CN1823989A - Composition for treating gynecopathy and its preparation method - Google Patents

Abstract

A composite Chinese medicine for treating gynopathy and its preparing process are disclosed.

Description

The gynopathic composition and method of making the same of a kind of treatment

The present invention relates to a kind of Chinese medicine composition, is the gynopathic Chinese medicine composition of treatment specifically, the invention still further relates to the preparation technology of said composition.

According to the investigation of The World Health Organization (WHO), there is Chinese women more than 70% to suffer from various degree gynaecopathia, married women's gynaecopathia prevalence is more up to more than 90%.The women is 100% gynaecopathia of suffering from various degree almost in life, and wherein gynecological inflammation such as pelvic inflammatory disease, endometritis and cervicitis etc. are women's commonly encountered diseases, account for the out-patient's of gynecological about 89%.Menoxenia in addition, dysmenorrhea also are women's commonly encountered diseases and frequently-occurring diseases.

Leukorrheal diseases are one of commonly encountered diseases, frequently-occurring disease of women, have the saying of " ten woman, nine bands ", and primary disease has that the course of disease is tediously long, the difficult characteristics that heal of delay, has brought many miseries for numerous women.Its pathogenic factor, when modern medicine is thought childbirth or miscarriage, premature rupture of fetal membrane, or the fetal membrane Placenta Hominis is residual, or the intrauterine surgical sterilization is not tight, or unclean woman inspection, or reason such as sexual intercourse in menstrual period, cause courses of infection, make endometrium and adnexa even whole pelvic congestion edema, severe patient can suppurate, and is extensively downright bad.Maximum with damp-heat leukorrhagia, symptom feature is a leukorrhagia amount showed increased, and yellow skin, gas are smelly; Though or amount is few, makings is stench unusually, or with whole body or local symptom.The traditional Chinese medical science roughly is divided into primary disease and insufficiency of the spleenly wet gather into band and become to be with two classes with the instability of kidney-QI of suffering from a deficiency of the kidney.Women's menorrhagia, hold concurrently insufficiency of vital energy and blood card of the damp invasion of lower energizer of menostaxis is more common in pelvic inflammatory disease, endometritis, the cervicitis patient of doctor trained in Western medicine, pelvic inflammatory disease is female sex organ (uterus, fallopian tube, ovary) and connective tissue and pelvic peritoneum on every side, the general designation that be inflamed by bacteria attack is one of commonly encountered disease.Pelvic inflammatory disease is basin device inflammation again, can a place or a few place fall ill simultaneously.Because fallopian tube, ovary general designation adnexa, and the fallopian tube inflammation involves " neighbour " ovary often, therefore, the title of adnexitis arranged again, and adnexitis is included among the pelvic inflammatory disease, and sickness rate is the highest.The pathogen that causes pelvic inflammatory disease is staphylococcus, escherichia coli, streptococcus, anaerobe and the pathogen that spreads through sex intercourse such as herpesvirus, chlamydia trachomatis and mycoplasma etc.Pelvic inflammatory disease can be divided into acute pelvic inflammatory disease and chronic pelvic inflammatory disease.Endometritis is the endometrial inflammation of uterus body, can influence myometrium when inflammation is developed to serious stage, becomes myometritis, and this is the extension of endometritis, is common a kind of genital organ disease, also is to cause one of infertile major reason.Endometritis divides acute and chronic two kinds.Cervicitis is particularly a kind of commonly encountered diseases of middle-aged women of childbearing age women, divides two kinds of acute and chronic cervicitiss.How because of childbirth, miscarriage or surgical injury cervix uteri, pathogen is invaded and is infected.Clinical more common with chronic cervicitis, the performance of many NAIs process.The morbidity of chronic cervicitis and official's neck cancer has certain relation, and according to the study, it is 0.75% that the cervical cancer incidence rate of cervical erosion is arranged, and is significantly higher than no cervical erosion person.

Therefore, the active treatment cervicitis is to the significance that has of prevention cervical cancer.

Summary of the invention

Purpose of the present invention just provides a kind of treatment gynaecopathia Chinese medicine composition of determined curative effect.

Another object of the present invention provides the preparation method of this Chinese medicine composition.

Chinese medicine composition of the present invention is made up of active component or pharmaceutically acceptable carrier, and preferred active component is to be made by following raw materials by weight percent:

Radix Flemingiae Philippinensis 11.2% Radix Rosae Laevigatae 16.9% Caulis Mahoniae 16.9% Caulis Spatholobi 16.9% Fructus Zanthoxyli Dissiti 9.5% Herba Andrographis 9.5% Radix Codonopsis 9.5% Radix Angelicae Sinensis 9.5%

The present invention is made up of medicines such as Radix Rosae Laevigatae, Radix Flemingiae Philippinensis, Caulis Mahoniae, Herba Andrographis, Fructus Zanthoxyli Dissiti, Radix Angelicae Sinensis, Caulis Spatholobi, Radix Codonopsis, and Radix Rosae Laevigatae clearing away heat and eliminating dampness, controlling nocturnal emission with astringent drugs reducing urination are principal agent in the side; The detoxifcation of Radix Flemingiae Philippinensis clearing away heat-damp and promoting diuresis; The Caulis Mahoniae clearing away heat and cooling blood; The Herba Andrographis heat-clearing and toxic substances removing; The Fructus Zanthoxyli Dissiti promoting blood circulation and detoxication, reducing swelling and alleviating pain, promoting of the circulation of QI and removing the obstruction in the collaterals; Chinese Angelica blood replonishing is invigorated blood circulation, and relaxing muscles and tendons and activating QI and blood in the collateral is transferred to dash and appointed, and ends stomachache, is accessory drugs altogether; The Caulis Spatholobi promoting the circulation of blood of enriching blood; The Radix Codonopsis invigorating the spleen and replenishing QI, invigorating the spleen to clear away damp pathogen is adjuvant drug altogether.All medicines share, and QI and blood is ruled together, and giving consideration to both the incidental and fundamental is mended combination clearly, and detoxification and removing stasis is played the clearing away heat-damp and promoting diuresis detoxifcation altogether with executing, strong waist collateral dredging, the effect of vigorate qi and replenish the blood.Thereby make QI and blood prosperous, clearing moist heat, stasis of blood poison goes, and all diseases are from removing.Modern pharmacological research shows that Radix Rosae Laevigatae contains abundant tannin, and good astriction is arranged, also antibiotic, the antivirus action of tool; Effects such as that Caulis Mahoniae has is antibiotic, excited heart; Radix Flemingiae Philippinensis, the equal tool antiinflammatory of Fructus Zanthoxyli Dissiti, blood vessel dilating, improve the blood circulation effect; That Herba Andrographis has is antibiotic, antiinflammatory, the effect of enhancing body defense function; Radix Angelicae Sinensis can activate immunity, anti-anemia, blood vessel dilating, improve blood fortune, to the uterus have excited with suppress the dual regulation effect; Caulis Spatholobi can be enriched blood, excited uterus; Radix Codonopsis has enhancing human body immunity, and stimulating central nervous system improves the hemoglobin effect.Can act on whole body and urinary system, reproductive system entirely, the both adjustable body function of giving sb. a hard time can be improved periphery and local blood fortune again, and the bladder and the function of back urethra are coordinated, and clinical symptoms is eliminated or improves.

The present invention treats leukorrheal diseases and has advantages such as leukorrhagia stopping is rapid, course of disease shortening.The damp-heat leukorrhagia treatment should be with the clearing away heat-damp and promoting diuresis leukorrhagia stopping, and holding concurrently with the spleen invigorating eliminating dampness by diuresis is rule of treatment.

The preparation technology that the present invention treats active component in the gynaecopathia compositions is as follows: Herba Andrographis, Radix Angelicae Sinensis, Radix Codonopsis powder are broken into fine powder, sieve, mixing, all the other Radix Flemingiae Philippinensiss, Radix Rosae Laevigatae, Caulis Mahoniae, Caulis Spatholobi, the Fructus Zanthoxyli Dissiti five tastes decoct with water secondary, each 3 hours, collecting decoction filters, and filtrate is concentrated into the clear paste that relative density is 1.08 (60 ℃ of heat are surveyed).Qinghuo reagent adds above-mentioned fine powder and an amount of Icing Sugar, dextrin, hydroxypropyl first fiber rope makes into granule with correctives, drying; Or qinghuo reagent adds above-mentioned fine powder and an amount of dextrin, hypromellose and correctives makes into granule, drying; Sieve, promptly.

The active component that the present invention treats gynecological and compositions can be prepared into various pharmaceutically acceptable dosage forms with pharmaceutically acceptable carrier, the preferred oral form of administration, as solid dosage forms tablet, granule, capsule etc., liquid preparation such as oral liquid, decoction, medicated wine, mixture etc.The preferred particulates agent.

The present invention treats the gynaecopathia compositions and has removing damp-heat, benefiting vital QI and blood.Be used for leukorrheal diseases, damp invasion of lower energizer, insufficiency of vital energy and blood disease.Pelvic inflammatory disease, endometritis, cervicitis are seen above-mentioned patient.

Accompanying drawing: be the process chart that proposes according to the present invention.

Concrete embodiment

Embodiment 1

Take by weighing following raw materials in weight: Radix Flemingiae Philippinensis 117.8g, Radix Rosae Laevigatae 177.8g, Caulis Mahoniae 177.8g, Caulis Spatholobi 177.8g, Fructus Zanthoxyli Dissiti 100g, Herba Andrographis 100g, Radix Codonopsis 100g, Radix Angelicae Sinensis 100g, more than eight the flavor, Herba Andrographis, Radix Angelicae Sinensis, Radix Codonopsis powder are broken into fine powder, cross 120 mesh sieves, mixing, all the other five tastes decoct with water secondary, each 3 hours, collecting decoction filters, and filtrate is concentrated into the clear paste that relative density is 1.20-1.25 (60 ℃ of heat is surveyed).Qinghuo reagent adds above-mentioned fine powder and an amount of Icing Sugar, dextrin, hypromellose and correctives makes into granule, and drying is made 1000g; Or qinghuo reagent adds above-mentioned fine powder and an amount of dextrin, hypromellose and correctives makes into granule, and drying is made 500g (Sugarless type); Sieve, promptly.

Claims (3)

1, treat gynopathic composition and method of making the same, it is characterized in that: with the Chinese medicine material, Radix Flemingiae Philippinensis 117.8g, Radix Rosae Laevigatae 177.8g, Caulis Mahoniae 177.8g, Caulis Spatholobi 177.8g, Fructus Zanthoxyli Dissiti 100g, Herba Andrographis 100g, Radix Codonopsis 100g, Radix Angelicae Sinensis 100g.(ratio is: Radix Flemingiae Philippinensis 11.2% Radix Rosae Laevigatae 16.9% Caulis Mahoniae 16.9% Caulis Spatholobi 16.9% Fructus Zanthoxyli Dissiti 9.5% Herba Andrographis 9.5% Radix Codonopsis 9.5% Radix Angelicae Sinensis 9.5%)

2, according to claims 1, it is characterized in that Herba Andrographis, Radix Angelicae Sinensis, Radix Codonopsis powder are broken into fine powder, cross 120 mesh sieves, mixing, all the other Radix Flemingiae Philippinensiss, Radix Rosae Laevigatae, Caulis Mahoniae, Caulis Spatholobi, the Fructus Zanthoxyli Dissiti five tastes decoct with water secondary, and each 3 hours, collecting decoction, filter, filtrate is concentrated into the clear paste that relative density is 1.20-1.25 (60 ℃ of heat is surveyed).

3, according to claims 2, it is characterized in that qinghuo reagent adds above-mentioned fine powder and an amount of Icing Sugar, dextrin, hypromellose and correctives makes into granule, drying is made 1000g; Or qinghuo reagent adds above-mentioned fine powder and an amount of dextrin, hypromellose and correctives makes into granule, and drying is made 500g (Sugarless type); Sieve, promptly.

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