CN1420754A

CN1420754A - Sealing device for injection/extraction port of liquid drug

Info

Publication number: CN1420754A
Application number: CN 01807378
Authority: CN
Inventors: 深井昭寿; 池上毅; 奥井禧仁
Original assignee: Fukai Kogyo KK
Current assignee: Fukai Kogyo KK
Priority date: 2001-02-09
Filing date: 2001-07-03
Publication date: 2003-05-28
Also published as: TW504394B; JP2002306610A; WO2002064077A1

Abstract

A liquid medicine or the like injection and extraction port seal valve comprises a plug main body (1) in the form of an elastic body formed with a linear cut portion (1a) or slit portion (1f) in the central region vertically extending therethrough, the outer diameter (D1) of the plug main body (1) being larger than the inner diameter (D2) of an injection and extraction port (2a) for liquid medicine, the arrangement being such that tightly fitting the plug main body (1) in the injection and extraction port (2a) for liquid medicine or the like produces a clamping pressure on the cut portion (1a) or slit portion (1f) to seal it. The cut portion (1a) or slit portion (1f) of the plug main body (1) is elastically deformed to open by tightly fitting the front end portion (3) of a syringe or connector, and is elastically restored to its original sealed state by pulling out the front end portion (3) of the syringe or connector.

Description

Mouth sealing device is extracted in the injection of liquid preparation etc. out

Technical field

Mouth sealing device is extracted in the injection that the invention relates to a kind of liquid preparation etc. of the field that is used for medicine out, and front end that can be by syringe or connecting elements partly directly injects or extracts liquid preparation etc. out.And under situation in the mixing ascending pipe that is used to transmit blood will be extracted or will be injected into when liquid preparation to liquid preparation from liquid preparation bottle or liquid preparation vessel out, must not use injection needle.

Background technology

Device of the present invention has a gland main body, this gland main body is provided with front end cutting port part, jaws part or the conical bore partly that can insert syringe or connecting elements, in the injection that this gland main body can closely fill in liquid preparation bottle, liquid preparation vessel, mix one of liquid preparation such as ascending pipe or the object similar with it etc. is extracted out mouthful, and make cutting port part, jaws part or conical bore can produce clamp pressure, and this clamp pressure can make cutting port part, jaws part or conical bore seal up.So, can prevent that liquid preparation etc. from leaking outside, and can prevent also that the gland main body from extracting out from the injection of liquid preparation etc. and mouthful come off.The injection of liquid preparation or extract the cutting port part, jaws part or the conical bore that then utilize the opposing clamp pressure and the front end of syringe or connecting elements partly is inserted into the gland main body out to carry out it.

Moreover, device of the present invention, the internal diameter that the external diameter of its gland main body can be extracted out mouthful greater than the injection of liquid preparation etc., when so the injection that closely is tucked into liquid preparation etc. when the gland main body is extracted out in the mouth, will produce clamp pressure, do not need the configuration of auxiliary part, and can prevent that situation about getting loose from taking place.

In addition, in meaning field at medicine, the alleged adapter of this description is applied in the machine or the instrument of transmission blood, nutrient or medicine class, and this adapter can be connected to a pipe or similar object, and liquid etc. can be shipped from supplying with the source by this pipe, wherein above-mentioned flowing fluid ratio is liquid preparation or nutrient in this way.

As shown in figure 24, the bottle stopper of traditional liquid ampoule comprises a rubber plug 22 (rubberplug) and a lid cover 24 (cap), wherein rubber plug 22 is tucked in liquid preparation injection extraction mouthful 21 (the liquid medicine injection andextraction port) of bottle main body 20 (bottlemain body), and lid cover 24 can cover rubber plug 22, and can be fixed on the bottleneck flange 23 (bottle mouth flange).So when liquid preparation will be extracted out, the zone line of lid cover 24 must be peelled off, perhaps will make one in advance is opened in the rubber plug 22, so be inserted in the above-mentioned opening by the syringe needle 26 (needle) of position at syringe 25 front ends, and enter into the inside of rubber plug 22, and can the sucking-off position at the liquid preparation of inside.

In addition, as shown in figure 25, traditional mixing ascending pipe comprises a T type tube body 30 (T-shaped main body), a rubber plug 32 and a lid cover 33, wherein a side of T type tube body 30 has partly 31 (branch tube portion) of a bifurcated tubulose, rubber plug 32 is entrenched togather with 31 sealings of bifurcated tubulose part, and by lid cover 33 rubber plug 32 is fixed and positioned.T type tube body 30 can insert or be connected in the pipeline of transmission blood, such as the pipeline that is pipeline, drop pipeline or the similar appliances of manually washing the kidney instrument, and can insert in the rubber plug 32 that puts in place in bifurcated tubulose part 31 by the syringe needle 26 of position at syringe 25 front ends, so the position can be injected in the pipeline of transmission blood at syringe 25 main intravital liquid preparations.

Traditional sealing device is configured in the liquid preparation bottle or mixes on the liquid preparation injection extraction mouth of ascending pipe, and in use, must will utilize syringe needle to be inserted in the rubber plug, so can increase the cost that uses syringe needle.Moreover, also must handle exhausted syringe needle by SC, to prevent the pollution of patient blood antibacterial,, can cause the generation of infectious disease if deal with improperly.

Summary of the invention

Above-mentioned traditional problem is very serious, for addressing the above problem, purpose of the present invention is exactly that mouth sealing device is extracted in the injection that proposes a kind of liquid preparation etc. out, utilize syringe need not utilize syringe needle, just can from liquid preparation bottle or similar object, extract liquid preparation out, perhaps inject liquid preparation to mixing ascending pipe.

Device of the present invention has a gland main body, this gland main body has cutting port part, jaws part or conical bore, and in the gland main body can closely be configured in liquid preparation bottle, liquid preparation vessel, the injection that mixes liquid preparation on ascending pipe or the object similar with it etc. extracts out mouthful, and make above-mentioned cutting port part, jaws part or conical bore be subjected to the clamp pressure effect, and this clamp pressure can make cutting port part, jaws part or conical bore seal up.So, can prevent that liquid preparation etc. from leaking outside, and can prevent also that the gland main body from extracting out from the injection of liquid preparation etc. and mouthful come off.

The injection of liquid preparation or extraction can partly be inserted into the front end of syringe or connecting elements by resisting above-mentioned clamp pressure on cutting port part, jaws part or the conical bore of gland main body to carry out it.

According to a preferred embodiment of the present invention, mouth sealing device is extracted in the injection of a kind of liquid preparation etc. out, comprise a gland main body, the gland main body is similar elastomer cylindraceous, the gland main body has a valve film, valve film position is at the zone line of gland main body, and the valve film has a cutting port part, one jaws part or a conical bore, cutting port part, jaws part or conical bore position are at the zone line of valve film, so when applying an external pressure on the gland main body time from the outside with the direction of radius, cutting port part, jaws part or conical bore can be subjected to a clamp pressure effect, make cutting port part by this clamp pressure, jaws part or conical bore present the state of sealing.In the time of wherein in the injection that the gland main body is configured to a liquid preparation etc. is extracted out mouthful, can produce external pressure.And the internal diameter that the external diameter of gland main body can be extracted out mouthful greater than the injection of liquid preparation etc. in the time of so in the injection that the gland main body will be tucked into liquid preparation etc. is extracted out mouthful, has the resistance generation.When the injection that is installed in liquid preparation etc. when the gland main body is extracted out and mouthful is gone up, can around the gland main body, produce stress, elastic force, and the stress effect of pushing, can produce clamp pressure in cutting port part or the jaws part this moment, so can present the state of sealing in cutting port part or the jaws part.Therefore, in the time of in the injection that if the gland main body closely is configured in liquid preparation bottle, liquid preparation vessel, mix liquid preparation on ascending pipe or the object similar with it etc. is extracted out mouthful, can prevent that liquid preparation, blood or similar substance from draining to the external world from liquid preparation bottle, liquid preparation vessel, inside and outside mixing ascending pipe this moment.When the injection of liquid preparation or extraction, the front end of syringe or connecting elements partly is inserted in the cutting port part or jaws part of gland main body, and the cutting port part of gland main body or jaws part can flexibly be out of shape and open, and can carry out the injection or the extraction of liquid preparation etc.In sum, according to the present invention, when to be injected into liquid preparation bottle, liquid preparation vessel, when mixing in the ascending pipe or will be from liquid preparation bottle, liquid preparation vessel, mix extract out in the ascending pipe time, do not need to utilize syringe needle, therefore the problem that can avoid syringe needle to cause.And when the front end of syringe or connecting elements was partly extracted in the cutting port part of gland main body or jaws part, the cutting port part of gland main body or jaws part can bounce back into original state and present the state of sealing.

The gland main body also has an overhang, and the overhang position is in the periphery of gland main body, and perpendicular to the bearing of trend of the length of cutting port part or jaws part.More can increase the cutting port part of gland main body or the clamp pressure of jaws part by this overhang, and the effect of further lift-off seal.

When irritating molded when making the gland main body, the jaws part of gland main body just completes, and jaws part is the kenel of an elongated opening, and jaws part can vertically run through the gland main body.So, can omit the step of making cutting port part.

The formed long strip type opening of jaws part is parallel to the vertical direction of this gland main body.So when a pressure be applied to jaws part above or below the time, similarly, can bring into play the effect of sealing.

And the formed long strip type opening of jaws part, its cross sectional shape can be the shape of V-shape and inverted V-shape, and the size of long strip type opening is being prolonged the vertical direction of gland main body and is increased gradually or dwindle.When jaws part was designed to the shape of V-shape, if (that is inside of liquid preparation bottle or similar object) formed pressure is healed when big below the gland main body, then sealing effectiveness can be better, so above-mentioned design is suitable for being applied in the situation with internal pressure.And when jaws part was designed to the shape of inverted V-shape, if heal when big at the outside institute applied pressure of liquid preparation bottle or similar object, then sealing effectiveness can be better, so above-mentioned design is suitable for being applied in the situation with external pressure.

In the time of in the front end of syringe or connecting elements partly is tucked into the cutting port part of gland main body or jaws part, the cutting port part of gland main body or jaws part can flexibly be out of shape and open, when the front end of syringe or connecting elements was partly extracted in the cutting port part of gland main body or jaws part, the cutting port part of gland main body or jaws part can bounce back into original state and present the state of sealing.So in the injection of liquid preparation etc. or when extracting out, the front end of syringe or connecting elements partly can be inserted in the cutting port part or jaws part of gland main body, make the elastomer of position around cutting port part or jaws part flexibly to be out of shape and open, and can carry out the injection or the extraction of liquid preparation etc.And when the front end of syringe or connecting elements is partly extracted in the cutting port part of gland main body or jaws part, the elastomer of position around cutting port part or jaws part can bounce back into original state and present the state of sealing, and can prevent in the liquid preparation bottle or the intravital liquid of analog has the situation that leaks outside.

The thickness of the peripheral region of gland main body can so can increase the position at the clamp pressure on the cutting port part or on the jaws part greater than the thickness of the zone line of gland main body.

The vertical thickness of the zone line of gland main body can be for uniformly, and the vertical thickness of the peripheral region of gland main body can so also can increase the position at the clamp pressure on the cutting port part or on the jaws part for what increase gradually.

The vertical thickness of gland main body can increase toward the peripheral region gradually from middle zone, so can also increase the position at the clamp pressure on the cutting port part or on the jaws part.

The gland main body has at least one depressed part, wherein when this gland main body only has a depressed part, the depression position is on the upper surface of gland main body or the zone line on the lower surface, when the gland main body had two depressed parts, two depressed parts difference position was at the zone line that reaches on the upper surface of gland main body on the lower surface.So the thickness of the peripheral region of gland main body can be greater than the thickness of the zone line of gland main body, and can increase the position at the clamp pressure on the cutting port part or on the jaws part.

The position can be greater than the diameter of position at the depressed part of gland main body upper surface at the diameter of the depressed part of gland main body lower surface, and the inner circumferential surface of position in the depressed part of gland main body lower surface and the corner of roof intersection are circular-arc pattern, so the position can increase at the clamp pressure on the cutting port part or on the jaws part, simultaneously in the liquid preparation vessel or the thing intravital internal pressure similar with it can increase, thereby can improve in the liquid preparation vessel or the situation of the thing intravital liquid leakage similar with it.In the time of when the front end of syringe or connecting elements partly is tucked into the cutting port part of gland main body or jaws part from the outside in, the elastomer of position around cutting port part or jaws part can flexibly be out of shape and open, thereby can inject or extract out liquid.When the front end of syringe or connecting elements was partly extracted in the cutting port part of gland main body or in the jaws part, the cutting port part of gland main body or jaws part can bounce back into original state and present the state of sealing.Moreover, because the inner circumferential surface of position in the depressed part of gland main body lower surface and the corner of roof intersection are circular-arc pattern, therefore in the time of in the front end of syringe or connecting elements partly is inserted into the cutting port part of gland main body or in the jaws part, the elastomeric pressure that rebounds can increase, so can increase the reliability of sealing.

The position is at front end partly the external diameter of the formed diameter in the surface, inside of the depressed part of gland main body upper surface zone line less than syringe or connecting elements, therefore partly be inserted in the zone line of depressed part and the cutting port part or in the jaws part when the front end of syringe or connecting elements, during with the action of the injection of carrying out liquid preparation etc. or extraction, can prevent that liquid preparation etc. from leaking outside from depressed part, and can more firmly engage with syringe or connecting elements.

The position has a circular protrusion partly at the depressed part of this gland main body upper surface, and circular protrusion internal diameter partly is slightly less than the front end external diameter partly of syringe or connecting elements, so partly be inserted in the zone line of depressed part and the cutting port part or in the jaws part when the front end of syringe or connecting elements, during with the action of the injection of carrying out liquid preparation etc. or extraction, can prevent that liquid preparation etc. from leaking outside from depressed part, and can more firmly engage with syringe or connecting elements.

In addition, the gland main body also can replace cutting port part or jaws part by conical bore, and conical bore vertically extends the partly middle of gland main body, it is than an end of the minor diameter side towards the low surface of gland main body, therefore when the injection that is inserted into liquid preparation etc. when the gland main body is extracted out in the mouth, the clamp pressure that it produced can increase the sealing effectiveness of conical bore.When the front end of syringe or connecting elements partly was inserted in the conical bore of zone line of gland main body upper surface from the outside, the elastomer of position around conical bore can flexibly be out of shape and open, thereby can inject or extract out liquid preparation or other liquid.At this moment, the elastomer of position around conical bore can open downwards, and can closely contact the front end whole exterior circumferential surface partly of syringe or connecting elements, so can prevent liquid leakage closely.When the front end of syringe or connecting elements was partly pulled out, the elastomer of position around conical bore can bounce back into original state, and conical bore can be the state of sealing.And the clamp pressure of gland main body increases to the bottom gradually from the front end of syringe or connecting elements top partly, therefore when the front end of syringe or connecting elements partly is inserted in the conical bore, can prevent leaking outside of liquid preparation etc.In addition, see through and confirm valve, also can increase clamp pressure, can improve the effect of sealing.

The gland main body also can dispose an air displacement pipe, and the air displacement pipe extends vertically up to the inside of gland main body.Therefore when such as being that the liquid of liquid preparation is when the liquid preparation bottle is extracted out, or will be injected in the liquid preparation bottle time, see through the air displacement pipe and can make extraneous air enter in the liquid preparation bottle or the air in the liquid preparation bottle can be discharged, so can inject or extract out liquid preparation etc. smooth-goingly.

The air displacement pipe is made of a tubular element that is filled with water-repellent substance, and wherein water-repellent substance is fair passes through wherein with air, and does not allow moisture to pass through.So, the air displacement pipe can prevent entering of liquid or flow out, and only allows air to flow into or flow out.

And water-repellent substance can also intercept antibacterial, therefore can prevent that airborne antibacterial from entering into inside by the air displacement pipe from the outside.

The gland main body disposes a vertical perforation, one air displacement pipe is inserted in the vertical perforation, and the length of air displacement pipe is less than the length of vertical perforation, therefore with regard to its length, can have a residual quantity between air displacement pipe and the vertical perforation, and an end of air displacement pipe can with the upper surface flush of gland main body, when the injection that is installed to liquid preparation or similar object when the gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of gland main body, the elastic force that clamp pressure produced, and the stress effect of pushing, the elastomer meeting that downside is managed in vertical perforation ambient air displacement in the feasible position of meeting is closed, and the pattern of similar lip, and can form an affirmation valve, leak outside to prevent liquid preparation or similar material.Constituted by position elastomer around below the air displacement pipe in the perforation of gland main body owing to confirm valve, and can be prevented that the liquid of inside from escaping to the outside by the air displacement pipe, only allows air to enter from the outside.

In addition, also can insert the function that the air displacement pipe replaces perforation, also can dispose a hole with bottom such as the bottom of gland main body, and the air displacement pipe can insert and is set in this hole, in the hole bottom is that cutting part or duck eye are set, cutting part or duck eye vertically extend in the bottom of hole, when the injection that is installed to liquid preparation etc. when the gland main body is extracted out and mouthful is gone up, owing to be subjected to the clamp pressure that elastomer produced of gland main body and the effect that stress is pushed, can make opening structure produce clamp pressure.So, the position is below the air displacement pipe] opening structure can allow the air to pass through, and prevent that liquid from passing through.

According to another preferred embodiment of the present invention, the injection of liquid preparation etc. is extracted mouth sealing device out and is also comprised an annular recess, the position is around the upper surface of gland main body, and the gland main body is the elastomer with cutting port part or jaws part, and wherein cutting port part or jaws part vertically run through the zone line of gland main body.In the injection that one upper shield can make the gland main body be fixed to liquid preparation etc. is extracted out mouthful, upper shield has a circular protrusion partly, circular protrusion volume partly is greater than the volume of annular recess, the position of circular protrusion part and the position tabling of annular recess, and circular protrusion partly can closely be inserted in the annular recess, thereby produce a clamp pressure on cutting port part or jaws part, so can seal cutting port part or jaws part.Because the circular protrusion of upper shield partly can closely be tucked in the annular recess of gland main body, therefore the gland main body of position around annular recess can produce stress, see through push effect and elastic force and can produce clamp pressure, and seal up cutting port part or jaws part at cutting port part or jaws part.Therefore, in aforesaid embodiment, when not applying pressure to the exterior circumferential part of gland main body, the gland main body also can produce clamp pressure, thereby has the function of sealing.

The front end of syringe or connecting elements partly more is provided with the ring-like anti-projection that pitches, in the time of in the front end of syringe or connecting elements partly is inserted into the cutting port part of gland main body, in jaws part or the conical bore, the front end that the ring-like anti-projection that pitches can stop syringe or connecting elements partly and prevent that it from coming off.Therefore, the front end that can keep syringe or connecting elements stabile and for a long time partly inserts connection status.

According to another preferred embodiment of the present invention, mouth sealing device is extracted in the injection of a kind of liquid preparation etc. out, comprise a gland main body, in the time of in the injection that the gland main body is pressed into liquid preparation etc. is extracted out mouthful, having resistance produces, and after in the injection that the gland main body is pressed into liquid preparation etc. is extracted out mouthful, pass through cap, in the injection that the gland main body can be fixed on liquid preparation etc. is extracted out mouthful, generation with the phenomenon that prevents to get loose, the gland main body has a flat surfaces, the position is at the upper surface of gland main body, and the gland main body also has a depressed part, the position is at the lower surface of gland main body, the middle part of gland main body has a cutting port part, jaws part or conical bore, flat surfaces has a circular protrusion partly, the position is at cutting port part, the periphery of jaws part or conical bore, and can cooperate with the middle hole of cap, the flat surfaces of circular protrusion inboard and the ring-shaped protrusion flat surfaces of side especially flush, the inner circumferential surface of the middle hole of lid cover is the inclined surface of similar rounding taper hole, and inclined surface is smooth engaging each other with the flat surfaces of the circular protrusion part inboard of gland main body upside.When syringe or connecting elements during in injection, liquid medicine or similarly material be stacked under the situation of upper surface of gland main body, can utilize absorbent cotton, gauze or similar material, just liquid medicine or similar material are wiped away easily; Or will sterilize the time, utilize absorbent cotton, gauze or similarly material immerse after the sterilised liq, can be easily with the upper surface sterilization of gland main body, wherein sterilised liq can be an ethanol.

The partly inboard flat surfaces of circular protrusion is higher than the position at this ring-shaped protrusion flat surfaces of side especially, and the partly inboard flat surfaces of circular protrusion is the form of outstanding arc-shaped surface.Therefore when syringe or connecting elements during in injection, liquid medicine or similarly material be stacked under the situation of upper surface of gland main body, utilize absorbent cotton, gauze or similar material, can more easily liquid medicine or similar material be wiped away; Or will sterilize the time, utilize absorbent cotton, gauze or similarly material immerse after the sterilised liq, can be easily with the upper surface sterilization of gland main body, wherein sterilised liq can be an ethanol.

The position is the pattern of similar circular-arc or taper inclined surface at the corner of the inner circumferential surface of depressed part and roof intersection.Because the inner circumferential surface of position in the depressed part of gland main body lower surface and the corner of roof intersection are circular-arc pattern, therefore in the time of in the front end of syringe or connecting elements partly is inserted into the cutting port part of gland main body or in the jaws part, the elastomeric pressure that rebounds can increase; In addition, by applying external pressure, also can increase the elastomeric pressure that rebounds; And also can avoid because elastomer that internal pressure caused to the phenomenon of upper process, so can increase the reliability that cutting port part, jaws part or conical bore seal.When the sealing effectiveness of cutting port part, jaws part or conical bore increased, the internal pressure that elastomer can bear also can improve.

The gland main body has a patchhole, and patchhole vertically extends through in the gland main body from the zone line of the upper surface of gland main body, and the front end of syringe or connecting elements partly can be inserted in and inserts in the hole.Also has an endless groove at patchhole, and two semicircle disk bodies can closely be seated in the endless groove, be combined into an independent disc, the similar cutting port part of composition surface between the two semicircle disk bodies or the function of jaws part, a valve film structural component like this also can closely be fixed in the endless groove.Therefore make the cutting port part of gland main body or the step of jaws part can be saved, and can utilize two semicircle disk bodies to replace it.

The gland main body has a patchhole, the patchhole position is at the zone line of the upper surface of gland main body, and the front end of syringe or connecting elements partly can be inserted in and inserts in the hole, patchhole or the position plastics inner sleeve in patchhole has a female thread groove, and syringe or connecting elements have an external screw thread convex ridge, external screw thread convex ridge position is on the front end part of syringe or connecting elements, so the external screw thread convex ridge can be engaged in the female thread groove, make syringe or connecting elements to link together, and can prevent that syringe or connecting elements and gland main body from getting loose with the gland main body.So, when the front end of syringe or connecting elements partly be inserted into insert in the hole or inner sleeve in when injecting or extract liquid preparation out, can prevent liquid preparation from insert in the hole or inner sleeve spill, and design by patchhole or inner sleeve, the front end that can stop syringe or connecting elements at any time partly be inserted into insert in the hole or inner sleeve in, and present the connection status that oneself button is held (self-hold).

The gland main body has a patchhole, the patchhole position is at the zone line of the upper surface of gland main body, and the front end of syringe or connecting elements partly can be inserted in and inserts in the hole, patchhole or the position plastics inner sleeve in patchhole has at least one first ring-type padlock partly, and syringe or connecting elements have one second ring-type padlock partly, second ring-type padlock part position is on the front end part of syringe or connecting elements, the first ring-type padlock like this partly can partly engage mutually with the second ring-type padlock, make syringe or connecting elements to link together, and can prevent that syringe or connecting elements and gland main body from getting loose with the gland main body.So, when the front end of syringe or connecting elements partly be inserted into insert in the hole or inner sleeve in when injecting or extract liquid preparation out, can prevent liquid preparation from insert in the hole or inner sleeve spill, and design by patchhole or inner sleeve, when the first ring-type padlock partly and the second ring-type padlock when partly engage mutually, the front end that can stop syringe or connecting elements partly insert in the hole or inner sleeve in mobile.Therefore when cutting port part or jaws part are in aperture position and sealing station, the front end of gland main body and syringe or connecting elements presents the self-connection status of holding of detaining between partly.

Cooperate icon will narrate embodiments of the invention.

Description of drawings

Figure 1A illustrates the plane graph according to the gland main body of first embodiment of the invention.

Figure 1B illustrates the profile according to the gland main body of first embodiment of the invention.

Fig. 1 C illustrates by cap and the gland main body is pressed into the profile that mixes in the ascending pipe.

Fig. 2 A illustrates the plane graph of revising the gland main body of pattern according to first embodiment.

Fig. 2 B illustrates the profile of revising the gland main body of pattern according to first embodiment.

Fig. 2 C illustrates by cap and the gland main body is pressed into the profile that mixes in the ascending pipe.

Fig. 3 A and Fig. 3 B illustrate by changing external pressure and put on the sketch map that area on the gland main body increases clamp pressure.

Fig. 4 A, Fig. 4 B and Fig. 4 C illustrate the shape sketch map of the jaws part of gland main body.

Fig. 5 A and Fig. 5 B illustrate plane graph and the profile according to the gland main body of another modification pattern of first embodiment respectively.

Before Fig. 5 C and Fig. 5 D illustrate respectively and reach, has the section enlarged diagram of the jaws part in V-type cross section, wherein the modification pattern of jaws part shown in Fig. 5 A and Fig. 5 B after applying clamp pressure.

Fig. 6 A and Fig. 6 B illustrate respectively according to a profile and a plane graph of revising the gland main body of pattern again.

Fig. 6 C illustrates conical bore generalized section partly when irritating mould.

Fig. 6 D illustrates conical bore generalized section partly when tempering next.

Fig. 6 E illustrates is having clamp pressure to make time spent conical bore section enlarged diagram partly.

Fig. 7 A, Fig. 7 B and Fig. 7 C illustrate the sketch map that the front end of syringe or connecting elements is partly partly opened conical bore, wherein the modification pattern of conical bore shown in Fig. 6 A and Fig. 6 B respectively.

Fig. 7 D, Fig. 7 E and Fig. 7 F are respectively the following view of Fig. 7 A, Fig. 7 B and Fig. 7 C.

Fig. 8 A and Fig. 8 B illustrate respectively when the front end of syringe or connecting elements partly also is not inserted in the conical bore of piston main body and be inserted in the conical bore of piston main body after operation chart, the modification pattern of conical bore shown in Fig. 6 A and Fig. 6 B wherein, and also have the ring-like anti-projection that pitches at the front end front end partly of syringe or connecting elements.

Fig. 9 A illustrates according to a profile of revising the gland main body of pattern again, and wherein the gland main body does not produce clamp pressure.

Fig. 9 B illustrates according to a profile of revising the gland main body of pattern again, and wherein the gland main body has produced clamp pressure.

Fig. 9 C illustrates the generalized section that the air displacement pipe is configured in the intravital modification pattern of gland master, and wherein the gland main body is revised the gland main body among Fig. 9 A freely.

Figure 10 A and Figure 10 B illustrate respectively cap according to second embodiment of the invention before being configured to the gland main body and after profile.

The gland main body that Figure 11 A illustrates according to third embodiment of the invention is configured to the profile that mixes in the ascending pipe.

Figure 11 B only illustrates the profile of gland main body.

Figure 12 A illustrates the gland main body of revising pattern according to the 3rd embodiment and is configured to the profile that mixes in the ascending pipe.

Figure 12 B only illustrates the profile of gland main body.

Figure 13 A illustrates according to another gland main body of revising pattern of the 3rd embodiment and is configured to the profile that mixes in the ascending pipe.

Figure 13 B only illustrates the profile of gland main body.

Figure 14 illustrates the generalized section of the pattern of revising according to first embodiment.

Figure 15 A is the following view of the modification pattern of gland main body among Figure 14.

Figure 15 B is the profile that the injection of liquid preparation etc. is extracted out mouthful.

Figure 16 A illustrates the generalized section of the pattern of revising according to first embodiment.

Figure 16 B illustrates the enlarged drawing of the cutting port part of gland main body.

Figure 17 A illustrates to Figure 17 E that other revises the generalized section of pattern according to first embodiment.

Figure 18 A, Figure 18 B and Figure 18 C illustrate the sketch map that the valve film is opened, and wherein the valve film is shown in Figure 17 A.

Figure 19 illustrates the generalized section according to another modification pattern of first embodiment.

Figure 20 A and Figure 20 B illustrate the profile of the valve film of another modification pattern of first embodiment, and Figure 20 A opens generalized section before for the valve film, and Figure 20 B opens generalized section afterwards for the valve film.

Figure 21 illustrates the generalized section of revising pattern again according to first embodiment.

Figure 22 illustrates the generalized section according to another modification pattern of first embodiment.

Figure 23 A illustrates the generalized section according to the another modification pattern of first embodiment.

Figure 23 B illustrates the generalized section when the valve film is opened.

Figure 23 C illustrates the schematic perspective view of valve film.

Figure 24 illustrates the bottle stopper generalized section of liquid preparation bottle.

Figure 25 illustrates the generalized section of known mixing ascending pipe.Label declaration

1: gland main body 1a: cutting port part

1a ': lip 1b: overhang

1c, 1d: depressed part 1c ': patchhole

1e: circular-arc lead angle 1f: jaws part

1g: conical bore 1h: perforation

1i: bottom 1j: hole with bottom

1k: the vertical partly 1m of cutting that extends: upper flange partly

1n: annular recess 1o: valve film

1p, 3a: the ring-type padlock is 1q partly: endless groove

1v, 1v ', 1v ": flat surfaces 1u, 6a: circular protrusion is partly

1u ': annular stepped is 1w partly: the circular-arc surface of projection

2: mix ascending pipe 2a, 21: inject and extract mouth out

2b: flange protrusions 3: front end partly

3 ': the ring-like anti-projection 3b that pitches: external screw thread convex ridge

4: air displacement pipe 4a: tubular element

4b: water-repellent substance 5: confirm valve

6,24,33: lid cover 6b: middle hole

6b ': inclined surface 7: plastics inner sleeve

7a: female thread groove 8a: semicircle disk body

D1: outer diameter D 2: internal diameter

P: pressure 20: bottle main body

22,32: rubber plug 23: the bottleneck flange

25: syringe 26: syringe needle

30:T type tube body 31: the bifurcated tubulose partly

The specific embodiment

Please refer to Figure 1A, Figure 1B and Fig. 1 C, the first embodiment of the present invention comprises a gland main body 1 (plug main body), and it is elastic cylindrical object.Gland main body 1 has a valve film 1o (valve membrane), the position is at the zone line of gland main body 1, and the zone line of valve film 1o has a cutting port part 1a (cut portion), when from the outside with the direction of radius, exert pressure P on gland main body 1 time, can make cutting port part 1a present the state of sealing.Gland main body 1 is an elastomer, and such as being rubber, and the cutting port part 1a of gland main body 1 is collinear pattern, and its bearing of trend extends at the zone line of gland main body 1.And, the outer diameter D 1 of gland main body 1 can be extracted mouthful inside diameter D 2 of 2a (injection and extraction port) out greater than injecting, therefore inject extraction mouthful 2a and can produce pressure gland main body 1, make gland main body 1 closely to be configured in and inject within the extraction mouthful 2a, so can produce a pressure of seizing on both sides by the arms at cutting port part 1a, and seal up cutting port part 1a, wherein inject and extract the usefulness of mouthful 2a out, extract mouthful 2a position out on the liquid medicine bottle or on the mixing ascending pipe and inject as injection or extraction liquid preparation etc.

Please refer to Fig. 2 A, Fig. 2 B and Fig. 2 C, it illustrates the structure-improved of first embodiment, and wherein the exterior circumferential of gland main body 1 partly has overhang 1b (convex portions), and its position is perpendicular to the bearing of trend of the cutting port part 1a of gland main body 1.

Gland main body 1 has a cyclic peripheral surface, and

depressed part

1c, 1d (recess) difference position is in the upper and lower side of the zone line of gland main body 1.The position is slightly less than the front end external diameter partly of syringe or connecting elements at the internal diameter of the depressed part 1c of upside.

As shown in Figure 2, for the front end that can make syringe or connecting elements partly is inserted into the position in the depressed part 1c of gland main body 1 upper surface, the porch of depressed part 1c can have a circular-arc lead angle 1e (rounded guide).

The position can be less than the front end length partly of syringe or connecting elements in the degree of depth of the depressed part 1c of gland main body 1 upper surface.And the bottom of depressed part 1c is smooth surface.

In Figure 1B and Fig. 1 C, the position can be equal to the internal diameter of position at the depressed part 1c of gland main body 1 upper surface at the internal diameter of the depressed part 1d of gland main body 1 lower surface.And in Fig. 2 B and Fig. 2 C, the position can be greater than the internal diameter of position at the depressed part 1c of gland main body 1 upper surface at the internal diameter of the depressed part 1d of gland main body 1 lower surface, and be circular-arc pattern between inner circumferential surface in the depressed part 1d and the end face.The purpose that is provided with of depressed part 1d is, when the front end of syringe or connecting elements partly inserts, can make the elastomer of position around the cutting port part 1a of gland main body 1 zone line be easier to flexibly be out of shape downwards, and in order to promote the sealing effectiveness of cutting port part 1a, therefore when usual the time, cutting port part 1a can't open, only when injecting or extract liquid preparation or its similar material out, cutting port part 1a just can open, and the shape of its depressed part 1d is shown in Fig. 2 A, Fig. 2 B and Fig. 2 C.Shape compared to the cutting port part 1a of Figure 1A, Figure 1B and Fig. 1 C, the depressed part 1d of Fig. 2 A, Fig. 2 B and Fig. 2 C, because depressed part 1d position has circular-arc part in the corner part, therefore elastomer can increase the ability of rebounding, so the position can increase in the elastomeric clamping strength of the relative both sides of cutting port part 1a, when its clamping strength heals when big, elastomeric internal pressure will heal greatly, so can promote the sealing effectiveness of cutting port part 1a, and when extracting syringe or connecting elements, elastomeric internal pressure must be overcome, therefore the resistance of pulling out can be increased.

Resin shape before gland main body 1 can utilize a mould to form in the mode of irritating film after gland main body 1 is made in the mode of irritating film, also will utilize cutter that are fit to produce cutting port part 1a.The rough internal diameter that equals the position at the depressed part 1c of gland main body 1 upper surface of the length of cutting port part 1a.

When the front end of syringe or connecting elements partly is inserted into the position in the depressed part 1c of gland main body 1 upper surface the time, can cause the flexiblely distortion downwards of elastomer of the relative both sides on cutting port part 1a next door, therefore the front end by syringe or connecting elements partly can make cutting port part 1a be the state of opening.Just can inject or extract out liquid this moment.When the front end of syringe or connecting elements partly is inserted in the cutting port part 1a, the front end of syringe or connecting elements peripheral outer surface partly can closely contact cutting port part 1a, also can closely contact simultaneously the inner circumferential surface of depressed part 1c, therefore can prevent the liquid leakage in ampoule or other the similar bottle.In addition, when the front end of syringe or connecting elements was partly pulled out, the elastomer around the cutting port part 1a can bounce back into original state, and seals up cutting port part 1a, can prevent the liquid leakage in ampoule or other the similar bottle.

Please refer to Figure 1B, next the equation of sealing cutting port part 1a will be described.Definition ψ is the internal diameter of gland main body 1, and T is vertical thickness, and P is an external pressure, and P1 is a clamp pressure, and E is a stress coefficient, and utilizes stress coefficient E, external pressure P can be converted to clamp pressure P1.Under classify its applied equation as:

T/ψ ^X＝E

E×P＝P1

Can learn by above equation,, can increase clamp pressure P1 by increasing external pressure P or stress coefficient E.

Fig. 3 A and Fig. 3 B illustrate the sketch map that increases clamp pressure by the external pressure receiving area that changes gland main body 1.The shape of the valve film 1o of gland main body 1 is shown in Fig. 3 A and Fig. 3 B, and when valve film 1o exterior circumferential vertical thickness partly is modified as greater than in the middle of the valve film 1o during partly vertical thickness, external pressure P and stress coefficient E can increase, so clamp pressure P1 can increase.As shown in Figure 3A, be the part of even vertical thickness partly in the middle of the valve film 1o of gland main body 1, and outer perimeter is for increasing the part of vertical thickness gradually.In addition, shown in Fig. 3 B, from partly increasing vertical thickness gradually partly in the middle of the valve film 1o of gland main body 1 to exterior circumferential.So, the clamp pressure P1 of Fig. 3 B can be greater than the clamp pressure P1 of Fig. 3 A.Yet the valve film 1o of gland main body 1 also can be other pattern.

Fig. 4 A, Fig. 4 B and Fig. 4 C illustrate jaws part 1f (slitportion) sketch map of the valve film 1o of gland main body 1, and it substitutes cutting port part 1a with jaws part 1f.Shown in Fig. 4 a, the formed opening of jaws part 1f is parallel to the vertical direction of the valve film 1o of gland main body 1.Moreover shown in Fig. 4 B and Fig. 4 C, the opening of the jaws part 1f of the valve film 1o of gland main body 1 is the cross sectional shape of inverted V-shape or is the cross sectional shape of V-shape, and the size of opening is being prolonged the vertical direction of gland main body 1 and increased gradually or dwindle.

Fig. 5 A and Fig. 5 B illustrate the another kind of modified version of first embodiment, and the jaws part 1f position with V-shape cross section opening is on the valve film 1o of gland main body 1.Fig. 5 C and Fig. 5 D illustrate the enlarged diagram of jaws part 1f.Please refer to Fig. 5 C, when external pressure did not also apply, the elastomeric external diameter of position around jaws part 1f was D1 '; And after external pressure applies, the elastomeric external diameter of position around jaws part 1f can be kept to D2 ', shown in Fig. 5 D, and the generation of external pressure is because exert pressure to gland main body 1, so be used to inject and the channel of liquid jet medicine etc. also can bear pressure, so can seal up jaws part 1f.D1 ' and D2 ' are proportional to the outer diameter D 1 and the D2 of whole gland main body 1.In addition, also has sealing situation shown in Fig. 5 C and Fig. 5 D at jaws part 1f parallel among Fig. 4 A and at the jaws part 1f that has the inverted V-shape cross section among Fig. 4 B.In addition, because the inner circumferential surface of depressed part 1d and the corner regions of roof intersection have circular-arc part, therefore elastomer can increase the ability of rebounding, can increase the resistance that the front end of syringe or connecting elements partly inserts this moment, and also can resist external pressure, simultaneously also can increase the resistance that syringe or connecting elements pull outward, this is because elastomeric internal pressure will prevent that syringe or connecting elements from dropping away.When the sealing effectiveness of jaws part 1f better the time, elastomeric internal pressure will heal greatly.

Fig. 6 A and Fig. 6 B illustrate the another kind of modified version of first embodiment, it replaces cutting port part 1a or jaws part 1f with conical bore 1g (conical hole), and conical bore 1g vertically extends the middle part of the valve film 1o of gland main body 1, it is than an end of the minor diameter side towards the low surface of gland main body 1, Fig. 6 A is a profile, and Fig. 6 B is a underside view.Fig. 6 C, Fig. 6 D and Fig. 6 E illustrate the enlarged diagram of conical bore 1g respectively.When making gland main body 1, conical bore 1g will do a little more greatly, shown in Fig. 6 C, and then carries out tempered processing technology, makes conical bore 1g can be shrunk to less diameter, forms closing state, shown in Fig. 6 D.Please refer to Fig. 6 D, when external pressure did not also apply, the elastomeric external diameter of position around conical bore 1g was D1 '; And after external pressure applies, the elastomeric external diameter of position around conical bore 1g can be kept to D2 ', shown in Fig. 6 E, and the generation of external pressure is because exert pressure to gland main body 1, so be used to inject and the channel of liquid jet medicine etc. also can bear pressure, so can seal up conical bore 1g.D1 ' and D2 ' are proportional to the outer diameter D 1 and the D2 of whole gland main body 1.In addition, in Fig. 6 A, because the inner circumferential surface of depressed part 1d and the corner regions of roof intersection have circular-arc part, therefore elastomer can increase the ability of rebounding, can increase the resistance that syringe or connecting elements (being illustrated in Fig. 7 B) front end insert this moment, and also can resist external pressure, also can increase the resistance that syringe or connecting elements pull outward simultaneously, this is because elastomeric internal pressure will prevent that syringe or connecting elements from dropping away.When the sealing effectiveness of conical bore 1g better the time, elastomeric internal pressure will heal greatly.

Fig. 7 A, Fig. 7 B and Fig. 7 C illustrate the continuous action sketch map of the gland main body among Fig. 6 A and Fig. 6 B, the front end that originates in syringe or connecting elements partly 3 is inserted among the conical bore 1g of gland main body 1, and the front end that ends at syringe or connecting elements partly 3 is pulled out from the conical bore 1g of gland main body 1.In addition, Fig. 7 D, Fig. 7 E and Fig. 7 F illustrate the following view of Fig. 7 A, Fig. 7 B and Fig. 7 C respectively.Please refer to Fig. 7 A, when the injection that is installed in liquid preparation or similar object when gland main body 1 is extracted out and mouthful to be gone up, gland main body 1 can be subjected to clamp pressure, wherein the direction of clamp pressure from exterior circumferential partly toward the centre partly, and gland main body 1 also can be subjected to the internal pressure of liquid preparation bottle or similar object, therefore can seal up conical bore 1g.Please refer to Fig. 7 B, when the front end part 3 of syringe or connecting elements is inserted into depressed part 1c, the elastomer of position around the conical bore 1g can be pushed and put in place in the depressed part 1c of the lower face side of gland main body 1, and elastomer can flexibly be out of shape, make and therefore can inject or extract out liquid preparation or similar material by the state that conical bore 1g becomes to open.At this moment, the elastomer of position around conical bore 1g can open downwards, and can closely contact the whole exterior circumferential surface of the front end part 3 of syringe or connecting elements, so can prevent liquid leakage closely.Please refer to Fig. 7 C, when the front end part 3 of syringe or connecting elements was pulled out, the elastomer of position around conical bore 1g can bounce back into original state, and conical bore 1g is the state of sealing, becomes the state as Fig. 7 A.The position can be greater than the internal diameter of position at the depressed part 1c of gland main body 1 upper surface at the internal diameter of the depressed part 1d of gland main body 1 lower surface, and because the inner circumferential surface of depressed part 1d and the corner of roof intersection partly are inclined surface, therefore elastomer can increase the ability of rebounding, can increase the resistance that the front end of syringe or connecting elements (being illustrated in Fig. 7 B) partly inserts this moment, and also can resist external pressure, simultaneously also can increase the resistance that syringe or connecting elements pull outward, this is because elastomeric internal pressure will prevent that syringe or connecting elements from dropping away.When the sealing effectiveness of conical bore 1g better the time, elastomeric internal pressure will heal greatly.

Fig. 8 A and Fig. 8 B illustrate a ring-like anti-projection 3 ' (annular slip-offpreventive projection) that pitches, wherein ring-like anti-3 ' front end in the front end part 3 of syringe or connecting elements of projection that pitch.Fig. 8 A illustrates in the front end of syringe or connecting elements 3 situations before being inserted among the conical bore 1g of the gland main body 1 shown in Fig. 6 A and Fig. 6 B partly, and Fig. 8 B illustrates in the front end of syringe or connecting elements 3 situations after being inserted among the conical bore 1g of the gland main body 1 shown in Fig. 6 A and Fig. 6 B partly.Please refer to Fig. 8 B, the ring-like anti-projection 3 ' that pitches protrudes in the front end part 3 of syringe or connecting elements, and can pass conical bore 1g, and arrives the back of conical bore 1g, so can hold the front end part 3 that holds syringe or connecting elements, prevent that syringe or connecting elements from getting loose.Must extract mouth out with the injection of liquid medicine bottle or mixing ascending pipe when the front end part 3 of syringe or connecting elements and engage a segment length during time, above-mentioned configuration is necessary.

Fig. 9 A illustrates the another kind of modified version of first embodiment, and wherein air displacement pipe 4 (airreplacement tube) extends vertically up among the gland main body 1.Air displacement pipe 4 is made of a tubular element 4a (pipe member) who is filled with water-repellent substance 4b (water repellent substance), and wherein water-repellent substance 4b is fair passes through wherein with air, and does not allow moisture to pass through.And water-repellent substance 4b can be suitable fiber material, and this fiber material must have filtering function, and water-repellent substance 4b also must intercept antibacterial and moisture.

Shown in Fig. 9 A, air displacement pipe 4 is inserted among the perforation 1h (through-hole) of gland main body 1, and the length of air displacement pipe 4 can be shorter than the length of perforation 1h, therefore with regard to its length, can have a residual quantity between air displacement pipe 4 and the perforation 1h, and an end of air displacement pipe 4 can with the upper surface flush of gland main body 1.When the injection that is installed in liquid preparation or similar object when gland main body 1 is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that gland main body 1 is produced, the elastic force that clamp pressure produced, and the stress effect of pushing, can make that an elastomer at perforation 1h ambient air displacement pipe 4 downsides can be closed, and the pattern of similar lip, and can form an affirmation valve 5 (check valve), leak outside to prevent liquid preparation or similar material.

Shown in Fig. 9 C, perforation 1h can be replaced by a hole 1j (bottomed hole) and the vertical cutting part 1k (vertically extending cut portion) that extends with bottom, wherein hole 1j has a bottom 1i (bottom), the position is at the lower position of hole 1j, and the vertical cutting part 1k that extends is produced under the bottom 1i of hole 1j by a cutter that is fit to.Air displacement pipe 4 can be inserted among the hole 1j, and when the injection that is installed in liquid preparation or similar object when gland main body 1 is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that gland main body 1 is produced, the elastic force that clamp pressure produced, and the stress effect of pushing, can prevent liquid preparation or similarly material leak outside.In addition, cutting part 1k also can replace by the produced aperture of a similar acicular drill bit.And perforation 1h or hole 1j just make during in molding simultaneously when gland main body 1.

Figure 10 A and Figure 10 B illustrate the second embodiment of the present invention, wherein the annular recess 1n in V-type cross section (annular concave groove) position is around gland main body 1 upper surface, and the circular protrusion that has a round cross section on the surface, inside of a lid cover 6 (cap) 6a (annular convex portion) partly, its relevant position is corresponding with annular recess 1n, and shown in Figure 10 B, circular protrusion partly 6a can press in the annular recess 1n, and so gland main body 1 can produce clamp pressure and seal up jaws part 1f.Annular recess 1n is the center with the jaws part 1f of gland main body 1, is surrounded on the periphery of jaws part 1f, and therefore the volume of circular protrusion part 6a can produce clamp pressure to gland main body 1 greater than the space of annular recess 1n.And circular protrusion part 6a and annular recess 1n also can be other patterns, are not limited to the pattern shown in Figure 10 A and Figure 10 B.In addition, the external diameter of gland main body 1 also not necessarily is greater than the internal diameter of the injection extraction mouth of liquid preparation or similar object.In addition, in Figure 10 A and Figure 10 B, because the inner circumferential surface of depressed part 1d and the corner regions of roof intersection have circular-arc part, therefore elastomer can increase the ability of rebounding, it is tighter to make that the front end of syringe or connecting elements is held this moment, and also can resist external pressure, also can increase the resistance that syringe or connecting elements pull outward simultaneously, this is because elastomeric internal pressure will prevent that syringe or connecting elements from dropping away.When the sealing effectiveness of jaws part 1f better the time, elastomeric internal pressure will heal greatly.And jaws part 1f can also replace by cutting port part 1a.

Figure 11 A and Figure 11 B illustrate the third embodiment of the present invention.Shown in Figure 11 A, in an embodiment of the present invention, utilize a default obstacle, gland main body 1 can be pressed to the injection that mixes ascending pipe 2 (mix injection tube) extracts out in mouthful 2a, and gland main body 1 can be fixed on injection by a lid cover 6 extracts out in mouthful 2a, in case detent plug bolt main body 1 gets loose.Shown in Figure 11 B, gland main body 1 has a flat surfaces 1v (flat surface), the position is at the upper surface of gland main body 1, and gland main body 1 also has a depressed part 1d, the position is at the lower surface of gland main body 1, and cutting port part 1a, jaws part 1f or conical bore 1g can be situated in the middle part of gland main body 1.And circular protrusion part 1u position is on the flat surfaces 1v of the upside of gland main body 1, and be positioned at cutting port part 1a, jaws part 1f or conical bore 1g around, and circular protrusion part 1u can cooperate with the middle hole 6b (central hole) of lid cover 6, the circular protrusion partly inboard of 1u is a flat surfaces 1v ', and this flat surfaces 1v ' flushes with the outer surface of circular protrusion part 1u.The inner circumferential surface of the middle hole 6b of lid cover 6 is the inclined surface 6b ' (taper surface) of similar rounding taper hole, and inclined surface 6b ' is smooth engaging each other with the flat surfaces 1v of the circular protrusion part 1u inside of gland main body 1 upside.So, when syringe or connecting elements during in injection, liquid medicine or similarly material be stacked under the situation of upper surface of gland main body 1, can utilize absorbent cotton, gauze or similar material, just liquid medicine or similar material are wiped away easily; Or will sterilize the time, utilize absorbent cotton, gauze or similarly material immerse after the sterilised liq, can be easily with the upper surface sterilization of gland main body 1, wherein sterilised liq can be an ethanol.

Figure 12 A and Figure 12 B illustrate the another kind of modified version of the 3rd embodiment, and the form of gland main body 1 and aforesaid embodiment are identical, only narrate different parts at this.Shown in Figure 12 B, gland main body 1 has a flat surfaces 1v, and the position is at the upper surface of gland main body 1, and with an annular stepped partly 1u ' (annular stepped portion) replace circular protrusion 1u partly shown in Figure 11 A and Figure 11 B.At the inboard flat surfaces iv of annular stepped part 1u ' " can be higher than the flat surfaces 1v of position in the outside.Shown in Figure 12 A, utilize a default obstacle, gland main body 1 can be pressed to the injection that mixes ascending pipe 2 extracts out in mouthful 2a, and gland main body 1 can be fixed on injection by a lid cover 6 extracts out in mouthful 2a, at this moment, middle flat surfaces 1v " can protuberance; so when syringe or connecting elements during in injection; liquid medicine or similarly material be stacked under the situation of upper surface of gland main body 1; can utilize absorbent cotton, gauze or similar material, just liquid medicine or similar material be wiped away easily; Or will sterilize the time, utilize absorbent cotton, gauze or similarly material immerse after the sterilised liq, can be easily with the upper surface sterilization of gland main body 1, wherein sterilised liq can be an ethanol.

Figure 13 A and Figure 13 B illustrate the another kind of modified version of the 3rd embodiment, and wherein the form shown in the form of gland main body 1 and Figure 11 A and Figure 11 B is identical, only narrates different parts at this.Shown in Figure 13 B, gland main body 1 has a flat surfaces 1v, the position is at the upper surface of gland main body 1, and with an annular stepped partly 1u ' (annular stepped portion) replace circular protrusion 1u partly shown in Figure 11 A and Figure 11 B, annular stepped partly the inboard of 1u ' be the circular-arc surperficial 1w of a projection (convex arcuate surface).As shown in FIG. 13A, utilize a default obstacle, gland main body 1 can be pressed to the injection that mixes ascending pipe 2 extracts out in mouthful 2a, and gland main body 1 can be fixed on injection by a lid cover 6 extracts out in mouthful 2a, at this moment, the circular-arc surperficial 1w of projection can swell more, so when syringe or connecting elements during in injection, liquid medicine or similarly material be stacked under the situation of upper surface of gland main body 1, can utilize absorbent cotton, gauze or similar material, just liquid medicine or similar material be wiped away easily; Or will sterilize the time, utilize absorbent cotton, gauze or similarly material immerse after the sterilised liq, can be easily with the upper surface sterilization of gland main body 1, wherein sterilised liq can be an ethanol.

At Figure 11 in Figure 13, the position in the purpose that is provided with of the depressed part 1d of gland main body 1 downside is, when the front end of syringe or connecting elements partly inserts, can make the position be easier to flexibly be out of shape downwards at cutting port part 1a, the jaws part 1f of gland main body 1 zone line or the elastomer around the conical bore 1g.In order to promote tightness, to prevent having unexpected opening to produce at ordinary times, only in injection or extraction liquid preparation etc., therefore the inner circumferential surface of depressed part 1d and the corner regions of roof intersection can be designed to have circular-arc part, so elastomer can increase the ability of rebounding, can increase the resistance that the front end of syringe or connecting elements partly inserts this moment, and also can resist external pressure, simultaneously also can increase the resistance that syringe or connecting elements pull outward, this is because elastomeric internal pressure will prevent that syringe or connecting elements from dropping away.When the sealing effectiveness of cutting port part 1a, jaws part 1f or conical bore 1g better the time, elastomeric internal pressure will heal greatly.And jaws part 1f also can replace by cutting port part 1a.In the embodiment of Figure 11 to Figure 13, have more than and be applied to mix on the ascending pipe, also can be applied on other the bottle, such as being the liquid preparation bottle.

Figure 14 illustrates the another kind of modified version of first embodiment, wherein when gland main body 1 presses to liquid also the injection of medicament or other material is extracted out in mouthful 2a, and gland main body 1 has partly 1m (upper flange potion) of a upper flange, utilize lid cover 6 upper flange part 1m can be pressed onto on the flange protrusions 2b (flange projection), its above-mentioned member is formed by the elastic material manufacturing, such as being rubber.And the position can be deepened at the depressed part of the zone line of gland main body 1 upper surface, to form a patchhole 1c ' (insertion hole), can hold the front end part 3 of syringe or connecting elements.Between the central depression 1d of gland main body 1 lower surface, and valve film 1o has a cutting port part 1a in patchhole 1c ' and position in valve film 1o position, and the position is at the zone line of valve film 1o.

Shown in Figure 15 A, overhang 1b position is on the exterior circumferential surface of gland main body 1, and the position of overhang 1b is perpendicular to the bearing of trend of the cutting port part 1a of gland main body 1, and so the design of overhang 1b can increase the clamp pressure of cutting port part 1a.Please refer to Figure 15 B, the external diameter of gland main body 1 can be extracted the internal diameter of mouthful 2a greater than the injection of liquid preparation etc. out, therefore injects to extract mouthful 2a out and can produce pressure to gland main body 1, make gland main body 1 closely to be configured in to inject to extract out within mouthful 2a.

Figure 16 A illustrates the another kind of modified version of first embodiment, wherein in sealing in order to increase the contact area of cutting port part 1a, cutting port part 1a can be designed to irregular shape, that is the cutting port part 1a width that prolonging valve film 1o presents the shape of fold.Figure 16 B is the enlarged drawing of cutting port part 1a, and wherein solid line is that the fold type is irregularly shaped, and dotted line is that undaform is irregularly shaped.Yet cutting port part 1a also can be linear type, square crossing type, fold type, undaform, irregularly shaped or other pattern.

Figure 17 A illustrates other modified version of first embodiment respectively to Figure 17 E.Wherein, the valve film shown in aforesaid Figure 14 A and Figure 16 A is smooth kenel, and the valve film 1o of the gland main body 1 shown in Figure 17 A is the pattern of projection, and it can resist internal pressure; Valve film 1o shown in Figure 17 B is the pattern of depression, and it can resist external pressure; Valve film 1o shown in Figure 17 C is the pattern of two projections, and it can resist outside and internal pressure; Valve film 1o shown in Figure 17 D is the pattern of outside flat internal projection, and it can resist internal pressure; Valve film 1o shown in Figure 17 E is the pattern of interior portion flattening exterior protrusions, and it can resist external pressure.

Figure 18 A, Figure 18 B and Figure 18 C illustrate the action sketch map that the valve film 1o of Figure 17 A opens, wherein when the front end part 3 of syringe or connecting elements is inserted into the patchhole 1c ' of gland main body 1, can make the internal pressure of patchhole 1c ', and cutting port part 1a can begin to open, shown in Figure 18 B.When the front end part 3 of syringe or connecting elements is more in depth inserted, partly 3 can push valve film 1o open by the front end of syringe or connecting elements, make cutting port part 1a present the state of complete opening, shown in Figure 18 C.At this moment, just can inject or extract out liquid preparation or similar material.Afterwards, when the front end part 3 of syringe or connecting elements will be extracted from the patchhole 1c ' of gland main body 1, can make cutting port part 1a be sealed by the negative pressure in rebound strength and the patchhole 1c ' of valve film 1o.And Figure 10 duplicates with aforesaid mode to the action that the valve film 1o of embodiment shown in Figure 16 opens and closes.

Figure 19 illustrates the another kind of modified version of first embodiment, and wherein lip 1a ' (1ipportions) is respectively formed on the inner surface and outer surface of joint of cutting port part 1a, with the sealing strength of the cutting port part 1a that increases valve film 1o.

Figure 20 A and Figure 20 B illustrate the valve film 1o opening action sketch map of the another kind of modified version of first embodiment, wherein the inner surface of the patchhole 1c ' of gland main body 1 has partly 1p (annular locking portions) of more than one ring-type padlock, wherein in Figure 20 A and Figure 20 B, ring-type padlock partly 1p is two.And the front end of syringe or connecting elements part 3 has partly 3a of single ring-type padlock, must match with the ring-type padlock part 1p of patchhole 1c ' in its position.The cooperation partly of these ring-type padlocks can make gland main body 1 and syringe or connecting elements be mutually locked, in case detent plug bolt main body 1 gets loose mutually with syringe or connecting elements.Shown in Figure 20 A, when carrying out the phase I of padlock action, cutting port part 1a is a closing state, and the front end of gland main body 1 can block mutually with syringe or connecting elements, and link together, can prevent that so liquid preparation from spilling from patchhole 1c '.Shown in Figure 20 B, when carrying out the second stage of padlock action, cutting port part 1a can become the state of unlatching, and gland main body 1 can partly 3 be blocked mutually with the front end of syringe or connecting elements, and the state that maintenance connects, so injection that can be stable or extract liquid preparation out, and can prevent that liquid preparation from spilling from patchhole 1c '.

Figure 21 illustrates the another kind of modified version of first embodiment, wherein also dispose a plastics inner sleeve 7 (inner sleeve of plastic) on the inner surface of the patchhole 1c ' of gland main body 1, can improve the degree of lubrication of patchhole 1c ' and the degree of abrasion resisting, wherein the front end of syringe or connecting elements partly 3 can be inserted among the patchhole 1c '.

Figure 22 illustrates the another kind of modified version of first embodiment, and wherein plastics inner sleeve 7 can cooperate with the patchhole 1c ' of gland main body 1, and the inside of plastics inner sleeve 7 also has a female thread groove 7a (internal thread groove).In addition, the front end of syringe or connecting elements part 3 has external screw thread convex ridge 3b (external thread ridge), and wherein the position of external screw thread convex ridge 3b is corresponding with the position of female thread groove 7a.When external screw thread convex ridge 3b and female thread groove 7a blocked, the front end that can make gland main body 1 and syringe or connecting elements partly 3 was connected.So injection that can be stable or extract liquid preparation out, and can prevent that liquid preparation from spilling from patchhole 1c '.In addition, the design of plastics inner sleeve 7 also can be saved, and female thread groove 7a directly is produced on the inner surface of patchhole 1c ' of gland main body 1.

Figure 23 A, Figure 23 B and Figure 23 C illustrate the another kind of modified version of first embodiment, wherein the patchhole 1c ' of gland main body 1 is a perforation, and patchhole 1c ' also has an endless groove 1q (annular groove), and endless groove 1q position is in the bosom of patchhole 1c '.In addition, two semicircle disk body 8a (half disks) can closely be seated among the endless groove 1q, are combined into an independent disc, and form a valve film 1o, and wherein semicircle disk body 8a is made by elastic material, such as being rubber.In this modified version, when two semicircle disk body 8a were placed among the endless groove 1q, therefore the function class of the composition surface between two semicircle disk body 8a was made the step of the cutting port part 1a of gland main body 1 and can be saved like cutting port part 1a.In addition, in this modified version, can dispose plastics inner sleeve 7, and also can save plastics inner sleeve 7.

The narration of embodiments of the invention and modified version is so far, yet application of the present invention is not to be defined in this, and embodiment and modified version be when can doing a little change and retouching, and protection scope of the present invention defines and is as the criterion when looking claims.For instance, gland main body in each embodiment of the present invention and modified version can utilize the mode of pressing to press to, and extracts out mouthful such as the injection that is liquid preparation bottle, liquid preparation vessel, mixes the liquid preparation of ascending pipe or the object similar with it.In addition, the lid cover can optionally use.In addition, the position can be made into the pattern of similar taper at the depressed part 1c inner surface of the upper surface of gland main body 1, and partly 3 shape is consistent with the front end of syringe or connecting elements; Moreover the inner surface of patchhole 1c ' also can be made into the pattern of similar taper, and its shape is the same with the shape of the front end part 3 of syringe or connecting elements.The front end that so can promote syringe or connecting elements partly 3 with the inner surface of depressed part 1c or patchhole 1c ' between seal degree, therefore when injecting or extracting liquid preparation out, it is next to prevent that liquid preparation from spilling.In addition, if the inner surface of depressed part 1c or patchhole 1c ' also disposes an annular projection, the pattern of similar scarf, the front end that also can promote syringe or connecting elements partly 3 and the inner surface of depressed part 1c or patchhole 1c ' between seal degree.In addition, the present invention also can be applied to other liquid, and is not to be limited to liquid preparation.In addition, utilize an adapter that liquid is injected efficiently or extract out, and adapter has and the front end of syringe 3 the same connecting channels partly.

Claims

1, mouth sealing device is extracted in the injection of a kind of liquid preparation etc. out, it is characterized in that: comprise a gland main body, this gland main body is similar elastomer cylindraceous, this gland main body has a valve film, this valve film position is at the zone line of this gland main body, and this valve film has and is selected from by a cutting port part, a kind of structure in the group that one jaws part and a conical bore are formed, this cutting port part, jaws part or conical bore position are at the zone line of this valve film, so when applying an external pressure on this gland main body the time from the outside with the direction of radius, this cutting port part, jaws part or conical bore can produce a clamp pressure, can make this cutting port part by this clamp pressure, jaws part or conical bore present the state of sealing.

2, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: in the time of in the injection that this gland main body is configured to a liquid preparation etc. is extracted out mouthful, can produce this external pressure.

3, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: the internal diameter that the external diameter of this gland main body can be extracted out mouthful greater than the injection of a liquid preparation etc., in the time of so in the injection that this gland main body will be tucked into this liquid preparation etc. is extracted out mouthful, have the resistance generation.

4, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: this gland main body also has an overhang, this overhang position is in the periphery of this gland main body, and perpendicular to the bearing of trend of this cutting port part or this jaws part length.

5, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: when when irritating this gland main body of molded work, this jaws part of this gland main body just completes, and this jaws part is the kenel of an elongated opening, and this jaws part can vertically run through this gland main body.

6, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, and it is characterized in that: the formed long strip type opening of this jaws part is parallel to the vertical direction of this gland main body.

7, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: the formed long strip type opening of this jaws part, its cross sectional shape is the shape of V-shape and inverted V-shape, either-or, and the size of this long strip type opening is being prolonged the vertical direction of this gland main body and is increased gradually and dwindle either-or.

8, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: when making this conical bore, this conical bore has than an end position of the minor diameter side at the lower surface of this gland main body.

9, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, and it is characterized in that: the thickness of the peripheral region of this gland main body is greater than the thickness of the zone line of this gland main body.

10, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: the vertical thickness of the zone line of this gland main body is for uniformly, and the vertical thickness of the peripheral region of this gland main body can increase gradually.

11, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: the vertical thickness of this gland main body increases toward the peripheral region gradually from middle zone.

12, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: this cutting port part that partly is tucked into this gland main body when a front end of a syringe or connecting elements, in the time of in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can flexibly be out of shape and open, when this front end of this syringe or connecting elements partly from this cutting port part of this gland main body, when extracting in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can bounce back into original state and present the state of sealing.

13, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: a syringe or connecting elements have a ring-like anti-projection that pitches, this ring-like anti-projection position front end part that pitches at this syringe or connecting elements, so when this front end of this syringe or connecting elements partly is tucked in this cutting port part, this jaws part or this conical bore of this gland main body, this ring-like anti-projection that pitches can stop this front end part of this syringe or connecting elements, pitches to prevent this syringe or connecting elements.

14, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole or a plastics inner sleeve that embeds in this patchhole have a female thread groove, and this front end of this syringe or connecting elements partly has an external screw thread convex ridge, so this external screw thread convex ridge can be engaged in this female thread groove, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

15, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole or a plastics inner sleeve that embeds in this patchhole have at least one first ring-type padlock partly, and have one second ring-type padlock partly on this front end part of this syringe or connecting elements, so this first ring-type padlock partly can partly engage mutually with this second ring-type padlock, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

16, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: the upper surface zone line of this gland main body and lower surface zone line both or one of them are formed with depressed part.

17, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 16 etc. out, it is characterized in that: the position at the diameter of this depressed part of this gland main body lower surface greater than the diameter of position at this depressed part of this gland main body upper surface, and the position in this depressed part of this gland main body lower surface inner circumferential surface and the corner of roof intersection be circular-arc pattern.

18, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 16 etc. out, it is characterized in that: the position has a patchhole at this depressed part of this gland main body upper surface, and the diameter of this patchhole is slightly less than the front end external diameter partly of a syringe or connecting elements.

19, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 16 etc. out, it is characterized in that: the position has a circular protrusion partly at this depressed part of this gland main body upper surface, and this circular protrusion internal diameter partly is slightly less than the front end external diameter partly of a syringe or connecting elements.

20, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, and it is characterized in that: this gland main body disposes an air displacement pipe, and this air displacement pipe extends vertically up to the inside of this gland main body.

21, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: this gland main body disposes a vertical perforation, one air displacement pipe is inserted in this vertical perforation, and the length of this air displacement pipe is less than the length of this vertical perforation, therefore with regard to its length, can have a residual quantity between the vertical perforation of this air displacement pipe with this, and an end of this air displacement pipe can with the upper surface flush of this gland main body, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body, the elastic force that clamp pressure produced, and the stress effect of pushing, can make that the elastomer of this air displacement pipe downside of position around this vertical perforation can be closed, and the pattern of similar lip, and can form one and confirm valve, leak outside to prevent liquid preparation or similar material.

22, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 20 etc. out, it is characterized in that: this gland main body disposes a hole, this hole has a bottom, the position is in the bottom of this hole, and this air displacement pipe can be inserted in this hole, this gland main body has an opening structure, this opening structure is selected from a kind of structure in the group that is made up of a cutting part and a duck eye, this opening structure vertically extends in the bottom of this hole, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body and the effect that stress is pushed, can make this opening structure produce a clamp pressure.

23, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 20 etc. out, it is characterized in that: this air displacement pipe comprises a tubular element, and this tubular element is filled with a water-repellent substance, and wherein this water-repellent substance allows air to pass through wherein, and does not allow moisture to pass through.

24, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 23 etc. out, and it is characterized in that: this water-repellent substance can also intercept antibacterial.

25, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 1 etc. out, it is characterized in that: a valve film structural component is made of two semicircle disk bodies, it forms an independent disc in conjunction with meeting, this valve film structural component can closely be seated in the zone line of this gland main body, the function class of the composition surface between this two disc is like the function of this aperture member, and this valve film structural component is made by elastic material, and can with this gland body portion from.

26, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: in the time of in the injection that this gland main body is configured to a liquid preparation etc. is extracted out mouthful, can produce this external pressure.

27, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: the internal diameter that the external diameter of this gland main body can be extracted out mouthful greater than the injection of a liquid preparation etc., when so the injection that will be tucked into this liquid preparation etc. when this gland main body is extracted out in the mouth, can produce resistance.

28, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: this gland main body also has an overhang, this overhang position is in the periphery of this gland main body, and perpendicular to the bearing of trend of this cutting port part, jaws part or conical bore length.

29, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: this cutting port part that partly is tucked into this gland main body when a front end of a syringe or connecting elements, in the time of in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can flexibly be out of shape and open, when this front end of this syringe or connecting elements partly from this cutting port part of this gland main body, when extracting in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can bounce back into original state and present the state of sealing.

30, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: a syringe or connecting elements have a ring-like anti-projection that pitches, this ring-like anti-projection position front end part that pitches at this syringe or connecting elements, so partly be tucked into this cutting port part of this gland main body when this front end of this syringe or connecting elements, in the time of in this jaws part or this conical bore, this front end of this syringe or connecting elements partly can run through this cutting port part by this gland main body, this jaws part or this conical bore, to this cutting port part, the back of this jaws part or this conical bore, and this ring-like anti-projection that pitches can snap into this cutting port part, pitch to prevent this syringe or connecting elements in the back of this jaws part or this conical bore.

31, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole and a plastics inner sleeve that embeds in this patchhole have a female thread groove, and this front end of this syringe or connecting elements partly has an external screw thread convex ridge, so this external screw thread convex ridge can be engaged in this female thread groove, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

32, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole and a plastics inner sleeve that embeds in this patchhole have at least one first ring-type padlock partly, and this front end of this syringe or connecting elements partly has one second ring-type padlock partly, so this first ring-type padlock partly can partly engage mutually with this second ring-type padlock, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

33, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, it is characterized in that: the upper surface zone line of this gland main body and lower surface zone line both or one of them are formed with depressed part.。

34, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 33 etc. out, it is characterized in that: the position has a patchhole at this depressed part of this gland main body upper surface, and the diameter of this patchhole is slightly less than the front end external diameter partly of a syringe or connecting elements.

35, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 33 etc. out, it is characterized in that: the position has a circular protrusion partly at this depressed part of this gland main body upper surface, and this circular protrusion internal diameter partly is slightly less than the front end external diameter partly of a syringe or connecting elements.

36, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 25 etc. out, and it is characterized in that: this gland main body disposes an air displacement pipe, and this air displacement pipe extends vertically up to the inside of this gland main body.

37, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 36 etc. out, it is characterized in that: this gland main body disposes a vertical perforation, one air displacement pipe is inserted in this vertical perforation, and the length of this air displacement pipe is less than the length of this vertical perforation, therefore with regard to its length, can have a residual quantity between the vertical perforation of this air displacement pipe with this, and an end of this air displacement pipe can with the upper surface flush of this gland main body, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body, the elastic force that clamp pressure produced, and the stress effect of pushing, can make that the elastomer of this air displacement pipe downside of position around this vertical perforation can be closed, and the pattern of similar lip, and can form one and confirm valve, leak outside to prevent liquid preparation or similar material.

38, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 36 etc. out, it is characterized in that: this gland main body disposes the hole with bottom, this air displacement pipe can be inserted in this hole, this hole bottom has a kind of structure that is selected from the group that is made up of a cutting part and a duck eye, this cutting part and this duck eye vertically extend in the bottom of this hole, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body and the effect that stress is pushed, can make this cutting part and this duck eye produce a clamp pressure.

39, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 36 etc. out, it is characterized in that: this air displacement pipe comprises a tubular element, and this tubular element is filled with a water-repellent substance, and wherein this water-repellent substance is fair passes through wherein with air, and does not allow moisture to pass through.

40, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 39 etc. out, and it is characterized in that: this water-repellent substance can also intercept antibacterial.

41, mouth sealing device is extracted in the injection of a kind of liquid preparation etc. out, comprise a gland main body, this gland main body is similar elastomer cylindraceous, this gland main body has a valve film, this valve film position is at the zone line of this gland main body, and this valve film has a cutting port part that is selected from by strip, a kind of structure in the group that one jaws part and a conical bore are formed, this cutting port part, this jaws part or this conical bore vertically run through this valve film, and this cutting port part, this jaws part or this conical bore position are at the zone line of this valve film, this gland main body has an annular recess, the position is around the upper surface of this gland main body, in the injection that one upper shield can make this gland main body be fixed to a liquid preparation etc. is extracted out mouthful, this upper shield has a circular protrusion partly, this circular protrusion volume partly is greater than the volume of this annular recess, match with the position of this annular recess in this circular protrusion position partly, and this circular protrusion partly can closely be inserted in this annular recess, thereby produce a clamp pressure to this cutting port part, on this jaws part or this conical bore, so can seal this cutting port part, this jaws part or this conical bore.

42, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, and it is characterized in that: this gland main body disposes an air displacement pipe, and this air displacement pipe extends vertically up to the inside of this gland main body.

43, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, it is characterized in that: this gland main body disposes a vertical perforation, one air displacement pipe is inserted in this vertical perforation, and the length of this air displacement pipe is less than the length of this vertical perforation, therefore with regard to its length, can have a residual quantity between the vertical perforation of this air displacement pipe with this, and an end of this air displacement pipe can with the upper surface flush of this gland main body, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body, the elastic force that clamp pressure produced, and the stress effect of pushing, can make that the elastomer of this air displacement pipe downside of position around this vertical perforation can be closed, and the pattern of similar lip, and can form one and confirm valve, leak outside to prevent liquid preparation or similar material.

44, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 42 etc. out, it is characterized in that: this gland main body disposes the hole with bottom, this air displacement pipe can be inserted in this hole, this hole bottom has a kind of structure that is selected from the group that is made up of a cutting part and a duck eye, this cutting part and this duck eye vertically extend in the bottom of this hole, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body and the effect that stress is pushed, can make this cutting part and this duck eye produce a clamp pressure.

45, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 42 etc. out, it is characterized in that: this air displacement pipe comprises a tubular element, and this tubular element is filled with a water-repellent substance, and wherein this water-repellent substance is fair passes through wherein with air, and does not allow moisture to pass through.

46, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 45 etc. out, and it is characterized in that: this water-repellent substance can also intercept antibacterial.

47, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, it is characterized in that: this cutting port part that partly is tucked into this gland main body when a front end of a syringe or connecting elements, in the time of in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can flexibly be out of shape and open, when this front end of this syringe or connecting elements partly from this cutting port part of this gland main body, when extracting in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can bounce back into original state and present the state of sealing.

48, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, it is characterized in that: a syringe or connecting elements have a ring-like anti-projection that pitches, this ring-like anti-projection position front end part that pitches at this syringe or connecting elements, so when this front end of this syringe or connecting elements partly is tucked in this cutting port part, this jaws part or this conical bore of this gland main body, this ring-like anti-projection that pitches can stop this front end part of this syringe or connecting elements, pitches to prevent this syringe or connecting elements.

49, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole and a plastics inner sleeve that embeds in this patchhole have a female thread groove, and this front end of this syringe or connecting elements partly has an external screw thread convex ridge, so this external screw thread convex ridge can be engaged in this female thread groove, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

50, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 41 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole and a plastics inner sleeve that embeds in this patchhole have at least one first ring-type padlock partly, and this front end of this syringe or connecting elements partly has one second ring-type padlock partly, so this first ring-type padlock partly can partly engage mutually with this second ring-type padlock, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

51, mouth sealing device is extracted in the injection of a kind of liquid preparation etc. out, it is characterized in that: comprise a gland main body, in the time of in the injection that this gland main body is pressed into a liquid preparation etc. is extracted out mouthful, having resistance produces, and after in the injection that this gland main body is pressed into this liquid preparation etc. is extracted out mouthful, by a cap, in the injection that this gland main body can be fixed on this liquid preparation etc. is extracted out mouthful, generation with the phenomenon that prevents to get loose, this gland main body 1 has a flat surfaces, the position is at the upper surface of this gland main body, and this gland main body also has a depressed part, the position is at the lower surface of this gland main body, and this valve film has and is selected from by a cutting port part, a kind of structure in the group that one jaws part and a conical bore are formed, this cutting port part, this jaws part or this conical bore position are in the middle part of this gland main body, this flat surfaces has a circular protrusion partly, the position is at this cutting port part, the periphery of this jaws part or this conical bore, and can cooperate with a middle hole of this cap, this flat surfaces of this circular protrusion inboard and this ring-shaped protrusion this flat surfaces of side especially flush, the inner circumferential surface of this centre hole of this lid cover is an inclined surface of similar rounding taper hole, and this inclined surface is smooth engaging each other with this flat surfaces of this circular protrusion part inboard of this gland main body upside.

52, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: this partly inboard flat surfaces of this circular protrusion is higher than the position at this ring-shaped protrusion this flat surfaces of side especially, and partly inboard this flat surfaces of this circular protrusion is the form on outstanding circular-arc surface.

53, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: the position is the pattern of similar circular-arc or taper inclined surface at the corner of the inner circumferential surface of this depressed part and roof intersection.

54, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 52 etc. out, it is characterized in that: the position is a pattern circular-arc or the taper inclined surface in the inner circumferential surface of this depressed part and the corner of roof intersection.

55, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, and it is characterized in that: this gland main body disposes an air displacement pipe, and this air displacement pipe extends vertically up to the inside of this gland main body.

56, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: this gland main body disposes a vertical perforation, one air displacement pipe is inserted in this vertical perforation, and the length of this air displacement pipe is less than the length of this vertical perforation, therefore with regard to its length, can have a residual quantity between the vertical perforation of this air displacement pipe with this, and an end of this air displacement pipe can with the upper surface flush of this gland main body, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body, the elastic force that clamp pressure produced, and the stress effect of pushing, can make that the elastomer of this air displacement pipe downside of position around this vertical perforation can be closed, and the pattern of similar lip, and can form one and confirm valve, leak outside to prevent liquid preparation or similar material.

57, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 55 etc. out, it is characterized in that: this gland main body disposes a hole, this hole has a bottom, the position is in the bottom of this hole, and this air displacement pipe can be inserted in this hole, this gland main body has an opening structure, this opening structure is selected from a kind of structure in the group that is made up of a cutting part and a duck eye, this opening structure vertically extends in the bottom of this hole, when the injection that is installed to a liquid preparation or similar object when this gland main body is extracted out and mouthful to be gone up, owing to be subjected to the clamp pressure that elastomer produced of this gland main body and the effect that stress is pushed, can make this opening structure produce a clamp pressure.

58, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 55 etc. out, it is characterized in that: this air displacement pipe comprises a tubular element, and this tubular element is filled with a water-repellent substance, and wherein this water-repellent substance is fair passes through wherein with air, and does not allow moisture to pass through.

59, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 58 etc. out, and it is characterized in that: this water-repellent substance can also intercept antibacterial.

60, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: this cutting port part that partly is tucked into this gland main body when a front end of a syringe or connecting elements, in the time of in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can flexibly be out of shape and open, when this front end of this syringe or connecting elements partly from this cutting port part of this gland main body, when extracting in this jaws part or this conical bore, this cutting port part of this gland main body, this jaws part or this conical bore can bounce back into original state and present the state of sealing.

61, mouth sealing device is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: a syringe or connecting elements have a ring-like anti-projection that pitches, this ring-like anti-projection position front end part that pitches at this syringe or connecting elements, so when this front end of this syringe or connecting elements partly is tucked in this cutting port part, this jaws part or this conical bore of this gland main body, this ring-like anti-projection that pitches can stop this front end part of this syringe or connecting elements, pitches to prevent this syringe or connecting elements.

62, a mouthful seal valve is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole or a plastics inner sleeve that embeds in this patchhole have a female thread groove, and have an external screw thread convex ridge on this front end part of this syringe or connecting elements, so this external screw thread convex ridge can be engaged in this female thread groove, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.

63, a mouthful seal valve is extracted in the injection of liquid preparation as claimed in claim 51 etc. out, it is characterized in that: this gland main body has a patchhole, this patchhole position is at the zone line of the upper surface of this gland main body, and a front end of a syringe or connecting elements partly can be inserted in this and inserts in the hole, this patchhole or a plastics inner sleeve that embeds in this patchhole have at least one first ring-type padlock partly, and this front end of this syringe or connecting elements partly has one second ring-type padlock partly, so this first ring-type padlock partly can partly engage mutually with this second ring-type padlock, make this syringe or connecting elements to link together, and can prevent that this syringe or connecting elements and this gland main body from getting loose with this gland main body.