CN1679661A - Medicine for treating female mazoplasia and preparation thereof - Google Patents

Abstract

A Chinese medicine 'Rubao capsule' or 'Rubao bra' for treating mastoplasia of woman is prepared from 11 Chinese-medicinal materials including prunella spike, oyster shell, scrophularia root, asparagus root, etc through proportional mixing, grinding, sieving, disinfecting and high-pressure shaping.

Description

A kind of medicine for the treatment of female mammary gland proliferation and preparation method thereof

One, technical field

The present invention relates to the preparation method of the medicine of a kind of treatment and prevention female mammary gland proliferation.

Two, background technology

The hyperplasia of mammary glands disease belongs to the dialectical category of motherland's traditional medicine " nodules of the breast ", and it is many because of damaged by excess of seven emotions, depression of liver-QI, QI-blood circulation are smooth, phlegm-damp is tied mutually, stagnating is disease to fall ill.Cardinal symptom be women oneself lay one's hand on and one-sided or bilateral breast in size, tuberosity that how many degree depths are different are arranged.Also there are many women oneself not know that the state of an illness needs the health check-up generaI investigation just to learn.Most women occur together before menstrual onset distending pain of the breast, fidgety, sx or the disappearance after row of mood, mastalgia slightly or does not not bitterly have periodically at ordinary times, good sending out in giving birth to the high age bracket of vigorous hormonal readiness in 20-40 year.This disease often influences women's physical and mental health and life and work as if untimely healing, the tendency that with the passing of time oriented bad disease (breast carcinoma) transforms.To the prevention of cyclomastopathy, medicament categories is many, but only limits to oral medication at present.

Three, summary of the invention

The purpose of this invention is to provide a kind of Orally taken and externally and develop simultaneously, the curative effect of working along both lines is reliable, and adaptability is strong, is specifically designed to the pure Chinese herbal medicine of treatment and prevention cyclomastopathy.

Another object of the present invention provides the preparation method of treatment cyclomastopathy medicine.Contain herbal raw material ratio prescriptions in accordance with regulations such as Spica Prunellae, Concha Ostreae, Radix Scrophulariae, Radix Asparagi, Bulbus Fritillariae Thunbergii, Radix Curcumae, Semen Vaccariae, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Cyperi, corydalis tuber in the Chinese herb medicine of the present invention's treatment and prevention cyclomastopathy, the weight proportion of described each composition following (unit is gram)

Fructus Trichosanthis 30-45g rhizoma sparganic 15-20g Fructus Toosendan 20-30g

Rhizoma Chuanxiong 20-30g Rhizoma Curcumae 15-20g Caulis Spatholobi 30-40g

Flos Carthami 10-15g Radix Curcumae 20-30g Bulbus Fritillariae Thunbergii 30-60g

Semen Vaccariae 30-40g Radix Platycodonis 10-15g Spica Prunellae 60-80g

Rhizoma Cyperi 15-20g Even sticks up 15-30g Herba Taraxaci 30-45g

Rhizoma Dioscoreae Bulbiferae 10-20g Concha Ostreae 40-60g Scorpio 20-30g

The red Radix Paeoniae Alba 30-40g of corydalis tuber 20-30g Radix Asparagi 30-40g

Radix Scrophulariae 60-80g Fructus Aurantii 30-40g

The preparation method that the present invention relates to a kind of treatment and prevention female mammary gland proliferation medicine is to incapsulate and make the medicine cover after the said herbal medicine thing is ground not, sieves, mixes, sterilizes to form by quantitative package.

Medicine of the present invention is from traditional Chinese medical science viewpoint, thinks that the pathogenic factor of cyclomastopathy is except with damaged by excess of seven emotions, depression of liver-QI, QI-blood circulation are smooth, phlegm-damp is tied mutually, stagnate to sick relevant, also relevant with women's hormone in vivo off-leveling simultaneously.At 20-40 year period of duration women's pathogenic factor and disease performance, choose have hard masses softening and resolving, the Chinese herbal medicine of activating QI to eliminate phlegm, removing obstruction in the collateral to relieve pain, the horizontal effect of adjusting women hormone in vivo, rigorous prescription.

The performance that relates to Chinese herbal medicine in the pharmaceutical formulation of the present invention is: Spica Prunellae, Fructus Trichosanthis, Bulbus Fritillariae Thunbergii, Fructus Toosendan hard masses softening and resolving reduce phlegm, and going stagnates is principal agent, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Dioscoreae Bulbiferae, Caulis Spatholobi, the red Radix Paeoniae Alba, corydalis tuber, Scorpio, it is up for the pharmacy of holding concurrently, Radix Platycodonis, Semen Vaccariae, Rhizoma Chuanxiong medicine carrying that removing obstruction in the collateral to relieve pain is adjuvant, Radix Asparagi, Radix Ophiopogonis, Radix Curcumae, Herba Taraxaci diminishing inflammation and resolving masses, and through sick institute mediation lactiferous ducts is for drawing and medicine.The mutual compatibility of said medicine through strictness processing fill capsule and medicine cover Orally taken and externally, has the effect of hard masses softening and resolving, activating QI to eliminate phlegm, removing obstruction in the collateral to relieve pain, adjusting women hormone in vivo level.

Using method:

A: Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) was a course of treatment in 30-60 days.

B: newborn precious medicine cover: circular textile sheet, diameter 8-10cm, weight 20-30g are put into each one of two breast brassiere, and 15-30 days is a course of treatment.

The advantage of drug use of the present invention is: external application develops simultaneously, and the curative effect of working along both lines is reliable, and adaptability is strong, is specifically designed to the pure Chinese herbal medicine of treatment and prevention cyclomastopathy.

In order to prove that medicine of the present invention has the effect of treatment cyclomastopathy, the cyclomastopathy patient of the bright Yong of selection of clinical 120 example diagnosis is divided into treatment group and each 60 example of matched group at random by patient's wish.(the 1-3 month) treatment group gives Rubao capsule three times on the one in the treatment time of regulation, and a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) adds with newborn precious medicine cover and puts into each one of two breast brassiere, and 15-30 days is a course of treatment.

Efficacy assessment standard: cure, breast nodule is subdued mastalgia and is disappeared.Produce effects, breast nodule does not disappear, but mastalgia disappears.Invalid, breast nodule and pain ditto do not have improvement.

Experimental result: 60 routine total effective rates 86.6% are organized in treatment, cure 31 examples, 21 examples that take a turn for the better, and treatment time is 30-60 days, matched group 60 examples, total effective rate 60.5% is cured 27 examples, and 8 examples take a turn for the better.Two groups of total effects significant differences, treatment group clinical effectiveness is apparently higher than matched group.Follow up a case by regular visits to nontoxic pair of effect and untoward reaction.

Medical record is given an example:

1, Lin: Altay City paper mill, 39 years old Chinese Xinjiang of women, accounting.April 27 calendar year 2001 because of conscious bilateral breast before row distending pain through back disappearance, show effect repeatedly, March is surplus to check UP and does B ultrasonic and the two breast scannings of infrared ray, pin and inhale breast nodule cytolgical examination Yong and examine and be cyclomastopathy, come my institute to go to a doctor and give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g), add with newborn precious medicine cover and put into each one of two breast brassiere, one course of treatment of medication, treatment back transference cure, tuberosity is subdued distending pain of the breast and is disappeared in the bilateral breast.Do not recur with anti-after 1 year.

2, Wang: woman 27 years old, Bei Tun forest farm, Xinjiang cadre, on March 14th, 2002 examined and is cyclomastopathy because of Physical Check-Ups (two newborn B ultrasonic scannings, noctovisor scan, pin are inhaled the breast nodule inspection) Yong.Conscious right breast distending pain can be touched bar hitch joint, tenderness is obvious, come my institute to go to a doctor and give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g), add with newborn precious medicine cover and put into each one of two breast brassiere, tuberosity is subdued the distending pain of the breast disappearance in the transference cure after medicine for treatment 15-30 days, bilateral breast.Do not recur with anti-after 1 year.

3, Lee: woman 23 years old, 181 cadres of Xinjiang Bei Tun farming ten teachers because of conscious right breast distending pain can be touched bar hitch joint, tenderness obviously comes me to examine prescription on individual diagnosis by gate, inhale the breast nodule inspection through two newborn B ultrasonic scannings, noctovisor scan, pin) Yong examines and is cyclomastopathy.Give Rubao capsule three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) adds with newborn precious medicine cover and puts into each one of two breast brassiere, and 15-30 days is a course of treatment, and tuberosity is subdued the distending pain of the breast disappearance in the transference cure after the medicine for treatment, bilateral breast.Do not recur with anti-after 1 year.

Four, the specific embodiment:

According to components by weight percent, choose:

Fructus Trichosanthis 30g rhizoma sparganic 15g Fructus Toosendan 20g

Rhizoma Chuanxiong 20g Rhizoma Curcumae 15g Caulis Spatholobi 30g

Flos Carthami 10g Radix Curcumae 20g Bulbus Fritillariae Thunbergii 30g

Semen Vaccariae 30g Radix Platycodonis 10g Spica Prunellae 60g

Rhizoma Cyperi 15g Even sticks up 15g Herba Taraxaci 30g

Rhizoma Dioscoreae Bulbiferae 10g Concha Ostreae 40g Scorpio 20g

The red Radix Paeoniae Alba 30g of corydalis tuber 20g Radix Asparagi 30g

Radix Scrophulariae 60g Fructus Aurantii 30g

The preparation method that the present invention relates to the medicine of a kind of treatment and prevention female mammary gland proliferation is to incapsulate and make the medicine cover after said medicine is ground not, sieved, mixes, sterilizes to form by quantitative package.

When treatment is used:

A: with medicine Rubao capsule of the present invention three times on the one, a 3-5 grain taking medicine after meal (every contains crude drug 0.1g) was a course of treatment in 30-60 days.

B: newborn precious medicine cover: circular textile sheet, diameter 8-10cm, weight 20-3g are put into each one of two breast brassiere, and 15-30 days is a course of treatment.

Claims (1)

1, plants the Chinese herbal and crude drugs preparations of treatment and prevention female mammary gland proliferation, form (Rubao capsule and newborn precious medicine cover) through strict processing and manufacturing.They include Chinese herbal medicine such as Spica Prunellae, Concha Ostreae, Radix Scrophulariae, Radix Asparagi, Bulbus Fritillariae Thunbergii, Radix Curcumae, Semen Vaccariae, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Cyperi, corydalis tuber, it is characterized in that, be to make by following step:

The parts by weight proportioning of wherein said each composition is (unit is gram):

Fructus Trichosanthis 30g rhizoma sparganic 15g Fructus Toosendan 20g

Rhizoma Chuanxiong 20g Rhizoma Curcumae 15g Caulis Spatholobi 30g

Flos Carthami 10g Radix Curcumae 20g Bulbus Fritillariae Thunbergii 30g

Semen Vaccariae 30g Radix Platycodonis 10g Spica Prunellae 60g

Rhizoma Cyperi 15g Even sticks up 15g Herba Taraxaci 30g

Rhizoma Dioscoreae Bulbiferae 10g Concha Ostreae 40g Scorpio 20g

The red Radix Paeoniae Alba 30g of corydalis tuber 20g Radix Asparagi 30g

Radix Scrophulariae 60g Fructus Aurantii 30g

Preparation method is to incapsulate and make the medicine cover after said medicine is ground not, sieved, mixes, sterilizes to form by quantitative package.