CN1295872A - Microwave radiation cancer-curing apparatus and its acupuncture application - Google Patents

Abstract

The present invention discloses a microwave radiation equipment for curing cancer. It adopts waveguide needle array adjustable radiation head and its combined equipment integrating computer regulation, control, temp. measurement and image into one whole. The radiation head includes a hollow needle whose interior contains a central signal needle, and a grounding needle fixed on the circular stable-fixer; the hollow needle and grounding needle are grounded at the same time, the exterior of grounding needle is sheathed with metallic mosh flexible horn; in addition, a hand-held arm, an oscillation length regulator and a coaxial antenna intra-body depth regulator which are coaxially mounted with hollow needle. For human body and living body, it can make microwave radiation and acupuncture therapy in non-insurting, inserting and semi-inserting modes and their mixed mode. It also has the advantage of microwave radiation heat therapeutic equipment.

Description

Microwave radiation cancer-curing apparatus and acupuncture-moxibustion purposes

The present invention relates to medical instruments field, particularly microwave medical apparatus and instruments and microwave acupuncture application field.

Cancer is one of principal disease that threatens the human life, the traditional method of treatment cancer has: adopt the surgical resection cancerous issue, X-radiation treatment or chemotherapy cancerous issue, above-mentioned traditional method remains the main treatment means of present treatment cancer.But the limitation of these traditional therapies is fairly obvious, and any Therapeutic Method all can not effectively be treated the cancer of various cancers and partes corporis humani position simultaneously.X-radiation treatment and chemotherapy also have serious adverse, as: reduce the quantity of human white blood ball, the damage people's is healthy.

Facts have proved microwave heat therapeutic method and other therapies such as physics, the collaborative use of chemotherapy, treatment of cancer is shown outstanding especially curative effect.Modern medicine has proved that most of human cancer cells can be dead when heating to 42 ℃ to 45 ℃, and its reason is that cancer cell has for normal cell that its heat resist power is poor, capacity of heat transmission difference and easy characteristics such as elevated temperature; Therefore cancerous lesion is organized and just is very suitable for by the microwave radiation thermotherapy.In the time of in microwave incides the tissue that resembles the high like this water capacity of cancer cell, high dielectric radio, the characteristics that the cancerous lesion tissue temperature raises and is exceedingly fast and has the selectivity intensification.Use well-designed microwave irradiation therapy device to concentrate the position that focuses on required heating to microwave energy.Therefore, cancer cell adds that to the stronger sensitivity of temperature the focus characteristics of microwave radiation device makes the microwave radiation heat treatment therapeutic device be improved to the selectivity of cancer cell, but the selectivity kill cancer cell of higher degree and do not damage human normal tissue.

In general should possess following characteristics to the effective microwave hyperthermia device of treatment cancer: 1, microwave radiation penetration cell tissue depth is enough so that the cancerous issue than the position, deep can effectively be heated, and the while is the injuring normal cell tissue not; 2, comparatively ideal Temperature Distribution is arranged, promptly temperature is enough high and evenly in the cancerous lesion tissue, outside the cancerous lesion tissue and the interior temperature of peripheral cell tissue enough low; 3, the energy deposition figure in the pathological tissues should be adjustable, and fine-tuning, so that the cancerous lesion tissue of thermotherapy different parts, different depth, and the in-house high temperature hotspot of metastasis; 4, energy better dynamic balance between heating uniformity and selectivity; 5, the temperature of cancerous lesion tissue and patient's psychophysical characteristics can obtain at-once monitor, feedback in the thermotherapy process, so that the thermotherapy process is controlled effectively.

In the past about ten years in, the technical scheme of various microwave hyperthermia devices has been proposed, non-insertion type of the employing that they have or the employing insertion type that has, the cancerous lesion tissues of the different sizes that are suitable for different lengths of penetration such as shallow table or deep that have.Make a general survey of existing microwave hyperthermia device, they all fail to satisfy simultaneously These characteristics.Traditional non-insertion type heat treatment therapeutic device adopts phase place and spoke degree control array, is suitable for heating deep large volume interstitial laser photocoagulation; But length of penetration is not enough, is easy to produce quiet ripple focus, can't realize really that the control of energy focusing and focus moves.The less cancerous issue with regard to being unfavorable for treating modal clinically deep like this.On the other hand, existing insertion type heat treatment therapeutic device only adopts single radiation head usually, so just shortage focusing or heating efficiency equably.Existing insertion type device also can't be determined Temperature Distribution border preferably simultaneously, thereby reaches real selectivity heating.Generally speaking, existing microwave hyperthermia device technical scheme is unusual imperfection also, does not also occur a kind ofly collecting non-insertion type and insertion type is the heat treatment therapeutic device of one, to be fit to the cancerous issue heating to different parts and different depth.

The objective of the invention is to invent a kind of microwave irradiation therapy equipment existing microwave radiation heat treatment unit advantage and that overcome the prior art shortcoming that has simultaneously.

Another object of the present invention is to utilize microwave to strengthen the stimulation of acupuncture to human body, and the shortening acupuncture is to the action time of human body.

Microwave cancer-curing apparatus provided by the present invention is applied widely, applicable to most cancerous protuberances of human body and organism, and does not have traditional surgery and physical chemistry to control the side effect of cancer method.

Technical scheme of the present invention is achieved in that the present invention has adopted a kind of microwave heating novel system first; This system had both improved the uniformity of local heating in cancerous issue, had taken into account the heat selective that adds from universe again.The array that this novel apparatus system is made up of a radiation head or many radiation heads connects microwave source, and computer control, thermometric and three-dimensional image system form.It can be widely used in microwave heat therapeutic, microwave acupuncture, both can adopt non-insertion type, can adopt the mixing of insertion type, half insertion type or three kinds of modes again.

The innovation part that above-mentioned used radiation head is this invention, it is by constituting around an array grounding pin surrounds heated object around the center signal pin.It is darker that such structure is convenient to make microwave propagation to get, and reduces echo, and improved the sharpness of border degree that hot temperature distributes greatly.Such structure even make single active antenna that focusing power just be arranged.The roughly the same axis antenna of core can be adjusted its position that enters human body and radiation oscillation length neatly, so that make just the change ability of heat deposition distribution of single radiation head, add frequency, the phase place of each radiation head, the computer regulating of spoke degree, can realize the purpose of optimization thermotherapy fully.The aerial array that can form multiple various combination is to be fit to the thermotherapy of the different size tumor of different piece.So just constituted collection insertion type and non-insertion type, the collection microwave is controlled cancer and the microwave acupuncture-moxibustion are one, is applicable to that diverse location, different depth and different big or small cancerous lesion organize the microwave hyperthermia device multi-functional, adjustable, that motility is strong.

The present invention adopts melt computer regulating, thermometric and the image of the adjustable radiation head of guided wave pin array and composition thereof to be the device of one first, human body or organism is carried out the microwave radiation thermotherapy and the acupuncture treatment of non-insertion type or insertion type.

In these systems, radiation head is most important parts, and it is various informative, as bipolar rod, needle-like, two flat board, waveguide head, loudspeaker, flat plane antenna etc.The system that the antenna of different structure is formed is owing to the differ thermotherapy of the cancerous lesion tissue that is applicable to human body and organism different depth and different parts of its permeability.

The present invention is described in further detail below in conjunction with accompanying drawing and preferred forms:

Fig. 1 microwave radiation cancer-curing and microwave acupuncture-moxibustion device constitute sketch map;

The structure of Fig. 2 active antenna and microwave field distribution schematic diagram;

The complete insertion type scheme of Fig. 3 is applicable to that deep cancerous lesion organizes the thermotherapy sketch map;

Fig. 4 half insertion type scheme is applicable to that the cancerous lesion of moderate depth organizes the thermotherapy sketch map;

The non-insertion type scheme of Fig. 5 is applicable to the thermotherapy sketch map of epidermis or superficial part cancerous lesion tissue.

Shown in Figure 1, be the microwave radiation cancer-curing of this invention and the formation sketch map of microwave needle moxibustion device 1.One or an array radiation head 3 are to cancerous issue 18 microwave radiation energies in the patient body 21.Cancer and microwave needle moxibustion device 1 are controlled in the 2 controlled microwave radiation of computer central control board, and with each radiation head 3 interconnecting interface.Computer central control board 2 provides a kind of interactive mode, and user can be imported data such as instruction or frequency, phase place, spoke degree here and come controlled microwave source 13 respectively, amplifirer 15, and phase shift meter 16 etc.Computer central control board 2 also can obtain Temperature Distribution and the total information such as physiological reflex of patient in the cancerous issue 18, specifically realize, and show cancerous issue 18 and the position of inserting radiation head 3 by three-dimensional image display system 24 by temperature and physiological monitoring system 23.The information that computer central control board 2 obtains is returned feedback and is gone to regulate automatically the parameter of microwave radiation cancer-curing and microwave needle moxibustion device 1 to reach the purpose of optimizing thermotherapy.When cancerous issue 18 temperature are too high when surpassing 45 ℃, computer central control board 2 can reduce the power of each radiation head 3 automatically, otherwise, will increase radiant power.When high temperature dot departed from cancerous issue 18 in the Temperature Distribution in patient body's 21 bodies, computer central control board 2 can by the required frequency of automatic adjusting and phase place be adjusted or realize the change that the heat temperature distributes by manually or automatically regulating the position and the degree of depth of respectively inserting pin.

In temperature and physiological monitoring system 23, the series of temperature pick off adheres to or is independent of on the radiation head 3, carries out real time temperature and measures.For not by microwave interference, preferably select commercially available temperature-sensitive or photosensitive temperature sensor.Its physiology monitoring can comprise data such as blood pressure, heart rate, body temperature.

Three-dimensional image display system 24 is as helping pin in patient body 21.Preferably adopt and can buy the NMR imaging (NMR) that obtains, or computed tomography systems such as (CT), disturb to avoid microwave radiation.

Microwave source 13 can adopt the solid-state circuit type of commercially available or homemade technology maturation, or vacuum tube type.Because the needs of different parts and different depth heating, microwave signal will be used the selection of broad frequency band, and from 50MHZ to 3000MHZ, power is from tens watts to hundreds of watts magnitude.Its operating frequency depends on the size of institute's length of penetration and cancerous issue 18.Significantly, best reference temperature(TR) of the selection of above-mentioned all parameters and physiological monitoring system 23 return the real-time hot temperature measurement signal of presenting back.

Microwave source 13 links with power splitter 14, is divided into several roads signal, connects amplifirer 15, phase shift meter 16 more respectively.These devices all with computer central control board 2 interfaces so that realize control automatically.Link by microwave cable line 17 and one or several radiation heads 3 at last.In these microwave device configurations, note reaching 50 ohm impedance matching.

As shown in Figure 2, radiation head 3 is made of around several grounding pins 6 a center signal pin 5, so that will need the cancerous issue 18 of thermotherapy to surround.These pins are all made by the good conductor metal, center signal pin 5 constitutes coaxial antenna with hollow needle 4, hollow needle 4 is wanted common ground with grounding pin 6, and center signal pin 5 can be free to slide along axis front and back, and the degree of depth of center signal pin 5 insertion human bodies and the length of exposure can be regulated by external actuator.During concrete operations, hold hand-held arm 10 and will insert human body surface together by the coaxial antenna that center signal pin 5 and hollow needle 4 are formed below 22, concussion length adjuster 11 is used to regulate the length of exposure of center signal pin 5, and coaxial antenna is gone into the insertion depth that body depth adjuster 12 is regulated whole coaxial antenna.Because radiation head 3 has a little microwave leakage with the contact position of human body surface 22, therefore adopt metal net shaped software loudspeaker 8 to shield leakage, and fill deionized-distilled water bag 7 within it improving the impedance matching between active antenna and the human body, and has the advantage that reduces human body surface 22 temperature.When especially adopting non-insertion type to treat, metal net shaped software loudspeaker 8 and deionized-distilled water bag 7 are just indispensable.So just constituted complete radiating element, the microwave field 19 that is produced is bundled in the cancerous issue 18 preferably, and forming perfectly, microwave field 19 distributes.Such microwave field 19 will make the cells in vivo polar molecule shake, and with molecular friction on every side, and heat effect take place; On the other hand, intravital charged free son produces electric current under the effect of microwave field 19, thereby causes an ohm heat effect.Thereby in cancerous issue 18, just produced localized hyperthermia, thereby reach the purpose of thermotherapy.User can be regulated radiation direction Figure 20 of antenna easily, neatly, thereby makes heat deposition figure adjustable variableization.

The important novel point of another of this system is: many grounding pins 6 can be closely around surrounding by the cancerous issue 18 of thermotherapy, and these grounding pins 6 link together by the firm device 9 of annular, and are fixed on the metal net shaped software loudspeaker 8.Microwave is bundled in the cancerous issue 18, thereby has significantly reduced damage, therefore improved selectivity, or strengthened focusing power normal surrounding tissue.And these pins also can change its insertion depth, realize needed radiation profiles to regulate.

This flexibly adjustable radiation head 3 is easy to realize that a heat treatment therapeutic device just can treat the cancerous issue 18 of different parts different depth and different sizes.With human body surface 22 is reference, both can realize full insertion type shown in Figure 3, is suitable for deep but the thermotherapy of less cancerous issue 18; Can realize half insertion type shown in Figure 4 again, promptly only center signal pin 5 is inserted, and is suitable for cancerous issue 18 thermotherapies of moderate depth; Also can realize non-insertion type heating shown in Figure 5, be applicable to the thermotherapy of shallow table cancerous issue 18.These different implantation modes have produced different radiation direction Figure 20, so that the cancerous issue 18 of the different sizes of treatment different depth.As required, these radiation heads 3 can at random be organized battle array.Thisly finish unitized thermal therapy system and scheme is an another important feature of the present invention.

Tailored radiation head 3 in the above-described system can be directly used in the microwave acupuncture-moxibustion.Here, the acupuncture point has become target rather than above-mentioned cancerous cell.Higher frequency and lower power will be used, because the target of this moment is less.Similarly, its insertion type and non-insertion type scheme all can be employed.The significant advantage of microwave acupuncture-moxibustion is that acupuncture point or neurokyme obtain stimulation more quickly and effectively.Its non-insertion type microwave acupuncture-moxibustion do not bring patient's misery, have more advantage.This has embodied the multifunction of the device of this invention again.

More than described the optimum working mode of this system, but be not limitation of the invention.Various modifications of the present invention all are considered as category of the present invention.

Claims (6)

1. new type of microwave radiation cancer-curing apparatus, linked to each other with microwave source (13), single or multiple power splitter (14), single or multiple amplifirer (15), single or multiple phase shift meter (16), single or multiple radiation head (3) in regular turn by microwave cable line (17) by computer central control board (2), temperature and physiological monitoring system (23), three-dimensional image display systems (24) are formed.

2. microwave radiation cancer-curing apparatus as claimed in claim 1, used radiation head (3) includes center signal pin (5) around one group of grounding pin (6) that is fixed on the firm device (9) of annular by hollow needle (4), hollow needle (4) and grounding pin (6) be ground connection simultaneously, grounding pin (6) is outer to be surrounded by metal net shaped software loudspeaker (8), adds with hand-held arm (10), concussion length adjuster (11) and the coaxial antenna of hollow needle (4) on same axis and goes into body depth adjuster (12) formation.

3. microwave radiation cancer-curing apparatus as claimed in claim 1, the arrangement mode of its radiation head (3) can be complete annular array, part annular array and cubical array.

4. microwave radiation cancer-curing apparatus as claimed in claim 1, its radiation head (3) can be the mixing of insertion type, non-insertion type, half insertion type and three kinds of modes.

5. microwave radiation cancer-curing apparatus as claimed in claim 2, the center signal pin (5) of its radiation head (3) can be free to slide along co-axial hollow needle (4) axis, and the degree of depth of hollow needle (4) insertion human body and the length that center signal pin (5) exposes hollow needle (4) are gone into body depth adjuster (12) and concussion length adjuster (11) adjusting by coaxial antenna.

6. microwave radiation cancer-curing apparatus as claimed in claim 1, its radiation head (3) can directly be applied to human acupoint with insertion type or non-insertion type, utilizes microwave energy replacement acupuncture acupuncture needle to reach the purposes of the treatment disease that excites nerve.

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