CN1244131A - 包含两种充气微泡的造影剂 - Google Patents
包含两种充气微泡的造影剂 Download PDFInfo
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- CN1244131A CN1244131A CN 98801948 CN98801948A CN1244131A CN 1244131 A CN1244131 A CN 1244131A CN 98801948 CN98801948 CN 98801948 CN 98801948 A CN98801948 A CN 98801948A CN 1244131 A CN1244131 A CN 1244131A
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- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000001433 sodium tartrate Substances 0.000 description 1
- 229960002167 sodium tartrate Drugs 0.000 description 1
- 235000011004 sodium tartrates Nutrition 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 229940083466 soybean lecithin Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 125000003696 stearoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000008227 sterile water for injection Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- IAQRGUVFOMOMEM-ONEGZZNKSA-N trans-but-2-ene Chemical compound C\C=C\C IAQRGUVFOMOMEM-ONEGZZNKSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- OCEBOBGSOQRMQZ-UHFFFAOYSA-N trifluoromethylcyclopentane Chemical compound FC(F)(F)C1CCCC1 OCEBOBGSOQRMQZ-UHFFFAOYSA-N 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9701237.1 | 1997-01-22 | ||
| GBGB9701237.1A GB9701237D0 (en) | 1997-01-22 | 1997-01-22 | Improvements in or relating to contrast agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1244131A true CN1244131A (zh) | 2000-02-09 |
Family
ID=10806374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98801948 Pending CN1244131A (zh) | 1997-01-22 | 1998-01-22 | 包含两种充气微泡的造影剂 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0966305A1 (no) |
| JP (1) | JP2001508454A (no) |
| CN (1) | CN1244131A (no) |
| AU (1) | AU5674098A (no) |
| CA (1) | CA2278750A1 (no) |
| GB (1) | GB9701237D0 (no) |
| NO (1) | NO993438D0 (no) |
| WO (1) | WO1998032468A1 (no) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109529033A (zh) * | 2018-07-09 | 2019-03-29 | 彭盛 | 一种稳定的载氧微泡及其制备方法和应用 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999013916A2 (en) * | 1997-09-18 | 1999-03-25 | Nycomed Imaging As | Methods and compositions for medical imaging |
| MXPA05007730A (es) | 2003-02-04 | 2006-01-31 | Bracco Int Bv | Agentes de contraste para ultrasonido y proceso para la preparacion de los mismos. |
| JP5513708B2 (ja) | 2003-12-22 | 2014-06-04 | ブラッコ・シュイス・ソシエテ・アノニム | 造影イメージング用の気体封入マイクロベシクル・アセンブリー |
| JP4837663B2 (ja) * | 2004-08-18 | 2011-12-14 | ブラッコ・シュイス・ソシエテ・アノニム | 造影画像化のためのガス充填微小胞組成物 |
| US20110125080A1 (en) * | 2008-07-23 | 2011-05-26 | Koninklijke Philips Electronics N.V. | Ultrasound mediated drug delivery |
| CN107022020A (zh) | 2008-09-26 | 2017-08-08 | Ambrx公司 | 修饰的动物促红细胞生成素多肽和其用途 |
| CN113521317B (zh) * | 2021-07-01 | 2023-03-31 | 中国科学院深圳先进技术研究院 | 一种双靶向肿瘤的超声分子复合成像方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585112A (en) * | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
| DE4100470A1 (de) * | 1991-01-09 | 1992-07-16 | Byk Gulden Lomberg Chem Fab | Echokontrastmittel |
| EP1550464A1 (en) * | 1993-07-30 | 2005-07-06 | IMCOR Pharmaceutical Co. | Stabilized microbubble composition for ultrasound |
| GB9417941D0 (en) * | 1994-09-06 | 1994-10-26 | Nycomed Imaging As | Improvements in or relating to contrast agents |
-
1997
- 1997-01-22 GB GBGB9701237.1A patent/GB9701237D0/en active Pending
-
1998
- 1998-01-22 WO PCT/GB1998/000189 patent/WO1998032468A1/en active Application Filing
- 1998-01-22 JP JP53172098A patent/JP2001508454A/ja not_active Ceased
- 1998-01-22 CA CA002278750A patent/CA2278750A1/en not_active Abandoned
- 1998-01-22 CN CN 98801948 patent/CN1244131A/zh active Pending
- 1998-01-22 AU AU56740/98A patent/AU5674098A/en not_active Abandoned
- 1998-01-22 EP EP98900940A patent/EP0966305A1/en not_active Ceased
-
1999
- 1999-07-13 NO NO993438A patent/NO993438D0/no unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109529033A (zh) * | 2018-07-09 | 2019-03-29 | 彭盛 | 一种稳定的载氧微泡及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001508454A (ja) | 2001-06-26 |
| EP0966305A1 (en) | 1999-12-29 |
| GB9701237D0 (en) | 1997-03-12 |
| AU5674098A (en) | 1998-08-18 |
| NO993438L (no) | 1999-07-13 |
| WO1998032468A1 (en) | 1998-07-30 |
| NO993438D0 (no) | 1999-07-13 |
| CA2278750A1 (en) | 1998-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |