CN201955305U - Optical fiber type sensing system based on surface plasma resonance and stimulated Raman scattering - Google Patents
Optical fiber type sensing system based on surface plasma resonance and stimulated Raman scattering Download PDFInfo
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- CN201955305U CN201955305U CN2010206885716U CN201020688571U CN201955305U CN 201955305 U CN201955305 U CN 201955305U CN 2010206885716 U CN2010206885716 U CN 2010206885716U CN 201020688571 U CN201020688571 U CN 201020688571U CN 201955305 U CN201955305 U CN 201955305U
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- 239000013307 optical fiber Substances 0.000 title claims abstract description 61
- 238000001069 Raman spectroscopy Methods 0.000 title claims abstract description 17
- 239000000835 fiber Substances 0.000 claims abstract description 66
- 239000002184 metal Substances 0.000 claims abstract description 37
- 229910052751 metal Inorganic materials 0.000 claims abstract description 37
- 239000000523 sample Substances 0.000 claims abstract description 33
- 230000010287 polarization Effects 0.000 claims abstract description 31
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims abstract description 7
- 239000002120 nanofilm Substances 0.000 claims abstract 4
- 230000000694 effects Effects 0.000 claims description 17
- 239000010931 gold Substances 0.000 claims description 15
- 238000001105 surface plasmon resonance spectrum Methods 0.000 claims description 9
- 230000002708 enhancing effect Effects 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 4
- 238000001755 magnetron sputter deposition Methods 0.000 claims description 3
- 229910052709 silver Inorganic materials 0.000 claims description 3
- 239000004332 silver Substances 0.000 claims description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 abstract description 4
- 238000012544 monitoring process Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 description 19
- 238000001514 detection method Methods 0.000 description 14
- 238000000151 deposition Methods 0.000 description 8
- 230000008021 deposition Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000008569 process Effects 0.000 description 5
- 239000012528 membrane Substances 0.000 description 4
- 239000002086 nanomaterial Substances 0.000 description 4
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 238000004833 X-ray photoelectron spectroscopy Methods 0.000 description 2
- 239000012491 analyte Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000003574 free electron Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
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Abstract
基于表面等离子共振和受激拉曼散射的光纤型传感系统，包括宽带光源，P型偏振片，聚焦凸透镜，偏振控制器，光纤分束器，光纤斜面端，SPR探头和光纤光谱仪；P型偏振片位于宽带光源和聚焦凸透镜之间，聚焦凸透镜将偏振宽带光耦合入偏振控制器，偏振控制器与光纤分束器的一个输入端连接，光纤光谱仪与光纤分束器的另一个输入端连接，光纤斜面端与光纤分束器的一个输出端连接，SPR探头与光纤分束器的另一个输出端连接；光纤斜面端的自由端呈斜面；SPR探头包括光纤，裸露纤芯的端面有第一金属膜、周围有第二金属膜，第二金属膜表面有纳米膜，纳米膜上有敏感膜。本实用新型具有通用性好，灵敏度高，稳定性好，可实现远程监测的优点。
Fiber-optic sensing system based on surface plasmon resonance and stimulated Raman scattering, including broadband light source, P-type polarizer, focusing convex lens, polarization controller, fiber beam splitter, fiber optic bevel end, SPR probe and fiber optic spectrometer; P-type The polarizer is located between the broadband light source and the focusing convex lens. The focusing convex lens couples the polarized broadband light into the polarization controller. The polarization controller is connected to one input end of the fiber optic beam splitter, and the fiber optic spectrometer is connected to the other input end of the fiber optic beam splitter. , the optical fiber inclined plane end is connected with one output end of the optical fiber beam splitter, and the SPR probe is connected with the other output end of the optical fiber beam splitter; the free end of the optical fiber inclined plane end is inclined; the SPR probe includes an optical fiber, and the end face of the exposed fiber core has a first There is a second metal film around the metal film, a nano film on the surface of the second metal film, and a sensitive film on the nano film. The utility model has the advantages of good versatility, high sensitivity and good stability, and can realize remote monitoring.
Description
Technical field
The utility model relates to a kind of optical-fiber type sensor-based system based on surface plasma resonance and stimulated Raman scattering.
Technical background
The biochemical sensitive technology is widely applied to fields such as basic life science, medical science, biochemistry, environment and food inspection, traditional biosensor technique is difficult to realize that the interactional real-time online of bioanalysis detects, as x-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES) etc., cost an arm and a leg, equipment is huge, experiment condition harshness (high vacuum), in addition some immunoassay technology commonly used, as fluorescence immunoassay, generally all need mark, and the test process complexity, the test duration is longer.Along with the development of measuring technology, people have higher requirement to the precision and the diversity that detect.
The utility model content
For overcoming the above-mentioned shortcoming of prior art, the utility model provides a kind of versatility good, highly sensitive, and good stability can be realized the miniature optical-fiber type sensor-based system based on surface plasma resonance and stimulated Raman scattering of remote monitoring.
Optical-fiber type sensor-based system based on surface plasma resonance and stimulated Raman scattering, comprise the wideband light source that sends incident light, incident light is changed into the P type polaroid of polarization broadband light, focus on convex lens, regulate the Polarization Controller of polarization broadband polarisation of light, enhancing resonance effect, fiber optic splitter prevents that light wave from reflecting to form the optical fiber beveled end of self-excitation, enter SPR probe that produces SPR spectrum in the analyzed solution and the fiber spectrometer that detects resonant wavelength;
Described P type polaroid is between described wideband light source and focusing convex lens, described focusing convex lens are coupled into the polarization broadband light in the described Polarization Controller, described Polarization Controller is connected with an input end of fiber optic splitter, described fiber spectrometer is connected with another input end of fiber optic splitter, described optical fiber beveled end is connected with an output terminal of fiber optic splitter, and described SPR probe is connected with another output terminal of described fiber optic splitter; The free end of described optical fiber beveled end is the inclined-plane;
Described SPR probe comprises the optical fiber that the head fibre core is exposed, the end face uniform deposition of exposed fibre core has first metal film as end mirror, side face uniform deposition one deck second metal film of exposed fibre core, described second metallic film surface is modified with nanometer film, deposition one deck sensitive membrane on the described nanometer film.
Further, described first metal film is golden film or the silverskin of the about 300nm of thickness; Described second metal film is the golden film (Au film) of 50nm ± 0.1nm for the thickness that forms by the rf magnetron sputtering deposition; Described nanometer film is for to modify the Au nanometer film that forms by induced with laser on the Au film.
Further, described fiber optic splitter is 2 * 2 fiber optic splitters.
Further, the optical fiber of described SPR probe is general single mode fiber.
" connection " of the present utility model is meant the connection at light path, for example described optical fiber polarization controller is connected with an end of described 2 * 2 fiber optic splitter input ends, promptly be interpreted as " end that is input to 2 * 2 fiber optic splitter input ends from the light signal of optical fiber polarization controller output ", also in like manner explain in other places.
Surface plasma body resonant vibration (Surface Plasmon Resonance, SPR) technology is that the evanescent wave that light produces when glass and the generation total reflection of metal interface place can cause the free electron generation surface plasma of metal surface, when the frequency of surface plasma and evanescent wave is identical with wave number, will produce surface plasma body resonant vibration (SPR), the specific inductive capacity of the main and metal film of its resonant wavelength, the concentration of solution to be measured, parameters such as refractive index are closely related, therefore under the condition of other parameter constants, there be corresponding relation between the resonant wavelength of optical fiber SPR sensor and the solution refractive index to be measured only changing solution to be measured.The SPR technology has determinand and need not purifying, sample and need not mark, dynamic process, highly sensitive, the advantage such as background interference is little, response speed is fast, detection time is short of monitoring reaction in real time, has obtained at present paying attention to widely and developing rapidly; And the surface enhanced Raman scattering effect of metal Nano structure (SERS) makes the Raman signal be adsorbed on the metal surface molecule with SERS activity compare with the Raman signal of equal number molecule in the solution to have taken place up to 10
6Huge enhancing, cause the SERS technology that surface mass is had high detection sensitivity and selectivity, can be on molecular level real-time monitored to the various materials in interface " fingerprint " information (chemical constitution and composition).
The optical fiber sensor-based system is that optical fiber technology and SPR/SERS technology are combined, the responsive part of SPR is narrowed down to optical fiber core diameter size, fibre diameter is generally below 600um, the length of SPR probe is at 5mm-25mm, very small and exquisite, and, need not the mark sample during detection, molecular structure and activity have been kept, highly sensitive, use the conduction of optical fiber simultaneously, can realize remote online detection, the testing process aspect is quick, is microminiaturized the extending naturally of requiring of technical development from now on and system.
The utility model combines surface plasma resonance (SPR) effect and optical fiber technology.The surface enhanced Raman scattering effect of SPR technology and metal Nano structure has the characteristics of high detection sensitivity, can make Raman signal obtain huge enhancing, and accuracy of detection improves; Adopt optical fiber as sensor probe, structure is small and exquisite, helps the microminiaturization of system, has overcome the influence that is subject to extraneous factors such as physical construction, light source fluctuation in the prism-type SPR structure simultaneously.
The building method of end reflection formula optical fiber probe is to get certain-length at optic fibre end, optical fiber is general single mode fiber, covering and the coat outer fibre core erode, the end face of polishing fiber, deposit layer of metal film (gold or silver) as completely reflecting mirror at optic fibre end, then sedimentary organism sensitive membrane and metal A u film on one section fibre core of this end, and on metal A u film, modify the Au nanometer film.Wideband light source is through P type polaroid with after focusing on convex lens in the coupled into optical fibres Polarization Controller, behind 2 * 2 fiber optic splitters, input to the SPR probe, in the Optical Fiber Transmission process, the light that satisfies the SPR resonant condition will be after being reflected by the metal film completely reflecting mirror, through resonance, produce SPR spectrum, the SPR spectrum of generation oppositely exports fiber spectrometer to through 2 * 2 fiber optic splitters, observes the SPR spectrum of analyte.
The utlity model has highly versatile, highly sensitive, stability and reproduction type are good, cheap, can realize miniature and advantage remote detection.
Description of drawings
Fig. 1 is a synoptic diagram of the present utility model.
Fig. 2 is the structural representation of SPR probe.
Embodiment
With reference to accompanying drawing, further specify the utility model:
Optical-fiber type sensor-based system based on surface plasma resonance and stimulated Raman scattering, comprise the wideband light source 1 that sends incident light, incident light is changed into the P type polaroid 2 of polarization broadband light, focus on convex lens 3, regulate the Polarization Controller 4 of polarization broadband polarisation of light, enhancing resonance effect, fiber optic splitter 5 prevents that light wave from reflecting to form the optical fiber beveled end 6 of self-excitation, enter SPR probe 8 that produces SPR spectrum in the analyzed solution and the fiber spectrometer 7 that detects resonant wavelength;
Described P type polaroid 2 is between described wideband light source 1 and focusing convex lens 3, described focusing convex lens 3 are coupled into the polarization broadband light in the described Polarization Controller 4, described Polarization Controller 4 is connected with an input end of fiber optic splitter 5, described fiber spectrometer 7 is connected with another input end of fiber optic splitter 5, described optical fiber beveled end 6 is connected with an output terminal of fiber optic splitter 5, and described SPR probe 8 is connected with another output terminal of described fiber optic splitter 5; The free end of described optical fiber beveled end 6 is the inclined-plane;
Described SPR probe 8 comprises the optical fiber 81 that the head fibre core is exposed, the end face uniform deposition of exposed fibre core 82 has first metal film 83 as end mirror, side face uniform deposition one deck second metal film 84 of exposed fibre core 82,84 finishinges of described second metal film have nanometer film 85, uniform deposition one deck sensitive membrane 86 on the described nanometer film.
Described first metal film 83 is golden film or the silverskin of the about 300nm of thickness; Described second metal film 84 is the golden film (Au film) of 50nm ± 0.1nm for the thickness that forms by the rf magnetron sputtering deposition; Described nanometer film 85 is for to modify the Au nanometer film that forms by induced with laser on the Au film.
Described fiber optic splitter 5 is 2 * 2 fiber optic splitters.
The optical fiber of described SPR probe 8 is general single mode fiber.
" connection " of the present utility model is meant the connection at light path, for example described optical fiber polarization controller is connected with an end of described 2 * 2 fiber optic splitter input ends, promptly be interpreted as " end that is input to 2 * 2 fiber optic splitter input ends from the light signal of optical fiber polarization controller output ", also in like manner explain in other places.
Surface plasma body resonant vibration (Surface Plasmon Resonance, SPR) technology is that the evanescent wave that light produces when glass and the generation total reflection of metal interface place can cause the free electron generation surface plasma of metal surface, when the frequency of surface plasma and evanescent wave is identical with wave number, will produce surface plasma body resonant vibration (SPR), the specific inductive capacity of the main and metal film of its resonant wavelength, the concentration of solution to be measured, parameters such as refractive index are closely related, therefore under the condition of other parameter constants, there be corresponding relation between the resonant wavelength of optical fiber SPR sensor and the solution refractive index to be measured only changing solution to be measured.The SPR technology has determinand and need not purifying, sample and need not mark, dynamic process, highly sensitive, the advantage such as background interference is little, response speed is fast, detection time is short of monitoring reaction in real time, has obtained at present paying attention to widely and developing rapidly; And the surface enhanced Raman scattering effect of metal Nano structure (SERS) makes the Raman signal be adsorbed on the metal surface molecule with SERS activity compare with the Raman signal of equal number molecule in the solution to have taken place up to 10
6Huge enhancing, cause the SERS technology that surface mass is had high detection sensitivity and selectivity, can be on molecular level real-time monitored to the various materials in interface " fingerprint " information (chemical constitution and composition).
The optical fiber sensor-based system is that optical fiber technology and SPR/SERS technology are combined, the responsive part of SPR is narrowed down to optical fiber core diameter size, fibre diameter is generally below 600um, the length of SPR probe is at 5mm-25mm, very small and exquisite, and, need not the mark sample during detection, molecular structure and activity have been kept, highly sensitive, use the conduction of optical fiber simultaneously, can realize remote online detection, the testing process aspect is quick, is microminiaturized the extending naturally of requiring of technical development from now on and system.
The utility model combines surface plasma resonance (SPR) effect and optical fiber technology.The surface enhanced Raman scattering effect of SPR technology and metal Nano structure has the characteristics of high detection sensitivity, can make Raman signal obtain huge enhancing, and accuracy of detection improves; Adopt optical fiber as sensor probe, structure is small and exquisite, helps the microminiaturization of system, has overcome the influence that is subject to extraneous factors such as physical construction, light source fluctuation in the prism-type SPR structure simultaneously.
The building method of end reflection formula optical fiber probe is to get certain-length at optic fibre end, optical fiber is general single mode fiber, covering and the coat outer fibre core erode, the end face of polishing fiber, deposit layer of metal film (gold or silver) as completely reflecting mirror at optic fibre end, then sedimentary organism sensitive membrane and metal A u film on one section fibre core of this end, and on metal A u film, modify the Au nanometer film.Wideband light source is through P type polaroid with after focusing on convex lens in the coupled into optical fibres Polarization Controller, behind 2 * 2 fiber optic splitters, input to the SPR probe, in the Optical Fiber Transmission process, the light that satisfies the SPR resonant condition will be after being reflected by the metal film completely reflecting mirror, through resonance, produce SPR spectrum, the SPR spectrum of generation oppositely exports fiber spectrometer to through 2 * 2 fiber optic splitters, observes the SPR spectrum of analyte.
Show as described in Figure 1, the SPR probe is applied in the system of measuring the solution refractive index, use incident light to be the wideband light source of wavelength 400nm to 1000nm, after handling, P type polaroid becomes the polarization broadband light, the line focus convex lens are coupled into optical fiber polarization controller, the effect of optical fiber polarization controller is by regulating polarization, reach better resonance effect, the polarization broadband light is through 2 * 2 fiber optic splitters, export an end and connect the optical fiber beveled end, prevent that light from reflecting back the formation self-excitation, the other end is connected to the SPR probe.The SPR probe directly is inserted into detected solution, after incident light arrives the SPR probe, produce the SPR effect with the solution medium interaction, through forming reflection SPR light after the completely reflecting mirror effect of fibre core end face, reflected light enters fiber spectrometer through another input end of 2 * 2 fiber optic splitters again.Through the relation curve between output reflection light intensity after the Computer Processing and the optical wavelength.The sensing range of spectrometer is 500-900nm, and resolution is 0.5nm, can detect the resonant wavelength that changes between the 500-900nm.If change measuring accuracy and sensitivity that more high-resolution spectrometer can further improve system, can change the spectrometer in the detection system simultaneously according to actual needs.
The utility model is easy to use flexibly, only needs the SPR probe is immersed analyzed solution, can detect the fluid to be measured change of refractive in real time, stability and favorable reproducibility by measuring resonant wavelength; Utilize fiber optic conduction and computer technology combination simultaneously, can realize transmitting light signal at a distance, satisfy the application that some catastrophe risk zones are detected.Its highly versatile, characteristics such as sensitivity height make it can be widely used in fields such as chemistry, biology and environmental medicine.
The described content of this instructions embodiment only is enumerating the way of realization of utility model design; protection domain of the present utility model should not be regarded as only limiting to the concrete form that embodiment states, protection domain of the present utility model also reach in those skilled in the art according to the utility model design the equivalent technologies means that can expect.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102095719A (en) * | 2010-12-30 | 2011-06-15 | 浙江工业大学 | Optical fiber type sensor system based on surface plasma resonance and stimulated Raman scattering |
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| CN102095719A (en) * | 2010-12-30 | 2011-06-15 | 浙江工业大学 | Optical fiber type sensor system based on surface plasma resonance and stimulated Raman scattering |
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Granted publication date: 20110831 Termination date: 20131230 |