CN1628829A - Chinese medicine for treating hypertension, high blood fat and high blood sugar - Google Patents
Chinese medicine for treating hypertension, high blood fat and high blood sugar Download PDFInfo
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Abstract
Disclosed is a Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases, which is prepared by using matrimony vine, fleece-flower root, ginkgo as main components and other Chinese medicinal herbs. The preparation employs the procedures of ultra-fine powder water grilling, concentrating, and grease forming.
Description
Technical field
The present invention relates to the field of Chinese medicines, especially treat the field of Chinese medicines of cardiovascular and cerebrovascular disease.
Background technology
Entered since 21 century, along with socioeconomic fast development, the people's living standard improves constantly.Simultaneously, the factor such as increase the weight of of the quickening of the increasing of the change of dietary habit, bad habit, work rhythm and social pressure causes the sickness rate of various diseases to increase substantially.Especially " three-hypers " crowds such as hypertension, hyperlipidemia, hyperglycemia, caused human sub-health state ubiquity, according to Ministry of Public Health statistics whole nation in 2003 9000 ten thousand people are arranged approximately altogether, suffers from the easiest generation that causes diseases such as cerebral thrombosis, cerebral hemorrhage, coronary heart disease of crowd of above-mentioned " three-hypers ", and age of onset is rejuvenation day by day, caused global attention, cardiovascular and cerebrovascular disease has been classified as first killer of harm humans health by World Health Organization (WHO).According to statistics, nearly 32% people dies from cardiovascular and cerebrovascular disease in the annual death, not only human beings'health is caused great threat, has also increased the weight of social burden.
At present, it is not single disease that quite a few cardiovascular and cerebrovascular vessel patient is arranged, but various disease conditions exists simultaneously.As suffering from hypertension, hyperlipidemia or hyperglycemia simultaneously.And market supply is the medicine of only treating single disease mostly, will take multiple medicine simultaneously for the patient who suffers from various disease conditions such as hypertension, hyperglycemia, hyperlipidemia simultaneously, has brought inconvenience to the patient.Some medicine also exists curative effect can not be lasting, has a rebound after the drug withdrawal, must for a long time continual shortcoming of taking.The curative effect of these problems affect person's medicines increases financial burden to the patient.
Summary of the invention
Diseases such as hypertension, hyperlipidemia, hyperglycemia, the Chinese medicine of stable disease after the drug withdrawal can effectively be treated and treat to purpose of the present invention for providing a kind for the treatment of both the principal and secondary aspects of a disease effect lasting.
The basic recipe of Chinese medicine of the present invention is to be made by the following traditional Chinese medicines material: Radix Polygoni Multiflori 3-30 gram, Fructus Lycii 1-30 gram, Folium Ginkgo 3-60 gram.
Prescription after the present invention's process is improved: except that containing above-mentioned Chinese crude drug, also contain Fructus Mori 3-60 gram, Fructus Ligustri Lucidi 3-40 gram, Radix Angelicae Sinensis 3-20 gram, Rhizoma Chuanxiong 2-30 restrains, Hirudo 0.5-4.5 gram.
The present invention improves through further again above-mentioned improved prescription: also contain Pheretima 3-15 gram except that containing above-mentioned Chinese crude drug, Radix Salviae Miltiorrhizae 20-30 gram, Herba Apocyni veneti 2-30 gram, Herb Gynostemmae Pentaphylli 2-10 restrain.
Contained Chinese crude drug in above-mentioned each prescription has following effect:
Radix Polygoni Multiflori: contain chrysophanic acid, gallic acid, Radix Polygoni Multiflori second element and third element, have blood fat reducing, arteriosclerosis, function in delaying senility.
Fructus Mori: contain tannic acid, malic acid, VB1, VB2, VB3 and carotene, have functions such as blood vessel dilating, nourishing YIN and benefiting blood, hypnotic, the intestine moistening of promoting the production of body fluid.
Fructus Ligustri Lucidi: contain oleanolic acid, ursolic acid and various trace elements, have blood sugar lowering, improve the effect of superoxide dismutase, also contain active substance such as nicotinic acid, aminoacid, be the main component that cell generates, can promote the growth metabolism of cell, recover young physiological status.
Fructus Lycii: be rich in several amino acids such as nicotinic acid, lycium barbarum polysaccharide, atropine, have the effect of expansion vessel softening, can blood circulation promoting and the interior refuse effect of eliminating body.
Folium Ginkgo: containing effective ingredient such as flavonoid glycoside, oleanolic acid, have and remove the interior lipid of being retarded by silt of blood vessel and the effect of cholesterol, is blood fat reducing good medicine.
Radix Angelicae Sinensis: contain nicotinic acid, angelic acid and volatile oil, have anticoagulant, antithrombotic and form, blood fat reducing, blood vessel dilating, blood pressure lowering, effects such as enhancing immunity have invigorating blood circulation, change the effect of blood.
Rhizoma Chuanxiong, Hirudo: have the arteriosclerosis of alleviating, stop the effect of platelet aggregation, be used to prevent and treat cerebral thrombosis and myocardial infarction.
Pheretima, Radix Salviae Miltiorrhizae: have activating blood and removing stasis, refrigerant pain relieving stops the effect of platelet aggregation.
Herba Apocyni veneti: have refrigerant, blood pressure lowering, the effect of diuresis of blood circulation promoting.
Herb Gynostemmae Pentaphylli: contain gallic acid, have the effect of blood fat reducing.
The present invention has broken through the traditional Chinese medical science traditional " monarch, minister, help, make the medicine combination principle ", learns research theory in conjunction with modern Chinese medicine, will have collaborative mutually Chinese medicine reasonable compatibility.Show from the above-mentioned effective ingredient that contains, it has been rich in flavonoid glycoside, oleanolic acid, nicotinic acid, gallic acid, vitamin C, B1, B2, various trace elements such as carotene and zinc-iron calcium, can expand vessel softening at short notice after taking, increase blood vessel elasticity, increase the hemoperfusion amount, reduce pressure to blood vessel wall, remove the lipid and the cholesterol that are retarded by silt in the blood vessel, promote to drain, restrain hematoblastic gathering, alleviate arteriosclerosis and antithrombotic and form, improve organ dysfunction, reach blood pressure regulation, blood fat reducing, the multi-functional effect of carrying out synchronously of blood sugar lowering one medicine, the base substance of additional a large amount of synthetic cells promotes cell division simultaneously, propagation, make cell development vigorous, improve the super oxidasic active organism physiology blood supply state of regulating, reach slow down aging, the effect of poliosis blackening and hair growth promoting.
Medicine of the present invention also has the effect for the treatment of both the principal and secondary aspects of a disease, can not only a medicine be multi-functional carries out synchronously with blood pressure regulation, blood fat reducing, blood sugar lowering etc., the softening hardened blood vessel of expansion is removed the absorption again, the mitigation symptoms that are retarded by silt in endovascular cholesterol, lipid and metabolite, retardance intestinal; And then recover the normal physiological function of each organs such as liver, kidney, the heart, brain, pancreas, and keep the young state of organ to prevent the formation of new pathological changes, make the effect of poliosis blackening and hair growth promoting simultaneously in addition.
The preparation method of basic recipe medicine of the present invention is as follows:
(1) Fructus Lycii is worn into the micron-class superfine powder, standby;
(2) with the Radix Polygoni Multiflori breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extract filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in Folium Ginkgo is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) the Fructus Lycii superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
The preparation method of all the other two kinds of improved prescriptions is as follows:
(1) Fructus Lycii, Radix Angelicae Sinensis, Hirudo are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori, Fructus Ligustri Lucidi breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in all the other medical materials is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Medicine of the present invention in clinic trial 126 examples, wherein, male's 79 examples, women's 47 examples; Minimal ages 35 years old, at maximum 83 years old age, 45-60 year, 102 examples accounted for 80%; Hyperpietic's 33 examples wherein, hyperlipemic patients 73 examples, hyperglycemic patients 20 examples.Cerebral arteriosclerosis patient 80 examples wherein wherein suffer from patient's 39 examples of hypertension, hyperlipidemia, hyperglycemia simultaneously.The patient takes 15 grams at every turn, takes secondary every day.Wherein there are 109 examples (accounting for 86.5%) to take after 2-5 days headache, sx or disappearance such as dizzy, nervous, uncomfortable in chest.All the other 17 examples (accounting for 13.5%) have been taken sx or disappearance after 6-10 days, so total effective rate is 100%.Now taking per course of treatment is 15 days, checks blood pressure, blood fat, blood glucose, rheoencephalogram, electrocardiogram etc. after taking 1 course of treatment, and the state of an illness all has and significantly alleviates, the recovery that has normal, among cure rate is being added up at present.
Chinese medicine of the present invention through said method is made has following characteristics:
1, because has collaborative mutually Chinese medicine reasonable compatibility, auxilliary mutually the use, make hardened vasodilation softening, remove at endovascular cholesterol, lipid and metabolite being retarded by silt, and the absorption again in the retardance intestinal, finally reach the multi-functional effects of a medicine such as blood pressure regulation, blood fat reducing, blood sugar lowering.
2, can recover and improve the normal physiological function of each organs such as liver, kidney, the heart, brain, pancreas, prevent the formation of new pathological changes, prevent the disease bounce-back, curative effect is lasting, stable disease.
3, pack with the form of decoction, kept the advantage of Chinese medicine decoction, both made things convenient for patient to take, kept the useful effect of Chinese medicine again, take the back active substance and discharge rapidly, absorb complete definite effect.
The specific embodiment
The embodiment of basic recipe medicine:
Prescription: Radix Polygoni Multiflori 15 grams, Fructus Lycii 12 grams, Folium Ginkgo 20 grams.
Preparation method:
(1) Fructus Lycii 12 grams are worn into granule and be 50 microns superfines, standby;
(2) with Radix Polygoni Multiflori 15 gram breaking cellular walls, add 105 milliliters water, decocting 120 minutes filters the back and extracts filtrate, adds 30 milliliters water in filtering residue again, carries out the decocting second time, extracts filtrate for the second time through 60 minutes after-filtration, and twice filtrate is mixed, standby;
(3) add 140 milliliters water in Folium Ginkgo 20 gram, decocting 120 minutes filters the back and extracts filtrate, adds 40 milliliters water in filtering residue again, and decocting 100 minutes filters the back and extracts filtrate for the second time, and twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned Radix Polygoni Multiflori and Folium Ginkgo mixes, and reconcentration is to the 100-110 milliliter.
(5) the Fructus Lycii superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to the 45-50 milliliter, the gained mastic is carried out packing while stir to 100 ℃; Each packing 15 gram;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Embodiment to the improved magistral medicines of basic recipe:
Prescription: Radix Polygoni Multiflori 10 grams, Fructus Lycii 10 grams, Folium Ginkgo 20 grams, Fructus Mori 20 grams, Fructus Ligustri Lucidi 15 grams, Radix Angelicae Sinensis 12 grams, Rhizoma Chuanxiong 15 grams, Hirudo 3 grams.
Preparation method:
(1) Fructus Lycii 10 gram, Radix Angelicae Sinensis 12 grams, Hirudo 3 grams being worn into granule is 50 microns superfines, standby;
(2) with Radix Polygoni Multiflori 10 grams, Fructus Ligustri Lucidi 15 gram breaking cellular walls, add 175 ml waters, decocting 120 minutes, filter the back and extract filtrate, in filtering residue, add 50 ml waters again, carry out the decocting second time, after filtering, extract 60 minutes decoctings filtrate for the second time, and twice filtrate is mixed, standby;
(3) Folium Ginkgo 20 grams, Fructus Mori 20 grams, Rhizoma Chuanxiong 15 grams are put together, add 385 ml waters, decocting 120 minutes, filter the back and extract filtrate, in filtering residue, add 110 ml waters again, carry out the decocting second time, extract filtrate for the second time through 100 minutes after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid of above-mentioned steps (2), (3) gained is mixed, reconcentration to 240 milliliter, standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to 105 milliliters, the gained mastic is carried out packing, whenever be packaged as the 12-15 gram while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Embodiment to the further improved magistral medicines of basic recipe:
Prescription: Radix Polygoni Multiflori 10 grams, Fructus Lycii 12 grams, Folium Ginkgo 15 grams, Fructus Mori 15 grams, Fructus Ligustri Lucidi 12 grams, Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 12 grams, Hirudo 2 grams, Pheretima 5 grams, Radix Salviae Miltiorrhizae 10 grams, Herba Apocyni veneti 10 grams, Herb Gynostemmae Pentaphylli 3 grams.
Preparation method:
(1) Fructus Lycii 12 gram, Radix Angelicae Sinensis 10 grams, Hirudo 2 grams being worn into granule is 50 microns superfines, standby;
(2) with Radix Polygoni Multiflori 10 grams, Fructus Ligustri Lucidi 12 gram breaking cellular walls, add 150 ml waters, decocting 120 minutes, filter the back and extract filtrate, in filtering residue, add 45 ml waters again, carry out the decocting second time, after filtering, extract 60 minutes decoctings filtrate for the second time, and twice filtrate is mixed, standby;
(3) Folium Ginkgo 15 grams, Fructus Mori 15 grams, Rhizoma Chuanxiong 12 grams, Pheretima 5 grams, Radix Salviae Miltiorrhizae 10 grams, Herba Apocyni veneti 10 grams, Herb Gynostemmae Pentaphylli 3 grams are put together, add 500 ml waters, decocting 120 minutes, filter the back and extract filtrate, add 150 ml waters in filtering residue again, decocting 60 minutes filters the back and extracts filtrate for the second time, twice filtrate is mixed, standby;
(4) the decocting liquid of above-mentioned steps (2), (3) gained is mixed, reconcentration to 300 milliliter, standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to 116 milliliters, the gained mastic is carried out packing, whenever be packaged as the 12-15 gram while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Claims (6)
1, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar is characterized by the Chinese crude drug that contains following proportioning weight and makes: Radix Polygoni Multiflori 3-30 gram, Fructus Lycii 1-30 gram, Folium Ginkgo 3-60 gram.
2, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 1 is characterized by and also contains Fructus Mori 3-60 gram, Fructus Ligustri Lucidi 3-40 gram, Radix Angelicae Sinensis 3-20 gram, Rhizoma Chuanxiong 2-30 gram, Hirudo 0.5-4.5 gram.
3, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 2 is characterized by and also contains Pheretima 3-15 gram, Radix Salviae Miltiorrhizae 2-30 gram, Herba Apocyni veneti 2-30 gram, Herb Gynostemmae Pentaphylli 2-10 gram.
4, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 1 is characterized by preparation method and is made up of the following step:
(1) Fructus Lycii is worn into the micron-class superfine powder, standby;
(2) with the Radix Polygoni Multiflori breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extract filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in Folium Ginkgo is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) the Fructus Lycii superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
5, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 2 is characterized by preparation method and is made up of the following step:
(1) Fructus Lycii, Radix Angelicae Sinensis, Hirudo are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori, Fructus Ligustri Lucidi breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in all the other medical materials is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
6, a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 3 is characterized by preparation method and is made up of the following step:
(1) Fructus Lycii, Radix Angelicae Sinensis, Hirudo are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori, Fructus Ligustri Lucidi breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in all the other medical materials is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200410073874 CN1628829B (en) | 2004-09-07 | 2004-09-07 | Chinese medicine for treating hypertension, high blood fat and high blood sugar |
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| CN 200410073874 CN1628829B (en) | 2004-09-07 | 2004-09-07 | Chinese medicine for treating hypertension, high blood fat and high blood sugar |
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| CN1628829A true CN1628829A (en) | 2005-06-22 |
| CN1628829B CN1628829B (en) | 2010-10-13 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526358A (en) * | 2012-02-13 | 2012-07-04 | 赵树刚 | Medicinal composition for treating diabetes and preparation method thereof |
| CN104857328A (en) * | 2015-04-24 | 2015-08-26 | 吴中区胥口精益生物医药研究所 | Blood sugar reducing traditional Chinese medicine white chrysanthemum, angelica dahurica, radix paeoniae alba, white poria cocos and gingko nut porridge and making method thereof |
| CN107568746A (en) * | 2017-10-16 | 2018-01-12 | 海南三元星生物科技股份有限公司 | A kind of health food containing oceanic shellfish active peptide and preparation method thereof |
| CN107828592A (en) * | 2017-12-05 | 2018-03-23 | 广西强象生物科技有限公司 | A kind of Moringa magma nutritious white spirit and its manufacture craft |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1123347C (en) * | 2000-06-16 | 2003-10-08 | 杨传平 | Chinese medicine for decreasing fat and lossing weight and preparation method thereof |
| CN1131054C (en) * | 2001-07-09 | 2003-12-17 | 江秉娥 | Chinese herbal medicine for treating hypertension |
-
2004
- 2004-09-07 CN CN 200410073874 patent/CN1628829B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526358A (en) * | 2012-02-13 | 2012-07-04 | 赵树刚 | Medicinal composition for treating diabetes and preparation method thereof |
| CN102526358B (en) * | 2012-02-13 | 2013-07-31 | 赵树刚 | Medicinal composition for treating diabetes and preparation method thereof |
| CN104857328A (en) * | 2015-04-24 | 2015-08-26 | 吴中区胥口精益生物医药研究所 | Blood sugar reducing traditional Chinese medicine white chrysanthemum, angelica dahurica, radix paeoniae alba, white poria cocos and gingko nut porridge and making method thereof |
| CN107568746A (en) * | 2017-10-16 | 2018-01-12 | 海南三元星生物科技股份有限公司 | A kind of health food containing oceanic shellfish active peptide and preparation method thereof |
| CN107568746B (en) * | 2017-10-16 | 2021-04-20 | 海南华研胶原科技股份有限公司 | Health food containing active peptide of marine shellfish and preparation method thereof |
| CN107828592A (en) * | 2017-12-05 | 2018-03-23 | 广西强象生物科技有限公司 | A kind of Moringa magma nutritious white spirit and its manufacture craft |
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| Publication number | Publication date |
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| CN1628829B (en) | 2010-10-13 |
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