CN1256930A - Medicine for preventing and controlling tumor and health-care food - Google Patents
Medicine for preventing and controlling tumor and health-care food Download PDFInfo
- Publication number
- CN1256930A CN1256930A CN98122092A CN98122092A CN1256930A CN 1256930 A CN1256930 A CN 1256930A CN 98122092 A CN98122092 A CN 98122092A CN 98122092 A CN98122092 A CN 98122092A CN 1256930 A CN1256930 A CN 1256930A
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- China
- Prior art keywords
- tumor
- garcinia mangostana
- medicine
- health
- care food
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- Pending
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 41
- 239000003814 drug Substances 0.000 title claims abstract description 16
- 235000013305 food Nutrition 0.000 title abstract description 6
- 229940079593 drug Drugs 0.000 title description 2
- 240000006053 Garcinia mangostana Species 0.000 claims abstract description 32
- 235000017048 Garcinia mangostana Nutrition 0.000 claims abstract description 32
- 238000002360 preparation method Methods 0.000 claims abstract description 13
- 235000013402 health food Nutrition 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 8
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 5
- 239000002002 slurry Substances 0.000 claims description 4
- 241000700605 Viruses Species 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002994 raw material Substances 0.000 abstract description 5
- 239000002775 capsule Substances 0.000 abstract description 2
- 239000012263 liquid product Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 238000004804 winding Methods 0.000 description 6
- 241000699660 Mus musculus Species 0.000 description 5
- 238000011580 nude mouse model Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 239000002671 adjuvant Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 3
- 208000005718 Stomach Neoplasms Diseases 0.000 description 3
- 206010017758 gastric cancer Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 201000011549 stomach cancer Diseases 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 235000016998 Ribes burejense Nutrition 0.000 description 2
- 241000735566 Ribes burejense Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 108010016626 Dipeptides Proteins 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 230000009246 food effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000012771 pancakes Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a medicine and health-care food for curing and preventing tumor. It is characterized by that 10-100% garcinia mangostana preparation is used as raw material, and auxiliary material is added according to the traditional preparation process and makes them into the medicine or health-care food with the function of curing and preventing tumor. Said invention can be made into tablet, capsule and liquid product.
Description
The present invention relates to medical domain and field of health care food, especially a kind of medicine and health food with anti-curing oncoma.
Cancer is to influence first of the four big diseases of human health, Therapeutic Method is nothing more than being excision, amic therapy method and X-ray therapy at present, though these Therapeutic Method all have certain curative effect, and advantage is arranged respectively, all exist to the patient and bring many side effect and misery.Therefore people are seeking more effective, side effect new treatment or medicine still less always.The present invention relates to how to prevent curing oncoma, utilize aspects such as health food effect to do a large amount of research and repaid examination.
Purpose of the present invention, the health food that just is to provide a kind of medicine of the anti-curing oncoma that has no side effect and has the control tumor function.
Technical scheme of the present invention is, inherited and carried forward the thought that Chinese medicine is learned, and quotes that not have few less virus garcinia mangostana be raw material, is made into medicine or various other health food.
Garcinia mangostana is that a kind of original Peru and Chile are northern, an and Colombian kind of plant, people eat it as a kind of fruit for a long time, because the environmental condition requirement that its growth is required, China is introduction of plant once, but, expansion production, output, quality all are affected because of plant susceptible virus.The applicant has carried out many-sided research to performance of garcinia mangostana and cultivation and the cultivation technique aspect of seedling, and done a large amount of experiments, experimental results show that garcinia mangostana fruit and stem and leaf except that containing a certain amount of sugar, protein and little fat, it also contains higher amount vitamin C, calcium, potassium, ferrum, zinc and selenium and molybdenum element, and is rich in bioactive substances such as multiple alkaloid, sugared polysaccharide.Because these have prevention effect well to tumor, simultaneously pancake blood fat, blood pressure lowering and blood sugar lowering are all had tangible effect.Therefore the present invention is primary raw material with the garcinia mangostana, it is that garcinia mangostana powder, garcinia mangostana juice, garcinia mangostana slurry etc. are primary raw material that garcinia mangostana is made the garcinia mangostana preparation with common traditional processing mode, increase the adjuvant that some traditional pharmacy and health food manufacturing process need again, make and contain medicine or the health food that garcinia mangostana is 10%-90%.Because the Feng Shicheng of garcinia mangostana, making by its garcinia mangostana is main medicine or health food tool
The invention process row three are capsule
1, garcinia mangostana powder: 30.12%
2, compound enzyme: 10.84%
3, starch: 37.34%
4, Ribes burejense powder: 21.68%
The above-mentioned raw materials mixing is according to dosage incapsulated.
Product of the present invention has the effect of good antitumor, and this inventor has been done a large amount of experiments.
The laboratory animal that the present invention adopts is the nude mice of inoculated tumour: nude mice is BZLB/C, and 4 phases of feeding weigh about 15 grams, inoculate oncocyte fragment 0.2ml then respectively, connects after the tumor 5 days and begins measurement volumes everyday, and last kill animals is taken out the tumor piece, and the weighing tumor is heavy.Struma is respectively: hepatocarcinoma; Gastric cancer SGC, pulmonary carcinoma LAX.Experimental animal is divided into two groups, and test group is fed the replacement drinking water of product of the present invention, control group fed distilled water when the inoculation beginning.
The result of the test example:
1, gastric cancer SGC
After the test winding tumor the 5th day, the tumor average external volume was-0.394cm
Connect Ahau after the tumor, tumor average external volume 0.526cm weighs 0.34 gram.
After the contrast winding tumor the 5th day, the tumor average external volume was 0.338cm
Connect after the tumor second day, tumor average external volume 5.106cm, tumor weighs 4.82 grams.
As seen: feed " garcinia mangostana preparation " reaches 92.95% to the signature ratio of outflow of nude mice gastric cancer.
2, hepatocarcinoma QGY
Feed by " garcinia mangostana preparation "
After the test winding tumor the 5th day, the tumor average external volume was 0.412cm
Connect after the tumor the 29 day, tumor average external volume 5.06cm tumor weighs 3.8 grams.
After the contrast winding tumor the 5th day, the tumor average external volume was 0.498cm
Connect after the tumor the 29 day, tumor average external volume 10.61cm tumor weighs 7.16 grams.
As seen: feed " garcinia mangostana preparation " reaches 51.2% to the kind ratio of outflow of nude mice hepatocarcinoma.
3, pulmonary carcinoma LAX
After the test winding tumor the 5th day, the tumor average external volume was 0.272cm
Connect Ahau after the tumor, tumor average external volume 3.076cm tumor weighs 3.15 grams.
After the contrast winding tumor the 5th day, the tumor average external volume was 0.298cm
Connect Ahau after the tumor, tumor average external volume 7.20cm, tumor weighs 6.18 grams.
As seen: feed " garcinia mangostana preparation " reaches 49.3% effect that treatment or anti-curing oncoma arranged to the tumor rate of nude mice pulmonary carcinoma.
Its prescription of pharmacy of the present invention can be:
1, garcinia mangostana preparation: 10%-100%
2, traditional drugs goods adjuvant: 100-10%
Wherein the garcinia mangostana preparation can be garcinia mangostana powder, garcinia mangostana juice, garcinia mangostana slurry, and traditional medicine goods adjuvant is forming agent, distilled water etc.
The prescription of making health food can be
1, garcinia mangostana preparation: 10-100%
2, food additive: 100-10%
Wherein the garcinia mangostana preparation is the juice of the powder made by garcinia mangostana natural juice, extraction, slurry etc.It is adjuvant that the additive of food adds the additive of being determined by Traditional health care food manufacturing prescription according to different situations such as the type of making health food such as liquid, solids.
Example of the present invention one is for to make tablet medicine with product:
1, garcinia mangostana preparation powder 30.12%
2, compound enzyme 10.84%
3, starch 18.07%
4、VC 3.6％
5, dextrin 12%
6, citric acid 2.4%
7, dipeptides sugar 1.2%
8, Ribes burejense powder 21.7%
Above-mentioned prescription is made tablet by traditional processing mode
Example two of the present invention is an oral liquid
1, garcinia mangostana liquid: 60.9%
2, Sucus Rosae Normalis: 24.39%
3, Icing Sugar: 4.9%
4, citric acid: 4.9%
Above percentage ratio is dissolved in the 25L de-ionate
5, excess water: 25L
By traditional oral liquid processing technique, processing back rolling bottle gets final product.
Claims (2)
1, a kind of medicine of anti-curing oncoma and health food is characterized in that, wherein the garcinia mangostana formulation content is at 10-100%.
2, control tumour medicine according to claim 1 and health food is characterized in that the garcinia mangostana preparation is by the powder, juice, the slurry that do not have or the less virus garcinia mangostana is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98122092A CN1256930A (en) | 1998-12-14 | 1998-12-14 | Medicine for preventing and controlling tumor and health-care food |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98122092A CN1256930A (en) | 1998-12-14 | 1998-12-14 | Medicine for preventing and controlling tumor and health-care food |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1256930A true CN1256930A (en) | 2000-06-21 |
Family
ID=5227573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98122092A Pending CN1256930A (en) | 1998-12-14 | 1998-12-14 | Medicine for preventing and controlling tumor and health-care food |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1256930A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1562619A4 (en) * | 2002-10-30 | 2008-10-29 | Dbc Llc | Nutraceutical mangosteen composition |
| US9629991B1 (en) | 2016-06-08 | 2017-04-25 | Eclipse Aesthetics, LLC | Disposable radio frequency needle cartridges having absorbing containment barriers |
| US9636491B1 (en) | 2016-06-08 | 2017-05-02 | Eclipse Aesthetics, LLC | Disposable needle cartridges having absorbing contaminant barriers |
-
1998
- 1998-12-14 CN CN98122092A patent/CN1256930A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1562619A4 (en) * | 2002-10-30 | 2008-10-29 | Dbc Llc | Nutraceutical mangosteen composition |
| US9629991B1 (en) | 2016-06-08 | 2017-04-25 | Eclipse Aesthetics, LLC | Disposable radio frequency needle cartridges having absorbing containment barriers |
| US9636491B1 (en) | 2016-06-08 | 2017-05-02 | Eclipse Aesthetics, LLC | Disposable needle cartridges having absorbing contaminant barriers |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |