CN1631430A - Chinese medicinal ointment for treating bone diseases - Google Patents

Abstract

The invention relates to a traditional Chinese medicinal ointment for treating bone diseases, wherein the ointment comprises ledebouriella root, coralbean bark, notopterygium root, Chinese ephedra, safflower, asarum, centipede, camphor.

Description

A kind of Chinese medicinal ointment for the treatment of osteopathia

Technical field:

The present invention relates to a kind of Chinese medicine that is used for the treatment of osteopathia, especially relate to a kind of Chinese medicine unguentum that is used for the treatment of osteopathias such as bony spur or hyperosteogeny.

Background technology:

Bone trabecula at positions such as vertebra or edge, joint or articular surfaces increases with bone density and increases, and can oppress the nerve root at this position or cause the fibrous ring at these positions to destroy, and causes the part pain or radiation pain to occur, and has been accompanied by inflammatory reaction.This symptom is referred to as hyperosteogeny or bony spur, prolapse of lumbar intervertebral disc etc. usually.The pathogeny that this is sick is interpreted as " is numbness by wind, cold, wet closing " with theory of Chinese medical science, and numbness is promptly inaccessible obstructed, directly causes the muscle ligament tractive excessive, makes between bone and the bone that over-burden, adds fretting wear and the bone disease that produces.This disease also is that a kind of common joint of middle-aged and elderly people shows row property disease.

The medicine of the above-mentioned osteopathia of western medical treatment has aspirin (aspirin), nonsteroidal analgesic such as indometacin and ibuprofen etc., and central muscle relaxant such as chlorine are frustrated husky ancestor.Though these medicines can antiinflammatory, alleviating pain is attended by negative interactions such as headache, nauseating, vomiting behind the clothes, simultaneously hemogram and liver, renal function is also had certain influence, and can not effect a radical cure above-mentioned osteopathia.

Chinese medicine cures that osteopathia mainly comprises oral administration and through this dual mode of skin administration, in oral administration, adopts different medicines by the viewpoint of the Chinese medicine difference according to the state of an illness when the side's of sending medication.As to early stage and the obvious person of qi depression to blood stasis of falling ill, adopt the medicine that restores menstrual flow and invigorates blood circulation with muscles and tendons relaxing to alleviate pain, as Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Fructus Aurantii, Radix Notoginseng, Flos Carthami, Olibanum, Myrrha, Rhizoma Chuanxiong etc.; Cold-damp weight person is added with Rhizoma Zingiberis, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae etc.; And rheumatism weight person is added Medicine for the treatment of rheumatism and arthritis, as Radix Angelicae Pubescentis, parasitism, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Ramulus Cinnamomi and Herba Asari etc.; Also can select kidney-replenishing or kidney yin medicines such as Herba Taxilli, Radix Rehmanniae Preparata, Fructus Lycii, Fructus Ligustri Lucidi, Fructus Psoraleae, Herba Ecliptae for use to the long patient of the course of disease in addition.So oral administration needs the dialectical principle of controlling of executing, the medical skill of operator had higher requirement.At osteopathia, because percutaneous drug delivery need not be by the metabolism in digestive organs such as gastrointestinal and the liver, can directly act on painful area, the caused side effect of excessive administration that simultaneously can avoid oral medicine to produce, and can stop administration at any time, so percutaneous drug delivery is the main modes of osteopathia such as treatment by Chinese herbs bony spur or hyperosteogeny.

External application paste is the most frequently used dosage form of percutaneous drug delivery, and particularly for osteopathias such as treatment bony spur or hyperosteogenys, external application paste has unique effect." plaster of treatment bony spur and hyperosteogeny " as No. 1054291 bulletins of Chinese patent is exactly this class unguentum.This plaster is selected for use Moschus, Borneolum Syntheticum, the Radix Angelicae Dahuricae, Radix Notoginseng, Sanguis Draxonis and Plumbum preparatium and oil to boil and is formed.But, because Moschus and Borneolum Syntheticum etc. are valuable ingredients of Chinese medicine, so cause the raising of this medicine cost.And " a kind of external-use plaster for softening dry feces and dissipating mass " of No. 1144594 bulletins of Chinese patent selects for use 36-flavor Glutinous Chinese medicines such as Radix Et Rhizoma Rhei, the Radix Rehmanniae, Squama Manis to make.This plaster has the function of regulating meridians, balance internal organs, blood circulation promoting and blood stasis dispelling.For the Chinese medicine composition that constitutes Chinese patent medicine, except that should having higher curative effect, also need to consider whether aspect problem such as abundance of the whether convenient and raw material sources of preparation usually, in the ordinary course of things, component polygamy system more is inconvenient more.

Summary of the invention:

It is abundant and cost is lower, the eutherapeutic Chinese medicine unguentum that is used for the treatment of osteopathias such as bony spur or hyperosteogeny that task of the present invention provides a kind of raw material sources.

The Chinese medicinal ointment of treatment osteopathia proposed by the invention contains following bulk drugs: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 2～9 parts; Each 0.5～4 part of Herba Asari and Scolopendra; 0～1 part of Camphora.Wherein, Radix Saposhnikoviae is used to dispel the wind, wins wet and spasmolytic; Cortex erythrinae is used for expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; Rhizoma Et Radix Notopterygii is used for cold expelling, dispels the wind and remove and pain relieving; Rhizoma Cibotii be used to dispel the wind remove, strong waist knee joint; Herba Ephedrae is used for loosing the interspaces of skin and muscles, ventilative key, dispersing wind and cold; Flos Carthami is used for blood circulation promoting and blood stasis dispelling.The above-mentioned raw materials drug composition is made unguentum, and the drug effect of each raw material of distinguishing the flavor of can cooperatively interact, and finally can play blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, spasmolytic cold expelling, reducing swelling and alleviating pain function, and osteopathias such as treatment bony spur or hyperosteogeny are had beyond thought curative effect.

The crude drug of unguentum proposed by the invention also can be added with: respectively 2～9 parts of Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, Ramulus Cinnamomi.Wherein, Radix Clematidis is used for expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; Radix Angelicae Pubescentis is used for atmosphere of news service dehumidifying, pain relieving; Because Herba Aristolochiae Mollissimae energy wind-damp dispelling, the meridian dredging, pain relieving; Herba Lycopodii can be used for expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral; Agkistrodon is used for the atmosphere of news service collateral dredging; Radix Achyranthis Bidentatae is used for blood circulation promoting and blood stasis dispelling; Olibanum is used for promoting blood circulation and stopping pain, the detumescence society stasis of blood; Semen Persicae is used for blood circulation promoting and blood stasis dispelling; Myrrha is used for promoting blood circulation and stopping pain, detumescence and promoting granulation; Rhizoma Dioscoreae Nipponicae is used for expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain; Herba Taxilli is used for blood rheumatism; Rhizoma Chuanxiong is used for blood-activating and qi-promoting, wind-expelling pain-stopping; Lignum Sappan is used for blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; Ramulus Cinnamomi is used for relieving the exterior syndrome by diaphoresis, warming the meridian for promoting the flow of YANG QI.So, add above-mentioned each crude drug after, can further improve its curative effect.

The optimum weight share of the contained crude drug of described Chinese medicinal ointment is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 3～6 parts; Each 1～3 part of Herba Asari and Scolopendra; 0.02～0.6 part of Camphora.

The consumption of described Chinese medicinal ointment crude drug is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 5 parts; Each 1.5 parts of Herba Asari and Scolopendras; 0.3 part of Camphora.

Described crude drug also contains: respectively 2～9 parts of Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, Ramulus Cinnamomi.

The consumption of described each component is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 5 parts; Each 1.5 parts of Herba Asari and Scolopendras; 0.3 part of Camphora; Respectively 5 parts of Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, Ramulus Cinnamomi.

Adopt conventional method to make the black powder unguentum above-mentioned raw materials medicine.For example crude drug is ground into mix homogeneously behind the powder powder, and, adds Plumbum preparatium and make by behind the Oleum Sesami high temperature extraction.

Below further specify the curative effect of unguentum proposed by the invention by clinical case.

With osteopathia patients such as unguentum proposed by the invention treatment hyperosteogeny totally 136 examples, the age is between 34 to 67 years old.Wherein, hyperosteogeny of cervical vertebra case 25 people, prolapse of lumbar intervertebral disc case 29 people, lumbar vertebra hyperosteogeny case 21 people, lumbar spinal stenosis 18 people, scapulohumeral periarthritis 17 people, anconitis 14 people, gonarthritis 12 people.Because the pathogeny and the symptom of above-mentioned various osteopathias are basic identical, so not classification only provides total curative effect statistical table in the table 1.

Table 1 is observation of curative effect after treating

Treatment time the sky	Produce effects		Take a turn for the better		Invalid		Effective percentage %
									The example number	Obvious effective rate %	The example number	Improvement rate %	The example number	Inefficiency %
5	18	13.2％	116	85.3％	2	1.15％	98.85％
								15	72	52.9％	62	45.6％	2	1.15％	98.85％
20	114	83.8％	20	14.7％	2	1.15％	98.85％
								30	134	98.5％	0	0	2	1.15％	98.85％

It is a course of treatment that this ointment sticks 15 days, shows through clinical treatment, use this kind plaster treatment osteopathia through two courses of treatment after, produce effects is 134 examples, effective percentage is more than 98%.Two invalid routine skin allergy or because of wound causes ostealleosis, its pathogeny is different with the osteopathia that the present invention is treated.

The specific embodiment:

Embodiment 1

Take by weighing Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami, Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, each 10 gram of Ramulus Cinnamomi; Each 2 gram of Herba Asari and Scolopendra; Camphora 0.04 gram.Above-mentioned medicine system granule or the powder shape of respectively distinguishing the flavor of put into container, produce cream type preparation, then the plaster branch that makes is installed on the object such as plaster constraint bag grade by traditional method, and when packing, should be according to the position different dosing of required treatment.

Claims (5)

1. Chinese medicinal ointment for the treatment of osteopathia, it is characterized in that: this Chinese medicinal ointment contains following bulk drugs: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification sign grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami and are respectively 2～9 parts; Each 0.5～4 part of Herba Asari and Scolopendra; 0～1 part of Camphora.

2. Chinese medicinal ointment according to claim 1 is characterized in that: the optimum weight share of the contained crude drug of described Chinese medicinal ointment is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 3～6 parts; Each 1～3 part of Herba Asari and Scolopendra; 0.02～0.6 part of Camphora.

3. Chinese medicinal ointment according to claim 1 is characterized in that: the consumption of described Chinese medicinal ointment crude drug is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 5 parts; Each 1.5 parts of Herba Asari and Scolopendras; 0.3 part of Camphora.

4. Chinese medicinal ointment according to claim 1 is characterized in that: described crude drug also contains: respectively 2～9 parts of Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, Ramulus Cinnamomi.

5. Chinese medicinal ointment according to claim 4 is characterized in that the consumption of each component is: Radix Saposhnikoviae, Cortex erythrinae, Limitation-or-qualification label grass, Rhizoma Et Radix Notopterygii, Rhizoma Cibotii, Herba Ephedrae, Flos Carthami are respectively 5 parts; Each 1.5 parts of Herba Asari and Scolopendras; 0.3 part of Camphora; Respectively 5 parts of Radix Clematidis, Radix Angelicae Pubescentis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Agkistrodon, Radix Achyranthis Bidentatae, Olibanum, Semen Persicae, Myrrha, Rhizoma Dioscoreae Nipponicae, Herba Taxilli, Rhizoma Chuanxiong, Lignum Sappan, Ramulus Cinnamomi.