CN118781215B - A medical image acquisition and analysis method for endocrine patients - Google Patents
A medical image acquisition and analysis method for endocrine patients Download PDFInfo
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Abstract
The invention relates to the technical field of image processing, in particular to a medical image acquisition and analysis method for endocrine patients, which comprises the steps of acquiring an MRI endocrine patient detection gray level image, analyzing distribution conditions of annular closed edge textures in an endocrine region to obtain titanium alloy texture degrees, obtaining an initial titanium alloy endocrine region and a normal endocrine region according to the titanium alloy texture degrees, obtaining titanium alloy tissue degrees according to the initial titanium alloy endocrine region and the normal endocrine region, analyzing blurring conditions of inner edge texture information of the initial titanium alloy endocrine region according to the titanium alloy tissue degrees to obtain inner edge blurring degrees, dividing a titanium alloy artifact region from the initial titanium alloy endocrine region according to the inner edge blurring degrees, and acquiring and analyzing the MRI endocrine patient detection gray level image. The invention improves the acquisition precision of the medical image acquired by the endocrine patient.
Description
Technical Field
The invention relates to the technical field of image processing, in particular to a medical image acquisition and analysis method for endocrine patients.
Background
The nuclear Magnetic Resonance (MRI) technology is one of the main technical means of the existing medical image acquisition because of the advantages of no need of using contrast agent, no radiation injury, multi-azimuth imaging and the like. In order to facilitate nuclear Magnetic Resonance (MRI) examination of endocrine patients, for endocrine patients who need to be assisted in their lives by installing medical implants, existing medical techniques may select medical implants made of titanium alloy to reduce the safety risk of nuclear Magnetic Resonance (MRI) of endocrine patients.
For endocrine patients with titanium alloy implants, due to individual differences in the endocrine patients, various degrees of inflamed areas are generated between the corresponding titanium alloy implants and body tissues, and the inflamed areas form a certain degree of artifacts during the process of acquiring images by a Magnetic Resonance (MRI) technology, thereby interfering with the accuracy of acquiring medical images for the endocrine patients.
Disclosure of Invention
The invention provides a medical image acquisition and analysis method for endocrine patients, which aims to solve the existing problems that due to the fact that individual conditions of the endocrine patients are different, different degrees of inflamed areas are generated between corresponding titanium alloy implants and body tissues, and certain degrees of artifacts are formed in the process of acquiring images through a Magnetic Resonance (MRI) technology, so that the accuracy of acquiring medical images for the endocrine patients is interfered.
The invention discloses a medical image acquisition and analysis method for endocrine patients, which adopts the following technical scheme:
the method comprises the following steps:
Acquiring an MRI endocrine patient detection gray scale image, wherein the MRI endocrine patient detection gray scale image comprises a plurality of endocrine areas;
Analyzing the distribution condition of the edge textures in each endocrine region in a ring-shaped closed state to obtain the titanium alloy texture degree of each endocrine region;
Comparing grain trend distribution differences between the initial titanium alloy endocrine region and other surrounding initial titanium alloy endocrine regions and normal endocrine regions to obtain titanium alloy tissue degree of each initial titanium alloy endocrine region;
analyzing the fuzzy condition of the internal edge texture information of the initial titanium alloy endocrine region according to the titanium alloy tissue degree to obtain the internal edge fuzzy degree of each initial titanium alloy endocrine region;
dividing a titanium alloy artifact region from the initial titanium alloy endocrine region according to the internal edge blurring degree, and collecting and analyzing the detection gray level map of the MRI endocrine patient according to the titanium alloy artifact region.
Preferably, the method for obtaining the texture degree of the titanium alloy comprises the following steps:
for any endocrine region, acquiring a plurality of initial titanium alloy edge textures in the endocrine region;
Analyzing the distribution condition of the distance between adjacent initial titanium alloy edge textures to obtain the texture closure degree of the endocrine region;
analyzing the direction extension change condition of the adjacent initial titanium alloy edge textures to obtain the texture circularity of the endocrine region;
And obtaining the titanium alloy texture degree of the endocrine region according to the texture closure degree and the texture circularity, wherein the titanium alloy texture degree is positively correlated with the texture closure degree and positively correlated with the texture circularity.
Preferably, the method for obtaining the texture closure degree comprises the following steps:
Analyzing the overall variation fluctuation condition of the port distance between the adjacent initial titanium alloy edge textures to obtain the texture closure degree of the endocrine region.
Preferably, the method for obtaining the texture circularity comprises the following steps:
Analyzing the offset smooth condition of the port degrees between the adjacent initial titanium alloy edge textures to obtain the texture circularity of the endocrine region.
Preferably, the method for obtaining the tissue degree of the titanium alloy comprises the following steps:
Taking any initial titanium alloy endocrine region as a target endocrine region, analyzing consistent distribution of texture trend between the target endocrine region and other surrounding normal endocrine regions, and obtaining normal neighborhood texture consistency of the target endocrine region;
Analyzing consistent distribution of texture trend between the target endocrine region and other surrounding initial titanium alloy endocrine regions to obtain titanium alloy neighborhood texture consistency of the target endocrine region;
And obtaining the titanium alloy tissue degree of the target endocrine region according to the difference between the normal neighborhood texture consistency and the titanium alloy neighborhood texture consistency.
Preferably, the method for obtaining the normal neighborhood texture consistency degree comprises the following steps:
Taking each normal endocrine region as a comparison normal endocrine region in a preset normal endocrine region range of the target endocrine region, acquiring a target texture fitting degree mean value of the target endocrine region, and acquiring a texture fitting degree mean value of each comparison normal endocrine region;
And comparing the difference of the texture fitting degree mean value of the target and the texture fitting degree mean value of all the comparison normal endocrine regions to obtain the normal neighborhood texture consistency of the target endocrine regions.
Preferably, the method for obtaining the texture consistency of the titanium alloy neighborhood comprises the following steps:
Obtaining annular extension direction degrees of the target endocrine region in a preset initial titanium alloy endocrine region range of the target endocrine region;
And analyzing the association condition of the annular extension direction degree and the reference circumferential extension direction degree to obtain the texture consistency of the alloy neighborhood of the target endocrine region.
Preferably, the method for acquiring the internal edge blurring degree comprises the following steps:
For any initial titanium alloy endocrine region, analyzing the distribution distances between different edge textures and the centers of the initial titanium alloy endocrine region to obtain the center surrounding concentration of the initial titanium alloy endocrine region;
And analyzing the dispersion distribution condition among different edge textures according to the central surrounding concentration degree to obtain the internal edge blurring degree of the initial titanium alloy endocrine region.
Preferably, the method for obtaining the center surrounding concentration degree comprises the following steps:
obtaining the center interval distance between each edge texture center and the center of the initial titanium alloy endocrine region in the initial titanium alloy endocrine region;
And obtaining the center surrounding concentration degree of the initial titanium alloy endocrine region according to the center interval distance and the number of the edge texture centers, wherein the center surrounding concentration degree is inversely related to the number of the edge texture centers.
Preferably, the method for acquiring the titanium alloy artifact region comprises the following steps:
For any initial titanium alloy endocrine region, screening a plurality of titanium alloy endocrine regions from all initial titanium alloy endocrine regions according to the internal edge blurring degree;
for any one titanium alloy endocrine region, acquiring a titanium alloy implant region of the titanium alloy endocrine region;
The area obtained by subtracting the titanium alloy endocrine area from the titanium alloy implant area is used as a titanium alloy artifact area.
The method has the advantages that the distribution condition of annular closed edge textures in an endocrine region is analyzed to obtain titanium alloy texture degrees, the titanium alloy texture degrees better describe the outline of a titanium alloy implant, an initial titanium alloy endocrine region and a normal endocrine region are screened out according to the titanium alloy texture degrees, the distribution difference of the texture trend among the initial titanium alloy endocrine region, other surrounding initial titanium alloy endocrine regions and the normal endocrine region is compared to obtain titanium alloy tissue degrees, the titanium alloy tissue degrees enable the outline of an inflamed region caused by the titanium alloy implant in the initial titanium alloy endocrine region to be more obvious, the blurring condition of internal edge texture information of the initial titanium alloy endocrine region is analyzed according to the titanium alloy tissue degrees to obtain internal edge blurring degrees, the internal edge blurring degrees better reflect the complex distribution condition of the edge textures forming the closed annular region in the initial titanium alloy endocrine region, the method adaptively divides the artifact region generated by the inflamed region and other surrounding regions through the distribution relation between the analysis of the titanium alloy implant and body tissues, and the acquisition precision of an endocrine patient acquired medical image is improved.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flow chart of steps of a method for collecting and analyzing endocrine patient oriented medical images of the present invention;
FIG. 2 is a schematic view of a titanium alloy implant of the present invention;
FIG. 3 is a schematic representation of an MRI endocrine patient detection gray scale map of the present invention;
FIG. 4 is a schematic diagram of texture closure according to the present invention;
FIG. 5 is a schematic diagram of texture circularity according to the present invention;
FIG. 6 is a schematic view of a segment of the present invention;
FIG. 7 is a schematic illustration of the center-around concentration of the present invention.
Detailed Description
In order to further describe the technical means and effects adopted by the invention to achieve the preset aim, the following is a detailed description of specific implementation, structure, characteristics and effects of the method for collecting and analyzing the medical image of the endocrine patient according to the invention, which is provided by the invention, with reference to the accompanying drawings and the preferred embodiments. In the following description, different "one embodiment" or "another embodiment" means that the embodiments are not necessarily the same. Furthermore, the particular features, structures, or characteristics of one or more embodiments may be combined in any suitable manner.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
The following specifically describes a specific scheme of the endocrine patient-oriented medical image acquisition and analysis method provided by the invention with reference to the accompanying drawings.
Referring to fig. 1, a flowchart of a method for collecting and analyzing a medical image of an endocrine patient according to an embodiment of the invention is shown, the method includes the following steps:
Step S001, acquiring an MRI endocrine patient detection gray scale image, wherein the MRI endocrine patient detection gray scale image comprises a plurality of endocrine regions.
In the case of endocrine patients to which the titanium alloy implant is attached, various degrees of inflamed areas are generated between the corresponding titanium alloy implant and the body tissue due to individual differences of the endocrine patients, and the inflamed areas may form a certain degree of artifacts during the image acquisition by the Magnetic Resonance (MRI) technique, thereby interfering with the accuracy of acquiring medical images for the endocrine patients.
In a specific implementation mode of the embodiment of the invention, the method for acquiring the MRI endocrine patient detection gray level map and the endocrine region comprises the steps of acquiring an MRI detection image of an endocrine patient containing a titanium alloy implant in the body from an endocrine image library, carrying out gray level treatment on the MRI detection image to obtain the MRI endocrine patient detection gray level map, carrying out super-pixel segmentation on the MRI endocrine patient detection gray level map to obtain a plurality of super-pixel blocks, and taking each super-pixel block as the endocrine region. Referring to fig. 2, a schematic representation of a titanium alloy implant is shown, and referring to fig. 3, a schematic representation of an MRI endocrine patient detection gray scale is shown.
Specifically, the graying process and the super-pixel division are known techniques, and the description of this embodiment is omitted.
Thus, an MRI endocrine patient detection gray scale image and all endocrine regions are obtained through the method.
Step S002, analyzing the distribution condition of the edge textures in each endocrine region in a ring-shaped closed state to obtain the titanium alloy texture degree of each endocrine region, and screening a plurality of initial titanium alloy endocrine regions and a plurality of normal endocrine regions from all the endocrine regions according to the titanium alloy texture degree.
It should be noted that, in practical situations, the titanium alloy implant will be installed in different body tissues according to the body requirement of the endocrine patient, and the rejection of foreign substances such as the titanium alloy implant by different body tissues will be affected by the autoimmunity of the patient, the structure of the body tissues, and the like, so that the body tissues around the titanium alloy implant will have different degrees of inflamed areas, which will be distributed annularly around the titanium alloy implant, and the inflamed areas will be present as a closed area. Therefore, the distribution condition of the edge textures in each endocrine region in a ring-shaped closed state can be analyzed to obtain the titanium alloy texture degree of each endocrine region, and a plurality of initial titanium alloy endocrine regions and a plurality of normal endocrine regions are screened out from all the endocrine regions according to the titanium alloy texture degree. Wherein the greater the degree of texture of the titanium alloy, the more likely an inflamed region is present in the corresponding endocrine region due to the titanium alloy implant, reflecting the more likely an artifact is present in the corresponding endocrine region.
Preferably, in some implementation modes of the embodiment of the invention, the method for acquiring the texture degree of the titanium alloy comprises the steps of acquiring a plurality of initial titanium alloy edge textures in an endocrine region for any endocrine region, analyzing the distribution condition of the distances between adjacent initial titanium alloy edge textures to obtain the texture closure degree of the endocrine region, analyzing the direction extension change condition of the adjacent initial titanium alloy edge textures to obtain the texture circularity of the endocrine region, and obtaining the titanium alloy texture degree of the endocrine region according to the texture closure degree and the texture circularity, wherein the titanium alloy texture degree is positively correlated with the texture closure degree and positively correlated with the texture circularity. The specific process is as follows:
1. Obtaining initial titanium alloy edge textures.
And carrying out edge detection on the endocrine region to obtain a plurality of initial titanium alloy endocrine edge textures. In addition, the edge detection process is a well-known content of a Canny edge detection algorithm, and the embodiment is not repeated.
2. And obtaining the texture closure degree.
It should be noted that, due to the influence of the image acquisition device and the external environmental factors in the image acquisition process, the texture in the actual MRI endocrine patient detection gray scale image is composed of texture edges with different intervals. For any one endocrine region, if an artifact region generated by a titanium alloy implant exists in the endocrine region, the distance between partial texture edges exists in the endocrine region is smaller, so that a closed artifact region is formed. Therefore, the distribution condition of the distance between the adjacent initial titanium alloy edge textures can be analyzed, and the texture closure degree of the endocrine region can be obtained. Wherein the greater the degree of occlusion of the texture, the more likely the texture contained in the corresponding endocrine region is to be occluded. Referring to FIG. 4, a schematic diagram of texture closure is shown.
Preferably, in some implementation manners of the embodiment of the invention, the texture closure degree obtaining method comprises the steps of obtaining port distances between adjacent initial titanium alloy edge textures, and analyzing overall variation fluctuation conditions of the port distances between the adjacent initial titanium alloy edge textures to obtain the texture closure degree of the endocrine region. The specific process is as follows:
Taking a first pixel point and a last pixel point in each initial titanium alloy edge texture as texture end points, taking any two initial titanium alloy edge textures as target titanium alloy textures, taking the other initial titanium alloy edge texture as reference titanium alloy texture, obtaining the distance between each texture end point in the target titanium alloy texture and each texture end point in the reference titanium alloy texture, taking the minimum distance as the port distance between the target titanium alloy texture and the reference titanium alloy texture, obtaining the port distance between the target titanium alloy texture and the other initial titanium alloy edge textures, taking the initial titanium alloy edge texture with the minimum port distance between the target titanium alloy texture and the target titanium alloy texture as the adjacent titanium alloy texture of the target titanium alloy texture, taking the combination formed by the target titanium alloy texture and the adjacent titanium alloy texture as the adjacent titanium alloy edge combination, and obtaining all the adjacent titanium alloy edge combinations. Wherein each adjacent titanium alloy edge combination corresponds to a port distance, and each port distance corresponds to two pixel points.
Further, as an example, texture closure may be calculated by the following formula:
;
In the formula, Represent the firstTexture closure of individual endocrine regions; Represent the first Standard deviation of port distances for all adjacent titanium alloy edge combinations within each endocrine region; Representing preset super parameters, preset in this embodiment For preventing denominator from being 0; Represent the first The number of all adjacent titanium alloy edge combinations within each endocrine region; Represent the first Within the endocrine regionEdge combinations of adjacent titanium alloysAbsolute value of difference in port distance between adjacent titanium alloy edge combinations; representing an exponential function based on natural constants, the embodiments employ The model presents the inverse proportional relationship and the normalization process,For model input, the implementer may choose the inverse proportion function and the normalization function according to the actual situation.
It should be noted that, if the texture occlusion degree is larger, it is explained that there is a possibility that the texture region is occluded in the corresponding endocrine region.
3. And obtaining the circularity of the texture.
The artifact region may generate corresponding inflamed regions with different shapes according to factors such as the size and the shape of the titanium alloy implant, the edge textures of the inflamed regions may extend and change along different direction angles, and the shape of the edges of the region is annular, so that a closed region is finally formed. Therefore, the direction extension change condition of the adjacent initial titanium alloy edge textures can be analyzed, and the texture circularity of the endocrine region can be obtained. Wherein, if the texture circularity is larger, the edge change in the shape of a closed region in the corresponding endocrine region is more disordered, and the more likely that the corresponding endocrine region contains an inflammatory region is reflected. Referring to FIG. 5, a schematic diagram of texture circularity is shown.
Preferably, in some implementations of the embodiments of the present invention, the texture circularity obtaining method includes obtaining port degrees between adjacent initial endocrine edge textures, and analyzing a smooth offset condition of the port degrees between adjacent initial titanium alloy edge textures to obtain the texture circularity of the endocrine region. The specific process is as follows:
Taking any adjacent titanium alloy edge combination as an example, taking two pixel points corresponding to the port distance of the adjacent titanium alloy edge combination as a marked pixel point, taking the degree of an included angle between a line segment connected with the two marked pixel points and a horizontal line as the port degree of the adjacent titanium alloy edge combination, and obtaining the port degrees of all the adjacent titanium alloy edge combinations.
Further, as one example, texture circularity may be calculated by the following formula:
;
In the formula, Represent the firstTexture circularity of individual endocrine regions; Represent the first The number of all adjacent titanium alloy edge combinations within each endocrine region; Represent the first Within the endocrine regionEdge combinations of adjacent titanium alloysAbsolute value of the difference in port degrees between adjacent titanium alloy edge combinations.
The larger the texture circularity is, the more disordered the edge change in the shape of the closed region in the corresponding endocrine region is, reflecting that the more likely the inflamed region is contained in the corresponding endocrine region.
4. Obtaining the texture degree of the titanium alloy.
Taking a normalized value of the product between the texture closure degree and the texture circularity of the endocrine region as the titanium alloy texture degree of the endocrine region. Obtaining the texture degree of the titanium alloy in all endocrine areas.
In particular, the present embodiment usesThe normalization function is exemplified by normalization processing, wherein the normalization function can be determined according to specific implementation cases.
It is noted that, the greater the degree of texture of the titanium alloy, the more likely an inflamed region is present in the corresponding endocrine region due to the titanium alloy implant, reflecting the more likely an artifact is present in the corresponding endocrine region.
Further, presetting a titanium alloy texture degree threshold valueThe texture degree of the titanium alloy is larger than or equal toIs taken as an initial titanium alloy endocrine region, and the texture degree of the titanium alloy is smaller thanIs taken as a normal endocrine region. Wherein the present embodiment usesThe present embodiment is not specifically limited, and will be described by way of exampleDepending on the particular implementation.
So far, a plurality of initial titanium alloy endocrine regions and a plurality of normal endocrine regions are obtained by the method.
And S003, comparing grain trend distribution differences between the initial titanium alloy endocrine region and other surrounding initial titanium alloy endocrine regions and normal endocrine regions to obtain the titanium alloy tissue degree of each initial titanium alloy endocrine region.
It should be noted that, the possible presence of inflamed areas around the titanium alloy implant creates artifacts in the image, which, due to the complexity of the texture variations of the artifact itself, lead to the artifact having higher blurring characteristics, destroying the respective trend of the texture distribution of other tissue areas. Therefore, the grain trend distribution difference between the initial titanium alloy endocrine region and other surrounding initial titanium alloy endocrine regions and normal endocrine regions can be compared, and the titanium alloy tissue degree of each initial titanium alloy endocrine region can be obtained. Wherein the greater the degree of organization of the titanium alloy, the more likely the titanium alloy implant is present in the corresponding initial titanium alloy endocrine region, reflecting the more likely the corresponding initial titanium alloy endocrine region is to contain inflamed organization.
Preferably, in some implementation modes of the embodiment of the invention, the method for obtaining the titanium alloy tissue degree comprises the steps of taking any initial titanium alloy endocrine region as a target endocrine region, analyzing consistent distribution of grain trend between the target endocrine region and other surrounding normal endocrine regions to obtain normal neighborhood grain consistency degree of the target endocrine region, analyzing consistent distribution of grain trend between the target endocrine region and other surrounding initial titanium alloy endocrine regions to obtain titanium alloy neighborhood grain consistency degree of the target endocrine region, and obtaining the titanium alloy tissue degree of the target endocrine region according to difference between the normal neighborhood grain consistency degree and the titanium alloy neighborhood grain consistency degree. The specific process is as follows:
1. and obtaining the consistency of the normal neighborhood texture.
It should be noted that, since these artifact regions themselves destroy the texture distribution trend between the surrounding normal endocrine regions, the uniform distribution of the texture trend between the target endocrine region and other surrounding normal endocrine regions can be analyzed, so as to obtain the normal neighborhood texture uniformity of the target endocrine region. Wherein, if the texture consistency of the normal neighborhood is larger, the damage degree of the target endocrine region to the texture distribution of the surrounding normal body tissue is smaller.
Preferably, in some implementation manners of the embodiment of the invention, the method for obtaining the texture uniformity of the normal neighborhood comprises the steps of taking each normal endocrine region as a comparison normal endocrine region in a preset normal endocrine region range of the target endocrine region, obtaining a target texture fitting degree mean value of the target endocrine region, obtaining the texture fitting degree mean value of each comparison normal endocrine region, and comparing differences between the target texture fitting degree mean value and the texture fitting degree mean values of all the comparison normal endocrine regions to obtain the texture uniformity of the normal neighborhood of the target endocrine region. The specific process is as follows:
taking any endocrine region as an example, carrying out straight line fitting on each initial titanium alloy endocrine edge texture in the endocrine region to obtain a plurality of target edge fitting straight lines, taking the degrees of included angles between each target edge fitting straight line and a horizontal line as the degrees of texture fitting straight lines of each target edge fitting straight line, taking the average value of the degrees of the texture fitting straight lines of all target edge fitting straight lines as the average value of the degrees of the texture fitting straight lines of the endocrine region, and obtaining the average value of the degrees of the texture fitting straight lines of each endocrine region.
Further, an eight neighborhood region taking the target endocrine region as the center is used as a normal endocrine region range, each normal endocrine region is used as a comparison normal endocrine region in the normal endocrine region range, the texture fitting straight line degree mean value of the target endocrine region is used as a target texture fitting degree mean value, and the texture fitting straight line degree mean value of each comparison normal endocrine region is used as a texture fitting degree mean value. As one example, the normal neighborhood texture consistency may be calculated by the following formula:
;
In the formula, Representing the normal neighborhood texture consistency of the target endocrine region; All control normal endocrine regions representing target endocrine regions; representing a target texture fitting degree mean value of a target endocrine region; Represent the first Texture fitting degree averages of individual control normal endocrine regions; Representing preset super parameters, preset in this embodiment For preventing denominator from being 0; the representation takes absolute value.
It should be noted that, if the texture consistency of the normal neighborhood is greater, the damage degree of the target endocrine region to the texture distribution of the surrounding normal body tissue is smaller.
2. And obtaining the texture consistency of the titanium alloy neighborhood.
It should be noted that, after the grain distribution between the surrounding normal endocrine regions is destroyed, the grain distribution presented by the artifact regions is the grain distribution characteristic of the inflamed edge of the body tissue, and the initial titanium alloy endocrine region is an image region which may possibly have the inflamed edge of the tissue, so that the consistent distribution of the grain trend between the target endocrine region and other surrounding initial titanium alloy endocrine regions can be analyzed to obtain the titanium alloy neighborhood grain consistency of the target endocrine region. Wherein, if the texture consistency of the titanium alloy neighborhood is larger, the texture distribution mode in the target endocrine region is more similar to the texture distribution mode of surrounding inflamed tissues.
Preferably, in some implementation manners of the embodiment of the invention, the method for obtaining the titanium alloy neighborhood texture consistency comprises the steps of obtaining annular extension direction degrees of a target endocrine region within a preset initial titanium alloy endocrine region range of the target endocrine region, obtaining reference encircling extension direction degrees of each initial titanium alloy endocrine region, and analyzing the association condition of the annular extension direction degrees and the reference encircling extension direction degrees to obtain the titanium alloy neighborhood texture consistency of the target endocrine region. The specific process is as follows:
taking any initial titanium alloy endocrine region as an example, a line segment from the center of the initial titanium alloy endocrine region to the longest edge of the initial titanium alloy endocrine region in the initial titanium alloy endocrine region is taken as a regional direction line segment, the degree of an included angle between the regional direction line segment and a horizontal line is taken as an annular direction degree, and a schematic diagram of the regional direction line segment is shown in fig. 6.
Further, an eight-neighborhood region centered on the target endocrine region is taken as a titanium alloy endocrine region range, and each initial titanium alloy endocrine region is taken as a control titanium alloy endocrine region within the titanium alloy endocrine region range. The annular direction degree of each reference titanium alloy endocrine region is taken as the reference encircling extending direction degree, and the annular direction degree of the target titanium alloy endocrine region is taken as the annular extending direction degree.
The ranges of the endocrine region and the normal endocrine region in the present embodiment may or may not be identical in size.
Further, the average value of all the degrees of the encircling extension direction of the control is taken as the average value of the degrees of the extension direction of the control, and the absolute value of the difference value between the degrees of the annular extension direction and the average value of the degrees of the extension direction of the control is taken as the texture consistency of the alloy neighborhood of the target endocrine region.
It should be noted that, if the texture uniformity of the titanium alloy neighborhood is greater, the texture distribution pattern in the target endocrine region is more similar to the texture distribution pattern of surrounding inflamed tissues.
3. Obtaining the tissue degree of the titanium alloy.
And taking the absolute value of the difference between the alloy neighborhood texture consistency of the target endocrine region and the normal neighborhood texture consistency as the titanium alloy tissue degree of the target endocrine region.
It should be noted that, if the degree of the tissue of the titanium alloy is larger, it is indicated that the more likely the target endocrine region is to have the titanium alloy implant, the more likely the target endocrine region is to have inflamed tissue.
So far, the titanium alloy tissue degree of each initial titanium alloy endocrine region is obtained through the method.
And S004, analyzing the blurring condition of the internal edge texture information of the initial titanium alloy endocrine regions according to the titanium alloy tissue degree to obtain the internal edge blurring degree of each initial titanium alloy endocrine region.
It should be noted that, because the artifact is generated due to the possible inflamed area around the titanium alloy implant, the artifact is distributed along the titanium alloy implant at the approximate position of the image, so as to surround the titanium alloy implant, and meanwhile, the artifact reflects the blurring condition through the relatively complex disordered texture distribution, so that the blurring condition of the internal edge texture information of the internal edge of the internal endocrine region of the initial titanium alloy can be analyzed according to the tissue degree of the titanium alloy, and the internal edge blurring degree of each internal edge endocrine region of the initial titanium alloy can be obtained. And if the internal edge blurring degree is larger, the more complicated the edge texture distribution situation of the closed annular region formed in the corresponding initial titanium alloy endocrine region is, and the more likely an artifact region exists in the corresponding titanium alloy endocrine region is reflected.
Preferably, in some implementation manners of the embodiment of the invention, the method for acquiring the internal edge blurring degree comprises the steps of analyzing the distribution distances between different edge textures and the center of an initial titanium alloy endocrine region for any initial titanium alloy endocrine region to obtain the center surrounding concentration degree of the initial titanium alloy endocrine region, and analyzing the dispersion distribution condition between different edge textures according to the center surrounding concentration degree to obtain the internal edge blurring degree of the initial titanium alloy endocrine region. The specific process is as follows:
For any initial titanium alloy endocrine region, if an artifact region exists in the initial titanium alloy endocrine region, textures in the initial titanium alloy endocrine region can show a fuzzy sense in a manner of discrete distribution from a center point, so that distribution distances between different edge textures and the center of the initial titanium alloy endocrine region can be analyzed to obtain the center surrounding concentration of the initial titanium alloy endocrine region. And if the center surrounding concentration degree is larger, the degree of the edge texture distribution around the center surrounding in the corresponding initial titanium alloy endocrine region is larger, and the blurring effect reflecting the image information in the corresponding titanium alloy endocrine region is stronger.
Preferably, in some implementation manners of the embodiment of the invention, the center surrounding concentration is obtained by obtaining a center interval distance between each edge texture center and the center of the initial titanium alloy endocrine region in the initial titanium alloy endocrine region, obtaining the number of all edge texture centers, and obtaining the center surrounding concentration of the initial titanium alloy endocrine region according to the center interval distance and the number of the edge texture centers, wherein the center surrounding concentration is inversely related to the number of the edge texture centers. The specific process is as follows:
Taking a central point in each initial titanium alloy endocrine edge texture as an edge texture central point, taking the distance between each edge texture central point and the center of the initial titanium alloy endocrine region as a center interval distance, taking the average value of all center interval distances as an intermediate interval average value, and taking the ratio of the intermediate interval average value to the total number of all edge texture central points as the center surrounding concentration of the initial titanium alloy endocrine region. Referring to fig. 7, a schematic diagram of center-surround concentration is shown.
It should be noted that, if the center surrounding concentration is larger, the degree of the edge texture distribution around the center surrounding in the corresponding initial titanium alloy endocrine region is larger, and the blurring effect reflecting the image information in the corresponding titanium alloy endocrine region is stronger.
Further, the sequence obtained after all the center interval distances are arranged in a descending order is used as a center interval distance sequence, and the normalized value of the ratio between the standard deviation of all the center interval distances in the center interval distance sequence and the center surrounding concentration is used as the internal edge blurring degree of the initial titanium alloy endocrine region.
The greater the degree of blurring of the inner edges, the more complex the distribution of the edge texture constituting the closed loop region in the initial titanium alloy endocrine region, reflecting the greater the likelihood that the titanium alloy endocrine region has an artifact region.
So far, the internal edge blurring degree of each initial titanium alloy endocrine region is obtained through the method.
And step S005, dividing a titanium alloy artifact area from the initial titanium alloy endocrine area according to the internal edge blurring degree, and collecting and analyzing the MRI endocrine patient detection gray level image according to the titanium alloy artifact area.
Preferably, in some implementation manners of the embodiment of the invention, the acquisition method of the titanium alloy artifact region comprises the steps of screening a plurality of titanium alloy endocrine regions from all initial titanium alloy endocrine regions according to the internal edge blurring degree for any one initial titanium alloy endocrine region, acquiring a titanium alloy implant region of the titanium alloy endocrine region for any one titanium alloy endocrine region, and taking a region obtained by subtracting the titanium alloy endocrine region from the titanium alloy implant region as the titanium alloy artifact region. The specific process is as follows:
Presetting an internal edge blurring degree threshold value To blur the inner edge more thanAs the initial titanium alloy endocrine region. Taking any one titanium alloy endocrine region as an example, performing polygon fitting on initial titanium alloy endocrine edge textures in the titanium alloy endocrine region to obtain a polygon fitting region which is used as a titanium alloy implant region of the titanium alloy endocrine region, and taking an image region obtained by subtracting the titanium alloy endocrine region from the titanium alloy implant region as a titanium alloy artifact region of an MRI endocrine patient detection gray level chart. Wherein the present embodiment usesThe present embodiment is not specifically limited, and will be described by way of exampleDepending on the particular implementation. In addition, the polygon fitting is a well-known technique, and the description of this embodiment is omitted.
Further, if the titanium alloy artifact region does not exist in the MRI endocrine patient detection gray level image, marking the MRI endocrine patient detection gray level image as a normal MRI endocrine patient detection gray level image, storing the normal MRI endocrine patient detection gray level image in an image library with qualified image quality, marking the MRI endocrine patient detection gray level image as an abnormal MRI endocrine patient detection gray level image, and rearranging the MRI endocrine patient detection gray level image to carry out image acquisition and shooting again corresponding to an endocrine patient containing a titanium alloy implant in the body.
This embodiment is completed.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the invention, but any modifications, equivalent substitutions, improvements, etc. within the principles of the present invention should be included in the scope of the present invention.
Claims (5)
1. The medical image acquisition and analysis method for endocrine patients is characterized by comprising the following steps of:
Acquiring an MRI endocrine patient detection gray scale image, wherein the MRI endocrine patient detection gray scale image comprises a plurality of endocrine areas;
Analyzing the distribution condition of the edge textures in each endocrine region in a ring-shaped closed state to obtain the titanium alloy texture degree of each endocrine region;
Comparing grain trend distribution differences between the initial titanium alloy endocrine region and other surrounding initial titanium alloy endocrine regions and normal endocrine regions to obtain titanium alloy tissue degree of each initial titanium alloy endocrine region;
analyzing the fuzzy condition of the internal edge texture information of the initial titanium alloy endocrine region according to the titanium alloy tissue degree to obtain the internal edge fuzzy degree of each initial titanium alloy endocrine region;
Dividing a titanium alloy artifact region from the initial titanium alloy endocrine region according to the internal edge blurring degree, and collecting and analyzing an MRI endocrine patient detection gray level chart according to the titanium alloy artifact region;
The method for obtaining the titanium alloy texture degree comprises the steps of obtaining a plurality of initial titanium alloy edge textures in an endocrine region for any endocrine region, analyzing the distribution condition of distances between adjacent initial titanium alloy edge textures to obtain the texture closure degree of the endocrine region, analyzing the direction extension change condition of the adjacent initial titanium alloy edge textures to obtain the texture circularity of the endocrine region, and obtaining the titanium alloy texture degree of the endocrine region according to the texture closure degree and the texture circularity, wherein the titanium alloy texture degree is positively correlated with the texture closure degree and positively correlated with the texture circularity;
The method for obtaining the titanium alloy tissue degree comprises the steps of taking any initial titanium alloy endocrine region as a target endocrine region, analyzing consistent distribution of grain trend between the target endocrine region and other surrounding normal endocrine regions to obtain normal neighborhood grain consistency of the target endocrine region, analyzing consistent distribution of grain trend between the target endocrine region and other surrounding initial titanium alloy endocrine regions to obtain titanium alloy neighborhood grain consistency of the target endocrine region, and obtaining the titanium alloy tissue degree of the target endocrine region according to the difference between the normal neighborhood grain consistency and the titanium alloy neighborhood grain consistency;
The method for acquiring the internal edge blurring degree comprises the steps of analyzing the distribution distance between different edge textures and the center of an initial titanium alloy endocrine region for any initial titanium alloy endocrine region to obtain the center surrounding concentration degree of the initial titanium alloy endocrine region;
The texture closure degree obtaining method comprises the steps of obtaining port distances between adjacent initial titanium alloy edge textures, analyzing overall variation fluctuation conditions of the port distances between the adjacent initial titanium alloy edge textures, and obtaining the texture closure degree of an endocrine region;
the texture circularity obtaining method comprises the steps of obtaining port degrees between adjacent initial endocrine edge textures, and analyzing offset smooth conditions of the port degrees between the adjacent initial titanium alloy edge textures to obtain the texture circularity of an endocrine region.
2. The endocrine patient-oriented medical image acquisition and analysis method according to claim 1, wherein the method for acquiring the normal neighborhood texture consistency is as follows:
Taking each normal endocrine region as a comparison normal endocrine region in a preset normal endocrine region range of the target endocrine region, acquiring a target texture fitting degree mean value of the target endocrine region, and acquiring a texture fitting degree mean value of each comparison normal endocrine region;
Comparing the difference of the texture fitting degree mean value of the target and the texture fitting degree mean value of all the comparison normal endocrine regions to obtain the normal neighborhood texture consistency of the target endocrine regions;
The method comprises the steps of carrying out edge detection on an endocrine region to obtain a plurality of initial titanium alloy endocrine edge textures, carrying out straight line fitting on each initial titanium alloy endocrine edge texture in the endocrine region to obtain a plurality of target edge fitting straight lines, taking the included angle degrees of each target edge fitting straight line and a horizontal line as the texture fitting straight line degrees of each target edge fitting straight line, taking the average value of the texture fitting straight line degrees of all target edge fitting straight lines as the texture fitting straight line degree average value of the endocrine region, taking an eight neighborhood region taking the target endocrine region as the center as a normal endocrine region range, taking each normal endocrine region as a comparison normal endocrine region in the normal endocrine region range, taking the texture fitting straight line degree average value of the target endocrine region as a target texture fitting straight line degree average value, and taking the texture fitting straight line degree average value of each comparison normal endocrine region as the texture fitting straight line degree average value.
3. The method for acquiring and analyzing the medical image for the endocrine patient according to claim 2, wherein the method for acquiring the texture consistency of the titanium alloy neighborhood comprises the following steps:
Obtaining annular extension direction degrees of the target endocrine region in a preset initial titanium alloy endocrine region range of the target endocrine region;
analyzing the association condition of the annular extension direction degree and the contrast encircling extension direction degree to obtain the texture consistency of the titanium alloy neighborhood of the target endocrine region;
The annular extension direction degree acquisition method comprises the steps of regarding any initial titanium alloy endocrine region, regarding a line segment from the center of the initial titanium alloy endocrine region to the longest edge of the initial titanium alloy endocrine region as a regional direction line segment, regarding the degree of an included angle between the regional direction line segment and a horizontal line as an annular direction degree, regarding an eight neighborhood region with a target endocrine region as the center as a titanium alloy endocrine region range, regarding each initial titanium alloy endocrine region as a reference titanium alloy endocrine region in the titanium alloy endocrine region range, regarding the annular direction degree of each reference titanium alloy endocrine region as a reference circumferential extension direction degree, and regarding the annular direction degree of the target titanium alloy endocrine region as an annular extension direction degree.
4. The endocrine patient-oriented medical image acquisition and analysis method according to claim 1, wherein the central surrounding concentration obtaining method is as follows:
obtaining the center interval distance between each edge texture center and the center of the initial titanium alloy endocrine region in the initial titanium alloy endocrine region;
And obtaining the center surrounding concentration degree of the initial titanium alloy endocrine region according to the center interval distance and the number of the edge texture centers, wherein the center surrounding concentration degree is inversely related to the number of the edge texture centers.
5. The endocrine patient-oriented medical image acquisition and analysis method according to claim 1, wherein the acquisition method of the titanium alloy artifact region is as follows:
For any initial titanium alloy endocrine region, screening a plurality of titanium alloy endocrine regions from all initial titanium alloy endocrine regions according to the internal edge blurring degree;
for any one titanium alloy endocrine region, acquiring a titanium alloy implant region of the titanium alloy endocrine region;
The area obtained by subtracting the titanium alloy endocrine area from the titanium alloy implant area is used as a titanium alloy artifact area.
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