CN1235876C - Prepn of guanidyl thiocyanate - Google Patents
Prepn of guanidyl thiocyanate Download PDFInfo
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- CN1235876C CN1235876C CN 03158319 CN03158319A CN1235876C CN 1235876 C CN1235876 C CN 1235876C CN 03158319 CN03158319 CN 03158319 CN 03158319 A CN03158319 A CN 03158319A CN 1235876 C CN1235876 C CN 1235876C
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- Prior art keywords
- guanidine thiocyanate
- thiocyanate
- present
- weight
- guanidine
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Abstract
The present invention relates to a method for preparing chemical products, particularly to a method for preparing guanidine thiocyanate. The present invention comprises the following technological processes: a. melting; b. dissolution; c. filtration; d. dehydration; e. crystallization. Thus, high-purity guanidine thiocyanate is obtained. The present invention has the advantages of simple and practical technology and reasonable principle. The guanidine thiocyanate prepared by the method of the present invention has the advantages of good quality and high purity reach more than 99%, and is greatly popular with users.
Description
Affiliated technical field
The present invention relates to a kind of production method of Chemicals, especially the preparation method of guanidine thiocyanate.
Background technology
Guanidine thiocyanate, chemical name: thiocyanic acid imido urea, English name: Guanidine thio cyanate salt, its molecular formula is: (NH
2)
2C:NHHSCN (118.2).Be the white crystals body, 116～121 ℃ of fusing points, in the time of 20 ℃, the pH value of 6mol/L in water is 4.5～6, solubleness is dissolving fully.Can be used as biochemical reagents, medicine intermediate.Be used for the oil prodution industry degreasing, the strong fat degradation agents of conduct in the daily-use chemical industry, the membranolysis agent in the bio-pharmaceuticals.Its structural formula is:
Present production technique, the product purity that obtains are not very high, and in use, some occasion is just very high to the purity requirement of guanidine thiocyanate.
Summary of the invention
In order to overcome existing guanidine thiocyanate preparation method's deficiency, the invention provides a kind of method, this method can obtain highly purified guanidine thiocyanate.
The technical solution adopted for the present invention to solve the technical problems is: a kind of guanidine thiocyanate preparation method has following technical process:
A, be that 2: 1 Guanidinium carbonate and ammonium thiocyanate put into reactor with weight ratio, 50～90 ℃ of reactions 2 hours down, the guanidine thiocyanate crude product;
B, dissolving, at normal temperatures, the guanidine thiocyanate crude product is water-soluble by weight 1: 1 ratio;
C, filtration are removed impurity such as raw material and reaction by-product with filtering method;
D, dehydration are at high temperature dewatered the mother liquor after filtering;
E, crystallization, supersaturated solution cooling, condensing crystal has obtained purity greater than 99% guanidine thiocyanate.
Further: again through b, c, d, e step, is 1: 1 with the part by weight of water in the b step with the guanidine thiocyanate after the e step wherein, for drawing purity greater than 99.9% guanidine thiocyanate, can repeatedly repeat this step.
Its reaction formula is:
Features simple and practical process of the present invention, principle is reasonable, and with the guanidine thiocyanate of the inventive method preparation, quality is good, and the purity height can reach 99.9%, is highly commended by customers deeply.
Embodiment
A kind of guanidine thiocyanate preparation method has following technical process: a, is that 2: 1 Guanidinium carbonate and ammonium thiocyanate put into reactor with weight ratio, 50～90 ℃ of reactions 2 hours down, the guanidine thiocyanate crude product;
B, dissolving, at normal temperatures, the guanidine thiocyanate crude product is water-soluble by weight 1: 1 ratio;
C, filtration are removed impurity such as raw material and reaction by-product with filtering method;
D, dehydration are at high temperature dewatered the mother liquor after filtering;
E, crystallization, supersaturated solution cooling, condensing crystal has obtained purity greater than 99% guanidine thiocyanate.
Further: again through b, c, d, e step, is 1: 1 with the part by weight of water in the b step with the guanidine thiocyanate after the e step wherein, for drawing purity greater than 99.9% guanidine thiocyanate, can repeatedly repeat this step.
Claims (2)
1. guanidine thiocyanate preparation method is characterized in that having following technical process:
A, be that 2: 1 Guanidinium carbonate and ammonium thiocyanate put into reactor with weight ratio, 50～90 ℃ of reactions 2 hours down, the guanidine thiocyanate crude product;
B, dissolving, at normal temperatures, the guanidine thiocyanate crude product is water-soluble by weight 1: 1 ratio;
C, filtration are removed impurity such as raw material and reaction by-product with filtering method;
D, dehydration are at high temperature dewatered the mother liquor after filtering;
E, crystallization, supersaturated solution cooling, condensing crystal has obtained purity greater than 99% guanidine thiocyanate.
2. guanidine thiocyanate preparation method according to claim 1, it is characterized in that: with the guanidine thiocyanate after the e step again through b, c, d, e step, be 1: 1 with the part by weight of water in the b step wherein,, can repeatedly repeat this step for drawing purity greater than 99.9% guanidine thiocyanate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03158319 CN1235876C (en) | 2003-09-19 | 2003-09-19 | Prepn of guanidyl thiocyanate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03158319 CN1235876C (en) | 2003-09-19 | 2003-09-19 | Prepn of guanidyl thiocyanate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1526701A CN1526701A (en) | 2004-09-08 |
| CN1235876C true CN1235876C (en) | 2006-01-11 |
Family
ID=34287248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03158319 Expired - Fee Related CN1235876C (en) | 2003-09-19 | 2003-09-19 | Prepn of guanidyl thiocyanate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1235876C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112209856A (en) * | 2020-10-15 | 2021-01-12 | 苏州亚科科技股份有限公司 | Preparation method of guanidine thiocyanate |
-
2003
- 2003-09-19 CN CN 03158319 patent/CN1235876C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1526701A (en) | 2004-09-08 |
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| C14 | Grant of patent or utility model | ||
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| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |