CN202802188U - Full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device - Google Patents
Full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device Download PDFInfo
- Publication number
- CN202802188U CN202802188U CN201220489515.9U CN201220489515U CN202802188U CN 202802188 U CN202802188 U CN 202802188U CN 201220489515 U CN201220489515 U CN 201220489515U CN 202802188 U CN202802188 U CN 202802188U
- Authority
- CN
- China
- Prior art keywords
- filling
- machine
- conveyer belt
- automatic washing
- arraying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004108 freeze drying Methods 0.000 title claims abstract description 15
- 238000005406 washing Methods 0.000 title claims abstract description 14
- 238000001035 drying Methods 0.000 abstract description 10
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 3
- 230000000712 assembly Effects 0.000 abstract 1
- 238000000429 assembly Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000007710 freezing Methods 0.000 description 4
- 230000008014 freezing Effects 0.000 description 4
- JGSARLDLIJGVTE-UHFFFAOYSA-N 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-UHFFFAOYSA-N 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000005057 refrigeration Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000034189 Sclerosis Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000012792 lyophilization process Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
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- Drying Of Solid Materials (AREA)
Abstract
The utility model provides a full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device which comprises a bottle washing machine, a tunnel drying oven connected with the bottle washing machine, a filling machine connected with the tunnel drying oven, an arraying machine connected with the filling machine, a conveyor belt connected with the arraying machine and a freeze dryer connected with the conveyor belt. According to the full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device, the filling, the freeze-drying and the capping process assemblies pass in and out automatically with needless of manual operation, and therefore production efficiency is improved greatly and possibility of pollution caused by manual operation is avoided.
Description
Technical field
This utility model belongs to the pharmaceutical equipment field, particularly a kind of automatic washing baking filling, permutation and lyophilization interlock pharmaceutical equipment
Background technology
Vacuum lyophilization also claims sublimation drying, is that water-containing materials is freezing to below freezing, makes water change ice into, then changes ice into steam under high vacuum and the drying means removed.Because vacuum lyophilization carries out under low temperature, low pressure, and moisture directly distils, and therefore gives product many special performances.It is more thorough also to dewater to heat sensitive material such as Vacuum Freezing ﹠ Drying Technology, and the medicine of drying is very stable, is convenient to long time stored.Because the drying of material is finished under frozen state, compares with other drying meanss, physical arrangement and the molecule structure change of material are minimum, and its organizational structure and mode of appearance are preserved preferably.In the vacuum lyophilization process, there is not surperficial sclerosis problem in material, and it inner forms the spongy of porous, thereby has excellent rehydration, can recover at short notice the state before dry.Because dry run is to carry out under very low temperature, and has substantially completely cut off air, therefore effectively suppress heat-sensitive substance biology, chemistry or physical change have occured, and preserved preferably the active substance in the raw material, and the color and luster that has kept raw material.
After the Vacuum Freezing ﹠ Drying Technology that freeze dryer originates from the twenties in 19th century has experienced the fluctuating of decades and paces up and down, in last 20 years, make significant progress.Enter 21 century, vacuum freeze drying technology relies on the incomparable advantage of other drying means, more and more is subject to people's favor, especially at pharmaceutical field.
Existing freeze-dried powder agent producing process is: injection bottles made of glass tubes is through pouring into the medicinal liquid after aseptic filtration and partly jump a queue (sterilizing) behind the washing and sterilizing, mode by artificial scraping disc enters in the rustless steel lyophilizing dish glass is bottled, then the lyophilizing dish is put in the go-cart, go-cart is pushed into the vacuum freeze drier pedestrian worker's inlet that advances, and laggard pedestrian worker's outlet is finished in lyophilizing.Therefore, the links of this production technology all needs manually-operated, and one side exists artificial serious interference and produces the risk of microbial contamination, has on the other hand the low problem of production efficiency.
Summary of the invention
The purpose of this utility model is to provide the high automatic washing of a kind of production efficiency to dry by the fire filling, permutation and lyophilization interlock pharmaceutical equipment, and the pollution that can avoid manually-operated to bring.
For achieving the above object, the technical scheme that this utility model adopts is: the dry pharmaceutical equipment of full-automatic refrigeration, comprise bottle washer, the tunnel oven that is connected with bottle washer, the filling machine that is connected with tunnel oven, the lining-up machine that is connected with filling machine, the conveyer belt that is connected with lining-up machine, the freeze dryer that is connected with conveyer belt.
Described freeze dryer and conveyer belt place are provided with the push rod pushing in device.
Described bottle washer, the tunnel oven that is connected with bottle washer, the filling machine that is connected with tunnel oven, the lining-up machine that is connected with filling machine, the conveyer belt that is connected with lining-up machine, the freeze dryer that is connected with conveyer belt all is connected with automatic control system.
Described bottle washer, tunnel oven, filling machine, lining-up machine, conveyer belt and freeze dryer top are provided with A level laminar flow high-efficiency and filter supply air system.Guarantee the cleanliness factor in production space.
This utility model is with fill, permutation, lyophilizing and roll cover process and make up, and material passes in and out automatically, need not manually-operated, has greatly improved production efficiency, and avoids bringing because of manually-operated the probability of microbial contamination.
Description of drawings
Fig. 1 is the structural representation of this utility model automatic washing baking filling, permutation and lyophilization interlock pharmaceutical equipment
The specific embodiment
Make specific descriptions below in conjunction with this this utility model of Figure of description.
As shown in Figure 1: the dry pharmaceutical equipment of full-automatic refrigeration comprises bottle washer 1, the tunnel oven 2 that is connected with bottle washer 1, the filling machine 3 that is connected with tunnel oven 2, the lining-up machine 4 that is connected with filling machine 3, the conveyer belt 5 that is connected with lining-up machine, the freeze dryer 7 that is connected with conveyer belt.Described freeze dryer and conveyer belt place are provided with push rod pushing in device 6.
Described bottle washer 1, tunnel oven 2, filling machine 3, lining-up machine 4, conveyer belt 5, push rod pushing in device 6, freeze dryer equal 7 are connected with automatic control system.
Operation principle is: after bottle washer 1 is cleaned cillin bottle, cillin bottle enters tunnel oven 2 and carries out dry sterilization except the thermal source processing, and after liquid drug was also partly jumped a queue, cillin bottle was after lining-up machine 4 is organized into dish, before conveyer belt 5 is transported to freeze dryer, push freeze drying box 7 through push rod pushing in device 6.
Bottle washer 1, tunnel oven 2, filling machine 3, lining-up machine 4, conveyer belt 5 and freeze dryer 7 tops are provided with A level laminar flow high-efficiency and filter supply air system.
This utility model need not manually-operated and has greatly improved production efficiency, and avoids bringing because of manually-operated the probability of microbial contamination.
Claims (4)
1. automatic washing baking filling, permutation and lyophilization interlock pharmaceutical equipment is characterized in that, comprise bottle washer, the tunnel oven that is connected with bottle washer, the filling machine that is connected with tunnel oven, the lining-up machine that is connected with filling machine, the conveyer belt that is connected with lining-up machine, the freeze dryer that is connected with conveyer belt.
2. automatic washing baking filling as claimed in claim 1, permutation and lyophilization interlock pharmaceutical equipment is characterized in that described freeze dryer and conveyer belt place are provided with the push rod pushing in device.
3. automatic washing as claimed in claim 1 dries by the fire filling, permutation and lyophilization interlock pharmaceutical equipment, it is characterized in that, described bottle washer, the tunnel oven that is connected with bottle washer, the filling machine that is connected with tunnel oven, the lining-up machine that is connected with filling machine, the conveyer belt that is connected with lining-up machine, the freeze dryer that is connected with conveyer belt all is connected with automatic control system.
4. such as one of claim 1-3 described automatic washing baking filling, permutation and lyophilization interlock pharmaceutical equipment, it is characterized in that described bottle washer, tunnel oven, filling machine, lining-up machine, conveyer belt and freeze dryer top are provided with A level laminar flow high-efficiency and filter supply air system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220489515.9U CN202802188U (en) | 2012-09-20 | 2012-09-20 | Full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220489515.9U CN202802188U (en) | 2012-09-20 | 2012-09-20 | Full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202802188U true CN202802188U (en) | 2013-03-20 |
Family
ID=47861136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201220489515.9U Expired - Lifetime CN202802188U (en) | 2012-09-20 | 2012-09-20 | Full-automatic washing and baking and filling and arraying and freeze drying linkage pharmaceutical device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202802188U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103332641A (en) * | 2013-07-15 | 2013-10-02 | 江阴双特机械设备有限公司 | Volumetric servo filling production line |
| CN103690367A (en) * | 2013-12-23 | 2014-04-02 | 广西南宁百会药业集团有限公司 | Full-automatic freeze drying pharmaceutical equipment |
-
2012
- 2012-09-20 CN CN201220489515.9U patent/CN202802188U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103332641A (en) * | 2013-07-15 | 2013-10-02 | 江阴双特机械设备有限公司 | Volumetric servo filling production line |
| CN103332641B (en) * | 2013-07-15 | 2015-05-06 | 江阴双特机械设备有限公司 | Volumetric servo filling production line |
| CN103690367A (en) * | 2013-12-23 | 2014-04-02 | 广西南宁百会药业集团有限公司 | Full-automatic freeze drying pharmaceutical equipment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 310018 No.1 street, Hangzhou Economic and Technological Development Zone, Zhejiang Province Patentee after: Hangzhou AoYa Biotechnology Co.,Ltd. Address before: 310012 No.1 street, Hangzhou Economic and Technological Development Zone, Hangzhou City, Zhejiang Province Patentee before: HANGZHOU AUSIA BIOLOGICAL TECHNOLOGY Co.,Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130320 |