried out.

Preferably, the gap control device is a stepping motor (3) with a stepping motor controller.

In another embodiment, the two-stage atomization device further includes an infinite cycle time controller for setting and controlling the operating time of the two-stage atomization device.

Description of drawings

Fig. 1 is the appearance schematic diagram of the utility model;

Fig. 2 is the internal structure figure of the utility model;

Fig. 3 is a functional structural diagram of the utility model.

Reference signs:

1——handle 2——controller 3——stepper motor 4——screw

5——inner nozzle 6——aerosol outlet 7——outer nozzle 8——ultrasonic atomization chamber

9——Liquid solenoid valve 10——Liquid level control electrode 11——Piezoelectric ceramic atomizer base

12——Insert radiator 13——Axial flow blower 14——Hose 15——Medicine tank

16——Casters 17——Peristaltic pump 18——Air flow regulating valve, gas solenoid valve

19——Electronic flowmeter 20——Regulator valve, pressure switch 21——Air storage tank

22——air inlet 23——air filter 24——vibration damping column

25——Air compressor 26——Muffler shell 27——Water-cooled heat exchanger

28——Axial fan 29——Semiconductor cooling sheet 30——Water pump

31—Muffler

Detailed ways

The liquid aerosol respiratory poisoning two-stage atomization device of the present utility model is described in detail below in conjunction with the accompanying drawings.

In a specific embodiment of the present utility model, the two-stage atomization device includes a power supply, a stepping motor controller, an electronic flow switch, a liquid level switch, an infinite cycle time controller, an air compressor (25), a stepping motor (3), peristaltic pump (17), time control switch, solenoid valve (18), axial flow fan (28), ultrasonic power generator, digital voltage controller, piezoelectric ceramic atomizing sheet.

In the actual working process, the generation of liquid aerosol adopts two-stage atomization, that is, the combination of two different atomization methods. ①First-stage atomization realizes the transformation from liquid to droplets through piezoelectric ceramic ultrasonic atomization. Ultrasonic atomization uses ultrasonic waves as the energy source, and the high-frequency current is generated by the power generator. After passing through the piezoelectric ceramic transducer installed at the bottom of the atomization chamber, the high-frequency current is converted into sound waves to act on the liquid in the atomization chamber through resonance. The vibration of ultrasonic waves breaks the liquid into mist droplets. ②Secondary atomization Through pneumatic atomization, the compressed gas can further control the droplets of the primary atomization. Pneumatic atomization uses gas kinetic energy as the energy source, and the high-speed airflow is generated by the gas compressor, and the droplets are accelerated along with it. During the accelerated movement, the balance of aerodynamic force and surface tension acting on the droplets is destroyed, and the droplets are further broken.

In two-stage atomization, the greater the velocity difference between the droplets and the gas at the nozzle, the easier it is for the droplets to break into smaller particle sizes. Therefore, the atomization effect can be affected by controlling the speed difference between the mist and the gas. In the first-stage atomization, when the current frequency is fixed, the amount of liquid atomization increases with the increase of the voltage, while in the second-stage atomization, the air flow affects the aerosol mass flow. Since the speed difference between the droplets and the gas in the secondary atomization can also affect the atomization effect, the atomization effect is also affected by the size of the gap between the concentric nozzles inside and outside the secondary atomization chamber and the air flow rate.

It can be seen that the concentration, flow rate and particle size range of the final output aerosol of the device can be adjusted and controlled through the mutual adaptation and coordination of the voltage, air flow rate and the gap between the inner and outer concentric nozzles.

The connecting pipeline between the primary atomizing device and the secondary atomizing device should not be too long. On the premise of ensuring less loss when the droplets pass through the pipeline, as long as it is constructed so that the electroacoustic transducing ultrasonic atomization The droplets after ultrasonic atomization by the device are sent to the pneumatic atomization device for further crushing, and finally output the liquid aerosol.

in particular:

The stepping motor (3) is fixed at the secondary atomizing nozzle, and is connected with the outer nozzle (7) through the screw (4). The stepping motor controller realizes the migration of the outer nozzle by controlling the positive and negative rotation of the stepping motor and the rotation angle The movement changes the size of the gap between the inner and outer nozzles, and then affects the speed difference between the compressed air and the liquid aerosol particles at the mouth of the inner nozzle (5), so as to achieve the expected crushing effect.

The specific air flow value is adjusted and set by an electronic flow switch with a flow meter (19).

The liquid level switch with the liquid level control electrode (10) controls whether the peristaltic pump (17) pumps liquid medicine into the atomization chamber (8) according to the on-off current between the electrodes when they are submerged in automatic mode. The rate and direction of the liquid delivered by the peristaltic pump (17) are controlled by another stepper motor controller.

The two-stage atomization works together. In the first-stage atomization, that is, ultrasonic atomization, the time-controlled switch controls the total working time of the ultrasonic power generator, and the digital voltage controller controls the voltage distributed by the ultrasonic power generator to the piezoelectric ceramic atomizer. , the normally closed liquid solenoid valve (9) is opened, and the axial flow fan (28) starts to work, blowing away the ultrasonically atomized mist and sending it to the secondary atomizing nozzle. In the secondary atomization, that is, pneumatic atomization, the opening or closing of the air compressor (25) is only controlled by the pressure switch. When the pressure in the air storage tank (21) drops to a certain value, the air compressor (25) automatically Work. The air pressure output by the air storage tank (21) is controlled by a voltage regulator, the air flow is controlled by an electronic flow switch, and the normally closed gas solenoid valve (18) determines whether the compressed air flows through the secondary atomizing nozzle during the secondary atomization. The secondary atomizing nozzle consists of a concentric inner nozzle (5) and an outer nozzle (7). Since pneumatic atomization is powered by compressed air to spray and atomize the liquid medicine, the effect of the secondary atomization can be controlled by adjusting the gap between the inner and outer concentric nozzles and the air flow.

The working parts of the above-mentioned primary atomization and secondary atomization work or stop at the same time, and the time interval is controlled by the infinite cycle time controller.

In particular, it should be pointed out that the bottom of the atomization chamber is connected with the base of the piezoelectric ceramic atomizer (11) by a screw. There is a rubber ring around the atomizer, which can prevent leakage after tightening. There are two symmetrically distributed rubber rings. two metal thimble contacts, and these two metal thimble contacts are respectively connected to the wires on the back of the piezoelectric ceramic atomizing sheet, and in addition, the back of the ceramic atomizing sheet is also connected to the insert radiator (12).

The procedure for using the device is described below.

Before using the device, take out the liquid medicine tank (15), and add a certain volume of liquid medicine therein.

Open the main power switch of device, air compressor (25) starts working, and when pressure reaches certain value in the air storage tank (21), air compressor (25) stops working. The pressure stabilizing valve decompresses the compressed air in the air storage tank (21) and stabilizes the output.

Set the voltage of the primary atomization, the air flow rate of the secondary atomization and the distance between inner and outer nozzles, and the controller (2) displays the set values. Please note that the controller (2) is a combination of a group of controllers, with digital voltage controller, electronic flow switch, stepper motor controller, time control switch and infinite cycle time controller, respectively used to set the primary fog The voltage of the atomization, the air flow of the secondary atomization, the distance between the inner and outer nozzles, the working time, and the working process.

Set the working interval and the total working time of the device, the controller displays the set working interval and the timing of the working time and starts to work automatically.

When there is no liquid between the liquid level control electrodes (10), the liquid level switch activates the peristaltic pump (17) to deliver the medicinal liquid to the ultrasonic atomization chamber (8) through the hose (14). When the medicinal liquid level reaches a certain height, the liquid level switch closes the peristaltic pump (17).

The piezoelectric ceramic atomizing sheet starts to work, and the axial flow blower (13) blows the air through the normally open liquid solenoid valve (9) to the ultrasonic atomization chamber (8) to send the aerosol after the first-stage atomization to the second-stage At the same time, the normally closed gas solenoid valve (18) is opened to allow compressed air to flow through the secondary atomizing nozzle, forming a liquid aerosol to be ejected from the aerosol outlet (6).

The intermittent operation of the device is carried out according to the set cycle. When the total working time of the device reaches the set value, the primary atomization will automatically stop and other processes will continue (continue to supply air to prevent suffocation of the poisoned object).

After poisoning finishes, the liquid medicine tank (15) is taken out, puts into the liquid medicine tank that 75% ethanol solution is housed and prepares cleaning device.

Turn off the wireless cycle time controller, press the liquid level switch to enter the cleaning stage, and the peristaltic pump (17) will continue to work to send the ethanol solution into the atomization chamber (8), and then overflow from the aerosol outlet 6 to collect the overflow liquid, so as to achieve the purpose of cleaning.

Turn off the main power switch of the device, unscrew the piezoceramic atomizing sheet base (11) with the insert radiator (12) connected to the ultrasonic power generator by means of the thimble contact, the remaining ethanol solution in the atomizing chamber flows out, Screw on the ceramic atomizer to complete cleaning.

When needing to clean at ordinary times, clear water or cleaning solutions such as ethanol can be loaded onto the medicinal solution tank (15), and the above-mentioned process is repeated to carry out empty loading, thereby reaching the purpose of cleaning.

When the accumulative working time of the ceramic atomizer has reached its lifespan, unscrew the piezoelectric ceramic atomizer base (11), remove the old atomizer, and replace it with a new atomizer when the main power supply of the device is turned off. piece.

In addition, the two-stage atomization device for liquid aerosol breathing and poisoning of the present invention also has a handle (1) and casters (16) for convenient use. Air inlet (22) place can be equipped with air filter (23) to purify compressed air. In addition, in order to reduce the noise of the air compressor, it can be equipped with a damping column (24) and a muffler (31). In addition, in order to avoid the overheating of the air compressor and its heat production to increase the temperature of the output compressed air and cause adverse effects on experimental animals, the air compressor is equipped with a water-cooled heat exchanger (27), an axial flow fan (28 ), semiconductor refrigeration sheet (29) and water pump (30) to keep the compressed air temperature of air compressor output in a certain range.

The utility model has the following effects:

1. Overcome the disadvantages of inconvenient operation of existing nebulizers in animal breathing exposure experiments, and at the same time control the concentration, flow rate and particle size range of aerosols.

2. After the poisoning process is over, the air compressor works as usual, which can avoid hypoxia or suffocation of experimental animals.

3. The device has the function of timing poisoning, which is convenient for long-term poisoning experiments.

4. The device has a cleaning function.

5. Piezoelectric ceramic atomizer is detachable and easy to replace.

6. There are finned radiators to dissipate heat more effectively on the atomizing fins.

The foregoing description of embodiments of the present invention have been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations will be apparent to those skilled in the art. The embodiments were chosen and described in order to best explain the principles of the invention and its practical application, thereby enabling others skilled in the art to understand various embodiments and various aspects of the invention as suited to the particular use contemplated. an improvement plan. The scope of the invention is defined by the following claims and their equivalents.

Claims (9)

1. liquid aersol breathes contamination double atomization device, it is characterized in that, described double atomization device comprises one-level atomising device and secondary atomising device, described one-level atomising device is electroacoustic transduction type supersonic atomizer, described secondary atomising device is pneumatic type atomising device, wherein, described one-level atomising device and secondary atomising device are constructed so that the droplet after described electroacoustic transduction type supersonic atomizer ultrasonic atomization is sent in described pneumatic type atomising device and carry out further fragmentation, and the described liquid aersol of final output.

2. double atomization device as claimed in claim 1, it is characterized in that, described double atomization device also comprises the voltage controller for controlling the voltage being applied to described electroacoustic transduction type supersonic atomizer.

3. double atomization device as claimed in claim 2, it is characterized in that, described voltage controller is digital voltage controller of rectification.

4. double atomization device as claimed in claim 1, it is characterized in that, described double atomization device also comprises the volume control device for controlling the air mass flow by described pneumatic type atomising device.

5. double atomization device as claimed in claim 4, it is characterized in that, described volume control device is the electronic flow switch with effusion meter (19), thus can adjust and/or set concrete air mass flow value.

6. double atomization device as claimed in claim 1, it is characterized in that, described pneumatic type atomising device has inside and outside concentric nozzle (5,7), and carry out for the gap control device controlling the gap length between described inside and outside concentric nozzle (5,7).

7. double atomization device as claimed in claim 6, it is characterized in that, described gap control device is the motor (3) with controllor for step-by-step motor.

8. double atomization device as claimed in claim 1, is characterized in that, described double atomization device also comprises the Infinite Cyclic time controller of running time for setting and control described double atomization device.

9. double atomization device as claimed in claim 1, it is characterized in that, described double atomization device comprises power supply, controllor for step-by-step motor, electronic flow switch, liquid-level switch, Infinite Cyclic time controller, air compressor (25), motor (3), peristaltic pump (17), time switch, electromagnetic valve (18), propeller fan (28), ultrasonic power generator, digital voltage controller of rectification, piezoelectric ceramic atomizer patch.