CN1212120C - Ointment prescription for treating trauma - Google Patents
Ointment prescription for treating trauma Download PDFInfo
- Publication number
- CN1212120C CN1212120C CN 02115904 CN02115904A CN1212120C CN 1212120 C CN1212120 C CN 1212120C CN 02115904 CN02115904 CN 02115904 CN 02115904 A CN02115904 A CN 02115904A CN 1212120 C CN1212120 C CN 1212120C
- Authority
- CN
- China
- Prior art keywords
- ointment
- prescription
- treating
- milliliter
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002674 ointment Substances 0.000 title claims abstract description 13
- 208000014674 injury Diseases 0.000 title abstract 2
- 230000008733 trauma Effects 0.000 title abstract 2
- 206010052428 Wound Diseases 0.000 claims abstract description 19
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 19
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims abstract description 15
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims abstract description 6
- 229930182566 Gentamicin Natural products 0.000 claims abstract description 6
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 6
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract description 6
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims abstract description 6
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims abstract description 6
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 claims abstract description 6
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 6
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000012188 paraffin wax Substances 0.000 claims abstract description 6
- 239000008117 stearic acid Substances 0.000 claims abstract description 6
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 5
- -1 liquid paraffin Substances 0.000 claims abstract 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 claims description 5
- 229960001317 isoprenaline Drugs 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 230000023597 hemostasis Effects 0.000 abstract description 3
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 208000004210 Pressure Ulcer Diseases 0.000 abstract description 2
- 230000001954 sterilising effect Effects 0.000 abstract description 2
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 2
- IROWCYIEJAOFOW-UHFFFAOYSA-N DL-Isoprenaline hydrochloride Chemical compound Cl.CC(C)NCC(O)C1=CC=C(O)C(O)=C1 IROWCYIEJAOFOW-UHFFFAOYSA-N 0.000 abstract 1
- 229960005150 glycerol Drugs 0.000 abstract 1
- 229940093932 potassium hydroxide Drugs 0.000 abstract 1
- 229960004418 trolamine Drugs 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 description 1
- 229930182837 (R)-adrenaline Natural products 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 229960005139 epinephrine Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000003701 histiocyte Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides an ointment prescription for treating wounds, and relates to a medicine for treating trauma, particularly to an ointment for treating bedsores and other outer surface wounds. The ointment is mainly prepared from stearic acid, liquid paraffin, paraffin wax, glycerol, ethyl hydroxy benzoate, potassium hydroxide, trolamine, gentamycin sulfate and isoprenaline hydrochloride. The prescription of the present invention has reasonable combination and has the good effects of sterilization, antiinflammation, hemostasis, and wound surface nutrition and convergence. The ointment can be used for treatment simply and conveniently.
Description
Technical field
The present invention relates to treat the medicine of wound.Particularly a kind of unguentum for the treatment of decubital ulcer and other outer surface wound.
Technical background
Before the present invention proposes, the method of traditional treatment decubital ulcer is very numerous and diverse, particularly to II more than the phase than degree of depth wound surface, mostly adopt the roasting medicine of the topped back light of the big sliver of celebrating directly to stimulate wound surface, it is wayward to add roasting light temperature, greatly damage regenerated histiocyte, destroyed the healing of new wound surface again, the serious scald that also may cause skin and wound surface; Though traditional method is to the I phase or do not have the decubital ulcer of skin ulceration, by soak or massage certain effect is arranged, the nurse job amount is big.With oiliness paste application wound surface, pollute clothes and quilt easily, when changing dressings also difficulty clean up.
Summary of the invention
The purpose of this invention is to provide a kind of have sterilization, antiinflammatory, hemostasis, can grow the ointment prescription of wound surface growth and convergence wound surface, and easy to use, can reach good curative effect.
Realize that the concrete prescription components by weight percentage of purpose of the present invention is:
Stearic acid 35-45%
Liquid paraffin 18-20%
Paraffin 8-10%
Glycerol 25-30%
Ethyl hydroxybenzoate 0.1-0.3%
Potassium hydroxide 0.5-1%
Triethanolamine 0.03-0.06 milliliter
Gentamycin sulfate 0.2-0.33 milliliter (1 milliliter=40,000 unit)
Isoprenaline 0.1-0.4 milliliter
The present invention carries out routine with above-mentioned prescription and mixes, and promptly makes unguentum.
The present invention has demonstrated excellent curative in clinical, the pharmacology analysis from prescription of the present invention also can fully obtain proof:
1) isoprenaline is a B epinephrine variant excitomotor, peripheral blood vessel there is dilating effect, the energy microcirculation improvement, patients with bedsore mainly is that the long-term pressurized of the skin Zhou Xunhuan of place is obstructed, but with this medicine microcirculation improvement, increase oxygen supply and nutrition supply, recover the blood supply function of pressurized tissue.
2) gentamycin sulfate is a kind of spectrum antibiotics, and gram negative bacteria and gram-positive bacterium are had the strong antibiotic effect.
3) stearic acid, paraffin, glycerol, ethyl hydroxybenzoate, triethanolamine etc. can replenish the supply effect to skin-nourishing.
4) can improve the performance of various medicines after above several drugs is prepared mutually, thereby play the effect of rapid antiinflammatory, antiinflammatory, hemostasis, nutrition supply, promote the absorption of skin, the infection of control wound surface, make the blood circulation of wound surface be able to rapid change, convergence fast, the regeneration capacity of recovery skin.
The specific embodiment
By prescription provided by the invention, preparation 10 gram wound unguentum.
Stearic acid 4 grams
Liquid paraffin 2 grams
Paraffin 1 gram
Glycerol 2.5 grams
Ethyl hydroxybenzoate 0.03 gram
Potassium hydroxide 0.1 gram
0.05 milliliter of triethanolamine
0.3 milliliter of gentamycin sulfate
0.2 milliliter of isoprenaline
After above-mentioned prescription weighing, fully mix, promptly make the wound unguentum.
Claims (1)
1, a kind of unguentum for the treatment of wound, it is made up of stearic acid, liquid paraffin, paraffin, glycerol, ethyl hydroxybenzoate, potassium hydroxide, triethanolamine, gentamycin sulfate, isoprenaline, it is characterized in that: preparation 10 restrains the wound unguentum and is,
Stearic acid 4 grams,
Liquid paraffin 2 grams,
Paraffin 1 gram,
Glycerol 2.5 grams,
Ethyl hydroxybenzoate 0.03 gram,
Potassium hydroxide 0.1 gram,
0.05 milliliter of triethanolamine,
0.3 milliliter of gentamycin sulfate, 1 milliliter=40,000 units,
0.2 milliliter of isoprenaline.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02115904 CN1212120C (en) | 2002-05-30 | 2002-05-30 | Ointment prescription for treating trauma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02115904 CN1212120C (en) | 2002-05-30 | 2002-05-30 | Ointment prescription for treating trauma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1385161A CN1385161A (en) | 2002-12-18 |
| CN1212120C true CN1212120C (en) | 2005-07-27 |
Family
ID=4743940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02115904 Expired - Fee Related CN1212120C (en) | 2002-05-30 | 2002-05-30 | Ointment prescription for treating trauma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1212120C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050155763A1 (en) | 2004-01-16 | 2005-07-21 | Reddy B. R. | Settable fluids comprising particle-size distribution-adjusting agents and methods of use |
-
2002
- 2002-05-30 CN CN 02115904 patent/CN1212120C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1385161A (en) | 2002-12-18 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050727 Termination date: 20140530 |