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CN118924381B - A multi-stage thrombus removal device - Google Patents

A multi-stage thrombus removal device Download PDF

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Publication number
CN118924381B
CN118924381B CN202411429551.XA CN202411429551A CN118924381B CN 118924381 B CN118924381 B CN 118924381B CN 202411429551 A CN202411429551 A CN 202411429551A CN 118924381 B CN118924381 B CN 118924381B
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China
Prior art keywords
spiral
balloon
inner tube
tube
balloon body
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Active
Application number
CN202411429551.XA
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Chinese (zh)
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CN118924381A (en
Inventor
李虎
梁坤
韩梁
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Shanghai Hope Medical Devices Co ltd
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Shanghai Hope Medical Devices Co ltd
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Priority to CN202411429551.XA priority Critical patent/CN118924381B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/00867Material properties shape memory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/00902Material properties transparent or translucent
    • A61B2017/00915Material properties transparent or translucent for radioactive radiation
    • A61B2017/0092Material properties transparent or translucent for radioactive radiation for X-rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

一种多级血栓清除装置,包括:螺旋球囊,螺旋球囊包括囊体和塑形管,囊体远端的螺旋直径大于近端,整体呈锥形,囊体在伸直状态下为直筒状;塑形管包括内管、弹簧圈和显影环;塑形管位于囊体内的部分为锥形螺旋结构;内管为镍钛合金管,远端连接有TIP头;弹簧圈缠绕在内管上,弹簧圈的远端与内管的远端固定连接;显影环设置在塑形管位于囊体段的两端;输送导管包括牵引腔和充盈腔,塑形管位于牵引腔的部分为平直状;操作手柄包括握柄、旋钮、充盈座和导丝座;旋钮内又包括滑块和螺旋滑槽,螺旋滑槽位于旋钮上,旋转旋钮时,通过螺旋滑槽带动滑块做前后运动,内管连接在滑块上并延伸出操作手柄,延伸出的部分与导丝座连接。

A multi-stage thrombus removal device comprises: a spiral balloon, the spiral balloon comprises a balloon body and a shaping tube, the spiral diameter of the distal end of the balloon body is larger than that of the proximal end, and the balloon body is tapered as a whole, and the balloon body is a straight cylinder in the straightened state; the shaping tube comprises an inner tube, a spring coil and a developing ring; the part of the shaping tube located in the balloon body is a tapered spiral structure; the inner tube is a nickel-titanium alloy tube, and a TIP head is connected to the distal end; the spring coil is wound on the inner tube, and the distal end of the spring coil is fixedly connected to the distal end of the inner tube; the developing ring is arranged at both ends of the shaping tube located in the balloon body section; the delivery catheter comprises a traction cavity and a filling cavity, and the part of the shaping tube located in the traction cavity is straight; the operating handle comprises a grip, a knob, a filling seat and a guide wire seat; the knob comprises a slider and a spiral groove, the spiral groove is located on the knob, and when the knob is rotated, the slider is driven to move forward and backward through the spiral groove, the inner tube is connected to the slider and extends the operating handle, and the extended part is connected to the guide wire seat.

Description

Multistage thrombus clearing device
Technical Field
The invention relates to the field of medical instruments, in particular to a multistage thrombus removing device.
Background
Thrombus is easily caused when blood flow of human body is slow, blood vessel wall is damaged, blood is in a hypercoagulable state, and the like. In vascular surgery emergency treatment, a larger part of patients are emergently treated by sudden venous thrombosis or arterial embolism, if the patients are not treated timely, once the embolism time is too long, limb ischemia amputation and even thrombus shedding exist to cause pulmonary embolism risk, and once the pulmonary embolism risk occurs, the pulmonary embolism risk is greatly threatened to property and life safety of people. Current conventional methods for treating acute ischemic stroke include two broad categories, interventional thrombolysis and mechanical thrombolysis.
The interventional thrombolysis is that a catheter injects a thrombolytic machine into the vicinity of a lesion in a blood vessel where the lesion is located, and a very high thrombolytic agent concentration is formed at the local moment of the lesion, thereby accelerating the thrombolysis speed and further increasing the chance of vascular recanalization. For large and long-length thrombi, very large doses of thrombolytic drug are required to dissolve such large clots, but this is likely to cause complications, is at high risk, and often does not achieve the desired effect. Mechanical embolus removal includes thrombectomy, laser thrombolysis, capture embolus removal and capture mesh embolus removal. Thrombectomy is thorough in thrombus removal, but the damage to the vessel wall is excessive, and various complications are easily caused. The laser thrombus breaking operation has high difficulty, the laser energy is low and ineffective, the blood vessel is damaged when the energy is too high, and various complications are also easy to cause. The capture type thrombus taking operation is simple, the damage to the blood vessel wall is small, but the blood clot can not be covered frequently. The operation of capturing net and taking the thrombus is simple, but the capturing net cannot be used in intracranial blood vessels due to the large volume.
The existing Fogarty thrombus taking balloon catheter is a balloon catheter with a closed front end, the balloon is made of latex materials, and two ends of the balloon can be developed. After the balloon enters the target blood vessel, the balloon is filled, the thrombus in the occluded blood vessel is crushed, and the thrombus can be dragged out of the body along with the balloon. However, the diameter of the blood vessel is changed, when the thrombus is taken from the proximal end to the distal end, the diameter of the blood vessel is changed from large to small, the diameter of the balloon is fixed, when the balloon is pulled to take the thrombus, the damage to the blood vessel at the distal end is large, and when the thrombus is taken from the distal end to the proximal end, the thrombus can be taken at the extreme end uncleanly. And the Fogarty thrombus taking balloon catheter is a single balloon, and only single thrombus taking is carried out when thrombus taking, sometimes the thrombus taking balloon catheter cannot be completely taken, and multiple thrombus taking is possibly required, so that the vascular injury is large.
When a closed long-length thrombus is formed in a blood vessel, the guide wire cannot pass through, and the balloon catheter cannot be conveyed to the distal end of the thrombus through the guide wire. When the vascular stenosis caused by thrombus is severe, the balloon catheter cannot be effectively delivered through the sheath when the sheath cannot pass through.
Therefore, the thrombus taking balloon catheter which can adapt to the change of the diameter of a blood vessel, can achieve the effect of multiple cleaning by single thrombus taking and can pass through a narrow blood vessel channel is required by the current clinic.
Disclosure of Invention
The invention aims to overcome the defects and provide a multi-stage thrombus removal device.
The technical scheme adopted by the invention is as follows:
a multi-stage thrombi removal device, comprising:
The spiral balloon comprises a balloon body and a shaping tube, wherein the spiral diameter of the far end of the balloon body is larger than that of the near end, the balloon body is in a straight cylinder shape in a straightening state, and the spiral diameter is 1-5 times of the diameter of the balloon body in the straight cylinder state; the shaping tube comprises an inner tube, a spring ring and a developing ring; the device comprises a bag body, a control handle, a spring ring, a developing ring, a conveying guide pipe, a control handle, a slider and a spiral chute, wherein the portion of the plastic pipe in the bag body is of a conical spiral structure, the plastic pipe in the bag body is located in the center of the bag body, the taper of the plastic pipe is the same as that of the bag body, the inner pipe is a nickel-titanium alloy pipe, the distal end of the spring ring is connected with a TIP head, the spring ring is wound on the inner pipe, the distal end of the spring ring is fixedly connected with the distal end of the inner pipe, the developing ring is arranged on the two ends of the plastic pipe located at the bag body section, the conveying guide pipe comprises a traction cavity and a filling cavity, the traction cavity is used for passing through the plastic pipe, the portion of the plastic pipe located in the traction cavity is in a straight shape, the control handle comprises a grab handle, a knob, a filling seat and a guide wire seat, the slider and the spiral chute are located in the knob, the knob is located on the knob, when the knob is rotated, the slider is driven to move forwards and backwards through the spiral chute, the inner pipe is connected to the slider, the inner pipe and extends out of the control handle, and the guide wire is in a straight state when the inner pipe is connected with the guide wire, and the spring layer tends to be pulled tightly in parallel to each other.
Preferably, the capsule is a compliant or semi-compliant material.
Preferably, the TIP head is tapered for guiding the spiral balloon.
Preferably, a guide wire hole is arranged on the TIP head.
Preferably, the distal end of the spring coil and the distal end of the inner tube are connected together by welding.
Drawings
FIG. 1 is a multi-stage thrombi removal device, the present invention;
FIG. 2 is a side view of a spiral balloon;
FIG. 3 is a schematic view of a plastic tube 1;
FIG. 4 is a schematic view of a plastic tube 2;
FIG. 5 is a schematic view of a spring coil;
FIG. 6 illustrates a thrombus removal procedure using the present invention;
fig. 7 shows another embodiment of a spiral balloon.
Detailed Description
Embodiments of the present invention are described in further detail below with reference to the accompanying drawings and examples. The following examples are illustrative of the invention but are not intended to limit the scope of the invention.
A multi-stage thrombi removal device, comprising:
A spiral balloon 100, wherein the spiral balloon 100 has a conical spiral structure. The spiral balloon 100 includes an outer balloon 120, an inner shaping tube 130, and a TIP head 110 at the head end. Balloon 120 has a tapered spiral configuration with a gradually decreasing spiral diameter from distal to proximal, and an overall tapered shape with a tapered tip connected to delivery catheter 200. The balloon 120 is in a straight cylinder shape when being straightened, the diameters of the whole straight cylinders are the same, the spiral diameter of the balloon 120 is 1-5 times of the diameter of the straight cylinder in the straightened state, and the balloon 120 is a compliant and semi-compliant balloon and has a certain deformation quantity.
The plastic tube 130 comprises an inner tube 133, a spring ring 134 and developing rings 131 and 132, wherein the part of the plastic tube 130 positioned in the balloon body 120 is of a spiral structure and is in a conical shape as a whole, the plastic tube 130 of the part is positioned in the center of the balloon body 120, namely, the spiral diameter, the interval of each layer of spiral and the taper of the spiral are the same, the inner tube 133 is a nickel-titanium alloy tube, the distal end of the inner tube 133 is connected with a TIPS head, and the lumen of the inner tube 133 is mainly used for passing through a guide wire, so that after the guide wire is in place, the spiral balloon can be conveyed in place along the guide wire. The spring ring is wound on the inner tube, the distal end of the spring ring is fixedly connected with the distal end of the inner tube, and the rest parts can slide mutually. The developing rings are arranged at two ends of the plastic tube, which are positioned at the capsule body section, and are used for developing and positioning. When the plastic tube is in a spiral state, a certain gap exists between each layer of the spring ring, and a certain angle exists between each layer of the spring ring, as shown in fig. 4, when the inner tube is pulled, the spring rings are tightened and are in a parallel state, the gap also disappears, at the moment, the plastic tube is in a flat state when seen from the whole, and when the inner tube is loosened, the plastic tube is in a spiral state again.
An inner hole is arranged in the TIP head and is the same as the plastic tube, so that the guide wire can be conveniently inserted. When the thrombus is conveyed, the vascular stenosis is serious due to the thrombus, and when the mode of conveying the spiral balloon to the distal end of the thrombus through the sheath tube is inappropriate, the whole spiral balloon is changed from a spiral shape to a straight shape by stretching the inner tube 133 so as to facilitate conveying through the thrombus stenosis.
The conical spiral saccule can reduce the damage to the blood vessel, and can increase the number of times of thrombus taking, so that the thrombus taking is cleaner without damaging the blood vessel. When the thrombus is removed, the spiral saccule is often placed at a position close to the heart, when the thrombus is removed, the spiral saccule moves from the position close to the heart to the distal end, at the moment, the diameter of a blood vessel is from large to small, when the spiral saccule is pulled backwards, a part of thrombus is removed from the spiral saccule section with smaller spiral diameter, at the moment, the thrombus with larger diameter is still in the middle of the spiral saccule section, the remaining thrombus on the blood vessel wall is further removed through the spiral saccule section with larger diameter, at the moment, if the thrombus is still remained on the blood vessel wall, the spiral saccule section with larger diameter is used for removing the remaining thrombus, so that the thrombus is taken out in a segmented mode, the problem of unclean thrombus removal once is avoided, meanwhile, the cross section of the spiral saccule in a straightened state is far smaller than the diameter of the blood vessel, the damage to the blood vessel wall is not caused by the overlarge diameter of the spiral saccule, because when the inner cavity of the blood vessel is smaller, the stress of the spiral saccule is enlarged, at the moment, the spiral saccule is stretched towards the axial direction, so that the cross section diameter of the whole spiral saccule is reduced, and the damage to the blood vessel wall is avoided.
When the device is manufactured, the spring ring 134 is tightly wound on the outer surface of the inner tube 133, then the required spiral structure is formed by molding through a die, then the distal spring ring 134 and the inner tube 133 are fixed together by welding, the proximal end of the spring ring 134 and the inner tube 133 are free to move, but the spring ring 134 needs to be fixed at the distal end of the conveying catheter 2 so as to play a role in fixation.
The conveying catheter 200 is of a double-cavity structure, the conveying catheter 200 is divided into a traction cavity and a filling cavity, the traction cavity is mainly used for enabling the conveying catheter to smoothly slide in the cavity through a plastic pipe 130, the part of the plastic pipe, which is located in the traction cavity, is in a straight shape, and the filling cavity is mainly used for injecting water into the spiral balloon, so that the spiral balloon is expanded and expanded.
The device comprises an operating handle 300, wherein the operating handle is provided with a handle grip 310, a knob 320, a filling seat 330 and a guide wire seat 340, the handle grip 310 is mainly used for holding, the knob 320 is internally provided with a sliding block 321 and a spiral chute 322 on the knob, the sliding block 321 is fixedly connected with an inner tube 133, the sliding block 321 and the gear 322 are driven to move relatively by rotating the knob 320, the inner tube 133 is driven to move forwards or backwards, the inner tube 133 and the sliding block 321 are fixed and extend out of the operating handle, the guide wire seat 340 is connected with the inner tube 133 and is used for inserting a guide wire and guiding the balloon to be conveyed, and the filling seat 330 is mainly used for injecting liquid to fill the balloon or extracting liquid and releasing the action of the balloon.
In use, the knob 320 is rotated to stretch the molding tube 133 backward, thereby tightening and straightening the spring ring 134 to make the whole capsule 120 become a straight state, and at this time, the transportation is facilitated. When the distal end of the thrombus is reached through the thrombus segment, the knob 320 is rotated again to restore the coil 134 to its original shape, i.e., the spiral shape, at which time the shaping tube 130 also becomes spiral and the spiral balloon is inflated through the inflation seat 330.
In another embodiment, when the guide wire cannot pass through a blood vessel blocked by thrombus, the inner tube 133 can be designed into a solid structure, the guide wire is not needed for guiding when in use, and after the inner tube 133 is pulled and stretched, the balloon is in a straightened state, and thrombus is directly punctured forwards to replace the guide wire.
In another embodiment, when the vessel diameter does not vary much, the entire spiral balloon is of an equal diameter spiral shape, facilitating cleaner removal of the thrombus, as shown in FIG. 7.
In another embodiment, delivery catheter 200 is a single lumen structure, where inner tube 133 passes through the lumen of delivery catheter 200, where inner tube 33 shares the body with the filling lumen, and where fluid enters the balloon from the gap between inner tube 133 and the filling lumen.
The described embodiments are to be considered in all respects only as illustrative and not restrictive. The scope of the disclosure is, therefore, indicated by the appended claims rather than by the foregoing description. All changes which come within the meaning and range of equivalency of the claims are to be embraced within their scope. The invention is not limited to the embodiments described above, i.e. it is not meant that the invention has to be carried out in dependence on the embodiments described above. It should be apparent to those skilled in the art that any modification of the present invention, equivalent substitution of selected raw materials, addition of auxiliary components, selection of specific modes, etc. fall within the scope of the present invention and the scope of disclosure.

Claims (5)

1. A multi-stage thrombi removal device, comprising:
The spiral balloon comprises a balloon body and a plastic tube, wherein the spiral diameter of the far end of the balloon body is larger than that of the near end, the balloon body is in a straight cylinder shape in an extending state and is 1-5 times of the diameter of the balloon body in the straight cylinder shape, the plastic tube comprises an inner tube, a spring ring and a developing ring, the part of the plastic tube in the balloon body is in a conical spiral structure, the plastic tube in the balloon body is positioned at the center of the balloon body, the taper of the plastic tube is the same as that of the balloon body, the inner tube is a nickel-titanium alloy tube, the far end of the plastic tube is connected with a TIP head, the spring ring is wound on the inner tube, the far end of the spring ring is fixedly connected with the far end of the inner tube, and the developing ring is arranged at two ends of the plastic tube in the balloon body section;
The conveying catheter comprises a traction cavity and a filling cavity, the traction cavity is used for passing through the plastic pipe, and the part of the plastic pipe, which is positioned in the traction cavity, is straight;
The rotary knob comprises a handle, a knob, a filling seat and a wire guide seat, wherein the knob comprises a sliding block and a spiral chute, the spiral chute is positioned on the knob, when the knob is rotated, the sliding block is driven to move forwards and backwards through the spiral chute, the inner tube is connected to the sliding block and extends out of the handle, the extending part of the inner tube is connected with the wire guide seat, when the knob is rotated, the inner tube pulls the spring ring, at the moment, each layer of the spring ring is tightly attached and tends to be parallel to each other, and the spring ring tends to be in a straight state when seen from the whole.
2. The multiple level thrombectomy device of claim 1, wherein the balloon is of a compliant or semi-compliant material.
3. The multiple stage thrombi elimination device of claim 1, wherein said TIP head is tapered for guiding said spiral balloon.
4. The multiple level thrombi elimination device of claim 1, wherein said TIP head is provided with a guidewire port.
5. The multiple level thrombi elimination device of claim 1, wherein said distal end of said spring coil and said distal end of said inner tube are joined together by welding.
CN202411429551.XA 2024-10-14 2024-10-14 A multi-stage thrombus removal device Active CN118924381B (en)

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CN118924381B true CN118924381B (en) 2025-03-21

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Citations (1)

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Publication number Priority date Publication date Assignee Title
US4762130A (en) * 1987-01-15 1988-08-09 Thomas J. Fogarty Catheter with corkscrew-like balloon

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WO2008117256A2 (en) * 2007-03-27 2008-10-02 Intratech Medical Ltd. Spiral balloon catheter
CN205126342U (en) * 2015-11-06 2016-04-06 深圳迈德科技有限公司 Thrombus suction device
US20210085931A1 (en) * 2019-09-25 2021-03-25 Thrombolex, Inc. Balloon basket catheter device
CN115177321B (en) * 2022-06-14 2023-06-20 上海腾复医疗科技有限公司 Multifunctional thrombus removing device
CN115227337B (en) * 2022-08-01 2024-01-12 上海腾复医疗科技有限公司 Vascular opening device
CN220530056U (en) * 2023-06-26 2024-02-27 上海宏普医疗器械有限公司 Cell collection device
CN117137575B (en) * 2023-09-06 2024-06-25 上海心玮医疗科技股份有限公司 Flaring suction catheter with bolt cutting function
CN117959050A (en) * 2024-04-01 2024-05-03 上海宏普医疗器械有限公司 Recoverable spiral sacculus support

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762130A (en) * 1987-01-15 1988-08-09 Thomas J. Fogarty Catheter with corkscrew-like balloon

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