CN203341867U - Individual intervertebral disc artificial nucleus prosthesis manufacturing device - Google Patents
Individual intervertebral disc artificial nucleus prosthesis manufacturing device Download PDFInfo
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- CN203341867U CN203341867U CN2013204369586U CN201320436958U CN203341867U CN 203341867 U CN203341867 U CN 203341867U CN 2013204369586 U CN2013204369586 U CN 2013204369586U CN 201320436958 U CN201320436958 U CN 201320436958U CN 203341867 U CN203341867 U CN 203341867U
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- artificial nucleus
- intervertebral disc
- printer
- nucleus prosthesis
- prosthese
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 18
- 238000009434 installation Methods 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 9
- 238000012545 processing Methods 0.000 claims description 9
- 239000000017 hydrogel Substances 0.000 claims description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 238000002591 computed tomography Methods 0.000 claims description 3
- 238000013421 nuclear magnetic resonance imaging Methods 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 238000006073 displacement reaction Methods 0.000 abstract description 6
- 238000007639 printing Methods 0.000 abstract description 5
- 208000021600 intervertebral disc degenerative disease Diseases 0.000 abstract description 4
- 210000004940 nucleus Anatomy 0.000 abstract 10
- 208000018650 Intervertebral disc disease Diseases 0.000 abstract 1
- 239000002861 polymer material Substances 0.000 abstract 1
- 238000013461 design Methods 0.000 description 8
- 238000002595 magnetic resonance imaging Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 206010044565 Tremor Diseases 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000007943 implant Substances 0.000 description 4
- 208000018180 degenerative disc disease Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- -1 for example Polymers 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 206010061246 Intervertebral disc degeneration Diseases 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000010017 direct printing Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000004927 fusion Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 210000000080 chela (arthropods) Anatomy 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000005786 degenerative changes Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002684 laminectomy Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
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- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The utility model relates to an individual intervertebral disc artificial nucleus prosthesis manufacturing device, which comprises an information collection instrument, a central processor and a 3D (three-dimensional) printer, wherein the information collection instrument is connected with the 3D printer via the central processor; the printing head of the 3D printer is provided with medical high polymer material; the manufactured artificial nucleus prosthesis is long-strip-shaped with the width of 2-6mm and the thickness of 5-9mm; the integral appearance of the manufactured individual intervertebral disc artificial nucleus is in the spiral state; the overall dimension of the spiral individual intervertebral disc artificial nucleus is characterized in that the longitudinal diameter is 8-22mm, and the lateral diameter is 18-38mm. According to the individual intervertebral disc artificial nucleus prosthesis manufacture device disclosed by the utility model, the artificial nucleus prosthesis conforming to the requirement can be individually manufactured according to the sizes of the nucleuses of different patients. The individual intervertebral disc artificial nucleus prosthesis manufacture device is used for treating lumbar intervertebral disc diseases, the problem that the practical requirement can not be satisfied because traditional artificial nucleus prosthesis with only several specifications can be manufactured is solved, and the problems of unstable intervertebral disc and displacement caused by that the size of the artificial nucleus prosthesis is unmatched are solved.
Description
Technical field
This utility model belongs to medical instruments field, relates to a kind of personalized intervertebral disc artificial nucleus prosthese manufacturing installation.
Background technology
Intervertebral disc is the vesselless tissue of human body maximum, is the high special structure consisted of multiple connective tissue, comprises vertebral pulp, fibrous ring and cartilage endplate, the physiological function that these structurally ordered rational arrangements are brought into normal play intervertebral disc.Due to extraneous factor or/and increase age the aging intervertebral disc generation degenerative change that makes extremely, its clinical manifestation is waist, the pain that has a pain in the leg, intervertebral disc afunction when serious.
At present, traditional therapy to the intervertebral disc degeneration illness is intervertebral disc marrow nuclear excising art or spinal fusion, the former needs the surgical removal vertebral pulp, the excision of functional nucleus pulposus will inevitably cause intervertebral height to reduce, very easily cause the original biomechanical property of intervertebral disc to be lost, potential the risk that causes intervertebral disc further to degenerate; The latter is because the skeletonization between soleplate has been brought out in the fusion of vertebral body, although can the stable disease zone, but reduced the range of movement of spinal column, because the compensation of spinal column can cause the generation of Adjacent segment degeneration, and because itself being a kind of Highly invasive art formula, operation wound is larger, though therefore above-mentioned two kinds of methods can be removed patient's pain to a certain extent, all exists such or such complication.
Reaching in time of 75 years, many surgeon and engineers and technicians attempt design, development artificial intervertebral disk, to maintain the mobility of pathological interspinal dish sections, prevent other sections intervertebral disc degeneration.The 3rd joint record of the chapter 13 in golden the earth, Qu Dongbin, Charles D.Ray chief editor " vertebral column intervertebral joint urethroptasty " according to the printing and publishing in June, 2004 of scientific and technical literature publishing house, nearly 100 kinds of artificial intervertebral disks are patented, but only a few is by platform load test, cadaver sample or animal Implantation Test, and the product that is put into clinical trial is very few.The 4th joint of this book provides a kind of lumbar intervertebral disc artificial nucleus prosthese, it is by the half mobility hydrogel nucleus of high-molecular polythene overcoat and Qi Nei (poly-the third ethylene nitrile-polyacrylamide copolymer), its profile is two kinds, wedge shape and rectangle, by Charles doctor D.Ray is invented, it is also at present unique clinical artificial nucleus prosthese that is applied to.Moisture that can the weight 80% of absorption own after the complete expansion of this intervertebral disc artificial nucleus, and its volume can change with load, during use and special-purpose fibrous ring expander, Laminoplasty spreader, prosthese examination film, implant guide, to hold the apparatuses such as prosthese pincers, round end propeller, elbow localizer supporting.The extensive use in Europe of above-mentioned lumbar intervertebral disc artificial nucleus prosthese, the existing 3000 many cases patients in the whole world have accepted this prosthese implant surgery.Postoperative follow-up investigation finds that its clinical effectiveness is not of great satisfaction yet, and the problem of existence is the prostheses migration of implanting; In addition, while implanting this lumbar intervertebral disc artificial nucleus prosthese, its art formula and conventional way of escape vertebral lamina fenestration, resection of nucleus pulposus are identical, the row laminectomy remove osseous tissue at least reach the wide service aisle of 12mm could the update apparatus, so wound is large.
For the problems referred to above, Chinese patent ZL200620020591.X has designed the artificial nucleus prosthese that a kind of percutaneous puncture is implanted intervertebral disc, this prosthese is elongated, integral body is bank position, uses this utility model not need surgical operation, the service aisle of setting up while utilizing percutaneous puncture to extract vertebral pulp, this utility model is pulled open, by service aisle, implant, simple to operate, wound is little; Do not affect intervertebral disc structure after implantation complete, good stability, can effectively guarantee the biomechanical function of normal disc after recovery.Although this kind of prosthese can overcome the large problem of wound of implanting of operating on, but because size, the form of human intervertebral disc are different, this kind of prosthese also just can roughly be made several specifications according to the measurement of human body, can not meet clinical actual requirement, and if prosthesis size is not inconsistent, easily bring a lot of drawbacks, for example shakiness, displacement etc. in the dish.Therefore, the needs design is a kind of can carry out according to different patient's characteristics the intervertebral disc artificial nucleus prosthese manufacturing installation of personalized designs.
The 3D printer, i.e. a kind of machine of Rapid Prototyping technique, it is that a kind of mathematical model file is basis, but uses the jointing materials such as powdery metal or plastics, carrys out the technology of constructed object by the mode of successively printing.Used is used to modeling in fields such as mould manufacture, industrial designs, existing just gradually for the direct manufacture of some products, means that this technology is universal.In medical field, perhaps can provide new approaches for personalized designs intervertebral disc artificial nucleus prosthese by the 3D printer applications.
Summary of the invention
The purpose of this utility model is to provide a kind of personalized intervertebral disc artificial nucleus prosthese manufacturing installation, and solving existing artificial nucleus prosthese can not carry out personalized designs according to patient's characteristics, easily because size is not inconsistent problems such as causing coiling interior shakiness, displacement.
This utility model is achieved through the following technical solutions: a kind of personalized intervertebral disc artificial nucleus prosthese manufacturing installation, this device comprises information acquiring instrument, central processing unit and 3D printer, information acquiring instrument is connected with the 3D printer by central processing unit, and the printhead of 3D printer is equipped with medical macromolecular materials; The artificial nucleus prosthese produced is strip, and width is 2-6mm, and thickness is 5-9mm, and overall appearance is bank position, and the overall dimensions after spiraling is that vertical diameter is 8-22mm, and trans D is 18-38mm.
Described information acquiring instrument is nuclear magnetic resonance imaging system (being called for short MRI) or computed tomography system (being called for short CT).
Described medical macromolecular materials are polyvinyl alcohol hydrogel.
As further improvement of the utility model, also comprise the data base, the data compilation that described data base is gathered by information acquiring instrument forms.
Adopt the good effect of technique scheme: this utility model can be produced satisfactory artificial nucleus prosthese according to different patients' vertebral pulp size personalization, be used for the treatment of lumbar vertebral disc disease, overcome existing artificial nucleus prosthese and can only produce fixing several specifications, can not meet the problem of actual needs, thereby solved because the artificial nucleus prosthesis size is not inconsistent the problems such as shakiness, displacement in the dish caused; In addition, the patient data collected is assembled into to the data base, is convenient to follow-up comparison work, if again run into the patient that data overlap, directly print nucleus prosthesis and get final product, do not need repetition work before, time saving and energy saving.
The accompanying drawing explanation
Fig. 1 is schematic diagram of the present utility model;
Fig. 2 is the artificial nucleus prosthese deployed condition schematic diagram produced;
Fig. 3 is the artificial nucleus prosthese that the produces view of spiraling.
In figure, 1 information acquiring instrument, 2 central processing units, 3 3D printers, 4 artificial nucleus prostheses, 5 data bases.
The specific embodiment
Below by embodiment and test example, the technical solution of the utility model is described further, but should not be construed as restriction of the present utility model:
Fig. 1 is schematic diagram of the present utility model, Fig. 2 is the artificial nucleus prosthese deployed condition schematic diagram produced, Fig. 3 is the artificial nucleus prosthese that the produces view of spiraling, shown in Fig. 1, Fig. 2, Fig. 3, a kind of personalized intervertebral disc artificial nucleus prosthese manufacturing installation, this device comprises information acquiring instrument 1, central processing unit 2 and 3D printer 3, and information acquiring instrument 1 is connected with 3D printer 3 by central processing unit 2, and the printhead of 3D printer 3 is equipped with medical macromolecular materials.Described information acquiring instrument 1 is nuclear magnetic resonance imaging system (being called for short MRI) or computed tomography system (being called for short CT), MRI and CT are for gathering the sized data of human body vertebral pulp, send 3D printer 3 to by central processing unit 2, for 3D printer 3 prints the artificial nucleus prosthese, provide the data basis.Medical macromolecular materials can be used some high polymers, for example, polyethylene, polypropylene etc., the medical macromolecular materials in this utility model are polyvinyl alcohol hydrogel, through clinical proof its to human body nonhazardous effect, be 50 years service life.The artificial nucleus prosthese 4 produced is strip, and width is 2-6mm, and thickness is 5-9mm, and overall appearance is bank position, and the overall dimensions after spiraling is that vertical diameter is 8-22mm, and trans D is 18-38mm.The advantage of this kind of artificial nucleus prosthese 4 is not need surgical operation, the artificial nucleus prosthese is pulled open, the service aisle of setting up while then utilizing percutaneous puncture to extract vertebral pulp is implanted, simple to operate, wound is little, and the artificial nucleus prosthese after implantation is spiral and is full of intercalated disc in intercalated disc, does not affect intervertebral disc structure complete, good stability, can effectively guarantee the biomechanical function of normal disc after recovery.
As further improvement of the utility model, also comprise data base 5, the data compilation that described data base 5 is gathered by information acquiring instrument 1 forms.Because whole manufacturing process is consuming time long, therefore, the benefit of making the data base is to store to a greater extent the patient data collected, when Resurvey arrives patient data, can be in advance with the data base in available data compare, and if existing data occur overlapping, do not need redesign, only need direct printing and making to get final product, time saving and energy saving.
A kind of personalized intervertebral disc artificial nucleus prosthese manufacture method, the method comprises the following steps:
(1) information acquiring instrument 1 image data, and be transferred to 3D printer 3 by central processing unit 2, for printing the artificial nucleus prosthese, the 3D printer provides the data basis;
(2) data that 3D printer 3 collects according to information acquiring instrument 1, by the medical macromolecular materials printing shaping, produce artificial nucleus prosthese 4;
(3) data that information acquiring instrument 1 collected are assembled into data base's 5 storages, for later work provides Data support, when Resurvey arrives patient data, can be in advance with the data base in available data compare, if and overlapping appears in existing data, do not need redesign, only need direct printing and making to get final product.
test example
The technical solution of the utility model is through the fresh cadaver test, and because fresh cadaver approaches the human normal state, result of study is reliable.Through MRI, corpse vertebral pulp size is measured, go out to meet the artificial nucleus prosthese of corpse vertebral pulp size according to this design data, after implanting in the corpse body by the artificial nucleus prosthese, MRI Resurvey data, with above-mentioned data, contrasted, find that prosthese is implanted rear and intervertebral disc is identical good, reach target in advance.Then corpse is dissected, after finding to implant, prosthese is without displacement or unstable phenomenon.
Verified, this utility model can carry out personalized designs according to the different size of patient's vertebral pulp, produce the artificial nucleus prosthese that precision meets patient's size, overcome the problem that artificial nucleus prosthese in the past only has several fixedly specifications, effectively prevented because prosthesis size is not inconsistent the problem such as shakiness, displacement in the dish of appearance.
Claims (4)
1. a personalized intervertebral disc artificial nucleus prosthese manufacturing installation, it is characterized in that: this device comprises information acquiring instrument (1), central processing unit (2) and 3D printer (3), information acquiring instrument (1) is connected with 3D printer (3) by central processing unit (2), and the printhead of 3D printer (3) is equipped with medical macromolecular materials; The artificial nucleus prosthese (4) produced is strip, and width is 2-6mm, and thickness is 5-9mm, and overall appearance is bank position, and the overall dimensions after spiraling is that vertical diameter is 8-22mm, and trans D is 18-38mm.
2. personalized intervertebral disc artificial nucleus prosthese manufacturing installation according to claim 1 is characterized in that: described information acquiring instrument (1) is nuclear magnetic resonance imaging system or computed tomography system.
3. personalized intervertebral disc artificial nucleus prosthese manufacturing installation according to claim 1, it is characterized in that: described medical macromolecular materials are polyvinyl alcohol hydrogel.
4. personalized intervertebral disc artificial nucleus prosthese manufacturing installation according to claim 1 is characterized in that: also comprise data base (5), the data compilation that described data base (5) is gathered by information acquiring instrument (1) forms.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013204369586U CN203341867U (en) | 2013-07-23 | 2013-07-23 | Individual intervertebral disc artificial nucleus prosthesis manufacturing device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013204369586U CN203341867U (en) | 2013-07-23 | 2013-07-23 | Individual intervertebral disc artificial nucleus prosthesis manufacturing device |
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| Publication Number | Publication Date |
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| CN203341867U true CN203341867U (en) | 2013-12-18 |
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| CN2013204369586U Expired - Fee Related CN203341867U (en) | 2013-07-23 | 2013-07-23 | Individual intervertebral disc artificial nucleus prosthesis manufacturing device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103340705A (en) * | 2013-07-23 | 2013-10-09 | 林杨 | Personalized lumbar intervertebral disc artificial nucleus prosthesis manufacturing device and method |
| CN105213038A (en) * | 2014-06-11 | 2016-01-06 | 三鼎生物科技股份有限公司 | Laminated printing device |
| US10675158B2 (en) | 2015-12-16 | 2020-06-09 | Nuvasive, Inc. | Porous spinal fusion implant |
-
2013
- 2013-07-23 CN CN2013204369586U patent/CN203341867U/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103340705A (en) * | 2013-07-23 | 2013-10-09 | 林杨 | Personalized lumbar intervertebral disc artificial nucleus prosthesis manufacturing device and method |
| WO2015010223A1 (en) * | 2013-07-23 | 2015-01-29 | Lin Yang | Apparatus and method for fabricating personalized intervertebral disc artificial nucleus prosthesis |
| CN103340705B (en) * | 2013-07-23 | 2015-05-20 | 林杨 | Personalized lumbar intervertebral disc artificial nucleus prosthesis manufacturing device and method |
| CN105213038A (en) * | 2014-06-11 | 2016-01-06 | 三鼎生物科技股份有限公司 | Laminated printing device |
| US10675158B2 (en) | 2015-12-16 | 2020-06-09 | Nuvasive, Inc. | Porous spinal fusion implant |
| US11660203B2 (en) | 2015-12-16 | 2023-05-30 | Nuvasive, Inc. | Porous spinal fusion implant |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131218 Termination date: 20150723 |
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| EXPY | Termination of patent right or utility model |