CN201664579U - Blocking Structure of Hollow Fiber Blood Ultrafilter - Google Patents
Blocking Structure of Hollow Fiber Blood Ultrafilter Download PDFInfo
- Publication number
- CN201664579U CN201664579U CN2010201403473U CN201020140347U CN201664579U CN 201664579 U CN201664579 U CN 201664579U CN 2010201403473 U CN2010201403473 U CN 2010201403473U CN 201020140347 U CN201020140347 U CN 201020140347U CN 201664579 U CN201664579 U CN 201664579U
- Authority
- CN
- China
- Prior art keywords
- blood
- hollow fiber
- ultrafilter
- main cylinder
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 46
- 239000008280 blood Substances 0.000 title claims abstract description 46
- 239000012510 hollow fiber Substances 0.000 title claims abstract description 17
- 230000000903 blocking effect Effects 0.000 title 1
- 239000000463 material Substances 0.000 claims abstract description 24
- 229920002635 polyurethane Polymers 0.000 claims abstract description 9
- 239000004814 polyurethane Substances 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 3
- 239000003292 glue Substances 0.000 claims abstract 7
- 238000007789 sealing Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims 2
- 230000000740 bleeding effect Effects 0.000 claims 1
- 230000010100 anticoagulation Effects 0.000 abstract description 6
- 238000001631 haemodialysis Methods 0.000 abstract description 3
- 230000000322 hemodialysis Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 231100000252 nontoxic Toxicity 0.000 abstract description 3
- 230000003000 nontoxic effect Effects 0.000 abstract description 3
- 230000000704 physical effect Effects 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 2
- 206010028024 Mouth haemorrhage Diseases 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 235000012489 doughnuts Nutrition 0.000 description 12
- 238000000108 ultra-filtration Methods 0.000 description 7
- 239000000835 fiber Substances 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000004925 Acrylic resin Substances 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 102100023804 Coagulation factor VII Human genes 0.000 description 1
- 108010023321 Factor VII Proteins 0.000 description 1
- 108090001005 Interleukin-6 Proteins 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 229920000877 Melamine resin Polymers 0.000 description 1
- 108700012920 TNF Proteins 0.000 description 1
- 235000019013 Viburnum opulus Nutrition 0.000 description 1
- 244000071378 Viburnum opulus Species 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000032643 circulatory system process Effects 0.000 description 1
- 239000007799 cork Substances 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 239000008393 encapsulating agent Substances 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 229940012413 factor vii Drugs 0.000 description 1
- 229920001821 foam rubber Polymers 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- JDSHMPZPIAZGSV-UHFFFAOYSA-N melamine Chemical compound NC1=NC(N)=NC(N)=N1 JDSHMPZPIAZGSV-UHFFFAOYSA-N 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
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- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The utility model discloses a shutoff structure of hollow fiber blood ultrafilter, including casing and the hollow fiber who is used for filtering blood of setting in the casing, the side of casing is equipped with and filters the liquid mouth, and casing one end is equipped with into blood mouth, and the casing other end is equipped with the hemorrhage mouth, closes on the shutoff glue film that two port departments were equipped with fixed hollow fiber both ends respectively in the casing. Because the plugging glue layer only fixes two ends of the hollow fiber, the used materials are reduced, the cost is saved, the plugging glue layer adopts the polyurethane material which gradually draws attention of the medical field with excellent chemical and physical properties and excellent anticoagulation performance, and the special properties of the polyurethane material are utilized to effectively ensure that blood and dialysate do not leak mutually in the using process, so that the plugging glue layer is nontoxic and anticoagulation, and can ensure that the hemodialysis can be safely and reliably carried out.
Description
Technical field
The utility model relates to the ultrafilter art, refers in particular to a kind of plugging structure of doughnut blood ultrafiltration device.
Background technology
Medically, the extracorporal circulatory system process of carrying out when operations such as OH can activate inflammatory reaction and discharge some humoral factors, comprise the slow factor VII of swashing and complement fragment and endotoxin, impel the expression and the release of cell factor or various endothelial cell and interleukin, finally cause pouring into the back syndrome.Though the doctor operates as much as possible meticulously in operation, guarantee the operation quality, and when operation, adopt safety prevention measure, and the material that on material, as far as possible uses good biocompatibility, but still above-mentioned situation inevitably takes place.
In clinical use progressively, doctors find hyperfiltration technique after reducing extracorporal circulatory system inflammatory reaction and the immunology activation aspect played enormous function.Because hyperfiltration technique can and promote that patient is good what postoperative recovery play a part, is extended to rapidly in all cardiopulmonary bypass surgeries at blood conservation.
The Hollow Fiber Ultrafiltration technology has characteristics such as the unit volume intimal surface is long-pending greatly, power consumption is low, efficient is high, delay is low.Its operation principle is that blood passes through housing, become under the turbulence state in hollow fiber ultrafiltration membrane or film outer surface distributes and flows at certain pressure, solvent or become ultrafiltrate by film through collection less than the dam material of molecular weight of film, then dammed greater than the dam material and the colloidal solid of molecular weight of film, as will return in the blood time, the concentration of its blood can raise gradually, is commonly called as concentrate, so repeatedly, thus realize the concentrated purpose of blood.Present existing ultrafilter, fiber is cast in the pleurodiaphragmatic in terspace spare shell by the material of sealing fiber, and tool ties up in the whole ultrafiltration pipe and is cast with encapsulant, makes materials demand many, the cost height; Simultaneously, the material of sealing hollow fibre generally has: epoxy resin, cork, foam rubber, phenolic resins, melamine, acrylic resin, silicon rubber etc.But above-mentioned material is subjected to the physicochemical property of itself, adhesive property, and influences such as processing performance and bio-safety performance should not be used as the ultrafilter plugging material.
The utility model content
The utility model is at the disappearance of prior art existence, and its main purpose provides a kind of plugging structure of doughnut blood ultrafiltration device, it is safe and reliable, at the bottom of the use cost, make easily, easy to assembly.
For achieving the above object, the utility model adopts following technical scheme:
A kind of plugging structure of doughnut blood ultrafiltration device, include housing and the doughnut that is used for filtering blood that is arranged in the housing, the side of housing is provided with the filtered solution mouth, housing one end is provided with blood inlet, the housing other end is provided with blood outlet, closes on the two-port place and be provided with the fixedly shutoff glue-line at doughnut two ends respectively in housing.
As a kind of preferred version, described housing is made up of main cylinder and the end cap that is installed on the main cylinder two ends.
As a kind of preferred version, described main cylinder outside wall surface near near the opening of main cylinder both sides respectively one extend an outer sleeve, this outer sleeve combines with end cap inside and forms a containing cavity that can install blood.
As a kind of preferred version, the both sides opening part outer rim of described outer sleeve and main cylinder forms a groove, and the filtered solution mouth is arranged at the groove side.
As a kind of preferred version, described blood inlet is positioned on the end cap, and blood outlet is positioned at the other end and covers.
As a kind of preferred version, described end cap is connected with main cylinder by sealing ring.
As a kind of preferred version, described shutoff glue-line is between end cap inwall and main cylinder opening.
As a kind of preferred version, described shutoff glue-line is a polyurethane material
The utility model compared with prior art has tangible advantage and beneficial effect, particularly, as shown from the above technical solution, by being provided with the shutoff glue-line, the shutoff glue-line is only fixed the two ends of doughnut, reduced the use material of shutoff glue-line, save cost, and this shutoff glue-line adopts the chemistry with excellence, physical property and remarkable anticoagulation function cause the polyurethane material that medical circle is paid attention to gradually, replaced traditional plugging material, utilize the property of polyurethane material can guarantee effectively that in use blood and dislysate do not leak through with each other, nontoxic, anticoagulation, make the hemodialysis can safe and reliable carrying out.And, by being provided with sealing ring with the outer sleeve place of combining, make blood can not leak into the external world, thereby well guaranteed the service property (quality) of product in end cap is inner.
For more clearly setting forth architectural feature of the present utility model and effect, come the utility model is elaborated below in conjunction with accompanying drawing and specific embodiment:
Description of drawings
Figure is the concrete structure diagrammatic sketch of the preferred embodiment of the utility model.
The accompanying drawing identifier declaration:
1, housing 121, blood inlet
11, main cylinder 13, end cap
12, end cap 131, blood outlet
14, outer sleeve 2, doughnut
15, groove 3, O RunddichtringO
16, filtered solution mouth 4, shutoff glue-line
17, containing cavity
The specific embodiment:
Shown in accompanying drawing, it has demonstrated the concrete structure of the preferred embodiment of the utility model, include housing 1 and the doughnut 2 that is arranged in the housing 1, this housing 1 includes main cylinder 11 and is installed on the end cap 12 at main cylinder two ends, 13, this main cylinder 11 is cylindric, and its both ends open, these main cylinder 11 outside wall surface near near the main cylinder 11 both sides openings respectively one extend an outer sleeve 14, this outer sleeve 14 forms a groove 15 with the both sides opening part outer rim of main cylinder 11, these outer sleeve 14 1 sides extend a filtered solution mouth 16, this filtered solution mouth 16 is communicated with groove 15, makes water and part IL-6 in the blood plasma that ultrafilter in use separates out from the bloody path side, TNFa, C
3A, C
5Little molecule solute such as a can flow out from this filtered solution mouth 16.Sealing cover is in two opening parts of main cylinder 11 respectively for two end cap 12,13, and these two end cap 12,13 inner formation one that combine with outer sleeve 14 can be installed the containing cavity 17 of blood.One end cap 12 is axially arranged with a blood inlet 121, and another end cap 13 is axially arranged with a blood outlet 131.
In the present embodiment, be provided with an O RunddichtringO 3 in two end cap 12,13 inside with outer sleeve 14 places of combining, this O RunddichtringO 3 is a silastic material, is used to prevent that the inner blood of ultrafilter from can not leak into the external world.And in above-mentioned containing cavity 17, be provided with a shutoff glue-line 4, and this shutoff glue-line 4 is between end cap 12,13 inwalls and main cylinder 11 openings, and this shutoff glue-line 4 is used for fixing the two ends of doughnut 2, and this shutoff glue-line 4 is a polyurethane material.
The groundwork principle that present embodiment is described in detail in detail is as follows:
When blood enters ultrafilter, hollow-fibre membrane in the ultrafilter is a malleation, film is outward atmospheric pressure or negative pressure, under the effect of both sides differential pressure of membrane, small-molecule substance in the blood leaches outside the pipe by the doughnut membrane micropore, hollow-fibre membrane selectively keeps the above solute of a certain special diameter, filtered solution does not contain protein and blood constituent, filtered solution flows out from the filtered solution mouth of this ultrafilter, thereby can remove complement and inflammatory mediator in the extracorporal circulatory system, concentrate out red blood cell, all blood constituents such as plasma protein are failed back and are given patient, improve patient's snowball hematocrit rapidly, reduce a series of complication of postoperative and use diuretic, alleviate the kidney burden, help the recovery of body interior function.
Design focal point of the present utility model is, by being provided with the shutoff glue-line, the shutoff glue-line is only fixed the two ends of doughnut, reduced the use material of shutoff glue-line, save cost, and this shutoff glue-line adopts chemistry, physical property and remarkable anticoagulation function with excellence to cause the polyurethane material that medical circle is paid attention to gradually, replaced traditional plugging material, utilize the property of polyurethane material can guarantee effectively that in use blood and dislysate do not leak through with each other, nontoxic, anticoagulation, make the hemodialysis can safe and reliable carrying out.And, by being provided with the O RunddichtringO with the outer sleeve place of combining, make blood can not leak into the external world, thereby well guaranteed the service property (quality) of product in end cap is inner.
The above, it only is preferred embodiment of the present utility model, be not that technical scope of the present utility model is imposed any restrictions, so every foundation technical spirit of the present utility model all still belongs in the scope of technical solutions of the utility model any trickle modification, equivalent variations and modification that above embodiment did.
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201403473U CN201664579U (en) | 2010-03-23 | 2010-03-23 | Blocking Structure of Hollow Fiber Blood Ultrafilter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201403473U CN201664579U (en) | 2010-03-23 | 2010-03-23 | Blocking Structure of Hollow Fiber Blood Ultrafilter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201664579U true CN201664579U (en) | 2010-12-08 |
Family
ID=43265531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010201403473U Expired - Lifetime CN201664579U (en) | 2010-03-23 | 2010-03-23 | Blocking Structure of Hollow Fiber Blood Ultrafilter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201664579U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104902941A (en) * | 2013-02-12 | 2015-09-09 | 东丽株式会社 | Blood purification column |
| CN105592869A (en) * | 2013-10-03 | 2016-05-18 | 旭化成医疗株式会社 | Blood treatment filter and blood treatment filter manufacturing method |
-
2010
- 2010-03-23 CN CN2010201403473U patent/CN201664579U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104902941A (en) * | 2013-02-12 | 2015-09-09 | 东丽株式会社 | Blood purification column |
| CN104902941B (en) * | 2013-02-12 | 2017-05-03 | 东丽株式会社 | blood purification column |
| CN105592869A (en) * | 2013-10-03 | 2016-05-18 | 旭化成医疗株式会社 | Blood treatment filter and blood treatment filter manufacturing method |
| CN105592869B (en) * | 2013-10-03 | 2018-09-04 | 旭化成医疗株式会社 | The manufacturing method of blood processing filter and blood processing filter |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20101208 |