CN204274513U - For the sampler of sample collection in molecular diagnosis - Google Patents

Abstract

The utility model discloses a sampler for sample collection in molecular diagnosis, comprising an outer tube, a sampling head and a push rod, the outer tube has a lumen extending along the length direction of the outer tube, the sampling head includes a A detachable sampling head body at the lower end of the tube, the surface of the sampling head body has fluff for collecting samples; the push rod is slidably arranged in the lumen of the outer tube, and the upper end of the push rod is exposed on the Outside the outer tube, the lower end of the push rod is in contact with the sampling head, so that the push rod can separate the sampling head from the outer tube in a pushing manner under the action of an external force. Therefore, the collector of the utility model will not damage human tissue, and will not collect other costs such as protein. At the same time, the sample on the fluff is easier to separate than the cotton swab, and the detection result is more accurate and reliable. In addition, it is more convenient to use and has strong applicability.

Description

Samplers for sample collection in molecular diagnostics

technical field

The utility model relates to medical supplies, in particular to a sampler used for sample collection in molecular diagnosis.

Background technique

Molecular diagnosis is a technology that uses molecular biology methods to detect changes in the structure or expression level of genetic material in patients to make a diagnosis. Molecular diagnosis is the main method of predictive diagnosis. It can not only diagnose individual genetic diseases, but also prenatal diagnosis. The materials of molecular diagnosis include DNA, RNA and protein.

Reasonable specimen collection is crucial to ensure the integrity of specimens and the accuracy of qualitative/quantitative detection of nucleic acids. Specimens should be collected in strict accordance with appropriate biosafety guidelines. Improper specimen handling can lead to nucleic acid degradation and errors. patient test results. At present, when collecting samples, most of them use medical cotton swabs, which are easy to absorb protein components when collecting samples, and are not convenient for the separation of samples, which affects the accuracy of test results; at the same time, after collecting samples, the cotton swabs need to be cut The cotton swab head is placed in a centrifugal device to separate the sample, which is inconvenient to use; in addition, the cotton swab is not suitable for sample collection of the cervix and other parts, and its use is limited; again, the hardness of the cotton swab head is high, and it is difficult for the patient to use it. Cause pain and even destroy human tissue.

Utility model content

The purpose of the utility model is to overcome the deficiencies in the prior art and provide a sampler for sample collection in molecular diagnosis, which is easy to use, has good collection effect, and ensures the accuracy of detection and analysis results.

The technical solution adopted by the utility model to solve the problems of the prior art is: a sampler for sample collection in molecular diagnosis, comprising:

an outer tube having a lumen extending along the length of the outer tube;

A sampling head, the sampling head includes a sampling head body detachable from the lower end of the outer tube, the surface of the sampling head body has fluff for collecting samples;

a push rod, the push rod is slidably arranged in the lumen of the outer tube, and the upper end of the push rod is exposed outside the outer tube, and the lower end of the push rod is in contact with the sampling head so that the push rod can separate the sampling head from the outer tube in a pushing manner under the action of an external force.

Preferably, the sampling head body includes an integrally formed sampling part and a connecting part, the sampling part is suitable for being inserted into the inside of the part to be sampled on the human body, and the surface of the sampling part has the described fluff, and the connecting part and The lower ends of the outer tubes are plugged together.

Preferably, the connecting part is a columnar body, and the surface of the columnar body has at least two circles of annular protrusions, and the diameter of the annular protrusions is slightly larger than the inner diameter of the lumen at the lower end of the outer tube.

Preferably, the side of the sampling part protrudes to form a side stop, and the surface of the side stop has the fluff.

According to the sampler used for sample collection in molecular diagnosis provided by the utility model, the sampling head can be inserted into the part of the human body to be sampled, and the fluff on the sampling head can collect the required samples. Since the fluff has good flexibility, it will not Destroying human tissue will not collect other proteins and other costs. At the same time, the sample on the villi is easier to separate than the cotton swab, and the detection result is more accurate and reliable. After the collection is completed, the sampling head can be directly pushed down from the outer tube to the separation device by the push rod for separation, which is more convenient to use. In addition, the sampler can be replaced with different sampling heads according to different collection parts, so it has strong applicability. Furthermore, the fluff will not damage human tissues, reducing the pain of patients.

Description of drawings

Fig. 1 is a schematic front view of a sampler used for sample collection in molecular diagnosis according to an embodiment of the present invention;

Fig. 2 is a schematic side view of a sampler used for sample collection in molecular diagnosis according to an embodiment of the present invention;

Fig. 3 is a sectional view along A-A direction in Fig. 2;

Fig. 4 is a schematic side view of the sampling head in the sampler used for sample collection in molecular diagnosis according to the embodiment of the present invention;

Fig. 5 is a schematic front view of the sampling head in the sampler used for sample collection in molecular diagnosis according to the embodiment of the present invention;

Fig. 6 is a schematic diagram of another structure of the sampling head in the sampler used for sample collection in molecular diagnosis according to the embodiment of the present invention.

Reference signs:

outer tube 10;

Sampling head 20;

Sampling Department 201;

Side block 2011;

connection part 202;

Annular bump 2021;

fluff 203;

Putter 30.

The realization of the purpose of the utility model, functional characteristics and advantages will be further described in conjunction with the embodiments and with reference to the accompanying drawings.

Detailed ways

Embodiments of the present invention are described in detail below, examples of which are shown in the drawings, wherein the same or similar reference numerals designate the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary and are intended to explain the present invention and should not be construed as limiting the present invention.

In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", Orientation indicated by "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. The positional relationship is based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, Therefore, it should not be construed as limiting the invention.

Referring to FIG. 1 , the embodiment of the present invention provides a sampler for sample collection in molecular diagnosis, including an outer tube 10 , a sampling head 20 and a push rod 30 .

The outer tube 10 has a lumen extending along the length direction of the outer tube 10 . It can be seen that the outer tube 10 is generally cylindrical and can be made of environmentally friendly plastic materials that have no side effects on the human body.

The sampling head 20 includes a body of the sampling head 20 detachable from the lower end of the outer tube 10 , and the surface of the body of the sampling head 20 has fluff 203 for collecting samples. It should be noted that the body of the sampling head 20 is generally made of environmentally friendly plastic material, and the fluff 203 on its surface is fluff 203 with good flexibility, and the fluff 203 is densely covered on the surface of the sampling head 20 body. , in the production process, the surface of the sampling head 20 body is coated with viscose, and then the fluff 203 is adsorbed and stuck to the surface of the sampling head 20 body by electrostatic adsorption.

The push rod 30 is slidably arranged in the lumen of the outer tube 10, and the upper end of the push rod 30 is exposed outside the outer tube 10, and the lower end of the push rod 30 is in contact with the sampling head 20, so that the push rod 30 can separate the sampling head 20 from the outer tube 10 in a pushing manner under the action of an external force. That is to say, push the push rod 30 downwards, and the push rod 30 will exert a downward force on the sampling head 20, and finally the sampling head 20 will fall off from the lower end of the outer tube 10 under the action of the force. After the sampling is completed, the sampling head 20 can be detached from the lower end of the outer tube 10 in this way and put into the centrifuge device.

During specific use, the medical staff can hold the outer tube 10, insert the sampling head 20 into the part of the human body that needs to be collected, such as the oral cavity, etc. to collect samples, then move it to the top of the separation device, and push the push rod 30 downward with a little force. Make the push rod 30 to drop the sampling head 20 from the lower end of the outer tube 10, so that the sampling head 20 can fall into the separation device, and then use the separation device to separate.

According to the sampler used for sample collection in molecular diagnosis provided by the utility model, the sampling head 20 can be inserted into the human body to be sampled at 201 positions, and the fluff 203 on the sampling head 20 can collect the desired sample, because the fluff 203 has a good Therefore, it will not damage human tissue, and will not collect other proteins and other costs. At the same time, the sample on the fluff 203 is easier to separate than the cotton swab, and the detection result is more accurate and reliable. After the collection is completed, the sampling head 20 can be directly pushed down from the outer tube 10 to the separation device through the push rod 30 for separation, which is more convenient to use. In addition, the sampler can be replaced with different sampling heads 20 according to different collection parts, thus, the applicability is strong. Furthermore, the fluff 203 will not damage human tissues, reducing the pain of patients.

In a specific embodiment of the present utility model, the body of the sampling head 20 includes an integrally formed sampling part 201 and a connecting part 202, the sampling part 201 is suitable for being inserted into the inside of the part to be sampled 201 on the human body, and the surface of the sampling part 201 has the The above-mentioned fluff 203, the connecting portion 202 is inserted into the lower end of the outer tube 10. This plug-in structure is convenient for applying a downward thrust to the sampling part 201 through the push rod 30 after the sampling is completed, so that the sampling head 20 can be pushed out and separated from the outer tube 10 .

More advantageously, in an example of the present utility model, the connecting part 202 is a columnar body, and the surface of the columnar body has at least two rings of annular protrusions 2021, and the diameter of the annular protrusions 2021 is slightly larger than the inner diameter of the lumen at the lower end of the outer tube 10 . In this way, when the connecting part 202 is inserted into the lower end of the outer tube 10, the ring-shaped protrusion 2021 and the lower end of the outer tube 10 are tightly inserted to ensure a reliable connection between the sampling head 20 and the outer tube 10, and avoid any gap between the sampling head 20 and the outer tube 10. The detachable connection between them is too loose, which causes problems such as the sampling head 20 accidentally falling off during use.

It can be understood that the shape of the sampling part 201 can be designed according to the collected parts of the human body, so that the sampling part 201 is suitable for collecting samples from corresponding parts. For example, as shown in FIG. 4 and FIG. 5 , the sampling part 201 is a flat structure, and the thickness of the front end is slightly smaller than the thickness of the rear end.

In one embodiment of the present utility model, the side of the sampling part 201 protrudes to form a side stop part 2011 , and the surface of the side stop part 2011 has the fluff 203 . In this way, with this structure, when extending into the collection site of the human body (such as the cervix), the front end of the sampling part 201 extends into the internal sample of the collection site of the human body, while the side blocking part 2011 is outside the collection site of the human body (such as the outside of the cervix). Samples around the outside of the collection site of the human body (for example, the outside of the cervix) are collected through the side block 2011 .

In summary, according to the sampler used for sample collection in molecular diagnosis provided by the utility model, the sampling head 20 can be inserted into the human body to be sampled at 201, and the fluff 203 on the sampling head 20 can collect the required samples. Because the fluff 203 has good flexibility, it will not damage human tissue, and will not collect other proteins and other costs. At the same time, the sample on the fluff 203 is easier to separate than a cotton swab, and the detection result is more accurate and reliable. After the collection is completed, the sampling head 20 can be directly pushed down from the outer tube 10 to the separation device through the push rod 30 for separation, which is more convenient to use. In addition, the sampler can be replaced with different sampling heads 20 according to different collection parts, thus, the applicability is strong. Furthermore, the fluff 203 will not damage human tissues, reducing the pain of patients.

In the description of this specification, descriptions referring to the terms "one embodiment", "some embodiments", "example", "specific examples", or "some examples" mean that specific features described in connection with the embodiment or example , structure, material or characteristic is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be construed as limitations to the present invention. Variations, modifications, substitutions, and modifications to the above-described embodiments are possible within the scope of the present invention.

Claims (4)

1. for a sampler for sample collection in molecular diagnosis, it is characterized in that, comprising:

Outer tube, has the tube chamber extended along described outer tube length direction;

Sampling head, described sampling head comprises the sampling head body detachable with described outer tube lower end, and the surface of described sampling head body has the floss hair for collecting sample;

Push rod, described push rod is slidably disposed in the tube chamber of described outer tube, and the upper end of described push rod is emerging in the outside of described outer tube, the lower end of described push rod contacts with described sampling head, can be separated with outer tube by described sampling head in the mode of pushing under external force to make described push rod.

2. the sampler for sample collection in molecular diagnosis according to claim 1, it is characterized in that, described sampling head body comprises integrated sampling unit and connecting portion, described sampling unit is suitable for the inside of inserting position to be sampled on human body, and described sampling unit surface has described fine hair, the lower end of described connecting portion and described outer tube plugs.

3. the sampler for sample collection in molecular diagnosis according to claim 2, it is characterized in that, described connecting portion is column, and the surface of described column has at least two circle annular protrusions, and the diameter of described annular protrusion is slightly larger than the lumen diameter of described outer tube lower end.

4. the sampler for sample collection in molecular diagnosis according to claim 2, is characterized in that, the side of described sampling unit is outstanding is formed with side block portion, and surface, described side block portion has described fine hair.