CN119423853A - An integrated device for minimally invasive biopsy and anesthesia of abdominal wall fat tissue and its use method and application - Google Patents

Abstract

The present invention relates to an integrated anesthesia device for minimally invasive biopsy of abdominal wall fat tissue and its use method and application. The above device includes an integrated sterile needle for anesthesia injection and fat sampling, which includes a puncture needle, a needle connection part, a compressible cavity, and a pressing head connected in sequence. The pressing head has a connecting hole connected to the compressible cavity, and a detachable sealing member is arranged on the top of the connecting hole. The compressible cavity contains an anesthetic injection solution, and the bottom of the puncture needle is provided with a sealing cover sleeved on the outside of its opening; the above device also includes a surface anesthesia dressing, a micro negative pressure pump, tweezers, a sample dispensing tube, and a sterile cotton swab. The above device uses a surface anesthesia dressing, anesthesia injection and an integrated sterile needle for fat sampling in a matching manner, so that the preparation is simple and the steps of collecting fat tissue are simplified; the biopsy method involved adopts minimally invasive technology, which reduces tissue damage and postoperative recovery time; the above device can also be integrated into a reagent kit for direct detection of fat tissue.

Description

Abdominal wall adipose tissue minimally invasive biopsy anesthesia integrated device and use method and application thereof

Technical Field

The invention relates to the technical field of medical appliances, in particular to an integrated device for minimally invasive biopsy and anesthesia of abdominal wall adipose tissue, and a use method and application thereof.

Background

The tissue aspiration biopsy technique refers to pathological examination performed by taking part of living pathological tissues by using a hollow puncture needle, and is often used for diagnosing and evaluating body surface tumor, lymph node, thyroid, liver, lung, breast and kidney pathological changes. The puncture biopsy has the advantages of small damage, quick recovery and definite diagnosis. The puncture biopsy needle is a medical instrument for sampling and sucking cells from living tissues of cone tumors, unknown tumors and the like of various organs such as kidneys, livers, lungs, breasts, thyroid glands, prostates, pancreas, testes, uterus, ovaries, body surfaces and the like. Conventional biopsy needles have been used so far mainly for needle biopsies of breast, thyroid, muscle, lung and liver, but they are generally not suitable for adipose tissue, and the technique of needle biopsy of adipose tissue is rarely applied clinically to the work of diagnosis and treatment related to obesity.

Although there are also puncture needles capable of performing biopsy on adipose tissue in the prior art, for example, chinese patent CN115192090a discloses a biopsy device for single insertion of multiple samples, which includes a power-on driver assembly and a biopsy probe assembly (including a sample groove and a cutter sleeve) that can promote efficient cutting of a tissue sample and efficient transfer of the tissue sample to a sample collection container, chinese patent CN117838202a discloses an abdominal wall biopsy device that can dynamically adjust a negative pressure suction force of a syringe by a ratchet mechanism to achieve rapid extraction of adipose tissue to improve extraction efficiency, chinese patent CN213551989U discloses a novel adipose biopsy needle including a syringe, a push rod and a support column, wherein a space inside the syringe is divided into a front end for receiving adipose tissue and a rear end for movement of the push rod to solve problems of difficult extraction of the adipose sample in the conventional adipose biopsy needle, recovery is difficult and easy to be damaged, the support column can be abutted with a tail fin of the end of the push rod to ensure a negative pressure state inside the syringe, and related art discloses a syringe that can safely and effectively obtain a biopsy needle of about 10 mg of adipose tissue sample by using a syringe needle in a non-clinical environment to obtain a syringe of about 10 mg of biopsy needle, and a biopsy needle of about 200mg of tissue can be sucked into the syringe needle. However, the above-mentioned components and the operation method thereof still have the problems that 1) before the components are used, an operator is required to perform separate local anesthesia operation, so that the operation steps of fat biopsy are increased, and anesthetic drugs and syringes are also required to be prepared separately, 2) the operation process of sucking tissues by the components is still complicated, the steps are complex, 3) the local anesthesia before the fat biopsy step requires the operator to be a medical staff, and is familiar with the step of local anesthesia, and the puncturing process itself still has high requirements on clinical medical professions of the operator.

Disclosure of Invention

In order to overcome at least one problem in the prior art, the invention optimally designs the anesthesia injection and fat sampling integrated sterile needle, and prepares the anesthesia injection and fat sampling integrated sterile needle and other necessary components into an abdominal wall adipose tissue minimally invasive biopsy anesthesia integrated device, wherein the device is suitable for collecting adipose tissues and can be placed in a detection kit to be applied to the related field of obesity prevention and treatment, and the device adopts the integrated anesthesia biopsy needle, so that the operation steps are effectively simplified, the operation is convenient, and the technical requirements on operators are reduced to a certain extent.

In order to achieve the above purpose, the invention adopts the following technical scheme:

The invention provides an integrated device for minimally invasive biopsy and anesthesia of abdominal wall adipose tissue, which comprises an integrated sterile needle for anesthesia injection and fat sampling, wherein the integrated sterile needle for anesthesia injection and fat sampling comprises a puncture needle, a needle head connecting part, a compressible cavity and a pressing head which are sequentially connected, the pressing head is provided with a connecting hole communicated with the compressible cavity, the top of the connecting hole is provided with a detachable sealing piece, the compressible cavity contains anesthetic injection, and the bottom of the puncture needle is provided with a sealing cover sleeved outside an opening of the puncture needle.

In some embodiments, the compressible cavity is made of soft plastic, the hollow of the fluid in the compressible cavity can be realized in a compressed state, and the needle connecting part and the pressing head are made of hard plastic which is not easy to deform, so that the needle connecting part and the pressing head are respectively used for fixing the puncture needle and the compressible cavity.

In some of these embodiments, the top of the connection hole is flush with the top of the pressing head, and the inside of the connection hole is provided with threads. In some alternative embodiments, the top of the connecting hole protrudes from the top of the pressing head, and threads are arranged outside or inside the connecting hole.

In some of these embodiments, the seal is a sealing plug or sealing membrane.

In some embodiments, the bottom of the puncture needle is provided with a pore, and the outside of the pore is sleeved with a sealing ring.

In some of these embodiments, the outer portion of the needle attachment portion secures an auxiliary pressing portion.

In some of these embodiments, a plurality of bolus location icons, which are bolus depths of the puncture needle set according to the body shape of the patient, are marked at the middle-upper portion of the puncture needle.

In some of these embodiments, the device further comprises a topical anesthetic application.

In some embodiments, the superficial anesthetic application comprises an upper film layer, a middle medium layer and a lower film layer which are sequentially arranged, wherein the middle medium layer is anesthetic cream positioned at the central part and fixed at the bottom of the upper film layer, and the lower film layer is fixed with the bottom of the upper film layer through a glue paste.

In some embodiments, the upper film layer is a highly breathable sterile nonwoven, the intermediate medium layer is a sterile nonwoven cotton that adsorbs anesthetic cream, and the lower film layer is a plastic film.

In some of these embodiments, the device further comprises a miniature negative pressure pump.

In some embodiments, the miniature negative pressure pump is a medical rechargeable/battery type negative pressure suction motor head, which is provided with a suction nozzle and an exhaust nozzle, vacuum or negative pressure can be continuously formed at an inlet, micro positive pressure is formed at the exhaust nozzle, and the adjustment range of the miniature negative pressure pump is 0mmHg to-100 mmHg.

In some of these embodiments, the suction nozzle of the miniature negative pressure pump is connected to the connection hole by a screw thread so as to communicate with the compressible cavity. When the micro negative pressure pump is activated, a vacuum or negative pressure is created within the compressible cavity.

In some of these embodiments, the device further comprises forceps, sample dispensing vials, sterile swabs.

In some of these embodiments, the forceps are disposable sterile plastic forceps and the sterile cotton swab is an iodophor-containing sterile cotton swab.

A second aspect of the present invention provides a method for using the integrated device for minimally invasive biopsy and anesthesia of adipose tissue in the abdominal wall according to any one of the first aspect, comprising the steps of:

Step S1, sterilizing the skin surface of the puncture part by using a sterilizing cotton swab, wherein the sterilizing times are preferably 2 times.

And S2, tearing the lower film layer of the superficial anesthetic application, and correspondingly applying anesthetic cream in the superficial anesthetic application to the sterilized skin, wherein the application time is preferably at least 20 minutes.

S3, after the surface anesthesia is finished, removing a sealing cover at the bottom of the puncture needle after the positioning is determined again, and penetrating the sealing cover into the surface anesthesia application and the skin;

s4, after the local anesthesia is completed, removing a sealing piece at the top of a connecting hole in the pressing head, and communicating an air suction nozzle of the miniature negative pressure pump with the connecting hole;

s5, starting a miniature negative pressure pump, wherein subcutaneous adipose tissue can smoothly enter the emptied compressible cavity through the puncture needle;

and S6, after the adipose tissue collection is finished, slowly pulling out the puncture needle from the skin, and sub-packaging the obtained adipose tissue into sample sub-packaging small tubes by using forceps, wherein at the moment, the superficial anesthetic application is used as an adhesive bandage and is kept stuck to the puncture part of the skin.

The third aspect of the invention provides an application of the integrated device for minimally invasive biopsy and anesthesia of abdominal wall adipose tissue in the first aspect in preparing an adipose tissue detection kit.

In some of these embodiments, the kit is for detecting adipose tissue lipid metabolites or metabolic health related genes.

In some embodiments, the kit can be applied to screening of drugs in the field of obesity prevention and treatment, and the like.

Compared with the prior art, the invention has the following beneficial effects by adopting the technical scheme:

The invention develops a minimally invasive biopsy anesthesia integrated device for pressing and sucking abdominal wall adipose tissue for adipose tissue biopsy, wherein a biopsy needle is specially designed for the abdominal wall adipose tissue, so that safe and accurate adipose tissue collection is allowed under local anesthesia, and the biopsy needle reduces the postoperative recovery time and the risk of complications through a minimally invasive technology, and can allow a doctor to quickly perform in an outpatient environment.

The integrated device for minimally invasive biopsy and anesthesia of the abdominal wall has the advantages that (1) the integrated device for minimally invasive biopsy and anesthesia of the abdominal wall is designed for surface anesthesia, local anesthesia and fat biopsy puncture, the integrated sterile needle for surface anesthesia application, anesthesia injection and fat sampling is matched with the integrated sterile needle for use, conventional anesthesia products such as medicines and syringes prepared in the whole process of puncture are reduced, disinfection and anesthesia steps before puncture and binding steps after puncture are simplified, (2) the integrated sterile needle for anesthesia injection and fat sampling is easy and convenient to operate, operators do not need to master local anesthesia skills, even non-medical professionals can operate, 3) the steps for collecting fat tissue are simplified, the preparation is simple, the integrated device is convenient to use in clinic and non-complex medical environments, no other objects are needed, the biopsy method of the integrated device for minimally invasive biopsy is used for reducing tissue damage and postoperative recovery time, accurate matched sampling is guaranteed, and the integrated device for obtaining sufficient and quality fat tissue samples has wide application potential and can be widely applied to conventional clinical diagnosis and prevention and treatment.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and do not constitute a limitation on the invention. In the drawings:

FIG. 1 is a schematic view of an integrated anesthesia injection and fat sampling sterile needle in accordance with one embodiment of the present invention;

FIG. 2 is a schematic cross-sectional view of the anesthesia injection and fat sampling integrated sterile needle shown in FIG. 1;

FIG. 3 is a schematic illustration of a superficial anesthetic application in accordance with an embodiment of the present invention;

FIG. 4 is a schematic cross-sectional view of the topical anesthetic application shown in FIG. 3;

FIG. 5 is a schematic view showing the operation steps of the integrated device for minimally invasive biopsy and anesthesia of adipose tissue in the abdominal wall according to an embodiment of the present invention;

FIG. 6 is an optimized view of a puncture needle according to an embodiment of the present invention;

FIG. 7 is an optimized view of a needle attachment portion according to one embodiment of the present invention;

The reference numerals of the device are 1-anesthesia injection and fat sampling integrated sterile needle, 11-compressible cavity, 111-anesthesia injection, 12-pressing head, 13-connecting hole, 14-sealing piece, 15-needle connecting part, 151-auxiliary pressing part, 16-puncture needle, 161-pore, 162-sealing ring, 17-sealing cover, 2-surface anesthesia application, 21-lower film layer, 22-middle medium layer, 23-upper film layer, 3-skin, 4-miniature negative pressure pump, 5-forceps, 6-sample split charging small tube, 7-disinfection cotton swab and 8-fat tissue.

Detailed Description

The present application will be described and illustrated with reference to the accompanying drawings and examples in order to make the objects, technical solutions and advantages of the present application more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the application. All other embodiments, which can be made by a person of ordinary skill in the art based on the embodiments provided by the present application without making any inventive effort, are intended to fall within the scope of the present application.

It is apparent that the drawings in the following description are only some examples or embodiments of the present application, and it is possible for those of ordinary skill in the art to apply the present application to other similar situations according to these drawings without inventive effort. Moreover, it should be appreciated that while such a development effort might be complex and lengthy, it would nevertheless be a routine undertaking of design, fabrication, or manufacture for those of ordinary skill having the benefit of this disclosure, and thus should not be construed as having the benefit of this disclosure.

Reference in the specification to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is to be expressly and implicitly understood by those of ordinary skill in the art that the described embodiments of the application can be combined with other embodiments without conflict.

Unless defined otherwise, technical or scientific terms used herein should be given the ordinary meaning as understood by one of ordinary skill in the art to which this application belongs. The terms "a," "an," "the," and similar referents in the context of the application are not to be construed as limiting the quantity, but rather as singular or plural. The terms "comprises," "comprising," "includes," "including," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or modules (elements) is not limited to only those steps or elements but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus. The terms "connected," "coupled," and the like in connection with the present application are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. The term "plurality" as used herein means two or more. "and/or" describes the association relationship of the association object, and indicates that three relationships may exist, for example, "a and/or B" may indicate that a exists alone, a and B exist simultaneously, and B exists alone. The character "/" generally indicates that the context-dependent object is an "or" relationship. The terms "first," "second," "third," and the like, as used herein, are merely distinguishing between similar objects and not representing a particular ordering of objects.

It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other. The invention is further described below with reference to the drawings and specific examples, which are not intended to be limiting.

EXAMPLE 1 anesthesia injection and fat sampling Integrated sterile needle

This embodiment is one illustrative embodiment of an anesthesia injection and fat sampling integrated sterile needle.

As shown in fig. 1 and 2, the above-mentioned components of the anesthesia injection and fat sampling integrated sterile needle 1 are generally biased to be cylindrical with hollow interior, and include a puncture needle 16, a needle connecting portion 15, a compressible cavity 11 (the exterior of which is similar to a plurality of rings, the interior of which is hollow and has good compressibility), and a pressing head 12, which are sequentially connected, wherein the compressible cavity 11 is made of soft plastic, which can realize the evacuation of the liquid in the interior in a compressed state, the needle connecting portion 15 and the pressing head 12 are made of hard plastic which is not easy to deform, so as to be used for fixing the puncture needle 16 and the compressible cavity 11, and the needle connecting portion 15, the compressible cavity 11 and the pressing head 12 are integrally formed components, and the materials of the compressible cavity 11 and the pressing head 12 are all conventional materials in the art. The central bottom of the needle attachment 15 is attached to the top of the needle 16 in a manner that is conventional in the art with reference to syringes. The bottom of the needle 16 is in the shape of a conventional pointed needle with an opening to facilitate rapid penetration of the needle.

As shown in fig. 2, a connecting hole 13 communicating with the compressible cavity 11 is formed in the central portion of the pressing head 12, a detachable sealing member 14 (specifically, a rubber sealing plug, a sealing sheet made of aluminum foil, or a sealing film made of plastic) is disposed at the top of the connecting hole 13, the compressible cavity 11 contains a predetermined amount of anesthetic 111 (for local anesthesia) in an initial state, and a sealing cover 17 sleeved outside the opening of the puncture needle 16 is disposed at the bottom of the puncture needle 16 for sealing the opening at the bottom of the puncture person to prevent leakage of the anesthetic 111 in the compressible cavity 11 in the initial state.

In some alternative embodiments, as shown in fig. 6, a hole 161 is formed at the bottom of the puncture needle 16, a sealing ring 162 is sleeved outside the hole 161, and at this time, an opening is formed at the bottom of the puncture needle 16 or not, and the cooperation between the hole 161 and the opening at the bottom can enable the anesthetic injection to be infiltrated into the tissues around the puncture site at different positions at multiple points, which is more beneficial to local anesthesia.

As shown in fig. 2, the top of the connecting hole 13 located at the center of the pressing head 12 is flush with the top of the pressing head 12, i.e., the connecting hole 13 is directly connected to the inner space of the compressible chamber 11 through the pressing head 12, and at this time, threads are provided inside the connecting hole 13 for connection with a negative pressure device.

In some alternative embodiments, as shown in fig. 7, the top of the connecting hole 13 protrudes from the top of the pressing head 12, that is, the connecting hole 13 is a circular hole channel extending through the pressing head 12 and extending outward, and the outside or inside of the connecting hole 13 is provided with threads, which increases the convenience of operation when connecting an external negative pressure device.

In some alternative embodiments, as shown in fig. 7, an auxiliary pressing portion 151 (which may be a ring fixed to the periphery of the needle connecting portion 16, or may be 2 pressing pieces fixed to the needle connecting portion 16 and symmetrically distributed) is fixed to the outside of the needle connecting portion 16, so that the puncture needle can be first inserted into the skin during operation, and then anesthetic injection is performed, which is advantageous for injecting the anesthetic at a uniform speed.

In some alternative embodiments, a plurality of bolus location icons (not shown) are marked on the upper portion of the puncture needle 16, which are bolus depths of the puncture needle set according to the body type of the patient, for example, a patient with a weak body shape, a patient with a shallow bolus depth, a patient with a fat body shape, and a bolus depth, and the bolus location icons may take the form of a conventional scale.

The anesthesia injection and fat sampling integrated sterile needle built-in anesthesia injection does not need to prepare an anesthetic and an injector separately, simplifies local anesthesia operation, is simple and convenient to operate, does not need an operator to master local anesthesia skills, and can be operated even by non-medical professionals.

Example 2-Abdominal wall adipose tissue minimally invasive biopsy anesthesia Integrated device

This embodiment is an exemplary embodiment of a preferred integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device comprising the anesthesia injection and fat sampling integrated sterile needle described in embodiment 1. As shown in fig. 5, the integrated device for minimally invasive biopsy and anesthesia of abdominal wall adipose tissue comprises an anesthesia injection and fat sampling integrated sterile needle 1, a superficial anesthesia application 2, a miniature negative pressure pump 4, forceps 5, a sample split charging small tube 6 and a disinfection cotton swab 7, wherein the number of the accessories can be 1 or more. The anesthesia injection and fat sampling integrated sterile needle 1 is used for achieving local anesthesia and fat tissue acquisition, a disinfection cotton swab 7 (which can be a disinfection cotton swab with an iodophor) is used for disinfecting a puncture part, the surface anesthesia application 2 is used for achieving positioning and surface anesthesia of the puncture part, the miniature negative pressure pump 4 is matched with the anesthesia injection and fat sampling integrated sterile needle 1 to enable the inside of the compressible cavity 11 to be in a negative pressure state, and the forceps 5 (which can be disposable sterile plastic forceps) are used for taking out the fat tissue in the compressible cavity 11 and sub-packaging the fat tissue into the sample sub-packaging small tube 6.

As shown in fig. 3 and 4, the superficial anesthetic plaster 2 includes an upper film layer 23, an intermediate medium layer 22, and a lower film layer 21 sequentially arranged, wherein the intermediate medium layer 22 is anesthetic cream fixed to the bottom of the upper film layer 23 at the central portion, and the lower film layer 21 is fixed to the bottom of the upper film layer 23 by a glue. The overall shape of the superficial anesthetic application 2 may be a strip shape, the anesthetic cream is a disc shape or a strip shape, the structural form of the superficial anesthetic application 2 is similar to that of a band-aid conventionally used in the art, for example, the upper film layer 23 is a sterile non-woven fabric with high air permeability, the middle medium layer 22 is a sterile non-woven cotton for adsorbing medicines, the lower film layer 21 is a plastic film, and only medicines in the band-aid are replaced by anesthetic cream.

As shown in fig. 5, the micro negative pressure pump 4 is provided with a suction nozzle and a discharge nozzle, vacuum or negative pressure can be continuously formed at an inlet, micro positive pressure is formed at the discharge nozzle, and the suction nozzle of the micro negative pressure pump 4 is connected with the connecting hole 13 through threads so as to be communicated with the compressible cavity 11. When the micro negative pressure pump 4 is started, vacuum or negative pressure is formed inside the compressible cavity 11, so that adipose tissues are obtained, and the micro negative pressure pump 4 can be a medical rechargeable/battery type negative pressure suction motor head which is conventionally used.

The integrated device for minimally invasive biopsy and anesthesia of the abdominal wall adipose tissue integrates surface anesthesia, local anesthesia and fat biopsy puncture, reduces conventional anesthesia products such as medicines and syringes prepared in the whole puncture process, simplifies sterilization and anesthesia steps before puncture and bandaging steps after puncture, does not need any other articles when collecting adipose tissue, can be integrated into a detection kit, and can directly detect the content of lipid metabolites of the adipose tissue or the expression of metabolic health related genes after pretreatment of the collected adipose tissue, thereby being beneficial to determining the treatment scheme for preventing and treating obesity.

Example 3-use of Integrated device for minimally invasive biopsy and anesthesia of Abdominal adipose tissue

This embodiment is an exemplary embodiment of an operation method of the integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device according to embodiment 2, and as shown in fig. 5, the operation method of the device specifically includes the steps of:

step S1, sterilizing the surface of the skin 3 at the puncture part twice by using a sterilizing cotton swab 7;

Step S2, tearing the lower film layer 21 of the superficial anesthetic application 2, correspondingly applying anesthetic cream in the center of the superficial anesthetic application 2 to the sterilized skin 3, and carrying out surface local anesthetic puncture for at least 20 minutes;

and S3, after the surface anesthesia is finished, the positioning is determined again, and then the sealing cover 17 at the bottom of the puncture needle 16 is removed to be penetrated into the superficial anesthesia application 2 and the skin 3, wherein in the puncture process, the anesthetic injection 111 in the compressible cavity 11 can smoothly infiltrate into tissues around the puncture point from all layers through the bottom opening of the puncture needle 16 for local anesthesia.

The specific operation of the above step S3 is to slowly push the pressing head 12 with the thumb so that the puncture needle 16 is introduced into the patient' S skin. The subcutaneous fat level of the patient is estimated according to the body type of the patient, and the pressing head 12 is injected to the estimated position. If this step involves the components of fig. 6 and 7, the operation step may be adjusted such that the puncture needle 16 is first pushed slowly into the estimated skin position by the thumb pressing the auxiliary pressing portion 151, and then the pressing head 12 is pushed slowly by the thumb, and if the puncture needle 16 is provided with the fine hole 161 and the seal ring 162, the seal ring 162 moves upward with the puncture needle 16 to expose the fine hole 161.

S4, after the local anesthesia is completed, removing a sealing piece 14 at the top of a connecting hole 13 in the pressing head 12, and communicating the suction nozzle of the miniature negative pressure pump 4 with the connecting hole 13 through threads in a rotating way, so that the communication with the compressible cavity 11 is realized;

S5, starting a miniature negative pressure pump 4 (the adjusting range is 0mmHg to 100 mmHg), and enabling subcutaneous adipose tissue 8 to smoothly enter an emptied compressible cavity 11 through a puncture needle 16 (the anesthetic injection and the adipose tissue adopt the same container and cannot pollute the adipose tissue, because the anesthetic injection and the container are sterile, and secondly, extremely little anesthetic residual components cannot interfere with the follow-up detection result of the adipose tissue);

And S6, after the collection of the adipose tissues 8 is finished, slowly pulling out the puncture needle 16 from the skin, sub-packaging the obtained adipose tissues 8 into sample sub-packaging small tubes 6 by using forceps 5, and preparing for inspection after marking, wherein at the moment, the superficial anesthetic application 2 is used as a band-aid and is kept stuck to the puncture part of the skin 3.

The integrated device for minimally invasive biopsy and anesthesia of the abdominal wall adipose tissue is simple to use and convenient to operate, and effectively reduces the technical requirements on operators, so that the integrated device has wide application potential.

As can be seen from the above embodiments, the present invention has developed a minimally invasive biopsy anesthesia integrated device for pressing and sucking adipose tissue in the abdominal wall, which adopts a biopsy needle to reduce conventional anesthesia products such as medicines and syringes prepared during the whole puncturing process, and to simplify sterilization and anesthesia steps before puncturing and bandaging steps after puncturing, which does not require operators to grasp local anesthesia skills, can be operated even by non-medical professionals, and can safely and effectively acquire samples from adipose tissue for diagnosis and treatment related to obesity, and which can reduce invasive and postoperative complications, provide accurate sampling, and allow for performing under outpatient conditions, so that the integrated anesthesia biopsy needle is more suitable for frequent clinical examinations.

The above description of the specific embodiments of the present invention has been given by way of example only, and the present invention is not limited to the above described specific embodiments. Any equivalent modifications and substitutions for the present invention will occur to those skilled in the art, and are also within the scope of the present invention. Accordingly, equivalent changes and modifications are intended to be included within the scope of the present invention without departing from the spirit and scope thereof.

Claims (10)

1. The utility model provides an integrative device of abdominal wall adipose tissue wicresoft biopsy anesthesia, its characterized in that, the device includes anesthesia injection and fat sampling integral type aseptic needle, anesthesia injection and fat sampling integral type aseptic needle is including pjncture needle, syringe needle connecting portion, compressible cavity, the pressing head that connects gradually, the pressing head set up one with the connecting hole of compressible cavity intercommunication, the top of connecting hole sets up detachable sealing member, contain anesthesia injection in the compressible cavity, the sealed lid of its opening outside is located to the bottom setting cover of pjncture needle.

2. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device according to claim 1, wherein the compressible cavity is made of soft plastic, which can realize evacuation of liquid in the compressible cavity, and the needle connecting portion and the pressing head are made of hard plastic which is not easy to deform, so as to be used for fixing the puncture needle and the compressible cavity respectively.

3. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of claim 1, wherein the top of the connection hole is flush with the top of the pressing head, and the inside of the connection hole is provided with threads.

4. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of claim 1, further comprising a superficial anesthesia application.

5. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of claim 4, wherein the superficial anesthesia application comprises an upper thin film layer, an intermediate medium layer and a lower thin film layer which are sequentially arranged, wherein the intermediate medium layer is anesthetic cream fixed at the bottom of the upper thin film layer at the central part, and the lower thin film layer is fixed with the bottom of the upper thin film layer through a glue.

6. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of any one of claims 1-5, further comprising a miniature negative pressure pump.

7. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of claim 6, wherein the suction nozzle of the miniature negative pressure pump is threadably connected to the connection aperture such that it is in communication with the compressible cavity.

8. The integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of claim 6 further comprising forceps, sample dispensing vials, sterile swabs.

9. A method of using the integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device of any one of claims 1-8, comprising the steps of:

Step S1, disinfecting the skin surface of the puncture part by using a disinfecting cotton swab;

s2, tearing a lower film layer of the surface anesthesia application, and correspondingly applying the anesthesia cream in the surface anesthesia application to the sterilized skin;

S3, after the surface anesthesia is finished, removing a sealing cover at the bottom of the puncture needle after the positioning is determined again, and penetrating the sealing cover into the surface anesthesia application and the skin;

s4, after the local anesthesia is completed, removing a sealing piece at the top of a connecting hole in the pressing head, and communicating an air suction nozzle of the miniature negative pressure pump with the connecting hole;

s5, starting a miniature negative pressure pump, wherein subcutaneous adipose tissue can smoothly enter the emptied compressible cavity through the puncture needle;

and S6, after the adipose tissue collection is finished, slowly pulling out the puncture needle from the skin, and sub-packaging the obtained adipose tissue into sample sub-packaging small tubes by using forceps, wherein at the moment, the superficial anesthetic application is used as an adhesive bandage and is kept stuck to the puncture part of the skin.

10. Use of the integrated abdominal wall adipose tissue minimally invasive biopsy anesthesia device according to any one of claims 1-8 in the preparation of an adipose tissue detection kit.