CN202184823U - Microporous absorbable coronary stent - Google Patents
Microporous absorbable coronary stent Download PDFInfo
- Publication number
- CN202184823U CN202184823U CN 201120163828 CN201120163828U CN202184823U CN 202184823 U CN202184823 U CN 202184823U CN 201120163828 CN201120163828 CN 201120163828 CN 201120163828 U CN201120163828 U CN 201120163828U CN 202184823 U CN202184823 U CN 202184823U
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- micropore
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- body member
- absorb support
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Abstract
The utility model belongs to the technical field of the medical material and specifically relates to micropore coronary artery can absorb support. The microporous coronary absorbable stent comprises stent main body members and connecting rods, wherein adjacent stent main body members are connected through the connecting rods. The utility model provides a micropore coronary absorbable stent which has simple structure, good implantation effect, increased drug carrying capacity and prolonged drug action time.
Description
Technical field
This utility model relates to the medical material field, and specifically micropore ACS can absorb support.
Background technology
The arteria coronaria interventional therapy develops into today; Having experienced coronary artery balloon expandable (PTCA), arteria coronaria is implanted into bare bracket (BMS) and arteria coronaria interplantation and is used as medicine and is coated with three epoch of support (DES); Restenosis rate drops to 20%～30% of the BMS epoch by 30%～50% in the blood vessel; And below 10% of DES epoch, explain that DES has certain curative effect aspect the solution neointimal hyperplasia problem.
The problem that DES possibly cause the later stage thrombus takes place in recent years; Further develop coating degradable medicaments slowly-releasing coronary artery bracket, hope to eliminate the thrombus problem that coating causes, these supports all are nonvolatil being implanted in the blood vessel; Long-term pathology shows possibly cause adverse consequences; For example support fracture hinders X-ray according to shadow, and increases once more the operation easier of implant frame.
The Wholly-degradable support is an emerging product, and therefore market expansion very high speed is described as the 4th revolution of operation on vessels of heart.Biodegradable stent has solved the metal medicine and has been coated with the caused thrombosis problem in support implantation back first; Second be because the significantly improvement of degradation material technology; Improved bio-compatibility; Before not upgrading better chd prevention medicine appearance, biodegradable stent will inevitably be the main flow of intravascular stent in future.The design concept of Wholly-degradable support is just causing people's extensive interest at present.Ability controlled, the persistence drug release that this support need have, and have enough mechanical support power to avoid the negativity reconstruct of blood vessel, also can be noinvasive coronary angiography (MRI and CT) in addition and discern.Theoretically, in a single day this support absorbs fully, i.e. the residual body of the support of noresidue, local vascular can obtain repairing; Therefore this support does not have potential harmful effect to the arteria coronaria blood vessel.Like this, the late period/generation of utmost point stent thrombosis in late period should reduce, so need not secular antiplatelet drug treatment.In addition, because support can be absorbed, so the easypro motion of contracting of local vascular is able to recover, and do not increase once more the operating difficulty of PCI or surgery myocardial revascularization.
The utility model content
But this utility model provide a kind of simple in structure, implant effective, as the to increase support medicine amount of carrying, and the micropore ACS of prolong drug action time can absorb support.
This utility model is realized through following technical proposals:
Micropore ACS can absorb support; Comprise rack body member and connecting rod; The adjacent stent main component is connected through connecting rod, said rack body member with or connecting rod be provided with at least one micropore, said rack body member is pure magnesium or magnesium alloy or polymer.
Said rack body member is the regular serpentine rings that arc section links to each other and forms with snakelike section, and said connecting rod is uniformly distributed with the arc section wave crest place that is connected in the adjacent stent main component at interval, and said micropore is located on snakelike section.
Said rack body member outside is provided with medication coat, and said micropore contains visible development enhancing substance under medicine or the development of X line or MRI, the CT.
Said micropore rounded or square or triangle or ellipse or flute profile.
Said micropore is through hole or blind hole.
Said micropore adopts linear array or non-rectilinear to arrange.
Said polymer is polylactic acid, polyglycolic acid, gather at least a in anhydride and the copolymer thereof.
Said polymer is at least a in caprolactone modification polymer, Polyethylene Glycol, hydrogel, photocuring hydrogel, the terminal diol, derivatives.
Said polymer is at least a in polysaccharide, protein, polyester, PHA, polyamide, polycaprolactone, polyester, polyesteramide, polyvinyl alcohol, propylene glycol carbonic acid, the polyacrylate.
Said magnesium alloy is magnalium or magnesium-zinc alloy.
The beneficial effect that this utility model brought is:
In this utility model, said micropore ACS can absorb support and comprise rack body member and connecting rod, and the adjacent stent main component is connected through connecting rod, and this kind compound mode makes support have certain supportive and contractility; Said rack body member with or connecting rod be provided with at least one micropore; Said micropore has increased the surface area of support, can increase the medicine amount of carrying, and reduces the thickness of support; Increase the internal diameter of support; And micropore can be used for visible development enhancing substance under storage of pharmaceutical or the development of X line or MRI, the CT, and the material in the micropore is difficult for by the blood erosion or by the blood vessel wall abrasion, and then has prolonged drug treating time.
Description of drawings
Below in conjunction with accompanying drawing this utility model is done further explain.
Fig. 1 launches sketch map for the planar structure that the said micropore ACS of this utility model can absorb support;
Fig. 2 is the partial enlarged drawing at A place among Fig. 1;
Fig. 3 is the profile at B-B place among Fig. 1.
The label that component names is corresponding among the figure is following:
1, rack body member; 11, arc section; 12, snakelike section; 2, connecting rod; 3, through hole; 4, medication coat.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment this utility model is done further to detail:
Can absorb the embodiment of support as the said micropore ACS of this utility model; Like Fig. 1, Fig. 2 and shown in Figure 3; Comprise rack body member 1 and connecting rod 2, adjacent stent main component 1 is connected through connecting rod 2, and said rack body member 1 is provided with three micropores; Said micropore is a through hole 3, and said rack body member 1 is a magnesium alloy.This kind compound mode makes support have certain supportive and contractility; Said through hole 3 has increased the surface area of support, can increase the medicine amount of carrying, and reduces the thickness of support, increases the internal diameter of support.
In the present embodiment, the regular serpentine rings that said rack body member 1 links to each other and forms with snakelike section 12 for arc section 11, said connecting rod 2 is uniformly distributed with the arc section 11 wave crest places that are connected in adjacent stent main component 1 at interval, and said through hole 3 is located on snakelike section 12.
In the present embodiment, said rack body member 1 outside is provided with medication coat 4, and said through hole 3 contains medicine.Said through hole 3 can be used for storage of pharmaceutical, and the medicine in the through hole 3 is difficult for by the blood erosion or by the blood vessel wall abrasion, and then has prolonged drug treating time.
In the present embodiment, said through hole 3 is rounded, and adopts linear array.
Certainly, also can be provided with on micropore or rack body member and the connecting rod on the said connecting rod micropore is set simultaneously; Said support also can or be opened support or laser cut stent or injection molding support or helical mount for noncontinuity ring support or continuous circular shape support or closed supports; Also can contain visible development enhancing substance under development of X line or MRI, the CT in the said micropore; Said micropore also can be square or triangle or ellipse or flute profile; Said micropore also can be blind hole; Said micropore also can adopt non-rectilinear to arrange; Said rack body member also can adopt pure magnesium or polymer to process.So, also all within this utility model protection domain, give unnecessary details no longer one by one here.
Claims (10)
1. micropore ACS can absorb support; Comprise rack body member and connecting rod; The adjacent stent main component is connected through connecting rod, it is characterized in that said rack body member with or connecting rod be provided with at least one micropore, said rack body member is pure magnesium or magnesium alloy or polymer.
2. micropore ACS as claimed in claim 1 can absorb support; It is characterized in that said rack body member is the regular serpentine rings that arc section links to each other and forms with snakelike section; Said connecting rod is uniformly distributed with the arc section wave crest place that is connected in the adjacent stent main component at interval, and said micropore is located on snakelike section.
3. micropore ACS as claimed in claim 2 can absorb support, it is characterized in that said rack body member outside is provided with medication coat, and said micropore contains visible development enhancing substance under medicine or the development of X line or MRI, the CT.
4. micropore ACS as claimed in claim 3 can absorb support, it is characterized in that said micropore rounded or square or triangle or ellipse or flute profile.
5. micropore ACS as claimed in claim 4 can absorb support, it is characterized in that said micropore is through hole or blind hole.
6. can absorb support like the described micropore ACS of claim 1-5, it is characterized in that said micropore adopts linear array or non-rectilinear to arrange.
7. micropore ACS as claimed in claim 6 can absorb support, it is characterized in that said polymer is polylactic acid, polyglycolic acid, gathers a kind of in anhydride and the copolymer thereof.
8. micropore ACS as claimed in claim 6 can absorb support, it is characterized in that said polymer is a kind of in caprolactone modification polymer, Polyethylene Glycol, hydrogel, photocuring hydrogel, the terminal diol, derivatives.
9. micropore ACS as claimed in claim 6 can absorb support, it is characterized in that said polymer is a kind of in polysaccharide, protein, polyester, PHA, polyamide, polycaprolactone, polyester, polyesteramide, polyvinyl alcohol, propylene glycol carbonic acid, the polyacrylate.
10. can absorb support like each described micropore of claim 6, it is characterized in that said magnesium alloy is magnalium or magnesium-zinc alloy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120163828 CN202184823U (en) | 2011-05-20 | 2011-05-20 | Microporous absorbable coronary stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120163828 CN202184823U (en) | 2011-05-20 | 2011-05-20 | Microporous absorbable coronary stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202184823U true CN202184823U (en) | 2012-04-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120163828 Expired - Fee Related CN202184823U (en) | 2011-05-20 | 2011-05-20 | Microporous absorbable coronary stent |
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| Country | Link |
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| CN (1) | CN202184823U (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110465A (en) * | 2012-11-08 | 2013-05-22 | 哈尔滨工程大学 | Magnesium alloy coronary support frame |
| CN103169556A (en) * | 2013-02-22 | 2013-06-26 | 深圳市信立泰生物医疗工程有限公司 | Completely-biodegradable support capable of developing and preparation method thereof |
| CN104644295A (en) * | 2014-12-19 | 2015-05-27 | 上海百心安生物技术有限公司 | Absorbable luminal stent and preparation method thereof |
| CN104888282A (en) * | 2015-05-05 | 2015-09-09 | 乐普（北京）医疗器械股份有限公司 | A degradable zinc-based microporous drug-loaded stent and its preparation method |
| WO2018153300A1 (en) * | 2017-02-21 | 2018-08-30 | 上海微创医疗器械（集团）有限公司 | Stent |
| CN108852568A (en) * | 2018-07-19 | 2018-11-23 | 四川兴泰普乐医疗科技有限公司 | A kind of intravascular stent and preparation method thereof of multicoat autography |
| CN109330753A (en) * | 2018-08-20 | 2019-02-15 | 江苏大学 | A drug-loaded stent to improve blood circulation |
| CN109394398A (en) * | 2018-09-14 | 2019-03-01 | 江西瑞济生物工程技术股份有限公司 | A kind of degradable foldable bioamnion complex repairation bracket |
| CN110051889A (en) * | 2019-04-24 | 2019-07-26 | 中国科学院长春应用化学研究所 | A kind of acid fiber by polylactic enhancing intravascular stent and preparation method thereof |
| CN110279501A (en) * | 2019-07-18 | 2019-09-27 | 中科益安医疗科技（北京）股份有限公司 | A kind of medical embedded coronary artery bracket |
-
2011
- 2011-05-20 CN CN 201120163828 patent/CN202184823U/en not_active Expired - Fee Related
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103110465B (en) * | 2012-11-08 | 2015-02-25 | 江阴宝易德医疗科技有限公司 | Magnesium alloy coronary support frame |
| CN103110465A (en) * | 2012-11-08 | 2013-05-22 | 哈尔滨工程大学 | Magnesium alloy coronary support frame |
| CN103169556A (en) * | 2013-02-22 | 2013-06-26 | 深圳市信立泰生物医疗工程有限公司 | Completely-biodegradable support capable of developing and preparation method thereof |
| CN103169556B (en) * | 2013-02-22 | 2015-04-15 | 深圳市信立泰生物医疗工程有限公司 | Completely-biodegradable support capable of developing and preparation method thereof |
| US10779974B2 (en) | 2014-12-19 | 2020-09-22 | Shanghai Bio-Heart Biological Technology Co., Ltd. | Absorbable endoluminal stent and production method thereof |
| CN104644295A (en) * | 2014-12-19 | 2015-05-27 | 上海百心安生物技术有限公司 | Absorbable luminal stent and preparation method thereof |
| CN104888282A (en) * | 2015-05-05 | 2015-09-09 | 乐普（北京）医疗器械股份有限公司 | A degradable zinc-based microporous drug-loaded stent and its preparation method |
| WO2018153300A1 (en) * | 2017-02-21 | 2018-08-30 | 上海微创医疗器械（集团）有限公司 | Stent |
| US11213413B2 (en) | 2017-02-21 | 2022-01-04 | Shanghai Microport Medical (Group) Co., Ltd. | Stent |
| CN108852568A (en) * | 2018-07-19 | 2018-11-23 | 四川兴泰普乐医疗科技有限公司 | A kind of intravascular stent and preparation method thereof of multicoat autography |
| CN109330753A (en) * | 2018-08-20 | 2019-02-15 | 江苏大学 | A drug-loaded stent to improve blood circulation |
| WO2020052136A1 (en) * | 2018-09-14 | 2020-03-19 | 江西瑞济生物工程技术股份有限公司 | Degradable foldable biological amniotic membrane composite repair stent |
| CN109394398A (en) * | 2018-09-14 | 2019-03-01 | 江西瑞济生物工程技术股份有限公司 | A kind of degradable foldable bioamnion complex repairation bracket |
| US11426294B2 (en) | 2018-09-14 | 2022-08-30 | Jiangxi Ruiji Biotechnology Co., Ltd | Degradable foldable biological amniotic membrane composite repair stent |
| CN110051889A (en) * | 2019-04-24 | 2019-07-26 | 中国科学院长春应用化学研究所 | A kind of acid fiber by polylactic enhancing intravascular stent and preparation method thereof |
| CN110279501A (en) * | 2019-07-18 | 2019-09-27 | 中科益安医疗科技（北京）股份有限公司 | A kind of medical embedded coronary artery bracket |
| WO2021008599A1 (en) * | 2019-07-18 | 2021-01-21 | 史忠林 | Medical implanted coronary stent |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120411 Termination date: 20140520 |