CN118436402A - Human body lumen collection device, balloon catheter and thrombus removal device - Google Patents

Abstract

The invention relates to a collecting device in a human body lumen, a balloon catheter and a thrombus taking device, wherein the structure of the collecting device comprises a conveying device, a capturing net and a supporting device; the conveying device is tubular or filiform and is used for conveying the capturing net and the supporting device into the lumen of the human body; the capturing net comprises a first end and a second end, the first end is fixedly connected with the conveying device in a sealing way, and the second end is open and is used as an inlet of the capturing net; the capturing net is provided with an inner concave part, and the inner diameter of the inner concave part is smaller than the inner diameter of other sections of the capturing net; the support device is used for controlling the capturing net. According to the invention, the inner concave part is arranged on the capturing net, so that the overflow of collected thrombus, plaque and other fragments can be obviously reduced, when the collecting device is withdrawn, the supporting device is contracted, the inner concave part is closed first, the overflow of the fragments in the collecting device during contraction is reduced or avoided, the occurrence of adverse events is avoided, and the operation effect is ensured.

Description

Human body lumen collection device, balloon catheter and thrombus removal device

Technical Field

The present invention relates to the field of interventional medical technology, and in particular to a human body intraluminal collection device, a balloon catheter and a thrombus removal device.

Background technique

During vascular interventional treatment or the onset of an illness, plaques and blood clots often break off, which, along with blood circulation and flow, can cause vascular obstruction, leading to tissue necrosis or stroke.

During the operation of the shock wave balloon (also known as the shock wave balloon), when the shock wave destroys the calcified lesions, some emboli or plaque debris will be generated. If the generated debris is not cleared or cleared incompletely, the debris will flow with the blood to different parts of the body, causing new blockages or sequelae. Therefore, a collection device (protective device) is generally provided at the distal end of the shock wave balloon to collect and remove the generated debris. The general collection device is provided in the form of a net bag. When the shock wave balloon is working, the collection device at the distal end is in an expanded state. When the shock wave balloon smashes the calcified part, the knocked-down embolic debris flows with the blood or liquid and flows into the collection device. The collection device collects the generated debris or solids and fishes them out. In addition, a collection device can also be provided at the distal end of the thrombus removal device to collect and remove the thrombus debris or small thrombus blocks generated during the thrombus removal process.

After collecting the debris, the current collection device is generally deflated first and then withdrawn from the body through a catheter. During the deflation process, the debris collected in the collection device will be squeezed out, resulting in incomplete collection, which may cause postoperative complications to the patient.

Summary of the invention

The invention discloses a human body intraluminal collection device, a balloon catheter and a thrombus removal device, which are used to solve the technical problems existing in the prior art.

On the one hand, the present invention provides, in one embodiment, a human body intraluminal collection device, a human body intraluminal collection device, comprising a conveying device and a supporting device; the conveying device is axially arranged at the central axis of the human body intraluminal collection device, and the conveying device is used to convey the supporting device into the human body lumen; the supporting device comprises a plurality of expandable stents; one end of the expandable stent is fixedly connected to the second end, and the expandable stent can at least expand radially; one end of the expandable stent is slidably connected to the conveying device, at least one expandable stent has a smaller diameter than other expandable stents, and the expandable stent with a smaller diameter is arranged in the middle of the expandable stent with a larger diameter, so that the supporting device forms an inner recess.

As a preferred technical solution, a capture net; the supporting device is arranged in the capture net to control the capture net; the capture net includes a first end and a second end, the first end is sealed and fixedly connected to the conveying device, and the second end is open to serve as an entrance to the capture net; the first end and the second end are arranged opposite to each other at the axial ends of the capture net.

As a preferred technical solution, the supporting device includes a plurality of grids, which are in the shape of a net disk and can expand radially. The grids are fixedly connected to the inner side of the capture net for controlling the capture net; at least one end of the grid is slidably connected to the conveying device.

As a preferred technical solution, the first end and the second end of the capture net are both provided with the supporting device.

As a preferred technical solution, the edge of the second end of the capture net is provided with an outwardly extending portion, and the extending portion is in a skirt shape for contacting with the inner wall of the lumen.

As a preferred technical solution, it also includes a control line, the distal end of which is connected to the support device for controlling the radial expansion or contraction of the support device, and the proximal end of the control line is arranged along the axial direction of the conveying device and extends to the proximal end of the conveying device.

In another aspect, a human intraluminal collection device includes a delivery device, a capture net, and a support device;

The conveying device is tubular or filamentous and is axially arranged at the central axis of the collecting device in the human body lumen. The conveying device is used to convey the capture net and the supporting device into the human body lumen.

The capture net includes a first end and a second end, the first end is sealed and fixedly connected to the conveying device, and the second end is open and serves as an entrance of the capture net, and the first end and the second end are arranged at two axial ends of the capture net opposite to each other; the capture net is provided with an inner concave portion, which is configured as a waist-shaped variable diameter section, and the inner diameter of the inner concave portion is smaller than the inner diameter of other sections of the capture net;

The supporting device is arranged in the capturing net and is used for controlling the capturing net, wherein the controlling method of the capturing net includes but is not limited to supporting, contracting, expanding, opening and closing the capturing net.

As a preferred technical solution, multiple support devices are provided along the axial direction of the conveying device, and the outer diameter of the support device arranged in the inner recess is smaller than the outer diameter of the support device arranged at other positions, so that the inner recess is configured as a waisted variable diameter section.

As a preferred technical solution, the support device includes a plurality of grids, which are in the shape of a net disk and can be radially expanded. The grids are fixedly connected to the inner side of the capture net and are used to control the capture net;

At least one end of the grid is slidably connected to the conveying device.

As a preferred technical solution, the support device includes a plurality of expandable stents;

At least one expandable stent is disposed at the second end of the capture net, the distal end of the expandable stent is fixedly connected to the second end, and the expandable stent can at least expand radially to at least control the capture net; the proximal end of the expandable stent is slidably connected to the conveying device.

As a preferred technical solution, the supporting device includes a shape memory material.

As a preferred technical solution, at least one supporting device is disposed in the inner recess, and the supporting device is fixedly connected to the inner recess for controlling radial expansion and contraction of the inner recess.

As a preferred technical solution, both the first end and the second end of the capture net are provided with supporting devices.

As a preferred technical solution, it also includes a control line, the distal end of which is connected to the support device for controlling the radial expansion or contraction of the support device, and the proximal end of the control line is arranged along the axial direction of the conveying device and extends to the proximal end of the conveying device.

As a preferred technical solution, the conveying device is provided with a groove at a position corresponding to the capturing net, and the groove is sunken into the interior of the conveying device for accommodating debris.

As a preferred technical solution, the edge of the second end of the capture net is provided with an outwardly extending portion, which is in the shape of a skirt and is used to abut against the inner wall of the lumen.

As a preferred technical solution, a one-way membrane is provided inside the inner recess, the one-way membrane is umbrella-shaped, the large diameter end of the one-way membrane is connected to the inner recess, and the small diameter end of the one-way membrane is open and faces the first end of the capture net.

As a preferred technical solution, a layered inner net is further provided between the inner recess and the first end, and the layered inner net has a larger mesh size than the capture net.

On the other hand, the present invention provides a balloon catheter in one embodiment, comprising a human intraluminal collection device as described in any of the above items, and also comprising a balloon, which is arranged on a conveying device, and the balloon comprises an ordinary balloon, a shock wave balloon, a cutting balloon or a spinous process balloon.

On the other hand, the present invention provides, in one embodiment, a thrombus removal device, comprising the human intraluminal collection device as described in any one of the above items, and further comprising a catheter and/or a stent;

Catheters include common catheters, aspiration catheters, and thrombolytic catheters;

Stents include ordinary stents or thrombectomy stents.

The technical solution adopted by the present invention can achieve the following beneficial effects:

The embodiment of the present application provides an intraluminal collection device, in which the support device is arranged at the distal end of the delivery device, and the delivery device delivers the support device to the blood vessels in the human body, or other areas that need treatment. The support device includes a plurality of expandable stents; the diameter of the middle part of the expandable stent is small, forming an inner recess, so that the expandable stents at both ends embed the thrombus therein, and the inner recess in the middle can be used to accommodate the thrombus, etc., which is conducive to the removal of the thrombus.

The human body lumen collection device provided in the embodiment of the present application can significantly reduce the overflow of debris such as thrombus and plaque that have been collected by arranging an inner recess on the capture net. When the collection device is withdrawn, the supporting device contracts and the inner recess closes first, thereby reducing or avoiding the overflow of debris in the collection device during contraction, avoiding the occurrence of adverse events, and ensuring the surgical effect.

In addition, the above-mentioned collection device can be further arranged in a balloon catheter or a thrombectomy device, so as to provide a better debris collection effect in interventional procedures in multiple fields such as stone removal, cardiovascular and cerebrovascular thrombolysis, etc. in the respiratory system, digestive system, urinary system, reproductive system, ear canal, nervous system, and coronary arteries, cerebral arteries, lower limb arteries, lower limb veins, aortic arch, and valves in human blood vessels.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments, which constitute a part of the present invention. The exemplary embodiments of the present invention and their descriptions explain the present invention and do not constitute improper limitations on the present invention. In the drawings:

FIG1 is a stereoscopic view of a human body intraluminal collection device in a preferred embodiment disclosed in Example 1 of the present invention;

FIG2 is a schematic structural diagram of a human body intraluminal collection device in a preferred embodiment disclosed in Example 1 of the present invention;

FIG3 is a schematic structural diagram of a collection device in a human body lumen according to a preferred embodiment of the present invention disclosed in Example 1;

FIG4 is a schematic structural diagram of a collection device in a human lumen according to a preferred embodiment of the present invention disclosed in Example 1;

FIG5 is a schematic structural diagram of a human body intraluminal collection device in a preferred embodiment disclosed in Example 2 of the present invention;

FIG6 is a stereoscopic view of a collection device in a human lumen according to a preferred embodiment of the present invention disclosed in Example 2.

Description of reference numerals:

Catheter 100; capture net 200, first end 210, first section 211, second end 220, second section 221, inner recess 230, extension 240, layered inner net 250; grid 300, first grid 310, second grid 320, third grid 330; expandable stent 400, fulcrum 410; control line 500; unidirectional membrane 600.

Detailed ways

In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the specific embodiments of the present invention and the corresponding drawings. In the description of the present invention, it should be noted that the term "or" is usually used in the sense of including "and/or", unless the content clearly indicates otherwise.

In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or a magnetic connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be internal communication between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. In addition, in the description of this application, the terms "first", "second", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

In order to solve the problems existing in the prior art, an embodiment of the present invention provides a human body intraluminal collection device, including a conveying device, a capture net 200 and a supporting device; the conveying device is tubular or filamentary, and is axially arranged at the central axis of the human body intraluminal collection device, and the conveying device is used to convey the capture net 200 and the supporting device into the human body intraluminal; the capture net 200 includes a first end 210 and a second end 220, the first end 210 is sealed and fixedly connected to the conveying device, and the second end 220 is open, serving as an entrance of the capture net 200, and the first end 210 and the second end 220 are relatively arranged at the axial ends of the capture net 200; the capture net 200 is provided with an inner recess 230, and the inner recess 230 is configured as a waist-shaped variable diameter section in the axial direction of the capture net 200, and the inner diameter of the inner recess 230 is smaller than the inner diameter of other sections of the capture net 200; a plurality of supporting devices are arranged along the axial direction of the conveying device, and the supporting device is used to control the capture net 200.

Example 1

During vascular intervention, taking the use of shock wave balloon as an example, a pair or several pairs of discharge electrodes are placed in the balloon to form a set of shock wave generators, and then the electrodes are connected to the high-voltage pulse power supply host at the other end of the balloon catheter through wires. When the balloon is placed at the calcified lesion in the blood vessel, the host applies a high-voltage electric pulse to make the pressure wave generator in the balloon release shock waves. The shock waves can destroy the calcified lesions in the blood vessels and avoid damage to the blood vessels. However, when the shock wave destroys the calcified lesions, some emboli or plaque debris will be generated. At present, a net bag-like collection device can be used to collect the debris. However, when the collection device is withdrawn after surgery, the collection mesh needs to be contracted to reduce its volume and increase its permeability in the blood vessel. During the contraction process, the open collection device often squeezes out the collected debris, resulting in incomplete collection of the debris, which may cause postoperative complications to the patient.

Referring to Figures 1 to 4, in order to solve the problems existing in the prior art, this embodiment provides a human body lumen collection device for collecting thrombi or plaques broken by shock waves during interventional surgery. The structure of the human body lumen collection device includes a conveying device, a capture net 200 and a support device. The conveying device is configured as a tube or a filament, and is used to convey the capture net 200 into the human body lumen, and make the capture net 200 eventually reach the patient's lesion or other designated location. Preferably, the conveying device can be pre-set in the catheter passage in the blood vessel or other patient's pipeline; the support device is provided with multiple axially along the conveying device for supporting the capture net 200; one end of the capture net 200 is closed and fixed on the conveying device, and the other end is open, and the open end is used to collect debris.

Optionally, the delivery device can be configured as a guide wire or a catheter. Preferably, the delivery device is a catheter 100, which is arranged at the central axis of the collection device in the human body lumen, and can fix and transport the capture net 200 and the support device. On the one hand, the catheter 100 can reach the designated position in the patient's body under the guidance of the guide wire. On the other hand, after the guide wire is withdrawn, other interventional devices or structures can also be arranged in the catheter 100 cavity.

As shown in Figure 1, in a preferred embodiment, the capture net 200 is in the shape of a long net bag, and is divided into a first end 210 and a second end 220 along its length direction. The first end 210 is sealed and fixedly connected to the conveying device, and the second end 220 is open as the entrance of the capture net 200. The first end 210 and the second end 220 are relatively arranged at the two axial ends of the capture net 200.

Preferably, the capture net 200 is provided with an inner concave portion 230, which is configured as a waist-shaped variable diameter section, and the inner diameter of the inner concave portion 230 is smaller than the inner diameter of other sections of the capture net 200. Preferably, the inner concave portion 230 can make the capture net 200 have a radially inward contracted portion, so that the capture net 200 is not easy to overflow after collecting debris in the blood vessel cavity, and the inner concave portion 230 can play a role in blocking the debris collected by the capture net 200.

Those skilled in the art should understand that when the first end 210 is the distal end of the capture net 200, the second end 220 is the proximal end of the capture net 200; when the first end 210 is the proximal end of the capture net 200, the second end 220 is the distal end of the capture net 200; in a preferred embodiment, the distal end of the capture net 200 is configured as the first end 210, and the proximal end of the capture net 200 is configured as the second end 220. When in use, the capture net 200 should be set at the distal end of the shock wave balloon to collect debris and prevent the debris from escaping to the distal end.

As shown in Figure 2, preferably, the capture net 200 is divided into two sections with the inner recess 230 as the boundary, the section between the inner recess 230 and the first end 210 is the first section 211, and the section between the inner recess 230 and the second end 220 is the second section 221; preferably, the first section 211 is used to collect a larger amount of debris, when the entire capture net 200 is contracted, if the debris is squeezed out of the first section 211, the second section 221 can further collect the squeezed debris to play a double insurance role.

In a preferred embodiment, the axial length of the first section 211 is greater than the axial length of the second section 221 , so as to collect more debris.

Preferably, the maximum outer diameters of the first section 211 and the second section 221 should ensure at least an over-fit with the inner wall of the blood vessel cavity, and the two should match each other to prevent debris from escaping from the gap between the capture net 200 and the inner wall of the blood vessel; those skilled in the art should understand that since the shapes and sizes of blood vessels are different in different patients or different lesion areas in the same patient, it can be understood that the size of the capture net 200, the length of the first section 211 and the second section 221, and the length and outer diameter of the inner recess 230 can be adaptively changed according to the actual situation of the patient.

Specifically, although the capture net 200 is artificially divided into the first section 211, the second section 221 and the inner recess 230, it should be noted that the three sections are integrally formed with smooth transitions, and the capture net 200 can have the aforementioned three sections through different weaving methods or weaving clamps.

Preferably, the capture net 200 is woven from metal or elastic fibers, and the specific weaving method is not specifically limited in this embodiment.

In a preferred embodiment, a support device is provided at least at the entrance and the inner recess 230 of the capture net 200, and the entrance and the inner recess 230 of the capture net 200 can be opened and closed by controlling the radial expansion or contraction of the support device. It should be understood by those skilled in the art that when the capture net 200 is expanded, it is supported by the support device to achieve expansion, and when the capture net 200 is contracted, it is also radially contracted by the contraction of the support device. Taking the second section 221 as an example, after the second section 221 is expanded, its maximum diameter is the outer diameter of the support device provided at the entrance (ignoring the thickness of the capture net 200); taking the inner recess 230 as an example, after the inner recess 230 is expanded, its maximum diameter is the outer diameter of the support device provided at the inner recess 230.

In a preferred embodiment, the human intraluminal collection device also includes a control line 500, the distal end of which is connected to the support device for controlling the radial expansion or contraction of the support device, and the proximal end of the control line 500 is arranged along the axial direction of the conveying device and extends to the proximal end of the conveying device.

Preferably, when the capture net 200 is retracted and withdrawn, the support device arranged at the inner recess 230 is retracted first through the control line 500, so that the inner recess 230 can be closed before the entrance, thereby reducing or avoiding the overflow of debris collected therein when the capture net 200 is retracted. If some debris still overflows at this time, these overflowed debris will enter the second section 221, and the support device arranged at the entrance of the capture net 200 is retracted through the control line 500, thereby further preventing the debris collected in the second section 221 from overflowing.

In a preferred embodiment, at least two control lines 500 control two different support devices, which can realize the separate control of the closing and opening of the support devices, and can control the closing of the capture net 200 according to the situation, so that the capture net 200 can be controlled more flexibly.

In a preferred embodiment, the supporting device is configured as a plurality of grids 300, which are in the shape of a mesh disk and can expand radially. The grids 300 are fixedly connected to the inner side of the capture net 200 to support the capture net 200; preferably, at least one end of the grid 300 is slidably connected to the conveying device.

Optionally, the mesh 300 may be made of shape memory metal materials or other materials that do not have shape memory properties; when the mesh 300 is made of shape memory metal materials, nickel-titanium alloy may be used. After the mesh 300 is delivered to a specified position, it can radially expand to a prefabricated shape, and can be controlled to shrink by withdrawing the control line 500; when the mesh 300 is made of materials that do not have shape memory properties, medical stainless steel or cobalt-chromium alloy may be used. After the mesh 300 is delivered to a specified position in the blood vessel cavity, the mesh 300 can be radially expanded by extending the control line 500 toward the distal end, and its radial shrinkage can be achieved by withdrawing the control line 500 toward the proximal end.

In a preferred embodiment, considering that the structural strength of the control line 500 may not be sufficient to allow the grid 300 to expand radially, the grid 300 is made of a shape memory alloy. Furthermore, the shape memory alloy material has a certain elasticity and can undergo elastic deformation, thereby ensuring that the grid 300 can maintain a good fit with the inner wall of the blood vessel cavity during radial expansion, so as to further increase the efficiency of debris collection in the blood vessel and avoid the occurrence of debris escape.

As shown in Figure 2, preferably, the human body intraluminal collection device includes a first grid 310, a second grid 320 and a third grid 330, the first grid 310 is arranged at the first section 211 of the capture net 200, the second grid 320 is arranged at the entrance of the capture net 200, and the third grid 330 is arranged at the inner recess 230 of the capture net 200; more preferably, the outer diameter of the third grid 330 is smaller than the outer diameters of the first grid 310 and the second grid 320 to form the inner recess 230 of the capture net 200, thereby reducing the overflow of debris collected in the first section 211; more preferably, the outer diameter of the first grid 310 matches the inner diameter of the blood vessel cavity, and the first grid 310 supports the entrance of the capture net 200, so that the entrance of the capture net 200 can fit the blood vessel wall as closely as possible to collect debris to the greatest extent.

Optionally, the opening of the entrance of the capture net 200 can be achieved by directly controlling the radial expansion of the first grid 310, or the expansion of the entrance of the capture net 200 can be achieved after the first grid 310, the second grid 320 and the third grid 330 are all expanded.

In a preferred embodiment, the distal ends of the first grid 310, the second grid 320 and the third grid 330 are fixed on the conveying device, and the proximal ends are slidably connected to the conveying device. The number of control wires 500 is configured as one, and its distal ends are respectively fixed to the proximal ends of the three grids 300. The proximal end of the control wire 500 extends to the control end of the doctor's handle. The doctor controls the operating handle to retract the control wire 500, so that the first grid 310, the second grid 320 and the third grid 330 shrink at the same time.

In another preferred embodiment, the distal ends of the first grid 310, the second grid 320 and the third grid 330 are fixed on the conveying device, and the proximal ends are slidably connected to the conveying device. The number of control lines 500 is configured to be three, and the three control lines 500 are respectively connected to the proximal ends of the three grids 300. After the capture net 200 has collected the debris or the operation is completed, the doctor selectively controls the expansion and contraction of different grids 300 by controlling different buttons on the operating handle. Preferably, after the operation is completed, the third grid 330 is first contracted to seal the debris in the first section 211, and then the second grid 320 is contracted to prevent a small amount of debris overflowing from the first section 211 from further overflowing from the second section 221 outside the capture net 200. Finally, the contraction of the first grid 310 is controlled, and the contraction degree of the first grid 310 can be selectively controlled according to the volume of the debris collected by the first section 211 to ensure that the debris has enough retention space and avoid excessive squeezing of the debris by the first section 211 to cause its escape.

Preferably, the mesh size of the second grid 320 and the third grid 330 should be set to allow larger debris to pass through, while the mesh size of the first grid 310 can allow debris to pass through, and can also be set to not allow debris to pass through.

Optionally, in this embodiment, the number of grids 300 can be determined according to the size and axial length of the capture net 200 , but at least grids 300 need to be set in the inner recess 230 and the entrance of the capture net 200 .

As shown in FIG4 , in a preferred embodiment, the edge of the entrance of the capture net 200 is provided with a radially outward extension 240, which is arranged along the circumference of the entrance and is in the shape of a skirt, and is used to abut against the inner wall of the blood vessel cavity, so that the entrance of the capture net 200 can fit more closely with the inner wall of the blood vessel cavity, and prevent debris from escaping through the gap between the entrance and the blood vessel wall, ensuring that all debris can be collected by the collection device in the human body lumen. Optionally, the skirt is made of a biopolymer material, such as a biohydrogel or a medical sealing film.

Preferably, the entrance of the capture net 200 is inclined, and the angle between the entrance and the inner wall of the blood vessel cavity is not equal to 90°, so that the entrance can be open to facilitate the entry of debris.

As shown in Figure 4, preferably, a one-way membrane 600 is provided on the inner side of the entrance of the capture net 200, the one-way membrane 600 is in an umbrella shape, and the large diameter end of the one-way membrane 600 is connected to the entrance, and the small diameter end of the one-way membrane 600 is open and faces the first end 210 of the capture net 200; more preferably, the one-way membrane 600 is arranged on the inner side of the inner recess 230 and is in an umbrella shape, the large diameter end of the one-way membrane 600 is connected to the inner recess 230, and the small diameter end of the one-way membrane 600 is open and faces the first end 210 of the capture net 200.

Specifically, the opening of the one-way membrane 600 is set in the same direction as the blood flow direction. When debris escapes in the collection device in the human body lumen in the reverse direction, the one-way membrane 600 can be closed to prevent the debris from escaping offline.

Specifically, the unidirectional membrane 600 is made of a biopolymer material, and specifically can be made of the same material as the extension portion 240; the structure of the unidirectional membrane 600 can refer to an artificial heart valve, and is composed of two or three leaflets arranged along the circumference of the capture net 200. When collecting debris, the multi-leaflet leaflets can be opened like an artificial heart valve and allow debris to enter; after the debris is collected, the capture net 200 is contracted by the control line 500, and the multi-leaflet leaflets can be passively closed when subjected to the reverse impact of the debris, thereby preventing debris from overflowing.

As shown in Figure 3, in a preferred embodiment, a layered inner net 250 is further provided between the inner recess 230 and the first end 210. The layered inner net 250 has a larger mesh size than the capture net 200, so that large debris can stay on the layered inner net 250, and small debris can pass through the layered inner net 250 to reach the first section 211; the layered inner net 250 can layer debris of different sizes, so that debris of different sizes are distributed at different positions of the capture net 200, to avoid the debris gathering in one part and causing temporary blockage of blood vessels or other lumens.

Specifically, the layered inner net 250 can be woven using the same material as the capture net 200, and the layered inner net 250 and the capture net 200 are fixedly connected by sewing.

In a preferred embodiment, the conveying device is provided with a groove at a position corresponding to the capturing net 200, and the groove is sunken into the interior of the conveying device for accommodating debris and increasing the passability of the collection device in the human body lumen.

Specifically, the grooves may be regularly arranged on the delivery device in a matrix pattern, or may be staggered. When the grooves are arranged on the delivery device, the delivery device is a catheter 100 instead of a guidewire.

In this embodiment, the above-mentioned human body lumen collection device can be transported to the distal end of the lesion through the lumen of the guide wire, guide catheter or shock wave balloon when in use. The shock wave balloon releases shock waves to destroy the calcified lesions in the blood vessels. At the same time, the emboli or plaque debris generated by the lesions flow to the distal end with the blood flow and enter the capture net 200 of the human body lumen collection device. After the operation is completed, the shock wave balloon can be withdrawn or not, and then the mesh frame 300 of the inner concave portion 230 of the capture net 200 is first contracted by withdrawing the control line 500 to minimize the risk of bleeding. It can prevent debris from escaping from the first section 211 of the capture net 200 (with the impact of blood flow, most of the debris gathers in the first section 211), and then withdraw another control line 500 to shrink the grid 300 at the entrance of the capture net 200 to prevent a small amount of debris from escaping from the second section 221. If grids 300 are provided at other positions of the capture net 200, they can be shrunk one by one through the control line 500 to make the entire capture net 200 radially shrink and axially stretch, and then be withdrawn from the body through the lumen of the guide catheter or shock wave balloon, and the operation is completed.

Those skilled in the art should understand that the application scenario in the blood vessel cavity provided in this embodiment is only an example. In fact, the above-mentioned collection device in the human lumen can be applied to interventional surgeries in the reproductive system, digestive system, urinary system, ear canal, nervous system and coronary arteries, cerebral arteries, lower limb arteries, lower limb veins, aortic arch, valve stone removal, cardiovascular and cerebrovascular thrombolysis and other fields in the human blood vessels. .

Example 2

Still taking the collection of lesion debris broken by the shock wave balloon as an example, in the present embodiment, a human body intraluminal collection device is provided, which also includes a conveying device, a capture net 200 and a support device, and preferably also has a control line 500. Different from the above-mentioned embodiment 1, the support device in the present embodiment is configured as a plurality of expandable stents 400, rather than the grid 300 in the embodiment 1; the other structures are the same as those in the above-mentioned embodiment 1, and the features already recorded in the above-mentioned embodiment 1 are naturally inherited in the present embodiment and will not be repeated.

5 and 6, in a preferred embodiment, the supporting device includes a plurality of expandable stents 400. Preferably, at least one expandable stent 400 is disposed at the entrance of the capture net 200, and the distal end of the expandable stent 400 is fixedly connected to the entrance of the capture net 200; preferably, at least one expandable stent 400 is disposed on the inner side of the recessed portion 230 of the capture net 200; the expandable stent 400 is capable of radially expanding to support the capture net 200; preferably, the proximal end of the expandable stent 400 is slidably connected to the conveying device, and the distal end of the expandable stent 400 is fixedly connected to the conveying device.

As shown in Figure 5, in a preferred embodiment, the expandable stent 400 includes a plurality of struts, the proximal ends of the plurality of struts converge into a ring shape, or are connected to an annular structure (not shown in the figure), the annular structure is sleeved on the conveying device, and is used to slide with the conveying device, and the annular structure is connected to a control line 500 (not shown in the figure, please refer to the accompanying drawing corresponding to the above embodiment 1), and the radial contraction of the expandable stent 400 is achieved by withdrawing the control line 500; the distal ends of the plurality of struts also converge in a ring shape and are fixed on the conveying device; more preferably, the struts are configured to have a bent shape, and the bending direction is radially outward, and a fulcrum 410 is formed at the bend to support the capture net 200.

In a preferred embodiment, the outer diameter of the expandable stent 400 matches the inner diameter of the human body lumen to ensure that the capture net 200 can fit closely to the tube wall and increase the efficiency of debris collection in the blood vessel.

Preferably, the outer diameter of the expandable stent 400 disposed in the inner recess 230 is smaller than the outer diameter of the expandable stent 400 disposed at other positions, so as to form the inner recess 230 of the capture net 200 and reduce the overflow of the debris collected by the first section 211 .

Preferably, the expandable stent 400 is made of a shape memory alloy, such as nickel-titanium alloy. After the expandable stent 400 is delivered to the specified position, it can radially expand to a prefabricated shape, and the withdrawal control line 500 can control it to shrink. Furthermore, since the shape memory alloy material has a certain elasticity and can undergo elastic deformation, it ensures that the expandable stent 400 can maintain a good fit with the inner wall of the blood vessel cavity during radial expansion, so as to further increase the efficiency of debris collection in the blood vessel and avoid the occurrence of debris escape.

Specifically, when the capture net 200 is in a transport state in the guide catheter, the expandable stent 400 is in a compressed state. When the capture net 200 is pushed out of the guide catheter and released, the expandable stent 400 self-expands, and the fulcrum 410 can support the capture net 200. When withdrawing the collection device from the human body's lumen, the control line 500 is withdrawn, so that the multiple expandable stents 400 shrink one by one to reduce their radial dimensions and increase the passability of the collection device in the human body's lumen.

When multiple expandable stents 400 are provided, the proximal ends of the multiple expandable stents 400 can be fixedly connected to the same control line 500, or can be respectively connected to different control lines 500, so that the physician can selectively control the expansion and contraction of different expandable stents 400. For details, please refer to the above-mentioned embodiment 1, which will not be repeated here.

Preferably, after the operation is completed, the expandable stent 400 located in the inner recess 230 is first retracted so that the debris is sealed in the first section 211, and then the expandable stent 400 located at the entrance is retracted to prevent a small amount of debris overflowing from the first section 211 from further overflowing from the second section 221 out of the capture net 200. Finally, the retraction of other expandable stents 400 (such as the expandable stent 400 arranged at the first end 210) is controlled. By selectively controlling the degree of retraction of the first grid 310 according to the volume of the debris collected in the first section 211, it is ensured that there is enough space for the debris to remain, and the first section 211 is prevented from excessively squeezing the debris and causing its escape.

Optionally, in this embodiment, the number and size of the expandable stents 400 may be determined according to the size and axial length of the capture net 200, and examples are not listed one by one here.

As shown in Fig. 6, in this embodiment, preferably, the edge of the entrance of the capture net 200 is provided with a radially outward extension 240; preferably, the entrance of the capture net 200 is inclined, and the angle between the entrance and the inner wall of the blood vessel cavity is not equal to 90°; preferably, a one-way membrane 600 is provided inside the entrance of the capture net 200; preferably, a layered inner net 250 is further provided between the inner concave portion 230 and the first end 210, and the layered inner net 250 has a larger mesh size than the capture net 200. The specific configuration of the above-mentioned structures is as in the above-mentioned embodiment 1, and will not be repeated here.

Those skilled in the art should understand that the application scenario in the blood vessel cavity provided in this embodiment is only an example. In fact, the above-mentioned collection device in the human lumen can be applied to interventional surgeries in the reproductive system, ear canal , digestive system, urinary system, nervous system and coronary arteries, cerebral arteries, lower limb arteries, lower limb veins, aortic arch, valve stone removal, cardiovascular and cerebrovascular thrombolysis and other fields in the human blood vessels.

In this embodiment, a balloon catheter is provided, which also includes a human intraluminal collection device as in the above-mentioned embodiment 1 or 2. The technical features already included in the above-mentioned embodiment 1 or 2 are naturally inherited in this embodiment and will not be described one by one.

Preferably, the balloon catheter comprises a balloon and a collection device in the human lumen, and the balloon is arranged on a conveying device of the collection device in the human lumen, and the conveying device is configured as a catheter 100, that is, the balloon and the capture net 200 share the same catheter, and both are fixed on the same catheter. Preferably, the balloon is arranged at the proximal end of the capture net 200.

In another optional embodiment, the balloon is disposed on the catheter 100, and in this case, the delivery device of the collection device in the human lumen is preferably configured as a guide wire to pass through the balloon catheter.

Optionally, the balloon in this embodiment can be a common balloon, a shock wave balloon, a cutting balloon or a spinous process balloon. When the balloon is working, the debris of the lesion flows distally with the blood flow and is collected by the capture net 200 to prevent the debris from escaping distally.

In this embodiment, the balloon catheter can be used in the digestive system, urinary system, reproductive system, reproductive system, respiratory system, lymphatic system and coronary arteries, cerebral arteries, lower limb arteries, lower limb veins, aortic arch, valve stone removal, cardiovascular and cerebrovascular thrombolysis and other fields in the human body.

Example 4

In this embodiment, a thrombus removal device is provided, which also includes a human intraluminal collection device as in the above-mentioned embodiment 1 or 2. The technical features already included in the above-mentioned embodiment 1 or 2 are naturally inherited in this embodiment and will not be described one by one.

In a preferred embodiment, the thrombectomy device further comprises a catheter, which may be a common catheter, a suction catheter, or a thrombolytic catheter. In this case, the delivery device of the collection device in the human lumen is preferably configured as a guide wire to pass through the catheter of the thrombectomy device, and the capture net 200 is disposed at the distal end of the catheter to capture debris from the lesion.

In a preferred embodiment, the thrombus removal device further comprises a stent, which may be a common stent or a thrombus removal stent; optionally, the stent is disposed on a catheter, in which case the delivery device of the intraluminal collection device is preferably configured as a guide wire to pass through the catheter of the thrombus removal device; optionally, the stent and the capture net 200 share the same delivery device, in which case the delivery device is configured as a catheter 100, and the stent and the capture net 200 are disposed on the same catheter.

In this embodiment, the thrombectomy device can be used in interventional surgeries in multiple fields such as the reproductive system, ear canal, digestive system, urinary system, nervous system, as well as the coronary arteries, cerebral arteries, lower limb arteries, lower limb veins, aortic arch, valve stone removal, cardiovascular and cerebrovascular thrombolysis, etc. in the human body.

The embodiments of the present invention are described above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned specific implementation methods. The above-mentioned specific implementation methods are merely illustrative and not restrictive. Under the guidance of the present invention, ordinary technicians in this field can also make many forms without departing from the scope of protection of the present invention and the claims, all of which are within the protection of the present invention.

Claims (8)

1. A collection device in a human lumen, characterized in that: It includes a conveying device and a supporting device; The conveying device is axially arranged at the central axis of the collecting device in the human body lumen, and the conveying device is used to convey the supporting device into the human body lumen; The support device includes a plurality of expandable stents; One end of the expandable stent is fixedly connected to the second end, and the expandable stent is at least capable of radial expansion; One end of the expandable stent is slidably connected to the delivery device, The diameter of at least one of the expandable stents is smaller than that of the other expandable stents, and the expandable stent with a smaller diameter is arranged in the middle of the expandable stent with a larger diameter, so that the support device forms an inner concave portion. 2. The human body intraluminal collection device according to claim 1, further comprising: Capture net; the support device is arranged in the capture net and is used to control the capture net; The capture net comprises a first end and a second end, the first end is sealed and fixedly connected to the conveying device, and the second end is open and serves as an entrance to the capture net; The first end and the second end are arranged opposite to each other at two axial ends of the capture net. 3. The human body intraluminal collection device according to claim 2, characterized in that the supporting device comprises a plurality of grids, the grids are in the shape of a net disk and can be radially expanded, the grids are fixedly connected to the inner side of the capture net, and are used to control the capture net; At least one end of the grid is slidably connected to the conveying device. 4 . The human body intraluminal collection device according to claim 2 , wherein the supporting device is disposed at both the first end and the second end of the capture net. 5. The human body intraluminal collection device according to claim 2, characterized in that the edge of the second end of the capture net is provided with an outward extension portion, and the extension portion is in a skirt shape for abutting against the inner wall of the lumen. 6. The human body intraluminal collection device according to any one of claims 1 to 5 is characterized in that it also includes a control line, the distal end of the control line is connected to the support device, and is used to control the radial expansion or contraction of the support device, and the proximal end of the control line is arranged along the axial direction of the conveying device and extends to the proximal end of the conveying device. 7. A balloon catheter, characterized in that it comprises the human body intraluminal collection device as described in any one of claims 1 to 6, and also comprises a balloon, wherein the balloon is arranged on a conveying device, and the balloon comprises an ordinary balloon, a shock wave balloon, a cutting balloon or a spinous process balloon. 8. A thrombus removal device, characterized in that it comprises the human body intraluminal collection device according to any one of claims 1 to 6, and further comprises a catheter and/or a stent; The catheters include common catheters, aspiration catheters, and thrombolytic catheters; The stent includes a common stent or a thrombectomy stent.