CN1943751A - A health-protective pharmaceutical for activating and improving intellect and its preparation method - Google Patents
A health-protective pharmaceutical for activating and improving intellect and its preparation method Download PDFInfo
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Abstract
A brain activating and intelligence-promoting health care medicament and preparation method, selecting radix notoginseng, radix angelicae sinensis , radix paeoniae rubra, cortex moutan, fructus alpiniae oxyphyllae, radix polygalae, day lily ,semen juglandis, semen cuscutae, semen ziziphi spinosae, herba menthae, bulbus allii, semen platycladi, radix glycyrrhizae ,ginkgo extract, alpha-lipoic acid, phosphatidyl choline, pyroglutamic acid ester as raw manufacturing materials. The present invention can increase cerebral blood flow, add nutrient substances needed by cerebral memory, inoxidize and remove harmful free radicals, promote metabolism, increase the permeabilitythe membrane of the cranial nerves and presynapses and postsynapses supplemented with mind- tranquilizing and intelligence-promoting Chinese traditional medicine, make nutrient substances easy to pass through the blood-brain barrier, supplement oxygen , nutrient substances and energy to the brain on every side, has the noticeable effect of enhancing the activity of brain cells thereby exert the brain's potential, activate the brain, promoting intelligence and anti-fatigue. It mainly applied to increase the cerebral blood flow, add cerebral energy, and relieve the brain fatigue, in order to achieve significant increase in memory, enhancement of intelligence of middle school students or pupils and young adults.
Description
(1) technical field
The present invention relates to a kind of brain alive, brain-strengthening, Fructus Alpiniae Oxyphyllae, antifatigue health medicine and preparation method thereof, belong to the Chinese medicine health-care technical field.
(2) background technology
People's brain is made up of 140～15,000,000,000 neurocytes.The neurocyte of brain is constantly division renewal unlike other histiocyte of human body, just no longer division of the neurocyte of brain behind baby due, cell itself can be aging and dead gradually, 1000 nerve cell deaths are arranged average every day approximately, during by 70 years old, it is about 2% that brain cell can reduce, and the man at an advanced age reduces 3% approximately.
The potentiality of brain are very big, people's all one's life, but the brain information stored is equivalent to 50 times of American National library collection amount.People's the actual in life brain cell of using up that makes is less than one of total percentage, even the most genius scientist has also only employed few part of brain cell lifetime.Therefore, do not need to worry, but note slowing down the decline of brain function, and it is still necessary to give full play to the potentiality of brain for the minimizing of neurocyte.
How just can give full play to the potentiality of brain? scientific research proves: as long as make brain cell obtain more oxygen and nutrient energy, remove the harmful free radical of brain cell, promote metabolism to quicken, thereby just can strengthen the potentiality of the mobility performance brain of brain cell.
Existing Fructus Alpiniae Oxyphyllae product is more, aspect the treatment cardiovascular and cerebrovascular disease, Western medicine not as antibiolics in the absolute advantages of treatment aspect the infectious disease, Chinese medicine then can be taken charge of a department, and becomes the Chinese medicine cardiovascular and cerebrovascular vessel medicine market of getting the upper hand of.China Patent No. 02142258.3 discloses a kind of brain active function material of preventing and treating encephalopathy and Fructus Alpiniae Oxyphyllae and preparation method thereof, it is that the extract of the shell (comprising fruit stem) with Lignum Xanthoceratis is a brain active function material, be used for making control brain aging and cerebrovascular, promote intelligence, the treatment nocturia, the enuresis, incontinence, frequent micturition and retarded, senile dementia, Parkinson's disease etc. are because brain function is unsound or the health product or the medicine of the caused disease of obstacle.Other has China Patent No. 03111964.6 to disclose a kind of medicine for the treatment of the vascular dementia disease and preparation method thereof, and it is made by Rhizoma Chuanxiong, Herba Epimedii, Folium Ginkgo, Radix Angelicae Sinensis, is used for the treatment of vascular dementia.Through the Chinese patent retrieval, do not find and the akin bibliographical information of the technical program.
(3) summary of the invention
Purpose of the present invention aims to provide the big cerebral blood flow of a kind of increase, replenishes the brain energy, removes brain fag rapidly, reaches remarkable increase memory, improves the IQ effect; Can be used for again treating and prevention of brain is aging and cerebrovascular, senile dementia, Parkinson's disease etc. because brain function is unsound or health medicine of the caused disease of obstacle and preparation method thereof.
The key component of medicine of the present invention and percentage by weight are:
Chinese herbal medicine extract 55～70%;
Chinese herbal medicine extracting volatile oil 0.3～5%
Semen Ginkgo extrac 5～20%
Phosphatidylcholine 0.3～5%
Alpha-lipoic acid 0.3～5%
Perilla oil 0.3～5%
Pyroglutamic acid ester 0.3～5%
Chinese herbal medicine extract and extract volatile oil wherein is by weight percentage:
Radix Notoginseng 4～25% Radix Angelicae Sinensis 4～25%
Radix Paeoniae Rubra 4～25% Cortex Moutans 3～20%
Fructus Alpiniae Oxyphyllae 4～25% Radix Polygalaes 3～20%
Semen Juglandis 4～25% Semen Cuscutae 3～20%
Semen Ziziphi Spinosae 3～20% Herba Menthaes 3～20%
Datlily 3～20% Bulbus Alliis: 2～15%
Semen Platycladi 3～20% Radix Glycyrrhizaes (processed with honey) 2～15%
The extraction process of Chinese herbal medicine extract of the present invention and extraction volatile oil may further comprise the steps:
(1) Radix Angelicae Sinensis, Cortex Moutan, Herba Menthae, 4 kinds of Chinese herbal medicine of Bulbus Allii are taken by weighing and be ground into coarse powder in proportion, add 5 times of water gagings, be heated to little boiling 6 hours, extract collection and obtain Chinese herbal medicine volatile oil; Medicinal residues and water give over to next step and extract usefulness;
(2) Radix Notoginseng, Radix Paeoniae Rubra, Fructus Alpiniae Oxyphyllae, Radix Polygalae, Semen Juglandis, Semen Cuscutae, Semen Ziziphi Spinosae, Datlily, Semen Platycladi, 10 kinds of Chinese herbal medicine of Radix Glycyrrhizae are taken by weighing and are ground into coarse powder in proportion, add in the ultrasound wave Chinese herbal medicine extracting machine together with above-mentioned medicinal residues and the water that has extracted volatile oil, with 60% ethanol ultrasonic extraction secondary, merge extractive liquid,, reclaim ethanol and be condensed into dry extract, obtain Chinese herbal medicine extract.
The present invention sets about from the mobility that strengthens brain cell, the potentiality of performance brain, reaches supplemental oxygen and nutrient energy by utilizing the big cerebral blood flows of increase such as Radix Notoginseng, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Cortex Moutan, Semen Ginkgo; Be aided with Fructus Alpiniae Oxyphyllae, Radix Polygalae, Semen Juglandis, Semen Cuscutae, Semen Ziziphi Spinosae, Herba Menthae, Datlily, Bulbus Allii, Semen Platycladi, the Radix Glycyrrhizae Fructus Alpiniae Oxyphyllae effect of calming the nerves simultaneously; Utilize nutrient substance phosphatidylcholine, the pyroglutamic acid ester of promoting the brain memory function; Utilize the alpha-lipoic acid that the brain anti-oxidation function is maximum and activity is the strongest to remove harmful free radical, promote metabolism; Utilize perilla oil, phosphatidylcholine that the permeability of cerebral nerve film, presynaptic caudacoria is improved, make nutrient substance be easy to pass through blood brain barrier, from comprehensive additional brain oxygen and nutrient energy, absorbed by cerebral tissue fast, make the neurotransmission path unimpeded, improve the neural reflex ability, people's language ability of thinking, respond, memory are improved, thereby reach the potentiality of the mobility performance brain that strengthens brain cell.
Advantage of the present invention is that brain Fructus Alpiniae Oxyphyllae alive, resisting fatigue effect are obvious.The present invention is by theory of Chinese medical science, on the basis of " benefit ", reuse invigorate blood circulation, sensible product, by improving blood circulation, increasing big cerebral blood flow, its effect is obviously improved.It mainly is applicable to increases students in middle and primary schools, between twenty and fifty big cerebral blood flow, replenish the brain energy, removes brain fag rapidly, the effect that reach remarkable increase memory, improves IQ; Can be used for the aging and cerebrovascular of treatment and prevention of brain, senile dementia, Parkinson's disease etc. again because the unsound or caused disease of obstacle of brain function.
(4) specific embodiment
Embodiment one:
(1) take by weighing component:
Radix Notoginseng 15% Radix Angelicae Sinensis 12%
Radix Paeoniae Rubra 8% Cortex Moutan 8%
Fructus Alpiniae Oxyphyllae 8% Radix Polygalae 8%
Semen Juglandis 8% Semen Cuscutae 5%
Semen Ziziphi Spinosae 3% Herba Menthae 3%
Datlily 3% Bulbus Allii: 2%
Semen Platycladi 3% Radix Glycyrrhizae (processed with honey) 2%
Semen Ginkgo extrac 5%
Phosphatidylcholine 2%
Alpha-lipoic acid 1%
Perilla oil 0.5%
Pyroglutamic acid ester 3.5%
(2) Radix Angelicae Sinensis, Cortex Moutan, Herba Menthae, 4 kinds of Chinese herbal medicine of Bulbus Allii are taken by weighing and be ground into coarse powder in proportion, add 5 times of water gagings, be heated to little boiling 6 hours, extract collection and obtain Chinese herbal medicine volatile oil; Medicinal residues and water give over to next step and extract usefulness.
(3) Radix Notoginseng, Radix Paeoniae Rubra, Fructus Alpiniae Oxyphyllae, Radix Polygalae, Semen Juglandis, Semen Cuscutae, Semen Ziziphi Spinosae, Datlily, Semen Platycladi, 10 kinds of Chinese herbal medicine of Radix Glycyrrhizae are taken by weighing and are ground into coarse powder in proportion, add in the ultrasound wave Chinese herbal medicine extracting machine together with above-mentioned medicinal residues and the water that has extracted volatile oil, with 60% ethanol ultrasonic extraction secondary, merge extractive liquid,, reclaim ethanol and be condensed into dry extract, obtain Chinese herbal medicine extract.
(4) capsule, preparation of soft capsule: with above-mentioned (2), the volatile oil of (3) Chinese herbal medicine extracting, extract extractum, add Semen Ginkgo extrac, phosphatidylcholine, perilla oil, pyroglutamic acid ester and an amount of adjuvant mix homogeneously, capsule or soft capsule are made in packing.
Embodiment two:
In volatile oil that said herbal medicine is extracted and extract, add following Semen Ginkgo extrac, phosphatidylcholine, perilla oil, pyroglutamic acid ester by weight percentage:
Chinese herbal medicine extract 55～65%;
Chinese herbal medicine extracting volatile oil 0.5～5%
Semen Ginkgo extrac 8～20%
Phosphatidylcholine 0.5～5%
Alpha-lipoic acid 0.5～5%
Perilla oil 0.5～5%
Pyroglutamic acid ester 0.5～5%
With above-mentioned health care medicine active substance powder, add suitable adjuvant and can make oral drug or health product such as tablet, capsule, soft capsule, pill, drop pill, buccal tablet, electuary and fluid infusion.
Embodiment three:
Chinese herbal medicine extract and extraction volatile oil are by weight percentage:
Radix Notoginseng 5～20% Radix Angelicae Sinensis 5～20%
Radix Paeoniae Rubra 5～20% Cortex Moutans 4～15%
Fructus Alpiniae Oxyphyllae 5～20% Radix Polygalaes 4～15%
Semen Juglandis 5～20% Semen Cuscutae 4～15%
Semen Ziziphi Spinosae 4～15% Herba Menthaes 4～15%
Datlily 4～15% Bulbus Alliis: 3～10%
Semen Platycladi 4～15% Radix Glycyrrhizaes (processed with honey) 3～10%
It does not state the same embodiment of part.
Claims (5)
1. brain brain-tonifying healthcare medicine alive is characterized in that its key component and percentage by weight are:
Chinese herbal medicine extract 55～70%;
Chinese herbal medicine extracting volatile oil 0.3～5%
Semen Ginkgo extrac 5～20%
Phosphatidylcholine 0.3～5%
Alpha-lipoic acid 0.3～5%
Perilla oil 0.3～5%
Pyroglutamic acid ester 0.3～5%
2. brain brain-tonifying healthcare medicine alive according to claim 1 is characterized in that Chinese herbal medicine extract and extracts volatile oil, is by weight percentage:
Radix Notoginseng 4～25% Radix Angelicae Sinensis 4～25%
Radix Paeoniae Rubra 4～25% Cortex Moutans 3～20%
Fructus Alpiniae Oxyphyllae 4～25% Radix Polygalaes 3～20%
Semen Juglandis 4～25% Semen Cuscutae 3～20%
Semen Ziziphi Spinosae 3～20% Herba Menthaes 3～20%
Datlily 3～20% Bulbus Alliis: 2～15%
Semen Platycladi 3～20% Radix Glycyrrhizaes (processed with honey) 2～15%
3. brain brain-tonifying healthcare medicine alive according to claim 2 is characterized in that Chinese herbal medicine extract and extracts volatile oil, is by weight percentage:
Radix Notoginseng 5～20% Radix Angelicae Sinensis 5～20%
Radix Paeoniae Rubra 5～20% Cortex Moutans 4～15%
Fructus Alpiniae Oxyphyllae 5～20% Radix Polygalaes 4～15%
Semen Juglandis 5～20% Semen Cuscutae 4～15%
Semen Ziziphi Spinosae 4～15% Herba Menthaes 4～15%
Datlily 4～15% Bulbus Alliis: 3～10%
Semen Platycladi 4～15% Radix Glycyrrhizaes (processed with honey) 3～10%
4. the preparation method of brain brain-tonifying healthcare medicine alive according to claim 1 is characterized in that its Chinese herbal medicine extract and extracts the extraction process of volatile oil, may further comprise the steps:
(1) Radix Angelicae Sinensis, Cortex Moutan, Herba Menthae, 4 kinds of Chinese herbal medicine of Bulbus Allii are taken by weighing and be ground into coarse powder in proportion, add 5 times of water gagings, be heated to little boiling 6 hours, extract collection and obtain Chinese herbal medicine volatile oil; Medicinal residues and water give over to next step and extract usefulness;
(2) Radix Notoginseng, Radix Paeoniae Rubra, Fructus Alpiniae Oxyphyllae, Radix Polygalae, Semen Juglandis, Semen Cuscutae, Semen Ziziphi Spinosae, Datlily, Semen Platycladi, 10 kinds of Chinese herbal medicine of Radix Glycyrrhizae are taken by weighing and are ground into coarse powder in proportion, add in the ultrasound wave Chinese herbal medicine extracting machine together with above-mentioned medicinal residues and the water that has extracted volatile oil, with 60% ethanol ultrasonic extraction secondary, merge extractive liquid,, reclaim ethanol and be condensed into dry extract, obtain Chinese herbal medicine extract.
5. the preparation method of brain brain-tonifying healthcare medicine alive according to claim 4, it is characterized in that this health medicine active substance powder, add suitable adjuvant and make tablet, capsule, soft capsule, pill, drop pill, buccal tablet, electuary or fluid infusion oral drug or health product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200610122790 CN1943751A (en) | 2006-10-10 | 2006-10-10 | A health-protective pharmaceutical for activating and improving intellect and its preparation method |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102512506A (en) * | 2012-01-01 | 2012-06-27 | 山东大学威海分校 | Compound acanthopanax root preparation capable of improving activity of superoxide dismutase |
| CN103547174A (en) * | 2011-04-29 | 2014-01-29 | 马可·齐波利 | Foodstuffs, especially beverages intended for human consumption |
| CN104524160A (en) * | 2014-12-10 | 2015-04-22 | 常州诺瑞格纳米科技有限公司 | Brain-strengthening and blood circulation-promoting health care product |
| CN106074577A (en) * | 2016-06-30 | 2016-11-09 | 重庆帅旭科技发展有限公司 | For improving functional type alimentation composition and the application thereof of memory |
| CN107334843A (en) * | 2017-06-12 | 2017-11-10 | 芜湖福民生物药业股份有限公司 | Chinese medicine preparation containing phosphatidyl choline and preparation method thereof |
| CN108813453A (en) * | 2018-05-23 | 2018-11-16 | 青岛大学 | A kind of edible composition for preventing and treating Parkinson's disease |
| CN108813628A (en) * | 2018-05-23 | 2018-11-16 | 青岛大学 | A kind of preparation method preventing and treating Parkinson's disease edible composition |
-
2006
- 2006-10-10 CN CN 200610122790 patent/CN1943751A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103547174A (en) * | 2011-04-29 | 2014-01-29 | 马可·齐波利 | Foodstuffs, especially beverages intended for human consumption |
| CN102512506A (en) * | 2012-01-01 | 2012-06-27 | 山东大学威海分校 | Compound acanthopanax root preparation capable of improving activity of superoxide dismutase |
| CN104524160A (en) * | 2014-12-10 | 2015-04-22 | 常州诺瑞格纳米科技有限公司 | Brain-strengthening and blood circulation-promoting health care product |
| CN106074577A (en) * | 2016-06-30 | 2016-11-09 | 重庆帅旭科技发展有限公司 | For improving functional type alimentation composition and the application thereof of memory |
| CN107334843A (en) * | 2017-06-12 | 2017-11-10 | 芜湖福民生物药业股份有限公司 | Chinese medicine preparation containing phosphatidyl choline and preparation method thereof |
| CN108813453A (en) * | 2018-05-23 | 2018-11-16 | 青岛大学 | A kind of edible composition for preventing and treating Parkinson's disease |
| CN108813628A (en) * | 2018-05-23 | 2018-11-16 | 青岛大学 | A kind of preparation method preventing and treating Parkinson's disease edible composition |
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