Pen-holding type electric rotating solid tumor cytology puncture biopsy device
Technical Field
The invention belongs to the technical field of solid tumor cytology puncture biopsy, and particularly relates to a pen-holding type electric rotating solid tumor cytology puncture biopsy device with a negative pressure function.
Background
Solid tumors are the most common clinical tumors, and for example, thyroid tumors are one of the most rapidly growing solid malignant tumors in recent 20 years, and the incidence rate of the solid malignant tumors accounts for 3.1% of all malignant tumors, and the annual average growth rate is as high as 6.2%. The incidence rate of thyroid nodules found by ultrasonic examination is reported to be between 19 and 68 percent in literature, and China is a large population country, which means that about 2.3 to 8.8 hundred million people in China face the problem of thyroid nodules. The incidence and mortality of the thyroid cancer in China respectively account for 16.71 percent and 15.88 percent of the world, and are the countries with the highest incidence and mortality of the thyroid cancer worldwide. Research data show that if thyroid cancer can be accurately diagnosed and treated in early stage, the survival rate can reach 84.3 percent. Therefore, it is particularly important to accurately judge the nature of thyroid nodules, which not only reduces unnecessary surgical treatment and medical costs, but also reduces the risk of complications caused by excessive treatment.
Cytological biopsy is an important method for preoperative diagnosis, particularly thyroid Fine Needle Aspiration Biopsy (FNAB) is a gold standard for preoperative diagnosis, and is incorporated into domestic and foreign thyroid nodule diagnosis and treatment guidelines for thyroid cancer. The FNAB is specifically operated by placing the needle tip around or in the nodule under the guidance of ultrasound, repeatedly extracting and inserting at different angles to obtain a small amount of cell components, then performing cytological smear, and judging the benign and malignant thyroid nodule according to pathological results. FNAB is divided into two modes, namely non-negative pressure and negative pressure, and the difference between the two modes is mainly on the operation method. The operation method of the non-negative pressure fine needle puncture is that after the puncture needle core is pulled out, the cell specimen is directly sucked through the capillary siphon action of the fine needle, and the method can effectively reduce bleeding and reduce the damage of puncture to thyroid tissues. However, for some nodes having high hardness, such as those represented by fibrosis, capillary siphoning by non-negative pressure fine needle penetration is weak, and thus a negative pressure fine needle penetration method is required. The operation method of the negative pressure fine needle puncture is that after the puncture needle core is pulled out, the tail part is connected with a syringe needle cylinder, an operator repeatedly lifts and inserts the fine needle in a negative pressure state, and the negative pressure is relieved when the needle is pulled out, so that the cell quantity collected by the method is more, and the positive rate of pathological diagnosis is higher.
In the aspiration biopsy operation, a doctor needs to take ultrasound with the left hand and take a puncture needle with the right hand, and the optimal puncture point of the target spot and the epidermis is found out according to an ultrasound image and actual operation experience, so that manual puncture is performed. However, in clinical practice, it is difficult to control the negative pressure by pulling the syringe core bar only by the right hand, and the clinical experience of the doctor is required to be high. Meanwhile, in clinical practice, some tough nodules tend to move in the same direction as the needle during the puncturing process, which can reduce sampling success rate.
Disclosure of Invention
In view of this, the present invention is directed to designing a novel pen-held electric rotating solid tumor cytology biopsy device that innovatively integrates the forward and backward rotation, forward and backward expansion and retraction functions, and automatic negative pressure or controllable negative pressure functions of a puncture needle, so as to improve the operability and sampling success rate of the puncture device.
In order to achieve the above purpose, the technical scheme of the invention is realized as follows:
a pen-holding type electric rotating solid tumor cytology puncture biopsy device comprises a puncture needle, a shell, a rotating/front-back telescopic module and a negative pressure module which are arranged in the shell, and a puncture needle arranged at the end part of the shell;
the rotary/front-rear telescopic module comprises a first driving motor, a driving gear, a driven gear, a first end face cam and a second end face cam, wherein the first end face cam and the second end face cam can rotate relatively and reset axially;
the negative pressure module comprises a syringe and a driving assembly for driving a core rod of the syringe to reciprocate, and the syringe is communicated with the puncture needle through a liquid channel arranged in the second end face cam and a liquid channel arranged in the first end face cam in sequence. Core bar
Furthermore, the head of the first end face cam and the head of the second end face cam are respectively provided with a concave part and a convex part, and the concave part and the convex part of the first end face cam are alternately contacted with the concave part and the convex part of the second end face cam in the rotating process to realize the back-and-forth reciprocating motion of the puncture needle.
Further, a reset spring is arranged between the driven gear and the first end face cam, and a sealing ring is arranged between the first end face cam and the second end face cam.
Further, two guide keys are arranged on the first end face cam, and two long key grooves matched with the guide keys are arranged on the corresponding positions of the driven gear.
Further, a conical hole is formed in the tail end face of the second end face cam, and a liquid outlet of the injector is arranged in the conical hole.
Further, the driven gear is provided with a first bearing and a second bearing in an interference fit, and the first bearing and an outer ring of the second bearing are arranged in the shell in an interference fit.
Further, the driving assembly comprises a second driving motor, a ball screw nut and a push block, wherein the ball screw is connected with an output shaft of the second driving motor, the ball screw nut is arranged on the ball screw, the push block is connected with the ball screw nut, and the push block is connected with a core rod of the injector to drive the core rod of the injector to reciprocate in a straight line.
Further, a third bearing and a fourth bearing are respectively arranged at two ends of the ball screw, inner rings of the third bearing and the fourth bearing are respectively arranged at the end part of the ball screw in an interference fit mode, and outer rings of the third bearing and the fourth bearing are arranged on the shell in an interference fit mode.
Further, the driving assembly comprises a poking roller and a displacement supporting rod which are meshed with each other, the poking roller stretches out of the surface of the shell, one end of the displacement supporting rod is connected with a core rod of the injector, and the poking roller is rotated to drive the displacement supporting rod to slide so as to drive the core rod of the injector to reciprocate in a linear mode.
Further, the puncture device further comprises a control module and a power module, the control module is electrically connected with the power module, the first driving motor is electrically connected with the control module, a self-resetting button is arranged on the shell, and the self-resetting button is electrically connected with the control module and used for controlling the first driving motor.
The second driving motor is respectively and electrically connected with the control module and the power supply module.
Further, the second driving motor is electrically connected with the control module, a gear adjusting sliding switch is arranged on the shell, and the gear adjusting sliding switch is electrically connected with the control module and used for controlling the second driving motor.
Further, the second end cam is fixed in the shell through two positioning blocks arranged on the side face.
Further, the first driving motor and the second driving motor are both fixed in the shell.
Further, the outer ring of the first bearing and the outer ring of the second bearing are all installed in the shell in an interference fit mode.
Compared with the prior art, the invention has the following advantages:
(1) The puncture needle of the pen-holding type electric rotating solid tumor cytology puncture biopsy device has the function of forward and backward stretching while rotating forward and backward, and changes the traditional manual lifting and inserting cutting mode into a cutting mode of coupling forward and backward stretching under the drive of a motor, so that the suction and inserting action and the puncture distance in the puncture process are ensured, the automatic or controllable negative pressure is realized, the experience dependence of an operator puncture technology is obviously reduced, the learning curve of the operator is effectively shortened, the effective rate of sample acquisition is improved, and the possibility of complications possibly generated in the puncture process can be obviously reduced.
(2) The pen-holding type electric rotating solid tumor cytology puncture biopsy device is internally provided with the automatic or controllable negative pressure module for sucking, so that the cell tissues can be collected more effectively, the success rate of sample acquisition is greatly improved, the puncture efficiency is improved, repeated punctures are avoided, the burden of doctors and patients is reduced, and the incidence rate of needle tract tumor implantation caused by repeated manual lifting and insertion is reduced. Simultaneously, adopt automatic or controllable negative pressure module to compare in manual pull core bar more portably and accurately, use gear to adjust slide switch or stir the gyro wheel and can control the negative pressure size, the design of a plurality of gears in the gear adjustment slide switch and the design of stirring the gyro wheel can satisfy the user demand of different circumstances.
(3) The shell of the pen-holding type electric rotating solid tumor cytology puncture biopsy device disclosed by the invention adopts a streamline design which accords with human engineering, is good in handheld stability, and is not easy to shake in the puncture and suction processes.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention. In the drawings:
FIG. 1 is a schematic view of the overall appearance of example 1;
FIG. 2 is a schematic view of the overall appearance of example 1, FIG. 2;
FIG. 3 is a schematic view of the housing of example 1;
FIG. 4 is a schematic overall structure of embodiment 1;
FIG. 5 is a schematic view of the rotary/front-to-back telescoping module of example 1;
fig. 6 is a cross-sectional view of the rotary/front-rear expansion module of embodiment 1;
FIG. 7 is a schematic diagram of the movement of the face cam mechanism in the rotary/front-rear expansion module of embodiment 1;
FIG. 8 is a schematic view of a negative pressure module of example 1;
fig. 9 is a schematic overall appearance of embodiment 2;
FIG. 10 is a cross-sectional view of the puncture device of example 2.
Reference numerals illustrate:
1. A housing; 2. a rotation/fore-aft telescoping module; 3. an automatic negative pressure module; 4. a puncture needle; 5. a self-resetting button; 6. a gear adjusting slide switch; 7. a left housing; 8. a right housing; 9. a first driving motor; 10. a drive gear; 11. a driven gear; 12. a first bearing; 13. a second bearing; 14. a first end face cam; 15. a second end cam; 16. a conversion joint; 17. a second driving motor; 18. a syringe; 19. a ball screw; 20. a ball screw nut; 21. a third bearing; 22. a fourth bearing; 23. a pushing block; 24. a spring; 25. a seal ring; 26. the roller is stirred; 27. and (5) displacing the supporting rod.
Detailed Description
It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art in a specific case.
The invention will be described in detail below with reference to the drawings in connection with embodiments.
Example 1
Referring to fig. 1 to 8, the invention provides a pen-holding type electric rotating solid tumor cytology puncture biopsy device, which specifically comprises a shell 1, a rotating/front-back telescopic module 2, a negative pressure module 3, a puncture needle 4, a self-resetting button 5, a gear adjusting sliding switch 6, a control module (not shown in the figure) and a power supply module (not shown in the figure).
Referring to fig. 1 to 4, the housing 1 includes a left housing 7 and a right housing 8, and the left housing 7 and the right housing 8 are connected by self-tapping screws. The shell 1 adopts a streamline design conforming to the ergonomics, such as an ergonomic groove (not shown in the figure) for placing fingers is arranged on the shell 1, so that the hand-held stability is good, shaking is not easy to occur in the process of puncturing and sucking, and the comfort of user operation is facilitated.
Boss clamping grooves are formed in the left shell 7 and the right shell. The inside of casing 1 is the installation cavity, and rotatory/flexible module 2 around and negative pressure module 3 are all installed in the installation cavity, and gear adjustment slide switch 6 is installed in the boss draw-in groove of left casing 7, fixes at the surface of left casing 7 through the screw connection, installs in the boss draw-in groove of right casing 8 from reset button 5 to the form of bolted connection is fixed at the surface of right casing 8.
Referring to fig. 4 to 6, the rotation/front-rear expansion module 2 includes a first driving motor 9, a driving gear 10, a driven gear 11, a first bearing 12, a second bearing 13, a first end cam 14, a second end cam 15, an adapter 16, a spring 24, and a seal ring 25. The first drive motor 9 is fixed to the housing 1 by a saddle clamp. The D-shaped output shaft of the first driving motor 9 is in interference fit connection with the D-shaped hole of the driving gear 10, and the driving gear 10 is meshed with the driven gear 11 for transmission. The first bearing 12 and the inner ring of the second bearing 13 are in interference fit on the driven gear 11, and the first bearing 12 and the outer ring of the second bearing 13 are in interference fit on the shell 1 so as to improve the rotation coaxiality of the driven gear 11.
Specifically, the first end cam 14 is provided with two guide keys (not shown), and the driven gear 11 is provided with two long key grooves (not shown) at corresponding positions, so that the first end cam 14 is slidably connected to the driven gear 11. The long key groove of the driven gear 11 enables the first end cam 14 to realize radial and circumferential positioning and fixing, so that the first end cam 14 can rotate along with the driven gear 11; meanwhile, the axial degree of freedom of the first end cam 14 is not limited, so it can still move back and forth in the axial direction of the driven gear 11.
Referring to fig. 4 and 5, the second end cam 15 is directly fixed to the housing 1 by two positioning blocks on the side. Referring to fig. 6 and 7, since the driven gear 11 may drive the first end cam 14 to rotate and the second end cam 15 is directly fixed on the housing 1, the head of the first end cam 14 and the head of the second end cam 15 are respectively provided with a concave portion and a convex portion, and the concave portion and the convex portion of the first end cam 14 are alternately contacted with the concave portion and the convex portion of the second end cam 15 during rotation, the first end cam 14 and the second end cam 15 may be misaligned and aligned. When the misalignment occurs, the puncture needle 4 moves forward; when the alignment phenomenon occurs, the puncture needle 4 moves backward, and finally, the back and forth reciprocating rotational movement of the puncture needle 4 is realized. Because the resistance of the soft tissues contacted with the puncture needle 4 is different, if the soft tissues are knotted around the puncture needle 4 due to forward and backward rotation, the needle tip and the needle tail are not coaxial, and finally the puncture needle 4 cannot be pulled out, the puncture needle 4 can avoid the problems by adopting the same-direction rotation of the puncture needle 4, in addition, the motor is used for controlling the rotation/forward and backward telescopic module to realize larger forward and backward telescopic action force, the synchronous movement of the puncture needle 4 and the tissues around the puncture needle can be effectively avoided, the cutting effect is improved, and the sucking efficiency is improved.
Specifically, when the driven gear 11 drives the first end cam 14 to rotate, the concave portion of the first end cam 14 is engaged with the convex portion of the second end cam 15, the convex portion of the first end cam 14 is engaged with the concave portion of the second end cam 15 under the action of the spring 24, the first end cam 51 is in a close engagement with the second end cam 52, the puncture needle 4 moves backward at this time, the driven gear 11 drives the first end cam 14 to continue to rotate, and the first end cam 14 rotates until the convex portion thereof contacts with the convex portion of the second end cam 52, and the puncture needle 4 moves forward at this time.
In order to ensure the tightness of the device, as shown in fig. 6, the driven gear 11 is a seal sleeve and gear integrated structure. The spring 24 is installed between the driven gear 11 and the first end cam 14 to restore the first end cam 14 each time the misalignment occurs. The sealing ring 25 is installed between the first end cam 14 and the second end cam 15 to ensure that liquid cannot leak and be sealed.
The first end cam 14 is removably connected to the adapter 16 by conventional threads, and the adapter 16 is removably connected to the needle 4 by luer threads. The tail part of the second end cam 15 is provided with a conical hole, and is connected with the negative pressure module 3 through interference fit.
The first end cam 14 and the second end cam 15 are hollow in the axial direction and serve as liquid channels, and the injector 18 is communicated with the puncture needle 4 through the liquid channels arranged inside the second end cam 15 and the first end cam 14 in sequence. In the biopsy puncture process, under the action of the negative pressure module 3, liquid sequentially passes through the puncture needle 4, the first end cam 14 and the liquid channel of the second end cam 15 and enters the injector 18 to successfully suck the cell specimen.
Referring to fig. 8, the negative pressure module 3 includes a second driving motor 17, a syringe 18, and a driving assembly for driving the plunger of the syringe to reciprocate, the driving assembly including a ball screw 19, a ball screw nut 20, a third bearing 21, a fourth bearing 22, and a push block 23. The second drive motor 17 is fixed to the housing 1 by a set screw. The ball screw 19 is provided with a D-shaped hole and is connected with a D-shaped output shaft of the second driving motor 17, the inner rings of the third bearing 21 and the fourth bearing 22 are installed on the ball screw 19 in an interference fit manner, and the outer rings of the third bearing 21 and the fourth bearing 22 are installed on the shell 1 in an interference fit manner so as to ensure the normal operation of the ball screw 19. The ball screw nut 20 is mounted on the ball screw 19, the ball screw 19 rotates to drive the ball screw nut 20 to move, and the track is arranged on the shell 1 to ensure that the ball screw nut 20 moves linearly. The push block 23 is connected with the ball screw nut 20 through a bolt, and a circular baffle plate at the tail end of the core rod of the injector 18 is arranged between an extending arm arranged on the push block 23 and the semicircular baffle plate, and the push block 23 drives the core rod of the injector 18 to reciprocate linearly. The front end of the injector 18 is connected with the second end cam 15 in the rotary-front-rear telescopic module 2 by interference fit.
The first driving motor 9 is respectively and electrically connected with the control module and the power module through cables, and the self-resetting button 5 arranged on the shell 1 is electrically connected with the control module to control the first driving motor 9 so as to control the rotation/front-back stretching function of the puncture needle 4. The second driving motor 17 is electrically connected with the control module and the power module through cables respectively, and the gear adjusting sliding switch 6 arranged on the shell 1 is electrically connected with the control module to control the second driving motor 17 to control the negative pressure module.
When the puncture needle is used, the power supply module is started to supply power for the puncture device, the puncture needle 4 is arranged around or in a nodule, the self-reset button 5 is pressed to start the rotation/front-back expansion module 2, meanwhile, the lowest gear of the gear adjusting sliding switch 6 is started to pull out the core rod of the syringe to enable certain negative pressure to be generated in the syringe, at the moment, the puncture needle 4 rotates in the same direction and simultaneously expands back and forth to absorb a cell specimen, if a nodule with higher part of hardness is encountered, the gear of the adjustable high-gear adjusting sliding switch 6 increases the negative pressure in the syringe until enough cell specimen is absorbed, the self-reset button 5 and the gear adjusting sliding switch 6 are closed, and the puncture needle 4 is pulled out to finish the puncture biopsy operation.
Example 2
Referring to fig. 9 to 10, the difference from embodiment 1 is that:
The negative pressure module comprises an injector and a driving component for driving the core rod of the injector 18 to reciprocate, wherein the driving component comprises a poking roller 26 and a displacement supporting rod 27 which are meshed with each other, the poking roller 26 stretches out of the surface of the shell 1, one end of the displacement supporting rod 27 is connected with the core rod of the injector 18, the poking roller 26 is rotated to drive the displacement supporting rod 27 to slide so as to drive the core rod of the injector 18 to reciprocate in a linear manner, and a structure for preventing the fluctuation roller from automatically resetting in the use process is further arranged in the driving component, and is a well-known technology in the field and is not repeated herein.
When the puncture needle is used, the power supply module is started to supply power for the puncture device, the puncture needle 4 is arranged around or in a nodule, the self-reset button 5 is pressed to start the rotation/front-back expansion module 2, meanwhile, the poking roller 26 is rotated by a certain angle to enable the displacement support rod to drive the core rod of the injector to be pulled out, so that certain negative pressure is generated in the injector, the puncture needle 4 is enabled to rotate in the same direction and simultaneously expand and draw a cell specimen forwards and backwards, if a nodule with higher part of hardness is encountered, the angle poking roller 26 can be further rotated to increase the negative pressure in the injector until enough cell specimen is drawn, the self-reset button 5 is closed, and the puncture biopsy operation is completed after the puncture needle 4 is pulled out.
The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.