CN118948341A - Methods for collecting cerebrospinal fluid information in medical clinics - Google Patents
Methods for collecting cerebrospinal fluid information in medical clinics Download PDFInfo
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- CN118948341A CN118948341A CN202411055682.6A CN202411055682A CN118948341A CN 118948341 A CN118948341 A CN 118948341A CN 202411055682 A CN202411055682 A CN 202411055682A CN 118948341 A CN118948341 A CN 118948341A
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Abstract
本发明涉及一种医疗临床脑脊液信息采集方法，其包括如下步骤：第一步、将取液管穿刺插入人体中，使该取液管的前端浸入到人体蛛网膜下腔内的脑脊液中，该取液管包括管体、穿刺部分以及侧向取液口，第二步、利用该取液管抽取脑脊液，在该取液管中得到定量脑脊液,第三步、将该取液管整体从人体上移除，该定量脑脊液封存在该取液管中，第四步、将该取液管转换为脑脊液释出状态，第五步、将该取液管中的该定量脑脊液定量释出进行脑脊液的信息采集。
The present invention relates to a medical clinical cerebrospinal fluid information collection method, which comprises the following steps: a first step, inserting a liquid collection tube into a human body by puncturing, so that the front end of the liquid collection tube is immersed in the cerebrospinal fluid in the subarachnoid cavity of the human body, the liquid collection tube comprising a tube body, a puncture part and a lateral liquid collection port; a second step, extracting cerebrospinal fluid by using the liquid collection tube, and obtaining quantitative cerebrospinal fluid in the liquid collection tube; a third step, removing the liquid collection tube as a whole from the human body, and the quantitative cerebrospinal fluid is sealed in the liquid collection tube; a fourth step, converting the liquid collection tube into a cerebrospinal fluid release state; and a fifth step, quantitatively releasing the quantitative cerebrospinal fluid in the liquid collection tube to collect cerebrospinal fluid information.
Description
Technical Field
The invention relates to a spinal fluid information acquisition method, in particular to a method for acquiring cerebrospinal fluid information in medical clinic.
Background
Cerebrospinal fluid is a clear, colorless fluid that is secreted primarily by the ventricles of the brain and by the choroid plexus in the pial space of the spinal cord, and passes through the ventricles of the brain into the subarachnoid space, where it then flows in the cerebrospinal fluid circulation pathway.
Cerebrospinal fluid has a variety of important roles in the central nervous system of the human body, for example, it can be a cushion for the brain and spinal cord, alleviating damage to the central nervous system by external impact, and also maintaining the health of the nervous tissue and ensuring normal function of nerve cells by transporting nutrients and removing metabolic waste.
When the central nervous system is affected by a disease, such as bacterial infection, inflammation, hemorrhage, etc., the pathological changes may leave marks in the cerebrospinal fluid, so that the cerebrospinal fluid may reflect the pathological changes in the central nervous system, and taking a sample of the cerebrospinal fluid is a common practice in the medical field, and medical staff may obtain a rich diagnostic message by analyzing the process of the cerebrospinal fluid for identifying various diseases in the central nervous system.
The lumbar puncture, also called spinal puncture, is a medical procedure commonly used for collecting cerebrospinal fluid samples, and when the medical procedure is performed, firstly, a patient can lie on an examination bed back to the side of a medical staff, can sit straight on a seat, then the head is bent forwards, bends down and hugs the knees, and exposes lumbar gaps to the greatest extent, so that the success rate of collecting cerebrospinal fluid is improved.
After positioning the patient, the medical staff can disinfect and inject local anesthetic at the puncture position to relieve pain during the puncture, the puncture procedure is usually performed at the position between the third lumbar vertebra and the fourth lumbar vertebra, or at the position between the fourth lumbar vertebra and the fifth lumbar vertebra, when the lumbar puncture needle is inserted into the lumbar gap and enters the subarachnoid space, the needle core in the lumbar puncture needle is taken out, then cerebrospinal fluid is drained into three or four sterile test tubes, the collected cerebrospinal fluid volume is one to ten milliliters, after the puncture, the medical staff can pull out the lumbar puncture needle, cover the puncture part by gauze, and send the collected cerebrospinal fluid to a laboratory for testing.
However, conventional methods of collecting cerebrospinal fluid samples have a number of disadvantages, each of which is now described below.
Firstly, in the conventional collection method, a plurality of test tubes are required to collect cerebrospinal fluid samples, and in the process of transferring cerebrospinal fluid to the plurality of test tubes, the cerebrospinal fluid samples are exposed to the external environment, and risk of polluting the samples exists, which affects the accuracy of analyzing the cerebrospinal fluid.
Second, the use of several tubes to collect a cerebrospinal fluid sample requires multiple transfers of the tube, increasing the operational complexity of the collection process and the likelihood of errors, resulting in a process that requires a medical professional with a high skill level to perform smoothly.
In addition, the conventional method for collecting the cerebrospinal fluid sample also has the problem that human tissues remain on the needle, wherein the human tissues can be skin tissues, muscle tissues, arachnoid tissues and the like, and the residual human tissues can block the needle, so that the cerebrospinal fluid flow is blocked, and the process of collecting the cerebrospinal fluid sample cannot be smoothly performed.
Again, the body tissue remaining on the needle may cause greater resistance to penetration and increase pain and discomfort to the patient.
Again, human tissue remaining on the needle may be mixed into the collected cerebrospinal fluid sample, affecting the purity of the cerebrospinal fluid sample, resulting in inaccurate laboratory analysis results.
Finally, in the traditional puncturing process, the flow rate of cerebrospinal fluid is not easy to control, the situation that the enough cerebrospinal fluid sample volume cannot be collected is caused by too low flow rate, and too high flow rate can collect too much cerebrospinal fluid sample volume and cause the situation that the patient has headache or low craniocerebral pressure symptoms. As described above, this is a major disadvantage of conventional methods of collecting cerebrospinal fluid samples.
Disclosure of Invention
The technical scheme adopted by the invention is as follows: the medical clinical cerebrospinal fluid information acquisition method comprises the following steps:
The first step, the liquid taking pipe is inserted into human body by puncture, the front end of the liquid taking pipe is immersed into cerebrospinal fluid in subarachnoid space of human body, the liquid taking pipe comprises a pipe body, a puncture part and a lateral liquid taking port,
A second step of extracting cerebrospinal fluid by using the liquid-extracting tube, obtaining quantitative cerebrospinal fluid in the liquid-extracting tube, the liquid-extracting tube further comprising a quantitative extractor comprising a piston body,
Third, the whole liquid taking tube is removed from the human body, the quantitative cerebrospinal fluid is sealed in the liquid taking tube, the liquid taking tube is transferred to an information collecting laboratory,
A fourth step of converting the liquid taking tube into a cerebrospinal fluid releasing state, wherein the liquid taking tube further comprises a damage releasing structure, an external force is applied to the damage releasing structure, the external force can enable the damage releasing structure to fall off from the liquid taking tube, a releasing opening is formed on the liquid taking tube, the liquid taking tube is in the cerebrospinal fluid releasing state, the quantitative cerebrospinal fluid in the liquid taking tube can overflow to the outside of the liquid taking tube through the releasing opening,
Fifthly, quantitatively releasing the quantitative cerebrospinal fluid in the fluid taking tube for collecting cerebrospinal fluid information, moving the whole piston body in the second step downwards along the tube body, and quantitatively releasing the quantitative cerebrospinal fluid in the fluid taking tube by means of the thrust of the piston body to obtain released cerebrospinal fluid.
The beneficial effects of the invention are as follows:
The invention provides a medical clinical cerebrospinal fluid information acquisition method, which can independently hold a cerebrospinal fluid sample, prevent the cerebrospinal fluid sample from being exposed to the external environment and improve the accuracy of analyzing the cerebrospinal fluid sample.
The invention provides a medical clinical cerebrospinal fluid information acquisition method, which can independently move the acquisition device, can solve the problem that a test tube needs to be transferred for multiple times, and can smoothly carry out the process of collecting a cerebrospinal fluid sample.
The invention provides a medical clinical cerebrospinal fluid information acquisition method, which can solve the problem of the blockage of the flow of a cerebrospinal fluid sample caused by human tissues and can reduce the situation of wasting the cerebrospinal fluid.
The invention provides a medical clinical cerebrospinal fluid information acquisition method, which can solve the problem that human tissues are mixed into a collected cerebrospinal fluid sample and improve the purity of the cerebrospinal fluid sample.
Drawings
FIG. 1 is a schematic representation of the use of the present invention.
FIG. 2 is a schematic view of a piercing portion of the present invention.
FIG. 3 is a schematic view of a lateral liquid-taking port according to the present invention.
FIG. 4 is a schematic view of the location of a puncture point according to the present invention.
FIG. 5 is a schematic diagram of the operation of the present invention.
Fig. 6 is a schematic view of the action of the piston body of the present invention.
FIG. 7 is a schematic view of a liquid access closure and an external protrusion according to the present invention.
FIG. 8 is a schematic view of the present invention with a measured amount of cerebrospinal fluid stored in a tube.
Fig. 9 is a schematic view of the breakage relief structure of the present invention.
Fig. 10 is a schematic view showing the detachment of the breakage releasing structure of the present invention.
FIG. 11 is a schematic view of the force application tool of the present invention.
FIG. 12 is a schematic diagram of the operation of the force application tool of the present invention.
Fig. 13 is a schematic view of a breakage relief structure according to a second embodiment of the present invention.
Fig. 14 is a schematic view of a third embodiment of the breakage relief structure of the present invention.
Fig. 15 is an exploded view of a third embodiment of the breakage relief structure of the present invention.
Fig. 16 is a schematic structural view of a third embodiment of the breakage relief structure of the present invention.
FIG. 17 is a schematic diagram of the quantitative release of quantitative cerebrospinal fluid according to the invention.
Detailed Description
As shown in fig. 1 to 17, a medical clinical cerebrospinal fluid information collection method, comprising the steps of:
as shown in fig. 1 to 5, in a first step, the liquid taking tube 100 is inserted into a human body by piercing, so that the front end of the liquid taking tube 100 is immersed in cerebrospinal fluid a in the subarachnoid space of the human body.
In practice, the liquid taking tube 100 can perform a puncturing motion between the third lumbar vertebra and the fourth lumbar vertebra or between the fourth lumbar vertebra and the fifth lumbar vertebra of the human body.
The liquid taking tube 100 comprises a tube body 210, a puncturing part 220 and a lateral liquid taking opening 230, wherein the puncturing part 220 is arranged at the front end of the tube body 210, the lateral liquid taking opening 230 is arranged at the lateral position of the puncturing part 220,
The piercing section 220 has a piercing head 240 and a lateral cavity 250, wherein the lateral cavity 250 is located between the piercing head 240 and the wall 211 of the tube 210, the lateral access port 230 is disposed on a bottom 251 of the lateral cavity 250, and the lateral access port 230 is in communication with the lumen 213 of the tube 210.
The puncture head 240 has a puncture point 241, the puncture point 241 is located at the foremost position of the puncture head 240, in practice, the puncture point 241 first contacts the human body when performing the puncture operation, and breaks the human tissue and performs the puncture operation mainly by means of the puncture point 241, the puncture point 241 is biased to one side of the central axis 212 of the tube 210, and a vertical bias distance D1 is provided between the puncture point 241 and the central axis 212.
The puncturing point 241 is convexly arranged below the lateral liquid taking port 230, a protruding height D2 is arranged between the puncturing point 241 and the pipe wall 211 above the lateral liquid taking port 230, the puncturing head 240 covers the lateral liquid taking port 230 between the puncturing head 240 and the pipe body 210, when in puncturing operation, the puncturing head 240 breaks open human tissues and performs puncturing operation, the human tissues cannot directly contact the lateral liquid taking port 230, and further, the situation that the human tissues block the lateral liquid taking port 230 is avoided when in puncturing operation.
As shown in FIGS. 6 to 7, in the second step, cerebrospinal fluid is withdrawn by the liquid-withdrawing tube 100, and a quantitative amount of cerebrospinal fluid A1 is obtained in the liquid-withdrawing tube 100.
The liquid taking tube 100 further comprises a quantitative extractor 310, wherein the quantitative extractor 310 comprises a piston body 320, the piston body 320 is made of elastic materials, such as silica gel, rubber, etc., the piston body 320 is provided with a body 321, a liquid taking opening closing body 322 and an outer convex body 323, the liquid taking opening closing body 322 is arranged on one side of the body 321, and the outer convex body 323 is connected to the liquid taking opening closing body 322.
The liquid taking port closing body 322 corresponds to the lateral liquid taking port 230, when the liquid taking tube 100 is inserted into a human body in the first step, the body 321 is inserted into the bottom of the lumen 213 of the tube body 210, the liquid taking port closing body 322 is plugged inside the lateral liquid taking port 230, and the outer convex body 323 is convexly arranged in the lateral liquid taking port 230.
In the second step, when the liquid taking tube 100 is used to draw cerebrospinal fluid, the piston body 320 moves up along the lumen 213 of the tube body 210, and at this moment, the liquid taking port closing body 322 drives the outer convex body 323 to move up, so that the outer convex body 323 generates physical deformation, the outer convex body 323 is retracted into the lumen 213 and moves up synchronously with the liquid taking port closing body 322, and the piston body 320 and the lumen 213 can move in a tight fit manner by means of retracting and moving up the outer convex body 323, so that the suction force of the liquid taking tube 100 for drawing cerebrospinal fluid is larger, thereby improving the suction efficiency.
In particular embodiments, the quantitative extractor 310 further includes an extractor 330, and the extractor 330 may be operated manually or automatically, and the techniques of the extractor 330 are well known in the art and will now be briefly described below. When the extractor 330 adopts a manual mode, the extractor 330 is a manual piston push rod, the manual piston push rod is connected to the piston body 320, a dosage mark can be set on the tube body 210 to realize quantitative extraction, when the extractor 330 adopts an automatic mode, the extractor 330 is a piston push rod, one end of the piston push rod is connected to the piston body 320, the other end of the piston push rod is connected with a motor or an air pressure or hydraulic action unit, and the action unit defines the rated moving distance of the piston push rod to realize quantitative extraction.
As shown in fig. 8, in a third step, the whole of the liquid taking tube 100 is removed from the human body, the quantitative cerebrospinal fluid A1 is sealed in the liquid taking tube 100, and the liquid taking tube 100 is transferred to an information collecting laboratory.
The quantitative cerebrospinal fluid A1 is collected and transferred in a third step, so that efficient collection and transfer can be realized, and the pollution-free sealing and storing efficiency can be improved.
In practice, since the dosage of cerebrospinal fluid required for performing the information collection assay on the cerebrospinal fluid is small, the dosage is sufficient to use in a manner of directly collecting and sealing the quantitative cerebrospinal fluid A1 in the liquid-collecting tube 100, and the prior art has a problem that the dosage is unnecessarily wasted through a large number of catheters and a container.
As shown in fig. 9 to 16, in a fourth step, the liquid taking tube 100 is converted into a cerebrospinal fluid releasing state.
The liquid taking tube 100 further comprises a breakage releasing structure 410, an external force F is applied to the breakage releasing structure 410, the external force F can enable the breakage releasing structure 410 to fall off from the liquid taking tube 100, a releasing opening 420 is formed on the liquid taking tube 100, the liquid taking tube 100 is in the cerebrospinal fluid releasing state, the quantitative cerebrospinal fluid A1 in the liquid taking tube 100 can overflow to the outside of the liquid taking tube 100 through the releasing opening 420 to perform an information collecting action of cerebrospinal fluid, and the breakage releasing structure 410 is arranged on the tube body 210 of the liquid taking tube 100.
In particular embodiments, there are various embodiments that can implement the functionality of the rupture release structure 410, each of which is now described below.
As shown in fig. 9 to 10, in the first embodiment, the breakage releasing structure 410 includes a frangible groove 510, the frangible groove 510 is disposed on the tube body 210 of the liquid taking tube 100, the frangible groove 510 communicates with the lateral liquid taking port 230 to form the breakage releasing structure 410, and the releasing port 420 formed when the breakage releasing structure 410 is detached from the liquid taking tube 100 is inclined and opened.
In practice, the lateral cavity 250 has a force applying surface 511, the puncture point 241 is located at the lower end of the force applying surface 511, and the force applying surface 511 is located at the lower end of the lateral liquid outlet 230.
As shown in fig. 11 to 12, in the embodiment, the breakage releasing structure 410 can be folded down from the liquid taking tube 100 by a force applying tool 520, and the force applying tool 520 includes a force applying plate 521, a connecting ring plate 522 and a holding plate 523, wherein the connecting ring plate 522 is connected between the force applying plate 521 and the holding plate 523.
When the breakage releasing structure 410 is detached, the force applying plate 521 is pressed against the force applying surface 511, the holding plate 523 is pressed against the liquid taking tube 100, the external force F acts on the force applying plate 521 to achieve the purpose of breaking the breakage releasing structure 410 from the liquid taking tube 100 along the position of the frangible groove 510, and in practice, the force applying tool 520 further includes a force applying protrusion 524, the force applying protrusion 524 is disposed at an end of the force applying plate 521, so that a user can apply the external force F on the force applying plate 521 conveniently.
As shown in fig. 13, in the second embodiment, the breakage releasing structure 410 includes a frangible groove 510, the frangible groove 510 is disposed around the tube body 210 of the liquid taking tube 100, the piercing portion 220 and the lateral liquid taking port 230 are both located below the frangible groove 510, and the releasing port 420 is formed at the position of the frangible groove 510 when the breakage releasing structure 410 is detached from the liquid taking tube 100.
As shown in fig. 14 to 16, the third embodiment of the liquid taking tube 100' includes a tube body 210', a puncturing portion 220', and a lateral liquid taking port 230', wherein the puncturing portion 220' is movably sleeved on the tube body 210', the lateral liquid taking port 230' is disposed at a lateral position of the tube body 210', and the lateral liquid taking port 230' is in communication with the lumen 213' of the tube body 210 '.
The piercing portion 220' has a piercing head 240' and a plurality of collars 260', the plurality of collars 260' are fixedly coupled to the piercing head 240', the piercing head 240' has a piercing point 241', and the piercing point 241' is located at the foremost position of the piercing head 240 '.
In practice, when performing the puncturing operation, the puncturing point 241 'first contacts the human body, and the puncturing point 241' is mainly used for puncturing human tissue and performing the puncturing operation, the puncturing point 241 'is offset at one side of the central axis 212' of the tube body 210', and a vertical offset distance D1' is provided between the puncturing point 241 'and the central axis 212'.
The puncturing point 241' is convexly arranged below the lateral liquid taking port 230', a protruding height D2' is arranged between the puncturing point 241' and the pipe wall 211' above the lateral liquid taking port 230', the puncturing head 240' covers the lateral liquid taking port 230' between the puncturing head 240' and the pipe body 210', when in puncturing, the puncturing head 240' breaks human tissues and performs puncturing, the human tissues cannot directly contact the lateral liquid taking port 230', and further, the situation that the human tissues block the lateral liquid taking port 230' is avoided when in puncturing.
The puncture part 220' forms the breakage releasing structure 410, the puncture part 220' is removed from the tube body 210', the lateral liquid taking opening 230' forms the releasing opening 420, and the quantitative cerebrospinal fluid A1 in the liquid taking tube 100' can overflow to the outside of the liquid taking tube 100' through the lateral liquid taking opening 230', so as to perform the information collecting action of cerebrospinal fluid.
As shown in fig. 17, in the fifth step, the quantitative cerebrospinal fluid A1 in the liquid-collecting tube 100 is quantitatively released for collecting information of the cerebrospinal fluid.
The piston body 320 in the second step is moved down along the lumen 213 of the tube body 210, and the quantitative cerebrospinal fluid A1 in the liquid-taking tube 100 is quantitatively released by the pushing force of the piston body 320, so as to obtain the released cerebrospinal fluid A2.
In practice, the released cerebrospinal fluid A2 may be placed in a vessel for testing, information collection, or other medical information collection activities.
Claims (10)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411055682.6A CN118948341B (en) | 2024-08-02 | 2024-08-02 | Liquid pipe is got to clinical cerebrospinal fluid of medical treatment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411055682.6A CN118948341B (en) | 2024-08-02 | 2024-08-02 | Liquid pipe is got to clinical cerebrospinal fluid of medical treatment |
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| CN118948341A true CN118948341A (en) | 2024-11-15 |
| CN118948341B CN118948341B (en) | 2025-12-09 |
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| GB1450853A (en) * | 1974-01-09 | 1976-09-29 | Jamshidi K | Muscle biopsy needle |
| US20080228104A1 (en) * | 2004-03-11 | 2008-09-18 | Uber Arthur E | Energy Assisted Medical Devices, Systems and Methods |
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|---|---|
| CN118948341B (en) | 2025-12-09 |
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