CN1346662A - Exterior-applied ointment for treating skin injury accompanied with infection or durable ulcer and its preparing process - Google Patents
Exterior-applied ointment for treating skin injury accompanied with infection or durable ulcer and its preparing process Download PDFInfo
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- CN1346662A CN1346662A CN 01133296 CN01133296A CN1346662A CN 1346662 A CN1346662 A CN 1346662A CN 01133296 CN01133296 CN 01133296 CN 01133296 A CN01133296 A CN 01133296A CN 1346662 A CN1346662 A CN 1346662A
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- skin injury
- calomelas
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Abstract
An exterior-applied ointment for treating skin injury accompanied infection and intractable ulcer is prepared from 11 Chinese-medicinal materials including red sage root, rhubarb, rehmannia root, wolfberry bark, etc through proportional mixing, pre-processing and preparing ointment. Its advantages are short course of treatment, high curative effect, and no irritation to skin.
Description
The present invention relates to a kind of external used medicine that the skin injury companion infects, ulcer does not close up for a long time for the treatment of, is the externally-applied ointment of feedstock production with Chinese medicine specifically, the invention still further relates to the preparation method of this medicine.
Damage being meant that human body is subjected to disorganizations such as extraneous different caused by factors skin and flesh, muscles and bones, internal organs, generally speaking infective wound surface can have red, swollen, pain, skin ulcer face stale, have secretions simultaneously with generate heat, the with the passing of time performance such as disunion of weak, the open sore part.Heavy then threat to life.Whether skin or mucosa integrity according to the injury are damaged, and can be divided into closed injury and open injury.Open injury be meant the violence effect by sharp device, firearm or blunt make skin or mucosa damaged and have that wound is bled, deep tissue and external environment communication person.The damage exopathogen of therefore broken skin is easy to invade, and infects easily, so the deteriorated case multiterminal.
At present, modern medicine treatment skin open injury local debridement sterilization, the antibiotic etc of adopting are treated more, though symptom can be alleviated, the course of treatment is long, and wound healing is slow.What have is associated with local infection, or forms connective tissue proliferation.
The object of the present invention is to provide a kind of have poison holding removing the necrotic tissue, granulation promoting analgesic externally-applied ointment,, prevent bacteremia and septicemia to quicken the skin injury healing.
Another object of the present invention provides the preparation method of this externally-applied ointment.
Technical scheme of the present invention is based on motherland's medical science to the understanding of skin injury pathogenic factor and the characteristics of local treatment.Primary disease belongs to categories such as motherland's medical science " wound contamination ", " ulcer ", " skin infection ".The characteristics of its pathology are: stagnation of QI-blood, and evil outer the invading of poison, meridians block, and the meat corruption becomes pus.Therefore, discuss the principle of controlling according to differential diagnosis in tcm, achievement in conjunction with modern pharmacological research, clinical experience for many years, set forth one's views with poison holding removing the necrotic tissue, granulation promoting pain relieving, with Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, the Radix Rehmanniae, Cortex Lycii, make and Semen Strychni, pure Chinese medicines such as grass, Corium elephatis, Calomelas, Oleum Sesami, Cera Flava, Radix Glycyrrhizae are developed into the damage necrosis removing and granulation promoting plaster herein, treatment skin injury companion infects or ulcer disunion of a specified duration short treating period, evident in efficacy.
1, medicine of the present invention is made by following component: (consumption is a weight portion)
Radix Salviae Miltiorrhizae 10-20 part Radix Angelicae Dahuricae 5-10 part Cortex Lycii 6-15 part Radix Et Rhizoma Rhei 9-15 part
Radix Rehmanniae 10-15 part Semen Strychni (processed) 3-10 part Radix Arnebiae (Radix Lithospermi) 3-15 part Corium elephatis 7-15 part
Calomelas 0.1-0.3 part Radix Glycyrrhizae 6-12 part Radix Angelicae Sinensis 9-20 part
2, the formula optimization weight proportion scope of preparation medicine of the present invention:
Radix Salviae Miltiorrhizae 10-15 part Radix Angelicae Dahuricae 6-10 part Cortex Lycii 6-10 part Radix Et Rhizoma Rhei 10-15 part
Radix Rehmanniae 10-15 part Semen Strychni (processed) 3-6 part Radix Arnebiae (Radix Lithospermi) 3-9 part Corium elephatis 8-12 part
Calomelas 0.1-0.25 part Radix Glycyrrhizae 6-10 part Radix Angelicae Sinensis 9-15 part
3, the optimum weight proportioning of medicine of the present invention is:
10 parts of 6.7 parts of Radix Et Rhizoma Rhei of 6.1 parts of Cortex Lycii of 10 parts of Radixs Angelicae Dahuricae of Radix Salviae Miltiorrhizae
8 parts of 3.3 parts of Corium elephatiss of 3.3 portions of Radix Arnebiae (Radix Lithospermi)s of 11 parts of Semen Strychni (processed)s of the Radix Rehmanniae
10 parts of 6.5 parts of Radix Angelicae Sinensis of 0.1 portion of Radix Glycyrrhizae of Calomelas
Above-mentioned each component is made medicine production method of the present invention:
1, selected in proportion above-mentioned raw materials;
2, choose Radix Arnebiae (Radix Lithospermi) and steeped 24 hours with Oleum Sesami, all the other raw materials (except that Calomelas) steeped 2 hours with Oleum Sesami;
3, above-mentioned raw material with the Oleum Sesami stain is fried withered with Oleum Sesami, filtration adding Cera Flava stirs molten, and the cooling back adds the Calomelas stirring, and natural laking had both got the uniform and smooth ointment.
Clinical drug of the present invention uses the result to show:
1, to select Chinese medicine for use be raw material in the present invention, and each component meets the pharmacopeia regulation.Utilize the comprehensive function treatment injury of the Chinese medicine of respectively distinguishing the flavor of, nontoxic, harmless to human body, have no side effect.
2, the present invention must not decoct, and is easy to use.
3, no matter weight all can use separately disease.
Infect or the therapeutic effect of ulcer disunion of a specified duration for showing that medicine of the present invention is mixed skin injury, the present invention observes through the clinical effect of 306 routine systems.Male's 220 examples, women's 86 examples, oldest 65 years old, minimum 15 years old.The wound classification: incision 103 examples, crush injury 71 examples, twisting tied wound 51 examples, avulsion 46 examples, 35 examples are hindered in friction; Wound area maximum 4 * 5cm, minimum 1.5 * 2cm; The darkest 0.6cm, minimum 0.2cm.Neat N/D 87 examples of wound, damaged 219 examples of wound; Fresh wound 179 examples, infected wound 58 examples, old is hindered 69 examples of non-healing wounds; The shortest 3 hours of the course of disease, the longest 20 days.
Test statistics shows: in 306 examples of treatment, and maximum 16 times of medication, minimum average 6 times, total effective rate 98.6%.
Embodiment:
Take by weighing raw material (kilogram) by following proportioning:
Radix Salviae Miltiorrhizae 1000 Radixs Angelicae Dahuricae 300 Cortex Lycii 335 Radix Et Rhizoma Rhei 500
The Radix Rehmanniae 510 Semen Strychni (processed)s 165 Radix Arnebiae (Radix Lithospermi)s 165 Corium elephatiss 300
Calomelas 50 Radix Glycyrrhizaes 335 Radix Angelicae Sinensis 500
Its preparation method is as follows:
Choose above-mentioned raw materials in proportion, choosing Radix Arnebiae (Radix Lithospermi) earlier steeped 24 hours with Oleum Sesami, except that Calomelas, all the other raw materials steeped 2 hours with Oleum Sesami, again that above-mentioned raw material with Oleum Sesami stain is fried withered with Oleum Sesami, and filter and add Cera Flava and stir moltenly, add Calomelas after cooling again and evenly stir, the nature laking had both got the uniform and smooth ointment.
Claims (6)
1, a kind ofly treat the externally-applied ointment that skin injury companion infects or ulcer does not close up for a long time, it is characterized in that it is the unguentum of being made by the following weight proportion raw material:
Radix Salviae Miltiorrhizae 10-20 part Radix Angelicae Dahuricae 5-10 part Cortex Lycii 6-15 part Radix Et Rhizoma Rhei 9-15 part
Radix Rehmanniae 10-15 part Semen Strychni (processed) 3-10 part Radix Arnebiae (Radix Lithospermi) 3-15 part Corium elephatis 7-15 part
Calomelas 0.1-0.3 part Radix Glycyrrhizae 6-12 part Radix Angelicae Sinensis 9-20 part
2, the externally-applied ointment that treatment skin injury companion according to claim 1 infects or ulcer does not close up for a long time, wherein the weight proportion of each raw material is:
Radix Salviae Miltiorrhizae 10-15 part Radix Angelicae Dahuricae 6-10 part Cortex Lycii 6-10 part Radix Et Rhizoma Rhei 10-15 part
Radix Rehmanniae 10-15 part Semen Strychni (processed) 3-6 part Radix Arnebiae (Radix Lithospermi) 3-9 part Corium elephatis 8-12 part
Calomelas 0.1-0.25 part Radix Glycyrrhizae 6-10 part Radix Angelicae Sinensis 9-15 part
3, the externally-applied ointment that treatment skin injury companion according to claim 1 infects or ulcer does not close up for a long time, wherein the weight proportion of each raw material is:
10 parts of 6.7 parts of Radix Et Rhizoma Rhei of 6.1 parts of Cortex Lycii of 10 parts of Radixs Angelicae Dahuricae of Radix Salviae Miltiorrhizae
8 parts of 3.3 parts of Corium elephatiss of 3.3 portions of Radix Arnebiae (Radix Lithospermi)s of 11 parts of Semen Strychni (processed)s of the Radix Rehmanniae
10 parts of 6.5 parts of Radix Angelicae Sinensis of 0.1 portion of Radix Glycyrrhizae of Calomelas
4, according to claim 1,2 or 3 externally-applied ointments that described treatment skin injury companion infects or ulcer does not close up for a long time, it is characterized in that described medicament is a said dosage form on any pharmaceutics.
5, the externally-applied ointment that treatment skin injury companion according to claim 4 infects or ulcer does not close up for a long time is characterized in that said medicament is an ointment.
6, a kind of preparation method that is used for above-mentioned medicine, selected in proportion above-mentioned raw materials removes Calomelas external Oleum Sesami stain with medicine, and reuse Oleum Sesami is fried withered, and filtration adding Cera Flava stirs molten, and the cooling back adds the Calomelas stirring, and natural laking had both got the uniform and smooth ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133296 CN1346662A (en) | 2001-09-20 | 2001-09-20 | Exterior-applied ointment for treating skin injury accompanied with infection or durable ulcer and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01133296 CN1346662A (en) | 2001-09-20 | 2001-09-20 | Exterior-applied ointment for treating skin injury accompanied with infection or durable ulcer and its preparing process |
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| CN1346662A true CN1346662A (en) | 2002-05-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 01133296 Pending CN1346662A (en) | 2001-09-20 | 2001-09-20 | Exterior-applied ointment for treating skin injury accompanied with infection or durable ulcer and its preparing process |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100411667C (en) * | 2004-03-10 | 2008-08-20 | 张土荣 | Immune balancing energy restoring ointment and its manufacturing method |
| CN101361890B (en) * | 2008-09-28 | 2011-07-27 | 中国人民解放军第四军医大学 | Traditional Chinese medicine formulation for treating radioactivity skin impairment |
| CN105796744A (en) * | 2016-03-29 | 2016-07-27 | 李绍斌 | Toxin-removal traditional Chinese medicine ointment |
| CN108926704A (en) * | 2018-08-06 | 2018-12-04 | 纪永利 | A kind of skin wounds and ulcers wound is removed necrosis and promoted granulation the preparation method of spray |
| CN111617162A (en) * | 2020-06-08 | 2020-09-04 | 上海交通大学医学院附属第九人民医院 | Wound repair ointment and preparation method and application thereof |
-
2001
- 2001-09-20 CN CN 01133296 patent/CN1346662A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100411667C (en) * | 2004-03-10 | 2008-08-20 | 张土荣 | Immune balancing energy restoring ointment and its manufacturing method |
| CN101361890B (en) * | 2008-09-28 | 2011-07-27 | 中国人民解放军第四军医大学 | Traditional Chinese medicine formulation for treating radioactivity skin impairment |
| CN105796744A (en) * | 2016-03-29 | 2016-07-27 | 李绍斌 | Toxin-removal traditional Chinese medicine ointment |
| CN108926704A (en) * | 2018-08-06 | 2018-12-04 | 纪永利 | A kind of skin wounds and ulcers wound is removed necrosis and promoted granulation the preparation method of spray |
| CN111617162A (en) * | 2020-06-08 | 2020-09-04 | 上海交通大学医学院附属第九人民医院 | Wound repair ointment and preparation method and application thereof |
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