CN201150691Y - Adjustable inner injector for pulsing cardiac muscle - Google Patents

Abstract

The utility model relates to an adjustable internal beating myocardial injector, which comprises a tube, a pintle, a needle, an adjusting ring and an outer sleeve pipe. The adjustable internal beating myocardial injector is characterized in that the adjusting ring axially slides along the needle cylinder and is equipped with a locking screw. The outer sleeve pipe is sleeved in the tube from the needle direction to the adjusting ring, the needle can extend out from a rubber pad arranged at the front end of the outer sleeve pipe, and the length of the exposed needle portion is a length of puncture in ventricular muscle. The wall of the tube utilizes double scales (volume scales and length scales) which are capable of controlling injection amount and needle insertion depth. The front end of the needle pin is a dip type projection, which can effectively reduce residual dead space after injection, and the needle is fixedly connected with the tube by screw threads. The adjustable internal beating myocardial injector can effectively avoid hemorrhage at the needle eye and overflow of infusion and adjust the effective length of the needle, can be widely adaptable to hearts with various sizes ( means myocardial with different thickness), and effectively avoids the danger of mistakenly myocardial penetrating to the chamber of heart. Therefore, the adjustable internal beating myocardial injector is convenient in operation, high in practicality, and is particularly adaptable to internal injection of beating myocardium.

Description

Adjustable pulsatile intramyocardial injector

technical field

The utility model belongs to the field of clinical medicine and research, in particular to an adjustable pulsating intramyocardial injector for cell transplantation and implantation of various gene carriers into pulsating myocardial tissue.

Background technique

At present, cell transplantation technology and gene technology have been more and more widely used in the treatment of various heart diseases, such as transplanting bone marrow stem cells or autologous atrial myocytes into autologous ventricular myocytes to treat ischemic cardiomyopathy, and injecting allogeneic ventricular myocytes into Plant embryonic stem cells and embryonic cardiomyocytes to rebuild cardiac pacemaker to treat various types of bradyarrhythmia; inject various gene vectors carrying different target genes directly into the myocardium through gene technology, or inject target cells after transfection into Inside the myocardium, exploring new ways to treat heart disease. Some of the above treatment options have entered the stage of clinical trials. When using the above technique to inject the infusion into the myocardium for transplantation, the method of injecting the infusion into the beating myocardium under direct vision is often used during thoracotomy. This method has the advantages of simple operation and reliable injection effect. At present, experimenters and clinicians mostly use disposable TB empty needles (tuberculin syringes) as injection tools during this operation. The TB empty needle has a small tip and precise scale, so it has the advantages of less myocardial damage and easy quantification. However, injection into the beating myocardium has its particularity, that is, the beating myocardium is in a state of continuous contraction and relaxation, and the frequency is relatively fast (60-120 times/min); the blood supply in the myocardium is rich, and after the needle is withdrawn, It is very easy to bleed and cause the injection to overflow and lose; the inside of the myocardium is the heart chamber, and if the injection is too deep, the injection will enter the heart chamber, resulting in serious complications such as vascular embolism. In addition, the injection (such as cell suspension) is usually relatively viscous, while the needle tip of the TB empty needle is small, and the resistance during injection is relatively high, which sometimes causes the needle to pop out and penetrate into the heart cavity, and the injection overflows from the detachment, resulting in injection failure.

Obviously, disposable TB empty needles cannot meet the above special requirements. In view of this situation, it is necessary to design a special injection device that is more suitable for the beating myocardium, so as to solve the above-mentioned problems and meet the various technical requirements for injection.

Contents of the invention

The technical problem to be solved by the utility model is to overcome the existing defects and deficiencies, and to provide an adjustable pulsating intramyocardial injector more suitable for pulsating myocardium.

The technical scheme of the utility model is as follows:

An adjustable pulsating intramyocardial injector, including a syringe, a pintle, a needle, an adjustment ring and an outer cannula, is characterized by:

1) There is an adjustment ring outside the syringe, which can slide along the wall of the syringe, and a locking screw is provided on the adjustment ring;

2) There is an outer casing outside the syringe, and a rubber pad at the front end;

3) The connection between the needle and the barrel is fixed by threads;

4) The front end of the piston of the needle pin is a protruding protrusion;

5) There are double scale marks on the wall of the syringe, that is, volume scale and length scale;

6) The length of the needle is 3cm, and the diameter of the needle is 0.5-1.0mm.

The needle passes through the rubber pad of the outer cannula, and the length c of the needle piercing into the ventricular muscle is adjusted (c=a-b), where a is the distance from the needle tip to the front end of the adjustment ring, and b is the total length of the outer cannula.

The adjusting ring of the utility model can slide axially along the needle barrel, and the adjusting ring is provided with a locking screw, which can firmly fix the adjusting ring on the preset scale on the outer wall of the syringe, thereby realizing precise control of the length of the exposed needle. The outer cannula is inserted into the needle barrel from the direction of the needle to the adjustment ring, and the needle passes through the rubber pad at the front end of the outer cannula. The exposed part of the needle is the length that can penetrate into the ventricular muscle. The length of the needle is fixed, which can prevent the needle from going too deep into the myocardium and penetrating the ventricular wall, so that the injection can directly enter the heart cavity, resulting in serious complications of vascular embolism and uncontrollable bleeding in the heart cavity after the needle is withdrawn. After the injection is completed and the needle is withdrawn, the purpose of compressing the myocardium to stop bleeding and preventing the injection from overflowing from the myocardium can be achieved through the outer cannula and the rubber pad at its front end.

The front end of the needle plug is a protruding protrusion, which can effectively reduce the residual dead space after injection, and avoid problems such as waste of injection and formation of air bubbles. The connection between the needle and the syringe is fixed by threads, which can effectively prevent the needle from falling off or popping out. The syringe wall is marked with double scales (volume scale and length scale), which is beneficial to control the amount of infusion, and control the position of the adjustment ring and the outer sleeve to indirectly control the length of the exposed needle (that is, the depth of the needle). The needle is lengthened to 3cm, so that the length of the needle can be adjusted in a sufficient range, so as to meet the needs of different thickness myocardium; the needle diameter is 0.5-1.0mm, which can ensure that the infusion can pass through the needle and enter the myocardium smoothly.

As an adjustable pulsating intramyocardial injector, the utility model has the following advantages:

1. The length of the exposed needle can be adjusted, so it is widely applicable to various sizes of hearts and different thicknesses of the myocardium, effectively avoiding the danger of penetrating the myocardium and straying into the heart cavity.

2. Utilizing the injector can effectively prevent the bleeding at the eye of the needle and the spillage of injections (such as cells, genes and their carriers).

3. The needle wall is thin and the caliber is relatively large, so that cells, etc. are not easily damaged by extrusion and can pass through smoothly.

4. The improved protrusion at the front end of the needle plug can avoid the waste of injections (cells, etc.) and the formation of air bubbles.

5. The syringe and the needle are connected by threads to prevent the danger of the needle coming out due to the viscous injection liquid.

6. The entire injection process can be completed at one time, and the operation is fast and convenient.

7. The whole device is easy to operate and has strong practicability, and is especially suitable for injecting into beating myocardium.

Description of drawings

Fig. 1 is a three-dimensional sectional view of the structure of the utility model;

Fig. 2 is a front view of the utility model;

Fig. 3 is a main sectional view of the structure of the utility model;

Fig. 4 is a cross-sectional view of an outer casing;

Figure 5 is a sectional view of the injector;

Figure 6 is a three-dimensional schematic view of the adjustment ring;

Fig. 7 is a partial cutaway side view of the adjustment ring.

Detailed ways

Below according to Fig. 1-Fig. 3, the embodiment of an adjustable pulsating intramyocardial injector of the present invention is provided, and be described in detail, so that those skilled in the art are more likely to understand the structural features and functional characteristics of the present invention, and It is not used to limit the scope of the present utility model.

Please refer to Figure 1-Figure 7, as shown:

The utility model is an adjustable pulsating intramyocardial injector, comprising a syringe 1, a needle plug 2, a needle head 7, an injector composed of an adjustment ring 3 and an outer sleeve 5, the needle plug 2 in the syringe 1, and the front end of the needle plug The protruding protrusion 6 is used to reduce the dead space of the syringe; the needle 7 and the syringe 1 are fixedly connected through the thread 8; The locking screw 4 is installed on the ring 3; the outer sleeve 5 is inserted into the syringe 1 to the adjustment ring 3 from the direction of the needle 7, and the needle 7 passes through the rubber pad 9 at the front end of the outer sleeve 5, and the length of the exposed needle part can be pierced. The length of the ventricular muscle.

Implementation method of the present utility model:

(1) After thoracotomy, cut and suspend the pericardium to expose the ventricular muscle at the intended injection site;

(2) According to the size of the heart and the thickness of the ventricular muscle, determine the length c of the needle that needs to be inserted into the ventricular muscle;

(3) Move the adjustment ring 3 along the outer wall of the syringe 1 to change its position, so that the front end of the adjustment ring 3 is aligned with the scale (c) on the outer wall of the syringe 1 [the scale c is the length of the exposed needle that can penetrate into the ventricular muscle, c =a-b (a is the distance from the needle tip to the front end of the adjustment ring, b is the total length of the outer casing)], tighten the screw 4 on the adjustment ring 3 to fix the adjustment ring 3;

(4) Use the injector not connected to the needle 7 to extract the required injection (such as cell suspension, etc.), connect the needle 7 and tighten the interface thread 8;

(5) Put the outer sleeve 5 into the injector from the direction of the needle 7, make the injector needle 7 pass through the rubber pad 9 at the front end of the outer sleeve 5, the end of the outer sleeve 5 is against the adjustment ring 3, and the exposed needle part at the front end of the outer sleeve 5 is is the length c that can penetrate into the ventricular muscle;

(6) Pierce the exposed needle 7 into the pulsating ventricular muscle at the site to be injected, and after withdrawing the blood, fix the overtube 5 with one hand, and push the needle plug 2 with the other hand, so that the injection enters the ventricular muscle from the syringe 1;

(7) After the injection is completed, keep the overtube 5 still fixed with one hand, pull out the overtube 5 simultaneously with the injector and the needle 7 with the other hand, continue to fix the overtube 5 and apply moderate pressure, so that the rubber pad 9 at the front end presses the ventricular wall by about 0.5 After 1 minute, the outer sleeve 5 is removed, and the entire injection process ends.

Claims (2)

1. an adjustable pulsatile myocardial internal injector comprises syringe (1), pintle (2), and syringe needle (7), adjustable ring (3), trocar sheath (5) is characterized in that:

1) syringe (1) is outer adjustable ring (3), and can slide along needle cylinder wall, and adjustable ring (3) is provided with lock screw (4);

2) syringe (1) is outer trocar sheath (5), and front end has rubber blanket (9);

3) syringe needle (7) is fixing with being connected by screw thread (8) of syringe (1);

4) piston nose of pintle (2) is for stretching into formula projection (6);

5) on syringe (1) wall double scale labelling is arranged, i.e. volume markings and length scale;

6) the long 3cm of syringe needle (7), syringe needle (7) bore 0.5～1.0mm.

2. adjustable pulsatile myocardial internal injector according to claim 1 is characterized in that, described syringe needle (7) passes trocar sheath rubber blanket (9), needle length (the c)=a-b of ventricular muscles is thrust in its adjusting, wherein, a is the distance of needle point to adjustable ring (3) front end, and b is trocar sheath (a 5) total length.

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