CN119242426A - A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens - Google Patents
A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens Download PDFInfo
- Publication number
- CN119242426A CN119242426A CN202411378106.5A CN202411378106A CN119242426A CN 119242426 A CN119242426 A CN 119242426A CN 202411378106 A CN202411378106 A CN 202411378106A CN 119242426 A CN119242426 A CN 119242426A
- Authority
- CN
- China
- Prior art keywords
- sampling
- mycobacterium tuberculosis
- sealing cover
- swab
- tongue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0051—Devices for taking samples of body liquids for taking saliva or sputum samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/06—Tubular
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/02—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by impregnation, e.g. using swabs or loops
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
本发明属于结核分支杆菌检测领域，具体涉及一种基于舌拭子标本的结核分枝杆菌收集及前处理装置，包括取样管、密封盖和取样拭子，所述取样管与密封盖螺纹连接，所述取样拭子设置在密封盖的中部，伸入取样管中，所述密封盖内设置有注入机构，所述注入机构中储存有培养液，所述取样拭子包括竖杆和取样板，所述竖杆为中空机构且与注入机构相连通，所述取样板设置在竖杆的取样端。本发明能够实现结核分枝杆菌舌拭子样本的收集及前处理，提高样本的采样率。
The present invention belongs to the field of tuberculosis mycobacterium detection, and specifically relates to a tuberculosis mycobacterium collection and pretreatment device based on a tongue swab specimen, comprising a sampling tube, a sealing cover and a sampling swab, wherein the sampling tube is threadedly connected to the sealing cover, the sampling swab is arranged in the middle of the sealing cover and extends into the sampling tube, an injection mechanism is arranged in the sealing cover, a culture fluid is stored in the injection mechanism, the sampling swab comprises a vertical rod and a sampling plate, the vertical rod is a hollow mechanism and is connected to the injection mechanism, and the sampling plate is arranged at the sampling end of the vertical rod. The present invention can realize the collection and pretreatment of tuberculosis mycobacterium tongue swab samples and improve the sampling rate of samples.
Description
Technical Field
The invention belongs to the field of mycobacterium tuberculosis detection, and particularly relates to a mycobacterium tuberculosis collection and pretreatment device based on a tongue swab specimen.
Background
The tongue swab is a sampling mode for detecting and sampling mycobacterium tuberculosis, when a sample is acquired, a patient is required to open the mouth to expose the oral cavity, so that medical staff or inspection staff can slightly wipe the tongue surface of the patient through the swab to acquire secretion, and the secretion is stored in a sealed sampling tube, so that later detection is facilitated.
However, no special tongue swab device for collecting and preprocessing based on mycobacterium tuberculosis exists, and the preprocessing aims mainly include (1) removing miscellaneous bacteria (decontamination) except mycobacterium and (2) liquefying samples for convenient detection. The Chinese patent No. 217006494U discloses an auxiliary device suitable for sputum specimen collection and pretreatment, which can only conduct pretreatment of a collection box on the sputum specimen, but is not suitable for collection of tongue surface samples, and the collection of multiple parts of the tongue surface needs to be considered during the collection of the tongue surface samples so as to improve the sampling rate, so that the sampling capability of a conventional cotton swab is limited, and the pretreatment of the tongue surface samples cannot be achieved.
Therefore, how to provide a device for collecting and preprocessing mycobacterium tuberculosis based on tongue swab specimens becomes a problem to be considered by those skilled in the art.
Disclosure of Invention
Aiming at the problems mentioned in the background art, the invention discloses a device for collecting and preprocessing mycobacterium tuberculosis based on a tongue swab specimen, the invention improves the sampling area of the swab through the arrangement of a sampling plate, realizes the preprocessing of the specimen through connecting the sampling swab with an injection mechanism, and specifically discloses the following technical scheme:
the utility model provides a mycobacterium tuberculosis collects and preprocessing device based on tongue swab sample, includes sampling tube, sealed lid and sampling swab, sampling tube and sealed lid threaded connection, sampling swab sets up in sealed middle part of lid, stretches into in the sampling tube, be provided with injection mechanism in the sealed lid, it has the culture solution to store in the injection mechanism, sampling swab includes montant and sampling plate, the montant is cavity mechanism and is linked together with injection mechanism, the sampling plate sets up the sampling end at the montant.
Further, the sampling plate is rectangular, a connecting pipe is arranged in the middle of the sampling plate, the connecting pipe is sleeved on the vertical rod, and a rubber anti-slip layer is arranged in the connecting pipe.
Further, a partition plate is arranged in the middle of the inside of the sampling tube, through holes are formed in the middle of the partition plate, corresponding to the vertical rods, and transverse holes used for the sampling plate to pass through are formed in two sides of the through holes.
Further, the top of sampling board is provided with the protection arch.
Furthermore, fluff inclined to the sealing cover direction is arranged on both sides of the sampling plate.
Further, the injection mechanism comprises a liquid bag and a push switch, the liquid bag is arranged in the sealing cover, the push switch is arranged at the top end of the liquid bag, a sliding groove is formed in one side of the sealing cover, and the push switch is limited in the sliding groove.
Further, the end part of the vertical rod is provided with a rubber film for sealing.
Further, the bottom of the sampling tube is provided with a conical bulge corresponding to the rubber film.
Further, the top of the conical bulge is hollow, and the bottom of the conical bulge is provided with a liquid outlet communicated with the top of the conical bulge.
The invention has the beneficial effects that through the integral structural design of the sealing cover and the sampling swab, the occupied space is small, the sampling plate and the culture solution can be separately protected, pollution is avoided, through the arrangement of the injection mechanism in the sealing cover, the pretreatment of the mycobacterium tuberculosis can be realized through the injection mechanism, the treated culture solution can be collected after standing, the sampling plate adopts the double-sided rectangular structural design, the sampling area is increased, and the sample on the surface of the tongue can be rapidly collected.
Drawings
FIG. 1 is a schematic diagram of a main body of the present invention;
FIG. 2 is a schematic view of the seal cap and sampling swab of the present invention;
FIG. 3 is a cross-sectional view of the present invention;
FIG. 4 is an enlarged view of a portion of FIG. 3 at A;
FIG. 5 is a schematic view of a separator structure according to the present invention;
FIG. 6 is a schematic view of a conical bump structure according to the present invention;
FIG. 7 is a side view of a sampling plate of the present invention;
FIG. 8 is an enlarged view of a portion of FIG. 7 at B;
FIG. 9 is a cross-sectional view of the seal cap of example 2 of the present invention;
FIG. 10 is an enlarged view of a portion of FIG. 9 at C;
fig. 11 is a schematic diagram of a latch structure in embodiment 2 of the present invention.
Wherein, the device comprises a 1-sampling tube, a 2-sealing cover, a 3-vertical rod, a 4-sampling plate, a 5-partition plate, a 6-protection bulge, a 7-liquid sac, an 8-push switch, a 9-conical bulge, a 10-liquid outlet hole, a 11-elastic telescopic rod, a 12-clamping groove, a 13-clamping block and a 14-fluff.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
As shown in fig. 1-8, this embodiment discloses a mycobacterium tuberculosis collection and pretreatment device based on tongue swab specimens, including sampling tube 1, sealed lid 2 and sampling swab, sampling tube 1 and sealed lid 2 threaded connection, sampling swab sets up at sealed lid 2's middle part, stretch into sampling tube 1, be provided with injection mechanism in the sealed lid 2, the culture solution has been stored in the injection mechanism, the culture solution can adopt 4% NaOH digestive juice or NALC-NaOH solution, sampling swab includes montant 3 and sampling plate 4, montant 3 is hollow mechanism and is linked together with injection mechanism, sampling plate 4 sets up the sampling end at montant 3.
For the fixed of convenient sample swab, be provided with baffle 5 in the middle of the inside of sampling tube 1, the middle part of baffle 5 corresponds montant 3 and is provided with the through-hole, the both sides of through-hole are provided with the transverse hole that is used for sampling plate 4 to pass through, baffle 5's setting has improved the fixed effect of sample swab in sampling tube 1, avoid sampling plate 4 and pipe wall touching, lead to the sample to remain at the pipe wall, the residual sample is difficult to be soaked by the culture solution, certain security risk has, and after the sample is stewed, the accessible rotation pull-up's mode makes baffle 5 card sampling plate 4, thereby take off sampling plate 4 from montant 3.
Specifically, the sampling plate 4 is rectangular, a connecting pipe is arranged in the middle of the sampling plate 4, a rubber anti-slip layer is arranged in the connecting pipe, the sampling plate 4 is sleeved on the vertical rod 3 through the connecting pipe, the rubber anti-slip layer is arranged to prevent the sampling plate 4 and the vertical rod 3 from easily sliding relatively, fluff 14 inclined towards the direction of the sealing cover 2 is arranged on two sides of the sampling plate 4, sampling can be carried out on two sides of the sampling plate 4 from the interior of the tongue during sampling, the sampling rate is improved, and inclined protective protrusions 6 are arranged at the top end of the sampling plate 4, so that after the sampling plate 4 passes through the partition plate 5, samples on the surface touch the partition plate 5 after the sampling plate 4 is sampled.
As a preferred embodiment of the present invention, the injection mechanism includes a liquid bag 7 and a push switch 8, the liquid bag 7 is disposed in the sealing cover 2, the liquid bag 7 in this embodiment is of an inverted corrugated flexible bottle structure, the push switch 8 is disposed at the top end of the liquid bag 7, a chute is disposed at one side of the sealing cover 2, and the push switch 8 is defined in the chute.
As a preferred embodiment of the invention, the end part of the vertical rod 3 is provided with a rubber film for sealing, the bottom end of the sampling tube 1 is provided with a conical bulge 9 corresponding to the rubber film, specifically, the top of the conical bulge 9 is hollow, and the bottom of the conical bulge 9 is provided with a liquid outlet hole 10 communicated with the top of the conical bulge 9.
The sampling swab in this embodiment is usually stored in sampling tube 1, sampling tube 1 mouth is sealed through sealed lid 2 and avoids polluting, at this moment rubber film can't touch toper protruding 9 just, the culture fluid seals in liquid bag 7, when needs sample, only need take out the sampling swab, wipe the sample from inside to outside by medical personnel from patient tongue surface, put into sampling tube 1 after the sample is accomplished, dial down push switch 8, make bottom rubber film bulge and touch toper protruding 9, rubber film is pricked, the culture fluid flows into sampling tube 1 along with the downshift of push switch 8 until submergence sampling plate 4, screw up sealed lid 2 and form sealed environment, after standing and mixing for a period, loosen sealed lid 2, push switch 8 upwards, inhale the liquid bag 7 with mixed culture fluid through cavity montant 3, upwards pull montant 3 and rotatory certain angle, available baffle 5 is taken down sample plate 4 from montant 3, make things convenient for montant 3 to pour into other test tubes with mixed culture fluid.
Example 2
As shown in fig. 9-11, the difference between this embodiment and embodiment 1 is that, in this embodiment, the inner side of the push switch 8 is connected with an elastic telescopic rod 11, the push switch 8 is installed at the end of the piston rod of the elastic telescopic rod 11, in order to lock the position of the liquid bag 7 at any time, the inner side surface of the sealing cover 2 is longitudinally and uniformly provided with a clamping groove 12, the piston rod of the ejection telescopic rod 11 is correspondingly provided with a clamping block 13, in a conventional state, the clamping block is locked in the clamping groove 12 under the push of the piston rod of the elastic telescopic rod 11, so that the liquid bag 7 cannot move, when the culture liquid needs to be pushed out, the push switch 8 is pushed inwards, the clamping block 13 is simultaneously separated from the clamping groove, and then the push switch 8 is pushed downwards, so that the culture liquid can be pushed into the sampling tube 1.
The foregoing description is only a preferred embodiment of the present invention, and is not intended to limit the technical scope of the present invention, so any minor modifications, equivalent changes and modifications made to the above embodiments according to the technical principles of the present invention still fall within the scope of the technical solutions of the present invention.
Claims (9)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411378106.5A CN119242426B (en) | 2024-09-30 | 2024-09-30 | A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411378106.5A CN119242426B (en) | 2024-09-30 | 2024-09-30 | A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN119242426A true CN119242426A (en) | 2025-01-03 |
| CN119242426B CN119242426B (en) | 2025-06-13 |
Family
ID=94031401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411378106.5A Active CN119242426B (en) | 2024-09-30 | 2024-09-30 | A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN119242426B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373689A1 (en) * | 1999-07-29 | 2001-02-08 | Thomas W. Coneys | Sampling tube holder for blood sampling system |
| CN204661698U (en) * | 2015-05-11 | 2015-09-23 | 杭州隆基生物技术有限公司 | A kind of callable Device for microorganism sample collection |
| CN208500963U (en) * | 2018-05-07 | 2019-02-15 | 李文波 | A kind of swab of sampling and pre-treatment one |
| CN221511965U (en) * | 2023-09-26 | 2024-08-13 | 予果生物科技（北京）有限公司 | A portable tongue swab sampler with bionic structure |
| CN221667284U (en) * | 2024-01-22 | 2024-09-06 | 柯柳琴 | A feces sampling device for gastroenterology |
-
2024
- 2024-09-30 CN CN202411378106.5A patent/CN119242426B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2373689A1 (en) * | 1999-07-29 | 2001-02-08 | Thomas W. Coneys | Sampling tube holder for blood sampling system |
| CN204661698U (en) * | 2015-05-11 | 2015-09-23 | 杭州隆基生物技术有限公司 | A kind of callable Device for microorganism sample collection |
| CN208500963U (en) * | 2018-05-07 | 2019-02-15 | 李文波 | A kind of swab of sampling and pre-treatment one |
| CN221511965U (en) * | 2023-09-26 | 2024-08-13 | 予果生物科技（北京）有限公司 | A portable tongue swab sampler with bionic structure |
| CN221667284U (en) * | 2024-01-22 | 2024-09-06 | 柯柳琴 | A feces sampling device for gastroenterology |
Also Published As
| Publication number | Publication date |
|---|---|
| CN119242426B (en) | 2025-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102798542A (en) | Device for stool sampling and occult blood self-detection | |
| CN207036507U (en) | Twenty-four-hour urine Protein Detection multifunctional urine collecting and sampling device | |
| CN201417224Y (en) | Medical urine collector | |
| CN205568963U (en) | Vacuum blood collection tube | |
| CN119242426B (en) | A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens | |
| CN204710574U (en) | A kind of fluid separation applications centrifuge tube | |
| CN209449556U (en) | A kind of integral type blood sampling cryopreservation tube | |
| CN203811408U (en) | Disposable excrement sample collecting treating device | |
| CN202757792U (en) | Excrement sampling and occult blood self testing device | |
| CN208043492U (en) | A kind of medicine detection sampler | |
| CN206891787U (en) | A kind of urine testing sampling device | |
| CN214422628U (en) | A new coronavirus nucleic acid detection sampling test tube | |
| CN213708352U (en) | A disposable virus sampling dropper | |
| CN203842079U (en) | Drainage bottle for cardiovascular medicine | |
| CN209286317U (en) | A kind of anti-pollution big volume BAL fluid collector | |
| CN207703551U (en) | A kind of receiving cavate urine specimen collecting bag | |
| CN209547992U (en) | Heparin tube | |
| CN202400801U (en) | Vacuum blood collecting tube opener | |
| CN206818434U (en) | A kind of clinical laboratory stool examination sampler | |
| CN105769253A (en) | Urine sample retention instrument | |
| CN217066429U (en) | Medical urine sample collection bucket | |
| CN207751774U (en) | A kind of chromatography reagent acquisition process and detection device | |
| CN209136684U (en) | A kind of twenty-four-hour urine liquid leaves and takes collection device | |
| CN220193066U (en) | Urine chemical examination sample tube | |
| CN207751707U (en) | A kind of medical sampler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |