[go: up one dir, main page]

CN202314939U - Easy painless medicine infusing device - Google Patents

Easy painless medicine infusing device Download PDF

Info

Publication number
CN202314939U
CN202314939U CN2010205986160U CN201020598616U CN202314939U CN 202314939 U CN202314939 U CN 202314939U CN 2010205986160 U CN2010205986160 U CN 2010205986160U CN 201020598616 U CN201020598616 U CN 201020598616U CN 202314939 U CN202314939 U CN 202314939U
Authority
CN
China
Prior art keywords
micropin
loading
drug administration
medicine
painless
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2010205986160U
Other languages
Chinese (zh)
Inventor
张晓安
张晶莹
李敏杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jilin University
Original Assignee
Jilin University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jilin University filed Critical Jilin University
Priority to CN2010205986160U priority Critical patent/CN202314939U/en
Application granted granted Critical
Publication of CN202314939U publication Critical patent/CN202314939U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Landscapes

  • Media Introduction/Drainage Providing Device (AREA)

Abstract

本实用新型涉及一种方便使用、经济实惠、适用于长期给药的轻松无痛输药装置,属于医疗技术领域。该输药装置的特征在于:装置含有隐藏式的弹性微针,能够在瞬时透皮给药后自动缩回,既保证无痛、高效给药,又避免了原有微针输药技术采用的长时间皮下埋针引发的皮肤过敏发炎等问题;装置内至少含一个独立输药单元,该独立输药单元采用待施的固体药物和驱动液安全分储,只是在输药的瞬间将其混合溶解,并通过微针注入皮下。这种固液分储、即溶即输的新模式,解决了某些药物溶液室温下不易储存、需要冷藏等技术瓶颈;装置通过手动或使用外接的可反复使用的电子自动施压控制施药,大大降低装置的制造成本和广大普通患者的消费负担;装置具有优良的防湿、透汗、防压等功能,使用更加舒适、安全;装置既可以长期佩戴,也可以根据需要随用随带,定量皮下给药,灵活便用。该装置适用于需要长期定时透皮给药的患者,例如糖尿病患者的胰岛素给药。

The utility model relates to an easy-to-use and painless medicine transfusion device which is convenient to use, economical and practical, and suitable for long-term administration, and belongs to the field of medical technology. The feature of the drug infusion device is that the device contains hidden elastic microneedles, which can be automatically retracted after instantaneous transdermal drug delivery, which not only ensures painless and efficient drug delivery, but also avoids the problems of the original microneedle drug delivery technology. Problems such as skin allergies and inflammations caused by long-term subcutaneous needle embedding; the device contains at least one independent drug infusion unit, which uses the solid drug to be administered and the driving fluid to be safely separated and stored, and is only mixed at the moment of drug infusion Dissolved and injected subcutaneously via a microneedle. This new mode of solid-liquid storage and instant dissolving and transfusion solves technical bottlenecks such as the difficulty of storing certain drug solutions at room temperature and the need for refrigeration; the device controls drug application manually or by using an external reusable electronic automatic pressure application , which greatly reduces the manufacturing cost of the device and the consumption burden of ordinary patients; the device has excellent functions such as moisture-proof, sweat-permeable, and pressure-resistant, making it more comfortable and safe to use; the device can be worn for a long time, or it can be taken with you as needed Subcutaneous administration, flexible and convenient to use. The device is suitable for patients who need long-term timed transdermal administration, such as insulin administration for diabetic patients.

Description

Light painless drug administration device
Technical field
The invention belongs to field of medical technology, relate to a kind of light painless drug administration device, can help the patient that need have an injection for a long time to reduce or remit pain.
Background technology
Diabetes are human body physiological function disorder diseases that the present whole world can't cure; It not only has a strong impact on patient's orthobiosis; Also can cause 80 various acute or chronic complicating diseases such as comprising the heart, brain, liver, lung, kidney, eye, limbs, skin, nerve simultaneously; Cause that the patient is blind, loss of memory, cerebral palsy, gingiva and skin of lower extremity festers, lower limb nerve necrosis, paralysis, sexual disorder and forfeiture, glomerular sclerosis, arteriosclerosis heart disease, and even serious consequence such as death.Current research shows, such sick global patient reaches several hundred millionly at present, and only this type of patient of China just surpasses more than 9,200 ten thousand, and patient's quantity also increases sharply in the speed with annual more than 150 ten thousand.Helping this type patient to keep the best approach of orthobiosis at present is exactly usually to control patient's blood glucose with islets of langerhans.Yet; Insulin is a kind of polypeptide drug; Be easy to by human intestines and stomach's digestive enzyme degraded with because of the first pass effect inactivation of liver; Replenishing of this type of patient medicine can only lean on the vein of every day or subcutaneous injection to realize, this not only brings pain of local skin damage, infection and secular skin and flesh that injection causes to the patient, and it is inconvenient also to have increased a lot of lives simultaneously.How helping the patient to alleviate the administration misery is the focus that the medical science and technology worker endeavours to solve.
The quick insulin syringe that various types of single or multiples use is arisen at the historic moment, and the use of this appliances not only brings suffering of flesh to the patient, and expense is high simultaneously, and waste is big.People also once attempted insulin is processed plaster, attempt to realize administration through the mode of Transdermal absorption, yet because insulin molecule is huge, it were also lower to infiltrate intravital efficient through the human epidermal cutin membrane.
The solution of rising in recent years is to adopt the micropin dispenser to overcome pain of skin and flesh that injection brings, and insulin can't be through problems such as epidermis infiltrate in the body.Although the patent application of micropin dispenser aspect is a lot, most processing that all belong to dissimilar micropins are oozed the medicine application with simple transdermal, have only minority that more complete feasible micropin pesticide application technology is provided.Present micropin pesticide application technology can roughly be divided into Wicresoft's transdermal and ooze two types of medicine and imbedding needle dispensers, and the former is through the perforation of micropin transdermal, impel be coated on the micropin surface or the medicinal liquid on the plaster through micropore to subcutaneous infiltration; Because the defence and the self-repair function of human body skin; Make the Wicresoft of cutin membrane heal rapidly; This can effectively stop the intrusion of external microbe on the one hand, but also hinders macromolecular drug to pass through the subcutaneous dispenser of Wicresoft's passage on the other hand, therefore; This type Wicresoft transdermal oozes the medicine method and exists the curative effect weak point, oozes problems such as medicine is incomplete, drug waste is big.For the latter; It mostly is the micropin that includes medicinal liquid or communicate through imbedding with medicine bag; Through the micropin passage; To the subcutaneous medicine that oozes, although do not receive the puzzlement of cutin membrane minimal invasion healing problem, this type system exists subcutaneous tissue to the anaphylaxis of imbedding micropin with ooze problems such as medicine speed is slow, administration is inhomogeneous.
Recently the microelectronics that emerges controls intelligent loading technology; Adopt microelectronics control and the integrated drug-supplying system of micropin loading assembly, have small and exquisite, convenient, administration on time, administration such as gives at advantage as required, solved that curative effect is short, administration is uneven and ooze medicine waits problem slowly; But still exist subcutaneous tissue to imbedding the allergic problem of micropin for a long time; In addition because microelectronics loading control assembly complex design that system adopted, production cost are high, and be to use up and finish mission, not only cause a lot of wastes and pollution problem with the medicine in this plaster; Increase simultaneously the cost of manufacture and the cost of use of plaster again greatly, make vast ordinary consumer forbidding.In addition, this type drug administration device this bring a lot of inconvenience for patient's daily routines undoubtedly.
In addition, it is pointed out that almost the subcutaneous loading method of all insulins on the market; Comprise micropin loading technology; All adopt insulin solutions, because insulin in unstable, the easy degraded of solution state, not only needs strict aseptic anoxybiotic encapsulation; Also necessary simultaneously cryopreservation, this has brought very big restriction for undoubtedly micropin plaster long-time demand of using under the body temperature environment.
Therefore, be badly in need of a kind of inexpensive, painless convenience, long-acting, demand that loading system that efficiently do not have skin allergy again satisfies extensive patients at present.
Summary of the invention
The present invention relates to a kind of light painless drug administration device, this device is made up of one or more independently loadings unit, contains concealed micropin in each loading unit, when needing, through exerting pressure, makes withdrawal automatically behind the instantaneous transdermal administration of micropin, realizes painless administration.This drug administration device has simple in structure, and cost of manufacture is low, and safety and comfort are ventilative moistureproof, can painless efficient administration, do not cause the skin allergy inflammation again, and both can paste usefulness for a long time, advantages such as also can putting at any time and take off, flexible, economical and practical.
The present invention is achieved in that
At least contain an independent loading unit in this drug administration device, the loading list includes concealed micropin and drug storage chamber.In drug storage chamber, solid drugs and loading drive liquid to be separated by stable barrier film, and the design that this solid drugs and loading driving liquid are stored has respectively promoted long-term drug storage property under stability and the room temperature of insulin greatly.In the moment of loading, the barrier film opening allows the rapid mixed dissolution of solid-liquid, and subcutaneous through the micropin injection, and this long-term branch storage, instant promptly defeated new model have solved technical bottlenecks such as being difficult for storing, needing cold preservation under the insulin medicinal liquid room temperature.
Micropin is connected with elastomeric material, makes elastomeric material deformation through pressure, drives microneedle cutaneously, removes withdrawal automatically behind the pressure, isolates with epidermis.Both guaranteed painless, efficient administration, the problems such as skin allergy inflammation that the long-time needle-embedding therapy of having avoided original micropin loading technology to adopt again causes.
This device is through adopting manually or using external repeatedly used microelectronics to exert pressure automatically and control loading unit dispenser; Replace existing disposable integrated micro loading control system, reduce the manufacturing cost of device and the consumption burden of vast general patient greatly.
Functions such as that the design of this drug administration device has simultaneously added is damp proof, have a good sweat, anti-pressure make that the use of this device is more comfortable, safety.
Advantage of the present invention is:
(1) drug administration device can be realized that the long course of treatment is painless, efficient, make things convenient for administration.
(2) economical and practical, the convenient use both can the long periods of wear dosed administration, also can be as required with going along with.
(3) be not only applicable to the insulin administration of diabetics, be applicable to other type medicine simultaneously yet, replenish the long-term timing transdermal administration of contraception, smoking cessation and beauty and skin care etc. as human body is hormonal.
Description of drawings
Fig. 1 is the partial cross section figure of the micropin loading parts (100) of light painless drug administration device.Wherein, 101 signal medicine outputs drive liquid; 102 signal medicines drive the outer enclosure material of liquid; 103 signals drive the isolated thin film of liquid with solid drugs and medicine output; The solid drugs of output is waited in 104 signals; The thin-film material that 105 signals link to each other with micropin; 106 signals are used for the micropin of transdermal infusion; The micropin part that 107 signals will be equipped with solid drugs joins material with the glue that the loading control system that driving liquid is housed is connected; 108 signals are used to carry the thin slice that micropin, medicine and encapsulating material are connected.It is pointed out that in actual design 108 can be similar or the inhomogeneity material with 105 or 107, when 108 and 105 or 107 same time-likes, it can dispense from these parts (100) structure.
Fig. 2: divide upper, middle and lower figure, the micropin that wherein upper and lower figure is light painless drug administration device is hidden the partial cross section figure of seal member (110) diverse location, the parts of fine web frame in these parts of middle illustrated.Wherein: 111 signals are used for the thin film of sealed damp-proof; The hidden micropin of 112 signals, avoid the rigid support grid of micropin and contact skin; 113 signals have certain tensile elasticity, are used for supporting the filamentary webs of micropin.It is pointed out that 113 are not limited to resilient filament guard, it also can be other resilient thin film or thin slice.
Fig. 3: the partial cross section figure of light painless drug administration device, wherein: 120 signals are used to prevent that the loading control system receives unconscious extruding and leaks the pressure support material of medicine; Other digital signal is said with Fig. 1 and Fig. 2.
Fig. 4: the schematic top plan view of the loading safety block (120) of light painless drug administration device, these parts are used to prevent that the loading control system receives unconscious extruding and leaks medicine.
Fig. 5: be used for drug administration device and the fixed optional feature of skin (130) schematic top plan view, be breathe freely by having well, have a good sweat, thin slice such as the natural or TPR of heat radiation, bio-compatibility and fabric or leather, plastics, paper makes; This thin slice can be that single face scribbles adhesive, drug administration device is bonded in skin surface, but also is not coated with any adhesive, can make above-mentioned material system that device and body part closely contact through any external force.
Fig. 6: the schematic top plan view of the micropin loading parts (100) of light painless drug administration device.Wherein 101 and 102 signal is said with Fig. 1.
Fig. 7: the schematic top plan view of light painless drug administration device, wherein all digital signals are the same.
Fig. 8: the micropin of light painless drug administration device is hidden with the end of seal member and is looked sketch map.Wherein each digital signal is said with Fig. 2.
Fig. 9: the bottom view of light painless drug administration device, wherein each digital signal is with the above.
The specific embodiment
The present invention is a kind of light painless drug administration device that can behind instantaneous transdermal administration, withdraw automatically; This device includes an independent loading unit at least, and each at least one length of independent loading unit and diameter be basically all at the micropin of micrometer range, under some special situation that needs usefulness; The yardstick of micropin sometimes can near or greater than one millimeter; This micropin links to each other with the unitary drug storage chamber of this loading, and solid drugs in micropin and/or the drug storage chamber and loading drive liquid to be separated by stable barrier film, when the moment at loading; When the independent control action that manual or external repeatedly used microelectronics is exerted pressure automatically; The barrier film opening allows the solid-liquid mixed dissolution, and injects subcutaneous through micropin.This device both can be used for long-term subcutaneous dosed administration, also can need not take off as required with going along with, have flexibly just use, easily painless, efficient administration, advantage such as economical and practical.Following description and the diagram that provides only are in order to let the reader of common level can understand and put into practice the principles of science of present patent application and the schematic part illustration that characteristics provide; But be not that our invention of limitation is in this; Varied drug administration device design of any the principles of science that provides based on patent specification and products characteristics all belongs in this invention patent protection category like the mode of the layout of the stressed mode of size, thickness, the quantity that includes the unitary quantity of independent loading and shape, micropin and length, the structure of drug storage nest, loading, used material, safety block and shape, enhancement micropin loading unitary elasticity etc.
Shown in sketch map 1-9, this type device mainly is to be made up of following three assemblies: micropin loading parts (100); Micropin is hidden seal member (110); The safety block of loading control system (120).
The parts of micropin loading (100) are the core components of this drug administration device; Undertaking safety and dividing storage medicine to be executed and drive liquid, and the independent loading unit of opening, each loading unit load has the medicine of various dose; During loading, will drive liquid and medicine and mix rapidly and inject functions such as subcutaneous.Micropin loading parts (100) are made up of 8 parts: 1. medicine output drives liquid (101); 2. medicine drives the outer enclosure material (102) of liquid; 3. solid drugs and medicine output are driven the isolated thin film of liquid (103); 4. wait for the solid drugs (104) of output; 5. the thin-film material that links to each other with micropin (105); 6. the micropin (106) that is used for transdermal infusion; The micropin part that 7. solid drugs will be housed joins material (107) with the glue that the loading control system that driving liquid is housed is connected; 8. be used to carry micropin and medicine thereof and the thin slice (108) that is connected with the encapsulating material that the loading control system that drives liquid is housed.Wherein (108) can with (105) or (107) the similar or inhomogeneity material in the same parts (100).When (108) and (105) or (107) same type of material, it can dispense from this (100) modular construction.
Wherein encapsulating material (102) can be metal or high-molecular organic material, comprises artificial or biological or natural material.
The solid-liquid isolating membrane (103) that here uses can be organic molecule, organic polymer or biomaterial.Be characterized in: under normal pressure, have good seal, can intercept loading driving liquid effectively and permeate, but, can allow liquid to pass through barrier film through modes such as film breaks or film micropore increases when receiving under the ambient pressure effect to solid drugs.
The solid drugs (104) of waiting for output here can be an insulin, also can be that other classes are applicable to hypodermic medicine.
The thin-film material that here links to each other with micropin (105) can be prepared by metal level or alloy, also can be by inorganic material, and high-molecular organic material, organic-inorganic hybrid material is mixed with.
The micropin (106) that is used for transdermal infusion here can also can be mixed with by inorganic material, high-molecular organic material, organic-inorganic hybrid material by the thin-film material that is attached thereto (105) identical or different metal level or alloy preparation.
It can be synthetical or natural macromolecular material that glue joins material (107); Like epoxy resin, silica type, animal glue class, polyester, polyamide etc., also can be to receive ambient light, heat, water or chemical reagent to stimulate the chemical monomer that cross-linked polymeric takes place down to prepare.
Being used to carry micropin and medicine thereof with the thin slice (108) that is connected with the encapsulating material that the loading control system that drives liquid is housed can be and similar or inhomogeneous metal of encapsulating material (102) or high-molecular organic material.
Micropin is hidden seal member (110) and is supported hard grid (112) and elastic force guard or thin film or thin slice (113) and forms by sealing film (111), micropin, is to be used to control instantaneous transdermal infusion in this drug administration device and to prevent the important accessory of skin to the infection of this device allergy.It is being undertaken under non-loading situation and to hide micropin, avoids micropin to contact for a long time with skin and causes anaphylactic reaction; Encapsulate each loading unit, guarantee to treat that the loading thing does not receive the influence and the deliquescence of human body sweat gland secretion thing and moisture; For independent loading unit the elasticity support is provided simultaneously; Make it when loading; Micropin head in this separate unit can sting unitary seal film and the administration of skin surface cutin membrane rapidly; And micropin is rebounded automatically after dispenser, hightails skin, avoids micropin to imbed for a long time and causes the skin allergy inflammation in the body.
Wherein sealing film (111) is to place micropin to support hard grid (112) and elastic force guard or thin film or thin slice (113) biofilms single-ended or two ends up and down or thin synthetic film.It can effectively stop human body sweat gland secretion thing, moisture and oxygen to invade in the micropin loading system, guarantees that the long-term stability of treating the dispenser thing stores; Seal film strength and thickness the leaning out of micropin when not influencing administration, and have good bio-compatibility, do not cause allergic reaction when contacting for a long time with skin.
The micropin here support hard grid (112) be one type by organic or inorganic or hybrid material preparation, highly be slightly larger than the rigid support structure of the arbitrary shape of micropin length.It is characterized in that: can with seal film (111) and elastic force guard or thin film or thin slice (113) constitutes the structure of independent closed hollow unit one by one---the hidden nest of micropin.The shape of single hidden nest can be circle, ellipse, N limit shape (N>3) or other Any shape.Here the inorganic material of indication comprises metal and nonmetal, and the hybrid material of indication is organic and inorganic hybrid material.
Elastic force guard here or thin film or thin slice (113) be place micropin support hard grid (112) single-ended or up and down two ends, seal the film inboard silk screen with tensile elasticity, thin film or thin slice; Can the elasticity support be provided for each the independent loading unit in the drug administration device; Its micropin can be shot out when loading, draw back rapidly after the dispenser.This type elastic force silk screen, thin film or thin slice can be by natural silks; Like silkworm silk, spider silk etc., rubber, Plant fiber, synthetic fibers, metal or metal alloy preparation; Its thickness and elastic strength are different because of need; Should guarantee the no medicine leakage before the transdermal cutin membrane of the unitary pastille micropin of this loading, can help micropin behind loading, to draw back from epidermis automatically again simultaneously.
The safety block of loading control system (120) is to place the drug administration device top, surround that independent loading is unitary, the adnexa of netted or array structure with withstand voltage properties.It is equal to or is higher than the unitary top of loading highly at least, is used to protect the loading unit because of receiving unexpected extruding drug leakage to take place.The manufacturing materials of these parts can be a metal or nonmetal, and also organic polymer or inorganic material can also be organic and inorganic hybrid materials.These parts also can add one have an elastic force puller strap bucker, do not intake to guarantee patient's its drug administration device of being worn when the bathing.
This device also can have an adnexa (130) as required, and adnexa (130) can be used for drug administration device is fixed on the skin.
Be used for drug administration device is fixed on the optional feature (130) on the skin.It is characterized in that: these parts be breathe freely by having well, have a good sweat, thin slice such as the natural or TPR of heat radiation, bio-compatibility and fabric or leather, plastics, paper makes.This thin slice can be that single face scribbles adhesive; Can the loading device be bonded in skin surface; But be not coated with any adhesive yet, can be through any external force, like bandage, vac sorb, manually push etc.; Make above-mentioned material system that device and body part closely contact, guarantee the comfort level that the patient uses.
Light painless drug administration device is placed in the position of physical comfort, when needs, through manual or external exerting pressure automatically; As push, control such as extruding, with the unitary medicine of one or more loadings, through the administration of micropin thorn transdermal; When loosing one's grip; Or behind the automatic control order fulfillment, used loading unit micropin rebounds automatically, isolates with skin.Meanwhile, micropin in the untapped loading of other on the plaster unit and loading system thereof still are in solid-liquid and divide storage, the sealing state of hiding, get ready for a journey, and can launch one by one, life-time service.It is pointed out that the external control system of exerting pressure automatically of indication here, can be any feasible devices such as electronics, microelectronics, machinery.
In fact; When light painless drug administration device of the present invention combines with the external repeatedly used control system of exerting pressure automatically; Timing or administration had as required both been realized; The micropin that solves the intelligent loading system of existing microelectronics control is imbedded problems such as subcutaneous initiation allergy for a long time, greatly reduces the patient economy burden of accepting automatic loading treatment simultaneously again.

Claims (11)

1. a light painless drug administration device is characterized in that containing at least one independent loading unit, exerts pressure through manual or external device and controls one or more independent loadings unit loading as required, and the elasticity micropin is withdrawn automatically behind the loading.
2. light painless drug administration device according to claim 1 is characterized in that by micropin loading parts (100), micropin is hidden seal member (110), and the safety block of loading control system (120) constitutes.
3. light painless drug administration device according to claim 2 is characterized in that described micropin loading parts (100) are made up of 8 parts, comprises that 1. medicine output drives liquid (101); 2. medicine drives the outer enclosure material (102) of liquid; 3. solid drugs and medicine output are driven the isolated thin film of liquid (103); 4. wait for the solid drugs (104) of output; 5. the thin-film material that links to each other with micropin (105); 6. the micropin (106) that is used for transdermal infusion; 7. micropin is joined material (107) with the glue that the loading control system that medicine and driving liquid are housed is connected; 8. be used to carry micropin and medicine thereof and the thin slice (108) that is connected with the encapsulating material that the loading control system that drives liquid is housed.
4. according to claim 2 or 3 described light painless drug administration devices; It is characterized in that, being used in the described micropin loading parts (100) carry micropin, medicine and the thin slice that is connected with encapsulating material (108) can be with encapsulating material (102), the thin-film material (105) that links to each other with micropin or with micropin with medicine is housed and drives glue couplet similar or inhomogeneous metal of material (107) or the high-molecular organic material that the loading control system of liquid is connected; Join material (107) when being same type of material with the thin-film material (105) that links to each other with micropin or with micropin with the glue that the loading control system that medicine and driving liquid are housed is connected when carrying micropin, medicine and the thin slice that is connected with encapsulating material (108), it can dispense from this (100) modular construction.
5. light painless drug administration device according to claim 2 is characterized in that, described micropin is hidden seal member (110) and formed by sealing film (111), micropin support hard grid (112) and elasticated net or thin film or thin slice (113) three parts.
6. according to claim 2 or 5 described light painless drug administration devices, it is characterized in that described micropin is hidden seal member (110), sealing film (111) can be biomembrane material or the thin synthetic film with bio-compatibility; It is the rigid support structure that highly is slightly larger than the arbitrary shape of micropin length that micropin supports hard grid (112).
7. according to claim 2 or 5 described light painless drug administration devices; It is characterized in that; Elasticated net, thin film or thin slice (113) that described micropin is hidden in the seal member (110) are prepared by natural silk, rubber, Plant fiber, synthetic fibers, metal or metal alloy; Place micropin support an end of hard grid or up and down two ends, seal silk screen, thin film or thin slice that the film inboard has tensile elasticity; This elasticated net, thin film or thin slice can provide the elasticity support for each the independent loading unit in the drug administration device, and its micropin can be shot out when loading, draw back rapidly after the dispenser.
8. light painless drug administration device according to claim 2; It is characterized in that; The safety block of described loading control system (120) places the drug administration device top and around around the independent loading unit; Highly be equal to or be higher than top, loading unit, have the adnexa of the netted or array structure of withstand voltage properties.
9. light painless drug administration device according to claim 2 is characterized in that, the safety block of described loading control system (120) is that these parts also can add a bucker that has the elastic force puller strap as required.
10. light painless drug administration device according to claim 1 is characterized in that this device also can have one to be used for device is fixed on the optional feature (130) on the skin as required.
11. light painless drug administration device according to claim 10; It is characterized in that; Described drug administration device is fixed on the optional feature (130) on the skin, be breathe freely by having well, have a good sweat, thin slice such as the natural or TPR of heat radiation, bio-compatibility and fabric or leather, plastics, paper makes; This thin slice can be that single face scribbles adhesive, can drug administration device be bonded in skin surface, but also not be coated with any adhesive, can make above-mentioned material system that device and body part closely contact through any external force.
CN2010205986160U 2010-11-10 2010-11-10 Easy painless medicine infusing device Expired - Fee Related CN202314939U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010205986160U CN202314939U (en) 2010-11-10 2010-11-10 Easy painless medicine infusing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010205986160U CN202314939U (en) 2010-11-10 2010-11-10 Easy painless medicine infusing device

Publications (1)

Publication Number Publication Date
CN202314939U true CN202314939U (en) 2012-07-11

Family

ID=46426944

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010205986160U Expired - Fee Related CN202314939U (en) 2010-11-10 2010-11-10 Easy painless medicine infusing device

Country Status (1)

Country Link
CN (1) CN202314939U (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104043192A (en) * 2014-06-28 2014-09-17 陈彦彪 Disposable microneedle device
CN105963855A (en) * 2016-06-22 2016-09-28 成都市亿泰科技有限公司 Microneedle drug delivery patch containing separable drug capsule
CN112969495A (en) * 2018-10-31 2021-06-15 富士胶片株式会社 Microneedle array unit

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104043192A (en) * 2014-06-28 2014-09-17 陈彦彪 Disposable microneedle device
CN105963855A (en) * 2016-06-22 2016-09-28 成都市亿泰科技有限公司 Microneedle drug delivery patch containing separable drug capsule
CN112969495A (en) * 2018-10-31 2021-06-15 富士胶片株式会社 Microneedle array unit
CN112969495B (en) * 2018-10-31 2022-11-08 富士胶片株式会社 Microneedle array unit

Similar Documents

Publication Publication Date Title
Zhang et al. Advances in transdermal insulin delivery
US11744937B2 (en) Flexible and conformal patch pump
CN102657914B (en) Micro-needle transdermal delivery patch with high penetration efficiency
US8206336B2 (en) Methods for reducing pain using a transdermal local anesthetic patch with injection port in combination with an electromotive force
WO1991008783A1 (en) Implantable device for administration of drugs or other liquid solutions
GB2459101A (en) Subcutaneous port and catheter
CN105963855A (en) Microneedle drug delivery patch containing separable drug capsule
EP2482915A2 (en) Device and method for drug delivery to a targeted skin layer
CN202314939U (en) Easy painless medicine infusing device
CN101972499A (en) Easy painless drug delivery device
US8349358B1 (en) Transdermal anesthetic applicator having thermochromic indication
WO2018133786A1 (en) Portable transdermal administration patch apparatus and preparation method thereof
CN208611492U (en) Indwelling needle for insulin injection
CN205163823U (en) Paste type that declines hypodermic device
CN105477746A (en) Miniature adhesive subcutaneous injection device
CN207412507U (en) A kind of ultra-fine transdermal micro needle
CN104645459A (en) Insulin injector
CN117836022A (en) Drug delivery device with cannula with bioactive agent
CN114768075A (en) Sealing paste
Kim et al. Implantable device with magnetically rotating disk for needle‐free administrations of emergency drug
CN205867230U (en) Hypodermic structure
CN204364550U (en) A kind of ankle infusion device
CN202105267U (en) Medical disposable hypodermic injection needle
RU185720U1 (en) The cutaneous device of the system for repeated subcutaneous administration of a drug solution
CN203139282U (en) Novel drug injection auxiliary device

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120711

Termination date: 20161110

CF01 Termination of patent right due to non-payment of annual fee