CN202920641U - Xiangdan injection production system - Google Patents
Xiangdan injection production system Download PDFInfo
- Publication number
- CN202920641U CN202920641U CN 201220587927 CN201220587927U CN202920641U CN 202920641 U CN202920641 U CN 202920641U CN 201220587927 CN201220587927 CN 201220587927 CN 201220587927 U CN201220587927 U CN 201220587927U CN 202920641 U CN202920641 U CN 202920641U
- Authority
- CN
- China
- Prior art keywords
- production
- decarburizing
- charcoal
- xiangdan
- filtration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 239000008886 xiangdan Substances 0.000 title claims abstract description 13
- 238000002347 injection Methods 0.000 title abstract 2
- 239000007924 injection Substances 0.000 title abstract 2
- 238000001914 filtration Methods 0.000 claims abstract description 17
- 238000002156 mixing Methods 0.000 claims abstract description 10
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 9
- 239000003610 charcoal Substances 0.000 claims description 9
- 238000010790 dilution Methods 0.000 claims description 9
- 239000012895 dilution Substances 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 6
- 239000000835 fiber Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 238000007865 diluting Methods 0.000 abstract 2
- 230000002411 adverse Effects 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000000706 filtrate Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000000243 solution Substances 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 210000004351 coronary vessel Anatomy 0.000 description 2
- 230000000916 dilatatory effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000004064 recycling Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000008899 fufang danshen Substances 0.000 description 1
- 231100000753 hepatic injury Toxicity 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The utility model relates to a Xiangdan injection production system which comprises an extracting system, a concentration preparing system, a decarburizing system, a diluting system, an acid-base blending system, a filtering system and an encapsulating system, wherein the extracting system is connected with the concentration preparing system which is connected with the decarburizing system, the decarburizing system is connected with the diluting system which is connected with the acid-base blending system, and the acid-base blending system is connected with the filtering system which is connected with the encapsulating system. Through the technical scheme, the defects that the present product has more adverse effects, is low in clarity and easily becomes yellow are overcome, the need of a client is well met, and the condition for mass production is completely achieved.
Description
Technical field
The utility model discloses a kind of production system of pharmaceutical formulation, what be specifically related to is the XIANGDAN ZHUSHEYE production system.
Background technology
XIANGDAN ZHUSHEYE claims again FUFANG DANSHEN ZHUSHEYE; through extracting refining forming by Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae two flavor Chinese medicines; have coronary artery dilating, increase the coronary blood liquid measure, the Ischemic myocardium anoxia, remove free radical, protection hepatic injury, calmness, improve the effect such as hemorheology, clinical application is many.XIANGDAN ZHUSHEYE is Chinese medicine preparation, and main component is Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae, has blood vessel dilating, promotes the effect of coronary artery blood flow, clinically is mainly used in angina pectoris, also can be used for the treatment of the diseases such as myocardial infarction.Increasingly extensive along with clinical practice, its Reporting of harms increases increasingly, and some reaction is more serious.
The utility model content
According to above-mentioned deficiency, the utility model discloses a kind of production system of XIANGDAN ZHUSHEYE.
For achieving the above object, the technical solution adopted in the utility model is a kind of production system of XIANGDAN ZHUSHEYE, the production technology of described XIANGDAN ZHUSHEYE comprises extraction system, dense match system, take off the charcoal system, dilution system, soda acid match system, filtration system and embedding system, wherein extraction system is connecting dense match system, dense match system is connecting the charcoal system taken off, take off the charcoal system and connecting dilution system, dilution system is connecting the soda acid mixing system, the soda acid mixing system is connecting filtration system, and filtration system is connecting the embedding system.
Described filtration system is comprised of defecator, and defecator is hollow fibre filtering.
After technique scheme, the untoward reaction that has solved present product is many, and clarity is bad, and the easy shortcoming such as jaundice has well satisfied client's needs, has possessed mass-produced condition fully.
Description of drawings
Fig. 1 is this utility model overall structure schematic diagram.
The specific embodiment
Below in conjunction with the drawings and specific embodiments, this utility model is described further.
By shown in Figure 1, this utility model is a kind of production system of XIANGDAN ZHUSHEYE, comprise extraction system 1, dense match system 2, take off charcoal system 3, dilution system 4, soda acid match system 5, filtration system 6 and embedding system 7, wherein extraction system 1 is connecting dense match system 2, dense match system 2 is connecting and is taking off charcoal system 3, takes off charcoal system 3 and is connecting dilution system 4, and dilution system 4 is connecting soda acid mixing system 5, soda acid mixing system 5 is connecting filtration system 6, and filtration system 6 is connecting embedding system 7; Described filtration system 6 is comprised of defecator, and defecator is hollow fibre filtering.
In specific operation process, operating procedure is as follows:
Get the Lignum Dalbergiae Odoriferae washing clean, add water infiltration, carry out steam distillation, get just distillate 2000ml, then carry out redistillation, get approximately 500ml of re-distilled liquid, cold preservation 24 hours divides the layer that deoils, and the another device of aqueous solution is collected standby.Get Radix Salviae Miltiorrhizae and choose decontamination, washing is clean, decocts with water three times, 2 hours for the first time, second and third time each 1.5 hours, collecting decoction, filter, filtrate is concentrated into approximately every 670-760ml, adds ethanol to make to contain the alcohol amount to reach 75%, standing, filter filtrate recycling ethanol, be concentrated into approximately 330ml, add again ethanol to make to contain the alcohol amount to reach 85%, standing, by volume add 1% active carbon in solution, stirred 1 hour, filter, filtrate recycling ethanol is concentrated into 200-300ml, add water for injection 1000-1650ml, standing, filter, filtrate is concentrated into approximately 330ml.Regulate pH value to 6.5-6.8 with 10% sodium hydroxide, boiled 1 hour, by volume add 1% active carbon in solution, boiled 15 minutes, filter, filtrate is regulated pH value to 6.8-7.0 with 10% sodium hydroxide solution again, injects water to approximately 500ml.Add the Lignum Dalbergiae Odoriferae distillate, mixing injects water and makes into 1000ml, through ultrafilter, filters inflated with nitrogen embedding, 100 ℃ of 2ml 30 minutes, 100 ℃ of sterilizations in 40 minutes of 10ml and get final product.
Claims (2)
1. the production system of an XIANGDAN ZHUSHEYE, it is characterized in that: the production system of described XIANGDAN ZHUSHEYE comprises extraction system, dense match system, take off the charcoal system, dilution system, soda acid match system, filtration system and embedding system, wherein extraction system is connecting dense match system, dense match system is connecting the charcoal system taken off, take off the charcoal system and connecting dilution system, dilution system is connecting the soda acid mixing system, and the soda acid mixing system is connecting filtration system, and filtration system is connecting the embedding system.
2. the production system of XIANGDAN ZHUSHEYE according to claim 1, it is characterized in that: described filtration system is comprised of defecator, and defecator is hollow fibre filtering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220587927 CN202920641U (en) | 2012-11-09 | 2012-11-09 | Xiangdan injection production system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220587927 CN202920641U (en) | 2012-11-09 | 2012-11-09 | Xiangdan injection production system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202920641U true CN202920641U (en) | 2013-05-08 |
Family
ID=48210634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220587927 Expired - Fee Related CN202920641U (en) | 2012-11-09 | 2012-11-09 | Xiangdan injection production system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202920641U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027387A (en) * | 2014-07-09 | 2014-09-10 | 湖北天圣康迪制药有限公司 | Method for preparing dalbergia wood distillate |
-
2012
- 2012-11-09 CN CN 201220587927 patent/CN202920641U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027387A (en) * | 2014-07-09 | 2014-09-10 | 湖北天圣康迪制药有限公司 | Method for preparing dalbergia wood distillate |
| CN104027387B (en) * | 2014-07-09 | 2017-06-27 | 湖北天圣药业有限公司 | A kind of preparation method of dalbergia wood distillate |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130508 Termination date: 20131109 |