CN120203866A

CN120203866A - Stent graft and stent delivery system

Info

Publication number: CN120203866A
Application number: CN202311838049.XA
Authority: CN
Inventors: 唐江峰; 唐本平
Original assignee: Lifetech Scientific Shenzhen Co Ltd
Current assignee: Lifetech Scientific Shenzhen Co Ltd
Priority date: 2023-12-27
Filing date: 2023-12-27
Publication date: 2025-06-27
Also published as: WO2025139929A1

Abstract

The invention provides a covered stent and a stent conveying system, wherein the covered stent comprises a main body stent with a tubular main body, the main body stent axially comprises a proximal end supporting section and a tumor cavity covered film section, a first embedded stent and a second embedded stent which are radially arranged are arranged in the tumor cavity covered film section, an opening communicated with the outside is arranged at the distal end of the tumor cavity covered film section, the distal ends of the first embedded stent and the second embedded stent are communicated with the opening, the supporting strength of the first embedded stent is larger than that of the second embedded stent, the first embedded stent with larger supporting strength is arranged to at least ensure the trafficability of an external iliac channel opposite to the first embedded stent when the covered stent is pressed, and further, the arrangement of the covered film which is prolonged by the first embedded stent and the second embedded stent can ensure the sealing performance at the joint gap position after being sutured with the main body stent and avoid the internal leakage at the joint gap position of the embedded stent.

Description

Tectorial membrane support and support conveying system

Technical Field

The invention relates to the technical field of medical equipment, in particular to a covered stent and a stent conveying system.

Background

The iliac artery, one of the important vascular systems in the human body, originates from the last segment of the abdominal aorta. It is divided into left and right common iliac arteries, passes through the fourth segment of the lumbar spine, extends down the spine on the medial side of the lumbar muscle, and finally into internal iliac arteries and external iliac arteries. The internal iliac arteries are responsible for supplying oxygen and nutrients to the pelvis and lower extremities, while the external iliac arteries supply blood to the ilium and its surrounding tissues. However, the existing iliac bifurcation stent has a series of problems such as easy closing of the internal iliac artery opening by blood vessels, easy occurrence of tortuosity and discounting of the internal iliac bifurcation to cause blockage, and possible blockage of the internal iliac bifurcation opening when the stent is slightly moved or rotated during operation.

To solve the above-mentioned problems, in the prior art, an embedded branch stent is purposefully designed, wherein a first branch is used for connecting an external iliac artery, and a second branch is used for connecting an internal iliac artery. The innovative structural design has wide patient applicability, can be expanded to the proximal side of the iliac bifurcation without being limited by the length of the common iliac artery, and is suitable for treating internal iliac arteries and external iliac arteries with various diameters. The innovative structure ensures that the stent is easier to align when being implanted, avoids the trouble of the ilium bifurcation stent, and further facilitates the insertion of the inner ilium stent and the outer ilium stent.

However, the embedded branched stent still presents some challenges in design, especially in the occurrence of endoleaks that may occur at the embedded stent.

Disclosure of Invention

Based on this, it is necessary to provide a new stent graft and stent delivery system to at least address the problem of endoleak of an embedded stent within a main body stent.

The tectorial membrane support comprises a main body support with a tubular main body, wherein the main body support comprises a proximal end supporting section and a tumor cavity tectorial membrane section, the distal end of the proximal end supporting section is connected with the proximal end of the tumor cavity tectorial membrane section, the proximal end section comprises a supporting wave ring, a first embedded support and a second embedded support which are radially arranged are arranged in the tumor cavity tectorial membrane section, an opening communicated with the outside is formed in the distal end of the tumor cavity tectorial membrane section, the distal ends of the first embedded support and the second embedded support are communicated with the opening, and the supporting strength of the first embedded support is larger than that of the second embedded support.

In one embodiment, the first and second embedded stents comprise a mesh body on which the wire diameter of the first embedded stent is greater than the wire diameter of the second embedded stent and/or the mesh density of the first embedded stent is greater than the mesh density of the second embedded stent.

In one embodiment, the distal ends of the first and second embedded brackets are provided with first and second distal bezel, respectively, and the first and second distal bezel are disposed away from each other.

In one embodiment, the proximal ends of the first embedded bracket and the second embedded bracket are respectively provided with a first proximal flat and a second proximal flat, or the proximal ends of the first embedded bracket and the second embedded bracket are respectively provided with a first proximal bevel and a second proximal bevel, and the first proximal bevel and the second proximal bevel are arranged oppositely.

In one embodiment, the stent graft further comprises a transition section connected between the proximal support section and the tumor lumen stent graft, the transition section being provided with a transition stent.

In one embodiment, a first covering film is arranged on the surface of the first embedded bracket, a second covering film is arranged on the surface of the second embedded bracket, and at least part of the first covering film and the second covering film extend outwards at the proximal ports of the first embedded bracket and the second embedded bracket respectively to form a connecting part, and the connecting part is connected with the tumor cavity covering film section.

In one embodiment, the connection portion of the first cover film is connected with the connection portion of the second cover film.

In one embodiment, the first cover film and the second cover film are integrally formed.

In one embodiment, the first distal bezel and the second distal bezel each include a major axis sidewall and a minor axis sidewall in a circumferential direction, an axial extension length of the major axis sidewall is greater than an axial extension length of the minor axis sidewall, the major axis sidewalls of the first and second embedded brackets are disposed in close proximity to each other, and a hook portion for hooking is provided at a distal end of at least one of the major axis sidewalls.

In one embodiment, the support band includes at least one anchoring band, and a plurality of anchoring barbs are circumferentially disposed on an outer side of the anchoring band.

A stent delivery system includes the stent graft.

The invention has the advantages that the invention provides the tectorial membrane bracket and the bracket conveying system, the tectorial membrane bracket comprises a main body bracket with a tubular main body, the main body bracket axially comprises a proximal end supporting section and a tumor cavity tectorial membrane section, a first embedded bracket and a second embedded bracket which are arranged along the radial direction are arranged in the tumor cavity tectorial membrane section, the distal end of the tumor cavity tectorial membrane section is provided with an opening communicated with the outside, the distal ends of the first embedded bracket and the second embedded bracket are communicated with the opening, the supporting strength of the first embedded bracket is larger than that of the second embedded bracket, the first embedded bracket with larger supporting strength is arranged to at least ensure the trafficability of an external iliac channel corresponding to the first embedded bracket when the tectorial membrane bracket is pressed, and further, the first embedded bracket and the second embedded bracket are arranged in an extending tectorial membrane, so that the sealing performance of the joint gap position after being sewed with the main body bracket can be ensured, and the internal leakage at the position of the embedded bracket is avoided.

Drawings

FIG. 1 is a schematic view of a stent graft in embodiment 1 of the present invention;

FIG. 2 is a schematic view showing the internal structure of a stent graft according to embodiment 1 of the present invention;

FIG. 3 is a schematic view showing the wire diameter distribution of a first stent and a second stent according to embodiment 1 of the present invention;

FIG. 4 is a graph showing the distribution of the mesh density of the first and second embedded scaffolds in examples 1 and 2 of the present invention;

FIG. 5 is a schematic view of proximal flat openings of a first and a second embedded stent according to embodiment 2 of the present invention;

FIG. 6 is a schematic view showing the development structures of the first and second embedded brackets in embodiment 2 of the present invention;

fig. 7 is a schematic structural view of a hook portion in a stent graft in embodiment 2 of the present invention;

Fig. 8 is a schematic view of a blocking member provided on the hook portion in embodiment 2 of the present invention;

fig. 9 is a schematic view showing a developing structure of a hook stopper in embodiment 2 of the present invention;

FIG. 10 is a schematic view of a transition support in the embodiment 2 of the present invention with a special-shaped wave ring;

FIG. 11 is a schematic view of a distal end high wave of a profiled wave ring in embodiment 2 of the present invention;

FIG. 12 is a schematic view showing the tapering of the distal high wave of the profiled wave ring in embodiment 2 of the present invention;

FIG. 13 is a schematic view showing a transition support according to embodiment 2 of the present invention comprising a wave ring support;

FIG. 14 is a schematic view showing a transition stent according to embodiment 2 of the present invention comprising a mesh stent;

FIG. 15 is a schematic view showing the structure of the first and second films in embodiment 3 of the present invention;

Fig. 16 is a schematic view showing the structure of a connecting portion of the first and second films in embodiment 3 of the present invention;

FIG. 17 is a top view of the stent graft of example 3 of the present invention with the attachment portion of the first and second stents attached to the luminal stent section;

FIG. 18 is a schematic view showing the connection structure of the first and second films according to embodiment 3 of the present invention;

FIG. 19 is a top view of the stent graft of example 3 of the present invention when the first and second stents are connected to the luminal stent section by a connecting portion;

FIG. 20 is a schematic view of an integrated structure of a first film and a second film in embodiment 3 of the present invention;

FIG. 21 is a top view of the stent graft of embodiment 3 of the present invention with the integrally formed first and second stents connected to the tumor lumen stent segments;

FIG. 22 is a schematic diagram of the structure of an intermediate anchoring band in embodiment 4 of the present invention;

Fig. 23 is a schematic view showing a hooking structure of the stent graft in the conveyor in embodiment 5 of the present invention.

Detailed Description

In order that the inventive concept may be better understood, a detailed description of embodiments of the application will be presented below, taken in conjunction with the drawings, and the following detailed examples are merely illustrative of, and not limiting of, the application.

For ease of description, spatially relative terms, such as "inner," "outer," "lower," "below," "upper," "above," and the like, may be used herein to describe one element or feature's relationship to another element or feature as illustrated in the figures. Such spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "over" the other elements or features. Thus, the example term "below" may include both upper and lower orientations. The device may be otherwise oriented (rotated 90 degrees or in other directions) and the spatial relative relationship descriptors used herein interpreted accordingly.

Although the terms first, second, third, etc. may be used herein to describe various elements, components, regions, layers and/or sections, these elements, components, regions, layers and/or sections should not be limited by these terms. These terms may be only used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.

For purposes of more clarity in describing the structure of the present application, the terms "proximal" and "distal" are defined herein as terms commonly used in the interventional medical arts. Specifically, "distal" means the end of the blood vessel that is far from the heart, "proximal" means the end of the blood vessel that is near the heart, "axial" means the length direction thereof, "radial" means the direction perpendicular to the "axial direction," upper "and" lower "are the ends that are relatively far apart, and when one end is defined as" upper ", the other end that is far apart is" lower ".

Example 1

Referring to fig. 1 and 2, the present invention provides a covered stent 100, where the covered stent 100 is generally composed of a metal framework and a covered material, as shown in fig. 3, the metal framework may be in a zigzag wave or woven mesh design, the covered material has a certain blood flow isolation capability, and is combined with the metal framework by means of pressurizing, heating, suturing, etc. to form a complete covered stent 100, and the proximal end of the covered stent 100 is generally placed in or connected with the common iliac artery, and the diameter of the lumen is generally matched with the diameter of the common iliac artery. In this embodiment, the covered stent 100 comprises a main body stent 10 with a tubular main body, the surface of the main body stent 10 is provided with a surface covered film 31, the main body stent 10 comprises a proximal end supporting section 1 and a tumor cavity covered film section 3 along the axial direction, the distal end of the proximal end supporting section 1 is connected with the proximal end of the tumor cavity covered film section 3, the surface covered film 31 of the proximal end supporting section 1 and the surface covered film 31 of the tumor cavity covered film section 3 can be integrally formed in a single Zhang Fu film mode, and can also be spliced and formed in a suturing or bonding mode through a plurality of covered films, the proximal end section comprises a supporting wave ring 11, the tumor cavity covered film section 3 is only provided with the surface covered film 31, and a first embedded stent 4 and a second embedded stent 5 which are arranged along the radial direction are arranged in the tumor cavity covered film section 3, so that the main body stent 10 reduces the supporting wave ring 11 at the position of the tumor cavity covered film section 3 to promote the flexibility of the covered film stent 100 at the position of the tumor cavity, and simultaneously provides the supporting performance through the first embedded stent 4 and the second embedded stent 5, and simultaneously, when blood flows through the iliac cavity covered film 3 and the iliac cavity covered film, the iliac cavity covered film 3 is sewn or bonded to the first embedded stent and the second stent, and the blood is prevented from flowing to the external stent and the external stent, and the blood is prevented from flowing to the external stent, and the first and the internal stent and the external stent, and the blood stent are further, and the blood stent are prevented from flowing to the internal stent and the iliac cavity and the vascular stent.

In some embodiments, please continue to refer to fig. 2, the first embedded stent 4 and the second embedded stent 5 are both in a net-shaped main structure, so as to emphasize better shape support, the net-shaped main structure can have better film-covering tension, so that even if smaller woven wire diameters are provided, better film-covering tension can be provided to keep the shape of the blood path, and the net-shaped main structure can enable the external iliac stent and the internal iliac stent to have more contact positions between the embedded stent and the interposed stent when the first embedded stent 4 and the second embedded stent 5 are respectively interposed, so as to provide larger friction force, and the anchoring force and the attaching force between the stents can be effectively enhanced to provide the anti-slip performance of the stent.

In order to make the covered stent 100 provided by the application more preferentially emphasize the state of maintaining a passage leading to an external iliac blood vessel when being stressed, in the embodiment, the supporting strength of the first embedded stent 4 is higher than the supporting strength of the second embedded stent 5, wherein the supporting strength is expressed as that the integral deformation of the first embedded stent 4 and the second embedded stent 5 is smaller than the integral deformation of the second embedded stent 5 under the condition that the first embedded stent 4 and the second embedded stent 5 are subjected to the same pressure, so as to maintain a better passage state;

In this embodiment, referring to fig. 3 and 4, in order to make the external iliac channel and the internal iliac channel separated by the first embedded stent 4 and the second embedded stent 5 have the supporting strength distribution effect as described above, the wire diameter of the mesh body of the first embedded stent 4 may be larger than the wire diameter of the mesh body of the second embedded stent 5, and/or the mesh density of the first embedded stent 4 may be larger than the mesh density of the second embedded stent 5.

In one embodiment, referring to fig. 3, the mesh density of the first embedded stent 4 and the second embedded stent 5 is made uniform, so that the wire diameter of the mesh body of the first embedded stent 4 is larger than the wire diameter of the mesh body of the second embedded stent 5, so that the supporting strength of the first embedded stent 4 is larger than the supporting strength of the second embedded stent 5, where the larger stent wire diameter has small deformation capability and can provide higher supporting force when being pressed, so that by making the wire diameter of the first embedded stent 4 larger than the wire diameter of the second embedded stent 5, under the condition that the first embedded stent 4 and the second embedded stent 5 are pressed simultaneously, the wire diameter of the first embedded stent 4 is large, the deformation amount generated is small, and the second embedded stent 5 has relatively smaller wire diameter, the deformation amount generated is large, so that the first embedded stent 4 can maintain better iliac stent 100 to maintain the blood flow through the stent and further to the blood flow through the stent, and the blood flow through the vascular graft is ensured.

In another embodiment, referring to fig. 4, the wire diameters of the first embedded stent 4 and the second embedded stent 5 are made uniform, so that the mesh density of the mesh body of the first embedded stent 4 is greater than the mesh density of the mesh body of the second embedded stent 5, so that the supporting strength of the first embedded stent 4 is greater than the supporting strength of the second embedded stent 5; here, the first embedded stent 4 and the second embedded stent 5 comprise a mesh body with a plurality of mesh structures, wherein the higher the mesh density is, the higher the number of required supporting wires is, and the smaller the area of a single mesh is, the larger the supporting strength that can be provided by the larger mesh density is, in this embodiment, the first embedded stent 4 and the second embedded stent 5 have a diamond mesh structure, the first embedded stent 4 has a first diamond mesh, the second embedded stent 5 has a second diamond mesh, the first diamond mesh and the second diamond mesh have an upper vertex and a lower vertex in the axial direction, the left vertex and the right vertex are provided in the radial direction, the interval between the upper vertex and the lower vertex of the first diamond mesh is D1, the interval between the left vertex and the right vertex is L1, the interval between the upper vertex and the lower vertex of the second diamond mesh is D2, and the interval between the left vertex and the right vertex is L2, preferably, both D1 and L1 are smaller than D2 and L2, so that the single diamond mesh has a larger area than the first diamond mesh and the first diamond mesh has a larger area than the first diamond mesh, and the first diamond mesh has a larger area than the first diamond-shaped stent, and the first diamond-shaped stent has a larger area than the first diamond-shaped support, and has a larger area than the first diamond-shaped support.

In some embodiments, referring further to fig. 4, at least L1 of the first diamond grid is made smaller than L2 of the second diamond grid, so that the density of the first diamond grid is changed only in the circumferential direction of the first embedded stent 4, so that the density of the first diamond grid can be increased at least in the radial direction, thereby achieving the effect of enhancing the supporting strength in the radial direction.

In one embodiment, the wire diameter of the first embedded stent 4 is larger than the wire diameter of the second embedded stent 5 and the grid density of the first embedded stent 4 is larger than the grid density of the second embedded stent 5, so that the wire diameter and the grid density of the first embedded stent 4 and the second embedded stent 5 can be set at the same time, the first embedded stent 4 and the second embedded stent 5 can form a difference of supporting strength, and reasonable wire diameter size and grid density distribution can be formed, so that too small or too large flexibility of the first embedded stent 4 and the second embedded stent 5 caused by too small wire diameter setting and grid density setting can be avoided, folding and unfolding performances of the covered stent 100 are affected, and assembly difficulty and release difficulty of the covered stent 100 in a sheath tube are caused.

In this embodiment, the supporting strength is specifically expressed as the deformation of the integral tubular inner cavity after the first embedded bracket 4 and the second embedded bracket 5 are pressed, that is, under the same stress condition, the first embedded bracket 4 and the second embedded bracket 5 are compressed by the radial force tester by using the same force (the force needs to enable the first embedded bracket 4 and the second embedded bracket 5 to generate a certain amount of deformation), the outer side walls of the first embedded bracket 4 and the second embedded bracket 5 are pressed, the radial cross-sectional areas of the first embedded bracket 4 and the second embedded bracket 5 after the pressing are measured and calculated, the bracket with the large total cross-sectional area measured after the pressing has larger supporting strength, and the bracket with the smaller total cross-sectional area has smaller supporting strength.

Example 2

In this embodiment, please continue to refer to fig. 4, the main body stent 10 of the stent graft 100 and the first and second embedded stents 4 and 5 are substantially the same as those in embodiment 1, except that the opening 32 of the stent graft 100 at the distal end is set as an inclined opening, specifically, the distal ends of the first and second embedded stents 4 and 5 are respectively provided with a first distal inclined opening 41 and a second distal inclined opening 51, and the first distal inclined opening 41 and the second distal inclined opening 51 are disposed away from each other, where the distal ends of the first and second embedded stents 4 and 5 are the access openings when the outer and inner iliac stents are inserted, and the distal ends of the two embedded stents are set as inclined openings, firstly, in order to increase the size of the opening 32 when the outer and inner iliac stents are inserted, thereby reducing the difficulty when the stent is inserted, and secondly, since in the present application, the connection with the outer and inner iliac artery is established by the additional outer and inner iliac stents, the two inner iliac stents are further separated from each other by the first and second inclined stents and the second inclined brackets, and the two inner iliac stents are further prevented from being further affected by the two side of the two inner stents and the two inner iliac stents and the inner stents are disposed away from each other, thereby the two side of the two inner stents can be more easily separated from each other.

Referring to fig. 4 and 5, the proximal end positions of the first embedded bracket 4 and the second embedded bracket 5 may be set to be flat or inclined, specifically, the proximal ends of the first embedded bracket 4 and the second embedded bracket 5 may be respectively provided with a first proximal flat 43 and a second proximal flat 53, where, in order to form a double-layer bracket when the first embedded bracket 4 and the second embedded bracket 5 are set, the whole volume of the compressed and sheathed bracket is reduced, and the first proximal flat 43 and the second proximal flat 53 may be set in a dislocation manner in an axial direction so as to be located at different axial positions after compression, thereby avoiding the overlarge volume and difficult sheath loading caused by stacking at one axial position.

In another embodiment, referring further to fig. 4, the first proximal inclined port 42 and the second proximal inclined port 52 are disposed at the proximal ends of the first embedded stent 4 and the second embedded stent 5, respectively, and the first proximal inclined port 42 and the second proximal inclined port 52 are disposed opposite to each other, where the two inclined ports form a V-shaped section on an axial tangential plane, the first proximal inclined port 42 and the second proximal inclined port 52 are blood flow access ports in the tumor cavity covered section 3, the inclined port structure is configured to increase the area of the blood flow receiving ports so as to ensure the smoothness of the blood flow, and further, the first proximal inclined port 42 and the second proximal inclined port 52 are disposed opposite to each other, so that the higher side wall of the inclined port is close to the side wall of the tumor cavity covered section 3, thereby avoiding vibration or oscillation during blood flushing and reducing the smoothness of the blood flow, in some embodiments, the first proximal inclined port 42 and the first distal inclined port 41, the second proximal inclined port 52 and the second inclined port 52 are disposed at the same angle as the first inclined port 5, so that the second side wall of the second embedded stent 5 can be disposed in parallel to the side wall of the sheath 5, and the second embedded stent 5 can be further disposed in the side wall of the stent, and the side wall of the sheath 5 can be further displaced, and the side wall of the stent is further displaced in the side.

Here, the arrangement of the first proximal bezel 42 and the second proximal bezel 52 also allows for a larger access opening for other stents to be implanted, thereby reducing the difficulty of implantation and improving the efficiency of the procedure.

Referring to fig. 6, in order to easily identify the positions of the first embedded stent 4 and the second embedded stent 5 in the blood vessel after the covered stent 100 is inserted into the human body, the proximal ports and the distal ports of the first embedded stent 4 and the second embedded stent 5 are respectively provided with a developing structure 6, where the developing structure 6 may be a single developing ring adapted to the shapes of the proximal ports and the distal ports of the first embedded stent 4 and the second embedded stent 5, and connected to the edges of the proximal ports and the distal ports by braiding or winding, and the developing ring may be made of platinum wire or tantalum metal.

In other embodiments, referring to fig. 7, the first distal bezel 41 and the second distal bezel 51 may have a larger inclination angle than the first proximal bezel 42 and the second proximal bezel 52, where, since the first distal bezel 41 and the second distal bezel 51 are disposed away from each other, the two brackets form a V-shaped tip protruding in the distal direction at the mutually abutting position, and the V-shaped tip may be used for hooking and connecting with the conveyor for pushing and controlling when the stent graft 100 of the present application is conveyed in the conveyor; specifically, the first distal bevel 41 and the second distal bevel 51 each circumferentially comprise a long axis side wall 501 and a short axis side wall 502 to form a bevel structure, the axial length of the long axis side wall 501 is greater than that of the short axis side wall 502, the long axis side walls 501 of the first embedded stent 4 and the second embedded stent 5 are closely attached to each other, a V-shaped tip is formed at the distal end, the length of the V-shaped tip in the axial direction is longer than any other position of the distal end of the stent graft 100, so that a hooking portion 503 for hooking is provided at the distal end of the long axis side wall 501, the hooking portion 503 can be better hooked by the hooked member 2001, and the hook is prevented from affecting or contacting other positions of the stent graft 100, wherein the inclination angle of the first distal bevel 41 and the second distal bevel 51 can be set to 30 DEG to 60 DEG, in consideration of the matching requirements of the distal clamping and releasing structure of the stent graft, less than 30 DEG may cause the stent graft to be unable to be effectively clamped, thereby affecting the operation, conversely, if greater than 60 DEG may cause an excessive angle, may cause the stent to be prevented from extending to an external iliac artery to a small diameter when the stent is not necessary to be implanted outside an artery, and the stent is prevented from extending to a small diameter when the external vessel is considered, in addition, unnecessary stent length extension may increase the difficulty of the procedure, which may result in difficult release of the stent graft 100, thereby affecting the smooth performance of the procedure.

Referring to fig. 8 and 9, the hooking portion 503 may be disposed only on the long axis side wall 501 of the first distal end bevel 41 of the mesh body of the first embedded bracket 4 or only on the long axis side wall 501 of the second distal end bevel 51 of the mesh body of the second embedded bracket 5, the distal end bevel of at least one embedded bracket is provided with a hooking portion 503 to form a hooking position for hooking, wherein in some embodiments, the hooking portion 503 may also be formed by a grid structure of the long axis side wall 501 of the first distal end bevel 41 of the mesh body of the first embedded bracket 4 and the long axis side wall 501 of the second distal end bevel 51 of the second embedded bracket 5, the distal end side of the blocking portion 503 includes at least one blocking member 5031 for hooking, wherein the blocking member 5031 may be a wire of the grid structure, or a developing ring at the first distal end bevel 41 and the second bevel 51, the number of brackets at the position may be reduced only by the blocking effect provided by the developing ring, so that the bracket 503 may be easily released from the grid structure of the first distal end bevel 41 and the second bevel 51 may be further provided with a blocking member 5031 for preventing the hook film 2001 from being completely released from the hook structure from the long axis side wall 501.

In this embodiment, referring further to fig. 1 and 10, since the proximal support section 1 and the first and second embedded stents 4 and 5 in the tumor cavity stent-graft section 3 have different stent structures, the mutation and fault of the structure can occur at the connection position of different sections, which is unfavorable for the long-term use of the bracket, in order to make the transition between the proximal support section 1 of the stent graft 100 and the tumor cavity stent section 3 smoother, a transition section 2 is arranged between the proximal end supporting section 1 of the main body bracket 100 and the tumor cavity tectorial membrane section 3, the transition section 2 is provided with a transition bracket 21, the transition section 2 and the transition bracket 21 are arranged between the proximal end supporting section 1 and the tumor cavity tectorial membrane section 3, two parts for the transition body mount 10; wherein, when the proximal ports of the first embedded bracket 4 and the second embedded bracket 5 are the first proximal flat 43 and the second proximal flat 53 respectively, the transition support 21 may be one of the support collars 11 of the proximal support section 1, the proximal end of the transition support 21 being flush with the distal flat mouth of the proximal section, the distal end of the transition support 21 being flush with the proximal flat mouths of the first and second embedded supports 4, 5; here the number of the elements is the number, because the surface coating 31 of the tumor cavity coating section 3 is tightly clung to the outer surfaces of the first embedded bracket 4 and the second embedded bracket 5 after being sewed with the first embedded bracket 4 and the second embedded bracket 5, the first and second in-line brackets 4 and 5 have a longer length direction and a shorter width direction after being disposed side by side, in the width direction, the width of the tumor cavity tectorial membrane section 3 is smaller than the diameter of the proximal support section 1, so the transition support 21 has a circular cross section at the proximal end, while the distal end has a flat strip-shaped cross-section with at least one side of reduced width, and the transition support 21 has a tapered configuration from the proximal end to the distal end.

In another embodiment, referring to fig. 10 and 11, when the proximal ports of the first embedded stent 4 and the second embedded stent 5 are the first proximal bevel 42 and the second proximal bevel 52, respectively, the two bevel forms a V-shaped section tumor cavity coated section 3 on an axial tangential plane to form an unsupported area at the position, wherein the proximal end of the transition stent 21 is flush with the flat distal end of the proximal section, the distal end of the transition stent 21 is flush with the V-shaped dual bevel formed by the first embedded stent 4 and the second embedded stent 5, the transition stent 21 is capable of supporting the surface coated film 31 of the unsupported area formed between the dual bevel, thereby avoiding collapse or poor release caused by the lack of a supporting structure at the position of the tumor cavity coated section 3, the transition stent 21 can be a profiled wave ring 211, the distal end portion of the profiled wave ring 211 extends into the unsupported area of the tumor cavity coated section 3, the proximal end of the specific profiled wave ring 211 has a uniform high-like proximal end with a plurality of high-end peaks 1, the high-end peaks at least two high-end peaks at the distal end of the profiled wave ring 211 and the distal end 2112 is provided with a plurality of high-end peaks at the distal end 2112, the distal end 2112 is provided near the apex at the distal end 2112, and the distal end 2112 is provided near the distal end of the two high-end of the proximal end 2112, and the apex 2112 is provided near the apex at the apex 2112, and the distal end of the two high-end of the tapered stent 2112 is provided.

Further, referring to fig. 12, a plurality of distal end high waves 2112 of the profiled wave ring 211 may be further provided, and peak-shaped structures with highest middle wave height and gradually lower wave heights towards two sides are formed at opposite sides of the distal end of the profiled wave ring 211 respectively so as to adapt to the shape of the unsupported region, wherein the profiled wave ring 211 can avoid local collapse or release of the unsupported region due to the lack of the supporting structure to affect the blood circulation, and meanwhile, the structure of the profiled wave ring 211 extending between the proximal end supporting distal end section and the tumor cavity tectorial membrane section 3 can enable the connection force of the tectorial membrane stent 100 between the proximal end supporting section 1 and the tumor cavity tectorial membrane section 3 to be more sufficient, so that the stent integrity is higher, thereby avoiding the situation of bending at the transition position between the tumor cavity section and the proximal end section.

In some embodiments, referring to fig. 13-14, the transition support 21 includes a band support 212 and/or a mesh support 213, where when the proximal ports of the first embedded support 4 and the second embedded support 5 are the first proximal flat 43 and the second proximal flat 53, respectively, the transition support 21 may be an annular band support 212, and when the proximal ports of the first embedded support 4 and the second embedded support 5 are the first proximal diagonal 42 and the second proximal diagonal 52, respectively, the transition support 21 may include a band support 212, such as the aforementioned shaped band, and not described herein, and may also include a band support 212 and a mesh support 213, in which the band support 212 is configured to be in close proximity to the support band 11 of the proximal support section 1, so as to provide better engagement with the proximal support section 1 at that location, thereby improving the overall compliance of the stent graft 100, and in which the mesh support 213 is configured to have a mesh weave structure or a cut-out structure, and in which the mesh support 213 is configured to have a mesh weave structure, such that the mesh support 213 is configured to be in close proximity to the inner wall of the first embedded support 4 and the second embedded support section 1, thereby ensuring a better overall compliance with the lumen of the lumen.

Example 3

In this embodiment, please refer to fig. 15-17, the main body stent 10 of the stent graft 100 and the first stent graft 4 and the second stent graft 5 have the same structure as that of embodiment 1, except that the surfaces of the first stent graft 4 and the second stent graft 5 are respectively provided with a first stent graft 401 and a second stent graft 504, in order to further connect the first stent graft 4 and the second stent graft 5 to the lumen surface of the lumen graft segment 3, the stent graft is tightly connected to the lumen surface of the lumen graft segment 3 at the proximal end position, the first stent graft 401 is prevented from leaking from the lumen graft segment 3 at least partially at the proximal end of the first stent graft 4, the second stent graft 504 is formed at least partially at the proximal end of the second stent graft 5 to form a connecting portion 402, the connecting portion 402 is formed beyond the proximal end of the first stent graft 4 and the second stent graft 5, so that the lumen graft 4 and the second stent graft 5 are tightly adhered to the lumen segment 3 at the proximal end of the lumen graft segment 4, and the lumen segment 5 are formed at the proximal end of the lumen segment 4, and the lumen segment 5 are completely adhered to each other, the seam is cut-off between the lumen segment 4 and the lumen segment 4 is ensured, the seam of the seam position that tumour chamber tectorial membrane section 3 and first embedded support 4 and second embedded support 5 formed often is difficult to reach closely laminating effect, so the connecting portion 402 of outwards extending is located at least on one side of the mutual laminating position of the nearly port of first embedded support 4 and second embedded support 5 to at least, cover two laminating seams 4021 of tangent position formation of hugging closely of two supports, replace the mode of directly connecting the shutoff with tumour chamber tectorial membrane section 3 through the mode of tectorial membrane cover shutoff and reach better seam shutoff effect.

In some embodiments, please continue to refer to fig. 17, the outwardly extending connection portion 402 is disposed along the circumferential directions of the proximal ends of the first embedded bracket 4 and the second embedded bracket 5, so that, except for the two fitting gaps 4021 formed at the close-contact positions of the first embedded bracket 4 and the second embedded bracket 5, any positions of the first embedded bracket 4 and the second embedded bracket 5, which are connected with the tumor cavity tectorial membrane section 3, can be further sealed by secondary connection of the connection portion 402, so as to avoid internal leakage.

In this embodiment, the first film 401 and the second film 504 are different from the surface film 31 of the main body stent 10, and the surface film 31 is a PET film in this embodiment. The first covering film 401 and the second covering film 504 are both ePTFE films, the PET films have the characteristic of high strength, the ePTFE films are weak in strength and smooth in surface and are not easy to form thrombus, long-term smoothness of small-sized blood vessels is good, pores are small, the PET films and the ePTFE films are combined for use, the integral strength of the stent covering film is ensured in the main body stent 10, the first embedded stent 4 and the second embedded stent 5 have better blood flow isolation effect in the tumor cavity covering film section 3, and the smoothness of long-term branching is ensured, namely, the plugging effect is good.

In this embodiment, the second covering film 504 is disposed, so that the first embedded bracket 4 and the second embedded bracket 5 are effectively isolated, and when the guide wire is led into the first embedded bracket 4 or the second embedded bracket 5, the guide wire cannot pass through the first embedded bracket 4 or the second embedded bracket 5, so that the guide wire is ensured to be accurately led into the corresponding inner cavity bracket, and the problem that the implanted branch bracket cannot reach the designated embedded bracket is avoided.

In another embodiment, referring to fig. 18 and 19, in order to ensure the tightness of the whole connection portion 402 and the tumor cavity covering film section 3 after connection, the connection portion 402 of the first covering film 401 and the connection portion 402 of the second covering film 504 are connected, and then the two connection portions 402 and the tumor cavity covering film section 3 are respectively connected after connection, so that the proximal ports of the first embedded bracket 4 and the second embedded bracket 5 are integrated through the connection portion 402, and the peripheral edges of the proximal ports of the first embedded bracket 4 and the second embedded bracket 5 are enclosed and sealed in the circumferential direction of the proximal ports before the first embedded bracket 4 and the second embedded bracket 5 enter the tumor cavity covering film section 3 and are connected with the tumor cavity covering film section 3, thereby achieving better edge sealing and inner leakage preventing effects after the first connection of the proximal ports and the second connection of the connection portion 402.

In other embodiments, referring to fig. 20 and 21, in order to further ensure tightness after the first and second embedded stents 4 and 5 are connected to the tumor cavity covered membrane section 3 at the proximal end position, the fitting gap 4021 between the first and second embedded stents 4 and 5 is not formed with an inner leak, the first and second covered membranes 401 and 504 of the first and second embedded stents 4 and 5 are formed integrally, where the integral forming means that the first and second covered membranes 401 and 504 are formed continuously by a single covered membrane, without bonding or stitching, the first and second embedded stents 4 and 5 having the first and second covered membranes 401 and 504 are formed integrally and are connected together at least at the proximal end mutually fitting side thereof by a covered membrane, where the first and second covered membranes 401 and 504 are formed continuously by a single covered membrane and are connected together at the proximal end mutually fitting side thereof by a covered membrane, and the first and second embedded stents 4 and the second covered membrane are not covered by a seal membrane at the proximal end position of the tumor cavity covered by an inner leak, and the blood blocking membrane 401 is prevented from being formed at the position of the first and second covered membrane section 401.

Example 4

In this embodiment, referring to fig. 1 and 22, the structures of the tumor cavity tectorial membrane section 3 and the first and second embedded stents 4 and 5 of the tectorial membrane stent 100 are substantially the same as those of embodiments 1-3, except that, in order to enhance the anchoring force of the proximal support section 1 in the blood vessel or other stent lumen, the support band comprises at least one anchoring band, where the support band 11 of the proximal support section 1 may comprise only one anchoring band 12, and a plurality of anchoring barbs 121 are provided on the outer side of the anchoring band 12 along the circumferential direction for enhancing the anchoring property of the proximal support section to the blood vessel wall or the stent inner side wall.

In some embodiments, a plurality of support bands 11 are axially arranged on a surface covering film 31 of a proximal support band 1, and the plurality of support bands 11 comprise at least one anchor band 12, the anchor band 12 is used for providing better anchoring effect with a blood vessel in the proximal support band 1, wherein the anchor band 12 is arranged between the support bands 11 of the proximal support band 1 at the proximal end and the support bands 11 at the distal end, a plurality of anchor barbs 121 are circumferentially arranged on the outer side, the anchor barbs 121 protrude from the outer side wall of the proximal support band 1 and incline and extend towards the distal direction, when the proximal support band 1 is released in the blood vessel, the support bands 11 provide supporting unfolding and anchoring force, the anchor barbs 121 of the intermediate support bands 11 are pricked into the blood vessel wall at the same time, further the anchor bands 12 are arranged between the support bands 11 of the proximal support band 1 at the proximal end and the support bands 11 at the proximal end and can be enhanced at the intermediate position of the proximal end, the anchor bands can be connected with the support bands 12 at the intermediate positions of the proximal support band 1, and the intermediate bands can be further connected with the support bands 11 at the intermediate positions at the proximal end and the intermediate positions, and the intermediate support bands can be further connected with the support bands 11 at the intermediate positions.

The design of the anchoring barbs 121 of the anchoring band 12 ensures that the proximal support section 1 of the covered stent 100 is not shifted or swayed when the external or internal ilium stent is further implanted in the covered stent 100 according to the application after being implanted in a blood vessel or other stent, because the anchoring barbs 121 enhance the anchoring force and the connecting force.

Example 5

In this embodiment, please refer to fig. 23, the main body stent 10 of the stent graft 100 and the first and second embedded stents 4 and 5 are generally the same as those in embodiments 1-4, and the stent delivery system 200 is further provided in this embodiment, wherein the stent delivery system 200 includes the stent graft 100 according to the foregoing embodiment and a conveyor for delivering the stent graft 100 to a designated vascular position and releasing the stent graft, wherein the conveyor generally includes a delivery sheath and a delivery handle for controlling the advancing and retreating of the delivery sheath to release the stent graft from the delivery sheath, the conveyor is further provided with a push rod 2002, a hook member 2001 is connected to a proximal end of the push rod 2002, the hook member 503 of the stent graft 100 is used for controlling the relative position of the stent graft 100 in the delivery sheath of the conveyor by the push rod 2002 after the hook member 2001 is connected, the hook member 2001 is switchable between an unlocked state and a locked state by controlling the hook member 2001, wherein the hook member 2001 is connected to the hook member 503 and the hook member 2001 is not in the unlocked state when the hook member 2001 is in the locked state, and the stent graft 100 is released from the hook member 2001.

The above specific embodiments are only some embodiments of the present invention, and not limiting, and the present disclosure is not intended to be exhaustive or to limit all embodiments of the inventive concept, and some features of the above different embodiments may be replaced with each other or combined, and those skilled in the art may simply replace the features according to the actual needs, so that the inventive concept is subject to the scope of protection claimed.

Claims

1. A coated stent, characterized in that it comprises a main body stent with a tubular body, the main body stent comprising a proximal support segment and a tumor cavity coated segment, the distal end of the proximal support segment is connected to the proximal end of the tumor cavity coated segment; the proximal segment comprises a supporting wave ring, the tumor cavity coated segment is provided with a first embedded stent and a second embedded stent arranged radially, the distal end of the tumor cavity coated segment is provided with an opening connected to the outside, the distal ends of the first embedded stent and the second embedded stent are both connected to the opening; the support strength of the first embedded stent is greater than the support strength of the second embedded stent.

2. The coated stent according to claim 1 is characterized in that the first embedded stent and the second embedded stent comprise a mesh body, on which the wire diameter of the first embedded stent is greater than the wire diameter of the second embedded stent, and/or the mesh density of the first embedded stent is greater than the mesh density of the second embedded stent.

3. The coated stent according to claim 1 is characterized in that the distal ends of the first embedded stent and the second embedded stent are respectively provided with a first distal oblique opening and a second distal oblique opening, and the first distal oblique opening and the second distal oblique opening are arranged to be opposite to each other.

4. The coated stent according to claim 3 is characterized in that the proximal ends of the first embedded stent and the second embedded stent are respectively provided with a first proximal flat opening and a second proximal flat opening; or the proximal ends of the first embedded stent and the second embedded stent are respectively provided with a first proximal oblique opening and a second proximal oblique opening, and the first proximal oblique opening and the second proximal oblique opening are arranged opposite to each other.

5. The coated stent according to claim 1 is characterized in that the coated stent also includes a transition section connected between the proximal support section and the tumor cavity coated section, and the transition section is provided with a transition stent.

6. The coated stent according to claim 1 is characterized in that a first coating is provided on the surface of the first embedded stent, and a second coating is provided on the surface of the second embedded stent, and the first coating and the second coating at least partially extend outward from the proximal ports of the first embedded stent and the second embedded stent, respectively, to form a connecting portion, and the connecting portion is connected to the tumor cavity coating segment.

7 . The coated stent according to claim 6 , wherein the connecting portion of the first coating is connected to the connecting portion of the second coating.

8. The coated stent according to claim 7, characterized in that the first coating and the second coating are integrally formed.

9. The coated stent according to claim 3 is characterized in that the first distal bevel and the second distal bevel both include a long-axis side wall and a short-axis side wall in the circumferential direction, the axial extension length of the long-axis side wall is greater than the axial extension length of the short-axis side wall, the long-axis side walls of the first embedded stent and the second embedded stent are arranged closely to each other, and a hooking portion for hooking is provided at the distal end of at least one of the long-axis side walls.

10. The coated stent according to claim 1, characterized in that the supporting wave ring includes at least one anchoring wave ring, and a plurality of anchoring barbs are provided on the outer side of the anchoring wave ring along the circumferential direction.

11. A stent delivery system, characterized in that it comprises the coated stent according to any one of claims 1-10.