CN1191751A - Chinese medicine Gutongning and its preparation - Google Patents
Chinese medicine Gutongning and its preparation Download PDFInfo
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- CN1191751A CN1191751A CN98112828A CN98112828A CN1191751A CN 1191751 A CN1191751 A CN 1191751A CN 98112828 A CN98112828 A CN 98112828A CN 98112828 A CN98112828 A CN 98112828A CN 1191751 A CN1191751 A CN 1191751A
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- 239000003814 drug Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000002156 mixing Methods 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 23
- 239000000843 powder Substances 0.000 claims description 22
- 210000000582 semen Anatomy 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 238000004519 manufacturing process Methods 0.000 claims description 14
- 239000003795 chemical substances by application Substances 0.000 claims description 13
- 241000411851 herbal medicine Species 0.000 claims description 13
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 11
- 241000180649 Panax notoginseng Species 0.000 claims description 11
- 239000002775 capsule Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 241000218176 Corydalis Species 0.000 claims description 8
- 239000000796 flavoring agent Substances 0.000 claims description 8
- 241001057584 Myrrha Species 0.000 claims description 7
- 239000002552 dosage form Substances 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 7
- 239000012141 concentrate Substances 0.000 claims description 6
- 239000006071 cream Substances 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- 238000005303 weighing Methods 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 5
- 239000000047 product Substances 0.000 claims description 5
- 241000283690 Bos taurus Species 0.000 claims description 4
- 238000000643 oven drying Methods 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- 229940040145 liniment Drugs 0.000 claims description 2
- 239000000865 liniment Substances 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- -1 is the 60-200 order Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 11
- 201000010099 disease Diseases 0.000 abstract description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 10
- 240000000031 Achyranthes bidentata Species 0.000 abstract 1
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 238000000227 grinding Methods 0.000 abstract 1
- 244000237330 gutta percha tree Species 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000007873 sieving Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 description 15
- 210000000988 bone and bone Anatomy 0.000 description 9
- 239000008280 blood Substances 0.000 description 8
- 206010005963 Bone formation increased Diseases 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 230000007850 degeneration Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
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- 238000010827 pathological analysis Methods 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 1
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
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- 208000008930 Low Back Pain Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
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- 239000011574 phosphorus Substances 0.000 description 1
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Abstract
The said Chinese medicine, in various preparation forms, is prepared with Fructus Psoraleae, Eucommia ulmoides, Achyranthes bidentata, peach kernel, Chinese angelica and other eight Chinese medicinal materials and through washing, stoving, crushing, lixiviation, concentration, mixing, grinding, sieving and other steps. It has obvious radical cure effect on hyperosteogency and other osteological disease and no toxic side effect. Through simultaneous internal taking and external application, it can result in determinate and stable cure effect in short period. The preparation process of the present invention is suitable for industrial production.
Description
The invention belongs to motherland's Chinese medicine and production method thereof, especially relate to a kind of GUTONGNING Chinese medicine and production method thereof.
Hyperosteogeny is the middle-aged and elderly people degeneration, people's sickness rate more than 40 years old is up to 83.6-92%, it also is one of commonly encountered diseases, still there is not specific medicament at present, though the sick medicine of multiple orthopaedics is arranged in known product or document record, in orthopaedics diseases such as treatment hyperosteogeny, play better action and effect, treatment time is long, slow deficiency takes effect but exist, these medicines are taken only by the mouth can not external, perhaps can only external application and can not take orally, the medicine that has is that lumbago is controlled waist, skelalgia is controlled lower limb, takes stopgap measures and does not effect a permanent cure, and can not reach radical cure.
The purpose of this invention is to provide a kind of GUTONGNING Chinese medicine, should be able to short, the instant effect of treatment time in orthopaedic disease such as treatment hyperosteogeny etc., can take orally and can external application, effecting a permanent cure is main, treating both the principal and secondary aspects of a disease, should be able to reach radical cure to orthopaedic diseases such as hyperosteogenys.
Another object of the present invention provides a kind of production method of GUTONGNING Chinese medicine, should be able to be easy to the GUTONGNING Chinese medicine of the multiple dosage form of industrialized Development and Production.
The objective of the invention is to adopt following technical proposals to realize: 1, a kind of GUTONGNING Chinese medicine is characterized in that comprising component:
Fructus Psoraleae 2-30% Cortex Eucommiae 2-30% river cattle sunset 2-30% Semen Persicae 2-20% Radix Angelicae Sinensis 2-30%
Caulis Spatholobi 2-30% Rhizoma Chuanxiong 2-20% Herba speranskiae tuberculatae 2-30% Herba Asari 2-20% Radix Notoginseng 1-20%
Rhizoma Corydalis 2-30% sends out medicine 2-20% Semen Strychni 1-20%
Above-mentioned each Chinese medicinal components gross weight is the production method of a hundred per cent 2, a kind of GUTONGNING Chinese medicine, it is characterized in that comprising following production method;
(1), cleans: earlier with the Cortex Eucommiae, river Niu Xi, Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba speranskiae tuberculatae, Herba Asari, Myrrha
This eight herbal medicine is cleaned, is dried;
(2), the oven dry: air dried eight herbal medicines are put into drying room, temperature control 40-60 ℃ oven drying at low temperature 3-6 hour;
(3), pulverize: will dry the eight herbal medicines weighing by weight respectively of postcooling, and send pulverizer to room temperature
It is stand-by to mix the pulverizing back;
(4), leach: Fructus Psoraleae, Caulis Spatholobi, Rhizoma Corydalis three herbal medicines respectively by weight weighing, are put into
Decoction pot decocting in water twice, add the water of water 5-8 times weight the first time, decocted 2-3 hour,
Leach medicinal liquid, add the water of water 4-6 times weight for the second time, decocted 1.5-2.5 hour, again
The inferior medicinal liquid that leaches;
(5), concentrate: the medicinal liquid of twice decoction is mixed, decocted again 0.5-1.5 hour, become to concentrate
The medicinal liquid of state;
(6), mix: pour spissated medicinal liquid and the eight flavor medicated powder that crush into the blender mixing and stirring:
(7), oven dry: put into oven for drying again, temperature control 50-70 ℃, water content is in 10%;
(8), in small, broken bits: pulverizing again, the 60-200 mesh sieve is stand-by excessively;
(9), mix: with Semen Strychni make the moxibustion Semen Strychni Pulveratum, Radix Notoginseng is made Radix Notoginseng powder, is the 60-200 order,
Mix with the meticulous powder of above-mentioned ten Herba indigoferae Pseudotinctoriae again, make GUTONGNING Chinese medicine of the present invention and loose
Powder;
(10), dress capsule: the loose powder agent is incapsulated, make capsule;
(11), other dosage forms: the agent of GUTONGNING Chinese medicine loose powder adds shape-fixing agent film-making granule type, adds filler
System cream pill-type adds baste and makes oral liquid.
The beneficial effect that the present invention is compared with prior art had;
1, from technical scheme traditional Chinese medical science pathological analysis of the present invention:
Motherland's medical science think hyperosteogeny be old suffer from a deficiency of the kidney relevant with bone degeneration, kidney is behaved the beginning originally, kidney storing essence, the main again bone of kidney is given birth to marrow, kidney governing storage, kidney essense benefit is hidden not beneficial letting out, so " interior warp, the big opinion of YIN YANG classification of natural phenomena ", " interior warp, nephropathy visceral relationship by " are said " kidney producing bone marrow ", " people crosses 40 kidney qis and declines ".Because old suffering from a deficiency of the kidney gradually lost the function that its main bone is given birth to marrow, causes a little less than the atrophic debility of bones muscle bone degeneration.Modern medicine study proves that the autacoid of kidney has regulating action to calcium, phosphorus metabolism process, when the human body deficiency of kidney-QI, healthy energy must be empty, and battalion defends imbalance, interspaces of skin and muscles being loose, exopathogen invading the interior, so the heresy that susceptible wind and cold is wet, hinder the gas of Yuanyang again, wound can cause coagulation of QI-blood in channels, impatency is not smooth, the bone mistake is moistened foster, and labor of a specified duration etc. also can cause kidney to be hindered, and kidney is hindered also can cause bone degeneration.According to motherland's theory of medicine, the present invention lays particular emphasis on invigorating the liver and kidney, strengthening bone and muscle, warm smart blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, wind-damp dispelling cold expelling, the numbness that disappears pain relieving, the aseptic inflammation that makes outgrowth bony spur thing stimulate surrounding soft tissue to cause disappears rapidly, repair the articular cartilage face of wearing and tearing, the bony spur that has formed is dwindled or stop development.Like this to effect a permanent cure treating both the principal and secondary aspects of a disease, the purpose that reaches radical cure and be difficult for recurring.
2, from technical solution of the present invention traditional Chinese medical science pharmacology analysis-by-synthesis:
According to traditional Chinese medical science pathological analysis, through to plurality of Chinese component screening, analysis, trial-production and clinical and experimental study, proposed to select for use 13 flavor natural Chinese medicine plants such as Fructus Psoraleae, process.The pharmacology analysis-by-synthesis; Be with Fructus Psoraleae, the Cortex Eucommiae, river Niu Xiwei " monarch ", invigorating the liver and kidney, bone and muscle strengthening, strong waist knee joint, the same usefulness of three flavor Chinese medicines, the efficiency of drugs of can mutually promoting." minister " with Caulis Spatholobi, Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Corydalis, blood circulation promoting and blood stasis dispelling, eliminating blood stasis to promote regeneration of blood, collateral dredging stopping numbness pain." assistant " with Herba speranskiae tuberculatae, Herba Asari, wind-damp dispelling cold expelling, relaxing muscles and tendons and activating QI and blood in the collateral." make " with Myrrha, Radix Notoginseng powder, moxibustion Semen Strychni three flavors and share, can go into the twelve regular channels, should lead to internal organs meridians, removing blood stasis and activating blood flow, subduing swelling and relieving pain.
More than all medicines " monarch " synergism, supplement and complement each other, play invigorating the liver and kidney, bone and muscle strengthening jointly, the collateral dredging blood circulation promoting and blood stasis dispelling, arthralgia pain disappears.To orthopaedic diseases such as hyperosteogenys tangible permanent curing action can be arranged, no matter which kind of dosage form this medicine is, all have no side effect, but i.e. oral administration external application again simultaneously, Chinese medicine, it is main effecting a permanent cure, treating both the principal and secondary aspects of a disease, drug effect is fast, short treating period, determined curative effect and stablize.
3, the selected Chinese medicinal components of technical solution of the present invention is common Chinese herbal medicine, and cost is low, the finished product price is low, and the patient easily bears.Product forms can have capsule, loose powder agent, sheet granule type, cream pill, oral liquid, external application different dosage form such as to smear, the doctor is clinical select for use or the patient to abide by doctor's Orally taken and externally all very convenient.
4, according to clinical trial analysis:
800 many cases patients' treatment is observed in clinical trial, and 20 days is a course of treatment, and diseases such as human body osteoarthritis, hyperosteogeny, prolapse of intervertebral disc, soft tissue injury, tenosynovitis are had tangible curative effect, and total obvious effective rate reaches 98%, and no longer recurrence, obtains radical cure.Use the patient of other similar Chinese and western drugs DeGrain clinically, still can obtain tangible curative effect after using this medicine instead.
5, the GUTONGNING Chinese medicine production method that provides of the present invention, suitability for industrialized production is easy in batch.
Technical scheme of the present invention in sum can obtain beneficial effect preferably.
Further describe technical solution of the present invention: embodiment 1 in conjunction with the embodiments:
A kind of GUTONGNING Chinese medicine, the percentage by weight of each Chinese medicinal components optimum content is:
Fructus Psoraleae 13% Cortex Eucommiae 11% river cattle sunset, 11% Semen Persicae, 7% Radix Angelicae Sinensis 8%
Caulis Spatholobi 11% Rhizoma Chuanxiong 5% Herba speranskiae tuberculatae 8% Herba Asari 4% Radix Notoginseng 4%
Rhizoma Corydalis 11% Myrrha 5% Semen Strychni 3% also can comprise excipient, filler,
Flavoring agent.
Product forms can be capsule, loose powder agent, sheet granule, cream pill, liquid oral liquid or external application liniment.Embodiment 2:
A kind of production method of GUTONGNING Chinese medicine comprises following production method;
(1), cleans: earlier with the Cortex Eucommiae, river Niu Xi, Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba speranskiae tuberculatae, Herba Asari, Myrrha
This eight herbal medicine is cleaned, is dried;
(2), the oven dry: air dried eight herbal medicines are put into drying room, temperature control 40-60 ℃ oven drying at low temperature 3-6 hour;
(3), pulverize: will dry the eight herbal medicines weighing by weight respectively of postcooling, and send pulverizer to room temperature
It is stand-by to mix the pulverizing back;
(4), leach: Fructus Psoraleae, Caulis Spatholobi, Rhizoma Corydalis three herbal medicines respectively by weight weighing, are put into
Decoction pot decocting in water twice, add the water of water 5-8 times weight the first time, decocted 2-3 hour,
Leach medicinal liquid, add the water of water 4-6 times weight for the second time, decocted 1.5-2.5 hour, again
The inferior medicinal liquid that leaches;
(5), concentrate: the medicinal liquid of twice decoction is mixed, decocted again 0.5-1.5 hour, become to concentrate
The medicinal liquid of state;
(6), mix: pour spissated medicinal liquid and the eight flavor medicated powder that crush into the blender mixing and stirring:
(7), oven dry: put into oven for drying again, temperature control 50-70 ℃, water content is in 10%; (8), in small, broken bits: pulverizing again, the 60-200 mesh sieve is stand-by excessively; (9), mix: with Semen Strychni make the moxibustion Semen Strychni Pulveratum, Radix Notoginseng is made Radix Notoginseng powder, is the 60-200 order,
Mix with the meticulous powder of above-mentioned ten Herba indigoferae Pseudotinctoriae again, make GUTONGNING Chinese medicine of the present invention and loose
Powder or fine grained agent; (10), dress capsule: loose powder agent or granule are incapsulated, make capsule; (11), other dosage forms: the agent of GUTONGNING Chinese medicine loose powder adds shape-fixing agent, send pelleter film-making, granule type,
Add filler system cream pill-type, add baste and make oral liquid.Can produce each
Plant the Chinese patent medicine of dosage form.
Claims (4)
1, a kind of GUTONGNING Chinese medicine is characterized in that comprising component: Fructus Psoraleae 2-30% Cortex Eucommiae 2-30% river cattle sunset 2-30% Semen Persicae 2-20% Radix Angelicae Sinensis 2-30% Caulis Spatholobi 2-30% Rhizoma Chuanxiong 2-20% Herba speranskiae tuberculatae 2-30% Herba Asari 2-20% Radix Notoginseng 1-20% Rhizoma Corydalis 2-30% Myrrha 2-20% Semen Strychni 1-20%
Above-mentioned each Chinese medicinal components gross weight is absolutely.
2. a kind of GUTONGNING Chinese medicine according to claim 1 is characterized in that the percentage by weight of each Chinese medicinal components optimum content is: Fructus Psoraleae 13% Cortex Eucommiae 11% river cattle sunset, 11% Semen Persicae, 7% Radix Angelicae Sinensis 8% Caulis Spatholobi 11% Rhizoma Chuanxiong 5% Herba speranskiae tuberculatae 8% Herba Asari 4% Radix Notoginseng 4% Rhizoma Corydalis 11% Myrrha 5% Semen Strychni 3%
3, a kind of GUTONGNING Chinese medicine according to claim 1 is characterized in that: also comprise excipient, filler, flavoring agent, product forms can be capsule, loose powder agent, sheet granule, cream pill, liquid oral liquid or external application liniment
4, a kind of production method of GUTONGNING Chinese medicine is characterized in that comprising following production method;
(1), cleans: earlier with the Cortex Eucommiae, river Niu Xi, Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Herba speranskiae tuberculatae, Herba Asari, Myrrha
This eight herbal medicine is cleaned, is dried;
(2), dry by the fire in: air dried eight herbal medicines are put into drying room, temperature control 40-60 ℃ oven drying at low temperature 3-6 hour;
(3), pulverize: will dry the eight herbal medicines weighing by weight respectively of postcooling, and send pulverizer to room temperature
It is stand-by to mix the pulverizing back;
(4), leach: Fructus Psoraleae, Caulis Spatholobi, Rhizoma Corydalis three herbal medicines respectively by weight weighing, are put into
Decoction pot decocting in water twice, add the water of water 5-8 times weight the first time, decocted 2-3 hour,
Leach medicinal liquid, add the water of water 4-6 times weight for the second time, decocted 1.5-2.5 hour, again
The inferior medicinal liquid that leaches;
(5), concentrate: the medicinal liquid of twice decoction is mixed, decocted again 0.5-1.5 hour, become to concentrate
The medicinal liquid of state;
(6), mix: pour spissated medicinal liquid and the eight flavor medicated powder that crush into the blender mixing and stirring:
(7), oven dry: put into oven for drying again, temperature control 50-70 ℃, water content is in 10%;
(8), in small, broken bits: pulverizing again, the 60-200 mesh sieve is stand-by excessively;
(9), mix: with Semen Strychni make the moxibustion Semen Strychni Pulveratum, Radix Notoginseng is made Radix Notoginseng powder, is the 60-200 order,
Mix with the meticulous powder of above-mentioned ten Herba indigoferae Pseudotinctoriae again, make GUTONGNING Chinese medicine of the present invention and loose
Powder;
(10), dress capsule: the loose powder agent is incapsulated, make capsule;
(11), other dosage forms: the agent of GUTONGNING Chinese medicine loose powder adds shape-fixing agent film-making granule type, adds filler
System cream pill-type adds baste and makes oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98112828A CN1059594C (en) | 1998-03-08 | 1998-03-08 | Chinese medicine Gutongning and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98112828A CN1059594C (en) | 1998-03-08 | 1998-03-08 | Chinese medicine Gutongning and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1191751A true CN1191751A (en) | 1998-09-02 |
| CN1059594C CN1059594C (en) | 2000-12-20 |
Family
ID=5222623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98112828A Expired - Fee Related CN1059594C (en) | 1998-03-08 | 1998-03-08 | Chinese medicine Gutongning and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1059594C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319320A (en) * | 2011-09-23 | 2012-01-18 | 于刚 | Medicament for treating osteopathy |
| CN103638332A (en) * | 2013-11-20 | 2014-03-19 | 代永臣 | Medicinal liquor for treating Bi syndromes, and preparation method thereof |
| CN105031098A (en) * | 2015-09-13 | 2015-11-11 | 肖荣叶 | Chinese medicine composition for treating ganglion and preparation method thereof |
| CN106421690A (en) * | 2016-09-19 | 2017-02-22 | 杨佩义 | External drug formula for eliminating ostealgia |
| CN107362229A (en) * | 2017-08-18 | 2017-11-21 | 成都风靡生物科技有限公司 | It is a kind of to be used to treat Chinese medicine composition of ostalgia and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1053584C (en) * | 1996-02-09 | 2000-06-21 | 李毅 | Capsule for treating pain or numbness and preparing process thereof |
-
1998
- 1998-03-08 CN CN98112828A patent/CN1059594C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319320A (en) * | 2011-09-23 | 2012-01-18 | 于刚 | Medicament for treating osteopathy |
| CN103638332A (en) * | 2013-11-20 | 2014-03-19 | 代永臣 | Medicinal liquor for treating Bi syndromes, and preparation method thereof |
| CN105031098A (en) * | 2015-09-13 | 2015-11-11 | 肖荣叶 | Chinese medicine composition for treating ganglion and preparation method thereof |
| CN106421690A (en) * | 2016-09-19 | 2017-02-22 | 杨佩义 | External drug formula for eliminating ostealgia |
| CN107362229A (en) * | 2017-08-18 | 2017-11-21 | 成都风靡生物科技有限公司 | It is a kind of to be used to treat Chinese medicine composition of ostalgia and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1059594C (en) | 2000-12-20 |
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