CN119303124A - Sterilization device and sterilization process for production of vitamin B6 injection - Google Patents
Sterilization device and sterilization process for production of vitamin B6 injection Download PDFInfo
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- CN119303124A CN119303124A CN202411536913.5A CN202411536913A CN119303124A CN 119303124 A CN119303124 A CN 119303124A CN 202411536913 A CN202411536913 A CN 202411536913A CN 119303124 A CN119303124 A CN 119303124A
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Abstract
本发明涉及灭菌技术领域，具体涉及维生素B6注射液生产用灭菌装置及其灭菌工艺，包括灭菌箱，灭菌箱的两侧内壁对称开设有矩形孔，灭菌箱内设有传送带，传送带的两端分别贯穿两个矩形孔，灭菌箱安装有用于驱动传送带对安瓿瓶进行传送的驱动机构；灭菌箱的两侧对称设有与矩形孔相适配的箱门，灭菌箱的两侧分别固定连接有第四液压伸缩杆，且第四液压伸缩杆的伸缩端和箱门固定连接；高温蒸汽直接吹向每个安瓿瓶，以使安瓿瓶和注射液灭菌效果更佳，提高了灭菌后包装的维生素B6注射液的质量。
The invention relates to the field of sterilization technology, and in particular to a sterilization device for producing vitamin B6 injection and a sterilization process thereof, comprising a sterilization box, wherein rectangular holes are symmetrically opened on inner walls on both sides of the sterilization box, a conveyor belt is arranged in the sterilization box, two ends of the conveyor belt respectively penetrate two rectangular holes, and the sterilization box is equipped with a driving mechanism for driving the conveyor belt to convey ampoules; box doors adapted to the rectangular holes are symmetrically arranged on both sides of the sterilization box, fourth hydraulic telescopic rods are respectively fixedly connected on both sides of the sterilization box, and the telescopic ends of the fourth hydraulic telescopic rods are fixedly connected to the box doors; high-temperature steam is directly blown to each ampoule bottle, so that the sterilization effect of the ampoule bottle and the injection liquid is better, and the quality of the vitamin B6 injection liquid packaged after sterilization is improved.
Description
Technical Field
The invention relates to the technical field of sterilization, in particular to a sterilization device and a sterilization process for vitamin B6 injection production.
Background
The vitamin B6 injection is mainly used for preventing and treating vitamin B6 deficiency, has various effects and functions, and is required to be injected into an ampoule bottle when being produced, then the ampoule bottle filled with the injection is transported into a sterilization box through a cart, and the ampoule bottle and the injection are sterilized by high-temperature steam flowing in the sterilization box.
However, it is worth thinking that the ampoule bottles are generally placed in the sterilizing box in a disordered way, so that the condition that steam high-temperature steam is directly blown to each ampoule bottle possibly causes unsatisfactory sterilizing effects of partial injection and ampoule bottles, the quality problem of the vitamin B6 injection packaged after sterilization is easy to occur, and certain limitation exists.
Thus, there is a need for a related installation that is more compatible with the needs of use in order to solve the above-mentioned problems.
Disclosure of Invention
Accordingly, the present invention is directed to a sterilization device and a sterilization process for vitamin B6 injection production, which solves the problem that the ampoule bottles are generally placed in a sterilization box in a disordered manner, and high-temperature steam cannot be ensured to be directly blown to each ampoule bottle.
Based on the above purpose, the invention provides a sterilization device for vitamin B6 injection production, which comprises a sterilization box, wherein rectangular holes are symmetrically formed in the inner walls of the two sides of the sterilization box, a conveyor belt is arranged in the sterilization box, the two ends of the conveyor belt respectively penetrate through the two rectangular holes, a driving mechanism for driving the conveyor belt to convey ampoule bottles is arranged in the sterilization box, box doors matched with the rectangular holes are symmetrically arranged on the two sides of the sterilization box, fourth hydraulic telescopic rods are respectively and fixedly connected on the two sides of the sterilization box, and the telescopic ends of the fourth hydraulic telescopic rods are fixedly connected with the box doors;
Two side plates positioned above the conveyor belt are arranged in the sterilization box, the end parts of the side plates are fixedly connected with guide plates, a plurality of position control assemblies which are sequentially arranged are arranged between the two side plates, and a sterilization mechanism for sterilization is arranged in the sterilization box;
Each group of position control assembly comprises two limiting plates, a plurality of groups of material guiding structures are arranged in the sterilizing box and are connected with the end parts of the two limiting plates in the corresponding position control assembly, and a spacing adjusting structure for respectively adjusting the positions of the two side plates and the plurality of limiting plates is arranged in the sterilizing box.
Optionally, the interval adjustment structure includes two sets of supporting elements that set up in the sterilization case, and every supporting element of group includes a plurality of mounts that arrange in proper order, and the inner wall fixed connection of mount and sterilization case, rotates on the mount and is connected with the pivot, the first gear of bottom fixedly connected with of pivot, curb plate and limiting plate fixedly connected with first pinion rack respectively, and first pinion rack meshes with corresponding first gear, curb plate and limiting plate are connected through the guide respectively with corresponding mount, and the rotation unit that is used for driving the pivot rotation is installed to the sterilization case.
Optionally, the guide piece includes fixed mounting in the uide bushing of mount bottom, two guide posts of fixedly connected with respectively on curb plate and the limiting plate, and the tip of guide post is located corresponding uide bushing.
Optionally, the rotation unit includes two first movable seats that set up in the sterilization case, two first movable seats cooperate with two sets of supporting unit respectively, first movable seat fixed mounting has a plurality of second pinion rack, the top fixedly connected with second gear of pivot, and the second gear meshes with corresponding second pinion rack, first movable seat fixed mounting has two first supporting parts, sterilization incasement fixedly connected with four second supporting parts, second supporting part fixed mounting has first hydraulic telescoping rod, and four first hydraulic telescoping rod's output respectively with four first supporting parts fixed connection.
Optionally, the guide structure includes a plurality of fly leaf that sets up in the sterilization case, the quantity that fly leaf and position control subassembly set up is unanimous, fly leaf fixed mounting has the arc that is located between two guide plates, the bottom rotation of fly leaf is connected with two swing boards, the spout has been seted up on the swing board, the slip is equipped with the slide in the spout, the inner wall of slide and spout is through a plurality of compression spring connection, two adjacent slides rotate with the tip of two limiting plates in every group position control subassembly respectively and be connected, the guide way has been seted up on the fly leaf, the slip is equipped with the guide plate in the guide way, and guide plate and corresponding mount fixed connection.
Optionally, be equipped with the movable frame in the sterilization case, sterilization incasement fixedly connected with a plurality of third supporting parts, third supporting part fixed mounting has the second hydraulic telescoping rod, the output and the movable frame fixed connection of second hydraulic telescoping rod, the movable frame install with the promotion unit of fly leaf looks adaptation.
Optionally, the pushing unit includes fixed mounting in the backup pad at fly leaf top, is equipped with the second movable seat in the sterilization case, and movable frame fixed mounting has a plurality of third hydraulic telescoping rods, and the flexible end and the second movable seat fixed connection of third hydraulic telescoping rod, and second movable seat fixed mounting has a plurality of press posts, and presses the post and the unanimous of the number that the backup pad set up, presses the one end that the post kept away from the second movable seat and runs through movable frame.
Optionally, the sterilization mechanism includes the heating cabinet of fixed mounting in the sterilization case, the air intake department fixedly connected with inlet hood of heating cabinet, the air outlet department fixedly connected with outlet hood of heating cabinet, the bottom fixedly connected with of outlet hood a plurality of outlet duct, the bottom rotation of outlet duct is connected with a plurality of gas-collecting shells, the bottom fixedly connected with first head of giving vent to anger of gas-collecting shell, the bottom fixedly connected with of gas-collecting shell two slope sets up the second head of giving vent to anger, and two adjacent second head symmetries set up in the both sides of first head of giving vent to anger, the outside fixed cover of gas-collecting shell is equipped with the third gear, the top fixedly connected with of movable frame a plurality of mounting panels, and the mounting panel is unanimous with the quantity that the outlet duct set up, mounting panel fixed mounting has a plurality of third pinion, and third gear and corresponding third pinion mesh mutually, sterilization case installs with inlet hood matched with circulation unit of bleeding.
Optionally, the circulation air extraction unit includes two fixed mounting shell of bleeding on the sterilization case, and two shell symmetries of bleeding set up in the both sides of heating cabinet, and a plurality of air extraction holes that are located the sterilization incasement have been seted up to the bottom of shell of bleeding, and sterilization case fixed mounting has two air pumps, and the input of air pump and the output of shell of bleeding are connected through first connecting pipe, and the output of air pump and the input of inlet hood pass through the second connecting pipe and are connected.
The invention also provides a sterilization process for producing the vitamin B6 injection, which comprises the sterilization device for producing the vitamin B6 injection, and comprises the following steps:
according to the specification of the ampoule bottle, the positions of the two side plates and the plurality of limiting plates are respectively adjusted through a spacing adjusting structure, so that the spacing between the side plate and the adjacent limiting plate and the spacing between the adjacent two limiting plates in the adjacent two groups of position control assemblies are at preset values;
driving the box door to move upwards through a fourth hydraulic telescopic rod so as to open the rectangular hole, driving the conveyor belt to convey the ampoule bottles through the driving mechanism so as to enable the ampoule bottles to move into the sterilization box through the corresponding rectangular hole, and guiding the ampoule bottles through two guide plates and a plurality of groups of guide structures;
The ampoule bottles are respectively moved between the side plate and an adjacent limiting plate and between two adjacent limiting plates in two adjacent groups of position control assemblies, the positions of the ampoule bottles are limited through the side plate and the limiting plates, so that the ampoule bottles are orderly placed on a conveyor belt, and a box door is driven to move downwards through a fourth hydraulic telescopic rod, so that two rectangular holes are closed;
And fourthly, driving the conveyor belt to periodically rotate forwards and reversely through the driving mechanism, changing the position of the ampoule bottles in the sterilizing box, sterilizing the ordered ampoule bottles and injection through the sterilizing mechanism, directly blowing high-temperature steam to each ampoule bottle, driving the box door to move upwards through the fourth hydraulic telescopic rod after sterilization is finished, and discharging the ampoule bottles from the corresponding rectangular holes through the conveyor belt.
The ampoule bottle sterilizing device has the beneficial effects that the conveying belt is driven by the driving mechanism to convey the ampoule bottles, so that the ampoule bottles move into the sterilizing box through the rectangular holes, the ampoule bottles are guided by the two guide plates and the plurality of groups of guide structures, the ampoule bottles respectively move between the side plate and the adjacent limiting plate and between the adjacent limiting plates in the adjacent two groups of position control assemblies, the positions of the ampoule bottles are limited by the side plate and the limiting plate, the ampoule bottles are orderly placed on the conveying belt, the sterilizing mechanism is used for sterilizing the orderly ampoule bottles and injection, and high-temperature steam is directly blown to each ampoule bottle, so that the ampoule bottles and the injection are better in sterilizing effect, and the quality of the vitamin B6 injection packaged after sterilization is improved.
Drawings
In order to more clearly illustrate the invention or the technical solutions of the prior art, the drawings which are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only of the invention and that other drawings can be obtained from them without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present invention;
FIG. 2 is a schematic view of the structure of the interior of the sterilization box according to the embodiment of the present invention;
FIG. 3 is a schematic view of the structure of an outlet pipe according to an embodiment of the present invention;
FIG. 4 is a schematic view of an embodiment of an air extraction shell;
FIG. 5 is a schematic view of a combined structure of a side plate and a limiting plate according to an embodiment of the present invention;
FIG. 6 is a schematic view showing the structure of the swing plate and the slide plate detached according to the embodiment of the invention;
FIG. 7 is a schematic structural view of a first movable seat according to an embodiment of the present invention;
fig. 8 is a schematic structural diagram of a movable frame according to an embodiment of the invention.
Marked in the figure as:
1. A sterilization box; 2, rectangular holes, 3, a conveyor belt, 4, a side plate, 5, a guide plate, 6, a limit plate, 7, a movable plate, 8, an arc plate, 9, a fixed frame, 10, a swing plate, 11, a slide plate, 12, a slide groove, 13, a compression spring, 14, a guide plate, 15, a guide groove, 16, a rotating shaft, 17, a first gear, 18, a first toothed plate, 19, a guide sleeve, 20, a guide column, 21, a first movable seat, 22, a second toothed plate, 23, a first supporting part, 24, a second supporting part, 25, a first hydraulic telescopic rod, 26, a movable frame, 27, a third supporting part, 28, a second hydraulic telescopic rod, 29, a second movable seat, 30, a pressing column, 31, a third hydraulic telescopic rod, 32, a supporting plate, 33, a heating box, 34, an air inlet cover, 35, an air outlet cover, 36, an air outlet pipe, 37, an air collecting shell, 38, a first air outlet head, 39, a second air outlet head, 40, a second gear, 41, 42, a third toothed plate, 43, a movable frame, 27, a third hydraulic telescopic rod, a third supporting part, 28, a second connecting pipe, a fourth air pump, a fourth connecting pipe and a fourth connecting pipe.
Detailed Description
The present invention will be further described in detail with reference to specific embodiments in order to make the objects, technical solutions and advantages of the present invention more apparent.
The sterilization device for vitamin B6 injection production provided by the embodiment, as shown in fig. 1,2 and 5, comprises a sterilization box 1, rectangular holes 2 are symmetrically formed in the inner walls of two sides of the sterilization box 1, a conveyor belt 3 is arranged in the sterilization box 1, two ends of the conveyor belt 3 respectively penetrate through the two rectangular holes 2, a driving mechanism for driving the conveyor belt 3 to convey ampoule bottles is arranged in the sterilization box 1, box doors 49 matched with the rectangular holes 2 are symmetrically arranged on two sides of the sterilization box 1, fourth hydraulic telescopic rods 50 are fixedly connected to two sides of the sterilization box 1 respectively, and telescopic ends of the fourth hydraulic telescopic rods 50 are fixedly connected with the box doors 49;
Two side plates 4 positioned above the conveyor belt 3 are arranged in the sterilization box 1, the end parts of the side plates 4 are fixedly connected with guide plates 5, a plurality of position control assemblies which are sequentially arranged are arranged between the two side plates 4, and a sterilization mechanism for sterilization is arranged in the sterilization box 1;
Each group of position control components comprises two limiting plates 6, a plurality of groups of material guiding structures are arranged in the sterilization box 1 and are connected with the end parts of the two limiting plates 6 in the corresponding position control components, a spacing adjusting structure used for adjusting the positions of the two side plates 4 and the plurality of limiting plates 6 respectively is arranged in the sterilization box 1, the driving mechanism drives the conveying belt 3 to convey the ampoule bottles through the rectangular holes 2 so that the ampoule bottles move into the sterilization box 1, the two guide plates 5 and the plurality of groups of material guiding structures guide the ampoule bottles, the ampoule bottles move between the side plate 4 and the adjacent limiting plate 6 and between the adjacent two limiting plates 6 in the adjacent two groups of position control components respectively, the positions of the ampoule bottles are limited through the side plate 4 and the limiting plate 6, so that the ampoule bottles are orderly placed on the conveying belt 3, the ampoule bottles and injection are sterilized through the sterilizing mechanism, high-temperature steam is directly blown to each ampoule bottle, so that the sterilizing effect of the ampoule bottles and the injection is better, and the quality of vitamin B6 injection packaged after sterilization is improved.
In some optional embodiments, as shown in fig. 2, fig. 5, fig. 6 and fig. 7, the interval adjusting structure comprises two groups of supporting units arranged in the sterilization box 1, each group of supporting units comprises a plurality of fixing frames 9 which are sequentially arranged, the fixing frames 9 are fixedly connected with the inner wall of the sterilization box 1, a rotating shaft 16 is rotationally connected on the fixing frames 9, a first gear 17 is fixedly connected at the bottom end of the rotating shaft 16, a side plate 4 and a limiting plate 6 are respectively and fixedly connected with a first toothed plate 18, the first toothed plate 18 is meshed with the corresponding first gear 17, the side plate 4 and the limiting plate 6 are respectively connected with the corresponding fixing frames 9 through a guide piece, the sterilization box 1 is provided with a rotation unit for driving the rotating shaft 16 to rotate, the guide piece comprises a guide sleeve 19 fixedly arranged at the bottom end of the fixing frame 9, the end of the guide post 20 is positioned in the corresponding guide sleeve 19, the rotation unit comprises two first movable seats 21 arranged in the sterilization box 1, the two first movable seats 21 are respectively matched with the two groups of supporting units, the first movable seats 21 are respectively connected with the corresponding second movable seats 21, the top ends of the first movable seats 21 are fixedly connected with the second movable seats 22, the first movable seats 22 are respectively connected with the second movable seats 22 and the second movable seats 22, the first fixed seats 22 are fixedly connected with the second movable seats 25, the first fixed to the second fixed support parts 22 and the fourth fixed support parts 25 are fixedly connected with the fourth movable seats 22, the fourth fixed support parts are fixedly connected with the fourth movable seats 25, and the fourth fixed support parts are respectively, and the fourth fixed support shafts 20, and the fourth fixed supports are respectively, and are respectively connected;
the first supporting part 23 and the first movable seat 21 are driven to move through the first hydraulic telescopic rod 25, the first movable seat 21 drives the second toothed plate 22 to move, the second toothed plate 22 drives the rotating shaft 16 and the first gear 17 to synchronously rotate through the second gear 40, the first gear 17 drives the corresponding first toothed plate 18 to move, the first toothed plate 18 can drive the corresponding side plate 4 or the limiting plate 6 to move, the positions of the side plate 4 and the limiting plate 6 are adjusted, the side plate 4 and the limiting plate 6 drive the corresponding guide post 20 to slide relative to the guide sleeve 19 and the fixed frame 9, and the side plate 4 and the limiting plate 6 move smoothly in the horizontal direction through the design of the guide post 20 and the guide sleeve 19.
In some alternative specific embodiments, as shown in fig. 2, 5, 6 and 8, the material guiding structure comprises a plurality of movable plates 7 arranged in the sterilizing box 1, the number of the movable plates 7 and the number of the position control components are consistent, the movable plates 7 are fixedly provided with arc plates 8 positioned between the two guide plates 5, the bottoms of the movable plates 7 are rotatably connected with two swinging plates 10, the swinging plates 10 are provided with sliding grooves 12, sliding plates 11 are slidably arranged in the sliding grooves 12, the sliding plates 11 are connected with the inner walls of the sliding grooves 12 through a plurality of compression springs 13, the adjacent two sliding plates 11 are respectively rotatably connected with the end parts of the two limiting plates 6 in each group of position control components, the movable plates 7 are provided with guide grooves 15, the guide plates 14 are slidably arranged in the guide grooves 15, and the guide plates 14 are fixedly connected with corresponding fixing frames 9, the sterilization box 1 is internally provided with a movable frame 26, a plurality of third supporting parts 27 are fixedly connected in the sterilization box 1, the third supporting parts 27 are fixedly provided with second hydraulic telescopic rods 28, the output ends of the second hydraulic telescopic rods 28 are fixedly connected with the movable frame 26, the movable frame 26 is provided with a pushing unit matched with the movable plate 7, the pushing unit comprises a supporting plate 32 fixedly arranged at the top of the movable plate 7, the sterilization box 1 is internally provided with a second movable seat 29, the movable frame 26 is fixedly provided with a plurality of third hydraulic telescopic rods 31, the telescopic ends of the third hydraulic telescopic rods 31 are fixedly connected with the second movable seat 29, the second movable seat 29 is fixedly provided with a plurality of pressing columns 30, the number of the pressing columns 30 is identical with that of the supporting plate 32, and one end, far away from the second movable seat 29, of the pressing columns 30 penetrates through the movable frame 26;
When two limiting plates 6 in each group of position control assemblies move, the limiting plates 6 drive the sliding plates 11 to rotate, the inclination angles of the sliding plates 11 and the swinging plates 10 are changed, the swinging plates 10 rotate relative to the movable plates 7, the swinging plates 10 drive the movable plates 7 and the arc plates 8 to slide horizontally relative to the fixed frames 9 and the guide plates 14, after the positions of the limiting plates 6 are adjusted, ampoule bottles are guided by the arc plates 8, the ampoule bottles are guided by the swinging plates 10 and the sliding plates 11, the final conveyor belt 3 drives the ampoule bottles to move to a position between the side plate 4 and one adjacent limiting plate 6 or between two adjacent limiting plates 6 in two adjacent groups of position control assemblies, the third hydraulic telescopic rod 31 drives the second movable seat 29 and the pressing column 30 to move horizontally, the initial distance between the pressing column 30 and the supporting plate 32 is adjusted, then the second hydraulic telescopic rod 28 drives the movable frame 26 to reciprocate horizontally relative to the sterilizing box 1, the movable frame 26 drives the pressing column 30 to reciprocate horizontally through the third hydraulic telescopic rod 31 and the second movable seat 29, so that the pressing column 30 periodically pushes the supporting plate 32 to move for a certain distance, the supporting plate 32 drives the movable plate 7 and the arc plate 8 to move so as to enable the swinging plate 10 to slide relative to the sliding plate 11, the compression spring 13 is in a compressed state, the inclination angles of the swinging plate 10 and the sliding plate 11 are changed, when the pressing column 30 is not contacted with the supporting plate 32 any more, the compression spring 13 drives the swinging plate 10 to reversely slide relative to the sliding plate 11, the swinging plate 10 and the sliding plate 11 are restored to the initial position relative to the limiting plate 6, the movable frame 26 is driven to reciprocate horizontally through the second hydraulic telescopic rod 28, so that the swinging plate 10 and the sliding plate 11 reciprocate, ampoule bottles are pushed to move on the conveyor belt 3 through the swinging plate 10 and the sliding plate 11, the position of the ampoule bottle is changed, and the ampoule bottle is prevented from being blocked among a plurality of material guiding structures.
In some alternative specific embodiments, as shown in fig. 1,2, 3,4 and 8, the sterilization mechanism comprises a heating box 33 fixedly installed in the sterilization box 1, an air inlet cover 34 is fixedly connected to an air inlet of the heating box 33, an air outlet cover 35 is fixedly connected to an air outlet of the heating box 33, a plurality of air outlet pipes 36 are fixedly connected to the bottom of the air outlet cover 35, a plurality of air collecting shells 37 are rotatably connected to the bottom of the air outlet pipes 36, a first air outlet head 38 is fixedly connected to the bottom of the air collecting shells 37, two second air outlet heads 39 which are obliquely arranged are fixedly connected to the bottom of the air collecting shells 37, two adjacent second air outlet heads 39 are symmetrically arranged on two sides of the first air outlet head 38, a third gear 48 is fixedly sleeved outside the air collecting shells 37, the top of the movable frame 26 is fixedly connected with a plurality of mounting plates 41, the number of the mounting plates 41 is consistent with that of the air outlet pipes 36, the mounting plates 41 are fixedly provided with a plurality of third toothed plates 42, third gears 48 are meshed with the corresponding third toothed plates 42, the sterilizing box 1 is provided with a circulating air suction unit matched with the air inlet cover 34, the circulating air suction unit comprises two air suction shells 43 fixedly arranged on the sterilizing box 1, the two air suction shells 43 are symmetrically arranged on two sides of the heating box 33, the bottom ends of the air suction shells 43 are provided with a plurality of air suction holes 44 positioned in the sterilizing box 1, the sterilizing box 1 is fixedly provided with two air pumps 45, the input ends of the air pumps 45 are connected with the output ends of the air suction shells 43 through first connecting pipes 46, and the output ends of the air pumps 45 are connected with the input ends of the air inlet cover 34 through second connecting pipes 47;
External high-temperature steam enters the heating box 33 through the air inlet cover 34, the high-temperature steam flows into the air collecting shell 37 through the air outlet cover 35 and the air outlet pipe 36, the final high-temperature steam is blown to the ampoule bottle through the first air outlet head 38 and the second air outlet head 39, after the ampoule bottle is sterilized at high temperature by the high-temperature steam, the high-temperature steam with reduced heat moves to two sides, the air pump 45 is started, the high-temperature steam flows back into the air outlet shell 43 through the air outlet hole 44, the air pump 45 extracts the steam in the sterilizing box 1 through the first connecting pipe 46 and the air outlet shell 43, the steam flows into the air inlet cover 34 through the second connecting pipe 47, the high-temperature steam heats the steam flowing out of the air inlet cover 34 through the heating box 33, the steam keeps a preset temperature, hot air circulation is formed, damage of energy is reduced, and when the movable frame 26 moves reciprocally in the horizontal direction, the movable frame 26 drives the third toothed plate 42 to move through the mounting plate 41, the third toothed plate 48 drives the air collecting shell 37 to rotate relative to the air outlet pipe 36, the second air outlet head 39 can rotate, the air outlet direction of the second air outlet head 39 is changed, and the ampoule bottle is sterilized more uniformly, the sterilizing effect of the injection liquid is improved, and the sterilizing effect of the injection liquid is sterilized more uniformly.
This embodiment also provides a sterilization process for vitamin B6 injection production, including the sterilization apparatus for vitamin B6 injection production as described above, comprising the steps of:
According to the specification of the ampoule bottle, the positions of the two side plates 4 and the plurality of limiting plates 6 are respectively adjusted through a spacing adjusting structure, so that the spacing between the side plate 4 and the adjacent limiting plate 6 and the spacing between the adjacent two limiting plates 6 in the adjacent two groups of position control assemblies are at preset values;
Driving a box door 49 to move upwards through a fourth hydraulic telescopic rod 50 so as to open the rectangular hole 2, driving a conveyor belt 3 to convey ampoule bottles through a driving mechanism so as to enable the ampoule bottles to move into a sterilization box 1 through the corresponding rectangular hole 2, and guiding the ampoule bottles through two guide plates 5 and a plurality of groups of guide structures;
The ampoule bottles are respectively moved between the side plate 4 and the adjacent limiting plate 6 and between the adjacent two limiting plates 6 in the adjacent two groups of position control assemblies, the positions of the ampoule bottles are limited through the side plate 4 and the limiting plates 6, so that the ampoule bottles are orderly placed on the conveyor belt 3, and the box door 49 is driven to move downwards through the fourth hydraulic telescopic rod 50, so that the two rectangular holes 2 are closed;
and fourthly, driving the conveyor belt 3 to periodically rotate forwards and reversely through the driving mechanism, changing the position of the ampoule bottles in the sterilizing box 1, sterilizing the ordered ampoule bottles and injection through the sterilizing mechanism, directly blowing high-temperature steam to each ampoule bottle, driving the box door 49 to move upwards through the fourth hydraulic telescopic rod 50 after sterilization, and discharging the ampoule bottles from the corresponding rectangular holes 2 through the conveyor belt 3.
According to the specification of the ampoule bottles, the positions of the two side plates 4 and the plurality of limiting plates 6 are respectively adjusted through a spacing adjustment structure, so that the spacing between the side plate 4 and the adjacent limiting plate 6 and the spacing between the adjacent two limiting plates 6 in the adjacent two groups of position control assemblies are at preset values, the ampoule bottles are conveyed through the driving mechanism driving conveyor belt 3, so that the ampoule bottles move into the sterilization box 1 through the rectangular holes 2, the ampoule bottles are guided through the two guide plates 5 and the plurality of groups of guide structures, the ampoule bottles move to the positions between the side plate 4 and the adjacent limiting plate 6 and between the adjacent two limiting plates 6 in the adjacent two groups of position control assemblies respectively, the positions of the ampoule bottles are limited through the side plate 4 and the limiting plates 6, so that the ampoule bottles are orderly placed on the conveyor belt 3, the ampoule bottles and the injection are sterilized through the sterilizing mechanism, high-temperature steam is directly blown to each ampoule bottle, so that the sterilization effect of the ampoule bottles and the injection bottles is better, and the quality of the vitamin B6 injection packaged after sterilization is improved;
The first supporting part 23 and the first movable seat 21 are driven to move through the first hydraulic telescopic rod 25, the first movable seat 21 drives the second toothed plate 22 to move, the second toothed plate 22 drives the rotating shaft 16 and the first gear 17 to synchronously rotate through the second gear 40, the first gear 17 drives the corresponding first toothed plate 18 to move, the first toothed plate 18 can drive the corresponding side plate 4 or the limiting plate 6 to move, the positions of the side plate 4 and the limiting plate 6 are adjusted, the side plate 4 and the limiting plate 6 drive the corresponding guide post 20 to slide relative to the guide sleeve 19 and the fixed frame 9, and the side plate 4 and the limiting plate 6 move smoothly in the horizontal direction through the design of the guide post 20 and the guide sleeve 19;
When two limiting plates 6 in each group of position control assemblies move, the limiting plates 6 drive the sliding plates 11 to rotate, the inclination angles of the sliding plates 11 and the swinging plates 10 are changed, the swinging plates 10 rotate relative to the movable plates 7, the swinging plates 10 drive the movable plates 7 and the arc plates 8 to slide horizontally relative to the fixed frames 9 and the guide plates 14, after the positions of the limiting plates 6 are adjusted, ampoule bottles are guided by the arc plates 8, the ampoule bottles are guided by the swinging plates 10 and the sliding plates 11, the final conveyor belt 3 drives the ampoule bottles to move to a position between the side plate 4 and one adjacent limiting plate 6 or between two adjacent limiting plates 6 in two adjacent groups of position control assemblies, the third hydraulic telescopic rod 31 drives the second movable seat 29 and the pressing column 30 to move horizontally, the initial distance between the pressing column 30 and the supporting plate 32 is adjusted, then the second hydraulic telescopic rod 28 drives the movable frame 26 to reciprocate horizontally relative to the sterilizing box 1, the movable frame 26 drives the pressing column 30 to reciprocate horizontally through the third hydraulic telescopic rod 31 and the second movable seat 29, so that the pressing column 30 periodically pushes the supporting plate 32 to move for a certain distance, the supporting plate 32 drives the movable plate 7 and the arc plate 8 to move so as to enable the swinging plate 10 to slide relative to the sliding plate 11, the compression spring 13 is in a compressed state, the inclination angles of the swinging plate 10 and the sliding plate 11 are changed, when the pressing column 30 is not contacted with the supporting plate 32 any more, the compression spring 13 drives the swinging plate 10 to reversely slide relative to the sliding plate 11, the swinging plate 10 and the sliding plate 11 are restored to the initial position relative to the limiting plate 6, the movable frame 26 is driven to reciprocate horizontally through the second hydraulic telescopic rod 28, so that the swinging plate 10 and the sliding plate 11 reciprocate, ampoule bottles are pushed to move on the conveyor belt 3 through the swinging plate 10 and the sliding plate 11, changing the position of the ampoule bottle, and avoiding the ampoule bottle from being blocked among a plurality of material guiding structures;
External high-temperature steam enters the heating box 33 through the air inlet cover 34, the high-temperature steam flows into the air collecting shell 37 through the air outlet cover 35 and the air outlet pipe 36, the final high-temperature steam is blown to the ampoule bottle through the first air outlet head 38 and the second air outlet head 39, after the ampoule bottle is sterilized at high temperature by the high-temperature steam, the high-temperature steam with reduced heat moves to two sides, the air pump 45 is started, the high-temperature steam flows back into the air outlet shell 43 through the air outlet hole 44, the air pump 45 extracts the steam in the sterilizing box 1 through the first connecting pipe 46 and the air outlet shell 43, the steam flows into the air inlet cover 34 through the second connecting pipe 47, the high-temperature steam heats the steam flowing out of the air inlet cover 34 through the heating box 33, the steam keeps a preset temperature, hot air circulation is formed, damage of energy is reduced, and when the movable frame 26 moves reciprocally in the horizontal direction, the movable frame 26 drives the third toothed plate 42 to move through the mounting plate 41, the third toothed plate 48 drives the air collecting shell 37 to rotate relative to the air outlet pipe 36, the second air outlet head 39 can rotate, the air outlet direction of the second air outlet head 39 is changed, and the ampoule bottle is sterilized more uniformly, the sterilizing effect of the injection liquid is improved, and the sterilizing effect of the injection liquid is sterilized more uniformly.
It will be appreciated by persons skilled in the art that the above discussion of any embodiment is merely exemplary and is not intended to imply that the scope of the invention is limited to these examples, that combinations of technical features in the above embodiments or in different embodiments may also be implemented in any order, and that many other variations of the different aspects of the invention as described above exist, which are not provided in detail for the sake of brevity.
Claims (10)
1. The sterilization device for vitamin B6 injection production comprises a sterilization box (1), and is characterized in that rectangular holes (2) are symmetrically formed in the inner walls of two sides of the sterilization box (1), a conveyor belt (3) is arranged in the sterilization box (1), two ends of the conveyor belt (3) penetrate through the two rectangular holes (2) respectively, a driving mechanism for driving the conveyor belt (3) to convey ampoule bottles is arranged on the sterilization box (1), box doors (49) matched with the rectangular holes (2) are symmetrically arranged on two sides of the sterilization box (1), fourth hydraulic telescopic rods (50) are fixedly connected to two sides of the sterilization box (1) respectively, and telescopic ends of the fourth hydraulic telescopic rods (50) are fixedly connected with the box doors (49);
Two side plates (4) positioned above the conveyor belt (3) are arranged in the sterilization box (1), the end parts of the side plates (4) are fixedly connected with guide plates (5), a plurality of position control assemblies which are sequentially arranged are arranged between the two side plates (4), and a sterilization mechanism for sterilization is arranged in the sterilization box (1);
Each group of position control assembly comprises two limiting plates (6), a plurality of groups of material guiding structures are arranged in the sterilizing box (1), the material guiding structures are connected with the end parts of the two limiting plates (6) in the corresponding position control assembly, and a spacing adjusting structure for respectively adjusting the positions of the two side plates (4) and the plurality of limiting plates (6) is arranged in the sterilizing box (1).
2. The sterilization device for vitamin B6 injection production according to claim 1, wherein the interval adjustment structure comprises two groups of support units arranged in the sterilization box (1), each group of support units comprises a plurality of fixing frames (9) which are sequentially arranged, the fixing frames (9) are fixedly connected with the inner wall of the sterilization box (1), the fixing frames (9) are rotationally connected with rotating shafts (16), the bottom ends of the rotating shafts (16) are fixedly connected with first gears (17), the side plates (4) and the limiting plates (6) are respectively fixedly connected with first toothed plates (18), the first toothed plates (18) are meshed with the corresponding first gears (17), the side plates (4) and the limiting plates (6) are respectively connected with the corresponding fixing frames (9) through guide pieces, and the sterilization box (1) is provided with autorotation units for driving the rotating shafts (16).
3. The sterilization device for vitamin B6 injection production according to claim 2, wherein the guide piece comprises a guide sleeve (19) fixedly installed at the bottom end of the fixing frame (9), two guide posts (20) are fixedly connected to the side plate (4) and the limiting plate (6) respectively, and the end parts of the guide posts (20) are located in the corresponding guide sleeves (19).
4. The sterilization device for vitamin B6 injection production according to claim 2, wherein the rotation unit comprises two first movable seats (21) arranged in the sterilization box (1), the two first movable seats (21) are respectively matched with the two groups of support units, the first movable seats (21) are fixedly provided with a plurality of second toothed plates (22), the top end of the rotating shaft (16) is fixedly connected with a second gear (40), the second gear (40) is meshed with the corresponding second toothed plates (22), the first movable seats (21) are fixedly provided with two first support parts (23), four second support parts (24) are fixedly connected in the sterilization box (1), the second support parts (24) are fixedly provided with first hydraulic telescopic rods (25), and the output ends of the four first hydraulic telescopic rods (25) are respectively fixedly connected with the four first support parts (23).
5. The sterilization device for vitamin B6 injection production according to claim 2, wherein the material guiding structure comprises a plurality of movable plates (7) arranged in the sterilization box (1), the number of the movable plates (7) and the number of the position control components are identical, the movable plates (7) are fixedly provided with arc plates (8) arranged between two guide plates (5), the bottoms of the movable plates (7) are rotationally connected with two swinging plates (10), sliding grooves (12) are formed in the swinging plates (10), sliding plates (11) are slidably arranged in the sliding grooves (12), the inner walls of the sliding plates (11) and the sliding grooves (12) are connected through a plurality of compression springs (13), the adjacent two sliding plates (11) are respectively rotationally connected with the end parts of two limiting plates (6) in each group of position control components, guide grooves (15) are formed in the movable plates (7), guide plates (14) are slidably arranged in the guide grooves (15), and the guide plates (14) are fixedly connected with corresponding fixing frames (9).
6. The sterilization device for vitamin B6 injection production according to claim 5, wherein a movable frame (26) is arranged in the sterilization box (1), a plurality of third supporting parts (27) are fixedly connected in the sterilization box (1), the third supporting parts (27) are fixedly provided with second hydraulic telescopic rods (28), the output ends of the second hydraulic telescopic rods (28) are fixedly connected with the movable frame (26), and a pushing unit matched with the movable plate (7) is arranged on the movable frame (26).
7. The sterilization device for vitamin B6 injection production according to claim 6, wherein the pushing unit comprises a supporting plate (32) fixedly mounted on the top of the movable plate (7), a second movable seat (29) is arranged in the sterilization box (1), a plurality of third hydraulic telescopic rods (31) are fixedly mounted on the movable frame (26), the telescopic ends of the third hydraulic telescopic rods (31) are fixedly connected with the second movable seat (29), a plurality of pressing columns (30) are fixedly mounted on the second movable seat (29), the number of the pressing columns (30) is identical with the number of the supporting plate (32), and one end, far away from the second movable seat (29), of the pressing columns (30) penetrates through the movable frame (26).
8. The sterilization device for vitamin B6 injection production according to claim 6, wherein the sterilization mechanism comprises a heating box (33) fixedly installed in the sterilization box (1), an air inlet of the heating box (33) is fixedly connected with an air inlet cover (34), an air outlet of the heating box (33) is fixedly connected with an air outlet cover (35), a plurality of air outlet pipes (36) are fixedly connected to the bottom of the air outlet cover (35), a plurality of air collecting shells (37) are rotatably connected to the bottom of the air outlet pipes (36), a first air outlet head (38) is fixedly connected to the bottom of the air collecting shells (37), two obliquely-arranged second air outlet heads (39) are fixedly connected to the bottom of the air collecting shells (37), two adjacent second air outlet heads (39) are symmetrically arranged on two sides of the first air outlet head (38), a third gear (48) is fixedly sleeved on the outer portion of the air collecting shells (37), a plurality of mounting plates (41) are fixedly connected to the top of the movable frame (26), the number of the mounting plates (41) is consistent with the number of the air outlet pipes (36), a third toothed plate (42) is fixedly installed on the bottom of the air collecting plates (41), two second toothed plates (42) are fixedly installed on the bottom of the air collecting shells (37), two second toothed plates (42) are meshed with the third gear (48), and the third toothed plates (34) are meshed with the third toothed plates (34) and meshed with the first toothed plate (34).
9. The sterilization device for vitamin B6 injection production according to claim 8, wherein the circulating air extraction unit comprises two air extraction shells (43) fixedly installed on the sterilization box (1), the two air extraction shells (43) are symmetrically arranged on two sides of the heating box (33), a plurality of air extraction holes (44) located in the sterilization box (1) are formed in the bottom end of the air extraction shells (43), two air pumps (45) are fixedly installed on the sterilization box (1), the input ends of the air pumps (45) are connected with the output ends of the air extraction shells (43) through first connecting pipes (46), and the output ends of the air pumps (45) are connected with the input ends of the air inlet hoods (34) through second connecting pipes (47).
10. The sterilization process for producing vitamin B6 injection, which comprises the sterilization device for producing vitamin B6 injection as set forth in claim 1, and is characterized by comprising the following steps:
According to the specification of the ampoule bottle, the positions of the two side plates (4) and the plurality of limiting plates (6) are respectively adjusted through a spacing adjustment structure, so that the spacing between the side plate (4) and the adjacent limiting plate (6) and the spacing between the adjacent two limiting plates (6) in the adjacent two groups of position control assemblies are at preset values;
Driving a box door (49) to move upwards through a fourth hydraulic telescopic rod (50) so as to open a rectangular hole (2), driving a conveying belt (3) through a driving mechanism to convey ampoule bottles, enabling the ampoule bottles to move into a sterilizing box (1) through the corresponding rectangular hole (2), and guiding the ampoule bottles through two guide plates (5) and a plurality of groups of guide structures;
The ampoule bottles are respectively moved between the side plate (4) and the adjacent limiting plate (6) and between the adjacent two limiting plates (6) in the two adjacent groups of position control assemblies, the positions of the ampoule bottles are limited through the side plate (4) and the limiting plates (6), so that the ampoule bottles are orderly placed on the conveyor belt (3), and the box door (49) is driven to move downwards through the fourth hydraulic telescopic rod (50), so that the two rectangular holes (2) are closed;
And fourthly, driving the conveyor belt (3) to periodically rotate forwards and reversely through the driving mechanism, changing the position of the ampoule bottles in the sterilizing box (1), sterilizing the ordered ampoule bottles and injection through the sterilizing mechanism, directly blowing high-temperature steam to each ampoule bottle, driving the box door (49) to move upwards through the fourth hydraulic telescopic rod (50) after sterilization, and discharging the ampoule bottles from the corresponding rectangular holes (2) through the conveyor belt (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411536913.5A CN119303124A (en) | 2024-10-31 | 2024-10-31 | Sterilization device and sterilization process for production of vitamin B6 injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411536913.5A CN119303124A (en) | 2024-10-31 | 2024-10-31 | Sterilization device and sterilization process for production of vitamin B6 injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN119303124A true CN119303124A (en) | 2025-01-14 |
Family
ID=94182433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411536913.5A Withdrawn CN119303124A (en) | 2024-10-31 | 2024-10-31 | Sterilization device and sterilization process for production of vitamin B6 injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN119303124A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2035131A1 (en) * | 1970-07-15 | 1972-01-20 | Sp Pk Bjuro Ch | Sterilising glass tubes - used in ampoule manufacture with steam |
| US3885915A (en) * | 1971-12-01 | 1975-05-27 | Tanabe Seiyaku Co | Method and apparatus for the sterilization of ampoules with pharmaceutical liquid therein |
| CN104880042A (en) * | 2015-05-21 | 2015-09-02 | 成都中牧生物药业有限公司 | Micro process for drying and sterilizing ampoule |
| CN209154594U (en) * | 2018-07-19 | 2019-07-26 | 武汉农大生物科技有限公司 | A kind of veterinary drug water medicament production ampere bottle dry sterilization device |
| CN212490814U (en) * | 2020-01-19 | 2021-02-09 | 浙江泰康药业集团有限公司 | Steam sterilizer for ampoule bottle |
| CN213822649U (en) * | 2020-11-30 | 2021-07-30 | 河南天致药业有限公司 | High-efficient sterilization device of injection form injection |
| CN118529687A (en) * | 2024-05-07 | 2024-08-23 | 武汉人福药业有限责任公司 | A feeding transmission device for ampoule bottle sterilization and baking |
-
2024
- 2024-10-31 CN CN202411536913.5A patent/CN119303124A/en not_active Withdrawn
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2035131A1 (en) * | 1970-07-15 | 1972-01-20 | Sp Pk Bjuro Ch | Sterilising glass tubes - used in ampoule manufacture with steam |
| US3885915A (en) * | 1971-12-01 | 1975-05-27 | Tanabe Seiyaku Co | Method and apparatus for the sterilization of ampoules with pharmaceutical liquid therein |
| CN104880042A (en) * | 2015-05-21 | 2015-09-02 | 成都中牧生物药业有限公司 | Micro process for drying and sterilizing ampoule |
| CN209154594U (en) * | 2018-07-19 | 2019-07-26 | 武汉农大生物科技有限公司 | A kind of veterinary drug water medicament production ampere bottle dry sterilization device |
| CN212490814U (en) * | 2020-01-19 | 2021-02-09 | 浙江泰康药业集团有限公司 | Steam sterilizer for ampoule bottle |
| CN213822649U (en) * | 2020-11-30 | 2021-07-30 | 河南天致药业有限公司 | High-efficient sterilization device of injection form injection |
| CN118529687A (en) * | 2024-05-07 | 2024-08-23 | 武汉人福药业有限责任公司 | A feeding transmission device for ampoule bottle sterilization and baking |
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