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CN119410416A - A kind of hand cleaning liquid and its preparation method and application - Google Patents

A kind of hand cleaning liquid and its preparation method and application Download PDF

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Publication number
CN119410416A
CN119410416A CN202411446034.3A CN202411446034A CN119410416A CN 119410416 A CN119410416 A CN 119410416A CN 202411446034 A CN202411446034 A CN 202411446034A CN 119410416 A CN119410416 A CN 119410416A
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China
Prior art keywords
hand
detergent
surfactant
protecting
examples
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CN202411446034.3A
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Inventor
骆建华
龙倩滢
廖宇
吴鹰花
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Zhongshan Lanju Daily Chemical Industries Co Ltd
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Zhongshan Lanju Daily Chemical Industries Co Ltd
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Priority to CN202411446034.3A priority Critical patent/CN119410416A/en
Publication of CN119410416A publication Critical patent/CN119410416A/en
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    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88Ampholytes; Electroneutral compounds
    • C11D1/94Mixtures with anionic, cationic or non-ionic compounds
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02Anionic compounds
    • C11D1/37Mixtures of compounds all of which are anionic
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/20Organic compounds containing oxygen
    • C11D3/2068Ethers
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/20Organic compounds containing oxygen
    • C11D3/2075Carboxylic acids-salts thereof
    • C11D3/2086Hydroxy carboxylic acids-salts thereof
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/26Organic compounds containing nitrogen
    • C11D3/33Amino carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/34Organic compounds containing sulfur
    • C11D3/349Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/382Vegetable products, e.g. soya meal, wood flour, sawdust
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02Anionic compounds
    • C11D1/12Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/22Sulfonic acids or sulfuric acid esters; Salts thereof derived from aromatic compounds
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02Anionic compounds
    • C11D1/12Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/28Sulfonation products derived from fatty acids or their derivatives, e.g. esters, amides
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02Anionic compounds
    • C11D1/12Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/29Sulfates of polyoxyalkylene ethers
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88Ampholytes; Electroneutral compounds
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88Ampholytes; Electroneutral compounds
    • C11D1/90Betaines

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)

Abstract

本发明公开了一种护手洗洁精及其制备方法与应用,护手洗洁精的组份包括:脂肪酸甲酯磺酸钠、直链烷基苯磺酸钠和脂肪醇聚氧乙烯醚硫酸钠。本发明的护手洗洁精的配方体系呈现低刺激的状态,在保证洗洁精的去污功效同时达到护手的效果。The present invention discloses a hand-protecting detergent and a preparation method and application thereof. The components of the hand-protecting detergent include sodium fatty acid methyl ester sulfonate, sodium linear alkyl benzene sulfonate and sodium fatty alcohol polyoxyethylene ether sulfate. The formula system of the hand-protecting detergent of the present invention is low-irritating, and the hand-protecting effect is achieved while ensuring the decontamination effect of the detergent.

Description

Hand-protecting detergent and preparation method and application thereof
Technical Field
The invention relates to the technical field of daily chemical products, in particular to a hand-protecting detergent and a preparation method and application thereof.
Background
The detergent is used as a very common washing article in family life and is a product for cleaning dirt and greasy dirt commonly used in families. Since the detergent is in close contact with food and human skin, it is required to be as gentle as possible to human skin, and also to have a good detergency. The main components of the prior detergent are surfactants, the components such as the surfactants and the preservatives used by the prior detergent are generally synthetic chemicals, the surfactant has the advantages of strong detergency, good solubility and lower cost, but if the detergent is used for a long time, the trace detergent components remained on tableware can generate potential threat to human bodies, and can negatively affect the skin of the detergent user, so that the skin is easy to turn yellow, especially the skin is more sensitive to the user, the symptoms such as dryness, peeling, roughness and easy foaming of hands can occur when the detergent is used for a long time, and the detergent sold at present mostly adopts the chemical surfactants such as sodium dodecyl benzene sulfonate, fatty alcohol polyoxyethylene ether sulfate and the like as the main cleaning components, and the detergent is ideal in washing detergency and easy to cause harm to the skin of people when the detergent is used for a long time.
Therefore, it is urgent to develop a cleanser which has low irritation to human skin.
Disclosure of Invention
The present invention aims to solve the above-mentioned technical problems existing in the prior art. Therefore, the invention provides the hand-protecting detergent and the preparation method and the application thereof, wherein the formula system of the detergent presents a low-irritation state, and the effect of protecting the hands is achieved while the decontamination effect of the detergent is ensured.
The invention also provides a preparation method of the hand-protecting detergent.
The invention also provides application of the detergent in the field of daily chemical products.
According to one aspect of the invention, a hand-protecting detergent is provided, and the hand-protecting detergent comprises sodium fatty acid methyl sulfonate, sodium linear alkylbenzene sulfonate and sodium fatty alcohol polyoxyethylene ether sulfate.
According to an embodiment of the first aspect of the invention, at least the following advantages are achieved:
When fatty acid methyl sodium sulfonate (MES) is compounded with Linear Alkylbenzene Sulfonate (LAS) and fatty alcohol polyoxyethylene ether sodium sulfate (AES), the MES can obviously reduce the irritation of LAS and AES, the system is low in irritation, and meanwhile, the detergency of a formula in compounding the MES, the AES and the LAS is better in improving effect. Fatty acid Methyl Ester Sulfonate (MES), also known as alpha-sulfo fatty acid methyl ester salt, has excellent calcium soap dispersing ability, low irritation and good biodegradability. The fatty acid methyl ester part in MES has similar structure and similar property to the fatty acid glyceride in skin, and has better compatibility with skin. When MES contacts skin, it forms an oil film on the skin surface to reduce water loss. Thus, MES is gentle to the skin.
In some embodiments of the invention, the hand lotion comprises, by weight, 7.2-27:0.3-5:2-12.85 of fatty acid methyl ester sodium sulfonate, straight-chain sodium alkylbenzene sulfonate and fatty alcohol polyoxyethylene ether sodium sulfate.
After the functional surfactant is compounded in the formula of MES, LAS and AES in the proportion, the irritation of the system can be obviously reduced, and the detergency can be improved.
In some embodiments of the present invention, the hand cleanser further comprises a copolymer of an acrylic polymer grafted polyether compound.
In some embodiments of the invention, the copolymer of the acrylic polymer grafted polyether compound comprises the structure of formula I or formula II:
R 1 is selected from one of the following structures:
Wherein a is 0 to 25, b is 0 to 8, z is 0 to 25, y (x+z) is 0.1 to 0.4, n is a positive integer of 2 to 14, and m is a positive integer of 2 to 12.
The functional surfactant is a copolymer of acrylic polymer grafted polyether compound, is a novel functional polymer material, and has excellent water absorption and colloid property. The action mechanism is that hydrophilic groups of the functional surfactant are crosslinked with surfactant components in the system to form a three-dimensional structure, so that the resistance of the components in water is increased, the van der Waals force among particles is increased, the distance among the particles is reduced, the viscosity of the system is increased, and the thickening effect is achieved. In addition, when the system is contacted with skin, the functional surfactant can cooperate with fatty acid methyl ester sulfonate, and the lipophilic group of the functional surfactant assists the fatty acid methyl ester portion of the fatty acid methyl ester sulfonate to form an oil film on the surface of the skin, so that the water loss of the skin is reduced. Meanwhile, hydrophilic groups of the functional surfactant can form hydrogen bonds with water molecules around the skin to adsorb moisture on the surface of the skin, so that a layer of protective film is formed, loss of skin moisture is further reduced, moisture is locked, and the skin is helped to keep moist and soft.
In some embodiments of the invention, the hand lotion comprises, by weight, 5-30 parts of fatty acid methyl ester sodium sulfonate, 0.3-10 parts of linear alkylbenzene sodium sulfonate and 2-15 parts of fatty alcohol polyoxyethylene ether sodium sulfate.
After the MES, LAS and AES are compounded in the weight parts, the functional surfactant further reduces the irritation of the system and remarkably improves the skin feel after washing.
In some embodiments of the present invention, the hand cleanser further comprises an amphoteric surfactant comprising at least one of an amino acid surfactant, a betaine surfactant, an imidazoline surfactant, and an amine oxide surfactant.
In some embodiments of the invention, the amphoteric surfactant is cocamidopropyl betaine.
In some embodiments of the present invention, the hand cleanser further comprises an adjunct comprising a chelant, a fragrance, a preservative, and an inorganic salt.
According to the invention, the hand-protecting detergent comprises, by weight, 5-30 parts of fatty acid methyl ester sodium sulfonate, 0.3-5 parts of linear alkylbenzene sodium sulfonate, 2-15 parts of fatty alcohol polyoxyethylene ether sodium sulfate, 0-2 parts of functional surfactant, 0-5 parts of amphoteric surfactant, 0-0.5 part of chelating agent, 0-0.5 part of essence, 0-1 part of preservative and 0-1.5 part of inorganic salt.
The invention controls the compounding proportion of Linear Alkylbenzene Sulfonate (LAS), fatty alcohol polyoxyethylene ether sodium sulfate (AES), fatty acid methyl ester sodium sulfonate (MES), copolymer of acrylic polymer grafted polyether compound and other components, and the obtained composition can keep uniform and transparent at low temperature and has low manufacturing cost. The irritation is low, far lower than that of the traditional detergent sold in the market, the decontamination performance is higher than that of the national standard tableware detergent and is not inferior to that of the traditional tableware detergent sold in the market, and meanwhile, the detergent has the feasibility of mass production.
In some embodiments of the invention, the hand cleanser further comprises water.
In some embodiments of the invention, the chelating agent comprises at least one of ethylenediamine tetraacetate, diethylenetriamine pentaacetate, methylglycine diacetate, glutamic acid diacetate, and sodium citrate dihydrate.
In some embodiments of the invention, the chelator comprises glutamate diacetate.
In some embodiments of the invention, the essence comprises herbal, fruit, flower.
In some embodiments of the invention, the herbal flavoring agents include peppermint, spearmint, rosemary, thyme, sage, pine and spruce.
In some embodiments of the invention, the fruit flavor comprises apple, almond, grape, cherry, pineapple, pear, juicy peach, mango, orange, strawberry, blueberry, and citrus.
In some embodiments of the invention, the floral scent comprises rose, lavender, carnation, vanilla, gardenia, hawthorn, marjoram, honeysuckle, cyclamen, hyacinth, fern, clove, jasmine, lily, mimosa, magnolia, orchid, narcissus, orange, licorice, luteolin, clover, violet, sweet pea, and cinquefoil.
In some embodiments of the invention, the preservative comprises at least one of methylisothiazolinone, phenoxyethanol, and methylchloroisothiazolinone.
In some embodiments of the invention, the inorganic salt comprises at least one of a sodium salt and a magnesium salt.
In some embodiments of the invention, the sodium salt comprises sodium chloride.
In a second aspect of the invention, a method for preparing the hand lotion is provided, comprising the steps of mixing the components of the hand lotion.
In a third aspect of the invention, the application of the hand-protecting detergent in the field of daily chemicals is provided.
Drawings
FIG. 1 is a stimulus test chart of example 1 of the present invention;
FIG. 2 is a stimulus test chart of example 2 of the present invention;
FIG. 3 is a stimulus test chart of example 3 of the present invention;
FIG. 4 is a stimulus test chart of example 4 of the present invention;
FIG. 5 is a stimulus test chart of example 5 of the present invention;
FIG. 6 is a stimulus test chart of example 6 of the present invention;
FIG. 7 is a stimulus test chart of comparative example 1 of the present invention;
FIG. 8 is a stimulus test chart of comparative example 2 of the present invention;
FIG. 9 is a stimulus test chart of comparative example 3 of the present invention;
FIG. 10 is a stimulus test chart of comparative example 4 of the present invention;
FIG. 11 is a stimulus test chart of comparative example 5 of the present invention;
FIG. 12 is a graph of irritation test for a commercially available detergent.
Detailed Description
The conception and the technical effects produced by the present invention will be clearly and completely described in conjunction with the embodiments below to fully understand the objects, features and effects of the present invention. It is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments, and that other embodiments obtained by those skilled in the art without inventive effort are within the scope of the present invention based on the embodiments of the present invention.
Example 1
The embodiment provides a hand-protecting detergent and a preparation method thereof, wherein the weight percentage of each component of the hand-protecting detergent is shown in table 1.
The preparation method of the hand lotion in the embodiment 1 comprises the following steps:
S1, adding deionized water, a chelating agent and liquid alkali into a main reaction kettle, starting stirring, adding sodium alkylbenzenesulfonate, stirring, fully neutralizing, and controlling the pH value of the solution to be weak alkali;
S2, sequentially adding fatty acid methyl ester sodium sulfonate, fatty alcohol polyoxyethylene ether sodium sulfate, brine and the rest deionized water into the main reaction kettle, and stirring until the raw materials are completely dissolved to obtain a mixed solution;
S3, adding a pH regulator into the obtained mixed solution, controlling the pH value to be neutral, then sequentially adding a preservative and essence, and stirring until the raw materials are completely dissolved.
Examples 2 to 6
Examples 2-6 provide a hand cleanser and a preparation method thereof, wherein the weight percentage of each component of the hand cleanser is shown in table 1, and the preparation method is the same as that of example 1;
AG-U30 in examples 5 and 6 was a copolymer of an acrylic polymer-grafted polyether compound, purchased from green extract source biotechnology Co., ltd. In Buddha, and added in step S2.
Comparative example 1
Comparative example 1 provides a hand cleanser and a preparation method thereof, wherein the weight percentage of each component of the hand cleanser is shown in table 1, and the preparation method is the same as that of example 1.
Comparative example 2
Comparative example 2 provides a hand cleanser and a preparation method thereof, wherein the weight percentage of each component of the hand cleanser is shown in table 1, and the preparation method is the same as that of example 1.
Comparative example 3
Comparative example 3 provides a hand cleanser and a preparation method thereof, wherein the weight percentage of each component of the hand cleanser is shown in table 1, and the preparation method is the same as that of example 1.
Comparative example 4
Comparative example 4 provides a hand cleanser and a method of preparing the same, wherein the weight percentages of the components of the hand cleanser are shown in table 1, and the method of preparing the same is the same as that of example 1.
Comparative example 5
Comparative example 5 provides a hand cleanser and a method of preparing the same, wherein the weight percentages of the components of the hand cleanser are shown in table 1, and the method of preparing the same is the same as that of example 1.
Table 1 hand care detergent composition embodiments
Test example 1
The hand cleanser compositions of the above examples and comparative examples were subjected to performance test, and the results are shown in tables 2, 3 and fig. 1 to 12. The results of the irritation are shown in Table 4, and the specific operation method for evaluating the relevant test is as follows:
1) Irritation test
Chick embryo chorioallantoic membrane test several SPF chick embryos hatched to nine days old were taken, each 6 chick embryos were grouped, and each sample was tested in a corresponding group. Diluting the sample to 0.5% concentration with distilled water, dripping 0.3ml of test sample on the surface of chick embryo CAM film, observing CAM reaction condition, recording time of each toxic effect in 5min, and photographing and preserving test result state.
The stimulation scores were calculated using the following formula, with the results remaining two bits after the decimal point:
IS=(301-sec H)*5/300+(301-sec L)*7/300+(301-sec C)*9/300;
sec H (bleeding time) - - - -the average time in seconds(s) at which bleeding is observed on the CAM membrane;
sec L (vascular thawing time VESSEL LYSIS TIME) - - - -the average time in seconds(s) over which onset of vascular thawing is observed on the CAM membrane;
sec C (clotting time coagulation time) - - - -the average time in seconds(s) over which clotting is observed to begin on the CAM film;
table 2 hand care cleanser examples irritation results
TABLE 3 irritation results for commercially available liquid detergents
TABLE 4 evaluation of irritation results
Endpoint scoring Irritation classification
IS<1 No irritation
1≤IS<5 Light irritation
5≤IS<9 Mid-irritation
IS≥10 Strong irritation
From the results of the examples and comparative examples in Table 2, it can be seen that the results of the examples are lower than those of the comparative examples, the examples are in a light irritation range, and the examples are viable.
As can be seen from the results in Table 3 and Table 2, the commercially available detergents claiming hand protection efficacy were all strongly irritating, with irritation scores greater than 10, while the examples were all low irritating, mild to the skin, and practical examples were viable.
The formula of the embodiment is mild, compared with the comparative example 1, the embodiment can obviously reduce the irritation of LAS and AES by compounding MES, and obviously improve the irritation of a system.
As can be seen from the irritation results of examples 1-3, as the MES content decreases and the AES content increases, the irritation of the system increases slightly, but the range of light irritation is maintained. It can be obtained that when MES of the formula is in a certain proportion, the product has better stabilizing effect on the irritation of the system.
As can be seen from a comparison of the irritation results of examples and comparative examples 4,5, MES, AES, LAS maintain the irritation of the system within the range of light irritation when it is desired to compound within the proportions specified in the present invention. When the ratio is not in the specified ratio, the irritation of the system is obviously increased, at the moment, the amphoteric surfactant and AG-U30 are added, the irritation is not obviously changed, and the system is in a medium-irritation or near-strong-irritation state. MES, AES, LAS can be obtained, and the effect of light stimulation can be maintained by compounding the three components in the proportion specified by the invention.
The examples compare the irritation properties of comparative examples 2, 3. It can be obtained that MES, AES, LAS, when compounded in the specified proportion of the invention, is assisted with the functional surfactant AG-U30, and the irritation of the system can be lower than that of a formula system added with the special auxiliary agent of nonionic surfactant, fat-rich agent and humectant. The embodiment has obvious economic advantages compared with comparative examples 2 and 3, the common surfactant LAS, AES and the green anionic surfactant MES are compounded or the functional surfactant AG-U30 is added, and compared with a formula system of special auxiliary agents added with various lipid-rich agents and humectants, the formula is economic, the cost performance is higher, the production process is simple, and the feasibility is higher.
As can be seen from examples 4,5,6 and comparative example 4, the irritation of the system decreases as AG-U30 is compounded in the system, and decreases as the AG-U30 content increases.
Test example 2
The detergency was evaluated in this test example using the A.2 foam-site method of GB 9985 2022 hand dishwashing detergent appendix A detergency test, the results of which are shown in tables 5, 6:
Table 5 detergency results for hand care detergent examples
TABLE 6 detergency results for commercially available detergents
From the results of Table 5, it can be seen that the detergency of the examples all reached the standard, and the detergency of the examples was substantially better than that of the standard detergent.
In combination with the detergency results of Table 5, table 6, the detergency of examples was comparable to or better than that of commercially available detergents, and the detergency of examples was in accordance with the basic market demand, which was viable.
As can be seen from the detergency results of examples 1,2 and 3, within a certain range, the formula has a better improving effect on the detergency of the formula due to the decrease of the MES proportion and the increase of the AES proportion.
As can be seen from the detergency results of examples 5 and 6 and comparative examples 4 and 5, the detergency of the formulations increased with the increase in the proportion of AES and LAS as the proportion of MES decreases, and it is seen that AES and LAS have a better improving effect on the detergency of the formulations.
As can be seen from comparison of detergency results of examples and comparative examples 4 and 5, MES, AES, LAS, when it is required to compound within the ratio specified in the present invention, detergency performance can be ensured while the irritation of the system is maintained in the range of light irritation. Comparative examples 4 and 5, when LAS exceeds the ratio specified in the present invention, the detergency was improved to some extent but the system was in a medium-or near-strongly-stimulated state. MES, AES, LAS can be obtained, and the soil release performance and the low stimulation effect can be achieved only by compounding the MES, AES, LAS in the proportion specified by the invention.
From the detergency results of examples 4,5 and 6, it can be seen that the detergency of the formulation remained unchanged with the addition of the functional surfactant AG-U30. It can be seen that AG-U30 has a detergency effect on the formulation comparable to the remaining surface activity in the formulation.
As can be seen from the detergency results of comparative examples 4 and 5, when a small amount of AG-U30 and the amphoteric surfactant were compounded in the formulation, the detergency of the formulation was equivalent, and the effect of AG-U30 and the amphoteric surfactant in the detergency was substantially equivalent.
Test example 3
The test example summones 30 volunteers for the hand feeling test after washing of the samples prepared in the examples and comparative examples, and the volunteers were examined for 1 month of trial of the samples prepared in the examples and comparative examples, and scored the hand feeling after washing of the samples in the range of 1 to 10, respectively. The higher the score, the better the hand after washing, whereas the worse the hand, the test criteria are shown in table 8 and the test results are shown in table 7.
Table 7 hand care detergent example hand feel scoring results
Table 8 hand feel scoring criteria after hand care detergent wash
From the hand feel scoring results in Table 7, it can be seen that the hand feel after washing in the examples is generally better than the hand feel after washing in the comparative examples, the hand feel after washing in the examples is better, and the examples are feasible.
The examples have better hand feeling performance, compared with comparative example 1, the examples can obviously reduce the irritation of LAS and AES by compounding MES, and obviously improve the hand feeling after washing.
From the hand feel scores of examples 1,2 and 3, it can be seen that the system gradually decreases the comfort after skin washing as the MES content decreases and the AES content increases and the hand feel performance after washing decreases. Because the structure of the fatty acid methyl ester part in the MES is similar to that of the fatty acid glyceride in the skin, when the MES is contacted with the skin, an oil film can be formed on the surface of the skin, so that the water loss of the skin is reduced. Thus, in the system of the present invention, the higher the MES content of the sample, the milder the skin and the more pleasant the hand.
As can be seen from comparison of the hand feel scores of examples and comparative examples 4 and 5, MES, AES, LAS, when formulated within the proportions specified in the present invention, can ensure that the soil release properties and system irritation remain within the light irritation range while having a relatively good hand feel performance. When LAS exceeds the proportion specified in the invention, the detergency is improved to a certain extent, but the system is in a medium-stimulus or near-strong-stimulus state.
Examples compared to comparative examples 2,3, the examples had better hand after washing than comparative examples 2,3. The MES is compounded with AES and LAS in a certain proportion or is supplemented with a functional surfactant AG-U30, and the hand feeling after washing of the system is better than that of a formula system with special auxiliary agents of nonionic surfactant, fat-rich agent and humectant. The examples have obvious economic advantages compared with comparative examples 2 and 3, the conventional surfactant LAS, AES and green anionic surfactant MES are compounded, and compared with a formula system of special auxiliary agents added with various lipid-rich agents and humectants, the formula is economic, the cost performance is higher, the production process is simple, and the feasibility is higher.
As can be seen from the hand feel scoring results of examples 4,5 and 6 and comparative examples 4 and 5, the effect of improving the hand feel after washing is more obvious when AG-U30 is compounded in the system, and the hand feel comfort after washing is improved along with the increase of the content of AG-U30. Because AG-U30 can cooperate with MES, the lipophilic group of AG-U30 assists the fatty acid methyl ester part of MES to form a layer of oil film on the skin surface, so that the water loss of the skin is reduced. Meanwhile, the hydrophilic group of AG-U30 can form a hydrogen bond with water molecules around the skin, and a layer of protective film is formed on the skin, so that the loss of skin moisture is further reduced, the moisture is locked, and the skin is helped to keep moist and soft.
Test example 4
The test examples evaluate the heat and cold stability with reference to the specifications in GB/T9985 "detergent for hand dishwashing". The heat-resistant stability, which is maintained at (40.+ -. 2) °C for 24 hours, shows no significant change from the time of the experiment after the temperature was returned to room temperature, and shows good stability, marked as "V", the cold-resistant stability, which is maintained at (-5.+ -. 2) °C for 24 hours, shows no significant change from the time of the experiment after the temperature was returned to room temperature, and the result is shown in Table 9. The examples were satisfactory in both high and low temperature stability, and the liquid was in a uniform transparent state when room temperature (25 ℃) was restored.
Table 9 example stability results
While the embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. Furthermore, embodiments of the invention and features of the embodiments may be combined with each other without conflict.

Claims (10)

1. The hand-protecting detergent is characterized by comprising the components of fatty acid methyl ester sodium sulfonate, straight-chain sodium alkylbenzenesulfonate and fatty alcohol polyoxyethylene ether sodium sulfate.
2. The hand-protecting detergent disclosed by claim 1 is characterized by comprising the following components in parts by weight of 7.2-27:0.3-5:2-12.85 of fatty acid methyl ester sodium sulfonate, straight-chain sodium alkylbenzene sulfonate and fatty alcohol polyoxyethylene ether sodium sulfate.
3. The hand cleanser essence of claim 1, wherein the hand cleanser essence further comprises a copolymer of an acrylic polymer grafted polyether compound.
4. A hand cleaner according to claim 3 wherein the copolymer of an acrylic polymer grafted polyether compound comprises the structure of formula I or formula II:
R 1 is selected from one of the following structures:
Wherein a is 0 to 25, b is 0 to 8, z is 0 to 25, y (x+z) is 0.1 to 0.4, n is a positive integer of 2 to 14, and m is a positive integer of 2 to 12.
5. The hand-protecting detergent disclosed by claim 3, wherein the hand-protecting detergent comprises, by weight, 5-30 parts of fatty acid methyl ester sodium sulfonate, 0.3-10 parts of linear alkyl benzene sodium sulfonate and 2-15 parts of fatty alcohol polyoxyethylene ether sodium sulfate.
6. The hand cleaner of claim 3, wherein the hand cleaner further comprises: and the amphoteric surfactant comprises at least one of an amino acid surfactant, a betaine surfactant, an imidazoline surfactant and an amine oxide surfactant.
7. The hand cleanser essence of claim 6, further comprising an auxiliary agent comprising a chelating agent, a fragrance, a preservative and an inorganic salt.
8. The hand cleanser essence of claim 7, wherein the chelating agent comprises at least one of ethylenediamine tetraacetate, diethylenetriamine pentaacetate, methylglycine diacetate, glutamic acid diacetate, and sodium citrate dihydrate.
9. A method for preparing the hand-protecting detergent according to any one of claims 1 to 8, which is characterized by comprising the step of mixing the components of the hand-protecting detergent.
10. Use of the hand lotion according to any one of claims 1 to 8 in the field of household chemicals.
CN202411446034.3A 2024-10-16 2024-10-16 A kind of hand cleaning liquid and its preparation method and application Pending CN119410416A (en)

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