CN118526324A - Sealing skirt for heart valve, heart valve and preparation method - Google Patents

Abstract

The present invention discloses a sealing skirt for a heart valve, a heart valve and a preparation method. The sealing skirt can be arranged on the outside of the valve frame along the circumference of the valve frame. The sealing skirt includes a sealing skirt body and at least one sealing part arranged around the outside of the sealing skirt body. One edge of the sealing part is sealed and connected to the sealing skirt body in the circumference of the sealing skirt. The other edge of the sealing part is connected to the sealing skirt body at multiple mutually spaced positions along the circumference of the sealing skirt, so that the obtained sealing part has multiple pocket-shaped structures that are opened to the same side and are arranged in sequence in succession in the circumference of the sealing skirt, and the pocket-shaped structure can be stretched toward the side away from the valve frame under the action of the heart regurgitation blood. When regurgitation occurs, the pocket-shaped structure can be stretched under the pressure of the heart regurgitation blood, and a better sealing and matching effect can be obtained between the stretched pocket-shaped structure and the human body valve ring, thereby solving the problem of paravalvular leakage.

Description

Sealing skirt for heart valve, heart valve and preparation method

Technical Field

The present invention belongs to the technical field of medical devices, and in particular relates to a sealing skirt for a heart valve, a heart valve and a preparation method thereof.

Background Art

Transcatheter valve implantation is currently the main method for valve replacement therapy. It compresses the valve and loads it into a delivery catheter, delivers the valve to the desired implantation site through the delivery catheter, and then releases the valve from the delivery catheter to achieve the valve implantation operation.

Due to the differences in the human body's native structure at the valve implantation site, such as the irregular circumferential structure of the human valve annulus, it is often difficult for the periphery of the valve to form an effective seal with the human valve annulus, resulting in leakage around the valve, the so-called paravalvular leakage, which affects the performance of the valve and the effect of implantation.

Summary of the invention

The object of the present invention is to provide a sealing skirt for a heart valve, a heart valve and a preparation method thereof, so as to solve the problem of paravalvular leakage of the heart valve.

The present invention is achieved through the following technical solutions:

A sealing skirt for a heart valve, which can be arranged on the outside of a valve frame along the circumference of the valve frame, and comprises a sealing skirt body and at least one sealing portion arranged around the outside of the sealing skirt body, one edge of the sealing portion is sealedly connected to the sealing skirt body in the circumferential direction of the sealing skirt, and the other edge of the sealing portion is connected to the sealing skirt body at multiple mutually spaced positions along the circumference of the sealing skirt, so that the obtained sealing portion has multiple pocket-like structures opening to the same side and arranged in sequence in the circumferential direction of the sealing skirt, and the pocket-like structure can be stretched toward the side away from the valve frame under the action of cardiac reflux blood.

In some embodiments, the sealing portion is a multi-layer laminated structure.

In some embodiments, the sealing portion is a stacked structure in which each layer is continuously arranged in sequence.

In some embodiments, the sealing portion is obtained by folding the sealing skirt body at a certain position toward one end of the sealing skirt, and then connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt.

In some embodiments, the sealing portion is obtained by folding the sealing skirt body at a certain position to form a stacked sheet structure, then folding it toward one end of the sealing skirt, and connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt.

In some embodiments, the sealing skirt includes a plurality of sealing parts, which are arranged in sequence along the axial direction of the sealing skirt, and the openings of the pocket-shaped structures on each sealing part are arranged toward the same direction.

In some embodiments, the pocket-like structures of adjacent sealing parts are arranged in a staggered manner, so that in the axial direction of the sealing skirt, the openings of each pocket-like structure of one sealing part are located exactly at the joint position of two adjacent pocket-like structures on another sealing part.

On the other hand, the present invention also provides a method for preparing a sealing skirt, in which one edge of a sealing portion is sealingly connected to the sealing skirt body on the sealing skirt body, and the other edge of the sealing portion is connected to the sealing skirt body at multiple mutually spaced positions, so that a sealing portion having multiple pocket-like structures opening to the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-like structure of the sealing portion can be expanded toward the side away from the valve frame under the action of cardiac reflux blood.

In some embodiments, the sealing skirt body is folded at a certain position, and the free end of the folded portion is connected to the sealing skirt body at multiple positions to obtain the sealing portion.

In some embodiments, the sealing skirt body is folded at a certain position to form a stacked sheet structure and then folded, and the free end of the folded portion is connected to the sealing skirt body at multiple positions to obtain the sealing portion.

In some embodiments, a plurality of sealing portions are formed on the sealing skirt body along the axial direction of the sealing skirt.

On the other hand, the present invention also provides a heart valve, comprising a valve frame and the sealing skirt for the heart valve, and after the heart valve is implanted, the opening of the pocket-shaped structure of the sealing part is arranged toward the direction of cardiac regurgitation.

On the other hand, the present invention also provides a method for preparing a heart valve, wherein the sealing skirt is prepared by the above-mentioned preparation method, and then the prepared sealing skirt is connected to a valve frame.

In another aspect, the present invention further provides a method for preparing a heart valve, comprising:

Suturing the sealing skirt body to the valve frame along the circumference of the valve frame;

On the sealing skirt body, one edge of the sealing part is sealingly connected to the sealing skirt body, and the other edge of the sealing part is connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple mutually spaced positions by sutures, so that a sealing part having multiple pocket-shaped structures opening toward the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-shaped structures of the sealing part can be stretched toward the side away from the valve frame under the action of the heart regurgitation blood;

And/or, a plurality of sealing portions are formed on the sealing skirt body along the axial direction of the sealing skirt.

In some embodiments, the sealing skirt body is folded at a certain position, and the free end of the folded portion is sewn and connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple positions to obtain the sealing portion.

In some embodiments, including:

The sealing skirt body is folded at a certain position to form a laminated sheet structure and then folded, and the free end of the folded portion is sewn and connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple positions to obtain the sealing portion.

Compared with the prior art, the present invention has the following advantages and beneficial effects:

The present invention provides a sealing portion on the sealing skirt, and the sealing portion is configured as a structure of multiple pocket-shaped structures continuous in the circumferential direction. Since the pocket-shaped structures of the sealing portion have good continuity in the circumferential direction, the sealing skirt can form a good sealing fit with the human body's valve ring at each position in the circumferential direction; and when reflux occurs, the pocket-shaped structure can be expanded under the pressure of the heart's reflux blood, and a good sealing fit effect can be formed between the expanded pocket-shaped structure and the human body's valve ring, thereby effectively solving the problem of paravalvular leakage.

The sealing skirt in the present invention can be formed by sewing a piece of material as a whole, which is convenient to manufacture and form. The prepared sealing skirt can have good integrity and is convenient for connecting the sealing skirt to the heart valve, thereby facilitating the preparation of the heart valve.

The sealing part of the sealing skirt of the present invention adopts a multi-layer stacked structure, which makes the structure at the sealing part more fluffy, helps to form a better sealing fit between the sealing part and the human body valve ring, and has a better leak-proof effect.

The sealing skirt of the present invention is provided with a plurality of sealing parts, and adjacent sealing parts are arranged in a staggered manner. The sealing parts form a fish-scale structure on the sealing skirt, so that a good sealing effect can be obtained at each position of the sealing skirt in the circumferential direction.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

FIG1 is a schematic diagram of the structure of a heart valve in an embodiment of the present invention.

FIG. 2 is a front view of a local structure of a sealing skirt in an embodiment of the present invention.

Fig. 3 is a schematic cross-sectional view taken along the line A-A in Fig. 2 .

Fig. 4 is a schematic cross-sectional view taken along the line B-B in Fig. 2 .

FIG. 5 is a schematic diagram of the operation of the sealing skirt preparation process in an embodiment of the present invention.

FIG6 is a schematic cross-sectional view of the section C-C in FIG5 .

in:

10. Petal frame;

20. Sealing skirt, 21. Sealing skirt body, 22. Sealing part, 221. Connection point, 222. Pocket structure, 223. Joint.

DETAILED DESCRIPTION

In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments.

Referring to Figure 1, taking the heart valve structure as an example, a sealing skirt is provided on the periphery of the valve frame, so that when the valve is implanted, a sealing fit is formed between the sealing skirt and the human valve ring to solve the problem of paravalvular leakage. Usually, the valve frame is a regular annular structure in the circumferential direction. Although the elasticity of the valve frame can adapt to the structure of the human valve ring to a certain extent, which helps the fit between the periphery of the sealing skirt and the human valve ring, due to the irregular structure of the human valve ring, it is often difficult for the sealing skirt to form an effective sealing fit with the human valve ring at all positions in the circumferential direction, which leads to the problem of paravalvular leakage.

In order to obtain a better sealing effect, in some embodiments, the structure of the heart valve sealing skirt is designed. Referring to FIG. 1 , the sealing skirt 20 includes a sealing skirt body 21 circumferentially wrapped around the valve frame 10 and one or more sealing portions 22 surrounding the outside of the sealing skirt body.

The expressions involving circumferential and surrounding settings here are explained with reference to the installation state of the sealing skirt on the valve frame. With reference to the annular valve frame structure, "circumferential" refers to the circumferential direction along the valve frame, and "surrounding" setting refers to being set at least around the valve frame along the circumference of the valve frame; similarly, the "axial" mentioned later refers to the axial direction along the valve frame.

Referring to Figures 1 and 2, one edge of the sealing portion 22 is sealedly connected to the sealing skirt body 21 in the circumferential direction of the sealing skirt, and the other edge of the sealing portion 22 is connected to the sealing skirt body 21 at multiple mutually spaced positions along the circumferential direction of the sealing skirt. The sealing portion obtained by this connection method has multiple pocket-like structures 222 that are opened to the same side and are arranged continuously in sequence in the circumferential direction of the sealing skirt. The formed pocket-like structure 222 can be stretched toward the side away from the sealing skirt body (i.e., away from the valve frame) under the action of cardiac reflux blood.

It is easy to understand that the edge of this pocket-like structure at the open end is relaxed in a free state, and its side length is generally greater than the straight-line distance between its two end points, so that it can be better stretched when subjected to blood pressure.

The sealing skirt body and the sealing part can be made of the same material, which usually has a certain flexibility and deformation ability, so that it can be deformed when subjected to external force, so that it can form a good fit with the human body valve ring.

After the valve structure with this structural sealing skirt is implanted, when reflux occurs, the pocket-like structure can be expanded under the pressure of the reflux blood in the heart, so that the sealing part can better adapt to various irregular human valve ring structures. At this time, the sealing skirt and the human valve ring can achieve a better sealing effect, which effectively solves the problem of paravalvular leakage.

2, 5 and 6, the sealing portion 22 of this structure is equivalent to an annular pocket, except that the opening end of the annular pocket is connected by a plurality of spaced connection points 221 to divide it into a plurality of small pocket-like structures arranged in sequence.

Therefore, the characteristic of the sealing part in this sealing skirt is that the sealing part is arranged as a plurality of pocket-shaped structures which are continuous in the circumferential direction. By utilizing the structural characteristic of this continuity, there will be no leakage points at various positions in the entire circumferential direction, and a good sealing fit can be formed with the human valve ring at various positions.

It is easy to think that this sealing part can be made of a sheet, and one edge of the sheet is connected to the sealing skirt body, such as sewing connection, bonding connection, etc., so that the sealing part can form a good seal with the sealing skirt body at this position, and then the other edge of the sheet is connected to the sealing skirt body at multiple positions, and the sheet is connected to the sealing skirt body by stitches at each connection point. Since each connection point is spaced a certain distance apart, a pocket-like structure as shown in Figure 2 will be formed between two adjacent points. At this time, multiple pocket-like structures that are open to the same side and continuously arranged are formed on the sealing skirt body in the circumferential direction.

In some embodiments, the sealing portion 22 can be obtained by folding the sealing skirt body at a certain position toward one end of the sealing skirt, and then connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt. In this case, since one edge of the obtained sealing portion is directly obtained by folding, the connection operation at this position can be reduced during production, and since the entire sealing portion adopts an integrated structure, it can have good sealing performance at this position, and the sealing skirt has better integrity, and the production of the sealing skirt is simpler and more convenient.

In some embodiments, the folded portion of the sealing part can be arranged as a multi-layer stacking structure; for example, a matching sheet is added to the folded portion after folding to form a multi-layer stacking structure, or the folded portion is folded multiple times to obtain a stacking structure in which the layers are arranged continuously in sequence, and then the free edge of the folded portion of the stacking structure is connected to the sealing skirt body at multiple connection points through stitches. At this time, the obtained sealing part can form a fluffy effect in the radial direction, which can form a better fit between the sealing part and the human valve ring.

In some embodiments, referring to FIG. 5 and FIG. 6 , the sealing portion 22 can be obtained by folding the sealing skirt body at a certain position to form a laminated sheet structure, folding it toward one end of the sealing skirt, and then connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt. The sealing portion obtained at this time is a two-layer continuous laminated structure, which can make the sealing portion have a good fluffy effect. In addition, when making the sealing skirt, it is convenient to form multiple continuous sealing portions of this structure at multiple positions on a sealing skirt body, so that the sealing skirt has good integrity, as shown in FIG. 5 .

The sealing part with the above structure on the sealing skirt can solve the problem of paravalvular leakage well. When multiple sealing parts are arranged on the sealing skirt and the sealing parts are arranged in sequence along the axial direction of the sealing skirt, it is easy to understand that the arrangement of multiple sealing parts can better prevent paravalvular leakage caused by reflux. Of course, the openings of the pocket-shaped structures on each sealing part on the sealing skirt are all arranged in the same direction.

Taking the structure shown in FIG. 2 as an example, when the opening end of the sealing part 22 is connected to the sealing skirt body 21 at each connection point 221 by stitching, a pocket-shaped structure 222 is formed between two adjacent connection points 221. At the position corresponding to the two connection points on the sealing part 22, a joint 223 that fits the sealing skirt body is formed at this position due to the direct connection with the sealing skirt body, that is, a joint 223 is formed on both sides of each pocket-shaped structure 222 on the sealing part 22. Combined with the previous description, we know that the sealing part as a whole forms an annular pocket structure on the sealing skirt body. Under the action of the reflux pressure, when the pocket-shaped structure is stretched toward the side away from the sealing skirt body (that is, away from the valve frame), the position of the joint will be stretched toward the side away from the sealing skirt body (that is, away from the valve frame) at the same time, but the deformation amplitude of the stretching is smaller than that of the pocket-shaped structure.

That is to say, although the sealing part can play a certain sealing role at the joint position corresponding to each connection point, the sealing effect at this position is worse than the sealing effect at the pocket-shaped structure position. Providing multiple sealing parts 22 on the sealing skirt 20 can solve the sealing problem of the sealing part at this position to a certain extent. In order to achieve better effect, in some embodiments, the pocket-shaped structures 222 of the sealing parts arranged adjacent to each other along the axial direction of the sealing skirt are staggered, so that in the axial direction of the sealing skirt, the openings of each pocket-shaped structure 222 of one sealing part are exactly located at the joint position of two adjacent pocket-shaped structures 222 on another sealing part. As shown in Figure 2, the connection points 221 of adjacent sealing parts are staggered in the axial direction of the sealing skirt, and each connection point 221 on one sealing part is exactly located between two connection points 221 at the corresponding position of the other sealing part. At this time, the sealing part forms a fish-scale structure on the sealing skirt. In the axial direction of the sealing skirt, among the adjacent sealing parts, each pocket-like structure 222 of one sealing part is located exactly at a position corresponding to the joint 223 on another sealing part. In this way, a good sealing effect can be obtained at each circumferential position on the sealing skirt.

On the other hand, the present invention also relates to a method for preparing the sealing skirt in the above embodiment, which is used for preparing the sealing skirt.

Based on the different structures that the sealing skirt can adopt, in some embodiments, one edge of the sealing portion is sealed to the sealing skirt body on the sealing skirt body, and the other edge of the sealing portion is connected to the sealing skirt body at multiple mutually spaced positions, and a sealing portion having multiple pocket-like structures opening to the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-like structure of the sealing portion can be stretched toward the side away from the sealing skirt body (i.e., away from the valve frame) under the action of cardiac reflux blood.

In some embodiments, the sealing skirt body may be folded at a certain position, and the free end of the folded portion may be connected to the sealing skirt body at multiple positions to obtain the sealing portion.

In some embodiments, referring to Figures 3, 4, 5 and 6, the sealing skirt body can be pulled outward at a certain position and folded to form a stacked sheet structure, and then folded, and the free end of the folded part can be connected to the sealing skirt body at multiple positions to obtain the sealing portion.

In this embodiment, the above-mentioned manufacturing method can be further used to form a plurality of sealing portions arranged in sequence on the sealing skirt body along the axial direction of the sealing skirt when preparing the sealing skirt.

In the preparation method of the above embodiment, the connection between the pocket-shaped structure on the sealing part and the sealing skirt body at the open end can be connected by stitching, and the connection points of each sealing part are staggered. At this time, the sealing part can form a fish scale structure on the sealing skirt body as shown in Figure 2.

Based on the sealing skirt structure in the above embodiment, the present invention also relates to a heart valve. In some embodiments, referring to FIG1 , the heart valve includes a valve frame and the sealing skirt in the above embodiment, and after the heart valve is implanted, the opening of the pocket-shaped structure of the sealing portion is arranged toward the direction of cardiac regurgitation. Taking the mitral valve shown in FIG1 as an example, when the leaflets in the valve are opened, the end where blood flows in is the inflow end, and the end where blood flows out is the outflow end; cardiac regurgitation refers to blood flowing from the outflow end toward the inflow end, so in order to prevent regurgitation, the opening of the pocket-shaped structure is arranged toward the outflow end of the valve.

Of course, in other embodiments, the heart valve is not limited to the mitral valve shown in FIG. 1 , but may also be other types of artificial valves, such as a tricuspid valve.

The foregoing has clearly described the specific implementation methods of the sealing skirt preparation method. It should be further explained here that in the preparation of the heart valve, the sealing skirt can be made first, and after the sealing part is prepared on the sealing skirt, the prepared sealing skirt can be sewn to the valve frame, or the sealing skirt can be directly sewn on the valve frame while forming the sealing part on the sealing skirt.

In some embodiments, a method for preparing a heart valve comprises:

Suturing the sealing skirt body to the valve frame along the circumference of the valve frame;

One edge of the sealing portion is sealingly connected to the sealing skirt body on the sealing skirt body, and the other edge of the sealing portion is connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple mutually spaced positions by sutures, so that a sealing portion having multiple pocket-like structures opening to the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-like structure of the sealing portion can be stretched toward the side away from the sealing skirt body (i.e., away from the valve frame) under the action of cardiac reflux blood.

In this embodiment, when preparing the sealing skirt, a plurality of sealing portions which are sequentially arranged along the axial direction of the sealing skirt can be formed on the sealing skirt body.

In some embodiments, when preparing a heart valve, the sealing skirt body is folded at a certain position, and the free end of the folded portion is sutured and connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple positions to obtain the sealing portion.

In this embodiment, when preparing the sealing skirt, a plurality of sealing portions which are sequentially arranged along the axial direction of the sealing skirt can be formed on the sealing skirt body.

In some embodiments, when preparing a heart valve,

The sealing skirt body is pulled outward at a certain position and folded to form a stacked sheet structure, and then folded, and the free end of the folded part is sewn and connected to the sealing skirt body or the sealing skirt body and the valve frame at multiple positions to obtain the sealing part;

In this embodiment, when preparing the sealing skirt, a plurality of sealing portions which are sequentially arranged along the axial direction of the sealing skirt can be formed on the sealing skirt body.

In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. used to indicate the orientation or position relationship are based on the orientation or position relationship shown in the accompanying drawings, or are the orientation or position relationship commonly placed when the product of the invention is used. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

In addition, if the terms "horizontal" or "vertical" appear in the description of the present invention, it does not mean that the components are required to be absolutely horizontal or suspended, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any simple modification or equivalent change made to the above embodiment based on the technical essence of the present invention shall fall within the protection scope of the present invention.

Claims (16)

1. A sealing skirt for a heart valve, characterized in that the sealing skirt can be arranged on the outside of the valve frame along the circumferential direction of the valve frame, the sealing skirt comprises a sealing skirt body and at least one sealing portion arranged around the outside of the sealing skirt body, one edge of the sealing portion is sealed and connected to the sealing skirt body in the circumferential direction of the sealing skirt, and the other edge of the sealing portion is connected to the sealing skirt body at multiple mutually spaced positions along the circumferential direction of the sealing skirt, so that the obtained sealing portion has multiple pocket-like structures opening to the same side and arranged in sequence in the circumferential direction of the sealing skirt, and the pocket-like structure can be stretched toward the side away from the valve frame under the action of cardiac reflux blood. 2. The sealing skirt for a heart valve according to claim 1, characterized in that the sealing portion is a multi-layer laminated structure. 3. The sealing skirt for a heart valve according to claim 2, characterized in that the sealing portion is a stacked structure in which each layer is continuously arranged in sequence. 4. The sealing skirt for a heart valve according to claim 1 is characterized in that the sealing portion is obtained by folding the sealing skirt body toward one end of the sealing skirt at a certain position, and then connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt. 5. The sealing skirt for a heart valve according to claim 1 is characterized in that the sealing portion is obtained by folding the sealing skirt body at a certain position to form a stacked sheet structure, then folding it toward one end of the sealing skirt, and connecting the free end of the folded portion to the sealing skirt body at multiple positions along the circumference of the sealing skirt. 6. A sealing skirt for a heart valve according to any one of claims 1-5, characterized in that the sealing skirt comprises a plurality of sealing parts, the sealing parts are arranged in sequence along the axial direction of the sealing skirt, and the openings of the pocket-shaped structures on each sealing part are arranged in the same direction. 7. The sealing skirt for a heart valve according to claim 6 is characterized in that the pocket-like structures of adjacent sealing parts are staggered so that in the axial direction of the sealing skirt, the openings of each pocket-like structure of one sealing part are exactly located at the junction of two adjacent pocket-like structures on another sealing part. 8. A method for preparing a sealing skirt, characterized in that one edge of a sealing portion is sealingly connected to the sealing skirt body on the sealing skirt body, and the other edge of the sealing portion is connected to the sealing skirt body at a plurality of mutually spaced positions, so that a sealing portion having a plurality of pocket-like structures opening toward the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-like structure of the sealing portion can be stretched toward a side away from the valve frame under the action of cardiac reflux blood. 9. The method for preparing a sealing skirt according to claim 8, characterized in that the sealing skirt body is folded at a certain position, and the free end of the folded portion is connected to the sealing skirt body at multiple positions to obtain the sealing portion. 10. The method for preparing a sealing skirt according to claim 8 is characterized in that the sealing skirt body is folded at a certain position to form a stacked sheet structure and then folded, and the free ends of the folded parts are connected to the sealing skirt body at multiple positions to obtain the sealing portion. 11. The method for preparing a sealing skirt according to claim 8, 9 or 10, characterized in that a plurality of sealing portions are formed on the sealing skirt body along the axial direction of the sealing skirt. 12. A heart valve, characterized in that it comprises a valve frame and a sealing skirt for a heart valve according to any one of claims 1 to 7, and after the heart valve is implanted, the opening of the pocket-shaped structure of the sealing portion is arranged toward the direction of cardiac regurgitation. 13. A method for preparing a heart valve, characterized in that a sealing skirt is prepared by the preparation method according to any one of claims 8 to 11, and then the prepared sealing skirt is connected to a valve frame. 14. A method for preparing a heart valve, comprising: Suturing the sealing skirt body to the valve frame along the circumference of the valve frame; On the sealing skirt body, one edge of the sealing part is sealingly connected to the sealing skirt body, and the other edge of the sealing part is connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple mutually spaced positions by sutures, so that a sealing part having multiple pocket-shaped structures opening toward the same side and arranged in sequence is formed on the sealing skirt body, and the pocket-shaped structures of the sealing part can be stretched toward the side away from the valve frame under the action of the heart regurgitation blood; And/or, a plurality of sealing portions are formed on the sealing skirt body along the axial direction of the sealing skirt. 15. The method for preparing a heart valve according to claim 14 is characterized in that the sealing skirt body is folded at a certain position, and the free end of the folded portion is sutured and connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple positions to obtain the sealing portion. 16. The method for preparing a heart valve according to claim 14, characterized by comprising: The sealing skirt body is folded at a certain position to form a laminated sheet structure and then folded, and the free end of the folded portion is sewn and connected to the sealing skirt body or to the sealing skirt body and the valve frame at multiple positions to obtain the sealing portion.