CN118750779B - Implantable medical device and wireless energy transmission method - Google Patents
Implantable medical device and wireless energy transmission method Download PDFInfo
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- 238000000034 method Methods 0.000 title abstract description 23
- 230000005540 biological transmission Effects 0.000 title abstract description 18
- 230000000638 stimulation Effects 0.000 claims abstract description 277
- 238000004146 energy storage Methods 0.000 claims description 47
- 238000004891 communication Methods 0.000 abstract description 27
- 230000008859 change Effects 0.000 abstract description 15
- 230000008878 coupling Effects 0.000 abstract description 10
- 238000010168 coupling process Methods 0.000 abstract description 10
- 238000005859 coupling reaction Methods 0.000 abstract description 10
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- 210000005036 nerve Anatomy 0.000 description 5
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- 210000001519 tissue Anatomy 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 210000000278 spinal cord Anatomy 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000008713 feedback mechanism Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000000578 peripheral nerve Anatomy 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
- A61N1/3787—Electrical supply from an external energy source
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
- A61N1/37223—Circuits for electromagnetic coupling
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Abstract
The application provides an implantable medical device and a wireless energy transmission method, wherein a receiving coil of the implantable medical device outputs alternating voltage, a rectifying circuit converts the alternating voltage into direct voltage, an electric stimulation module is provided with a first working state and a second working state, and a load balancing circuit controls a controllable load to be connected to an output end of the rectifying circuit under the condition that the electric stimulation module is in the second working state, and controls the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range. The controllable load is dynamically connected to the output end of the rectification circuit by controlling, so that when the electric stimulation module is switched between the first working state and the second working state, the load change of the implantable medical equipment is stable, the fluctuation of the reflection impedance of the transmitting end is reduced, the power amplifier of the transmitting end is ensured to output stable voltage signals, the error demodulation data output of the implantable medical equipment based on the coil pair coupling communication is avoided, and the effectiveness and the accuracy of the communication are improved.
Description
Technical Field
The application relates to the technical field of wireless energy transmission, in particular to implantable medical equipment and a wireless energy transmission method.
Background
There are two ways to supply power to the implantable medical device, one is battery powered, including disposable and rechargeable batteries, and the other is battery-less. The rechargeable battery and the implantable medical device without battery power supply usually adopt a coil pair coupling mode to transmit the electric energy of an external transmitting end to an implant receiving end, and the electric energy is rectified by a rectifying circuit and then is supplied to a battery management unit or an application circuit, wherein a transmitting coil of the transmitting end and a receiving coil of the implantable medical device form a coil pair.
In the case that the coil pair is used for both wireless energy transmission and communication, the load variation of the rectification circuit of the implanted medical device may affect the communication quality between the coil pair, especially at the time of outputting a pulse and the time of not outputting a pulse, for example, at the time of outputting a stimulation pulse and the time of not outputting a stimulation pulse of the implanted medical device such as a spinal cord nerve stimulator, a mini peripheral nerve stimulator, etc., the load after the rectification circuit is different and belongs to abrupt change, thereby affecting the effectiveness and accuracy of communication.
Disclosure of Invention
In view of the above, the present application provides an implantable medical device and a wireless energy transmission method to solve the deficiencies in the related art.
In a first aspect of the application, there is provided an implantable medical device comprising:
The receiving coil is used for receiving the energy sent by the sending coil of the sending end and outputting alternating voltage;
a rectifying circuit for converting the alternating voltage into a direct voltage;
the electric stimulation module is provided with a first working state and a second working state, and outputs stimulation pulses when in the first working state and does not output stimulation pulses when in the second working state;
And the load balancing circuit is used for controlling the controllable load to be connected to the direct-current output end of the rectifying circuit under the condition that the electric stimulation module is in the second working state, and controlling the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range, and the preset range is determined according to the power consumption of the electric stimulation module in the first working state.
According to one embodiment of the present application, the load balancing circuit includes:
The control unit is used for generating a control signal according to the working state of the electric stimulation module;
And the control end of the switching circuit receives the control signal, and the control signal is used for controlling the switching circuit to be conducted under the condition that the electric stimulation module is in the second working state so as to connect the controllable load to the direct current output end of the rectifying circuit.
According to one embodiment of the application, the electrical stimulation module comprises a storage unit for storing operating parameters of the electrical stimulation module, including the frequency, width and/or amplitude of stimulation pulses output by the electrical stimulation module;
The control unit is specifically configured to:
Acquiring the working parameters from the storage unit;
determining the working state of the electric stimulation module according to the working parameters;
And generating a control signal according to the working state of the electric stimulation module.
According to one embodiment of the application, the control signal comprises a pulse width modulated PWM wave, and the switching circuit comprises an NMOS transistor;
the NMOS tube is specifically used for:
And the grid electrode of the NMOS tube receives PWM waves, and the NMOS tube is conducted under the condition that the PWM waves are in a high level.
According to one embodiment of the application, the controllable load comprises at least one of a resistor array and a tank circuit.
According to one embodiment of the application, the energy storage circuit comprises an adjustable constant current source and an energy storage unit, wherein the adjustable constant current source is used for charging the energy storage unit;
The load balancing circuit is specifically configured to:
When the electric stimulation module is in the second working state, controlling the energy storage circuit to be connected with the direct current output end of the rectifying circuit;
and controlling the output current of the adjustable constant current source so that the sum of the power consumption of the energy storage circuit and the power consumption of the electric stimulation module is within the preset range.
In a second aspect of the present application, there is provided a wireless energy transmission method applied to an implantable medical device including a receiving coil, a rectifying circuit, an electro-stimulation module, a load balancing circuit, and a controllable load, the method comprising:
the receiving coil receives the energy sent by the sending coil of the sending end and outputs alternating voltage;
the rectification circuit converts the alternating voltage into direct voltage;
the electric stimulation module is provided with a first working state and a second working state, and outputs stimulation pulses when in the first working state and does not output stimulation pulses when in the second working state;
And the load balancing circuit controls the controllable load to be connected to the direct current output end of the rectifying circuit under the condition that the electric stimulation module is in the second working state, and controls the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range, and the preset range is determined according to the power consumption of the electric stimulation module in the first working state.
According to one embodiment of the application, the load balancing circuit comprises a control unit and a switching circuit, and when the electric stimulation module is in the second working state, the load balancing circuit controls the controllable load to be connected to the direct current output end of the rectifying circuit, and the load balancing circuit comprises:
The control unit generates a control signal according to the working state of the electric stimulation module;
The control end of the switching circuit receives the control signal, and the control signal is used for controlling the switching circuit to be conducted under the condition that the electric stimulation module is in the second working state so as to connect the controllable load to the direct current output end of the rectifying circuit.
According to one embodiment of the application, the electrical stimulation module comprises a storage unit for storing operating parameters of the electrical stimulation module, including the frequency, width and/or amplitude of stimulation pulses output by the electrical stimulation module;
the control unit generates a control signal according to the working state of the electric stimulation module, and the control signal comprises:
The control unit acquires the working parameters from the storage unit;
determining the working state of the electric stimulation module according to the working parameters;
And generating a control signal according to the working state of the electric stimulation module.
According to one embodiment of the application, the control signal comprises a Pulse Width Modulation (PWM) wave, the switch circuit comprises an NMOS tube, a control end of the switch circuit receives the control signal, and the control signal is used for controlling the switch circuit to be conducted under the condition that the electric stimulation module is in the second working state and comprises the following steps:
And the grid electrode of the NMOS tube receives PWM waves, and the NMOS tube is conducted under the condition that the PWM waves are in a high level.
According to one embodiment of the application, the controllable load comprises at least one of a resistor array and a tank circuit.
According to one embodiment of the application, the energy storage circuit comprises an adjustable constant current source and an energy storage unit, wherein the adjustable constant current source is used for charging the energy storage unit;
The controlling the controllable load to be connected to the direct current output end of the rectifying circuit, and controlling the controllable load to enable the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module to be within a preset range comprises the following steps:
Controlling the energy storage circuit to be connected to the direct current output end of the rectifying circuit;
and controlling the output current of the adjustable constant current source so that the sum of the power consumption of the energy storage circuit and the power consumption of the electric stimulation module is within the preset range.
According to the technical scheme, the receiving coil of the implantable medical device receives the energy output alternating current voltage sent by the sending coil of the sending end, the rectifying circuit converts the alternating current voltage into direct current voltage, the electric stimulation module is provided with a first working state and a second working state, the electric stimulation module outputs stimulation pulses under the condition of being in the first working state, the load balancing circuit does not output stimulation pulses under the condition of being in the second working state, the load balancing circuit controls the controllable load to be connected to the direct current output end of the rectifying circuit under the condition of being in the second working state, and controls the controllable load, so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range, and the preset range is determined according to the power consumption of the electric stimulation module under the first working state. The direct current output end of the rectification circuit is dynamically connected with the controllable load through control, so that when the electric stimulation module is switched between a first working state and a second working state, the load change of the implantable medical device is stable, fluctuation of reflection impedance of a transmitting end is reduced, the power amplifier of the transmitting end is ensured to output stable voltage signals, and further incorrect demodulation data output of the implantable medical device based on coil-to-coupled communication is avoided, and the effectiveness and accuracy of communication are improved.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application as claimed.
Drawings
FIG. 1 is a schematic view of an implantable medical device according to an embodiment of the present application;
FIG. 2 is a schematic diagram of a stimulation pulse and control signal provided by an embodiment of the present application;
Fig. 3 is a schematic diagram of a load balancing principle provided by an embodiment of the present application;
Fig. 4 is a schematic diagram of a load balancing principle provided by an embodiment of the present application;
fig. 5 is a schematic structural diagram of an extracorporeal transmitting end according to an embodiment of the present application;
Fig. 6 is a schematic flow chart of a wireless energy transmission method according to an embodiment of the present application;
Fig. 7 is a schematic structural diagram of an implantable medical device according to another embodiment of the present application.
Detailed Description
Reference will now be made in detail to exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, the same numbers in different drawings refer to the same or similar elements, unless otherwise indicated. The implementations described in the following exemplary examples do not represent all implementations consistent with the application. Rather, they are merely examples of apparatus and methods consistent with aspects of the application as detailed in the accompanying claims.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
In order to better understand the technical solution provided by the embodiments of the present application and make the above objects, features and advantages of the embodiments of the present application more obvious, the technical solution in the embodiments of the present application will be described in further detail below with reference to the accompanying drawings.
The rechargeable battery and the implantable medical device without battery supply often adopt a coil pair coupling mode to transmit the electric energy of the transmitting end to the receiving end of the implant, wherein the transmitting coil of the transmitting end and the receiving coil of the implantable medical device form a coil pair. However, in the case where the coil pair is used for both wireless energy transmission and communication, if the load after the rectifying circuit of the implantable medical device is significantly changed, the communication quality between the coil pair will be affected.
For example, the rectification circuit of the implantable medical device includes an electric stimulation module, wherein the electric stimulation module has a current of 0.1mA under the condition of not performing stimulation output, the current is continuous, and the electric stimulation module has a current of 4mA under the condition of performing stimulation output, a pulse width of 1ms and a period of 10ms. Thus, in a period of 10ms, there is a large current of 1ms and a small current of 9ms, and during the stimulation output of 1ms, the load is in a low-resistance state because a large current needs to be passed, and in a period of 9ms when the stimulation output is not performed, the load is in a high-resistance state because a small current passes, that is, the load after the rectifying circuit changes significantly in a certain period, and the load change affects the effectiveness and accuracy of the wireless communication of the implanted medical device based on the coil pair coupling.
Voltage fluctuations of the neurostimulator tend to interfere with the output waveform of the electrical stimulation, affecting the therapeutic effect of the electrical stimulation output of the neurostimulator. And the error code caused by the reduced communication accuracy can not timely acquire the working state of the nerve stimulator. The situation that the electric stimulation precision is higher than that of the electric stimulation precision implanted in the human body can cause great potential safety hazard to users.
In view of the above, the embodiment of the application discloses an implantable medical device, which controls a controllable load to be dynamically connected to a direct current output end of a rectifying circuit, so that when an electric stimulation module is switched between outputting a stimulation pulse (a first working state) and not outputting the stimulation pulse (a second working state), the power consumption consumed by the implantable medical device is stable, and the load change of the implantable medical device is stable, thereby reducing the fluctuation of reflection impedance of a transmitting end and ensuring that a power amplifier of the transmitting end outputs a stable voltage signal. Because the power amplifier at the transmitting end can output stable voltage signals, the direct-current voltage output by the rectifying circuit of the implanted medical equipment also tends to be stable, so that the therapeutic effect of the electric stimulation output of the nerve stimulator can be ensured. Meanwhile, the transmitting end power amplifier can output stable voltage signals, so that the error demodulation data output of the implanted medical equipment based on coil pair coupling communication can be avoided, the effectiveness and the accuracy of communication are improved, the error situation can be reduced under the condition that the effectiveness and the accuracy of the communication are improved, and the performance and the reliability of the nerve stimulator are improved.
As shown in fig. 1, fig. 1 is a schematic structural diagram of an implantable medical device according to an embodiment of the present application.
In embodiments of the present application, the implantable medical device may be a medical device that is fully or partially advanced into the interior of the human body by surgery or other medical means, and that is left in the body for a long period of time or temporarily after the end of the surgery, and may be used to treat, repair, or replace damaged tissues, organs, or functions of the human body.
Embodiments of the present application are not particularly limited in the type of implantable medical device that includes an electrical stimulation module that can output stimulation pulses. For example, the implantable medical device may include a neurostimulator (e.g., spinal cord neurostimulator, mini-peripheral neurostimulator, etc.), a cardiac defibrillator, etc.
As shown in fig. 1, the implantable medical device may include a receiving coil 110, a rectifying circuit 120, an electrical stimulation module 130, and a load balancing circuit 140.
The various parts of the implantable medical device are explained in detail below.
1. The receiving coil 110 is used for receiving the energy sent by the sending coil at the sending end and outputting alternating voltage.
In embodiments of the present application, the implantable medical device may communicate wirelessly with the extracorporeal transmit end as well as wirelessly based on the coupling of a pair of coils, where the pair of coils includes a receive coil 110 and a transmit coil of the transmit end of the implantable medical device. The receiving coil 110 can receive the energy transmitted by the transmitting coil at the transmitting end and output an ac voltage.
Illustratively, the receiving coil 110 and the transmitting coil of the transmitting end may include a resonant coil, a micro-helical coil, or other custom coils, and the type of receiving coil 110 and the transmitting coil of the transmitting end is not particularly limited in embodiments of the present application.
In some embodiments, the transmitting end may apply an ac voltage signal to the transmitting coil, and the change in the voltage waveform causes a corresponding change in the current in the transmitting coil, and the changed current may generate a changed magnetic field in space, where the changed magnetic field may propagate in the form of electromagnetic waves to the surrounding space. The receiving coil 110 senses a change in the magnetic field in the surrounding space and outputs an ac voltage.
In some embodiments, the implantable medical device further includes a resonant circuit, and after the receiving coil 110 receives the energy transmitted by the transmitting coil at the transmitting end and outputs an ac voltage, the ac voltage is transmitted to the resonant circuit, and the resonant circuit can adjust and optimize the frequency of the ac voltage to ensure that the frequency matches the resonant frequency of the receiving coil 110, thereby improving the energy conversion efficiency.
In some embodiments, the implantable medical device further includes an impedance matching circuit, the ac voltage processed by the resonant circuit is further transmitted to the impedance matching circuit, and the impedance matching circuit can adjust and optimize the impedance characteristics of the circuit, so as to ensure that the input impedance of the implantable medical device is matched with the characteristic impedance of the transmission line, reduce reflection and loss of energy in the transmission process, and further improve the energy conversion efficiency and stability of the overall system.
2. The rectifier circuit 120 is configured to convert the ac voltage into a dc voltage.
The rectifying circuit 120 is configured to rectify the ac voltage output from the receiving coil 110, and convert the ac voltage having a periodic positive-negative variation into a dc voltage having a single direction.
By way of example, the rectifying circuit 120 may include a half-wave rectifying circuit, a full-wave rectifying circuit (e.g., bridge rectifying), and the like.
In some embodiments, the implantable medical device further includes a filter circuit that may smooth the pulsating direct current voltage output by the rectifying circuit 120, reducing ripple in the voltage (i.e., the alternating current component of the voltage), thereby providing a more stable direct current voltage output.
In some embodiments, the implantable medical device further comprises a power network, which may include components such as a tank circuit, a power management circuit, etc., which may be used to store the rectified power from the rectification circuit 120, and a power management circuit, which may be used to monitor and distribute the rectified power from the rectification circuit 120.
3. The electrical stimulation module 130 has a first operating state and a second operating state, and outputs a stimulation pulse when in the first operating state and does not output a stimulation pulse when in the second operating state.
In an embodiment of the present application, the electric stimulation module 130 may work based on the dc voltage output by the rectifying circuit 120, where the working states of the electric stimulation module 130 include a first working state and a second working state, where the electric stimulation module 130 outputs a stimulation pulse when in the first working state, and the stimulation pulse may stimulate a human tissue or a nervous system, so as to achieve the purposes of treating, recovering or alleviating pain, and the like, and the electric stimulation module 130 does not output a stimulation pulse when in the second working state.
It will be appreciated that, in general, the electrical stimulation module 130 has low power consumption during the period when no stimulation pulse is output (i.e., the second operation state), and the current passing through the electrical stimulation module 130 is smaller, which represents a high-resistance load characteristic, and has high power consumption during the period when the stimulation pulse is output (i.e., the first operation state), and the current passing through the electrical stimulation module 130 is larger, which represents a low-resistance load characteristic, that is, the load after the rectifying circuit 120 changes due to the change of the operation state of the electrical stimulation module 130.
In some embodiments, electrical stimulation module 130 includes a memory unit for storing operating parameters of electrical stimulation module 130, including the frequency, width, and/or amplitude of the stimulation pulses output by electrical stimulation module 130;
Regarding the operation parameters, the operation parameters may be preset operation parameters, which may be stored in advance in the storage unit of the electrical stimulation module 130, for example, when the implantable medical device is shipped or initially configured, the preset operation parameters are written into the storage unit of the electrical stimulation module 130;
Or the working parameter can be a working parameter received by the implantable medical device in real time, and the implantable medical device and the transmitting end can be in wireless communication based on the coupling of the coil pair, so that the implantable medical device can receive the working parameter transmitted by the transmitting end in real time.
The operating parameters are used to control the electrical stimulation module 130 to output particular properties of the stimulation pulses, and in particular, the operating parameters may include the frequency, width, and/or amplitude of the stimulation pulses.
Where frequency refers to the number of stimulation pulses generated by the electrical stimulation module 130 per unit time, typically in hertz. For example, if the electrical stimulation module 130 is configured to generate 100 stimulation pulses per second, the frequency of the stimulation pulses in the operating parameter is 100Hz.
Width refers to the length of time each stimulation pulse lasts, typically in milliseconds. The width of the stimulation pulses determines the time of application of the stimulation pulses to the target tissue (e.g., nerve or muscle).
The amplitude refers to the intensity of the voltage or current of the stimulation pulse, which determines the intensity of the stimulation of the target tissue by the stimulation pulse.
4. And the load balancing circuit 140 is configured to control the controllable load to be connected to the dc output end of the rectifying circuit when the electrical stimulation module is in the second working state, and control the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electrical stimulation module is within a preset range, where the preset range is determined according to the power consumption of the electrical stimulation module in the first working state.
In the embodiment of the present application, the load balancing circuit 140 controls the controllable load to be connected to the dc output end of the rectifying circuit 120 under the condition that the electric stimulation module 130 does not output the stimulation pulse (i.e., the second working state), and controls the controllable load so that the sum of the controllable load and the power consumption of the electric stimulation module 130 is within a preset range, so that the implantable medical device can consume the electric energy rectified by the rectifying circuit 120 through the controllable load during the period that the electric stimulation module 130 does not output the stimulation pulse, and ensure that the load variation of the implantable medical device is stable during the period that the electric stimulation pulse is not output and the period that the stimulation pulse is output.
In some embodiments, the load balancing circuit 140 controls the controllable load not to be connected to the dc output of the rectifying circuit 120 when the electric stimulation module 130 is in the first operation state.
In some embodiments, the controllable load can be controlled according to actual requirements, so as to control and regulate the power consumption of the controllable load, wherein the controllable load comprises at least one of a resistor array and a tank circuit, and the controllable load can be the resistor array, the tank circuit or a combination of the tank circuit and the resistor array.
In some embodiments, load balancing circuit 140 may determine a preset range that is determined based on the power consumption of electrical stimulation module 130 in the first operating state, which may be determined by the operating parameters stored in the memory unit of electrical stimulation module 130.
For example, the operating parameters may include a frequency, a width, and an amplitude of the stimulation pulse, based on which the power consumption of the electrical stimulation module 130 in the first operating state may be estimated, and the load balancing circuit 140 may determine the preset range based on the power consumption value and the preset power consumption fluctuation threshold after obtaining the power consumption of the electrical stimulation module 130 in the first operating state. For example, the power consumption of the electrical stimulation module 130 in the first operating state is 0.2W, the preset power consumption fluctuation threshold is 0.02W, and the preset range may be determined to be greater than or equal to 0.18W and less than or equal to 0.22W.
In some embodiments, the load balancing circuit 140 may include a control unit and a switching circuit.
The control unit may generate a control signal according to the working state of the electrical stimulation module 130, and transmit the control signal to the control end of the switching circuit;
the control end of the switching circuit may receive a control signal from the control unit, where the control signal is used to control the switching circuit to be turned on when the electric stimulation module 130 is in the second working state, so as to connect the controllable load to the dc output end of the rectifying circuit 120, and to be turned off when the electric stimulation module 130 is in the first working state, so as not to connect the controllable load to the dc output end of the rectifying circuit 120.
By way of example, the control unit may include an MCU, digital control logic, etc., and the switching circuit may include an NMOS, PMOS, insulated gate bipolar transistor IGBT (Insulated gate bipolar transistor) switching circuit, etc.
Regarding the control unit, the control signal may be generated according to the operation state of the electrical stimulation module 130:
In some embodiments, electrical stimulation module 130 may include a memory unit for storing operating parameters of electrical stimulation module 130, including the frequency, width, and/or amplitude of the stimulation pulses output by electrical stimulation module 130. The control unit may obtain the above working parameters from the storage unit of the electrical stimulation module 130, determine the working state of the electrical stimulation module 130 according to the above working parameters, and generate the control signal according to the working state of the electrical stimulation module 130.
As shown in fig. 2, fig. 2 is a schematic diagram of a stimulation pulse and a control signal provided by the embodiment of the present application, where the electrical stimulation module 130 may generate the stimulation pulse shown in fig. 2 according to the working parameters in the storage unit, T1 is a period of time during which the electrical stimulation module 130 outputs the stimulation pulse, and T2 is an idle period after the stimulation pulse ends, that is, a period of time during which the electrical stimulation module 130 does not output the stimulation pulse.
The control unit may obtain the operation parameters from the storage unit of the electrical stimulation module 130, determine the operation state of the electrical stimulation module 130 according to the operation parameters, and generate the control signal shown in fig. 2 according to the operation state of the electrical stimulation module 130, where the period of the control signal is the same as the period of the stimulation pulse, t1=t3, t2=t4. The control signal is at a low level in a time T3, is at a high level in a time T4, and is turned off in a time T3 after the control signal is received by the control end of the switching circuit, that is, is turned off in a time when the electric stimulation module 130 outputs a stimulation pulse, and the controllable load is not connected to the dc output end of the rectifying circuit 120, and is turned on in a time T4, that is, is turned on in a time when the electric stimulation module 130 does not output a stimulation pulse, so as to connect the controllable load to the dc output end of the rectifying circuit 120.
The method for generating the control signal by the control unit according to the operation state of the electro-stimulation module 130 according to the embodiment of the present application is not particularly limited. For example, in some embodiments, the electrical stimulation module 130 may feedback its current operating state information to the control unit via a sensor or a state feedback mechanism (e.g., pin level, interrupt signal, etc.), and the control unit may generate a control signal, etc., based on the operating state of the electrical stimulation module 130.
The control terminal of the switching circuit may receive a control signal from the control unit, the control signal being configured to control the switching circuit to conduct when the electro-stimulation module 130 is in the second operation state:
in some embodiments, the control signal comprises a pulse width modulated PWM (Pulse Width Modulation) wave and the switching circuit comprises an NMOS tube.
A PWM wave is a periodic signal that consists of a series of high (typically 1 or logic high) and low (typically 0 or logic low) pulses.
The gate of the NMOS transistor may receive the PWM wave, and the NMOS transistor is turned on when the PWM wave is at a high level, so that the controllable load is connected to the dc output end of the rectifying circuit 120 when the electric stimulation module 130 does not output the stimulation pulse, and the NMOS transistor is turned off when the PWM wave is at a low level, so that the controllable load is not connected to the dc output end of the rectifying circuit 120 when the electric stimulation module 130 outputs the stimulation pulse.
The embodiment of the application is not particularly limited to the form of the control signal and the switch circuit, for example, the control signal can also comprise pulse code modulation PCM (Pulse Code Modulation) wave or other forms of signals with specific time sequence and duty ratio, and the switch circuit can comprise other types of switch elements such as PMOS (P-channel metal oxide semiconductor) tubes, IGBT (insulated gate bipolar transistor) and the like.
The preset range may be determined with respect to the load balancing circuit 140:
In some embodiments, the control unit may obtain the operation parameters from the storage unit of the electrical stimulation module 130, determine the power consumption of the electrical stimulation module 130 in the first operation state according to the operation parameters, and determine the preset range according to the power consumption of the electrical stimulation module 130 in the first operation state.
In the embodiment of the application, the receiving coil of the implantable medical device receives the energy output alternating voltage sent by the sending coil of the sending end, the rectifying circuit converts the alternating voltage into direct voltage, the electric stimulation module is provided with a first working state and a second working state, the electric stimulation module outputs stimulation pulses under the condition of being in the first working state, the load balancing circuit does not output stimulation pulses under the condition of being in the second working state, the load balancing circuit controls the controllable load to be connected to the direct current output end of the rectifying circuit under the condition of being in the second working state, and controls the controllable load so that the sum of the controllable load and the power consumption of the electric stimulation module is in a preset range, and the preset range is determined according to the power consumption of the electric stimulation module under the first working state. The direct current output end of the rectification circuit is dynamically connected with the controllable load through control, so that when the electric stimulation module is switched between a first working state and a second working state, the load change of the implantable medical device is stable, fluctuation of reflection impedance of a transmitting end is reduced, the power amplifier of the transmitting end is ensured to output stable voltage signals, and further incorrect demodulation data output of the implantable medical device based on coil-to-coupled communication is avoided, and the effectiveness and accuracy of communication are improved.
In some embodiments, the controllable load may be an energy storage circuit that may include an adjustable constant current source and an energy storage unit, wherein the adjustable constant current source is used to charge the energy storage unit.
Illustratively, the energy storage unit includes a capacitor, a battery, etc., which is not particularly limited by the embodiment of the present application.
In some embodiments, the load balancing circuit 140 may control the tank circuit to be connected to the dc output terminal of the rectifying circuit 120 when the electrical stimulation module 130 is in the second working state;
the output current of the adjustable constant current source is controlled so that the energy storage unit is charged by the output current of the adjustable constant current source, so that the sum of the power consumption of the energy storage circuit and the power consumption of the electric stimulation module 130 is within the preset range.
As shown in fig. 3, fig. 3 is a schematic diagram of a load balancing principle according to an embodiment of the present application, where the tank circuit includes an adjustable constant current source and an energy storage unit.
The control unit may generate a control signal according to the operation state of the electrical stimulation module 130, and transmit the control signal to the control terminal of the switching circuit.
The control end of the switching circuit can receive a control signal from the control unit, the control signal is used for controlling the switching circuit to be disconnected under the condition that the electric stimulation module 130 outputs stimulation pulses (namely, the first working state), and under the condition that the switching circuit is disconnected, the whole energy storage circuit is not connected to the direct current output end of the rectifying circuit, at the moment, the adjustable constant current source in the energy storage circuit can not charge the energy storage unit, no current passes through the energy storage circuit, and the energy storage circuit does not consume power consumption.
The control signal is further used for controlling the switch circuit to be turned on under the condition that the electric stimulation module 130 does not output stimulation pulses (i.e. the second working state), and under the condition that the switch circuit is turned on, the energy storage circuit is connected to the direct current output end of the rectifying circuit, so that the output current of the adjustable constant current source in the energy storage circuit can be controlled, the energy storage unit is charged by utilizing the output current of the adjustable constant current source, and meanwhile, the sum of the power consumption of the energy storage circuit and the electric stimulation module 130 is ensured to be within a preset range.
In the embodiment of the application, the direct current output end of the rectification circuit is dynamically connected through the control energy storage circuit, so that the power consumption consumed by the implantable medical device is stable when the electric stimulation module is switched between outputting stimulation pulses (namely a first working state) and not outputting stimulation pulses (namely a second working state), the load change of the implantable medical device is stable, the fluctuation of the reflection impedance of the transmitting end is reduced, the power amplifier of the transmitting end is ensured to output stable voltage signals, the error demodulation data output of the implantable medical device based on the coil pair coupling communication is avoided, and the effectiveness and the accuracy of the communication are improved.
Fig. 4 is a schematic diagram of a load balancing principle according to an embodiment of the present application, where the tank circuit includes an adjustable constant current source and an energy storage unit. The adjustable constant current source can output current for the stimulation output by the electric stimulation module 130 and current for charging by the energy storage unit.
The control unit may obtain the working parameters from the storage unit of the electrical stimulation module 130, determine the working state of the electrical stimulation module 130 according to the working parameters, generate the first control signal and the second control signal according to the working state of the electrical stimulation module 130, transmit the first control signal to the control end of the switching circuit, and transmit the second control signal to the control end of the stimulation channel switch.
In some embodiments, the control terminal of the stimulation channel switch receives a second control signal from the control unit, where the second control signal is used to control the stimulation channel switch to be turned on when the electrical stimulation module 130 needs to output a stimulation pulse (i.e., the first operating state), and where the adjustable constant current source may output a current that the electrical stimulation module 130 uses to perform stimulation output, so that the electrical stimulation module 130 outputs the stimulation pulse.
Under the condition that the stimulation channel switch is turned on, the control end of the switching circuit can receive a first control signal from the control unit, the first control signal is used for controlling the switching circuit to be turned off under the condition that the electric stimulation module 130 outputs stimulation pulses (namely, a first working state), and under the condition that the switching circuit is turned off, the energy storage unit cannot be charged by the adjustable constant current source in the energy storage circuit, no current passes through the energy storage circuit, and no power consumption is consumed by the energy storage circuit.
In some embodiments, the control terminal of the stimulation channel switch receives a second control signal from the control unit for controlling the stimulation channel switch to be turned off in case the electrical stimulation module 130 does not need to output the stimulation pulse (i.e. the second operation state), and in case the stimulation channel switch is turned off, the electrical stimulation module 130 cannot output the stimulation pulse.
When the stimulation channel switch is turned off, the control end of the switch circuit receives a first control signal from the control unit, the first control signal is used for controlling the switch circuit to be turned on under the condition that the electric stimulation module 130 does not output stimulation pulses (namely, the second working state), under the condition that the switch circuit is turned on, the output current of the adjustable constant current source in the energy storage circuit can be controlled, the energy storage unit is charged by using the output current of the adjustable constant current source, and at the moment, the current used for charging by the adjustable constant current source output energy storage unit can be equal to the current used for stimulating the output of the adjustable constant current source output electric stimulation module 130, so that the sum of the power consumption of the energy storage circuit (the power consumption during charging) and the power consumption during the period that the electric stimulation module 130 does not output stimulation pulses is equal to the power consumption during the period that the electric stimulation module 130 outputs stimulation pulses.
In the embodiment of the application, a control unit in a load balancing circuit can control a stimulation channel switch to be conducted when the electric stimulation module needs to output stimulation pulses according to working parameters stored in the electric stimulation module, and simultaneously control an energy storage circuit not to be connected to a direct-current output end of a rectifying circuit, so that an adjustable constant current source in the energy storage circuit cannot charge the energy storage unit, and control the stimulation channel switch to be disconnected when the electric stimulation module does not need to output stimulation pulses, and simultaneously control the energy storage circuit to be connected to the direct-current output end of the rectifying circuit, and charge the energy storage unit by utilizing the output current of the adjustable constant current source, so that the current consumed by the implantable medical device is unchanged when the electric stimulation module is switched between the output of the stimulation pulses (namely a first working state) and the non-output of the stimulation pulses (namely a second working state), thereby stabilizing the power consumption and the load change consumed by the implantable medical device, reducing fluctuation of reflection impedance of a transmitting end, ensuring that a power amplifier of the transmitting end outputs a stable voltage signal, and further avoiding error demodulation data output of the implantable medical device based on coil to couple communication, and improving the effectiveness and accuracy of communication.
As shown in fig. 5, fig. 5 is a schematic structural diagram of an external transmitting terminal according to an embodiment of the present application, where the external transmitting terminal may include a dc power supply circuit 510, a power amplifier 520, a signal modulation circuit 530, a high-frequency clock circuit 540, a signal demodulation circuit 550, a main control unit 560, and a resonant transmitting coil 570.
The dc power supply circuit 510 may provide a dc voltage and the dc voltage output therefrom may be adjustable, the adjustable voltage being output to the power amplifier 520, so that the output power of the power amplifier 520 may be adjusted.
The signal modulation circuit 530 receives the high frequency clock pulse generated by the high frequency clock circuit 540, and the signal modulation circuit 530 may adjust the high frequency clock pulse and then transmit the adjusted high frequency clock pulse to the power amplifier 520, thereby achieving a small-range adjustment of the output power of the power amplifier 520.
The power amplifier 520 amplifies the input signal according to the pulse width of the high frequency clock by the signal modulation circuit 530 and the dc voltage provided by the dc power supply circuit 510, and transmits the amplified input signal to the resonant transmitting coil 570, and finally, an Amplitude keying ASK (Amplitude SHIFT KEYING) modulated voltage waveform is displayed on the resonant transmitting coil 570, where the modulation depth can be determined by the pulse width of the high frequency clock and the dc voltage.
When an ASK modulated voltage waveform is applied to the resonant transmitting coil 570, the current in the resonant transmitting coil 570 will also change accordingly due to the change in the voltage waveform, and the changing current will generate a changing magnetic field in space, and the changing magnetic field can propagate in the form of electromagnetic waves to the surrounding space, thereby realizing wireless energy transmission or signal transmission.
The resonant transmit coil 570 may receive the communication signal transmitted by the implantable medical device and transmit the communication signal to the signal demodulation circuit 550. The signal demodulation circuit 550 performs demodulation processing on these communication signals, extracts target information, and transmits the target information to the main control unit 560 for further analysis and processing.
In embodiments of the present application, the implantable medical device may communicate wirelessly with the extracorporeal transmitting end and wirelessly based on the coupling of the coil pair.
Fig. 6 is a schematic flow chart of a wireless energy transmission method according to an embodiment of the application.
The wireless energy transmission method can be applied to an implantable medical device, which comprises a receiving coil, a rectifying circuit, an electric stimulation module, a load balancing circuit and a controllable load.
The wireless energy transmission method may include the steps of:
s601, the receiving coil receives energy sent by a sending coil of a sending end and outputs alternating voltage;
s602, the rectification circuit converts the alternating voltage into direct voltage;
S603, the electric stimulation module is provided with a first working state and a second working state, and outputs stimulation pulses when the electric stimulation module is in the first working state and does not output stimulation pulses when the electric stimulation module is in the second working state;
And S604, controlling the controllable load to be connected to the direct-current output end of the rectifying circuit by the load balancing circuit under the condition that the electric stimulation module is in the second working state, and controlling the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range, wherein the preset range is determined according to the power consumption of the electric stimulation module in the first working state.
Regarding the load balancing circuit:
In some embodiments, the load balancing circuit includes a control unit and a switching circuit;
the load balancing circuit controls the controllable load to be connected to the direct current output end of the rectifying circuit under the condition that the electric stimulation module is in the second working state, and the load balancing circuit comprises:
The control unit generates a control signal according to the working state of the electric stimulation module;
The control end of the switching circuit receives the control signal, and the control signal is used for controlling the switching circuit to be conducted under the condition that the electric stimulation module is in the second working state so as to connect the controllable load to the direct current output end of the rectifying circuit.
In some embodiments, the electrical stimulation module comprises a storage unit for storing operating parameters of the electrical stimulation module, the operating parameters including frequency, width, and/or amplitude of stimulation pulses output by the electrical stimulation module;
the control unit generates a control signal according to the working state of the electric stimulation module, and the control signal comprises:
The control unit acquires the working parameters from the storage unit;
determining the working state of the electric stimulation module according to the working parameters;
And generating a control signal according to the working state of the electric stimulation module.
In some embodiments, the control signal comprises a pulse width modulation PWM wave, the switch circuit comprises an NMOS tube, the control end of the switch circuit receives the control signal, the control signal is used for controlling the switch circuit to be conducted under the condition that the electric stimulation module is in the second working state, and the method comprises the following steps:
And the grid electrode of the NMOS tube receives PWM waves, and the NMOS tube is conducted under the condition that the PWM waves are in a high level.
Regarding the controllable load:
in some embodiments, the controllable load comprises at least one of a resistor array, a tank circuit.
The implementation process of each step in the wireless energy transmission method is specifically shown in the implementation process of the functions and actions of the corresponding part in the implantable medical device, and will not be repeated here.
Fig. 7 is a schematic structural view of an implantable medical device according to another embodiment of the present application, as shown in fig. 7. The implantable medical device may include a receiving coil, a resonant circuit, an impedance matching circuit, a rectifying circuit, a filtering module, a power network, an electrical stimulation module, a control unit, a switching circuit, a controllable load, a downstream demodulation module, and an upstream modulation module.
The implantable medical device may be in wireless energy transfer and wireless communication with an extracorporeal transmit end based on a coupling of a pair of coils, wherein the pair of coils includes a receive coil of the implantable medical device and a transmit coil of the transmit end.
The receiving coil receives energy sent by the sending coil at the sending end, outputs alternating voltage, the alternating voltage is transmitted to the resonant circuit, the resonant circuit can adjust and optimize the frequency of the alternating voltage so as to ensure that the alternating voltage is matched with the resonant frequency of the receiving coil, the alternating voltage processed by the resonant circuit can be further transmitted to the impedance matching circuit, and the impedance matching circuit can adjust and optimize the impedance characteristic of the circuit so as to ensure that the input impedance of the implantable medical device is matched with the characteristic impedance of the transmission line.
The rectification circuit converts the processed alternating voltage into direct voltage, the filtering circuit can smooth the pulsating direct voltage output by the rectification circuit, ripple waves (namely alternating current components in the voltage) in the voltage are reduced, and the power supply network stores, monitors and distributes the electric energy rectified by the rectification circuit.
The electric stimulation module comprises a storage unit, wherein the storage unit is used for storing working parameters of the electric stimulation module, and the working parameters comprise frequency, width and amplitude of stimulation pulses output by the electric stimulation module. The electric stimulation module can work based on the direct current voltage output by the rectifying circuit, and is in a first working state and a second working state according to working parameters, wherein the first working state comprises that the electric stimulation module outputs stimulation pulses, and the second working state comprises that the electric stimulation module does not output stimulation pulses.
The control unit obtains working parameters from the storage unit of the electric stimulation module, determines the working state of the electric stimulation module according to the working parameters, generates a control signal according to the working state of the electric stimulation module and transmits the control signal to the switch circuit, and can also determine the power consumption of the electric stimulation module in the first working state according to the working parameters and determine the preset range according to the power consumption of the electric stimulation module in the first working state.
The control end of the switching circuit receives a control signal, and the control signal is used for controlling the switching circuit to be conducted under the condition that the electric stimulation module is in a second working state (namely, the electric stimulation module does not output stimulation pulses) so as to connect the controllable load to the direct current output end of the rectifying circuit, and controlling the switching circuit to be disconnected under the condition that the electric stimulation module is in a first working state (namely, the electric stimulation module outputs stimulation pulses) so as not to connect the controllable load to the direct current output end of the rectifying circuit.
The control unit controls the controllable load after the controllable load is connected to the direct-current output end of the rectifying circuit, and controls and adjusts the power consumption of the controllable load, so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module in the second working state (namely, the electric stimulation module does not output stimulation pulses) is within a preset range.
The direct current output end of the rectification circuit is dynamically connected with the controllable load through control, so that when the electric stimulation module is switched between a first working state and a second working state, the load change of the implantable medical device is stable, fluctuation of reflection impedance of a transmitting end is reduced, the power amplifier of the transmitting end is ensured to output stable voltage signals, and further incorrect demodulation data output of the implantable medical device based on coil-to-coupled communication is avoided, and the effectiveness and accuracy of communication are improved.
It is noted that relational terms such as target and object, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises an element.
The foregoing description of the preferred embodiments of the application is not intended to be limiting, but rather to enable any modification, equivalent replacement, improvement or the like to be made within the spirit and principles of the application.
Claims (5)
1. An implantable medical device, comprising:
The receiving coil is used for receiving the energy sent by the sending coil of the sending end and outputting alternating voltage;
a rectifying circuit for converting the alternating voltage into a direct voltage;
the electric stimulation module is provided with a first working state and a second working state, and outputs stimulation pulses when in the first working state and does not output stimulation pulses when in the second working state;
The load balancing circuit is used for controlling a controllable load to be connected to the direct-current output end of the rectifying circuit under the condition that the electric stimulation module is in the second working state, and controlling the controllable load so that the sum of the power consumption of the controllable load and the power consumption of the electric stimulation module is in a preset range, and the preset range is determined according to the power consumption of the electric stimulation module in the first working state;
the load balancing circuit includes:
The control unit is used for generating a control signal according to the working state of the electric stimulation module;
And the control end of the switching circuit receives the control signal, and the control signal is used for controlling the switching circuit to be conducted under the condition that the electric stimulation module is in the second working state so as to connect the controllable load to the direct current output end of the rectifying circuit.
2. The implantable medical device according to claim 1, wherein the electrical stimulation module comprises a memory unit for storing operating parameters of the electrical stimulation module, the operating parameters comprising frequency, width and/or amplitude of stimulation pulses output by the electrical stimulation module;
The control unit is specifically configured to:
Acquiring the working parameters from the storage unit;
determining the working state of the electric stimulation module according to the working parameters;
And generating a control signal according to the working state of the electric stimulation module.
3. The implantable medical device according to claim 1, wherein the control signal comprises a pulse width modulated PWM wave and the switching circuit comprises an NMOS tube;
the NMOS tube is specifically used for:
And the grid electrode of the NMOS tube receives PWM waves, and the NMOS tube is conducted under the condition that the PWM waves are in a high level.
4. The implantable medical device according to claim 1, wherein the controllable load comprises at least one of a resistor array, a tank circuit.
5. The implantable medical device according to claim 4, wherein the energy storage circuit comprises an adjustable constant current source and an energy storage unit, wherein the adjustable constant current source is used to charge the energy storage unit;
The load balancing circuit is specifically configured to:
When the electric stimulation module is in the second working state, controlling the energy storage circuit to be connected with the direct current output end of the rectifying circuit;
and controlling the output current of the adjustable constant current source so that the sum of the power consumption of the energy storage circuit and the power consumption of the electric stimulation module is within the preset range.
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| EP2667942B1 (en) * | 2011-01-28 | 2019-10-23 | Micron Devices LLC | Neural stimulator system |
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| CN104821764B (en) * | 2015-04-23 | 2018-04-27 | 王金全 | A kind of power equivalent method of pulse load according to system dynamic characteristic |
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| US20230046820A1 (en) * | 2020-02-10 | 2023-02-16 | Nanovision Biosciences, Inc. | Apparatuses and methods for wirelessly powered charge-balanced electrical stimulation |
| CN112972895A (en) * | 2021-04-16 | 2021-06-18 | 北京领创医谷科技发展有限责任公司 | Implanted nerve stimulator |
| CN116726396A (en) * | 2023-06-13 | 2023-09-12 | 清华大学 | MRI compatible implantable electric stimulator system and working method thereof |
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